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houstonmethodist.org/biostatistics

6670 Bertner Avenue Houston, TX 77030

houstonmethodist.org/research HMRI Communications & External Relations | RICORE-006 | RH | DH | 250 | 04.2014

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Director: Leif Peterson, Ph.D.

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Request services online: houstonmethodist.org/biostatistics

713.441.6121 (phone) | 713.441.5123 (fax) Email: lepeterson@houstonmethodist.org

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The Center for Biostatistics provides statistical analysis, data management, and high performance computing services to internal and external research teams. It is located in the heart of the Texas Medical Center on the Houston Methodist campus.

HOUSTON METHODIST RESEARCH INSTITUTE

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“The Biostatistics Core has been a fundamental

The Center for Biostatistics

asset in our research projects. Under the leadership of Dr. Peterson, they have been

Statistical Analysis Services • Study design and conceptualization

The Center for Biostatistics is a fee-for-service Core which provides consultation on study design and analyses to grant/contract-supported investigative research teams and clinical research groups. Center personnel participate in grants, contracts, teaching and private consultations. Altogether, the cumulative experience of core personnel in statistics, mathematics, computation and data management exceeds 50 years.

consistently prompt and responsive to our requests and have been eager to collaborate in major grant applications. We have

• Data collection, storage/retrieval, warehousing

successfully competed for NIH funding with

• Sample size determination and statistical power

an application that required sophisticated

• Percentage points for discrete and continuous probability distributions (Binomial, Poisson, Standard Normal, Student’s t, F-ratio, Laplace, Skew-Normal, Logistic, etc.)

and committed statistical support. It simply would not have been possible without their help.” Miguel Valderrábano, M.D., FACC, Houston Methodist DeBakey Heart & Vascular Center

• Monte Carlo simulation and uncertainty analysis • Inferential hypothesis testing • Linear models (ANOVA, ANACOVA, MANOVA, regression)

Hardware/ Statistical Software

• Categorical modeling (log-linear, linear categorical regression, logistic regression) • Univariate and multivariate regression modeling and diagnostics

• Computational resources: high performance

• Survival and propensity scoring analysis

• Data mining & pattern recognition software:

• Longitudinal data analysis (GLM, GEE, RMANOVA) • Bioinformatics (microarray QC, normalization, gene profile identification, cluster, heat maps) • Data mining (knowledge discovery and pattern recognition in data/images, unsupervised class discovery, supervised class prediction, nonlinear dimensional reduction, duo-mining)

computing cluster and work stations

Peltarion synapse, Predictive Dynamix, StatSoft Data Miner, Golden Helix, MatLab • Statistical software: bulk analytical analysis (Stata and R Bioconductor), power and sample size determination (PASS 12), data analysis (SAS & SPSS) • Other: Minitab, Sigmastat, Sigmaplot

Biostatistics Core  
Biostatistics Core