2019 Wisconsin Breast Cancer Showhouse

2019

SHOWHOUSE for a Cure

June 1~June 16, 2019 Plankinton Clover Apartments @ The Avenue 161 West Wisconsin Avenue, Milwaukee, WI n

DEAR WBCS Guests, Friends & Sponsors Welcome to the 22nd Showhouse for a Cure. This year’s Showhouse is a major departure from all of the past Showhouses – instead of a venerable and historic home, this Showhouse is a group of seven, newly built apartments located in Plankinton Clover Apartments in The Avenue, a redevelopment of the historic Grand Avenue Mall and Plankinton Arcade. For many of you Ellen Irion this site will be teeming with memories of your childhood and the childhoods of your children and even grandchildren. Now it will become part of our collective memory as the re-birth of this historic building and as the site of the Milwaukee community supporting the WBCS mission – breast cancer and prostate cancer research.

Prostate cancer will affect one man in seven and breast cancer will affect one woman in eight in their lifetimes. In 2019, the American Cancer Society projects there will be 271,270 new cases of breast cancer and 174,650 new cases of prostate cancer. These numbers are sobering – they confirm we have hard work ahead of us to help insure future generations will have significantly improved protocols for dealing with these devastating diseases and, eventually, cures.

Each of us has our own reason of why we do what we

do. Perhaps it was an aunt, grandmother, our twin or mother; perhaps a father or uncle or a fraternity brother. Regardless of why, what we do about this matters, it will help those in the future, whether that future is next year or five years or fifty years.

There are so many to thank. It would be impossible to have the Showhouse without the generosity of this year’s owners, Josh Krsnak of Hempel Companies and Tony Janowiec of Interstate Parking. They have not only provided the apartments for the Showhouse but have provided complimentary parking for everyone involved in creating the Showhouse plus all of the guests.

There simply is no way to thank the designers for the extraordinary time, effort and talent invested in creating these memorable spaces.

Year after year they create magic. There are over 900 volunteers.

Thank you! Without you there would be no Showhouse. Thank you to Northwestern Mutual Foundation, our Presenting Showhouse Sponsor, for their continuing support to the mission; Froedtert, our Gala Presenting Sponsor; the Brewers Community Foundation, the Pinktacular Presenting Sponsor; Argosy Foundation and Susan and Bob Mikulay for their years of support. And of course to you our guests who attend our events from the Raise a Glass to Hope Gala, the Showhouse for a Cure, Tee-Up for a Cure and the Pinktacular Luncheon and Fashion Show, thank you and thank you again for supporting our mission.

Ellen Irion Chair, WBCS Board of Directors

2019 INDEX of Advertisers, Designers, Sponsors,WBCS Research & Financial Reports DESIGNERS Alexandra Wood Design....................................31 Bachman Furniture..............................................27 calico.....................................................................41,42 Elements East.........................................................37 Ethan Allen..............................................................38 Fringe...................................................................32,33 g. Home....................................................................25 Haven Interiors.......................................................29 The Home Market................................................39 Ivy Interiors..............................................................36 Ken Michaels Furniture.......................................24 Modern Health and Living...............................40 Nicholas Carl Design.....................................26, 28 Betsy Peckenpaugh.......................................41, 42 Residence.........................................................34, 35 Suzan J Designs......................................................30 WBCS, INC. Christy Foote Fighter Award 2019....................22 Did You Know FAQ’s.............................................13 Directors and Committees..............................5, 7 Message from President......................................3 Showhouse Dedication 2019 Honoree........21 Financial Information for the Year ending December 2018.....................................13 2019 SHOWHOUSE for a Cure

SHOWHOUSE 2019 Past Showhouses................................................44 Showhouse History.............................................23 Showhouse Rooms 2019...........................24-42

KenMichaels..............................................................51 Medical College of Wisconsin...........................8 Pandl’s.......................................................................46 Shorewest Realtors..........................Back Cover

WBCS EVENTS Tee Up for Cure Golf and Gala........................50 Pinktacular Fashion Show and Luncheon....................................................45

WBCS SPONSORS, DONORS AND SUPPORTERS Brewers Community Fund.................................6 Bronze Donors........................................................10 Community Partnerships...................................12 Donors.........................................................................11 Friends........................................................................10 Give Back Designers............................................48 Give Back Restaurants.......................................46 Gold Sponsors.........................................................9 In-Kind Donations and Services..................11, 12 Platinum Sponsor...................................................9 Presenting Sponsor................................................9 Silver Sponsors.........................................................9 Ticket Outlets...........................................................12 Volunteer Opportunities.....................................12

SCIENCE AND RESEARCH Breast Cancer Progress Report.........................18 Impact Report..........................................................16 Prostate Cancer Progress Report..............19, 20 Research for a Cure...............................................14 Researcher Grants Report...................................15 ADVERTISERS ABCD, after breast cancer diagnosis............48 Ansay Insurance....................................................50 Café 1505..................................................................46 Elements East.........................................................48 Ethan Allen..................................................................4 Friends of Villa Terrace........................................48 Froedtert Hospital...................................................2 Haven Interiors........................................................48 Hollander House on Downer..........................46

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2019 WBCS Directors & Committees

2019 WBCS Board of Directors Seated, l to r: Vera Wilson; Jan Lennon; Ellen Irion, Chair; Kellee Selden; Kim Jones.

Standing, l to r: Linda Short; Margie Edwards; Kadie Jelenchick; Patty Virnig; Kathleen Dean. Not pictured: Colleen Reilly and Claudia Gavery.

2019 WBCS Board Chair Ellen Irion

2019 WBCS Development & Chair, Scientific Review Committee Jan Lennon

2019 WBCS Boutique Committee ~ Vera Wilson, Chair

2019 Design Review Committee Patty Virnig, Chair

2019 WBCS Homeowner Liaison ~ Kadie Jelenchick

2019 WBCS Raise a Glass to Hope Preview Party Kellee Selden, Chair

2019 SHOWHOUSE for a Cure

2019 WBCS Public Relations & Marketing; Volunteer Coordinator ~ Linda Short, Chair

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2019 WBCS Directors & Committees

2019 WBCS Design Review Committee front row, l to r: Ellen Irion; Claudia Gavery; Judy Gehl.

Back row, l to r: John Edbauer; Kerry Shannon; Patty Virnig, Chair; Nick Konzal; Jeff McEathron.

2019 WBCS Pinktacular Survivor Luncheon Arlene Wesson, Kathy Dean, Co-Chairs

2019 WBCS Fashion Show Bazaar Katie Glaisner, Julie Lutz, Co-Chairs

2019 WBCS Tee Up for a Cure Golf Outing® and Gala Dinner. WBCS Board of Directors

2019 WBCS Photographer John Kimpel

2019 WBCS Attorney David Lowe

~ In Memoriam ~ WBCS acknowledges with sadness the May 11 passing of Elaine Pandl, our founding treasurer and longtime volunteer. Elaine died just a few days before celebrating her 90th birthday. Her gentle mentoring and thoughtful guidance benefited our organization and kept us on a strong footing during our fledgling years. We will miss her quick wit, her wonderful smile, and her unwavering loyalty to family, colleagues and friends. Elaine’s son, John, third generation owner of the iconic Pandl’s Whitefish Bay Inn, continues to support WBCS and bring awareness of our mission to restaurant patrons through his annual jade plant sale and participation in the WBCS restaurant cash back program. Godspeed, Elaine. You will be remembered by all of us whose lives you have touched. l to r: John Pandl; Laura, his wife; Elaine; Ryan Pandl, son of John and Laura.

2019 SHOWHOUSE for a Cure

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2019 SHOWHOUSE Presenting Sponsors & Donors SHOWHOUSE Presenting Sponsor

PLATINUM SPONSORS $15,000 ~ $24,999

Susan and Bob Mikulay GOLD SPONSORS $10,000 ~ $14,999 Frieda and William Hunt Memorial Trust in honor of Linda Short Kadie and Steve Jelenchick

SILVER SPONSORS $5,000 ~ $9,999

Mark F. Blake, MD Mark W. Bosbous, MD Family Four-Four Foundation John Klink Landmark Healthcare Facilities, LLC 2019 SHOWHOUSE for a Cure

Jan Lennon Toomavara Partners LLC Diane and Ed Zore 9

2019 SHOWHOUSE Sponsors & Donors BRONZE DONORS $1,000 ~ $4,999 2018 Showhouse Docents & Volunteers 2019 Raise a Glass to Hope Committee Badgers Lodge No. 584 SNPJ Baird Bartolotta Restaurant Group Carroll University Blaze Dance Team, Julie Rapps, PhD Jai Cheney, Jai Bird Productions CIBC Bank USA Kathleen & Randy Dean Christopher Doerr Margie Edwards Eppstein Uhen Architects, Inc. Susy Ettinger Fox, O’Neill, Shannon S.C. Thomas Fritz Groth Design Team Heartland Financial USA, Inc. Evan & Marion Helfaer Foundation Hupy & Abraham, S.C. Ellen Irion J.W. Speaker Corporation Kimberly & Todd Jones Marcia Klode, Mille Tesori Design Studio Juliane H. Lee MD The Luther Group

Marquette Associates Archie & Viola Meinerz Foundation MGIC Kathryn & Mark Mohr Anne Mongoven Kim Nowak Park Bank Foundation Physicians Realty Trust Greg Renz C G Schmidt Shorewest Realtors Karen & David Simon, MD Dr. & Mrs. Sal Spicuzza Umansky Motor Cars United Way of Greater Milwaukee and Waukesha County Patricia & James Walden WaterStone Bank SSB West Bend Mutual Insurance Company Charitable Fund Vera & J. Frank Wilson, MD Wipfli LLP Lisa and Paul Wysocki, Blossom Charitable Trust

FRIENDS $250 ~ $999 American Legion Post 537 Barbara Barrow Daniel Cowell Cream City Gifts Peggy & Ronald Creten Maripat & Tom Dalum Julie Dreckmann Tammy Easton Donna Faw First American Title Ins. Co. Maurius Fuhr Fun-O-Leers Charity Susan Gebhardt Owen Griffith PhD Mark Grzesiak Elizabeth & Charles Haas Rose Halik Herbert H. Kohl Charities Historic Water Tower Neighborhood Assoc.

Nic Hoyer Diane Jenkins Mary & Michael Jordan KP! Toffee Daniel Krivos Christina Land Sue Madden Kevin Malaney and Aspen Antonio Jodi Marcus Ann Margolis 10

Colleen McCauries Diane McGinn Midtown Dental Care Anthony Mlinar Michael Mlinar John Pandl Pandl’s Whitefish Bay Inn Regal Photo Products, Inc. Colleen Reilly Carol Richheimer Betsy Roberts Nancy & Mike Roos Francine Rubinstein Linda Sampson David Scherbarth Carol & Robert Schmidt Julie Schnoll Mary Louise & Jeffrey Schwab Katherine & William Shaffer Linda Short Nita Soref Steir Construction, Inc. Donna Strong Catherine Styza Treymed, Inc. Arlene Wesson Carol Williams PhD Wisconsin Athletic Club Mary-Jo Zore 2019 SHOWHOUSE for a Cure

2019 SHOWHOUSE Sponsors & Donors DONORS $100 ~ $249 Diane Aiello Alice Aranguren Beacon Business Group, Inc. Belle City Metal Products Inc. Kara Berrie Bevsek-Verbick Funeral Home The Boulder Group Brown Deer Bay Point Women’s Nine Hole Golf Club Café 1505 Thomas Christie Carla Cohen Laura & Jeffrey Davidson Patricia DeJong designXchange Peggy & Sam Dickman Patricia & John Dowd Eileen and Howard Dubner Donor Advised Fund Ranee & Brent Field Susie & Bob Fono Barbara Fuldner Claudia & Raymond Gavery

General Plastics, Inc. Susie Gerschwiler Joyce Gudeman Leslie Hauser Holz Motors Elinor & J. Paul Jacobson Jimmy B’s Trails End, Inc. Christina Keppel Susie Keprowski Joan & Henry Kerns Timothy Kraetsch Lynne & Sylvan Leabman Janet Levy The Lowlands Group LLC Scott and Jodi Lurie Family Donor Advised Fund Diana Luttman Marco Machine Inc. Tracy & Dane Miller Laurence Mlinar Linda Oaks Scott Obernberger Mary Pindyck

