Page 1

R

ST.

RD .

WI

LK

INS

P Garage 1

UR

P McGovern Commons &

Research Institute

OO Ben Taub General Hospital

Baylor College of Medicine

MO

ST.

HOUSTON METHODIST RESEARCH INSTITUTE

C

Trevisio

SU

ND

MOLECULAR DIAGNOSTICS CORE

ST.

Texas Children’s Neurological Research Institute

UNIVERSITY OF HOUSTON

Texas Children’s Texas Hospital Heart St. Luke’s Institute Hospital

M.D. Anderson Cancer Center

JOHNSON AVE.

BATES ST.

MAP LEGEND METRORAIL

M.D. ANDERSON BLVD.

BLV

D.

HWY 288

D. BLV

OD

O SW

AE

BR

HOLCOMBE BLVD. SOUTH LOOP 610

ACCOMODATIONS

P

PARKING

NIN UN

ITY

JO

HN

P

BLV

D.

Smith Tower

AIN UT

HM

Scurlock Tower

SO

6670 Bertner Avenue Houston, TX 77030

houstonmethodist.org/research

SO

UT

HG

AT E

EN

Marriot

A

RD .

ST.

A

Hilton Houston Plaza/ Medical Center

P

DR YD

FA NN IN

Core Director: Randall J. Olsen, MD, PhD 713.441.6802 Email: rjolsen@houstonmethodist.org

Houston Methodist Fondren Building

R P Garage 1

EE

MA

INS

SS

EN

NB

LV D.

E.

Mary Gibb Jones Building

AV E.

. ST

L UL

C

UR

P McGovern Commons &

ST ER LIN G

Baylor College of Medicine MO

ST.

Trevisio

SU

ND

ST.

Texas Children’s Neurological Research Institute

BLV

D.

Texas Children’s Texas Hospital Heart St. Luke’s Institute Hospital

SON AVE.

BATES ST. HMRI Communications & External Relations | RICORE-018 | MM | DH | 250 | 08.2014

WI

LK

Research Institute

FR

P Garage 7

Jones Tower

ST.

Rice Bioscience Research Collaborative

Molecular Diagnostics Core

houstonmethodist.org/molecular-diagnostics

RS

RO

University of Texas Health & Science

P Outpatient Center

RICE UNIVERSITY

IVE

Houston Methodist Research Institute

Memorial Hermann Hospital

FA N

N

Core Staff: Dilzi Mody 713.441.1771 Email: dfmody@houstonmethodist.org

IDG

HM

A

UT

DRYDEN/TMC METRORAIL STATION

BR

SO

R

CA M

AIN

FONDREN BUILDING

ST.

NIN

Fondren Building

E.

M.D. Anderson Cancer Center

M.D. ANDERSON BLVD.

A

LV D.

Mary Gibb Jones Building

. ST

L UL

ST.

Marriot

EN

NB

BERTNER AVE.

HG

AT E

EN

MA

P Garage 7

Jones Tower

Houston Methodist

EE

AV E.

SO UT UT

P

Scurlock Tower

FR

NG

Smith Tower

MI

D.

FA N

SO

A

Hilton Houston Plaza/ Medical Center

DR YD

HN

BLV

HM AIN

Rice Bioscience Research Collaborative

JO P

AV E.

RF LE

ITY

ST ER LIN G

MA

RS

SS

LA

IVE

RICE UNIVERSITY

ST.

UN

P Outpatient Center

TA UB L

N

RO

University of Texas Health & Science

P

Hermann Hospital

FA NN I

PARKING

BERTNER AVE.

P


Molecular Diagnostics Core

The Houston Methodist Research Institute Molecular Diagnostics Core facility provides Houston Methodist investigators and the Texas Medical Center community with access to advanced molecular tools for research studies. All equipment is conveniently located in the Molecular Diagnostics Core Laboratory in Fondren 554. User training and instrument reservations can be scheduled using iLab.

FACILITY The Molecular Diagnostics Core provides investigators access to cutting-edge instrumentation for expression analysis, SNP genotyping, and other molecular assays. Some of the available technologies include: Capillary Electrophoresis – The Agilent 2100 is a microfluidics-based platform offering solutions for the analysis of DNA, RNA, proteins and cells. Typical applications include: • RNA sample QC prior to microarray or qPCR experiments • DNA Analysis of PCR/mPCR and RT-PCR products • Protein expression analysis • Protein purity during purification • Cell-based analysis in gene silencing or apoptosis Spectrophotometry – The NanoDrop® ND-1000 UV-Vis Spectrophotometer enables highly accurate analyses with remarkable reproducibility, eliminates the need for cuvettes and capillaries, and need for most dilutions. This technology is used for: • Nucleic Acid Measurement • Microarray labeling QC • Protein Measurement • Cell Culture Microarray Instrumentation – The Affymetrix GeneChip® Instrument System is one of the most advanced microarray analysis platforms available to generate reliable, Gene Expression Analysis and DNA Analysis data. The Dell Precision 490 workstation accompanies the GeneChip System.

THE GENECHIP® INSTRUMENT SYSTEM

Software • Affymetrix Software • Partek Genomics Suite

Our Specialized Services The core offers training for the use of instrumentation, assistance in the design of experimental protocols, and ongoing consultation and support. Core instrumentation is available for self-use by trained investigators.

Molecular Diagnostics Core  
Molecular Diagnostics Core