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VOLUME 1

Introduction and General Neurosurgery

William T. Couldwell, M. Sean Grady, Karl Schaller, Allan R. Tunkel, Benjamin I. Rapoport, Or Cohen-Inbar, Perry A. Ball, Basant K. Misra, Ugur Türe, Dennis G. Vollmer, and Martin H. Weiss

Basic and Clinical Sciences

Michel Kliot, Robert M. Friedlander, Michael M. Haglund, Philip J. Horner, and Michael G. Kaplitt

Epilepsy

Nitin Tandon, Guy M. McKhann, Jorge Á. Gonzalez-Martinez, Samden Lhatoo, and Andrew W. McEvoy

Functional Neurosurgery

Ron L. Alterman, Andres M. Lozano, Joachim K. Krauss, Takaomi Taira, and Ludvic Zrinzo

VOLUME 2

Oncology

E. Antonio Chiocca, Manmeet S. Ahluwalia, Tracy Batchelor, Francesco DiMeco, Linda M. Liau, Russell R. Lonser, Michael W. McDermott, Zvi Ram, Henry Brem, and Raymond Sawaya

Pain

Kim J. Burchiel, Turo J. Nurmikko, and Marc Sindou

Pediatrics

Andrew Jea, Gerald A. Grant, Nathan R. Selden, Anthony Avellino, James Tait Goodrich, Richard David Hayward, Mark D. Krieger, James T. Rutka, and Shenandoah Robinson

VOLUME 3

Peripheral Nerve Disorders

Aaron G. Filler, Allan J. Belzberg, Liang Chen, Holly S. Gilmer, Mark A. Mahan, and Martijn J.A. Malessy

Radiation

Jason Sheehan, Steven D. Chang, and Peter C. Gerszten

Spine

Christopher I. Shaffrey, Justin S. Smith, Christopher P. Ames, Dean Chou, Andrew T. Dailey, Michael G. Fehlings, Zoher Ghogawala, Ziya L. Gokaslan, James S. Harrop, Manish K. Kasliwal, Praveen V. Mummaneni, Jon Park, Daniel K. Resnick, Amer F. Samdani, Paul Santiago, Juan S. Uribe, and Michael Y. Wang

VOLUME 4

Trauma

Geoffrey T. Manley, Peter J. Hutchinson, Gregory W.J. Hawryluk, Andrew I.R. Maas, Laura Benjamin Ngwenya, Guy Rosenthal, and Anthony Strong

Microsurgical and Interventional Treatment of Vascular Diseases

E. Sander Connolly, Jr., William J. Mack, Gavin W. Britz, Aaron S. Dumont, Chirag D. Gandhi, Steven L. Giannotta, Roberto C. Heros, Kazuhiro Hongo, Michael T. Lawton, Peter D. Le Roux, Fredric B. Meyer, Marcus Stoodley, and Gregory J. Zipfel

Youmans & Winn Neurological Surgery

EIGHTH EDITION

Professor of Neurosurgery

University of Iowa Carver College of Medicine Iowa City, Iowa; Professor of Neurosurgery and Neuroscience

Icahn School of Medicine at Mount Sinai New York, New York; Visiting Professor of Surgery (Neurosurgery)

Tribhuvan University Teaching Hospital Kathmandu, Nepal

Elsevier

1600 John F. Kennedy Blvd. Ste 1800 Philadelphia, PA 19103-2899

YOUMANS & WINN NEUROLOGICAL SURGERY, EIGHTH EDITION

Copyright © 2023 by Elsevier, Inc. All rights reserved.

ISBN: 978-0-323-66192-8

No part of this publication may be reproduced or transmitted in any form or by any means, electronic or mechanical, including photocopying, recording, or any information storage and retrieval system, without permission in writing from the publisher. Details on how to seek permission, further information about the Publisher’s permissions policies and our arrangements with organizations such as the Copyright Clearance Center and the Copyright Licensing Agency, can be found at our website: www.elsevier.com/permissions

This book and the individual contributions contained in it are protected under copyright by the Publisher (other than as may be noted herein).

Notice

Practitioners and researchers must always rely on their own experience and knowledge in evaluating and using any information, methods, compounds or experiments described herein. Because of rapid advances in the medical sciences, in particular, independent verification of diagnoses and drug dosages should be made. To the fullest extent of the law, no responsibility is assumed by Elsevier, authors, editors or contributors for any injury and/or damage to persons or property as a matter of products liability, negligence or otherwise, or from any use or operation of any methods, products, instructions, or ideas contained in the material herein.

Previous editions copyrighted 2017, 2011, 2004, 1996, 1990, 1982, and 1973.