Ann Ranfranz Lynette Riehle Ritz Holman LLP Bela Roongra Guy Schmitz Kellee Selden Suzanne Selig Amalie & Robert Smole and Family Patricia Stapelkamp Mary Steinbauer Judy Steinke Sugar Cane Tavern Marilyn & Robert Teper Tri City Black Belt Academy LLC Tushaus & Associates LLC Ken Voigt U. S. Bank Foundation West Allis West Lions Club Helen Wilson Margaret Wittkowske Wolf River Leather Woller-Anger & Company, LLC Carol Wythe

IN-KIND DONATIONS & MEDIA 4 Paws Grooming Allen Edmonds Company Bartolotta Restaurant Group Beans & Barley Cafe Belabela Big Bang LLC Blommer Chocolate Company Boelter Superstore John Bosbous The Boulder Group Brewers Community Foundation Squeakie Bruce The Bull at Pinehurst Farms C G Schmidt Burke Candy Café Corazon Canopies Jai Cherney Cheese Cake Factory Chocolate Factory Sensational Subs & Sundaes Lisa Collins Cream City Gifts LLC DanDan Kathleen & Randy Dean Delicately Delicious Dodco Julie Dreckmann Elite Sports Clubs Elements East Elsa’s On the Park Faye’s Terry Fetherston First American Title Fleming’s Prime Steakhouse & Wine Bar The Florentine Opera Fred Astaire Dance Studios Julie Frinzi Joyce Garbaciak of WISN TV 12 Gigi of Mequon Ginza Japanese Restaurant 2019 SHOWHOUSE for a Cure

Green Bay Packers Foundation Grohmann Museum | MSOE, James Kieselberg, II Director Liz Haagensen Harley’s the Store for Men Hempel Companies Nancy Herrick Sam Hill/Rohr Jewelers Linda Hoffman Honey Pie & Palomino Bar Ian’s Pizza The Ingleside Hotel Impressions Salon Institute for Athletic Acupuncture, LLC Interstate Parking Ellen Irion Tony Janoweic Jet’s Pizza Jing’s Kalahari Resort Kesslers Diamonds John Kimpel Marcia Klode/Mille Tesori Design Studio Nick Knozal KP! Toffee Josh Krsnak Daniel G. Krivos Lai Lida Cookies La Lune Collection Peggy LeBrun Juliane H. Lee, MD Jan Lennon Lowlands Group Margie Edwards Jewelry Designs Maxie’s Blue’s Egg Medical College of Wisconsin Midtown Dental Care Susan and Bob Mikulay Miller Coors Milwaukee Art Museum Milwaukee Film, LLC

Minasians in Evanston MKE Lifestyle Kathryn & Mark Mohr Motor Bar & Restaurant/ Harley Davidson Museum Ned’s Pizza Neroli Salon & Spa Nicholas Konzal Designs Nothing Bundt Cakes Andy Nunemaker Oro Oil & Wine - Glendale Otto’s Wine & Spirits–Cedarburg Otto’s Wine & Spirits–Milwaukee Outpost Natural Foods P. F. Chang’s Paper Source Paragon Printing and Graphics Parkside 23 Pastiche Bistro & Wine Bar Piggly Wiggly Mequon PRP Wine Q’ticles Colleen Reilly Rock Bottom Restaurant & Brewery Roots Salon & Spa Betty Rubner Ryan Companies Sala Italian Restaurant Samano’s Mexican Restaurant Samm’s Memories Schlitz Audubon Nature Center Bill Schroeder Kellee Selden Sharp Brothers Patti Sherry SHOP Shorewest Realtors Linda Short Small Animal Hospital Sobelman’s Pub & Grill Southwest Airlines 11

2019 SHOWHOUSE Partners & Volunteers IN-KIND DONATIONS

Continued

Kate Spade The Spice House Stella & Dot Stier Construction Sunset Playhouse The Swinging Door Tavern Patricia Testor Time Flies Toys Transfer Pizza Twigs Uhle Tobacco Company Vibrant Body Company Villa Terrace/Charles Allis Museums WBCS Board Members

Ward’s House of Prime While You Were Out Pets Wild Birds Unlimited–Mequon J. Frank Wilson, MD Wisconsin Club Yellow Wood on Silver Spring Zaffiro’s Pizza Zarletti Restaurant Mike Zei Zilli Hospitality Group Our Friends In The Media BIG FM 957 Joanne Kempinger Demski

Fox 6 Joyce Garbaciak of WISN TV 12 KTI COUNTRY 94.5 Milwaukee Journal Sentinel Morning Blend–Today’s TMJ4 News Graphic NOW 97.3 FM WISN TV 12 WMIL 1061 WOKY 920 AM WYMN 88Nine MKE Lifestyle

COMMUNITY PARTNERS Alpha Phi Badgers Lodge No. 584 SNPJ Brown Deer Bay Point Women’s Nine Hole Golf Club Care-a-lotta Carroll University Blaze Dance Team Bob and Susie Fono/ Barnes & Noble – Bayshore

Great Lakes Dart Manufacturing Historic Water Tower Neighborhood Association Slim McGinn’s Irish Pub Amalie and Robert Smole Family in memory of Donna Smole The Vibrant Body Company WAC

Bowling for a Cure

VOLUNTEER OPPORTUNITIES Raise a Glass to Hope Preview Party Auction Solicitation Auction Set-Up Bartenders and House Staffers Day-of-Event Volunteers Set-Up and Clean-Up Volunteers Showhouse for a Cure Docents Captains House Staffers Front Desk Staffers House Sitters Graphic Design House Cleaners Interior Designers Exterior Designers – Lighting, Landscape

PR, Marketing & Advertising Program Advertising Solicitation Copy Writers for Program Radio Stations Solicitation Print Media Solicitation Planning and Distribution of Posters and Yard Signs Showhouse Ticket Distribution Golf Auction Solicitation Auction Set-Up On-Course Volunteers Registration Volunteers Gala Dinner Volunteers Raffle Ticket Sellers

Pinktacular Luncheon Luncheon Committee Table Captains Patron Sponsors Event Day Volunteers Raffle Ticket Sales Gift Cards for a Cure Pinktacular Boutique Boutique Set-Up and Breakdown Boutique Staffing Pinktacular Fashion Show Fashion Show Committee Models Dressers Make-Up and Hair Artists Copy Writer

TICKET OUTLETS also online at www.breastcancershowhouse.org Bayside Bayside Garden Center Bay View G. Groppi Food Market Brookfield calico Ethan Allen Ken Michaels Furniture Sendik’s Fine Foods Shorewest Realtors Cedarburg Wyndrose Fine Jewelry Delafield UPS Store Elm Grove g. home Grafton Shorewest Realtors 12

Greenfield Ken Michaels Furniture Shorewest Realtors Hartland Decore Adore Boutique designXchange The Flower Garden Menomonee Falls Shorewest Realtors Mequon Café 1505 Mille Tesori Design Studio Shorewest Realtors Milwaukee Bachman Furniture Elements East Ken Michaels Furniture Manhattan Textiles

Nehring’s Sendik’s on Downer Riverview Antique Market Shorewest Realtors Mukwonago Shorewest Realtors New Berlin Shorewest Realtors Oconomowoc Fabric Gallery Shorewest Realtors Pewaukee designXchange Racine Shorewest Realtors Shorewood Shorewest Realtors the Workroom

Watertown Shorewest Realtors Waukesha Shorewest Realtors Wauwatosa Shorewest Realtors Steinkellners Decorating Center West Allis Carpet Town West Bend Shorewest Realtors Whitefish Bay Fringe Winkie’s Variety Store

2019 SHOWHOUSE for a Cure

2019 SHOWHOUSE for a Cure Did You Know?

WBCS is an all-volunteer philanthropic organization that invests in promising breast cancer and prostate cancer research. Interior designers, accountants, architects, graphic designers, landscape designers, lawyers, planners, your neighbors and hundreds of others volunteer their time to work together to create our annual events: n Showhouse for a Cure n Raise a Glass to Hope Gala n Tee Up for a Cure Golf Outing and Gala n Pinktacular Luncheon, Fashion Show and Bazaar. Fashions are modeled by breast cancer and prostate cancer survivors.

In addition to these WBCS events, WBCS is supported by others in the greater Milwaukee community. In the past year, Lucky Lanes, Slim McGinn’s, Carroll University Blaze Dance Team & Dr. Julie Rapps and Susie and Bob Fono/Barnes & Noble have each generously supported WBCS by sponsoring events that engaged their customers, clients and local community.

Each year, generous homeowners vacate their residence for three months or longer, giving their home over to 25 or more designers.

Donations to WBCS and revenue from purchased tickets and events are NOT used to decorate the Showhouse. All work done for the annual Showhouse for a Cure is underwritten by the interior designers. They are supported by their firms, suppliers, contractors, friends and families.

WBCS is the largest annual philanthropic donor for adult cancer research to the Medical College of Wisconsin Cancer Center.

Since its 1998 inception, with the help and generosity of the greater Milwaukee community, WBCS has invested $6.8 million for cancer research at the Medical College of Wisconsin (MCW).

Researchers we support have secured an additional $75.9 million in extramural grants to continue the promising research initially funded by WBCS. All research proposals are ranked competitively by peer scientists and the WBCS Scientific Review Committee. This committee recommends only the most promising proposals that fall within the WBCS mission. The WBCS Board of Directors then makes the final decisions, awarding grants to those proposals with the most promising ideas.

WBCS, Inc. is an all-volunteer, 501(c)(3) charitable organization that supports early-stage, promising breast cancer and prostate cancer research at the Medical College of Wisconsin.

WBCS, Inc. Statement of Activities* for the Year Ended December 31, 2018 Revenue** Individual Contributions……………………………………...……….……32,208 Corporate Contributions……….…………………………………….......……4,090 Special Events - Net Revenue* Showhouse………………………………………………………....……86,438 Boutique…………………………………………………………...…………14,423 Showhouse Program…….....……………………………………….(3,893) Raise a Glass to Hope…………………...……………………….……56,994 Tee Up for a Cure………………......………………………………….60,876 Pinktacular Fashion Show and Luncheon….……...........….58,165 Third Party Events……………………………………………….....……19,808 Miscellaneous/Interest Income…………….………......………………………62 Total Net Revenue…………………...........……………………………329,171

Percentage of 2018 Income Donated to MCW Versus Expenses

Assets Held for Future Expenses 5% 2018 Expenses 4%

Expenses Contribution to MCW……………………………………………........……325,000 Management and General……………………………………....…….………16,357 Fundraising……………………………………………………………..………………2,931 Total Expenses……………………………………………….....………344,288 CHANGE IN NET ASSETS………….........………………………………15,117 Net Assets, Beginning of Year……………………………......……….……51,000 NET ASSETS, END OF YEAR…………………………….......……. 35,983

* The Statement of Activities is part of the audited financial statements. ** Revenue is Net of Direct Event Costs.

2019 SHOWHOUSE for a Cure

Contribution to MCW ~ 91%

Cummulative WBCS, Inc. Giving to MCW for Breast Cancer and Prostate Cancer Research: $6,822,000

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2019 RESEARCH for a Cure WBCS, Inc. celebrated the success of its 21st annual Showhouse and events with a $325,000 gift for research to the Medical College of Wisconsin Cancer Center (MCWCC). The cumulative donation

by WBCS since 1998 has risen to $6.8 million. In turn, scientists we have supported have received additional external research funding of $75.9 million, bringing our measurable research impact to $82.7 million. This better than 10:1 ratio on our investment in support of breast cancer and prostate cancer research fuels the commitment of our all-volunteer charity to continue to invest strategically in promising early-stage research with the highest potential for success.

