Active ingredients
Adverse Drug Events
0.5% Permethrin*1 (1) Short-term side effects in sensitive individuals include eye, skin, nose, and throat irritation, and may include breathing problems. Signs and symptoms of poisoning following very high exposure include abnormal facial sensation, dizziness, salivation, headache, fatigue, vomiting, diarrhea, and irritability to sound and touch. Pulmonary edema, seizures, and fasciculations may occur in more severe cases. (3)
Doesn't contain any chemical materials, no side effects
When people get permethrin on their skin, they may have irritation or tingling, burning and itching at that spot. If permethrin gets in the eyes it can cause redness, pain or burning. If people eat permethrin it could cause sore throat, abdominal pain, nausea and vomiting. People that have breathed in permethrin have had irritation in the nose and lungs, difficulty breathing, headaches, dizziness, nausea and vomiting. (6) Less than 1% of the permethrin put on the skin of people was taken into the body. If permethrin is eaten, most of it is quickly absorbed. The pyrethroids easily pass through the lungs into the body if inhaled, but no specific data on permethrin was found.
Elimination from the body
Ultrasonic tick repeller - Tickless technology
Once permethrin is absorbed, it quickly moves throughout the body. The greatest amounts of permethrin have been found 3 to 4 hours after it was eaten. Permethrin leaves the body mainly in the urine, but may also be in the feces. In laboratory tests in rats, half of the permethrin was gone from the animals' bodies within a day. (6)
Safe to use for babies, elderly, ill or pregnant people. Well over 1 million pets were protected as well as millions of humans against zoonotic diseases that carried out by ticks, fleas and mites. Dust mite and FAD (Flea Allergic Dermatitis) elimination contributed to healthier life for allergic human.
Efficacy
100% effective in providing personal protection against adults of the Pacific Coast tick (9)
"94-97%" (10)
Duration of efficacy
Permethrin-treated clothes were effective against insects for 2 weeks to 6 months (5–20 detergent washings) (4)
Tickless Human: 3000 hours (switchable), Tickless Active: years (rechargeable)
Human exposure to large doses of permethrin may cause genotoxicity and immunotoxicity in humans and farm animals. However, it is classified by the EPA as a likely human carcinogen, based on a mouse reproduction test. (4)
Toxicity
The most common symptoms appear to be nausea and vomiting. Neurotoxicity appears to be most clinically significant. Permethrin toxicity may mimic organophosphate poisoning because of its cholinergic actions. (5)
Environment friendly, no harm to animals, reusable and recyclable
870.6300 Developmental Neurotoxicity Study (2) 870.1300 Acute Inhalation Toxicity Study (2) Permethrin is highly toxic to both freshwater and estuarine aquatic organisms. (2)
Impact on environment
Warnings
Environmentally friendly, contains no chemicals or fragrances, Tickless Mini is rechargeable (lower disposal rate)
Permethrin toxicity data show that the compound is highly toxic to honeybees, as well as other beneficial insects. (2) People can have skin exposure or breathe in products containing permethrin while applying the products, or during public health mosquito control efforts. Permethrin may be eaten if people forget to wash their hands after using products that contain permethrin. (6) Permethrin is recommended to be used as an insect repellent on clothing only and direct skin contact should be avoided. (4)
There is no age limit, can be used in puppies and kittens at any age. The product can be used during pregnancy, lactating period and in parallel during medication.
Safe for topical use in adults and children over the age of two months (8)
Precautious requirement
1
Apply to CLOTHING ONLY. Do not apply to skin. Immediately wash with soap and water if you get material on the skin. Do not apply to clothing while it is being worn. Apply before you put the clothing on. Apply in a well-ventilated area outdoors protected from the wind. Lightly moisten the fabric, do not saturate. Allow drying for 2 hours (4 in humid conditions). Allow clothing to dry prior to before wearing. Do not treat the clothing more than once every two weeks. Launder treated clothing at least once before retreating (7)
To prevent ticks, flea, mite diseases (Lyme-diseases etc.) it is recommended to use for human (hunters, nature lovers, cross-country runners, babies and children, gardeners, forest workers, horse riders, etc.)
EMA: * Non-centrally authorised medicines
SOURCES
European Medicine Agency (EMA)
1
https://www.adrreports.eu/en/search_subst.html#
Environmental Protection Agency (EPA) - Fact Sheet for Permethrin
2
https://www3.epa.gov/pesticides/chem_search/reg_actions/reregistration/fs_PC-109701_1-Jun-06.pdf
Permethrin fact sheet-City Health Information,The New York City Department of Health
3
https://health.maryland.gov/phpa/IDEHASharedDocuments/permethrin.pdf
National Center for Biotechnology Information (NCBI)
4
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6189689/
National Center for Biotechnology Information (NCBI)
5
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5598406/
National Center of Pesticide Information (NCPI)
6
http://npic.orst.edu/factsheets/PermGen.html
Maine Gov. Personal Protection from Ticks
7
https://www.maine.gov/dacf/php/gotpests/bugs/factsheets/personal-protection-from-ticks_caes-tickhandbook-2007_web.pdf
Wikipedia
8
https://en.wikipedia.org/wiki/Permethrin#Side_effects
Efficay of Permethrin as a repellent and toxicant for personal protection against the pacific coast tick and the pajaroello tick - Robert S. Lane and John R. Anderson
9
https://academic.oup.com/jme/article-abstract/21/6/692/2220308?redirectedFrom=fulltext
VCA Animal Hospitals, Camerino University
Website: www.PROTECTONEGLOBAL.com Email: info@protectoneglobal.com
10
https://tickless.com/certificates/