Hirshberg Foundation 2013 Summer Newsletter

HIRSHBERG FOUNDATION

FOR PANCREATIC CANCER RESEARCH FOUNDATION NEWSLETTER SUMMER 2013

EVENT RECAPS

MEDICAL UPDATES

FUNDRAISING SUCCESSES

KIDS CAN CURE IN ACTION

Help Carve Out A Cure for Pancreatic Cancer

www.LACancerChallenge.com Sunday, October 27, 2013 2

YOU CAN HOPE OR YOU CAN HELP 速

Benefiting the

REGIS TRATION NOW OPEN !

IN THIS ISSUE: FOUNDATION NEWSLETTER SUMMER 2013 Medical & Research Updates 6 | 2013 Symposium Recap & American Pancreatic Association 8 | Pancreatic Cancer: Surgical Management 9 | Chemotherapeutic Management 10 | Inherited Pancreatic Cancer: Causes and Management 8

11 | Eat Your Veggies: Cancer Prevention Micro to Macro

12 | Psychological Strategies for Managing Well-Being with Pancreatic Cancer 13 | Celebrating Scientific Discoveries

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You Can HELP Funds 14 | Tyrone Buchheim Fund — A Surprise Birthday with an Unexpected Gift 15 | David Barach Fund — In Loving Memory of Uncle Dave 16| James S. Hillgren Memorial Fund — A Dedication to our Great Friend & Colleague at CLG 18

SPOTLIGHT: Kids Can Cure In Action

18 | Dr. Maitra & Teenager Jack Andraka Collaborate 20 |An Impactful 7th Grade Project 21 | 11 Year Old Heats Things Up with a Chili Cook-Off 18

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Hirshberg Training Team

Event Spotlight

22 | Hirshberg Training Team Recap

17 | 1st Annual Gourmet Cupcakes &

23 | Why I Started Running

Champagne Fundraiser

25 | Teaming up with Mom to Run the LA Marathon

25

Tour de Pier Recap 26 | 1st Innuagural Manhattan Beach Tour de Pier 26

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ABOUT THE FOUNDATION

F

ounded in 1997, the Hirshberg Foundation for Pancreatic Cancer Research is a national, nonprofit organization dedicated to advancing pancreatic cancer research, and providing information,

resources and support to pancreatic cancer patients and their families.

DIRECTORS & TRUSTEES Agi Hirshberg, President & Founder Lisa Manheim, Director Jon Hirshberg, Trustee Michael Berliner, Trustee Stephen C. Prince, CPA Michael Scott, ESQ Lisa Fletcher, Trustee

SCIENTIFIC ADVISORY BOARD Vay Liang W. Go, MD, Chair Laszlo G. Boros, MD Murray Korc, MD Laurence J. Miller, MD

HIRSHBERG FOUNDATION FOR PANCREATIC CANCER RESEARCH 2990 S. SEPULVEDA BLVD. , SUITE 300C LOS ANGELES, CA 90064 (310) 473-5121 (P) (310) 473-5107 (F) WWW.PANCREATIC.ORG

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Stephen J. Pandol, MD Howard A. Reber, MD Lee S. Rosen, MD Diane M. Simeone, MD

Photos by: Angela Daves Haley www.adhphotography.com

YOU CAN HOPE OR YOU CAN HELP 速

WELCOME!

E

ach and every day I wake up committed to a single goal—improving the outcome of a pancreatic cancer diagnosis. I am surrounded by

a dedicated and determined team at the foundation office and a world renowned Scientific Advisory Board to steer us towards state of the art research efforts. Since 1997, we have granted millions for research, hundreds of thousands in financial support for patients, and we provide a 24/7 response to guide patients to the most advanced cancer centers, worldwide.

Over the years I have met many families who have become my extended

family through this fight for life. My “foundation family� is in the fight with me, year after year, not running away from this battle. I applaud you and without you, our gains would be non-existent or minimal at best.

As we all know, the greatest gains in scientific discoveries for cancer have been achieved through private funding. Featured in this newsletter are just a few recent examples of how people of all ages are aiding us in our efforts by hosting creative fundraising events to running marathons or simply creating online funds.

I hope you find inspiration in their stories.

Also featured in this newsletter is a recap of our first exclusive Patient and Family Symposium. Held in January of this year, it was a day of hope and amazing progress in all areas of treatment. In the last decade there have been more advances in surgery, oncology, detection, prevention and psychosocial management of pancreatic cancer than in any period since the war against cancer began with the signing of the National Cancer Act in 1971. I can tell you that 16 years ago, when our foundation began this fight, only 2 drugs were available, surgical down-staging was not yet possible, diet and prevention were not emphasized, studies of processed and engineered foods were not on the research radar and most importantly diabetes and obesity were not yet linked to pancreatic cancer. Last but not least, personalized medicine, through genomics, was in infancy stages.

The momentum for change is in place today! Each and every missing link that was not understood in 1997 is being addressed today, thanks to private philanthropy and the subsequent funding that continues to make advances possible. I believe a cancer free life is within our reach.

Enjoy this newsletter, and as always, let us know what you think.

With grateful appreciation for your continuous support and have a great summer,

Agi Hirshberg, President & Founder

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2013 HIRSHBERG SYMPOSIUM RECAP

O

6

n January 26, 2013 we held the 9th Annual

Hines from UCLA who talked about the Surgical

Hirshberg Symposium for Pancreatic Cancer

Management of Pancreatic Cancer, followed by Dr.