WBCS is the largest annual philanthropic donor to MCWCC for adult cancer research. Without the generous philanthropy of donors and organizations such as WBCS, research at an early-stage would be 2019 Scientific Review Committee Seated, left–right: Ellen Irion; stymied by a lack of funding. Investigators’ ability to Jan Lennon, Chair; Edward Ward. Standing, left–right: Hallgeir Rui, MD, PhD; form hypotheses and collect sufficient data to apply Ravi Misra, PhD; Mark W. Bosbous, MD; Mark F. Blake, MD. for larger grants would be diminished. Focused peer scientists led by Graduate School Dean Ravi Misra, PhD early-stage breast cancer and prostate cancer basic research at reviews proposals falling within the WBCS mission. The peer MCW was ignited by and flourished with the availability of WBCS scientist committee ranks proposals with the same rigor as that support. Once this new source of funding became available, required by National Institutes of Health guidelines. The SRC seasoned MCWCC investigators were encouraged to turn their meets annually to evaluate vetted proposals and approve those attention and research inquiries to address challenges inherent it considers worthy for recommendation to the WBCS board of in these two diseases. Over time, collaborative research teams directors. Any SRC member who has a conflict of interest with emerged and opportunities became more readily available for proposals being presented is excused from the discussion. Dr. junior faculty research funding—all leading to a robust body of Misra presents the proposals and provides a framework on their scientific inquiry and discovery that is benefiting patients fighting potential for advancing research or leading to new avenues of these diseases. discovery. He also discusses the availability of additional MCW research resources that have the ability to enhance potential WBCS ENDOWED CHAIR INITIATIVES success. In addition to considering new proposals, an evaluation One in seven men will face prostate cancer and one in eight of progress for previous awards is provided before releasing women will face breast cancer during their lifetime. Breast funding for a second year. Once voting members have evaluated cancer is a disease that affects men, as well. In response to the the proposals, those chosen for support are presented to the devastating effects of a breast cancer or prostate cancer diagnosis WBCS board of directors for final approval and funding. on patients and their families, the Froedtert & the Medical College WBCS acknowledges the many components that contribute of Wisconsin leadership together established both a Breast to our success. MCWCC scientific expertise, individual, Cancer Center of Excellence and a Prostate Cancer Center of foundation, and corporate donor funding, untold volunteer Excellence to make available the highest level of research and gifts of time and effort, the generosity of talented designers, clinical care an academic medical center can provide. These sustained community support of our events, and supportive centers offer hope to regional, national and international patient MCW leadership that invited WBCS in and continues to provide populations. In 2011 WBCS committed to fund an endowed impactful opportunities to help us make a difference — chair in breast cancer research. In 2015, Hallgeir Rui, MD, PhD was all combine to bring discoveries from bench to bedside and recruited as the WBCS Breast Cancer Research Professor. Dr. Rui’s save lives. Collectively, our appointment has been transformational for the program, and partnership is investing the critical gave impetus to WBCS’s enthusiastic commitment in 2017 to fund innovative capital necessary to an endowed chair in prostate cancer research. We are over 80% transform hope into the reality of of our $1 million goal. All things considered, our hope is to fully survival and a better tomorrow fund the endowment as early as 2020. for breast cancer and prostate cancer patients.

SCIENTIFIC REVIEW COMMITTEE The WBCS Scientific Review Committee (SRC) is charged with stewardship of the funds entrusted to us by donors. The SRC is Peggy LeBrun, Director, composed of knowledgeable survivors, WBCS representatives, Volunteer and Event community oncologists, MCW scientists, and MCWCC leadership.

Fundraising, MCW Office MCWCC calls for proposals each December. A committee of of Development.

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2019 SHOWHOUSE for a Cure

2019 WBCS GRANTS 2019 REPORT TO WBCS on the 2012 WBCS $100,000 Large Center Grant Carol Williams, PhD, and Hallgeir Rui, MD, PhD, Co-Leaders of MCW's Breast Cancer Biology Research Program, prepared this final report on the 2012 WBCS $100,000 Large Center Grant in Breast Cancer Research. The award was provided to foster collaboration among MCW scientists from different breast cancer research areas, with the specific objective to build synergistic breast cancer research collaborations designed to achieve results not attainable by investigators working independently.

With this initial generous large center grant support, MCW’s breast cancer research program has grown significantly since 2012.

The following are some of the accomplishments made since then: n Breast cancer has grown to become the most studied solid tumor type at MCW, ahead of pancreatic cancer and prostate cancer, two other areas of strength. n Growth in breast cancer research publications is notable.

Prior to 2012 there were an average of four breast cancer research publications per year at MCW. In 2018 the number had grown to 29. A majority of these publications are inter-laboratory collaborative efforts. n The current number of breast cancer investigators with external funding is 10. n High clinical trial accrual and strong growth in community outreach efforts in breast cancer have been made.

A key accomplishment of the 2012 award is the formation of the Breast Cancer Biology Interest Group. This group meets weekly on Friday afternoon and continues to foster

Front Row (left to right): Amit Joshi, PhD (Radiology); Guan Chen, PhD (Pharmacology), Mark McNally, PhD (Microbiology and Molecular Genetics); Carmen Bergom, MD PhD (Radiology), Qing Robert Miao, PhD (Surgery); Yunguang Sun, PhD (Pathology). Back Row (left to right): Christopher Chitambar, MD FACP (Hematology and Oncology); Carol Williams, PhD (Pharmacology); Hallgeir Rui, MD PhD (Pathology); A. Craig Mackinnon, MD PhD (Pathology); Michael Flister, PhD (Physiology).

collaborations and synergistic interactions. Many collaborative grants have been awarded for these collaborations, and these efforts continue to grow. Growth in breast cancer research has occurred in basic science, translational science, clinical trial research and population science. The positive effects of this 2012 grant from WBCS are long-lasting and resulting collaborations will continue to propel novel breast cancer research at the MCW Breast Cancer Center of Excellence.

INDEPENDENT SEED GRANTS 2019 Marcelo Bonini, PhD, Associate Professor, Medicine-Endocrinology “Metabolic regulation of immunity in the tumor microenvironment” Tumors grow because their environment shields them from destruction by the immune system. To create an immunosuppressive environment, tumors recruit macrophages. Macrophages are immune cells that are capable of both activating immunity to eliminate tumors or creating an immunosuppressive barrier. Somehow, macrophages that become associated with tumors lose their capacity to activate and rather suppress the immune response. The mechanisms used by tumors to make macrophages act this way are unknown. Our novel hypothesis is that cancer cells release lactate, a metabolite produced by them in large amounts, to force macrophages to become immunosuppressive. Our preliminary data indicate that macrophages immersed in lactate lose their capacity for immune activation while assuming an immunosuppressive phenotype. Hence, this application aims at furthering the idea that lactate secretion by tumors serves the purpose of immunomodulation to co-opt tumor associated macrophages to protect rather than attack cancer.

Marja Nevalainen MD, PhD, Professor, Eminent Scholar, Dept. of Pathology and Pharmacology & Toxicology “Stat5 and Anti-Androgen-Induced Metastatic Phenotype of Prostate Cancer” Treatment options for metastatic prostate cancer (MPC) are limited to androgen-deprivation-therapy. The new-generation anti-androgen, Enzalutamide dominates the clinical space and is FDA approved in pre- and post-chemotherapy settings. Resistance to Enzalutamide arises within 3-6 months, with patients developing terminal castrate-resistant (CR)-MPC. There are no effective therapies for CR-MPC. Our data support a novel concept that Stat5 promotes development of Enzalutamide-resistant prostate cancer (ERPC). We previously showed that Stat5 induces metastatic behavior of PC cells. Also, Enzalutamide has been shown to induce metastatic phenotype of PC. Our new data show that Enzalutamide induces Jak2Stat5 activation in PC. This proposal will test whether Enzalutamide induction of Jak2-Stat5 signaling in PC mediates Enzalutamide promotion of CRMPC and may result in a new therapeutic strategy for ERPC by exploiting Jak2-Stat5 pathway inhibitors that are in clinical development for leukemias.

Our goal is that this project results in development of a new therapy for ERPC.

Second Year Independent Seed Grant Approval Amit Joshi, PhD, Associate Professor, Biomedical Engineering “Personalized Nanomedicine Interventions Targeted to Germline Driven Tumor Vascular Heterogeneity Breast cancer affects 1 in 10 US women in their lifetime. Current treatment for breast cancer involves surgery, chemotherapy and radiation treatment.

These treatments not only cause undesirable side effects, but there is also a high level of inconsistency in how patients respond to treatment even in similar disease types. We suggest that part of this variation in treatment response might be due to inherited genes controlling the blood vessel development in tumors. Patients with favorable inherited blood vessel behavior in tumors have higher drug delivery to tumors, and favorable treatment response, while in others, genetically inherited factors predispose them to more aggressive and therapy resistant tumors. In this proposal, we will address both the low efficacy and side effects of current breast cancer treatments by personalizing treatment through a novel nanoparticle based imaging/therapy approach. We will target inherited blood vessel development controlling genes, to avoid therapy resistance and aggressive behavior in patients with unfavorable inherited genes.

2019 SHOWHOUSE for a Cure

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2019 WBCS IMPACT REPORT The partnership between WBCS and the Medical College of Wisconsin (MCW) impacts research in ways neither could accomplish alone. Since 1998, WBCS, Inc. has donated $6.8 million to MCW for breast cancer and prostate cancer research. Much of this investment has been used for “seed grants”—innovative ideas that have not been tested enough to obtain data to validate their potential. Solving a problem as intractable as breast cancer or prostate cancer requires big-picture thinking.

Seed grants allow researchers to imagine a new way of thinking, build on an idea in its infancy or move a concept into an entirely new direction. By supporting research at its earliest stages, this philanthropic “risk capital” has the potential for significant long-term return. A seed grant is typically the first step in developing new treatments and, ultimately, in identifying potential cures. While the progression from a seed grant idea to a cure is almost never a straight line, no new treatment, no disease cure has ever been developed without this foundation.

The return quite simply cannot be overstated.

In dollar terms alone, WBCS has had a significant impact by helping researchers secure larger awards from other funding organizations. To date, WBCS seed grants have brought $75.9 million in additional funding to the MCW Cancer Center. Examples of two of the brilliant researchers from MCW who have advanced research in significant ways, thanks in part to WBCS funding, are described below.

EXAMPLE: “Harnessing Dual-Specific T Cells in Breast Cancer Immunotherapy” In 2014, Weiguo Cui, PhD, currently Associate Investigator, Blood Research Institute, Versiti BloodCenter of Wisconsin and Assistant Professor, Microbiology, Medical College of Wisconsin, received Michael Dwinell, PhD a two-year $100,000 WBCS grant for the project Dr. Cui’s research in this area resulted in an innovative “Harnessing Dual-Specific T Cells in Breast Cancer approach to using CAR-T cells to treat solid tumors. He is Immunotherapy.” The goal of this study was to determine if currently in the process of moving this technology to the immunotherapy, one of the most promising cancer treatments, clinical trial phase. has the potential to be an effective treatment for breast cancer.

Immunotherapy uses substances to stimulate or suppress EXAMPLE: “CXCL12 Treatment as a a person’s immune system to help the body fight cancer, Novel Therapeutic Paradigm for Breast Cancer” oftentimes by targeting certain cells of the immune system.

In 2011, Michael B. Dwinell, PhD, currently Professor of For Dr. Cui, the WBCS award was Microbiology & Immunology and Surgery, Founding Director, the first grant to support his research Center for Immunology, Director, Bobbie Nick Voss Laboratory, in cancer immunotherapy. Previously, and Leader, Molecular Cancer Therapeutics, at the Medical he focused primarily on studying College of Wisconsin, received a two-year $100,000 WBCS fundamental biology in immune cell grant for the research project, “CXCL12 Treatment as a Novel development and function.

Therapeutic Paradigm for Breast Cancer.”

“The support (from WBCS) was This study looked at a specific molecule of the body’s immune pivotal for me, allowing me to shift into system, called CXCL12, which plays a key role in recognizing and the field of cancer immunotherapy, preventing cancer. As cancer cells transform into malignant which I found more exciting and Weiguo Cui, PhD tumors, the immune system is either suppressed or evaded by impactful,” Dr. Cui said. cancer cells. Research in Dr. Dwinell’s lab shows that the CXCL12 “Not only did this award provide the money I needed to gene is silenced and repressed in cancer cells, and this repression build up my research portfolio, it also boosted my confidence in “turns off” a key immune signal that limits the ability of cancer cells developing new technologies in cancer immunotherapy.”

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2019 SHOWHOUSE for a Cure

to spread to other organs (metastasize). Importantly, the WBCS grant allowed Dr. Dwinell’s team to discover that when the lost molecule is “replaced” using an injection, the ability of cancer cells to grow and metastasize is inhibited. This replacement treatment acts to increase the survival of tumor bearing animals.

