STATEMENT ON TR'DJ DISCUSSION OF FOOT AND MOUTH DISEASE AT THE TENTH SESSION OF THE FAO CONFERENCE

5) It was strow;ly recommencled that no European institute should prepare vaccine from exotic types of the virus without the express approval of this meeting.

6) While it was desirable that laboratory research on attenuated,living virus-vaccines should for the present, such continue 9 vaccines it vms expressly recommen should not be used in the ded that, field in Europe.

7) There should be further meetings and discussions between the two Commissions so that the necessary contj_nui t;y of joint action might be assured.

The Session accepted and agreed with both reports.

The Presiclent of OIE welcomed this further collaboration between the two organizations. He s tressed that the Commission was regional in its work while OIE had a world-wide interest in all epizootic diseases including footand-mouth disease. He also felt that the PirbriGht Institute should continue to develop its activities and that everything possible should be clone to encourage of virus: countries to and that OIE send samples to the Institute for identifying types should recognize the Pirbright Institute as the World Foot-and-Mouth Disease Reference Laboratory.

Since there were queries about the status of the four exotic types, Dr. Galloway prepared the following note on these exotic types of virus of foot-and-mouth disease and new variants of the :Guropean types�-

The Research Institute at Pirbright established the identity of the types SAT 1 9 SAT II, SAT III and Asia I not only by differential serological (complement fixation and serum neutralisation) tests but also by cross-immunity tests in guinea-pigs and in cattle. They are definitely immunological distinct types of the virus. C attle recovered from infection with a strain of virus of any of the seven known types r0main fully susceptible to infection with a strain of virus of any of the other six types.

On the other hand, strains of virus referrecl to as sub-types (11variants11) can be differentiated by serological tests but not by cross immunity tests in cattle or guinea-pigs. As the more appropriate t0rm 9 sub-type 9 signifies, such strains of virus are classifiable in one 01° at.her of the seven immunological types. It is clear 7 however, since in appropriate quantitative cross vaccination tests in cattle, sub-types can be differentiated, as they can serologically, that their .existence has to be taken into account in preparing highly effective vaccines. STATEMENT ON THE ])ISCUSSION OF FOOT-AND-EfOUTH DISEASE AT THE TENTH SESSION OJ:l7 THE FAO CONFERENCE Resolution N.o. 21 /59. on Foot-and-Mouth Disease Control The following resolution was adopted by the FAO Conference in 1959g-