Research at the UCLA Faculty Center. The five hour

Teri Brentnall from University of Washington who

event was designed for pancreatic cancer specialists

discussed Early Detection and Genomic Medicine.

to discuss, share and answer questions on Advances

Dr. Lee Rosen then informed our audience about

in Pancreatic Cancer Management. The program

Chemotherapeutic

was exclusively for patients, families, caretakers

Cancer while the Psychosocial Management of the

and those that have been touched by pancreatic

disease was presented by Dr. Kauser Ahmed. The

cancer to receive informed updates in lay-terms

final speaker was Dr. Diane Harris from the Center

from leading doctors and researchers. Because of

for Disease Control and Prevention, who discussed

the quality of our program, about forty physicians

cancer prevention and a healthy diet. After the

and scientists from the medical community also

five speakers there was a question and answer

attended.

session where patients were able to ask our panel

The Symposium began with opening remarks from

questions in a comfortable environment. We ended

Agi Hirshberg, Dr. Vay Liang W. Go, Chief of the

our Symposium with a healthy lunch in the UCLA

Hirshberg Scientific Advisory Board, and A. Eugene

Faculty Center.

Washington, Dean of the UCLA School of Medicine,

There was no cost to attend this event, which was

who spoke briefly about the importance of the

sponsored in part by Genentech and Celgene. Video

partnership between the Hirshberg Foundation

presentations from the Symposium are available to

and UCLA. The first speaker was Dr. O. Joe

view at www.pancreatic.org.

YOU CAN HOPE OR YOU CAN HELP 速

Management

of

Pancreatic

From left: Teresa A. Brentall, MD, Lee Rosen, MD, Agi Hirshberg, O. Joe Hines, MD, Kauser Ahmed, PhD, Vay Liang W. Go, MD, Diane Harris, PhD, MPH

Video presentations from the Symposium are available to view at www.pancreatic.org.

The Hirshberg Symposium is supported by unrestricted educational grants from:

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SYMPOSIUM PRESENTATION PANCREATIC CANCER: SURGICAL MANAGEMENT O. Joe Hines, MD University of California, Los Angeles

S

urgery

for group is focused on four new areas of translational

p a n c r e a t i c research that we think will impact our patients.

cancer

remains First, there is no doubt that the field of pancreatic

the only potential cancer desperately needs a test for early detection. for

cure,

but Drs. David Wong and James Farrell have found

u n f o r t u n a t e l y that the saliva can be used to identify patients with most patients are this disease. A larger trial has now been started in not candidates for order to validate these findings. Secondly, we now operation because know that certain patients and patient families are of

advanced at increased risk for the development of pancreatic

disease. Over the past year there has been renewed cancer. Drs. Enrique Rozengurt and Joe Hines are focus on using chemotherapy before operation in working to determine if the drug Metformin can order to shrink large pancreatic tumors. This allows be used to prevent pancreatic carcinogenesis. Dr. more patients to have their tumor removed that Charles Brunicardi has discovered a new gene previously could not. This advance is important that can promote pancreatic cancer and he is now since the data is clear that removing pancreatic initiating a phase I study in patients with pancreatic cancers that have not spread to other organs cancer to see if targeting this gene is safe in this impacts survival. In addition to this area, our patient population. Finally, Drs. Donahue, Radu, and Czernin are using PET CT imaging to predict which patients will respond to the most commonly used

chemotherapeutic

drug,

Gemcitabine. The concept would be to use other drugs for patients in whom this test suggests gemcitabine resistance. Significant advances in pancreatic cancer laboratories over the past decade are now facilitating translational / patient studies that should have direct impact on patient care.

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SYMPOSIUM PRESENTATION CHEMOTHERAPEUTIC MANAGEMENT

C

urrent pancreatic cancer therapy depends on the

Lee Rosen, MD

stage of the disease: stage 1 - the tumor < 2cm and

University of California, Los Angeles

contained within the pancreas, stage 2 - has grown outside the pancreas, not involving major blood vessels, and may have spread to the local lymph nodes, stage 3 â&#x20AC;&#x201C; the tumor is growing outside the pancreas and has spread to major blood vessels or nerves, stage 4 - has distant metastasis. The treatment options include surgery, radiation therapy, chemotherapy, or combination of all approaches. Dr. Rosen illustrated various case studies to illustrate his point that pancreatic cancer therapy one size does not fit all. He then focused his presentation on the current status of chemotherapy and future goals of personalized therapeutic approaches. Current chemotherapeutic agents are used, including 5-Fluorouracil, Gemcitabine, Oxaliplatin, Cisplatin, Taxanes, Irinotecan, Erlotinib, and several new agents under phase I and phase II

of case studies for various chemotherapeutic

clinical trials. Issues around chemotherapy include

treatment options. Lastly, Dr. Rosen presented the

when to use single agents vs. combinations, using

goal of personalized therapeutic approach based

neoadjuvant therapy with surgery or radiation

on molecular targeting agents and the exciting

therapy, considering a patientâ&#x20AC;&#x2122;s performance status, or

future and preliminary results of various agents

deciding when to use alternative therapy and when to

in different stages of animal experimentations

travel to a different medical center for participation

and in clinical trials and their other use in

in various clinical trials. He highlighted again the use

targeted imaging and diagnosis and prevention.

