Checkpoint

Advanced Neurodevices for Better Patient Outcomes

Checkpoint Surgical速 22901 Millcreek Blvd., Suite 110 Cleveland, Ohio 44122 Toll-free: 877.478.9106 Local: 216.378.9107 Fax: 216.378.9116 www.checkpointsurgical.com

Checkpoint Surgical Advanced Neurodevices for Better Patient Outcomes Many of the 45 million+ surgeries performed in the U.S. each year pose a significant risk of intraoperative nerve injury or require careful nerve repair.

Checkpoint Surgical provides surgeons with state-of-the-art neurodevices to locate and identify nerves and evaluate nerve and muscle function in surgical procedures.

Providing surgeons with the proper tools promoting “neuroprotective surgery” helps them make better surgical decisions with greater confidence.

Checkpoint Surgical targets an estimated neuroprotective surgery market over the next ten years of more than $3 billion.

In 2010, Checkpoint Surgical initiated the commercial launch of the CHECKPOINT® Stimulator/Locator, the first product in a line of proprietary, patent-protected neuromuscular surgical devices.

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CHECKPOINT Market Acceptance

NeuroInsights identified Cleveland among the regions to watch worldwide as it is ranked #5 in the world for neurological health care and #6 for neurodevice companies.

CHECKPOINT® has demonstrated market acceptance and is used by prominent surgeons in a wide range of surgical procedures in numerous hospitals across the United States, including:

Checkpoint Surgical products are manufactured in the USA.

Akron Children’s Hospital, Akron, OH

What Surgeons Are Saying ® About CHECKPOINT :

Checkpoint Surgical is headquartered in Cleveland, Ohio, a leading center for neurodevice research and development.

“CHECKPOINT’s reliable and reproducible stimulation has helped not only to identify and protect nerves from injury, but also has proven very useful in nerve reconstruction cases. I have come to rely more on the CHECKPOINT® than the electrophysiologic data.”

Michael Hausman, M.D.,

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Lippmann Professor of Orthopedic Surgery, Vice-Chairman, Department of Orthopedic Surgery, Chief, Hand and Elbow Surgery, Mount Sinai Medical Center (NY)

CHECKPOINT Stimulator/Locator A Significant Advance In Neuroprotective Surgery

CHECKPOINT® is used in a variety of orthopaedic, reconstructive plastic, trauma, peripheral nerve and ENT procedures representing a potential annual revenue opportunity in excess of $300 million.

Common CHECKPOINT® procedures include: Brachial Plexus Procedure; Shoulder and Elbow Revision; Nerve Exploration/Repair; Nerve Transfer; Tendon Transfer; Tumor Resection; Facial Reanimation; Parotidectomy; and Thyroidectomy.

CHECKPOINT® is a state-of-the-art device that delivers significant value to the surgeon, hospital and patient, helping: Surgeons reduce the risk of intra-operative nerve injury Facilitate nerve location and identification in challenging anatomical conditions Increase surgeon confidence by providing reliable and objective information Mitigate malpractice liability concerns associated with intra-operative nerve injury

Barnes Jewish Hospital, St. Louis, MO Bayfront Medical Center, St. Petersburg FL James J. Peters VA Medical Center, Bronx, NY Cleveland Clinic, Cleveland, OH Copley Hospital, Stowe, VT Durham VA Medical Center, Durham, NC George Washington University Hospital, Washington, DC Hospital for Joint Diseases, NYU Langone Medical Center, New York, NY Hospital for Special Surgery, New York, NY Loyola University Medical Center, Chicago, IL

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Designed by a world-class team of surgeons and biomedical engineers, CHECKPOINT® provides versatile, reliable and safe nerve and muscle stimulation that is fully controlled by the surgeon in support of surgical procedures that require careful and precise soft tissue dissection or nerve repair.

Balboa Naval Hospital, San Diego, CA

“CHECKPOINT® is far superior to any nerve stimulator we have used in the past and is indispensible for my brachial plexus and complex nerve repair cases.”

