FALL Neurosurgery News - EXTERNAL

HEADlines TIMELY NEWS FROM THE DEPARTMENT OF NEUROSURGERY

Fall 2020

HEADlines TIMELY NEWS FROM THE DEPARTMENT OF NEUROSURGERY

Fall 2020 WELCOME FROM DR. KEVIN LILLEHEI, CHAIR OF NEUROSURGERY:

Neurosurgery at the University of Colorado has entered an exciting time in its growth and in its ability to offer cutting edge technology to the care of patients in our community with neurologic disorders. The pace of discovery and innovation in the neurosciences has exploded and the Department of Neurosurgery has positioned itself to be a major player in this arena. With a dedicated faculty of clinicians and researchers, which has quadrupling in the last decade, our ability to offer cutting edge technology and innovation to ourcommunity has skyrocketed.

For all these reasons, we feel it is important to pass this knowledge on to our community partners and to keep them up to date on the developments occurring within the department and within the broader field of the neurosciences. Today, you are receiving the first edition of “HEADlines”, an ongoing series of newsletters designed to keep you informed concerning this very important area of medicine. You, in particular, are receiving this because of your known interest in the neurosciences; either as a patient, a relative of someone who has suffered from a neurologic disorder, or your engagement in the community helping to raise the awareness of neurologic disease. Please know that there is an “unsubscribe” feature at the bottom of this newletter and if you do NOT want to receive this, just unsubscribe.

No problem. Although we will miss you!

The newsletter, “HEADlines”, will be published on a regular basis throughout the year and feature articles on the newest innovations in neurosurgery, patient stories, community events, faculty accomplishments and other things important to the neuroscience community.

We hope you will share this newsletter with family and friends, pass on the word, and help us become a “household name” across the region. There are so many exciting developments going on, we hope this newsletter will help to get the word out!

Welcome to the CU Neurosurgery Department and we are grateful that you are a part of our family.

Thank you for becoming part of this exciting journey with us. Stay tuned for more, pass on the word, and we love the feedback!

Kevin O. Lillehei Professor & Ogsbury-Kindt Chair Department of Neurosurgery

MEET OUR FACULTY & ALL OUR SPECIALTIES NEUROCRITICAL CARE: Jason Weedman, MD One of our newest faculty, Dr. Weedman comes to us from Kaiser and is interested in neuro critical care.

Link: https://www.cudoctors.com/Find_A_Doctor/ Profile/30561

Robert Neumann, MD Interested in neurological and neurosurgical critical care, hemorrhagic and ischemic stroke outcomes, brain tissue oxygenation, cerebral perfusion monitoring and evoked cerebral magnetic fields.

Link: https://www.cudoctors.com/Find_A_Doctor/ Profile/5805

David Case, MD Interested in endovascular surgery and neuro critical care.

Link: https://www.cudoctors.com/Find_A_Doctor/ Profile/23297 To Schedule, call 720.848.7253.

Luis Cava, MD Interested in stroke, traumatic and acquired brain injuries and critical care.

Link: https://www.cudoctors.com/Find_A_Doctor/ Profile/21545

NEUROVASCULAR & STROKE CARE

Robert Breeze, MD Part of the team that performed the first American fetal cell transplant for Parkinson’s Disease, Dr. Breeze specializes in cerebral aneurysm surgery, vascular lesions and malformations, and surgical management of brain tumors.

Link: https://www.cudoctors.com/Find_A_Doctor/ Profile/16802 To Schedule, call 720.848.7196.

Joshua Seinfeld, MD Interests include endovascular and surgical treatment of cerebrovascular disorders such as aneurysms, arteriovenous malformations and fistulae, cavernous malformations, Moyamoya disease, carotid artery disease and stroke.

Link: https://www.cudoctors.com/Find_A_Doctor/ Profile/3148 To Schedule, call 720.848.7253.

Christopher Roark, MD Interests include the full spectrum of cerebrovascular disease. This includes, but is not limited to, ischemic stroke, intra- and extra-cranial stenosis, cerebral aneurysms, and vascular malformations.

Link: https://www.cudoctors.com/Find_A_Doctor/ Profile/24126 To Schedule, call 720.848.7253.