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SYMPOSIUM PRESENTATION INHERITED PANCREATIC CANCER: CAUSES AND MANAGEMENT Teresa A. Brentnall, MD University of Washington

P

ancreatic cancer is difficult to detect and even ultrasound (EUS) and magnetic resonance imaging harder to treat. At least 10% of pancreatic (MRI), the doctors can identify patients who have

cancer is due to a genetic predisposition. These high- an abnormal appearing pancreas. Such patients, if risk patients who are susceptible to cancer would they are good surgical candidates and under the age be a good group to follow clinically for the earlier of 75, can undergo a surgical procedure to obtain a detection of the diseaseâ&#x20AC;&#x201D;at the pre-cancer stage, tissue sample to make a pathology-based diagnosis when it would be curable. Dr. Teri Brentnall and of pre-cancer. If advanced pre-cancer is present her colleagues at the University of Washington (UW) in the tissue sample, then complete removal of the are working on methods to detect pancreatic cancer diseased pancreas can be considered by the patient before it becomes lethal. The Pancreatic Cancer and the team. This type of surgery is only performed Surveillance Program that she leads is devoted to the in highly selected patients who are at markedly high surveillance and treatment of pancreatic pre-cancer risk of pancreatic cancer. Through this method, we in families who inherit the disease (families who are now able to identify patients who have pancreatic have 2 or more members with pancreatic cancer.) pre-cancer and warrant surgical intervention, to This surveillance program has been ongoing since prevent invasive cancer and cure them of their 1996 and the specialists involved have a great deal of early disease. At present, almost all symptomatic experience taking care of these complicated patients. pancreatic cancer is advanced and incurable when The approach requires the expertise and dedication diagnosed. In hereditary pancreatic cancer we have of doctors who are trained in endoscopy, surgery, shown that pre-cancer or early cancer diagnosed and pathology of the pancreas. Using a combination while asymptomatic is curable. of

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imaging

techniques

including

endoscopic

YOU CAN HOPE OR YOU CAN HELP ÂŽ

SYMPOSIUM PRESENTATION EAT YOUR VEGGIES: CANCER PREVENTION MICRO TO MACRO

D

r. Harrisâ&#x20AC;&#x2122; presentation focused on the role of

Diane Harris, PhD, MPH

fruits and vegetables in cancer prevention

DHHS Centers for Disease Control and Prevention

and highlighted programs and priorities of the

Atlanta, GA

Centers

for

Disease

Control

and

Prevention,

Division of Nutrition, Physical Activity and Obesity.

Epidemiological

and

clinical

investigations

demonstrate that diets rich in fruits and vegetables reduce risk for many chronic diseases, including pancreatic cancer and other types of malignancies, type II diabetes, stroke, heart disease, high blood pressure, arthritis, and excess weight gain. The long time frame for development of pancreatic cancer and other chronic diseases offers a window of opportunity for prevention strategies. Fruits and vegetables contain photochemicals, compounds which are not required for normal functioning of a body, but nevertheless have beneficial effect on health or an active role in prevention or amelioration of disease. Among CDC priorities in nutrition are to impact policies, systems, and environments to increase consumption of fruits and vegetables and decrease consumption of sugar drinks, high-energy density food, and increase physical activity. These approaches have been incorporated in the 2010 Dietary Guidelines for Americans (http://www. cnpp.usda.gov/dietaryguidelines.htm).

Consumer

guidance is offered in MyPlate.gov (http://www. choosemyplate.gov/), which says vegetables and fruits should make up half of the plate. Dr. Harris concluded her presentation on the Federal strategies for increasing fruits and vegetable consumption by reviewing selected strategies, including Farm to School programs, Letâ&#x20AC;&#x2122;s Move Salad Bars to Schools, and the HHS/GSA Health and Sustainability Guidelines for Institutional Food Service.

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SYMPOSIUM PRESENTATION PSYCHOLOGICAL STRATEGIES FOR MANAGING WELL-BEING WITH PANCREATIC CANCER Kauser Ahmed, PhD

L

iving with pancreatic cancer is not a fixed state, but an evolving experience that is marked by both periods of stability

as well as unexpected periods of vulnerability. To navigate these challenges, flexible strategies are called for.

Some stresses are predictable, such as anxieties that arise before a scan or difficult side effect to a new treatment. Others can be unexpected, like hearing a news report about cancer. It is important for patients to find ways of managing these anxiety triggers. For many, these strategies include communication as well as mind/body relaxation.

It is important to communicate with your doctors about difficult side effects so that they can tailor your treatment to you, as a whole person, and help you enjoy the activities that matter most. It can also be helpful to talk to family members about upcoming events.

It is easier for everyone to enjoy precious celebrations when all are clear about the realistic limitations to your energy, mobility, etc. Relaxation strategies such as visualization, breathing and even exercise can help manage acute stress responses and assist you to achieve a more balanced state. The more one practices these, the more consistent the benefit in reducing stress. Lastly, the greatest challenge can be managing the elements that are out of one’s control, and not feeling a sense of responsibility to be “strong” or “positive”. Sometimes the distress of dealing with a cancer diagnosis can create a real physiological diagnosis of depression or anxiety and it is important to treat these by seeking professional care, as one would with any other medical event. Stress during cancer can’t be eliminated but it can be managed; and the vulnerability it highlights can be a reminder of all that is precious in our lives that we can still choose.

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YOU CAN HOPE OR YOU CAN HELP ®

Simms Mann/UCLA Center for Integrative Oncology

PLANS FOR 10 TH ANNUAL SYMPOSIUM CELEBRATING SCIENTIFIC DISCOVERIES

by Vay Liang W. Go, MD Chief of the Hirshberg Scientific Advisory Board

T

he 10th Annual Agi Hirshberg Symposium will be held in conjunction with the annual meeting of the American Pancreatic Association in

Miami from October 30—November 2, 2013. The program will highlight a decade of achievements of the Hirshberg Foundation Seed Grant Program.

All former Seed Grant awardees, both nationally and internationally, will be invited to participate. This group of physicians and scientists have contributed significantly to our current knowledge and advancement in the mechanism of pancreatic cancer development to early diagnosis,

surgical and chemotherapeutic management and psychosocial and prevention strategy of this disease. The Foundation’s Scientific Advisory Board is very pleased and proud of the achievements of the program to date. We look forward to this national celebration and congratulate the Hirshberg Foundation for the success of their research Seed Grant Program.