According to Dr. Dwinell, “The WBCS grant was instrumental in my laboratory’s ability to complete paradigm shifting research that establishes the CXCL12 chemokine as a new tumor suppressor.”

Dr. Dwinell also observed, “This very concept is new to the field of oncology and has been validated in breast cancer using WBCS funds, but also in colon cancer, pancreatic cancer and lung cancer as well. We are excited by the potential to replace this molecule as an innovative strategy to treat cancer.

We were honored and immensely grateful to all of our friends and partners in the WBCS, as their hard work in securing funding for this award was invaluable and continues to make a difference in the fight against breast cancer.”

In addition to leading to additional funding from the National Institutes of Health and other funding organizations, the award also resulted in a valuable collaboration between Dr. Dwinell and Dr. Balaraman Kalyanaraman, a previous recipient of a WBCS grant and Professor and Chair in the Department of Biophysics, Harry R. & Angeline E. Quadracci Professor in Parkinson’s Research, and Founder, Free Radical Research Center at MCW. The joint work between Dr. Dwinell and Dr. Kalyanaraman has resulted in a 2019 SHOWHOUSE for a Cure

grant from the National Cancer Institute, 10 published research papers and several new grant applications.

This research has progressed significantly in the eight years since Dr. Dwinell received the WBCS award. In 2018, patents awarded to the CXCL12 chemokine, as well as several variants that resulted from the studies, were licensed to a biotech start-up company in California. Ongoing work continues to eliminate risks with the technology so that it can be successfully translated to the clinic where it may one day prove useful in the treatment of cancer. The WBCS grant was a true-force multiplier and led to a recent R01 grant from the National Cancer Institute to Dr. Dwinell as well as a separate National Cancer Institute grant to a prior trainee from Dr. Dwinell’s laboratory who is studying ways to inhibit breast cancer progression in his independent laboratory.

Dr. Cui and Dr. Dwinell are just two of the many researchers whose work demonstrates the importance of the support from WBCS. This partnership has helped ensure that world-class breast cancer and prostate cancer research will continue to develop in Milwaukee, Southeast Wisconsin and beyond. This research is both life-supporting and life-changing.

The commitment of WBCS inspires MCW’s researchers to work even harder toward the shared dream to reduce the burden of breast cancer and prostate cancer and to provide patients and families with the hope of a better tomorrow.

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2019 RESEARCH for a Cure 2019 Progress Report from WBCS Professor Hallgeir Rui, MD, PhD As we welcome summer to Wisconsin, I am pleased to provide my annual update on progress focused on breast cancer research at the Medical College of Wisconsin (MCW). During the past year I have had the privilege of serving as the interim co-director of the MCW Cancer Center. This has brought me new perspectives and insights and has also been very gratifying, thanks to the fantastic staff and colleagues at the Cancer Center.

The Cancer Center held its annual scientific retreat at Milwaukee’s Discovery World in April. Dr. Doug Lowy, the acting director of the National Cancer Institute (NCI) gave an inspiring keynote lecture. Progress in breast cancer and prostate cancer research was highlighted at the very successful retreat.

My laboratory continues to apply advanced technologies to measure tumor markers in patient samples, with the goal of matching patients with optimal treatments. Several collaborative publications with Drs. Carmen Bergom and Michael Flister have resulted during the past year. Our MCW oncologist collaborators, including Drs. Lubna Chaudhary, Sailaja Kamaraju, Chris Chitambar, and Yee Chung Chen, lead novel clinical trials for breast cancer patients that will employ our new biomarker technologies, with critical involvement by our breast cancer pathologist Dr. Julie Jorns. Another major effort in our laboratory centers on testing of the drug responsiveness of human breast cancer grown in mice. Our drug efforts are particularly focused on controlling growth of metastases, which cause most breast cancer deaths.

The outstanding colleagues are one of the most stimulating aspects of working at MCW. Many faculty members work on breast cancer or prostate cancer, the focus of research generously supported by WBCS. In addition to the clinician scientists mentioned above, Drs. Carol Williams, Mark McNally, Amit Joshi, Marcelo Bonini, Ben Gantner, Guan Chen, Ling Wang, and Craig Mackinnon are core members of a multidisciplinary and highly collaborative team focused on translational breast cancer research at MCW. Dr. Bonini was awarded a two-year WBCS grant. Dr. Bergom won a prestigious Career Catalyst Award from the Komen Foundation as well as other grants. Dr. Ann Nattinger was awarded a major grant from NCI for her innovative project to identify and reduce use of costly but ineffective breast cancer interventions.

MCW is also fortunate to have a very strong and growing team of researchers focusing on breast cancer disparities, community outreach and population science, including Drs. Melinda Stolley, Joan Neuner, Kirsten Beyer, and Sailaja Kamaraju.

Dr. Stolley published an extensive study in the prestigious Journal of Clinical Oncology, successfully implementing an intervention 18

Hallgeir Rui, MD, PhD

to help 250 African American women make and maintain positive changes in weight, eating habits, physical activity and social support networks. A symposium on breast cancer disparities with an impressive list of internationally recognized speakers was held in early September 2018, an important effort spearheaded by Dr. Kamaraju.

The generous funding raised by the impressively dedicated WBCS leaders and volunteers continues to provide immense support to the thriving breast cancer and prostate cancer research programs at MCW. In turn, investigators allocate spending of the funds wisely and responsibly for maximum research impact. Together, we are translating the hope, optimism, and excitement of discovery into a better future for patients fighting these diseases.

2019 SHOWHOUSE for a Cure

2019 RESEARCH for a Cure Prostate Cancer Center of Excellence (PO-COE) at MCW Cancer Center: A Brief Overview PC-COE Faculty

Pete LaViolette PhD

Matthew Riese MD, PhD

Carmen Bergom MD, PhD

Melinda Stolley PhD

Deepak Kilari MD

Kathryn Bylow MD

Kirsten Beyer PhD, MPH

John Park PhD

Liang Wang MD, PhD

Marja Nevalainen MD, PhD

William See MD

Ken Jacobsohn MD

William Hall MD

Dev Karan PhD

Weigo Cui PhD

Subramaniam Malarkannan, PhD

Demin Wang PhD

Jennifer Doll PhD

Ken Iczkowski MD

A. Craig MacKinnon MD, PhD

Adam Currey MD

John Burfeind MD

One in seven men will face a diagnosis of prostate cancer in their lifetime. According to the American Cancer Society, other than skin cancer, prostate cancer is the most common cancer in men and is the second leading cause of cancer death in men in the US. WBCS supports prostate cancer research to address these alarming statistics.

In the state of Wisconsin, prostate cancer is the second leading cause of cancer related deaths for men and, therefore, a key strategic area for MCWCC to address.

The prostate Cancer Center of Excellence (PC-COE) at MCW Cancer Center harbors a highly active hub of prostate cancer research led by Marja T. Nevalainen, MD, PhD (research) and William A. See, MD (clinical care). The mission of PC-COE is to provide superior clinical care and conduct multidisciplinary research on prostate cancer to improve outcomes in both quantity and quality of life for men affected by prostate cancer and in doing so benefit both prostate cancer patients and their families. The goals of the PC-COE are to increase outstanding collaborative multi-disciplinary prostate cancer research at PC-COE, promote excellence in providing superior clinical care for prostate cancer patients, increase the number of clinical trials offered to prostate cancer patients at MCW Cancer Center, create a distinct training program for the next generation prostate cancer scientists, strengthen fund-raising for prostate cancer research at PC-COE to provide seed funding for new ideas and projects and for fellowships for our trainees, promote community outreach and research to decrease racial disparity in prostate cancer incidence, morbidity and mortality, and achieve/acquire higher name recognition for prostate cancer care and research at MCW within the institution, the state of Wisconsin, and nationally.

2019 SHOWHOUSE for a Cure

Colleen Lawton MD

Marja Nevalainen, MD, PhD, Professor, Department of Pathology/Pharmacology-Toxicology - Using genetic and pharmacological approaches, Dr. Nevalainen provided and validated the proof-of-concept that Stat5 is a therapeutic target in prostate cancer. Using medicinal chemistry, Dr. Nevalainen’s group identified a family of novel small molecule Stat5 inhibitors, which show great promise for further optimization and clinical development. In addition, work from her laboratory brought forth the novel concept that Stat5 is a marker to predict poor clinical outcome of patients treated with radical prostatectomy. Current work focuses on Jak2-Stat5 signaling mediating development of prostate cancer resistance to antiandrogen, enzalutamide (Xstandi), and a clinical trial is currently in preparation at MCW Cancer Center for the efficacy of Jak2 inhibitors for enzalutamide resistant prostate cancers.

William A. See, MD, Professor and Chair, Department of Urology–Oversight of the clinical management of prostate cancer at MCW Cancer Center and facilitation of collaborative efforts for both basic and clinical research efforts, in addition to faculty mentoring.

THERAPY DEVELOPMENT Marja Nevalainen, MD, PhD, Professor, Department of Pathology/Pharmacology-Toxicology - Therapy development for castrate-resistant advanced prostate cancer based on targeting Jak2-Stat5 signaling to be transitioned to clinical development.

Matthew Riese, MD, PhD, Department of Medicine Development of prostate cancer immunotherapies through identification of novel targets on T cells.

Malarkannan Subramanian, PhD, Department of Microbiology – NK-cell-mediated immunotherapy for prostate cancer.

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2019 RESEARCH for a Cure

Continued

William Hall, MD, Department of Radiation Oncology – Research focuses on MR-guided radiation therapy along with the interaction of the immune inflammatory state and response to treatment with radiation therapy in patients with adenocarcinoma of the prostate.

Carmen Bergom, MD/PhD, Department of Radiation Oncology – Research program focuses on both breast cancer and prostate cancer. Her laboratory focuses on identifying factors in tumor cells and the tumor microenvironment that can be targeted to improve the effectiveness of radiation therapy.

Dev Karan, PhD, Department of Pathology - Dr. Karan’s laboratory addresses the role of immune system in antitumor therapy, activation of antitumor responses and characterization of antitumor effector mechanisms specific to prostate cancer.

His laboratory developed a prostate cancer vaccine targeting multiple antigens specific to prostate cancer with an immediate goal to translate this immunotherapy approach into clinics.

DEVELOPMENT OF DIAGNOSTICS Liang Wang, MD, PhD, Department of Pathology/Microbiology - Development of predictive biomarkers for advanced prostate cancer with focus on a non-invasive blood-based genetic test.

Peter LaViolette, PhD, Department of Medical Physics and Imaging Science - Development of prostate cancer diagnostics by improved detection and staging by combining MRI and diagnostic pathology.

Kenneth Iczkowski, MD, Department of Pathology Development of prostate cancer pathology diagnostics with a focus on prostate cancer grading and architectural patterns.

CLINICAL RESEARCH/CLINICAL TRIAL ACTIVITY Colleen Lawton, MD, Department of Radiation Oncology Co-Chair of a clinical trial using radiation and hormone therapy for lymph node positive prostate cancer/ Development of MR LINAC-directed radiation therapy for prostate cancer at MCW Cancer Center.

Kenneth Jacobsohn, MD, Department of Urology Evaluation of clinical management of prostate cancer by robotic surgical techniques and patient outcomes.

Deepak Kilari, MD, Department of Medicine - Biomarker development based on exosomal micro-RNAs in advanced

prostate cancer. Clinical trial evaluating enzalutamide and dutasteride as first-line treatment for advanced prostate cancer.

Kathryn Bylow, MD, Department of Medicine - Geriatric oncologist who is interested in functional outcomes of older patients with cancer. Current research focuses on minimizing toxicities related to androgen deprivation therapy in men being treated for prostate cancer.

PROSTATE CANCER DISPARITIES Dr. Melinda Stolley, PhD, Professor, Department of Medicine and Dr. Staci Young, PhD are currently collecting qualitative data from African American men to understand specific socioeconomic barriers that prevent prostate cancer screening, early detection and treatment. This project partners with key community organizations such as Walnut Way, to generate a line of communication with prostate cancer patients and survivors, as well as men who have not had the disease.