Zachary Folzenlogen, MD A recent fellow with us, we are excited to have Dr. Folzenlogen join the faculty. Although he specializes in endovascular and stroke care, he will also be taking general neurosurgery cases at Highlands Ranch Hospital.

Link: https://www.cudoctors.com/Find_A_Doctor/ Profile/30348 To Schedule, call 303.724.9557.

MEET OUR FACULTY & ALL OUR SPECIALTIES PEDIATRIC NEUROSURGERY Michael Handler, MD Chair of the Neurosurgery Department at Children’s Hospital of Colorado, Dr. Handler specializes in Pediatric Neurosurgery, Congenital Malformations, Brain Tumors, Epilepsy Surgery and Neuro-endoscopy.

Link: https://www.cudoctors.com/Find_A_Doctor/ Profile/689

Brent O’Neill, MD Clinical interests include all pediatric-neurosurgery conditions with a particular focus on pediatric epilepsy surgery, spina bifida (in particular, fetal surgery for myelomeningocele), and hydrocephalus.

Link: https://www.cudoctors.com/Find_A_Doctor/ Profile/16197

Todd Hankinson, MD Interests include brain and spine tumors in children that may require surgery. Dr. Hankinson facilitates shared discussions with patients and parents to work toward comfortable decisions in often very frightening and difficult situations.

Link: https://www.cudoctors.com/Find_A_Doctor/ Profile/15838

Corbett Wilkinson, MD Pediatric Neurosurgery, Craniosynostosis, spasticity (selective dorsal rhizotomy & baclofen pumps), moyamoya disease, congenital malformations of the brain, spinal cord, skull, and spine Link: https://www.cudoctors.com/Find_A_Doctor/ Profile/3342

Allison Alexander, MD Specializing in the surgical treatment of epilepsy; craniosynostosis; hydrocephalus and shunts; Chiari malformations; tethered cords and general pediatric neurosurgery.

Link: https://www.cudoctors.com/Find_A_Doctor/ Profile/26849

FUNCTIONAL NEUROSURGERY / MOVEMENT DISORDERS / EPILEPSY Steve Ojemann, MD Specializing in surgical treatment of movement disorders, and chronic pain disorders, epilepsy surgery, functional and stereotactic radiosurgery.

Link: https://www.cudoctors.com/Find_A_Doctor/Profile/16415 To Schedule, call 720.848.7406.

Daniel Kramer, MD Clinical interests in surgical treatments for movement disorders, epilepsy, and facial pain. Resections for epilepsy, laser therapy, responsive neural stimulators, MR-guided focused ultrasound treatments, new applications for deep brain stimulation, and microvascular decompressions for disorders like trigeminal neuralgia.

Link: https://www.cudoctors.com/Find_A_Doctor/Profile/32854 To Schedule, call 720.848.7406.

BRAIN TUMORS, NEURO-ONCOLOGY, SKULL BASE SURGERY, PITUITARY TUMORS Kevin Lillehei, MD Chair of the Neurosurgery department, specializing in Neuro-oncology and treating tumors including pituitary tumors, benign and malignant gliomas, spinal cord tumors, acoustic neuromas, complex skull base lesions and peripheral nerve injuries.

Link: https://www.cudoctors.com/Find_A_Doctor/Profile/9315 To Schedule, call 720.848.3446.

D. Ryan Ormond, MD Specializing in brain tumors, skull base tumors, minimally invasive endoscopic cranial procedures, meningiomas, acoustic neuromas, colloid cysts, pituitary tumors, general neurosurgery Link: https://www.cudoctors.com/Find_A_Doctor/Profile/22414 To Schedule, call 720.848.7204.

A Samy Youssef, MD Specializing in complex brain tumors, skull base tumors, Minimally Invasive Endoscopic Cranial Procedures, Meningiomas, Acoustic Neuromas, Pituitary tumors, Trigeminal Neuralgia, Chiari Malformation Link: https://www.cudoctors.com/Find_A_Doctor/Profile/22410 To Schedule, call 720.848.7199.

SPINE DISORDERS & NEUROSURGICAL SPINE Jens-Peter Witt, MD Director of the neuro spine program, specializing in treatment of complex spine disorders, complex spinal instrumentation and minimally invasive procedures.

Link: https://www.cudoctors.com/Find_A_Doctor/Profile/2774 To Schedule, call 720.848.9343.

