Appendix 23 Assessing outbreak-specific control strategies against FMD – a simulation approach

perspectives in the generalization of the use of this high throughput technology of microarrays to the study of FMDV epidemiology.

Integrated quality controlled strategy

All above mentioned diagnostics are often evaluated as a pure laboratory stand alone method. Seldom FMDV detection is seen as a complex of different elements in which each step is important. The weakest element in the chain determines the strength of the chain. Whether new diagnostic methods brings in an added value or not depends on what exactly we want to achieve and if that new method fill in the gap. One of the main gaps is full validation of tests with determining the test performance and an accompanying continuous QA/QC system. Although very important for reliability and sampling strategies it is rarely studied. The majority of institutes performing FMDV diagnosis are research institutes. Research money is not available for validation activities and the research boards of these institutes do not consider these activities as high level research. Researcher themselves find it often boring and certainly not innovating. It demands a lot of work before it can be published and is often not accepted by high qualified scientific journals. Money must be made available for validation studies.

FMD diagnosis should be seen as a complete system (contingency plan) that has to be managed very well. First the strategy has to be defined with the goals on short and long terms, with the weaknesses and the strong elements. It should be clearly defined where investments are needed to obtain the goals and which elements can be left out. Some new developments are nice to have but are not essential to the strategy. Once the strategy is clearly defined it should be applied but must be continuously checked. A quality control of the strategy must be implemented. When elements are out of line actions must be taken and if necessary the strategy adapted.

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