Kirsten Beyer, PhD, Institute for Health & Equity - Dr. Beyer has worked with her team to create maps of prostate cancer incidence, late-stage diagnosis, and mortality in Wisconsin, revealing clear spatial patterns of disparity. In addition, she is currently a consultant on a large project based in California called RESPOND (Research on Prostate Cancer in Men of African Ancestry: Defining the Roles of Genetics, Immunity and Stress).

She will assist in an examination of the relationship between social stressors and prostate cancer aggressiveness.

SUMMARY Improving outcomes for prostate cancer involves research in multiple areas: biology, etiology (causes of cancer), imaging, prevention, early detection, treatment, cancer control, survivorship and outcomes. MCWCC is fortunate to have a fantastic team of prostate cancer scientists. We need to enhance this great team by bringing researchers who focus on clinical trials, or basic research, as well as population health researchers to increase prostate cancer research from multiple angles and to foster translational research. Translational research involves moving findings from the laboratory to our patients and general population as well as findings from the population back to the laboratory. In summary, these findings will help patients in Wisconsin and will also have an impact on prostate cancer nationally.

HOPEFUL TRENDS in Prostate Cancer Treatment There are two very exciting trends taking place in prostate cancer. Both are poised to translate into a net lower burden of therapy for the population of men diagnosed with this disease.

The first of these is the promise of focal therapy. Much as was the case for total mastectomy in breast cancer 30 years ago, removal/treatment of the entire prostate is associated with significant treatment-related morbidity. The development of the 3T MRI, as the equivalent of the mammogram for men, allows the opportunity to identify, target for treatment, and follow clinically significant prostate cancers absent the need to treat the whole organ. Coupled with the existing availability of focal treatment modalities—MRI Linac, high-intensity focused ultrasound, cryoablation, laser ablation—these imaging advances will be transformative in decreasing treatment toxicity.

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A second, somewhat competing approach, focuses on advanced prostate cancer. Over the past decade there have been multiple advances in life extending treatment options for patients with metastatic prostate cancer. The ability to turn metastatic prostate cancer into a chronic disease condition, so as to decrease the contribution of prostate cancer cause-specific mortality to overall mortality could obviate the need to subject men to curative therapies and their associated toxicity. While it sounds heretical, in this setting only the small percentage of men with prostate cancer who progress to the life-threatening metastatic stage would be treated, with the promise that they could undergo therapy at that time and still avoid death from prostate cancer. While very feasible, this latter paradigm is more remote than the proximate promise of focal therapy. William A. See, MD 2019 SHOWHOUSE for a Cure

2019 SHOWHOUSE Dedication mission and purpose. After being diagnosed Linda Short’s introduction to WBCS with breast cancer the year I joined the WBCS and its mission began in 2000 when board, the passion grew even greater. I believe she volunteered as a Showhouse for a the fact that our mission is for both breast Cure docent. In 2001, after retiring from cancer and prostate cancer research is key a 30-year career as a fifth grade inner city to our success.”

Milwaukee Public Schools (MPS) teacher, Linda’s 2007 breast cancer was diagnosed Linda became increasingly involved in following a routine mammogram. She WBCS. She accepted an invitation to join received a call from her doctor saying the films the board in 2007 as public relations were bad. Linda recalled, “He never said the chair, and within a short time assumed C word. I finally asked, ‘Do you mean I have the added the responsibility of volunteer cancer? He replied, ‘Yes, I am afraid you do.’” engagement. Linda’s quiet dedication At first, the implications of hearing the and tireless organizational leadership news didn’t sink in. Then, Linda remembered helps fuel the successful staffing of the her mother had been diagnosed with breast Showhouse and recruitment of hundreds cancer at age 69 and had elected to have a of volunteers annually. Her invaluable Linda Short mastectomy. Despite her mother’s history, back room leadership managing Linda was optimistic about the future. She felt fortunate that her volunteers helps ensure success of the annual WBCS Salute to association with WBCS was the link to knowing about respected Survivors Fashion Show and Luncheon and other events.

Medical College of Wisconsin breast cancer surgeon Dr. Alonzo Whenever there is a task to fill, Linda is first in line to help.

Walker, long an advocate for breast conservation. Because of To say that Linda is “all in” with whatever she does seems an the nature of her diagnosis, Dr. Walker was able to perform understatement. West Bend Mutual Insurance Company a lumpectomy at Froedtert Hospital. Following surgery, she President and CEO and longtime supporter of WBCS Kevin received radiation at Columbia St. Mary’s Hospital Ozaukee [now Steiner expressed it this way about Linda’s spirit and community Ascension Columbia St. Mary’s Hospital Ozaukee]. As it turned activism: “Linda Short is an amazing lady. She is a tireless worker, a out, she said, “I was very blessed to have a smooth walk down giver to many, a survivor, and my friend. Her contributions to the my cancer path.”

Showhouse for a Cure and cancer research are substantial. Our There is an irony to Linda’s story of beating cancer. After five world is a better place because of Linda Short.” years on medication, a routine annual follow-up mammogram A native Wisconsinite, Linda and her two sisters grew up in and ultrasound confirmed the good news that there was no Whitefish Bay. After receiving the Whitefish Bay High School home evidence of cancer. “I was now considered a survivor. I called economics award given to a graduating senior, Linda seemed Carol, my twin sister, to share my joy, only to hear that very day headed to a career in that field. She started college with that she, too, had had a mammogram and ultrasound. Unfortunately, intent at the University of Wisconsin-Stout, but realized her true her news was not good. Because of the challenging diagnosis, calling was in teaching. Her graduation with a Bachelors degree in Carol had to undergo surgery for a double mastectomy.” elementary education from the University of Wisconsin-Milwaukee Carol lives in Orlando and was treated at Florida South was followed by a Masters in elementary education from Hospital, and, hopefully, according to Linda, Carol’s cancer Milwaukee’s Cardinal Stritch University. Asked about her many years seems to be gone. in the classroom, Linda said about the students, With her twin sister’s diagnosis in mind, Linda has strong “I was a teacher, mentor, disciplinarian, friend, and someone they advice for others. “My advice to women is, do not ignore having trusted. Some are still in my life. They all remain in my heart.” your mammogram. We have come a long way in the fight to Although Linda retired from MPS in 2001, she has never really cure cancer. In fact, a simple, even more specific, mammogram retired from working or helping others. Linda summed up the is now a possible option. The fact that it takes time and might be main activities that keep her busy: “I teach water fitness and uncomfortable is no excuse. Finding cancer early, like I did, can senior exercise in Cedarburg, work at a boutique in Cedarburg definitely be a blessing.” and do their fashion shows. I am also a sales representative Linda’s life philosophy is validated by the way she lives her for KP! Toffee. I volunteer at Riveredge Nature Center and for life—from caring for her husband during his course of dementia Interfaith Ozaukee County, giving rides to appointments and at the end of his life to volunteering wherever she sees the grocery shopping for people in need, in addition to being very need to amplifying the success of businesses that employ involved as a WBCS volunteer.” her with enthusiasm and hard work, Linda answers every call.

Technology executive and Trustee of the Frieda and “I truly believe,” said Linda, “God put me on this earth to William Hunt Memorial Trust John Seaman spoke about why give to others.” the Hunt Foundation has supported WBCS in honor of Linda.

For all that she does for others and for answering the call to “Empathy, kindness and true friendship define Linda. She is the arms to improve survival through breast cancer and prostate consummate volunteer and has changed lives for the better in cancer research, WBCS is honored to dedicate its 22nd annual our community and beyond.”

About WBCS, Linda gave insight into why the organization is so Showhouse for a Cure to leadership volunteer, WBCS board important to her, saying, “I so enjoy spreading the word about our member and special friend, Linda Short.

2019 SHOWHOUSE for a Cure

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2019 CHRISTY FOOTE Fighter Award William A. See, MD

It is his passion for excellence in all things that strikes me as the defining quality that has enabled him to build a worldDr. William “Bill” See’s curriculum class department, contribute to greatly vitae reveals a bright line between enhanced urologic care and quality in our his high school wrestling and soccer region and collaborate with the PEOPLE days and his career as a distinguished of MCW to develop outstanding research academic urological oncologist and and clinical PROGRAMS to improve our Medical College of Wisconsin (MCW) Knowledge to Change the Lives of those Department of Urology Professor with prostate cancer.” and Chair. He recalls, “I knew before Another landmark in the history of the attending college that I wanted to be academic medical center involving Dr. See’s a physician. Physicians held positions leadership occurred in 2003. The Medical of respect in society as a consequence College Dean and the President of Froedtert of what I perceived to be the altruistic Hospital jointly established a committee led nature of their profession.”

by Radiation Oncology Professor and Chair A graduate of Coe, a small liberal Dr. J. Frank Wilson, MD to “create a vision arts college in Cedar Rapids, Iowa, for a Froedtert and the Medical College of he earned his MD degree from the Wisconsin Cancer Center.” Looking back, University of Chicago Pritzker School William A. See, MD Dr. See reflected on that initiative: “I am of Medicine, followed by residency extremely proud of the success of the Department of Urology training at the University of Washington School of Medicine and having served as its inaugural Chair. That said, my greatest in Seattle. He capped his training there as Chief Resident in organizational accomplishment was to have played a key role in the the Department of Urology (1987-88), before returning to decision to build the Froedtert Hospital Clinical Cancer Center.” the Midwest. Dr. See chose to specialize in urology because it Dr. Wilson, founding Director of the Cancer Center, echoed “affords a distinct combination of both medical management the importance of Dr. See’s partnership at that fledgling time. “Dr. and surgical practice. Careers in urology can be tailored along See enthusiastically shared and advanced a vision of the Cancer many paths from major body cavity surgery to endoscopic Center that became a reality. His leadership efforts were a key surgery to microsurgery.” element in that regard.”

Dr. See was recruited to the University of Iowa Department Numerous awards span the course of Dr. See’s meritorious of Urology in 1988 as American Foundation for Urologic Disease academic and professional career—a list too long to mention Scholar, Urologic Oncology (1988-1990) and instructor in the here; but, naming just a few gives insight into the importance College of Medicine, rising to the rank of professor in 1996. His of his urologic disease achievements. They include: The Best appointment as Staff Physician at Iowa City Veterans Medical Doctors in America; America’s Top Doctors for Cancer; America’s Center in 1988 became an integral component of his medical Top Urologists; America’s Top Surgeons; and US News and World career. Dr. See observed, “The quality of health care delivery at Report’s “Top Doctors” and “Top Urology Programs.”

VA hospitals affiliated with academic institutions is outstanding. It Behind his many acknowledgments, Dr. See credits his wife is truly patient centered in that the focus is on the management Cynthia as his true partner over the course of his career. “Without that serves the patient’s best interest.” her contributions to managing our lives, I would not have been Opportunity met a prepared mind when Dr. See was recruited able to achieve my professional accomplishments.” He observed, to MCW as Professor and Chief of the Division of Urology in 1999 too, on the critical importance of his colleagues’ commitment and as Chief of Urology at Froedtert Hospital. His appointment in building a renowned urology program, saying, “The heralded a commitment on the part of both institutions to establish establishment and growth of the Department of Urology has regional leadership in prostate cancer and urologic oncology care been a true team effort. Hospital and MCW leadership, together and to develop a prostate cancer disease research center, now with the tireless efforts of the department’s faculty, residents a thriving Prostate Cancer Center of Exellence he co-directs with and staff, have aligned to build one of the pre-eminent urology Marja Nevalainen, MD, PhD, MCW Professor and Eminent Scholar, programs in the country.”

Department of Pathology and Pharmacology/Toxicology.

In accepting his nomination, Dr. See remarked, “I consider As proof of his leadership success, in 2003 the division it a great privilege to work with the membership of WBCS in was given departmental status and Dr. See was appointed to advancing the clinical and basic science of caring for patients with his current role as inaugural Professor and Chair of the newly breast cancer and prostate cancer. In the context of the work formed Department of Urology. In 2005, he also assumed the your organization performs, I am humbled to receive this award.” additional role of Chief of Urology at the Zablocki VA Medical In turn, WBCS is honored to present its sixth annual Christy Center, Wood, Wisconsin.

Foote Fighter Award to William A. See, MD to recognize his MCW Provost and Executive Vice President and Dean of storied local, national and international contributions to defeat the School of Medicine, Joseph E. Kerschner, MD commented, urologic diseases and for his tireless efforts to advance prostate “I have been privileged to work with Bill for much of his MCW cancer research and treatment. tenure in our various leadership roles in the School of Medicine.