Michael Finn, MD Specializing in the surgical treatment of spinal disorders and the diagnosis and management of spinal pathologies. Also interested in the treatment of trauma, spinal tumors, deformities, and degenerative disease processes affecting the cervical, thoracic and lumbar spine.

Link: https://www.cudoctors.com/Find_A_Doctor/Profile/17475 To Schedule, call 720.848.9343.

Peter Lennarson, MD Specializing in degenerative and traumatic spinal disorders--from the base of the skull down to the neck and back as well as the tail bone and sacroiliac joints. Cranio-vertebral junction disorders. (Arnold) Chiari Malformation.

Carpal tunnel syndrome and Ulnar neuropathy. Minimal Access / minimally invasive surgical techniques.

Link: https://www.cudoctors.com/Find_A_Doctor/Profile/29478 To Schedule, call 720.848.9343.

Bradley Duhon, MD Primarily covering Highlands Ranch Hospital and the south metro area, Dr. Duhon specializes in minimally-invasive spinal surgery, motion preserving spinal surgery (including cervical & lumbar artificial discs), and SI joint dysfunction.

Link: https://www.cudoctors.com/Find_A_Doctor/Profile/21416 To Schedule, call 720.848.9557.

Kerry Brega, MD Heading up our robust residency program, Dr. Brega also covers the Veteran’s Administration Hospital at Anschutz and specializes in spine, general neurosurgery, stroke, neurotrauma and critical care.

Link: https://www.cudoctors.com/ Find_A_Doctor/Profile/12770 D. Mark Melton, MD Dr. Melton is primarily serving the Veteran’s Hospital at Anschutz, covering spine and general neurosurgery.

Link: https://www.cudoctors.com/ Find_A_Doctor/Profile/26879 Angela Downes, MD Specializing in spine, Dr. Downes covers procedures at both the VA and UCHospital, and also does general neurosurgery.

Link: https://www.cudoctors.com/ Find_A_Doctor/Profile/23298 To Schedule, call 720.848.7831.

MEET OUR FACULTY & ALL OUR SPECIALTIES NEURO TRAUMA, TRAUMATIC BRAIN & SPINAL CORD INJURY, CONCUSSION Wayne Gluf, MD Dr. Gluf is the Director of Neurosurgical Trauma, and has spent most of his career in the United States Navy, serving onboard ships as a Special Operations Officer in Explosive Ordinance Disposal (navy diver). He specializes in complex spine with a strong interest in neurotrauma.

Link: https://www.cudoctors.com/Find_A_Doctor/ Profile/28579 To Schedule, call 720.848.9343.

Kathryn Beauchamp, MD Serving as the Chief of Neurosurgery at Denver Health Medical Center, the areas leading trauma hospital, Dr. Beauchamp specializes in complex spine and neurotrauma, with a special interest in concussion and traumatic brain injuries.

Link: https://www.cudoctors.com/Find_A_Doctor/Profile/9933 Muhammed Riaz, MD Serving at Denver Health Medical Center, Dr. Riaz specializes in pediatric brain tumors, congenital spinal anomalies, Selective dorsal root rhizomes, Moya Moya disease Link: https://som.ucdenver.edu/Profiles/Faculty/Profile/29591

Jennifer Kang, MD Serving at Denver Health Medical Center, Dr. Kang specializes in complex spine, neurotrauma, brain injuries, concussion, and spine cord injuries.

Link: http://www.jenniferkangmd.com/ Daniel Craig, MD Serving the intensive trauma load at Denver Health Hospital, Dr. Craig specializes in general neurosurgery, neurotrauma, and complex spine.

Link: https://som.ucdenver.edu/Profiles/Faculty/ Profile/15008 Alexander Mason, MD Dr. Mason serves at Denver Health Hospital and specializes in general neurosurgery, neuro trauma and more.

Link: https://www.denverhealth.org/providerdirectory/m/mason-alexander-m

NEUROPSYCHOLOGY Brian Hoyt, PhD Dr. Hoyt directs this division and specializes in the neuropsychological testing necessary for neuro surgical patients, including those with epilepsy, movement disorders/deep brain stimulation, dementia, multiple sclerosis, stroke, traumatic brain injury and other neurological and medical disorders.

