The benefits of 3D printing for drug development!

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THE BENEFITS OF 3D PRINTING FOR DRUG DEVELOPMENT

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THE BENEFITS OF 3D PRINTING FOR DRUG DEVELOPMENT Keywords:Â Pharmaceutical technology, Impresion 3D, Drug development

Introduction 3D printing is a manufacturing process in which layer

materials to

form

advantages complex making

it

an

in

and

are

deposited

entity.

the

This

great

of

highly

production

economical

by

has

custom-designed

more

layer

products,

and

time-

saving. Presently, applied pharmaceutical 3D

printing

modeling

includes

(FDM),

appearance

(SLA),

fused

stereo and

deposition lithographic

binder

extrusion

Figure 1 . Based on the diagnosis, treatment, and

printing. 3D printing can be used to make

treatment plan, doctors print the drug where

molds

needed to suit the specific situation of each

to

directly

produce

using

materials.

pills

or

powdered

to

print

drugs

as

pills, raw

patient. Printed drugs have a precisely measured API (Active Pharmaceutical Ingredient).

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Custom 3D printed tablets

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3D printing improves drug delivery route

The

individual

their

characteristics

eating

habits,

of

people,

inheritances,

be

it

ethnicities,

3D

printing

technology

produce

to

reduce

quality of life and even the disease itself have

loose,

effects

swallowing difficulties, as in the case of

on

the

pharmacokinetics

pharmacodynamics

of

drugs,

and

however

3D

porous

can

making

fast

disintegrating

printing is a highly flexible process that allows

printing

designing

microneedles.

the

pill

size

or

fill

percentage

to

tablets

can

also

be

This

technique

tablets.

used

to

make

technology to

administer

3D

is a

a

precisely control the dose to meet the individual

painless

drug

needs of each patient.

through the skin, since the microneedles penetrate the skin and release the drug

Improvement in controlled drug

into

release 3D

pain

printing

structure

of

can

adjust

the

the

tablet

by

shape

and

selecting

internal

materials,

setting parameters, and designing models. You can control the release rate or time of the drug because the release curve of the printed tablets is linked to the shape of the drugs. The custom shape

created

by

3D

printing

changes

the

the

dermis

nerve,

so

without it

administration

is

of

stimulating

very

useful

drugs

the

in

the

such

as

transdermal insulin. In addition, new ways of using drugs have been achieved, such as

the

implantable

nanofluids

for

delivery

topical

device

with

immunotherapy

of

tumors.

Outlook into the future

surface area of the pill, which can control the strength and time of drug release. In addition, it is very useful for patients who require multiple medications suffering from several diseases. 3D printing

also

multiple

medications

polymers the

in

solves

a

single

different

independently

the

problem

compatible

in

with

formulation,

medications different

of

having multiple

ensuring

are places

that

released and

at

Although

3D

deficiencies

printing and

technology

high

cost,

as

has new

technologies develop, little by little it can be solved. In the future it is anticipated that

the

testing

effect of

improved,

of

medication

patients and

3D

will

and

be

printing

drug

greatly can

be

implemented in pharmacies and hospitals to improve people's quality of life.

different times.

3D bioprinting helps drug development 3D

bioprinting

drugs

are

could

help

approved

drug

by

trials

as

new

two-dimensional

cytology, animal testing, and clinical trials so it can

mimic

the

physiological

characteristics

of

living organs and perform drug testing on behalf of animals. In addition, it is very useful to find out the toxicity levels of new drugs.

All credits of scientific information are for the authors of the scientific article creation!

Scientific information reference: Xiao Zhu, H. L. (2020). 3D printing promotes the development of drugs. Biomedicine & Pharmacotherapy, 1-6.

Link: https://www.sciencedirect.com/science/article/pii/S0753332220308374#tbl0005

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