What Exactly Is CBD Isolate? CBD isolate includes no tetrahydrocannabinol, other cannabinoids, or plant matter, making it the purest form of cannabidiol (CBD) available. Extracted from the hemp plant, it is frequently the most reasonable alternative for people who are sensitive to or must avoid THC. Hydrogenated CBD Wholesale isolation may aid in the treatment of anxiety, sleeplessness, and chronic pain. The isolate version, on the other hand, removes any additional cannabinoids, terpenes, or flavonoids, removing the possibility of entourage effect advantages.