Link: https://www.cudoctors.com/Find_A_Doctor/Profile/18233 Michael Greher, PhD Dr. Greher leads our neuropsych training and specializes in the testing of potential neurosurgical patients who have epilepsy, movement disorders/DBS, dementia, stroke, traumatic brain injury and other neurological and medical disorders.

Link: https://www.cudoctors.com/Find_A_Doctor/Profile/18174 Thomas Wodushek, PhD Dr. Wodushek is the clinical director of this service at UC Anschutz, and specializes in the relationship between various neurologic diseases or injuries and their impact on patients cognitive and emotional functioning.

Link: https://www.cudoctors.com/Find_A_Doctor/Profile/20586

Joie Molden, PhD Having recently completed her fellowship in neuropsych here a CU, Dr. Molden is particularly interested in memory disorders and neuro degenerative disorders.

Link: https://medschool.cuanschutz.edu/ alzheimer/about/directory/fellows/joiemolden Christopher Domen, PhD Specializing in neuropsychological testing and diagnostics, particularly with potential neuro surgical patients.

Link: https://www.cudoctors.com/ Find_A_Doctor/Profile/11043 To schedule any neuropsycology appointments, call 720-848-4469.

NEUROSURGICAL RESEARCH Cristin Welle, PhD Dr. Welle is the Vice Chair of Research for our department. She has her own BIOElectrics Lab that investigates how neurological medical devices interact with the nervous system. Our goal is to understand the dynamic interactions between devices and neural circuits in the context of translational neurotechnology.

Link: https://som.ucdenver.edu/Profiles/Faculty/Profile/23859 Michael Graner, PhD Currently working primarily on brain tumor research, Dr. Graner specializes in research with exosomes (the smallest type of extracellular vesicles).

Link: https://som.ucdenver.edu/Profiles/Faculty/Profile/6355 Judith Gault, PhD Dr. Gault’s research is currently studying ethical issues surrounding deep brain stimulation for the treatment of schizophrenia.

Link: https://som.ucdenver.edu/Profiles/Faculty/Profile/6802 John Thompson, PhD The recipient of a Boettcher Investigator Award and a Webb-Waring Biomedical Research Award, Dr. Thompson is primarily studying how the central nervous system converts incoming sensory stimuli into motor commands in human subjects.

Link: https://som.ucdenver.edu/Profiles/Faculty/Profile/22302 Xiaoli Yu, PhD Dr. Yu’s research interests include immunopathogenesis of Multiple Sclerosis, and phage-displayed random peptide library approaches to identify extracellular vesicles/exosomes as biomarkers for patients with brain tumors, traumatic brain injuries and other CNS disorders.

Link: https://som.ucdenver.edu/Profiles/Faculty/Profile/7376 Pamela David Gerecht, PhD Pamela supports research in Stereotactic and Functional Neurosurgery via coordination of numerous industry-sponsored and investigator-initiated trials.

Link: https://som.ucdenver.edu/Profiles/Faculty/Profile/21041

CONGRATULATIONS!

NEWEST FUNDING IN NEUROSURGERY RESEARCH NIH R33 Award to Principal Investigators, Michael Graner, PhD and Xiaoli Yu, PhD Funding will be provided through 2023 for the project, “Development of Validation of Phage-Displayed Random Peptide LibrariesTechnologies for Rapid Isolation and Characterization of Extracellular Vesicles from Patients with Brain Tumors” NIH R25 Award to MPI, Dr. Cristin Welle, PhD. Funding provided through the University of Minnesota, through 2022 for “Educational Program on Translating Neural Medical Devices.”

NIH R01 to Dr. Steve Ojemann, in conjunction with Brigham & Women’s Hospital. “System Genetics Approach to Intracranial Aneurisms.”

Funding through 2024.

Clinical Trial, sponsored by Medtronic, to Dr. Chris Roark.

Project through 2025 to study Embolization of the Middle Meningeal Artery with ONYXTM Liquid Embolic System in the Treatment of

NIH UH3 with University of Nebraska, to Dr. John Thompson. Funding through 2025 for Adaptive Neurostimulation to Restore Sleep in Parkinson’s Disease: An Investigation of STN LFP Biomarkers in Sleep Dysregulation and Repair. Pilot Grant from the Movement Disorders Center to Dr. John Thompson for funding through 2021. Sleep assessed by actigraphy and direct recordings of the subthalamic nucleus in Parkinson’s Disease.

