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Estrogen Deprivation and Female Hormone Replacement Therapy

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Estrogen Deprivation and Female Hormone Replacement Therapy

Dr. Steven R. Goldstein MD, 212-717-5554,314 East 34th Street, 5th Floor, New York, NY 10016


Dr. Steven R. Goldstein

Dr. Steven R. Goldstein MD is one of the nation’s top gynecologists and an expert on female hormone replacement therapy.

Dr. Steven R. Goldstein MD, 212-717-5554,314 East 34th Street, 5th Floor, New York, NY 10016


Women in their post-reproductive state make many contributions to their families, to our communities, and society in general. However, as they age there are very real medical issues that accompany estrogen deprivation after there is no more ovarian function (the medical definition of menopause). There are very real consequences medically of the lack of estrogen production that menopause brings.

Dr. Steven R. Goldstein MD, 212-717-5554,314 East 34th Street, 5th Floor, New York, NY 10016


Many women are aware of the symptoms of hot flashes and night sweats, the most common of the menopausal transition. There is also a loss of bone mass, which occurs quite rapidly, and osteoporotic fractures are a significant medical issue as the population ages more and more. Joint pains are also common. There are also serious changes in the vagina as a result of a lack of estrogen. A change in the normal bacteria causes diminished production of lactic acid and thus the pH will change dramatically, as does the cell count. This leads to dryness and lack of normal lubrication which, in patients who are sexually active, can result in severe discomfort.

Dr. Steven R. Goldstein MD, 212-717-5554,314 East 34th Street, 5th Floor, New York, NY 10016


Menopause, with its lack of estrogen, on average causes an increase of 15 20% in total cholesterol and LDL cholesterol (the bad cholesterol). In addition, estrogen helps promote lean body mass and after menopause women tend to accumulate more fat centrally (that old “midriff bulge”). So, it is quite clear that estrogen deprivation has an effect on a variety of organ systems especially as women are living longer and longer. As the best hormone specialist in NYC, Dr. Goldstein is aware of new approaches to replacing estrogen without the use of progesterone involving combining the estrogen Premarin with a different category of the drug than progesterone. That category is SERM (selective estrogen receptor modulator) used in female hormone replacement therapy. The pros and cons of replacing estrogen need to be individualized and discussed on a case-by-case basis.

Dr. Steven R. Goldstein MD, 212-717-5554,314 East 34th Street, 5th Floor, New York, NY 10016


Dr. Steven R. Goldstein MD is an expert on menopause and female hormone replacement therapy. He is the co-author of the book “The Estrogen Alternative” and is a Certified Menopause Practitioner by the North American Menopause Society and the Recipient of the Thomas A. Clarkson award for many outstanding contributions to menopause-related clinical or basic science research. Dr. Goldstein, the best hormone specialist in NYC, is a Professor of Obstetrics and Gynecology, New York University School of Medicine and a Director of Gynecologic Ultrasound, NYU Langone Medical Center. To learn more about Dr. Goldstein or to make an appointment, visit his website at www.goldsteinmd.com Dr. Steven R. Goldstein MD, 212-717-5554,314 East 34th Street, 5th Floor, New York, NY 10016


Dr. Steven R. Goldstein MD, 212-717-5554,314 East 34th Street, 5th Floor, New York, NY 10016


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