NanoMixer: Precision Microfluidic Mixing for mRNA, DNA, and siRNA
Nanoparticle Formulation


In the field of biopharmaceutical research, precise and reproducible mixing is essential for the development of mRNA, DNA, and siRNA delivery systems. The NanoMixer Microfluidic Mixing System offers laboratory-scale, benchtop microfluidic mixing designed to meet the demands of advanced nanoparticle formulation research.
Why NanoMixer Matters
Traditional mixing methods can introduce variability and compromise sensitive formulations NanoMixer overcomes these challenges by operating electrically without compressed air or hydraulic oil, ensuring a stable and sterile environment for handling delicate biological materials Its programmable syringe pumps allow researchers to precisely control flow rates (0–10 mL/min per pump) and mixing ratios, supporting accurate, repeatable experiments
Flexible and Modular Design
The system comes in multiple configurations to meet diverse research needs:
Dual-Pump (NanoMixer): For two-component blending
Triple-Pump (NanoMixer-Triplex): For three-component formulations
Quadruple-Pump (NanoMixer-Quad): For four-component microfluidic mixing
Gastight syringes (1, 2 5, 5, or 10 mL) accommodate flexible sample volumes, while independent PLC-controlled pumps ensure uniform mixing with low dead volume, minimizing waste and maximizing reproducibility
Performance Highlights
Maximum working pressure: 500 psi
Temperature tolerance: up to 80°C
Compact benchtop footprint: 70 × 36 × 30 cm, weighing 20–35 kg
Flush-to-clean design for easy maintenance
CE and RoHS certified Applications
NanoMixer is ideal for:
mRNA, DNA, and siRNA lipid nanoparticle formulations
Liposome and nanoemulsion preparation
Fat emulsions and nanoparticle suspensions
Multi-component formulation development and optimization
Conclusion
For researchers and formulation scientists, Microfluidic NanoMixer provides a reliable, precise, and efficient solution for lab-scale microfluidic mixing. Whether developing lipid nanoparticles for gene delivery or optimizing multi-component formulations, NanoMixer ensures consistent results with minimal variability, accelerating research and innovation in nanomedicine and biopharmaceutical development