Since 1988, Instituto Marquês de Valle Flôr (IMVF) develops a broad program of reinforcement of the health sector in Sao Tome and Principe. With the support of the European Union, the Portuguese Cooperation, Calouste Gulbenkian Foundation, the Portuguese Directorate General for Health and in narrow partnership with the Government of Sao Tome and Principe, the program Health for All has put in place, during the last 25 years, a progressive and constantly growing strategy of capacity building and development of the health sector in that country.