Dose Prediction Models Catalogue USA version September 26 2025

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DEEP LEARNING DOSE PREDICTION MODELS

MACHINE LEARNING FASTER AND SMARTER TREATMENT PLANNING

Generate treatment plans automatically with deep learning driven dose prediction. RaySearch provides your clinic with a roster of machine learning models that have been validated against common radiotherapy treatment protocols. Details about the treatment protocols can be found in the respective model data sheets.

RSL BREAST LOCOREGIONAL 2LVS*

Validation patient example

MODEL OVERVIEW

Treatment site

Breast (or thoracic wall) and nodes

Modality Photons

Treatment technique

Validated for VMAT

Primary prescription [cGy] 6000

Number of fractions 25

Dose per fraction [cGy] 240

MODEL PROTOCOL

Clinical goals varied based on primary target (either breast or thoracic wall) and the involved lymph nodes. Clinical goal values given in the table below represent the ones used for breast with all lymph nodes involved.

ROI

PTV1

PTV1

PTV1

PTV2

PTV2-PTV1

PTV3

PTV3

PTV4

PTV4

PTV5

PTV5

PTV6

PTV6

Organs at risk

Clinical goals

At least 5989 cGy average dose

At least 5700 cGy dose at 99.1 % volume

At most 6180 cGy dose at 0.5 % volume

At least 4750 cGy dose at 98.4 % volume

At most 5250 cGy dose at 9.6 % volume

At least 4750 cGy dose at 99.2 % volume

At most 5250 cGy dose at 0 % volume

At least 4750 cGy dose at 96.0 % volume

At most 5250 cGy dose at 0.1 % volume

At least 4750 cGy dose at 98.0 % volume

At most 5250 cGy dose at 0.1 % volume

At least 4750 cGy dose at 96.2 % volume

At most 5250 cGy dose at 0.6 % volume

Clinical goals varied based on primary target volume and lymph node involvement

*This functionality is in RayStation v2025 SP1, which is pending FDA 510(k) clearance and is not currently available for sale or clinical use in the United States.

ADVANCING CANCER TREATMENT

RaySearch Laboratories AB (publ) is a medical technology company that develops innovative software solutions for improved cancer treatment. RaySearch® markets the RayStation®* treatment planning system (TPS) and the oncology information system (OIS) RayCare®*. The most recent additions to the RaySearch product line are RayIntelligence® and RayCommand®*. RayIntelligence is an oncology analytics system (OAS) which enables cancer clinics to collect, structure and analyze data. RayCommand®**, a treatment control system (TCS), is designed to link the treatment machine and the treatment planning and oncology information systems.

RaySearch software is used by over 2,600 clinics in more than 65 countries. The company was founded in 2000 as a spin-off from the Karolinska Institute in Stockholm and the share has been listed on Nasdaq Stockholm since 2003.

*Subject to regulatory clearance in some markets.

**RayCommand is not available for use or sale in the USA or Canada.

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Dose Prediction Models Catalogue USA version September 26 2025 by RaySearch Laboratories - Issuu