STAFF UPDATE

M

any of you will recall seeing Allison Miller, our beloved Patient & Family Support Coordinator,

waddling around at this past LA Cancer Challenge with a baby in her belly. Allison became a mom this past January when she delivered a healthy baby boy, Bryan. Named after Allison’s dad Bernie, who died from pancreatic cancer in 1998, we look forward to watching Bryan grow up with his extended Hirshberg Foundation family. Allison has already returned to work part-time and looks forward to catching up with everyone now that she is back from maternity leave.

Allison and Bryan

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YOU CAN H.E.L.P. FUND SPOTLIGHT: TYRONE BUCHHEIM FUND A Surprise Birthday with an Unexpected Gift

By Tatjana Luethi

T

his January, a year after my father-in-law Tyrone passed away from pancreatic cancer,

my husband Mark’s 40th Birthday was quickly approaching. Mark’s mother Meta, sister Debbie, and I wanted to do something to celebrate my husband’s life and honor his father’s memory. So, we set out to plan a surprise birthday party for him and raise funds to donate to The Hirshberg Foundation. This would be our gift to Mark. I wanted to support a foundation near us that was making a difference for patients and families affected by pancreatic cancer.

Mark as a young boy with his father Tyrone

“

The last few months and days were both difficult

in our fundraiser. They stood by us in support of

and beautiful. My sister and I are his legacy. His

research that will help find early detection methods

beautiful grandchildren are his legacy. We are

and new treatment options for families in the future.

the gentle, giving, intelligent, and humorous

We did this as a tribute to Mark’s dad. It hadn’t been

children and adults we are today not in-spite of our

long since Tyrone passed away and I remember

”

experiences but because of them.

my husband’s powerful reflection on his father’s life, the time they spent together, and some of their

Our conspiracy was to keep Mark “busy” with our final memories. Mark wrote, “The last few months friends before his party. As it turned out Mark was and days were both difficult and beautiful. My sister and wasn’t surprised. Invitation websites simply and I are his legacy. His beautiful grandchildren are don’t always work perfectly–oh well, lesson learned! his legacy. We are the gentle, giving, intelligent, and However, by the end of the evening 65 of his close humorous children and adults we are today not infriends and family joined us and had a blast. He was spite of our experiences but because of them.” genuinely touched by the fund we’d created and Planning this unique gift turned into a wonderful appreciative of all the donations in memory of his experience and great collaboration with The dad.

Hirshberg Foundation. Mark’s surprise birthday We’re so grateful to all who generously participated party is a memory that will always stay with us.

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YOU CAN HOPE OR YOU CAN HELP ®

YOU CAN H.E.L.P. FUND SPOTLIGHT: DAVID BARACH FUND In Loving Memory of Uncle Dave

By Sarah Banks

A

n avid runner for most of her life, Lexy Green wanted to do something special to honor the memory of her Uncle

Dave so she signed up for her first half-marathon. Diagnosed with pancreatic cancer in 2012 at 55 years old, David fought the disease for two months. His efforts to remain physically and emotionally strong inspired his nieces Lexy, Christy, and Livy. The three sisters were very close with him; growing up he took them to play dates, sports events, and was an incredibly supportive influence. To his nieces he would always be a spirited, lovable, and memorable man in their lives. It felt only natural to honor him through an experience that would inspire hope. An unforgettable memory as a tribute for an unforgettable man.

Lexy, Christy, and Livy decided to coordinate efforts to fundraise

David Barch & Neice Lexy Green

for pancreatic cancer research while Lexy prepared to run the 2013 Austin Half-Marathon. Christy and Livy helped spearhead fundraising while Lexy trained. The sisters started a H.E.L.P. Fund with the Hirshberg Foundation and began asking friends, family, and their sorority sisters to donate. Their mom stepped in to help fundraise by reaching out to colleagues and loved ones.

Lexy says, “The money my mom, sisters and I raised in his memory, in such a short period of time, is a testament to his character and how many people absolutely adored him.”

David Barach meant the world to his neices and they worked

“

This experience was truly a

journey beyond anything we’ve ever done. It was so meaningful and

overwhelmingly

inspiring,

and something that we plan to keep doing!

”

together to honor his memory. Lexy reflects, “Our Uncle Dave was adored by family, friends, co-workers, and all who came to know him. He really was such an amazing person and his good nature and positive spirit will forever be an inspiration to everyone who knew him.” she added “This experience was truly a journey beyond anything we’ve ever done. It was so meaningful and overwhelmingly inspiring, and something that we plan to keep doing!”

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YOU CAN H.E.L.P. FUND JAMES S. HILLGREN MEMORIAL FUND A Dedication to our Great Friend & Colleague at CLG

By Sarah Banks

J

ames S. Hillgren was a devoted husband, a loving

time to learn, and a time

father, and an engaging leadership coach at The

to serve.” The two people

Continuous Learning Group (CLG). In October of

closest to him at CLG, Steve Jacobs and long-time

2011, Jim lost his 10-month battle with pancreatic

Executive Assistant, Donna Dotson. Spoke fondly

cancer. Throughout his diagnosis he was known

of his calm yet proactive nature. Steve has said

for his positive attitude and for remaining honest

“Jim created a sense of purpose and camaraderie.