Clinical Trial, sponsored by Medtronic to Dr. David Case. Project through 2024 to study EndoVasular treatment for Acutely ruptured shallow intradural aneurysms Not amendable To clipping And/or coilinG with the PipelineTM Vantage Embolization device (“VANTAGE” Study).

Congratulations to Dr. David Case for being appointed to the Colorado Stroke Advisory Board by Governor Jared Polis. This an exciting honor and opportunity to improve stroke care and systems throughout the state.

Next Edition: Stay tuned for a recap of ALL current research funding in Neurosurgery! It’s impressive!

THANK YOU TO OUR GENEROUS DONORS! YOU ARE MOVING NEUROSURGERY FORWARD IN COLORADO

$500,000 gift (over five years) from a generous donor to Dr. Josh Seinfeld for research in device development for hemorrhagic stroke

$100,000 gift from a generous donor to Dr. Kevin Lillehei and Dr. Michael Graner for their research in glioblastoma!

$25,000 gift from a grateful patient to our Neurosurgery/ Oncology Research Fund!

$15,000 gift from grateful patient to help Dr. Wayne Gluf set up a neuro critical care research fund

PUBLICATIONS ABOUND!

BRAVO TO ALL OF OUR AUTHORS AND INVESTIGATORS! David Case, Joshua Seinfeld, Chris Roark, Robert Neumann, Luis Cava and Jason Weedman Cerebral Venous Thrombosis and COVID-19: a Case Report and Review of the Literature, published in Journal of Vascular and Interventional Neuroradiology Link: https://medschool.cuanschutz.edu/docs/librariesprovider62/default-document-library/case--published.pdf?Status=Temp&sfvrsn=fd7acb9_2 David Case, MD “No time delay for Large Vessel Occlusion” Link: https://n.neurology.org/content/early/2020/09/17/WNL.0000000000010915 Marissa Powell, manuscript on anticoagulation for central venous thrombosis was accepted to Annals of Pharmacotherapy. Marissa was precepted

by Dr. David Case from neurosurgery. Congratulations to Marissa!!

Xiaoli Yu, PhD and Michael Graner, PhD for the following publications: Antibodies from multiple sclerosis brain identified Epstein-Barr virus nuclear antigen 1 & 2 epitopes which are recognized by oligoclonal bands. Wang Z, Kennedy PGE, Dupree C, Wang M, Lee C, Pointon T, Langford TD, Graner MW*, Yu X*. J Neuroimmune Pharmacol. 2020 Aug 18. doi: 10.1007/ s11481-020-09948-1. Online ahead of print. *Co-Senior Author PMID: 32808238 Link: https://link.springer.com/article/10.1007/s11481-020-09948-1 Recombinant antibodies derived from laser captured single plasma cells of multiple sclerosis brain identified phage peptides which may be used as tools for characterizing intrathecal IgG response. Kennedy PGE, Graner MW, Walker D, Pointon T, Fringuello A, Yu X. J Neuroimmunol. 2020 Jul 14;347:577319. doi: 10.1016/j.jneuroim.2020.577319. Online ahead of print. PMID: 32717427 Link: https://www-sciencedirect-com.proxy.hsl.ucdenver.edu/science/article/pii/S0165572820302988 Exosome Isolation by Ultracentrifugation and Precipitation: A Comparison of Techniques for Downstream Analyses. Coughlan C, Bruce K, Burgy O, Boyd TD, Michel CR, Garcia-Perez JE, Adame V, Anton P, Bettcher BM, Chial HJ, Koenigshoff M, Hsieh EWY, Graner M, Potter H. Curr Protoc Cell Biol. 2020 Sep;88(1):e110. doi: 10.1002/cpcb.110. PMID: 32633898 Varicella-Zoster Virus infected human neurons are resistant to apoptosis. Kennedy PGE*, Graner MW*, Gunaydin D, Bowlin J, Pointon T, Yu X. J Neurovirol. 2020 Mar 3. doi: 10.1007/s13365-020-00831-6. [Epub ahead of print] *Co-First Author PMID: 32125664 Link: https://link.springer.com/article/10.1007%2Fs13365-020-00831-6

