All about Axitinib tablets What Axitinib is and what it is used for: This drug is a small molecule tyrosine kinase inhibitor. Axitinib (Brand name Inlyta) reduces the blood supply to the tumour and resists the growth of cancer. It is indicated in order to treat advanced kidney cancer (advanced renal cell carcinoma) in adults, when other medicines (sunitinib or a cytokine) are no longer stopping disease from progressing. Administration: The recommended dose is axitinib 5 mg twice a day. Tablets should be taken approximately 12 hours apart either with or without food. Tablets should be swallowed whole with water and not broken or crushed. Side Effects: The most commonly reported axitinib side effects include: • • • • • • • • • • • • •
diarrhea nausea hoarseness decreased weight vomiting constipation dehydration muscle pain dizziness nose bleeding high blood pressure decreased appetite tiredness or feeling weak
Report your healthcare professionals if you experience any adverse reactions that bothers or does not go away. What should I need to know before taking inlyta: Talk to your doctor prior to taking inlyta: • • • • • • • •
If you have high blood pressure. If you have thyroid gland problems. If you have had a recent problem with blood clots in your veins and arteries, including stroke, heart attack, embolism, or thrombosis. If you suffer from bleeding problems. If you have or have had an aneurysm or a tear in a blood vessel wall. If you are looking forward to an operation or if you have an unhealed wound. If while on treatment with this drug, you get symptoms such as confusion, headache, seizures (fits). If you have liver problems.
What should I avoid while taking axitinib? Do not drink grapefruit juice or eat grapefruit. The grapefruit may be responsible for in order to increase the amount of axitinib in blood.
Warnings and precautions: • • • • • •
Inlyta is not for people aged under 18. Its use has not been studied in the children as well as adolescents. Avoid taking this medication with grapefruit or grapefruit juice, as it may increase the chance of adverse reactions. Use of axitinib 5 mg should be avoided during pregnancy. Talk to your doctor prior to taking it if you are pregnant or might become pregnant. Breast-feeding is not recommended during treatment with axitinib 1 mg. If you feel dizziness or feel tired while on this drug, take special care when driving or using machines. If you have been instructed by your healthcare provider that you have an intolerance to some sugars, contact your healthcare team prior to taking axitinib 1 mg.
Interactions: Inform your healthcare provider if you are taking other drugs, including vitamins, prescription and non-prescription and herbal products. Axitinib and some other drugs may interact with each other and cause adverse reactions. Especially inform your healthcare team if you take: • • • •
Dexamethasone (a steroid). Medicine for: tuberculosis (TB), asthma, seizures, bacterial infections (antibiotics), fungal infections (antifungals), HIV (AIDS) or depression. Herbal medicines (such as St. John’s wort). Antacids, such as rabeprazole, which should be avoided 2 hours prior to and 2 hours after taking axitinib.
If you take more Axitinib than you should: If you accidentally consume excess tablets or a higher dose than you require, contact a doctor right away. If possible, show your doctor the pack, or leaflet. If you forget to take Axitinib: Consume your upcoming dose at your regular time. Do not consume a couple of doses to make up for the missed or forgotten tablets. If you vomit while taking Axitinib: If you vomit, any additional dose should be avoided. The upcoming prescribed dose should be taken at about the usual time. If you stop taking Axitinib: If you are not able to consume this medication as your healthcare provider recommended or you feel you do not need it anymore, discuss with your healthcare team right away. How should I store Axitinib? Store axitinib in the original package at room temperature between 68°F to 77°F (20°C to 25°C). Avoid using any damaged pack. Never throw away any drug via wastewater or household waste. What is the best Price of axitinib?
In India, the axitinib cost is absolutely reasonable. In order to buy this drug at a best price, always choose the WHO-GDP and ISO certified pharmaceutical wholesaler company.
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