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2019 SHOWHOUSE for a Cure

HOPE has a home

The 2019 Wisconsin Breast Cancer Showhouse History The location of the 2019 Wisconsin Breast Cancer Showhouse at 161 West Wisconsin Avenue, Milwaukee is on the site of John Plankinton’s original Plankinton House Hotel. Subsequently, on the site, The Plankinton Arcade was built with its sweeping staircases, lofty skylights, and its distinctive symbol, the quatrefoil, representing a flower with four petals, or a clover. The Showhouse’s seven apartments, located in Plankinton Clover on the Arcade’s second level, merge the rich heritage of The Plankinton Arcade with The Avenue’s current needs and future dreams.

The Milwaukee John Plankinton story begins in 1844 when 24-year old John Plankinton, his wife, Elizabeth, and their infant son, William, moved to the Wisconsin Territory two years before Milwaukee was incorporated as a city. Plankinton, a butcher, rented a lot on the current site of the ASQ building on what was then known as West Water Street. He bought a cow for $9 and started selling fresh meat across the street from the American House Hotel. Having great success with his meat business, Plankinton began operating a retail business, living above it, and investing in real estate. He continued to buy large parcels of land on West Water Street and Spring Street, now Plankinton and Wisconsin Avenues.

The location of West Water Street was strategic to Plankinton’s meat packing and retail businesses by providing access between Milwaukee and Chicago via stagecoach, railroad and water. During the course of his meat packing business, Plankinton had several partners, Frederick Layton, Phillip Armour, and Patrick Cudahy.

The Plankinton & Armour Company expanded to Chicago, Kansas City, and New York and grossed $15 million in 1880. In 1884 it officially broke up. Patrick Cudahy then became Plankinton’s superintendent and business partner. In 1888 Plankinton’s health deteriorated and a major portion of the business was acquired by Patrick Cudahy and John Cudahy, Patrick’s brother.

Plankinton was married twice. He and his first wife, Elizabeth, had a son, William, and two daughters, Elizabeth and Hannah.

Hannah died at age 17. The family moved to Spring Street after Plankinton purchased an existing mansion there and spent $200,000 remodeling it, making it the most elegant and expensive home in the city. Adjacent to his five-acre estate, Plankinton built an Edward Townsend Mix mansion for his son. When his daughter Elizabeth became engaged to Richard Henry Park, she was given a mansion as a wedding present. However, Mr. Park abruptly married another women. Elizabeth never lived in the house and only visited it once. She eventually bequeathed it to the Knights of Columbus, and the Knights deeded it to Marquette University.

The house was razed in 1980 after much controversy. With the dawning of so many opulent and luxurious homes of Milwaukee’s wealthy beer barons and industrialists on Spring Street, the street was renamed Grand Avenue.

Kay Brogelman Showhouse Historian 2019 SHOWHOUSE for a Cure

continued on page 43

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BOHO CHIC...

FROM BLUSH TO BASHFUL Living Room ~ Apartment 249

Ken Michaels Furniture / Michael Carter Design Michael Carter Assisted by Praveena Wikramanayake Ken Michael Furniture, 18525 W. Capitol Drive, Brookfield, WI 53045 Ken Michaels Furniture Brookfield – 262.781.3850 Michael Carter – 262.305.4331 brookfield@kenmichaelsfurniture.com michael@michaelcarterdesign.com www.kenmichaelsfurniture.com www.michaelcarterdesign.com

The inspiration for this space started with a love of a fabric; the deep color, the vibrancy, the texture, the fabric on the swivel chair was my start. From that I thought who might live here and this late 20s/ early 30s woman came to life. She worked hard to prove herself and get where she is. She proudly embraces her feminism without compromising her femininity. She is a grown woman and owns “pink” as her signature color. Just as Julia Roberts said in Steel Magnolias, “My colors are not pink and pink, mama. My colors are blush and bashful”. Instead of a broad color palette used often in Boho looks, I stuck to the values of pink tones for my color story. To help carry the color story, grays, blacks and creams were also used, plus metallics ranging from gold to champagneto silver. As is tradition, Boho uses animals as a theme. Instead of real antlers or hanging a mounted skull on the wall, I used candle holders shaped like antlers. I also love bird references, so they are incorporated throughout including as a focal point, the decals on the pole as you enter, changing the eyesore into a center of attention.

Plants are also important in Boho designs. On the walls, oversized peony decals act to soften the lines of the seating space and bring focus down to the seating group. It’s a great, new option renters should consider to personalize temporary spaces. n

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2019 SHOWHOUSE for a Cure

URBAN RETREAT Bedroom & Bath ~ Apartment 249

G.Home Laura Goranson Heather Weber Connie Gilsinger & Elizabeth Rennicke 1135 Legion Drive, Elm Grove, WI 53122 262.788.9601 414.704.6075 laura@ghomestore.com www.ghomestore.com

Inspired by an urban lifestyle ever-present in downtown Milwaukee, the space encompasses a sense of warmth and coziness in a bustling city setting.

The bedroom is a retreat filled with calming aromas, touches of nature and beautiful textures throughout. We added pops of color in the closet to create a space where people can express their unique style and have a distinctive space to get ready in. As with the bedroom, the goal for the bathroom was a welcoming retreat.

We chose a black and white theme with touches of gold accents to continue a modern feel with playful, glam elements.

G. HOME is a locally owned retail shop and design center in Elm Grove. We offer custom furnishings, decor and gifts, with a passion for helping our customers find the perfect elements to fit their own unique style. n

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LIVING ROOM Apartment 248

Nicholas Carl Design Inc. Nicholas Carl Konzal 414.510.3449 nkonzal@gmail.com www.nicholascarldesign.com

My design was inspired by the active and vibrant city around the apartment.

The proximity to the theatre and other cultural activities lead me to imagine a colorful, fun and playful interior filled with art and life.

CREDITS Finishes of Design – Wallcovering Installation Chuck 414.840.4888 n

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2019 SHOWHOUSE for a Cure

BEDROOM Apartment 248

Bachman Furniture Joe Bachman 1741 W. St. Paul Avenue Milwaukee, WI 53233 414.461.9000 joe@bachmanfurniture.com www.bachmanfurniture.com

I was inspired by recent international travel and European design.

Carefully curated smaller spaces still allow for high design.

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BATH Apartment 248

Nicholas Carl Design Inc. Nicholas Carl Konzal 414.510.3449 nkonzal@gmail.com www.nicholascarldesign.com

My design was inspired by the active and vibrant city around the apartment.

The proximity to the theatre and other cultural activities lead me to imagine a colorful, fun and playful interior filled with art and life.

CREDITS Finishes of Design – Wallcovering Installation Chuck 414.840.4888 n

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2019 SHOWHOUSE for a Cure

ARTIST’S RETREAT Apartment 247

Haven Interiors Karen Sullivan 1457 North Farwell Avenue Milwaukee WI 53202 414.765.2350 karen@haveninteriorsltd.com www.haveninteriorsltd.com

As soon as I walked into the apartment, I felt those vast walls longed for art!

I’m thrilled to have followed through on that vision and to make the living space an artist’s home away from the studio.

I was pleased when Carrie Chimenti was so quickly on board to help with that! Chimenti’s backsplash in the kitchen is an homage to Milwaukee with the graphic based on the Marquette Interchange and the logo from our city flag. It’s so apropos to have an artist’s interpretation!

CREDITS WALL FINISHES/PAINT Chimenti Studios Carrie Chimenti 262.573.1061 Chimentistudios@gmail.com www.chimentiStudios.com CDS Installation for Art Installation Company Contact: Dan Johnson Email: cdsinstall@centurytel.net n

2019 SHOWHOUSE for a Cure

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BEDROOM Apartment 247

Suzan J Designs Suzan Wemlinger Lisa Gramoll 608 N. Broadway, Milwaukee WI 53202 414.967.1992 414.467.3350 suzan@suzanjdesigns.com www.suzanjdesigns.com

I imagined that a young professional artist lives here, and her bedroom reflects that. She enjoys art in different mediums, and also likes to display and collect art from her fellow artist friends.

Her eclectic bedroom is her sanctuary, and where she feels most creative.

CREDITS WALLPAPER York Wallcoverings www.yorkwallcoverings.com WALLPAPER INSTALLER Mary Grundle 414-467-8067 BED, CHAIR, TABLES, TEXTILES, ART & CUSTOM GREENS Suzan J Designs 414.967.1992 info@suzanjdesigns.com www.suzanjdesigns.com POP ART – FIGHT LIKE A GIRL Pius XI Emerging Artists PHOTO OF BEARDED MAN Jay Filter 414.315.1235 www.jayfilterphotography.com PHOTO OF GIRL WITH PIXIE CUT JMZ Photo 414.659.9187 www.jmzphoto.com n

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2019 SHOWHOUSE for a Cure

BATHROOM Apartment 247

Alexandra Wood Design Alexandra Wood 847.732.4384 awood1226@gmail.com www.alexandrawooddesign.com Instagram: @alexandrawooddesign

It’s all about the layering of little details and mixing old with new in this bathroom.

Art, fabric, linens, and bath accessories are key elements of the design. The end result is a feminine and chic bathroom that will remain timeless and classic.

CREDITS Schumacher To the Trade Only www.fschumacher.com Stark Carpet To the Trade Only www.starkcarpet.com Hook and Knob paul@hookandknob.net www.hookandknob.net Monica Hees, Artist monicahees78@gmail.com Chairish 855.549.9990 www.chairish.com n

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TRUNK FULL OF MEMORIES Living Room, Kitchen & Foyer ~ Apartment 246

Fringe Interior Design & Home Furnishings Jessica N Bertoni 133 E. Silver Spring Drive Whitefish Bay, WI 53217 414.332.0400 bertoni@fringeinteriordesign.com www.fringeinteriordesign.com

Elephants are amazing animals; highly social, incredibly intelligent and led by matriarchs of their herds - revolutionaries before their time! These beautiful creatures call some of the most exotic places on earth home, and they provided strong inspiration for the spaces in this home. The foyer opens into an expansive space with plenty of room to roam, socialize or retreat quietly with a book. The accents are drawn from nature, and the furnishings compose a base of welltraveled comfort to help you feel at home in your urban surroundings. Rugs throughout the apartment are tribal, featuring linear patterns that merge rich jewel toned color and a modern design perspective.

The layout is harmoniously designed for comfort and efficiency: you can grab a spot on the social sofa to chat with your friends at the kitchen island, or you can gather around the inverted pyramid shaped coffee table to look at old photos, plan your next vacation or play a board game.

CREDITS Persian Rug Gallery Hamid Dehbod 159 E. Silver Spring Drive, Whitefish Bay, WI 53217 414.964.7847 persianrug-gallery.com ABC Kortsch 2403 N. Maryland Avenue, Milwaukee, WI 53211 414.276.9990 www.kortschmoving.com n

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2019 SHOWHOUSE for a Cure

BE R-ELEPHANT Bedroom & Bathroom Apartment 246

Fringe Interior Design & Home Furnishings Jessica N Bertoni 133 E. Silver Spring Drive Whitefish Bay, WI 53217 414.332.0400 bertoni@fringeinteriordesign.com www.fringeinteriordesign.com

The bedroom is the pinnacle of luxury; a lavish custom cocoon canopy surrounds the bed creating a sanctuary that encourages restful sleep. Sleek nightstands, gold lamps and in the the corner - a reading nook nestled against natural cork wallpaper with just the tiniest metallic flecks sparkling through for a hint of glam, striking a blend of natural and elegant materials at play. The art over the bed was the inspiration for the space featuring a stunning woman exhibiting strength a matriarchal leader no doubt. The bathroom and closet feature richly layered pieces to get you up and out of the house with a smile on your face–perhaps that’s because you’ve got a “friend” to greet you in the shower?!

What’s not to like about that?