Todd Hankinson, MD for the following publications: Single-Cell RNA Sequencing of Childhood Ependymoma Reveals Neoplastic Cell Subpopulations That Impact Molecular Classification and Etiology AE Gillen, KA Riemondy, V Amani, AM Griesinger… - Cell Reports, 2020 Ependymoma (EPN) is a brain tumor commonly presenting in childhood that remains fatal in most children. Intra-tumoral cellular heterogeneity in bulktumor samples significantly confounds our understanding of EPN biology, impeding development of …

Link: https://www.sciencedirect.com/science/article/pii/S2211124720310081 Evaluation of 2011 AAP cervical spine screening guidelines for children with Down Syndrome AC Hengartner, R Whelan, R Maj… - Child’s Nervous System, 2020 Purpose Atlantoaxial instability (AAI) has a higher incidence rate among individuals with Down syndrome (DS) than the non-DS population. In 2011, the American Academy of Pediatrics (AAP) updated its AAI screening guidelines for children with …

Link: https://link.springer.com/article/10.1007/s00381-020-04855-5 Dr. Kevin Lillehei for the following publications: Defining the timing and role of acute postoperative imaging in pituitary adenoma surgery: clinical study KE Kunigelis, G Arnone, G Chatain, J Hoffman… - Acta Neurochirurgica, 2020 Background: The ideal timing of postoperative imaging after pituitary adenoma surgery has yet to be determined. We reviewed our pituitary database to determine whether timing of routine postoperative imaging has significantly changed patients’ …

Link: https://link.springer.com/article/10.1007/s00701-020-04515-2 Surgical Management Considerations in Cystic Prolactinomas a Single Center Case Series.

Link: https://link.springer.com/article/10.1007%2Fs12020-019-02076-8

The use of intraoperative neurosgical ultrasound for surgical navigation in low and middle income countries.

Link: https://thejns.org/view/journals/j-neurosurg/aop/article-10.3171-2019.12.JNS192851/article-10.3171-2019.12.JNS192851.xml

Reliability of Flueroescein-assisted stereotactic brain biopsies in predicting conclusive tissue diagnosis Link: https://link.springer.com/article/10.1007/s00701-020-04318-5

Drs. Kevin Lillehei, Ryan Ormond, Michael Handler and Todd Hankinson for: Advancing Treatment for Pediatric Craniopharyngioma Consortium.

Link: https://actaneurocomms.biomedcentral.com/articles/10.1186/s40478-020-00939-0 Dr. Steven Ojemann RNS modifications to eliminate stimulation-triggered signs or symptoms (STS): Case series and practical guide AM Hixon, MG Brown, D McDermott, S Destefano… - Epilepsy & Behavior, 2020 Responsive neurostimulation (RNS) for intractable epilepsy involves placement of electrodes onto or into the brain that detect seizure activity and then deliver a current to abort a seizure before it spreads. Successful RNS treatment can deliver hundreds …

Link: https://www.sciencedirect.com/science/article/pii/S1525505020305060 Dr. David Ryan Ormond for the following publications: Photomicrograph-Based Neuropathology Consultation in TanzaniaThe Utility of Static-Image Teleneuropathology in Low-and Middle-Income Countries F Zerd, BE Moore, AE Malango, PW Hosokawa… - American Journal of Clinical …, 2020 Objectives Since neuropathologic diagnosis in the developing world is hampered by limitations in technical infrastructure, trained laboratory personnel, and subspecialty-trained pathologists, the use of telepathology for diagnostic support, second-opinion …

Link: https://academic.oup.com/ajcp/advance-article/doi/10.1093/ajcp/aqaa084/5876645

Photomicrograph-Based Neuropathology Consultation in Tanzania F Zerd, BE Moore, AE Malango, PW Hosokawa… - American journal of clinical …

Objectives Since neuropathologic diagnosis in the developing world is hampered by limitations in technical infrastructure, trained laboratory personnel, and subspecialty-trained pathologists, the use of telepathology for diagnostic support, second-opinion …

Link: https://pubmed.ncbi.nlm.nih.gov/32715312/ Dr. Joshua Seinfeld Reconstruction of Complex Scalp Defect After Cirsoid Aneurysm Resection: A Multidisciplinary Approach TH Ung, MR Delcont, S Colakoglu, J Seinfeld, B French… - World Neurosurgery, 2020 Background Scalp arteriovenous malformations, also known as cirsoid aneurysms, are complex collections of directly communicating arteries and veins. As a cirsoid aneurysm grows, it may recruit blood supply from multiple intracranial and …

Link: https://www.sciencedirect.com/science/article/pii/S1878875020316223 Dr. Samy Youssef for the following publications: Surgical management of craniopharyngiomas in adult patients: a systematic review and consensus statement on behalf of the EANS skull base section.

