Yi Fan Chen

SCIENTIFIC ADVISORY BOARD INVESTMENT ADVISORY BOARD

THERAPEUTICS DEVELOPMENT CENTER TEAM HARRINGTON TEAM

David Ginsburg, MD William G. Kaelin Jr., MD Barbara B. Kahn, MD Andrew Marks, MD Solomon Snyder, MD, D.Phil., DSc. Michael Welsh, MD Doug R. Lowy, MD (Government Liaison)

Emeritus

Irwin Fridovich, PhD (Deceased) Beth Levine, MD (Deceased) Charles Sawyers, MD June Almenoff, MD, PhD Stephen Burley, MD, D.Phil Nancy Chang, PhD Peter Grebow, PhD Graeme Martin, PhD John Rice, PhD Jonathan Stamler, MD Jesse Treu, PhD

FOR A COMPLETE LISTING OF ADVISORS AND PROJECT MANAGERS, VISIT: HarringtonDiscovery.org/TDC

FOR A COMPLETE LISTING OF HARRINGTON DISCOVERY INSTITUTE TEAM MEMBERS, VISIT: HarringtonDiscovery.org/Team

DISCOVERY AND FUNDING PARTNERS

Individual Philanthropic Contributors The Harrington Family

WE CURE DISEASES

BELIEVERS MAKING AN IMPACT

Longtime UH Supporters Fund New Treatments for Alzheimer’s

Linda and Les Vinney committed $1.25 million to establish the Linda and Les Vinney Scholar Program in Alzheimer’s Disease at Harrington Discovery Institute’s Center for Brain Health Medicines, which will support new treatments for patients. The gift also creates the Linda and Les Vinney Acceleration Awards, which will assist the Vinney Scholars with their research.

A Family Builds Community in its Pursuit of a Cure for FBXO11

Rusty Cooper, Senior Vice President at Morgan Stanley, and his family have much needed hope to help their 7-year old grandson who lives with an ultra-rare disease caused by a mutation of the FBXO11 gene. Through the Oxford-Harrington Rare Disease Centre and Morgan Stanley GIFT Cures powered by Harrington Discovery Institute, they are helping to raise awareness and create a community of families supporting the advancement of novel treatments for rare and ultra-rare diseases.

A Visionary Supports the Future of Medicine and International Collaboration

A $1 million gift from the late Norman Wain, a pillar in the Cleveland community, helped support Harrington Discovery Institute’s entrepreneurial pursuit of drug development collaborations around the world. When the Oxford-Harrington Rare Disease Centre was established in 2019, the gift funded critical start-up needs, including transatlantic travel, to support the successful partnership between the University of Oxford and Harrington Discovery Institute.

500

TREATMENTS EXIST FOR 10,000+

DISEASES

10M

PEOPLE WORLDWIDE ARE LIVING WITH PARKINSON’S DISEASE

12.7M

AMERICANS AGED 65 AND OLDER ARE PROJECTED TO HAVE ALZHEIMER’S DISEASE BY 2050

Only 5%

OF THE 7,000 IDENTIFIED RARE DISEASES HAVE TREATMENTS