10th International ISSX Meeting Preliminary Program and Registration Brochure

Student/Postdoc

Student/Postdoc

10:40 – 11:20 Pathway Informed Metabolomics Discovery Profiling AS A Tool For Targeted Proteomics Analysis

SUNDAY, SEPTEMBER 29, 2013 18:15 – 21:30 18:15 – 18:45

18:45 – 19:30 KEYNOTE LECTURE: Systems Pharmacology – Systems Biology meets Drug Discovery & Development

19:30 – 21:30

07:45 – 08:45

Concurrent Industry-Sponsored Symposia: 1: Promega Corporation | 2: Thermo Scientific

11:00 – 12:00 ISSX AWARDS SESSION Presentation of the R.T. Williams Distinguished Scientific Achievement Award to Yuichi Sugiyama, Ph.D. Presentation of the Frederick J. Di Carlo Distinguished Service Award to Robert P. Hanzlik, Ph.D.

18:00

Student and New Investigators Reception

07:45 – 08:45

Concurrent Industry-Sponsored Symposia: 1: Bruker Daltonics| 2: Corning Incorporated

Michael Aleo, Pfizer, Global Research and Development, Groton, Connecticut, USA

12:30 – 12:45 | Abstract Presentation: ATP METABOLISM IN RBC AS IN VIVO BIOMARKER FOR CARDIOVASCULAR TOXICITY

12:30 – 12:45 | Abstract Presentation: TOWARDS A MORE PREDICTIVE MODEL: EFFECT OF TELMISARTAN ON TAUROCHOLATE DISPOSITION IN B-CLEAR® CRYOPRESERVED SANDWICH-CULTURED HEPATOCYTES COMPARED TO BSEPEXPRESSING MEMBRANE VESICLES

11:30 – 12:00 Mitochondria-Targeted Therapeutics

07:45 – 08:45

Concurrent Industry-Sponsored Symposia: 1: Hepregen Corporation | 2: Bioreclamation IVT

09:00 – 09:30 Novel Mechanistic Biomarkers of Drug-induced Liver Injury

12:30 – 12:45 | Abstract Presentation: TRANSLATIONAL PBPK MODELING AND SIMULATION OF THE HEPATIC DISPOSITION OF ACTIVELY TRANSPORTED DRUGS BASED ON INDIVIDUAL TRANSPORTER ASSAYS

12:30 – 12:45 | Abstract Presentation: DRUG ACCUMULATION IN ALVEOLAR MACROPHAGES: ASSESSMENT OF UPTAKE AND LYSOSOMAL DISTRIBUTION IN VITRO

14:30 – 15:00 Integrated Examination of Ah Receptor-Mediated Hepatic Fat Accumulation Tim Zacharewski, Michigan State University, East Lansing, Michigan, USA 15:00 – 15:30 Pharmacometabolomics: Global Biochemical Approach for Mapping Drug Effects Rima Kaddurah-Daouk, Duke University, Durham, North Carolina, USA 15:30 – 16:00 Mechanistic Understanding and Biomarkers for Drug Toxicity Using Metabolomics Lining Guo, Metabolon, Durham, North Carolina, USA 16:00 – 16:15 | Abstract Presentation: To Be Announced

12:15 – 16:30 | Abstract Presentation: To Be Announced

19:30 – 21:30 in the Exhibit Hall.