PHILABUSTER®

The postharvest preservation solution

The Product PHILABUSTER® combines the active ingredients imazalil sulfate and pyrimethanil, two fungicides with different modes of action and a high level of efficacy. The active ingredients show synergistic effects against a variety of pathogens and as a result it offers a high-level control of a broad spectrum of postharvest diseases. The product offers as well a preventive, curative as anti-sporulation activity.

The product contains 200 g/l pyrimethanil and 200 g/l imazalil and is formulated as a Suspension Concentrate (SC).

H H3C

CH 2

CL

N

CH 2

O

CH

CL

N

N

CH

CH 2

CH 3

N N

Application PHILABUSTER® can be used in dip and wash tanks, drenchers, aqueous line spray and in wax line spray systems.

The objective is to obtain an even cover of the fruit surface with a sufficient residue for qualitative long term storage and a good shelf life afterwards.

For optimal use, treat within 24 hours after harvest.

Rate in %

Rate Treatment time (fl. Oz. / 100 gal) (min)

Concentration pyrimethanil (ppm)

Concentration imazalil (ppm)

Dip, wash tanks

0.125% – 0.375%

16-48

1 -2

250-750

250-750

Drencher

0.125% – 0.375%

16-48

1 -2

250-750

250-750

0.25% - 1.00%

32-128

-

500-2000

500-2000

0.5% - 1.5%

64 - 192

-

1000-3000

1000-3000

Aqueous line spray Wax line spray

Dose rates and application methods vary by country depending on the pathogens and disease pressure. Read the label of the product before any use and contact your local service company or a representative of Janssen PMP in case of any doubt.

PHILABUSTER® is PHILABUSTER® 400SC or PHILABUSTER® SC depending on the country specific registrations

Use Recommendations •

For optimal use of the product, it should be applied as soon as possible after harvest but ideally within 24 hours to be able to protect harvest wounds.

•

Always make a premix of PHILABUSTER® by gradually diluting the product 5 times with water under constant stirring. The obtained premix will offer a very stable treatment suspension.

•

Ideally, the treatment water should be stirred all day long.

•

PHILABUSTER® is not compatible with most of the disinfectants specially the one containing chlorine. In case of incompatibility, the concentration of the disinfectant could be an influencing factor.

•

PHILABUSTER® is generally compatible with other fungicides but mixing PHILABUSTER® with other fungicides is only needed in specific cases because of the spectrum and level of efficacy of the product.

•

Residues are also influenced by several factors including treatment time, pH and temperature of the treating solution.

For further information, contact your local service company or a representative of Janssen PMP.

The Mode of Action The biochemical mode of action of the combination product PHILABUSTER® is related to its two active ingredients.

Pyrimethanil is an anilinopyrimidine fungicide (Group 9) that interferes with the secretion of enzymes necessary for infection by several postharvest pathogens, while imazalil sulfate is an that

imidazole inhibits

fungicide sterol

(Group

synthesis

3) thus

affecting cell wall permeability. As a consequence, PHILABUSTER® is a fungicide with preventive, curative and anti-sporulant activity.

The Spectrum of Activity As citrus fruit is stored and/or transported all over the world, a long lasting activity is essential for a good postharvest product in the citrus fruit segment. Fewer products are available to preserve citrus fruit from decay, therefore it is essential that proper management practices are utilized when using the few remaining products.

Diseases Latin name

Diseases Common name

Level of efficacy of PHILABUSTER速

Penicilium italicum

Blue Mold

+++

Penicilium digitatum

Green Mold

+++

Diplodia natalensis

Diplodia / Stem-end rot

++

Alternaria citri

Alternaria / Black rot

++

Colletotrichum gloeosporiodes

Anthracnose

+

Maximum Residue Limits (MRLs) Maximum for are

Residue

pyrimethanil established

Limits and

in

most

(MRLs) Imazalil market

destinations of the world. For more specific information and updates please contact your service company or the FAS online pesticide MRL database at http://www.mrldatabase.com.

PHILABUSTER速 is PHILABUSTER速 400SC or PHILABUSTER速 SC depending on the country specific registrations

Efficacy of PHILABUSTER® PHILABUSTER® is a very effective product which can be applied through a variety of application methods such as dip and drench applications but also the aqueous and wax spray applications. Each of these application methods has its own level of treatment quality which will ultimately influence the effectiveness of the fungicide.

Effectiveness of PHILABUSTER® via aqueous application 100 90 80 70 60 50 40 30 20 10 0

green mold

stem-­‐end rot FUNGAFLOR®

anthracnose

PHILABUSTER®

FUNGAFLOR® is applied at a rate of 500 ppm imazalil PHILABUSTER® is applied at a rate of 500 ppm imazalil + 500 ppm pyrimethanil

Effectiveness of PHILABUSTER® via wax application 100 90 80 70 60 50 40 30 20 10 0

green mold S

green mold R FUNGAFLOR®

blue mold

PHILABUSTER®

FUNGAFLOR® is applied at a rate of 2000 ppm imazalil PHILABUSTER® is applied at a rate of 2000 ppm imazalil + 2000 ppm pyrimethanil S represents a sensitive strain to imazalil, R represents a resistant strain to imazalil

Anti-resistance strategy PHILABUSTER速 has been developped as a tool for anti-resistance management offering two active ingredients with different modes of action against the main pathogens in citrus.

Nevertheless it is advised to use the product in a sustainable way to preserve it on the long term. All products must be applied at full dose rates to limit the risk of resistance. Low residues and under dosing can hasten the development of resistance.

Janssen PMP provides sensitivity monitoring to track any on the resistance development in any of the pack houses.

With this tool, it is possible to pick up, in a very early stage, possible issues before they result in an insufficient control under practical circumstances. Based on the results, timely efforts and adaptations of treatment schemes and sanitation measurements can be made to preserve your fruit.

Please contact your service company for any further support.

PHILABUSTER速 is PHILABUSTER速 400SC or PHILABUSTER速 SC depending on the country specific registrations

Good Management Practices Good management practices include sanitation, both in the orchard and in the packing house. Sanitation is the first line of defense in decay and fungicide resistance management. A poor sanitation program will undo the positive effects of any fungicide management program.

In the orchard •

Remove inoculum sources of orchard-related pathogens.

•

Do not place bins on muddy orchard soil.

In the packinghouse •

Avoid build-up of inoculum in the drench water by adhering strictly to drench water change schedules.

•

Sanitize water systems, packing lines, storage rooms, and bins.

Key use reasons for PHILABUSTER® •

Superior efficacy against green and blue mold decay

•

Long term activity

•

Preventative, curative and antisporulant effect

•

Essential tool for resistance management in the packing house

•

Widespread establishment of MRLs for Imazalil and Pyrimethanil

•

Flexibility of use in aqueous and wax applications

•

Excellent Return on Investment

The postharvest preservation solution PHILABUSTER® 400SC is a trademark of Janssen Pharmaceutica N.V., Belgium The use of our products is subject to the relevant national legislation. For more information on the status of registration and approval in your country of interest, we invite you to contact us.

Turnhoutseweg 30 B-2340 Beerse, Belgium Tel.: +32(0)14/60.60.57 Fax: +32(0)14/60.59.51 © JANSSEN PHARMACEUTICA NV 2012 EPA EST. NO. 074263-DEU-001

www.janssenpmp.com info@janssenpmp.com