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At First International Bank &Trust, living first isn’tjustatagline or wishfulthinking .It’s howweintentionally approachlifeand work ever yday,and have been formorethan 10 0 years. We’renot just co -workers ,and you’re notjustclients;weare family.Thankyou to ouremployees fortheir commitmenttoexcellence, and to ourcustomersfor inspiringus to beourbest.

At First International Bank &Trust, living first isn’ tjustatagline or wishfulthinking .It’s howweintentionally approachlifeand work ever yday,and have been formorethan 10 0 years. We’renot just co -workers ,and you’re notjustclients;weare family.Thankyou to ouremploye es fortheir commitmenttoexcelle nce, and to ourcustom ersfor inspiringus to beourbest.

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September 2021

VOL 22 ISSUE 9 continued From page 52

“Their commitment to the center made our proposal stand out from the others,” Perumal said.

The research team includes 11 SDSU faculty members from three departments as well as the university’s Office of Technology Transfer and Commercialization and two South Dakota School of Mines and Technology researchers. Eight private-sector partners, including Avera Cancer Institute and Vance Thompson Vision, are also involved in the center.

The center will focus on one or more of the 3D’s-modifying the existing drugs to optimize their biological and delivery properties, identifying new molecular targets for existing drugs and/or developing new formulations and delivery systems for existing drugs.

In addition to advancing existing pharmaceutical technologies at SDSU and South Dakota Mines, the 3D center will use a collaborative framework to create intellectual property through interdisciplinary projects and to foster an entrepreneurial mindset to strengthen the state’s biomedical and pharmaceutical workforce. The research will address diseases affecting human and animal health.

The 3D Center is one of three projects to receive RCC funding through the Governor’s Center Program, which provides seed funding to support applied research and development centers involving South Dakota universities, businesses and private sector research organizations. The RCC seeks to increase research and development that will make an economic impact through technology commercialization and the development of research-based industry clusters.

Repurposing saves time, money

Repurposing drugs that have already been FDA-approved can shorten the timeline and decrease the costs of bringing new treatments to market, Perumal said.

“An estimated 40% of drugs fail during development because the biological and delivery properties of the compounds are not optimal. It works on cells in a culture dish, but to be absorbed in the human body, it must be water-soluble. Or it may have worked well in the animal studies, but animals and humans metabolize drugs differently,” he continued.

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