CREDITS Mary Johnson Grundle 414.467.8067 mjgwallpaper@yahoo.com ABC Kortsch 2403 N. Maryland Avenue, Milwaukee, WI 53211 414.276.9990 Website: kortschmoving.com In’spie(r) To The Trade Persian Rug Gallery Hamid Dehbod 159 E. Silver Spring Drive, Whitefish Bay, WI 53217 414.964.7847 persianrug-gallery.com CDS Window Treatment Installation Dan Johnson To the Trade n

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STUDIO 245 Living Space ~ Apartment 245

Residence Interiors Kerry Dean Shannon Michael Patrick McKinley Kimberly Hunter Streater Lindsey L. Duba/MATC Marissa Moeser/MATC 123 East Wells Street Milwaukee, WI 53202 414.444.5010 414.731.7296 Kerry@residencemilwaukee.com www.ResidenceMilwaukee.com

Following in the footsteps of the late Billy Baldwin, we have imagined Apartment #245 as the Interior Design Studio and pied-a’-terre of a busy and talented interior designer with a decidely urban clientele. The Studio offers a rich variety of wallcoverings and textiles set amidst a sophisticated color palette while the living space allows entertaining surrounded by a collected blend of style, color, texture and pattern.

CREDITS Uncommon Walls Betsy Peckenpaugh 414.315.2587 bbenpeck@icloud.com Leonard Fine Art Gary Leonard 414.659.3804 Gary@leonardfineart.com www.Leonardfineart.com Madeline Peckenpaugh Madelinepeckenpaugh@gmail.com Elements East Meg Hopkins 191 North Broadway Milwaukee, WI 53202 414.488.9767 info@elementseast.com www.elementseast.com Mike Zei Painting and Drywall Mike Zei 1660 North Prospect Avenue 262.880.9006 Shabahang Rug Gallery Bezhad Shabahang www.rugsbyshabahang.com

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Lake Country Window Fashions Nancy Showers 262.490.0099 nancy.lcwf@gmail.com Sew Sensational Jenny Corona.

262.758.7779 Village Paint & Design Becky Maercklein 845 N. Mayfair Road 414.988.8296 Mayfair.paint@villageace.com www.villagepaintanddesign.com Jaimer's Floral Jamie Beauchamp 414.243.0197 Jamie@jaimersfloral.com www.Jainmersfloral.com n

2019 SHOWHOUSE for a Cure

STUDIO 245 Living Space ~ Apartment 245

Residence Interiors Kerry Dean Shannon Michael Patrick McKinley Kimberly Hunter Streater Lindsey L. Duba/MATC Marissa Moeser/MATC 123 East Wells Street Milwaukee, WI 53202 414.444.5010 414.731.7296 Kerry@residencemilwaukee.com www.ResidenceMilwaukee.com

Following in the footsteps of the late Billy Baldwin, we have imagined Apartment #245 as the Interior Design Studio and pied-a’-terre of a busy and talented interior designer with a decidely urban clientele. The Studio offers a rich variety of wallcoverings and textiles set amidst a sophisticated color palette while the living space allows entertaining surrounded by a collected blend of style, color, texture and pattern.

CREDITS Uncommon Walls Betsy Peckenpaugh 414.315.2587 bbenpeck@icloud.com Leonard Fine Art Gary Leonard 414.659.3804 Gary@leonardfineart.com www.Leonardfineart.com Madeline Peckenpaugh Madelinepeckenpaugh@gmail.com Elements East Meg Hopkins 191 North Broadway Milwaukee, WI 53202 414.488.9767 info@elementseast.com www.elementseast.com Mike Zei Painting and Drywall Mike Zei 1660 North Prospect Avenue 262.880.9006 Shabahang Rug Gallery Bezhad Shabahang www.rugsbyshabahang.com

2019 SHOWHOUSE for a Cure

Lake Country Window Fashions Nancy Showers 262.490.0099 nancy.lcwf@gmail.com Sew Sensational Jenny Corona.

262.758.7779 Village Paint & Design Becky Maercklein 845 N. Mayfair Road 414.988.8296 Mayfair.paint@villageace.com www.villagepaintanddesign.com Jaimer's Floral Jamie Beauchamp 414.243.0197 Jamie@jaimersfloral.com www.Jainmersfloral.com n

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DAPPER DAN’S WARDROBE Apartment 245

Ivy Interiors Patty Virnig Claudia Gavery 19185 Alta Vista Drive, Brookfield, WI 53045 262.784.8535 Ivyinteriorspatty@hotmail.com

The art work of the young well-dressed, “dapper” man was our inspiration.

CREDITS Mike Zei Painting Mike Zei 262.880.9006 n

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2019 SHOWHOUSE for a Cure

BATHROOM Apartment 245

Elements East Meg Hopkins Julie Zvi 191 N. Broadway, Milwaukee Wi 53202 414.488.9767 Julie Zvi: 414.708.1718 mhopkins@elementseast.com JulieZvidesigns@elementseast.com www.elementseast.com

At Elements East we believe in the mix: of old and new, East meets West, modern and antique. Our recent trip to Morocco reinforced this idea. Our bathroom incorporates pieces from both Asia as well as China. We love how they mix together into a modern, dramatic, and hopefully a little unexpected, bathroom.

CREDITS T & L Glass Service 5678 N. Green Bay Road, Milwaukee, WI 53209 Doug Wenzel Wallpaper Doug Wenzel W235N8711 Woodside Road, Sussex, WI 53089 Giraffe Electric Jeff Jrolf 2025 S. West Avenue, Waukesha, WI 53189 262.549.6500 jeff@giraffeelectric.com Shabahang & Sons Gallery of Fine Rugs Bezhad Shabahang 601 E. Ogden Avenue, Milwaukee, WI 53202 414.347.1300 shabahang@ameritech.net ww.rugsbyshabahang.com Artist Group (Moroccan photographs) Katy Rowe 414.208.7744 info@artistgroup.net www.artistgroup.com

2019 SHOWHOUSE for a Cure

The Finial Coleen 7555 W. Mequon Road, Mequon, WI 53092 262.242.9335 TheFinial@sbcglobal.net Kathryn Isbister (“Lady In Pearls� Encaustic Artwork) Kathryn Isbister kaisbister@gmail.com www.chatseye.com n

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“ABODE TO JOY�

Apartment 244

Ethan Allen Alvin Heitmann Nancy McMahon 425 N. Moorland Road, Brookfield WI 53005 262.797.6872 alvin.heitmann@ethanallen.com nancy.mcmahon@ethanallen.com www.ethanallen.com

A classic pied-a-terre. The joy of color and the feel of living in your favorite gallery or museum wing. Effortless and easy.

CREDITS The Susan Company Susan Johnson 414.384.7113 n

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2019 SHOWHOUSE for a Cure

BEDROOM Apartment 244

The Home Market LLC Kate Kazlo 309 North Water Street, Milwaukee, WI 53202 414.755.2165 info@homemarketmilwaukee.com www.shophomemarket.com

I designed this guest room to be a relaxing oasis of sophistication and comfort. I choose a neutral aesthetic with various textures, prints and finishes to create a tranquil and inviting space. The bed is upholstered in a warm linen and is paired with layered soft bedding. The nightstands are a gray washed reclaimed wood paired with slightly darker gray lamps to create contrast with the lighter bed. I used a gray metal sitting bench at the end of the bed to be used as a place for guests to sit or place their luggage.

I added a hint of color to the room with fringed blueish/gray pillows, landscape artwork and refined wallcovering. n

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BRONZE BEDROOM Apartment 244

Modern Health and Living Amanda Lewis W82N915 Stony Kettle Drive, Cedarburg WI 53012.

414.659.6705 amanda@modernhealthandliving.com www.modernhealthandliving.com/homedesign

The temporary wallpaper is apartment friendly and inspired the room itself.

Throughout the room you will see a mix of metallic and metals. A platform storage bed creates a simple modern base that has massive storage, which is a must have for city living. The large wall print over the bed is where the inspiration of adding teal, and greens and mint for accent colors. Crisp white bedding keeps things clean. Nesting tables and a gold and white nightstand, gives storage and a designer touch on each side of the bed. “Seeds� from Wall Play, do make this wall art as playful as the name and a black bamboo stool to add an extra whimsical seating area. Contemporary lighting to complete this urban look.

CREDITS Wallpaper/ Tempaper 732.920.2654 Info@tempaperdesigns.com www.tempaperdesigns.com Prints / MInted www.minted.com Framing / The Great Frame Up Mequon 1400 W. Mequon Rpad, Mequon, WI 53092 262.241.8679 www.mequon.thegreatframeup.com Gold Mirrors / Gold Bamboo Tables / Bee Pillow Zuo Modern www.zuomod.com Wall Decor/ WallPlay The Work Room.

4508 N. Oakland Avenue, Shorewood, WI 53211 amy@theworkroom-milwaukee.com www.theworkroom-milwaukee.com

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Bed/DHP Furniture 800.267.1739 cs@dhpfurniture.com www.dhpfurniture.com Nightstand/World Market www.worldmarket.com Bedding/Bed Bath and Beyond www.bedbathandbeyond.com Throw Blanket/Safavieh www.safaviehhome.com Lumbar Pillow www.jaipurliving.com Mattress www.Verlo.com Clocks/bamboo stool www.containerstore.com Lights/Adesso Home www.Adessohome.com n

2019 SHOWHOUSE for a Cure

STUDIO APARTMENT Living Space ~ Apartment 243

Calico / Uncommon Walls Margaret Weis / Calico Betsy Peckenpaugh / Uncommon Wallsx 18525 Bluemound Road, Brookfield, WI 53045 262.786.4646 calicobrookfield@gmail.com

We're inspired by color, architectural style, and the challenges of designing a small space.

CREDITS Artwork / Madeline Peckenpaugh MadelinePeckenpaugh@gmail.com Artwork / Uncommon Walls Betsy Benes Peckenpaugh 411 South Hawley Road, Milwaukee, WI 53214 414.315.2587 bbenpeck@icloud.com Artwork / C.W. Peckenpaugh peckenpaugh@sbcglobal.net Artwork / Virginia Peckenpaugh VPpattern@gmail.com J.T. Upholstery TheFactory@wi.rr.com Paint / Benjamin Moore n

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STUDIO APARTMENT Bedroom & Bathroom Apartment 243

Calico / Uncommon Walls Margaret Weis / Calico Betsy Peckenpaugh / Uncommon Walls 18525 Bluemound Road, Brookfield, WI 53045 262.786.4646 calicobrookfield@gmail.com

We're inspired by color, architectural style, and the challenges of designing a small space.

CREDITS Artwork / Madeline Peckenpaugh MadelinePeckenpaugh@gmail.com Artwork / Uncommon Walls Betsy Benes Peckenpaugh 411 South Hawley Road, Milwaukee, WI 53214 414.315.2587 bbenpeck@icloud.com Artwork / C.W. Peckenpaugh peckenpaugh@sbcglobal.net Artwork / Virginia Peckenpaugh VPpattern@gmail.com J.T. Upholstery TheFactory@wi.rr.com Paint / Benjamin Moore n

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2019 SHOWHOUSE for a Cure

HOPE has a home continued from page 23 In 1926 over the objections of the merchants of Grand Avenue, the street was renamed Wisconsin Avenue.

In 1867, looking for a hobby and to accommodate business travelers, Mr. Plankinton built a five-story hotel on the site of the former American House Hotel, which had burned down.

Plankinton constructed the hotel in the French Renaissance architectural style with fire-proof materials of sandstone blocks and bricks. No expense was spared. Using local materials and craftsman, his goal was to make it a first-class hotel, grand and opulent. At a cost of $150,000, it was furnished with electric lighting, had a dining room which could seat 300 people, and guestrooms for 600. General Douglas McArthur lived in the hotel in 1897-98 with his mother while attending West Division High School, now Milwaukee High School of the Arts. General McArthur also spent time in the hotel preparing for the entrance exam to West Point. After almost 50 years of existence, the original Plankinton House Hotel was torn down in 1915.

John Plankinton died in his home in 1891, surrounded by his second wife Anna, his son William, and his daughter Elizabeth. He is buried in Forest Home Cemetery. He was hailed as Milwaukee’s foremost citizen and known as an astute businessman with a generous public spirit. His philanthropy included funding for the building of Milwaukee’s first public library, donating land and funds for the construction of the Perseverance Presbyterian Church and providing a rent-free building for a soup-house kitchen funded with a generous amount of money and stocked with a daily supply of meat.

At the time, The Plankinton House Hotel was the largest employer of African-Americans in Milwaukee, many of whom were former slaves. The head waiter, John J. Miles and the second waiter, Benjamin Taylor, both of whom were African-Americans, were pallbearers at Mr. Plankinton’s funeral. Mr. Miles, at the bequest of Mr. Plankinton, is also buried at Forest Home Cemetery.