& objective about his diagnosis even as the disease

When he spoke people

became more challenging. His CLG business partner

focused more on others than himself. He had a

of 15 years, Steve Jacobs, described him as “a

strong presence and a great sense of humor but he

warrior” as he endured vigorous treatments. In a

encouraged others around him to shine.”

letter written to the company, Steve expressed “we

The company has always seen their motto “When

will miss Jim more than words could ever describe.”

it’s time to make things happen” as a call to action

An executive at CLG, Jim wore many hats as a business

amongst peers and clients alike. Undoubtedly,

partner, a Chief People Officer, Board Director, and

his knowledge, expertise, and caring guidance

leadership coach. One of Jim’s final projects was co-

helped people unleash their true potential. Jim’s

authoring the book “The Behavior Breakthrough”.

real gift was that he had a gentle, quiet approach.

As a special way to honor his memory, co-authors,

People were naturally drawn to him and his innate

partners, and mentees dedicated the book in Jim’s

ability to create calmness where there was chaos.

memory. The company then reached out to the

Throughout his illustrious career, Jim’s thoughtful

Hirshberg Foundation to set up a H.E.L.P. Fund as a

leadership and his inviting, calm style were ever-

special tribute to him. After the book release in May

present in all he did as a CLG senior executive.

2013, CLG will be contributing a portion of the book

He was a dedicated member of the Continuous

royalties towards research and supporting patients

Learning Group family since 1998 and his peers

and families facing pancreatic cancer.

at CLG will remember him as an exceptional and

Jim believed in giving back, it was a code he lived

generous man. Jim Hillgren’s legacy will continue

by. One of Jim’s favorite quotes

through the work of individuals and organizations

was, “There’s a time to earn, a

around the world.

listened, yet he always

A portion of the book royalties for “The Behavior Breakthrough” will be contributed towards research and supporting patients and families facing pancreatic cancer. www.TheBehaviorBreakthrough.com 16

YOU CAN HOPE OR YOU CAN HELP ®

EVENT SPOTLIGHT: 1st Annual Gourmet Cupcakes & Champagne Fundraiser

O

n April 28th, close friends Debbie Ragonig and Kim Colton hosted the 1st Annual Gourmet

Cupcakes & Champagne fundraiser at the Federal Bar in North Hollywood. Only two weeks before Mother’s Day, the timing seemed to align perfectly as Debbie planned an event to honor the memory of her mom. After enduring cancer treatment on and off during her adult life, Debbie’s mom ultimately faced a pancreatic cancer diagnosis which she fought for 6 months.

Debbie Ragonig and Kim Colton and much more. And it didn’t stop there. Over 30 raffle packages decorated the Federal Bar including gift cards to movies, restaurants, activities, getaways and even a Lucky Strike Bowling party. A full

Ten years later, Debbie began a journey of becoming

room was dedicated to eight leading Los Angeles

increasingly pro-active for her own health as well

bakeries including two winners from Season 2 of

as for her kids. After much research on pancreatic

Food Network’s “Cupcake Wars”, Bake You Happy

cancer and ways to help join the fight, Debbie

and Double “D” Cupcakes, who made and donated

recalls reading articles from medical journals and

cupcakes. Joining the line-up of bakeries adding

statistics about the disease. She thought to herself,

decadent cupcakes was, Create Your Own Cake

Cupcakes and Champagne should definitely be a

Bakery, Cup My Cakez, Heavenly Frostings Shoppe,

recipe to help fight against pancreatic cancer and so

The Blooming Bakery, ButterSweet Minis, and

this event was born!

Nothing Bundt Cakes. This class act was topped off

With over 75 people in attendance the fundraiser

with champagne to sip and cheese platters. To say

raised $7,000 in three hours. Guests attending

the least, the amount of sponsors and donations for

received unlimited free cupcake samples, a swag

this event was off the chart!

bag, a raffle ticket and a glass of champagne. Debbie

Kim and Debbie were very happy with how their

and Kim searched, what seemed like, all of Southern

event came together. Kim commented, “We wanted

California for the right bakeries and prizes their

to host our own event to raise money for pancreatic

guests would spend big bucks on. The response to

cancer. The event turned out better than we could

donation requests was amazing! They collected 14

have hoped. It was a lot of work but well worth it.”

silent auction packages including a Napa Valley trip,

I don’t think there was a dry eye in the house when

VIP seats to “The Ellen Show,” deep sea fishing for

Debbie gave her speech and told her story.

two, VIP tickets to the Tonight Show with Jay Leno,

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KIDS CAN CURE IN ACTION: DR. MAITRA & TEENAGER JACK ANDRAKA COLLABORATE Editor’s Note: In 2012, 15 year old Jack Andraka from Maryland became instant news by winning first place at The Intel National Science Fair. He had developed a novel test to detect early stage pancreatic cancer and we began receiving countless calls and emails about this budding scientist in the pancreatic cancer community.

Jack’s mentor, Dr. Anirban Maitra at Johns Hopkins, was a Hirshberg keynote speaker several years ago at the annual American Pancreatic Association’s meeting. Dr. Maitra’s lecture on genomics and clinical applications was brilliant and inspirational, so it was no surprise that he became a mentor to this young scientist. We asked Jack and Dr. Maitra to share their story with us and say a few words about their collaboration.

by Jack Andraka, 15 Year Old Researcher

W

hen I was 14 years old a very close friend

Suddenly it hit me- what if I dispersed antibodies to

of our family died from pancreatic cancer.

a protein over expressed by pancreatic cancer with

I didn’t even know what a pancreas was! I began

single walled carbon nanotubes and dipped strips

to do some research and quickly found out what a

of filter paper to create a sensor. When the ‘cancer

terrible disease it is and discovered that it’s often

protein’ was dropped onto the strip the protein

not diagnosed until much too late. There had to be a

would bind with the antibody and cause a change in

better way. While I continued learning about current

the electrical property of the strip. I could measure

ways of treating cancer I was also working on the

this change with an ohm meter from Home Depot.

effects of nano particles on marine and freshwater

Of course there was a lot more research to do but

organisms. I was fascinated by single walled carbon

finally I had my proposal ready. I searched the

nanotubes- they’re like the superheroes of material

internet for professors who did pancreatic cancer

science!

