Saturday Onsite Presentation Session 4

Navigating Aging and Illness

Session Chair: Oliver Micke

15:35-16:00

68841 |

Cross-Sectional Association of Physical Activity Levels With Risks of Sarcopenia Among Older Taiwanese Adults

Chi Hsuan Tsai, National Taiwan Normal University, Taiwan

Yung Liao, National Taiwan Normal University, Taiwan

Shao-Hsi Chang, National Taiwan Normal University, Taiwan

Objectives: The updated World Health Organization guidelines in 2020 strongly recommend the optimal physical activity level for older adults. Therefore, the present study aimed to investigate the cross-sectional associations between excessive physical activity level and the risk of sarcopenia in older adults. Methods: A nationwide cross-sectional telephone survey of older adults (≥65 years) was conducted in Taiwan from October 2019 to January 2020. Older adults were interviewed to collect data on their self-reported level of physical activity (measured with the IPAQ-SF), sarcopenia risk (measured with the SARC-F), and sociodemographics. Chi-square test and binary logistic regression models were applied. Results: A total of 1068 older adults were surveyed. Compared with optimal physical activity recommendations in WHO guidelines and after adjusting for potential confounders, older adults with insufficient physical activity level (<150min/week, not meeting physical activity recommendation) were more likely to have a higher risk of sarcopenia (OR: 3.18; CI: 1.63-6.22). In contrast, older adults with excessive physical activity level (≥300 min/week, beyond the physical activity recommendation) were less likely to have a lower risk of sarcopenia (OR: 0.38; CI: 0.19-0.75). Conclusions: The findings of this study highlight that inconsistent with 2020 WHO guidelines, beyond the range of physical activity level (excessive PAL) seems to be more effective for sarcopenia prevention in older adults. It is suggested that future research needs to further explore whether excessive physical activity could contribute to other health benefits.

16:00-16:25

68661

| Association of Weight Loss With Hip Osteoarthritis in Older Community-Dwelling Female Adults

Zubeyir Salis, University of New South Wales, Australia

Li-Yung Lui, California Pacific Medical Center Research Institute, United States

Nancy Lane, University of California at Davis, United States

Kristine Ensrud, University of Minnesota, United States

Amanda Sainsbury, The University of Western Australia, Australia

Objective: Most guidelines recommending weight loss for hip osteoarthritis are based on research on knee osteoarthritis. Prior studies found no association between weight loss and hip osteoarthritis, but no previous studies have targeted older adults. We aimed to determine whether there is any clear benefit of weight loss for hip osteoarthritis in older adults, because weight loss is associated with health risks in older adults. Methods: We used data from white females aged ≥ 65 years from the Study of Osteoporotic Fractures. Our exposure of interest was weight change from baseline to follow up at 8 years. We investigated the following 15 outcomes over the 8 years: total hip replacement (THR); development of hip pain; resolution of hip pain; development of radiographic hip osteoarthritis (RHOA); development of symptomatic RHOA; progression of RHOA; and degeneration of 9 individual structural features of the hip (as visualized by radiography). Generalized estimating equations (clustering of 2 hips per female) were used to investigate the association between exposure and outcomes adjusted for major covariates. Results: There was a total of 11,018 hips from 5509 females. There was no associated benefit of weight loss for any of the 15 outcomes. For example, the odds ratio (95% confidence interval) for THR was 0.98 (0.87 to 1.11) for each 5% weight loss. The results were consistent across subgroups defined by overweight and obese body mass index and intention to lose weight. Conclusion: Our findings suggest no associated benefit of weight loss in older women in reducing the incidence.

16:25-16:50

67518 | Based on Technology Acceptance Model of “Teachable Moment” for the Elderly Under the Risk of Epidemic Diseases Empirical Research in Respect

Yi-Hui Liu, National Taichung University of Science and Technology, Taiwan

Jing-Wei Liu, National Taiwan University of Sport, Taiwan

This study aims to examine the impact of the COVID-19 epidemic on the use of technology in elderly and long-term care institutions. The widespread use of mobile devices such as cell phones during the epidemic has led to an increase in distance learning and video greetings, promoting the use of hybrid learning in this field. The study will focus on elderly learning centers, community care bases, and daycare centers, and will use a hierarchical clustering sampling method with a causal path model and questionnaire survey to gather data from 150 samples. The study aims to answer the following questions: (1) How have the elderly persons' technology habits changed due to the risk of the epidemic, and what are the influences of "technology acceptance mode" on their "blended learning activities" and "digital health literacy", (2) What is the technology acceptance mode of institution managers and their workload performance before and after the courses were stopped due to the epidemic, and what is the impact of hybrid learning on the satisfaction of elderly persons. The study will also provide effective coping strategies for long-term care and elderly institutions during epidemics or other similar crises in the future.

16:50-17:15

69201 | Cancer Radiotherapy: A Treatment Option in the Very Old (80+)

Oliver Micke, Franziskus Hospital Bielefeld, Germany

There are only very few clinical data regarding radiotherapy (RT) in elderly patients. We present a retrospective study of all patients aged 80 years and older who underwent RT with external beam irradiation in our institution in the years 2020 and 2021. Overall, there were 163 patients treated with 196 courses of RT. The mean age was 84 years (range: 80–99 years). A total of 97 patients (59%) were male. The treatment intent was palliative in 41% and curative in 59%. The primary cancer diagnoses were: prostate 46, lung 18, breast 25, head and neck 10, gastrointestinal 8, hematologic 7, gynecologic 11, skin 18, genitourinary 9, unknown primary 5, central nervous system 6. The patients were able to complete the prescribed therapy in 153 of 196 courses (78%). Treatment breaks during RT were only required in 54 (33%) of Rt courses. RT can be safely administered to an elderly population with both curative and palliative intent with the expectation of completion in more than 80% of patients. The reasons for inability to complete RT as prescribed are multifactorial, but careful patient selection and attention to comorbidity may optimize the outcome.