The Plankinton family wasted no time in planning a Europeanstyle shopping arcade for the site of the Plankinton House Hotel.

The Family employed the prestigious Chicago architectural firm of Holabird and Roche. The Plankinton Arcade was originally two stories, providing over 100 retail shops, and was constructed at the cost of $2.5 million. In 1924, five more stories of professional offices were added to the Arcade, circling the glass ceiling, at a cost of $1.5 million. Again Holabird and Roche were commissioned to do the architectural work. The Arcade was the forerunner of today’s enclosed shopping mall with one structure housing numerous independent shops focused on an interior circulation area.

Architecturally, the Arcade is a blend of 15th Century Italian Gothic detailing on the first two floors, while a Renaissance motif represents the upper stories. It is a smaller replica of a 19th century shopping arcade located in Milan, Italy. The exterior of the Arcade is framed in steel and clad with white-glazed terra cotta, sometimes referred to as “baked earth”. Gracing the interior of the building are terra cotta tiles, grillwork, ornamental intricacies and a glass-domed rotunda. The arched skylights are supported by exposed structural steel arches. During the hot summer months, the glass ceiling could be opened with gears and pulleys to let hot air out while the cool air in the lower level would circulate to “air condition” the main floors. Hand-molded rosettes can be found immediately below the railing of the 2019 SHOWHOUSE for a Cure

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PAST WISCONSIN Breast Cancer Showhouses

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2019 SHOWHOUSE for a Cure

HOPE has a home continued second floor balcony and around the outside of the rotunda.

The elevator shafts on each end of the Arcade display Gothic tracery. Toward the top of the shafts is ornamentation of swags, pediments and finials. At the base of the rotunda, a series of four graceful marble stairways featuring terra cotta balusters and decorative iron elements leads to the lower level.

Over time, much of the ornamentation in the rotunda had suffered water damage and has been restored in terra cotta and plaster. The damaged tiles covered the columns on the edge of the Arcade and have been replaced with new tiles cast by the only remaining terra cotta factory in the United States outside of Sacramento, California. The capitals have been restored in the original pattern of acanthus leaves and the light plate covers above the columns have been recast.

The lower level was the site of “the largest and finest amusement parlor in the world.� Among the attractions were a fish pond, billiard parlor with 60 tables, 41 bowling lanes, a barber shop with 24 barber chairs, a beauty parlor and a Turkish bath. A 75 footmahogany soft drink bar seated over 1,000 patrons a day. Three restaurants accommodated dining guests, The Red Room, The Green Room, and a restaurant in the billiard parlor. A non-stop orchestra completed the entertainment aspect of the complex.

The Red Room Cocktail Lounge featured an up-and-coming piano player named Walter Busterkeys, later known as Liberace.

A bronze statue of John Plankinton that was moved from the

2019 SHOWHOUSE for a Cure

original Plankinton House now stands in the center of the Rotunda set in a tiered fountain covered with whimsical frogs and turtles.

The quatrefoil, a design originally found in medieval ecclesiastical architecture, can be found in many areas of the Arcade, on railings, grillwork and terra cotta tiles. The quatrefoil represents a four-petal flower in the 15th century Italian Gothic and Renaissance design of the Arcade. Wrought iron tracery on the elevator shafts features the quatrefoil and its three sided relative, the trefoil.

The quatrefoil also represents the spirit of a bygone era as

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2019 GIVE-BACK Opportunities Benefit the Wisconsin Breast Cancer Showhouse. When you enjoy lunch, dinner or a snack, these businesses will give back to the WBCS.

café 1505 Eat Local

Jack Pandls WHITEFISH BAY INN

Help us fight breast cancer and prostate cancer.

From June 1st - June 16th, bring in this book and we will donate 20% of your purchase to the WBCS.

CAFÉ CARES

(community activity responsibility)

You Dine, We Donate.

Bring your Showhouse program and we will donate 20% of your check back to the cause.

Our goal is to give all that we can, with as much excitement and vigor as possible, to as many important causes, because we can. Because we should.

www.cafe1505.com 46

Private Parties are Welcome at Pandl’s Bridal Showers Baby Showers Corporate Events Funeral Gatherings Call us today to help make your special occasion a memorable one!

1319 East Henry Clay Street Whitefish Bay, Wisconsin 53217 (at the corner of Lake Drive) 414.964.3800 2019 SHOWHOUSE for a Cure

HOPE has a home continued well as the grandeur of the current Arcade. It characterizes the joining of Milwaukee’s past to its future. Currently, the quatrefoil is reflected in the name of the collection of apartments in The Avenue, Plankinton Clover, which are featured as the 2019 Wisconsin Breast Cancer Showhouse.

The Arcade and downtown Milwaukee’s economic health started to decline in the post-war years. The Red Room and Green Room both closed in 1960. With retail business to the shops declining, the professional offices moving to the suburbs, and the lower level being replaced with game-room like attractions, the City of Milwaukee and Mayor Henry Maier launched a large civic revitalization effort to develop a resurgence of Milwaukee’s downtown, which included the Arcade. .In 1973, The Milwaukee Redevelopment Corporation was organized to focus on Milwaukee’s central business district and the Rouse Management group from Minneapolis was hired to conduct a feasibility study. Their planned development encompassed four city blocks, including Boston Store on the west and Gimbels on the east as anchors, and three historic buildings in between, Plankinton Arcade, Woolworth Building, and the Majestic Building. ELS Design group from Berkeley, California was commissioned to design the structure.

The resulting plan was implemented in 1980 and completed in 1982. The adjacent second Plankinton Hotel, which had been built in 1915 to replace John Plankinton’s original hotel, was torn down to create space for a parking structure for the Grand Avenue complex. The Arcade was connected to Gimbels and to the buildings across Second Street via skywalks. From Second Street to the Boston Store, a third-level food court, The Speisegarten, was created in the former space of the Schlitz Palm Garden. With over 20 vendors, any palette could be satisfied with food options ranging from egg rolls to lamb gyros to pizza.

Professor Stein, the Wunderbear, rode his unicycle over the Grand Court. The Professor can now be found in Milwaukee’s Public Market in the Third Ward above the south entrance.

Smaller shops on the second level lined the Arcade and the New Arcade. Two large central areas provided for plantings, fountains, natural light and seating. The lower level of the Arcade become home to The International Clown Hall of Fame, Patricia Stevens Finishing School, USO Milwaukee, and other small businesses.

On Thursday, August 26, 1982, the Grand Opening of The Grand Avenue took place. Starting with a parade, the all-day affair of musical entertainment of all genres, saluted Milwaukee with the grandest of openings. The Sneak-A-Peek Gala, benefiting local civic and cultural organizations, was held the previous evening. Several thousand people paid $25 each to roam freely through the Arcades and celebrate a toast with friends to Milwaukee’s new upscale shopping experience.

The 1980s and early 1990s found The Grand Avenue’s 845,000 square feet of retail space to be at nearly 100% capacity. Daly’s Pen Shop, Goldi’s, Brills, and other local stores were joined by national chains such as Laura Ashley and a safari-like decorated Banana Republic.

The seven newly-constructed apartments located on the second level of the Plankinton Arcade, now featured as the 2019 Wisconsin Breast Cancer Showhouse, were originally the retail spaces for Material Stuff, Door County Confectionery, Hammonds 2019 SHOWHOUSE for a Cure

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The Friends of Villa Terrace invite you for an evening of cocktails, dinner and dancing in the garden of Villa Terrace honoring Wade Weissmann.

Please visit www.galainthegarden.com for details.

DESIGNER

Give-Back _Program Purchase from one of the participating designers during the run of the Showhouse, and a portion of the sale will be donated to the 2019 Showhouse for a Cure.

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2019 SHOWHOUSE for a Cure

HOPE has a home continued Piano Gallery, Brown Photo, Grand Avenue News, Ashby’s, the Earring Tree, Accessory Lady and Alan Preuss Florists. This year’s Showhouse consists of one studio apartment, one two-bedroom apartment, and five one-bedroom apartments, with square footage ranging from 785 square feet to 1,550-square-feet.

In the early 1990s Milwaukee’s manufacturing economy began to erode, and along with it, high unemployment occurred.

Vacancies in the Grand Avenue skyrocketed and Marshall Field’s, formerly Gimbels, closed in 1997. Soon after The Nature Company, Godiva Chocolatier, Warner Brothers Studio Store, and the ever-popular The Puzzle Box left. The food court and Boston Store remained strong.

By 2002 The Grand Avenue was on life support. Mayor John Norquist and the City Council invested funds to start a revitalization and hopes were high. The entrance was given a face lift and The Grand Avenue was renamed The Shops of Grand Avenue. The surrounding downtown area saw an influx of new residents in restored apartments. Plans were made for a Sheraton Hotel behind Boston Store. The Midwest Express Convention Center opened and the Third Ward was experiencing a major revival. The Marshall Field’s building had been sold to a local group and redeveloped into Borders Book Store, a Residence Inn and the new site for the ASQ Center. The Shops of Grand Avenue were updated with brightly-colored walls, lots of granite, and interior lighting. The YMCA and the University of Wisconsin-Milwaukee Extension moved to the 5th and 6th floors of the Arcade and new tenants leased space on other floors.

The Boston Store underwent renovation that included loft-style apartments above the store. New major retailers, TJ Maxx, Linens ’n Things, Old Navy, and Office Max, moved into reconfigured spaces. With 80,000 office workers downtown, The Shops and food court continued to be viable for a few more years.

In 2005, a New York based company bought The Shops of Grand Avenue. By 2009, Linens ‘n Things had vacated. In 2012, The Shops went into foreclosure and was purchased by a New York firm. After struggling to improve performance, The Shops of Grand Avenue were sold to an investment group in December, 2015 and in April, 2016, the group revealed its redevelopment concept.

On December 6, 2018, The Shops of Grand Avenue became “The Avenue”. Both the east and west spaces of The Avenue will be reconfigured. The 3rd-floor food court will become office space for Graef USA and a new food hall, “The 3rd Street Market Hall” will be constructed on the ground level. A grocery store and open-concept office space is also part of the plan. A portion of the Arcade will become apartments. Milwaukee’s BID district will relocate to new offices in The Avenue and a child care center is in the early stages of discussion. New elevators and stairways will be upgraded. The City of Milwaukee will contribute $3 million to remove the glass vestibule at the front entrance and create a new front door and a wide welcoming plaza with public access.

With access to The Milwaukee Center via skywalks, a birds-eye view of Milwaukee Symphony Orchestra’s renovated historic Warner Grand Theatre into new performing and office spaces, and with the addition of the Fiserv Forum and public plaza and The Hop downtown, The Avenue is ready to spearhead Milwaukee’s central business district renaissance.

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live in style, your style. haven interiors haven

H

Ansay

& ASSOCIATES Insurance & Benefit Solution

1457 N. Farwell Avenue Milwaukee, WI 53202 414.765.2350 15 S. 3rd Street Geneva, Il 60134 630.402.0444

PO Box 7, Cedarburg, WI 53012 262.377.2000

haveninteriorsltd.con

Save the Date for the 21st Anniversary

Tee Up for a Cure

ÂŽ

Golf Outing and Dining Monday, August 12, 2019

12:30 p.m. Shotgun start Ozaukee Country Club 10823 North River Road, Mequon, Wisconsin 53092 Cocktails and Silent Auction at 5:00 P.M. Dining and Live Auction to Follow $400/golfer Includes use of practice facility, lunch, 18 holes and dining.

$125/Dining only For more information or to reserve your spot, please contact Kim Jones Call ~ 414-640-7525 or Email ~ KimAJones3@gmail.com Kadie Jelenchick Call ~ 414-324-1868 or Email ~ KJelenchick@foley.com

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2019 SHOWHOUSE for a Cure

Ken Michaels Furniture A proud sponsor of the WISCONSIN BREAST CANCER

SHOWHOUSE FURNITURE ~ INTERIOR DESIGN ~ MATTRESSES brookfield

18525 West Capitol

n

262-781-3850

greenfield

4140 South 108th Street 414-529-4282 n

clearance center

423 North 3rd Street 414-271-7335 n

www.kenmichaelsfurniture.com