I smuggled an article about nanotubes

research and sent out emails to about 200 people

into my high school biology class and was reading

and got 199 rejections. I got one interview and it

it while the teacher was telling us about antibodies.

was with Dr. Maitra! I could finally start working

continued...

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YOU CAN HOPE OR YOU CAN HELP ®

in the lab but at first nothing was working. I had so much to learn. I worked after school and on weekends and my school holidays and finally, after 7 months, came up with a strip that worked!

Of course, I thought it could be sold in stores right away but Dr. Maitra patiently explained about all the refinements and trials that still needed to be done. Now I’m talking to several Biotech companies who have the resources for further development and to bring the test to market. If a 15 year old who didn’t even know he had a pancreas could create a sensor to detect cancer using Google and Wikipedia, imagine what you can do!

by Anirban Maitra, MD Johns Hopkins

I

t was truly a privilege to mentor a student as committed as Jack in my laboratory. Remarkably,

when we first met, he was too young to drive. His mother would wait downstairs in the parking lot while Jack completed his experiments. His parents, who did such a fabulous job immersing Jack and his brother in an environment permeated with science and curiosity, deserve a great deal of credit. It’s very unusual for a 15 year old to write an introductory email that contains 30 pages of protocol, complete with supplies, catalog numbers and pitfalls! So, accepting Jack into the laboratory was a no-brainer.

Genius is 99% perspiration and 1% inspiration, and Jack worked very hard during the 7 months he spent in my laboratory prior to the Intel Science Fair. I truly hope Jack is able to inspire the younger generation of this country that science can be cool!

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KIDS CAN CURE IN ACTION: AN IMPACTFUL 7 TH GRADE PROJECT Editor’s Note: Ari Troper, a 7th grade student at Gideon Hausner Jewish Day School, set a goal to raise awareness for pancreatic cancer through his class philanthropy project this year. “Avodah La’Olam” in Hebrew translates into “Helping the World” but for Ari this project also became a way to honor the legacy of his grandma Graciela. Amongst 50 other students in his class selecting various non-profits to support, Ari created a remarkable presentation about the Hirshberg Foundation that would touch his peers, teachers, and family. He made a larger impact than he could have imagined simply by sharing his story and supporting a cause he believes in.

By Ari Troper

M

y grandma was a very sweet person. I cherished all the moments I had with her.

When she was diagnosed, my family was so scared.

But, she continued to do the things she loved, like painting and pottery. She wanted to enjoy life.

However, pancreatic cancer eventually overtook her. Everything came as a rush of emotions to me.

This was a very devastating time for both me and my family. What hurt even more was that we knew there was no way to stop it. I knew I had to help fight this terrible disease. I couldn’t let what happened to my grandma happen to others.

The Avodah La’Olam project has been an amazing experience for me. I learned so much about pancreatic cancer and why it should have more attention directed to it. Through this project I was able to show how dangerous pancreatic cancer is and why people should get involved. I could feel the power of what I was doing. It felt so fulfilling.

I’m so grateful to my parents who supported me and gave me encouragement and my Avodah La’Olam teacher Ora Gittelson-David for guiding me through this learning experience. One of the reasons I wanted to support the Hirshberg Foundation family

20

was because they have been personally touched by pancreatic cancer themselves which makes them even more motivated to find a cure. They helped me understand why we should care so much.

After my presentation, classmates were telling me how much they felt my pain and how much they really wanted to help fund the organization. My teacher let me know how deep my presentation was, and my family beamed with pride. I remember handing out purple pins for pancreatic cancer and for the rest of the day, as I walked through the school, I felt so proud watching person after person wearing one. It just makes you feel good to know you did something. I put my heart and effort into this project for my grandma because I loved her. If this story will motivate other kids to do the same as I did, I want to share it!

YOU CAN HOPE OR YOU CAN HELP ®

KIDS CAN CURE IN ACTION: 11 YEAR OLD HEATS THINGS UP WITH A CHILI COOK-OFF

By Sarah Banks

T

his past November, 11 year old Jaden Del

nine types of chili to taste! He emailed an invitation

Guercio held a chili cook-off in the cul-de-sac

and asked people to spread the word. Over seventy

of his neighborhood in Tarzana, CA to honor his

people attended- both adults and kids ages 3 to 70

Grandpa James. In 2001, Jaden lost his grandpa to

years old. His friends, family, and neighbors came

pancreatic cancer; it was the very same year he was

out to support. His mom and dad helped set up the

born so they never had the chance to meet. Jaden’s

tables and electrical to keep the chili hot. They also

family had actually participated in the LA Cancer

helped him organize all the tastings, as he charged a

Challenge for several years so his father and aunt

small flat fee to sample each chili. Jaden had his very

told him all about the Hirshberg Foundation. Jaden

own table where he collected all of the donations,

set out to raise money to benefit pancreatic cancer

counted all the competition votes, and at the end of

research and bring awareness to his school through

the event he announced the lucky winner.

community service. He began by planning a chili

The prize was a giant engraved silver spoon and

cook-off!

a chili pepper necklace! Jaden’s goal was to raise $200 but by the end of the fundraiser, he’d raised

It was my first time doing “ something like this. It makes me feel good to raise money for a good cause and it means a lot to me and my family.