Content Strategists: Humayra R. Khan and Belinda Kuhn

Senior Content Development Specialist: Jennifer Shreiner

Publishing Services Manager: Catherine Jackson

Health Content Management Specialist: Kristine Feeherty

Design Direction: Margaret Reid

While serving at a Level One trauma center, Dr. Ko painted a brain a day for 1 year after Andy Warhol. Some of the brains contain autobiographical references. Kathryn Ko, MD, MFA, graduated from the University of Hawai’i School of Medicine & completed Neurosurgery training at Mt Sinai. She earned a Master of Fine Arts in 2012. Her practice & art studio are located in New York City. More of her art can be viewed on Instagram/TikTok @doc_ambidexter

Printed in Canada

Last digit is the print number: 9 8 7 6 5 4 3 2 1

Warholian Brains

Elsevier

1600 John F. Kennedy Blvd.

Ste 1800 Philadelphia, PA 19103-2899

YOUMANS & WINN NEUROLOGICAL SURGERY, EIGHTH EDITION

Copyright © 2023 by Elsevier, Inc. All rights reserved.

ISBN: 978-0-323-66192-8

No part of this publication may be reproduced or transmitted in any form or by any means, electronic or mechanical, including photocopying, recording, or any information storage and retrieval system, without permission in writing from the publisher. Details on how to seek permission, further information about the Publisher’s permissions policies and our arrangements with organizations such as the Copyright Clearance Center and the Copyright Licensing Agency, can be found at our website: www.elsevier.com/permissions

This book and the individual contributions contained in it are protected under copyright by the Publisher (other than as may be noted herein).

Practitioners and researchers must always rely on their own experience and knowledge in evaluating and using any information, methods, compounds or experiments described herein. Because of rapid advances in the medical sciences, in particular, independent verification of diagnoses and drug dosages should be made. To the fullest extent of the law, no responsibility is assumed by Elsevier, authors, editors or contributors for any injury and/or damage to persons or property as a matter of products liability, negligence or otherwise, or from any use or operation of any methods, products, instructions, or ideas contained in the material herein.

Previous editions copyrighted 2017, 2011, 2004, 1996, 1990, 1982, and 1973.

Content Strategists: Humayra R. Khan and Belinda Kuhn

Senior Content Development Specialist: Jennifer Shreiner

Publishing Services Manager: Catherine Jackson

Health Content Management Specialist: Kristine Feeherty

Design Direction: Margaret Reid

This acrylic painting refers to the procedure published in Neurosurgery, Ko & Segan, 2007; 60(4 Suppl 2):255–258. Kathryn Ko, MD, MFA, graduated from the University of Hawai’i School of Medicine & completed Neurosurgery training at Mt Sinai. She earned a Master of Fine Arts in 2012. Her practice & art studio are located in New York City. More of her art can be viewed on Instagram/TikTok @doc_ambidexter.

Hinge Craniectomy

Elsevier

1600 John F. Kennedy Blvd.

Ste 1800 Philadelphia, PA 19103-2899

YOUMANS & WINN NEUROLOGICAL SURGERY, EIGHTH EDITION

Copyright © 2023 by Elsevier, Inc. All rights reserved.

ISBN: 978-0-323-66192-8

No part of this publication may be reproduced or transmitted in any form or by any means, electronic or mechanical, including photocopying, recording, or any information storage and retrieval system, without permission in writing from the publisher. Details on how to seek permission, further information about the Publisher’s permissions policies and our arrangements with organizations such as the Copyright Clearance Center and the Copyright Licensing Agency, can be found at our website: www.elsevier.com/permissions.

This book and the individual contributions contained in it are protected under copyright by the Publisher (other than as may be noted herein).

Notice

Practitioners and researchers must always rely on their own experience and knowledge in evaluating and using any information, methods, compounds or experiments described herein. Because of rapid advances in the medical sciences, in particular, independent verification of diagnoses and drug dosages should be made. To the fullest extent of the law, no responsibility is assumed by Elsevier, authors, editors or contributors for any injury and/or damage to persons or property as a matter of products liability, negligence or otherwise, or from any use or operation of any methods, products, instructions, or ideas contained in the material herein.

Previous editions copyrighted 2017, 2011, 2004, 1996, 1990, 1982, and 1973.

Content Strategists: Humayra R. Khan and Belinda Kuhn

Senior Content Development Specialist: Jennifer Shreiner

Publishing Services Manager: Catherine Jackson

Health Content Management Specialist: Kristine Feeherty

Design Direction: Margaret Reid

Workshop Tools

3 acrylic paintings + charcoal drawing. Kathryn Ko, MD, MFA, graduated from the University of Hawai’i School of Medicine & completed Neurosurgery training at Mt Sinai. She earned a Master of Fine Arts in 2012. Her practice & art studio are located in New York City. More of her art can be viewed on Instagram/TikTok @doc_ambidexter.

Elsevier

1600 John F. Kennedy Blvd.

Ste 1800 Philadelphia, PA 19103-2899

YOUMANS & WINN NEUROLOGICAL SURGERY, EIGHTH EDITION

Copyright © 2023 by Elsevier, Inc. All rights reserved.

ISBN: 978-0-323-66192-8

No part of this publication may be reproduced or transmitted in any form or by any means, electronic or mechanical, including photocopying, recording, or any information storage and retrieval system, without permission in writing from the publisher. Details on how to seek permission, further information about the Publisher’s permissions policies and our arrangements with organizations such as the Copyright Clearance Center and the Copyright Licensing Agency, can be found at our website: www.elsevier.com/permissions

This book and the individual contributions contained in it are protected under copyright by the Publisher (other than as may be noted herein).

