All about Axitinib tablets What Axitinib is and what it is used for: This drug is a small molecule tyrosine kinase inhibitor. Axitinib (Brand name Inlyta) reduces the blood supply to the tumour and resists the growth of cancer. It is indicated in order to treat advanced kidney cancer (advanced renal cell carcinoma) in adults, when other medicines (sunitinib or a cytokine) are no longer stopping disease from progressing. Administration: The recommended dose is axitinib 5 mg twice a day. Tablets should be taken approximately 12 hours apart either with or without food. Tablets should be swallowed whole with water and not broken or crushed. Side Effects: The most commonly reported axitinib side effects include: • • • • • • • • • • • • •
diarrhea nausea hoarseness decreased weight vomiting constipation dehydration muscle pain dizziness nose bleeding high blood pressure decreased appetite tiredness or feeling weak
Report your healthcare professionals if you experience any adverse reactions that bothers or does not go away. What should I need to know before taking inlyta: Talk to your doctor prior to taking inlyta: • • • • • • • •
If you have high blood pressure. If you have thyroid gland problems. If you have had a recent problem with blood clots in your veins and arteries, including stroke, heart attack, embolism, or thrombosis. If you suffer from bleeding problems. If you have or have had an aneurysm or a tear in a blood vessel wall. If you are looking forward to an operation or if you have an unhealed wound. If while on treatment with this drug, you get symptoms such as confusion, headache, seizures (fits). If you have liver problems.
What should I avoid while taking axitinib? Do not drink grapefruit juice or eat grapefruit. The grapefruit may be responsible for in order to increase the amount of axitinib in blood.