”

over $730. The chili cook-off was a great success and everyone was very generous. Jaden and his parents plan to do another fundraiser benefiting The Hirshberg Foundation because people loved it so much. After the event, Jaden said, “It was my first time doing something like this. It makes me feel good to raise money for a good cause and it means a lot to

Neighbors, the moms of several friends, and his

me and my family.” His mom, Nicole, added “Jaden

parents all helped make chili for the tastings and

was named after his grandpa. He was a loving and

competition. Once they were ready, there were

kind man and would’ve been so proud.”

WWW.PANCREATIC.ORG

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HIRSHBERG TRAINING TEAM 2013 RECAP

By Lisa Manheim

I

n the twelve year history of the Hirshberg Training Team, there have been many memorable moments shared by our teammates. From the moose-

lined course in Alaska in 2003 to the torrential downpour at the LA Marathon in 2011, the stories told are memorable. But what stands out most from the 2013 team that participated in the 28th Asics Los Angeles Marathon was the connection they all made with each other during their training.

Haley Burns, a first-time marathoner recalled the experience. “I think one of my favorite parts of this whole experience was getting to know the people I was

running with. We spent many, many hours running together. Training for and running a marathon together really did create a unique bond between all of us. It felt great to be doing that for a good cause.”

Haley was a part of one of our largest teams to date, the 42 members spent months training for either the 26.2 mile race or the 13.1 mile relay at our Marina del Rey or Pasadena meeting spots. In addition to training, they were actively fundraising to meet their commitment of raising at least $1,000 each for pancreatic cancer research. With experienced guidance from our coaches at Club 26.2, every member of our team crossed the finish line. More importantly, together they raised more than $58,000, bringing our twelve year total to close to a half million dollars raised.

While our team was out running the course, the Hirshberg Foundation was back at Mile 21 hosting the Purple People Party Cheer Station. Once again our enthusiastic supporters, waving purple cowbells and purple pompoms, provided a boost of energy to all of the race participants.

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YOU CAN HOPE OR YOU CAN HELP ®

HIRSHBERG TRAINING TEAM WHY I STARTED RUNNING

By Jonathan Moerschel

I

came

to

seemed like a great idea. It was the first time I came

the

across any organization that was dedicated solely to

and

pancreatic cancer research. At the 2010 LA Cancer

of

Challenge, I ran my first ever 5k, and without

pancreatic cancer

any shoes. It was the longest distance I had ever

when

first

run in my life. It was an unexpectedly emotional

wife, Eugenie, lost

experience for me as I thought about why I was

her

brave

battle

running the 5k and raising money for the Hirshberg

with

the

disease

Foundation. It felt really good to finally be able to do

understand

devastating tragic

effects my

in 2003. She was a

something to help in the fight against cancer.

wonderful pianist,

I was so impressed by the event and how well

and was finishing

organized it was. I could tell that there were so

up her Doctorate of Music Arts degree at USC. She

many others that could understand what I had been

was my best friend and my musical partner. We

through, which was both sad and comforting. It

were married only 10 months. She was 34 years

was sad because I was surrounded by people who,

old, had undergone 5 major surgeries and had been

unfortunately, had experience with pancreatic

fighting pancreatic cancer for 5 years. I was angry

cancer. However, it was comforting to see that so

at the disease and angry that there wasn’t more that

many people had come out to support each other,

could be done in the way of treatment. I remember

to raise awareness about this disease, and to help

deciding that, one day, I wanted to be able to do

raise money for much-needed research. Little did I

something to help in the fight against cancer.

know that running that 5k back in 2010 would lead

Jumping ahead seven years, I had made a decision

me to do something I vowed I would never do: run

to start running again after a 12-year hiatus due

a marathon.

to chronic injuries. I had read about barefoot

I began training for the 2012 LA Marathon in

running, and how many people have overcome

October of 2011. I had been running barefoot for

injuries and were running pain-free. Somehow,

about a year and a half, and still hadn’t run more

this concept was fascinating to me, even as a self-

than 4 miles. After our first training run, I realized

described germaphobe. About six months into

first that I had a lot of work to do before I was ready

my experimental barefoot running phase (yes,

to run a marathon, but I also realized I was getting

running without shoes of any kind), I came across

involved with a really great group of people. We

the Hirshberg Foundation’s LA Cancer Challenge 5k

had such great support and encouragement from

on the internet. I knew right away that I had to get

everyone at Hirshberg and from our running

involved with the Foundation, and running the 5k

coaches Robert, Euri and Jack. We all had our ups

continued...

WWW.PANCREATIC.ORG

23

and downs with training, but we supported each

future of those that are

other and all finished our first marathon that year.

fighting cancer.

I decided by 7pm after that first marathon, that I

I’m

needed to run it again the next year. So, on my 34th

what it is about running

birthday this year, I ran my second marathon.

a marathon that I like,

Running the marathon was a tremendous experience

but I know running the

for me, both physically and mentally. My emotions

marathon for pancreatic

were a roller-coaster of a ride, but every time I felt

cancer

tired or sore, I reminded myself why I was doing it,

experience real purpose

and I managed to push through the discomfort. The

for me. I know that while

outpouring of support from both volunteers and the

I am sore and tired, it is

public who lined the streets really helped keep my

a small sacrifice if I can help make a difference for

spirits up. Coming up to the Hirshberg Foundation’s

someone in the future who will live longer after

Purple Cheer Station at Mile 21 with dozens of

being diagnosed with pancreatic cancer. I am so

cheering supporters all in their purple clothes was

very proud to have been a member of the Hirshberg

an extraordinary experience that brought tears to

Training Team and run the LA Marathon the last

my eyes. That moment was a big reminder of my

two years in memory of Eugenie, and in support of

loss back in 2003, but also a beacon of hope for the

pancreatic cancer research.

not

exactly

gives

sure

the

LET’S CROSS THE FINISH LINE

TOGETHER Run the L.A. Marathon (or 2-person marathon relay) with us and we will help you cross the finish line with our personalized training program.