Maimonides Medical Center, Brooklyn, NY

Scott H. Kozin, M.D.,

Montefiore Medical Center – Weiler Hospital, Bronx, NY

Professor, Orthopaedic Surgery, Temple University and Hand & Upper Extremity Surgeon, Shriners Hospitals for Children

Mayo Clinic Arizona, Scottsdale, AZ Miami Children’s Hospital, Miami FL

Mount Sinai Medical Center, New York, NY Nationwide Children’s Hospital, Columbus, OH

“Finally, a well-designed disposable stimulation device that puts precision and control in the surgeon’s hand – a must for every peripheral nerve surgeon.”

Justin Brown, M.D.,† Assistant Professor of Neurological Surgery, Director of Peripheral Nerve Surgery at University of California, San Diego; Co-Director at Center for Neurophysiology and Restorative Neurology

“CHECKPOINT® has become an essential tool for my complex shoulder surgery cases, not only to help identify and protect nerves from injury, but also to gauge how well they are functioning.”

Evan L. Flatow, M.D., Lasker Professor and Chair, Chief of Shoulder Surgery, Leni & Peter W. May Department of Orthopaedic Surgery, Mount Sinai Medical Center (NY)

Riverside Methodist Hospital, Columbus, OH Shriner’s Hospital for Children, Philadelphia, PA Scripps Green Hospital, San Diego, CA Shady Grove Adventist Hospital, Rockville, MD Southeastern Regional Medical Center, Lumberton, NC St. Alphonsus Regional Medical Center, Boise, ID Stony Brook University Medical Center, Stony Brook, NY Timonium Surgery Center, Lutherville, MD UCSD Medical Center, San Diego, CA University of Chicago Medical Center, Chicago, IL University of North Carolina Medical Center, Chapel Hill, NC USC Medical Center, Los Angeles, CA VCU Medical Center, Richmond, VA

† Dr. Hausman is a paid consultant of and has a financial interest in Checkpoint Surgical.

Dr. Brown is a paid consultant of Checkpoint Surgical.

Management Team The Checkpoint Surgical management team has extensive experience and a track record of success in medical device development and commercialization President & CEO, Director

Chairman of the Board

Len Cosentino served as VP Strategic Initiatives and General Counsel for NDI Medical since 2006 and was the principal architect of the sale to Medtronic of NDI’s MedStim product for $42 million. Mr. Cosentino has more than 20 years of experience providing legal, finance and business counsel to early stage companies and venture firms.

Geoff Thrope is a leading entrepreneur in the field of neurostimulation with more than 30 years experience in research and commercialization of neurostimulation medical devices.

Mr. Thrope is founder, CEO and President of NDI Medical, a premier medical device development company.

Vice President of Sales

Chief Medical Advisor

Steve Jacobs has over 20 years of medical sales, sales management and business development experience primarily with various Abbott & J&J operating companies. Most recently he served as Area Vice President for Depuy Spine playing a key role in the restructuring and enhanced sales performance of the Mountain Area.

Dr. Michael Hausman is the Robert K. Lippman Professor and Chief of Hand, Elbow and Microvascular Surgery at the Mount Sinai Medical Center. Dr. Hausman serves as a consultant editor for the Journal of Bone and Joint Surgery, Clinical Orthopedics and Related Research and the Journal of the American Academy of Orthopaedic Surgery.

Director of Training and Education

Director of Operations

Kevin Scanlan has over 25 years clinical experience in the medical device industry including 13 years in neurostimulation device training and clinical studies. Mr. Scanlan previously worked at NDI Medical and Advanced Bionics. Mr. Scanlan is also a licensed (Florida) Occupational Therapist.

Terri Zmina has over 20 years clinical and management experience in the healthcare industry, including 10 years in the neurostimulation industry working in reimbursement, market analysis and intellectual property development. Ms. Zmina is a licensed (Ohio) Physical Therapist and has an MBA in Health Care Administration.

Director

Director

Since 1986, Scott Zeilinger has owned, operated and invested in highly successful entities specializing in healthcare, branded consumer products, entertainment, and commercial real estate, including Magic American Corporation.

Don Hubbard serves as VP of Sales and Marketing for PartsSource, a multi-modality medical parts supplier, where he led sales growth from $5 million to $110 million. Mr. Hubbard is the 2005 winner of the DMSE Sales Executive of the year for Northern Ohio.