Cossu G, Jouanneau E, Cavallo LM, Elbabaa SK, Giammattei L, Starnoni D, Barges-Coll J, Cappabianca P, Benes V, Baskaya MK, Bruneau M, Meling T, Schaller K, Chacko AG, Youssef AS, Mazzatenta D, Ammirati M, Dufour H, Laws E, Berhouma M, Daniel RT, Messerer M.Acta Neurochir (Wien). 2020 May;162(5):1159-1177. doi: 10.1007/s00701-020-04265-1. Epub 2020 Feb 28.PMID: 32112169 Review.

Link: https://pubmed.ncbi.nlm.nih.gov/32112169/

Defining the timing and role of acute postoperative imaging in pituitary adenoma surgery: clinical study.

Kunigelis KE, Arnone G, Chatain G, Hoffman J, Chatain O, Coulter I, Sunshine A, Lillehei KO, Youssef AS.Acta Neurochir (Wien). 2020 Aug 11. doi: 10.1007/s00701-020-04515-2. Online ahead of print.PMID: 32779027 Link: https://pubmed.ncbi.nlm.nih.gov/32779027/

The Combined Endoscopic Endonasal Far Medial and Open Postauricular Transtemporal Approaches As a Lesser Invasive Approach to the Jugular Foramen: Anatomic Morphometric Study With Case Illustration.

Youssef AS, Arnone GD, Farell NF, Thompson JA, Ramakrishnan VR, Gubbels S, Cohen-Gadol AA, Cass S, Labib MA.Oper Neurosurg (Hagerstown). 2020 Jun 8:opaa080. doi: 10.1093/ons/opaa080. Online ahead of print.PMID: 32510567 Link: https://pubmed.ncbi.nlm.nih.gov/32510567/

The predictive value of preoperative apparent diffusion coefficient (ADC) for facial nerve outcomes after vestibular schwannoma resection: clinical study.

Kunigelis KE, Hosokawa P, Arnone G, Raban D, Starr A, Gurau A, Sunshine A, Bunn J, Thaker AA, Youssef AS.Acta Neurochir (Wien).

2020 Aug;162(8):1995-2005. doi: 10.1007/s00701-020-04338-1. Epub 2020 May 21.PMID: 32440924 Link: https://pubmed.ncbi.nlm.nih.gov/32440924/ The endoscopic endonasal eustachian tube anterolateral mobilization strategy: minimizing the cost of the extreme-medial approach.

Labib MA, Belykh E, Cavallo C, Zhao X, Prevedello DM, Carrau RL, Little AS, Ferreira MAT, Preul MC, Youssef AS, Nakaji P.J Neurosurg.

2020 Mar 13:1-12. doi: 10.3171/2019.12.JNS192285. Online ahead of print.PMID: 32168475 Link: https://pubmed.ncbi.nlm.nih.gov/32168475/

BRAIN TUMOR PATIENT SPEAKS ABOUT HER EXPERIENCE SEEKING HOPE AND COMMUNITY

Current brain tumor patient, Jessica L, recently spoke with Dr. Kevin Lillehei about her very difficult glioblastoma diagnosis. “The hardest part has been the lack of hope. I don’t need to be reminded of the horrible statistics associated with this diagnosis. I’m so glad I eventually made my way to the University Hospital. The Neurosurgery Department and the Cancer Center at CU Anschutz have been wonderful.” Jessica’s amazing friends organized a month long awareness and fundraising campaign, “Vibin4Jess” in August that virtually brought people together to offer hope, set their own challenges, and talk about the issues associated with this difficult diagnosis. About $2,000 was raised for brain tumor research at CU, Department of Neurosurgery. It is our hope that this will continue and be an annual event. Many thanks to all who were involved!

Good luck, Jessica. You are loved!

“The Neurosurgery Department and the Cancer Center at CU Anschutz have been wonderful.”