Every step you take towards the finish line helps us cure pancreatic cancer.

TRAINING STARTS SATURDAY, OCT 5, 2013

REGISTER AT:

www.HirshbergTrainingTeam.com 24

YOU CAN HOPE OR YOU CAN HELP ®

HIRSHBERG TRAINING TEAM TEAMING UP WITH MOM TO RUN THE LA MARATHON

By Nicole Walsh

M

y dad is the kind of person who takes care

for the marathon,

of his family and friends first. On July 23,

I knew just how

2012 he was diagnosed with metastatic pancreatic

much

adenocarcinoma and started treatment three weeks

to him. Training

later. I am currently studying at UCLA and was

for the marathon

feeling a little helpless not being able to live full time

made

with him in Massachusetts. I began searching for

connected to what

local pancreatic cancer charities to support. I found

my dad was going

the Hirshberg Foundation and realized their lab was

through.

I

was

in the same building as the lab I currently work in.

amazed

by

how

I saw the Hirshberg Training Team (HTT) and asked

much I was able to

my mom to do the LA Marathon charity relay with

surpass my fundraising goal. The support from my

me. My mom, Maria, is the person who got me

friends, co-workers, and my dad’s co-workers was

into running. In 2010 I completed my first half-

wonderful. It really drives home how much my dad

marathon, so I thought it would be something we

means to the people he interacts with.

could do together. Even though she lives across the

The marathon and my training with HTT was

country, we could show support for our friends and

amazing. I met some really wonderful people and

family affected by cancer. I was very appreciative

made great running friends who I still run with.

that my mom was able and willing to do this with

Our coaches with Club 26.2 did a fantastic job at

me, especially since she was across the country.

the Saturday morning runs and helped my mom

While I know that she has her own reasons for

through her remote training. It was great to meet

participating, I was touched that she would commit

everyone who is a part of the Hirshberg Foundation.

to the training, fundraising, and all-around effort

They welcomed my mom and I like we were family.

of a half-marathon in California. She knew it was

Both of my parents had a great time on marathon

important for me and her participation meant the

weekend. They were both excited to meet the

world to me.

Foundation and happy to know I have an amazing

It was interesting training as a team, even though we

support network here in LA. The whole experience

lived in different states. I had the benefit of training

is one that I will never forget. After the race my dad

with the HTT most weeks while she had to motivate

told me that he couldn’t have been prouder of me.

herself through her training. My dad didn’t say much

I couldn’t thank my mom enough, not just because

about my mom and I teaming up for this project

she ran with me, but for all of the support she has

when I initially told him. When he bought plane

given me through this difficult time. We are looking

tickets and booked a hotel room to be in LA with us

forward to doing the relay again next year!

it

meant

me

WWW.PANCREATIC.ORG

feel

25

TOUR DE PIER INAUGURAL TOUR DE PIER A HUGE SUCCESS

J

on Hirshberg, who started the first LA Cancer Challenge after the loss of his father Ron in 1997, came across the idea of doing a spin bike

fundraiser after learning about an event that raised over $3 million in one day at cycling studios across the country. Jon approached his friend and long-time cycling enthusiast, Heath Gregory, about the idea of putting on a one-day event in their hometown of Manhattan Beach, CA. Coincidentally, Heath had participated in a similar event put on by Livestrong in Barcelona during the 2009 Tour de France and vividly remembered the spectacle of hundreds of riders moving in unison all for a common cause. His response was, “I’m all in.” With the Foundation on board to produce the event and a team of board members eager to participate, planning for the Tour de Pier began.

After months of preparation, the Inaugural Tour de Pier was held this past May at the iconic Manhattan Beach Pier. The non-competitive fourhour event was broken up into four 50-minute rides formatted like an indoor cycling class. Each ride was led by different local indoor cycling instructors from Spectrum and FitOn Studios. Olympic cyclist Tony Cruz, gold medal volleyball winner Eric Fonoimoana, USPRO Criterium champion Rahsaan Bahati, gold medal water polo player Heather Petri, and NFL quarterback Matt Leinart got into the spin and rode with the hundreds of participating cyclists. The sold out Health Expo will include 30+ companies focused on food, products and services surrounding the idea of living a healthy lifestyle. Sponsors include Neutrogena, Skechers,

continued...

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YOU CAN HOPE OR YOU CAN HELP ®

Wells Fargo, Aquahydrate amongst others.

The interactive Kids Zone included an obstacle course, pitching machine, bouncy, bike raffle and an autograph booth with all of our celebrity riders on hand to sign â&#x20AC;&#x153;Hero Cardsâ&#x20AC;? for the kids.

The community spin charity event raised well over $330,000 for the Hirshberg Foundation, as well as their charity partners The

LiveSTRONG

Foundation,

Cancer

Support Community and The Friendship Circle of the South Bay. Plans are already in place for the 2nd Annual Tour de Pier, to be held on May 18, 2014. For more information please visit www.TourdePier.com.

WWW.PANCREATIC.ORG

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HIRSHBERG FOUNDATION FOR PANCREATIC CANCER RESEARCH

2990 S. SEPULVEDA BLVD. SUITE 300C • LOS ANGELES, CA 90064 (310) 473-5121 • (310) 473-5107 (FAX) • WWW.PANCREATIC.ORG

NON-PROFIT ORG U.S. POSTAGE PAID LOS ANGELES, CA PERMIT NO. 548

STAY CONNECTED

Facebook.com/HirshbergFoundation

Facebook.com/LACancerChallenge

Facebook.com/HirshbergTrainingTeam

Facebook.com/TourdePier