Notice

Practitioners and researchers must always rely on their own experience and knowledge in evaluating and using any information, methods, compounds or experiments described herein. Because of rapid advances in the medical sciences, in particular, independent verification of diagnoses and drug dosages should be made. To the fullest extent of the law, no responsibility is assumed by Elsevier, authors, editors or contributors for any injury and/or damage to persons or property as a matter of products liability, negligence or otherwise, or from any use or operation of any methods, products, instructions, or ideas contained in the material herein.

Previous editions copyrighted 2017, 2011, 2004, 1996, 1990, 1982, and 1973.

Content Strategists: Humayra R. Khan and Belinda Kuhn

Senior Content Development Specialist: Jennifer Shreiner

Publishing Services Manager: Catherine Jackson

Health Content Management Specialist: Kristine Feeherty

Design Direction: Margaret Reid

Acrylic painting of Dr. Ko doing spinal fusion surgery. Kathryn Ko, MD, MFA, graduated from the University of Hawai’i School of Medicine & completed Neurosurgery training at Mt Sinai. She earned a Master of Fine Arts in 2012. Her practice & art studio are located in New York City. More of her art can be viewed on Instagram/TikTok @doc_ambidexter Printed in Canada

Self Portrait ∼ What Women Do

DEDICATION

The 8th edition is dedicated to Julian Ray Youmans, who almost 50 years ago in 1973 had the foresight and wisdom to initiate and launch this textbook and the grit to remain editorin-chief of the 2nd (1982), 3rd (1990), and 4th (1996) editions.

Julian Youmans was born January 2, 1928, at home near Baxley, Georgia. After finishing high school, he served in the South Pacific as a corpsman in the US Navy from September 1944 to May 1946. After demobilization from the Navy in June 1946, he enrolled at Emory University. As was common in the immediate post-WWII era, he had an abbreviated undergraduate experience and entered Emory University School of Medicine 2 years later. He received a Bachelor of Science degree in 1949 and a Doctor of Medicine degree in 1952.

In 1952, he began an internship at the University of Michigan in Ann Arbor followed by 2 years of general surgery training. From 1955 to 1956, he was awarded the National Foundation Fellowship and spent a year as a registrar and clerk at the Institute of Neurology, Queens Square, London. From 1956 to 1958, he was a resident under Richard Schneider in the Department of Neurological Surgery at the University of Michigan. Simultaneously with the residency in General Surgery and Neurosurgery, he was enrolled in the Rackham School of Graduate Studies at the University of Michigan, from which he received a Master of Science degree in 1955 and a Doctor of Philosophy in Neuroanatomy and Neurophysiology in 1957.

Dr. Youmans practiced neurosurgery in St. Petersburg, Florida, for 1 year (1957–1958) and then moved to the University of Mississippi in Jackson as an assistant professor and subsequently was promoted to associate professor. While at the University of Mississippi, he worked with the Mississippi legislature and governor to pass the first law in the country requiring installation of seat belts in new automobiles. This legislation was followed by similar ones in many other states and eventually led to the installation of seat belts in all new cars sold in the United States. While most, if not all, neurosurgeons have saved many lives, Dr. Youmans’ public advocacy of seat belts undoubtedly saved millions of American lives, including his own following a car accident in 2017.a

In 1963 at age 36, he became professor and founding chairman of the Department of Neurological Surgery at the Medical University of South Carolina in Charleston and initiated a resident training program in 1964. After 4 years in Charleston, in 1967 he was invited to lead the newly forming Department of Neurosurgery at the University of California, Davis. Thus, for the second time, he founded a university-based department of neurosurgery as well as an American Board of Neurological Surgery (ABNS)–approved residency program. He remained as chair of the Department of Neurosurgery at University of California, Davis until 1982. Under his leadership, the department expanded significantly. Few, if any, neurosurgeons have had a similar experience of creating two new US university departments.

Dr. Youmans authored more than 160 articles on a wide range of subjects. His primary research interest was focused on cerebral blood flow and head injury. However, his name is primarily recognized for his creation and repetitive editorship of his iconic and comprehensive textbook, Neurological Surgery, which JAMA termed the “Bible of Neurosurgery.”b The 1st edition was 2,024 pages in three volumes. The 2nd, 3rd, and 4th editions expanded more than twofold in pages and topics.

I was honored when Dr. Youmans asked me to succeed him as editor-in-chief of the 5th edition in 1997. In turn, when I asked him what motivated him to initiate Neurological Surgery, he said modestly:

“I just thought it was a good idea.”

A half a century of Neurological Surgery’s continuous publication is proof that Julian Youmans’ idea was more than good; it was great. And as John F. Kennedy noted in 1963:

“A man may die, nations may rise and fall, but an idea lives on.”

5th, 6th, 7th, and 8th editions

Youmans & Winn Neurological Surgery

aWoodland Daily Democrat, June 23, 2017.

bJAMA. 2004;292(24):3032–3038.

Editor-in-Chief

H. Richard Winn, MD Professor of Neurosurgery

University of Iowa Carver College of Medicine

Iowa City, Iowa; Professor of Neurosurgery and Neuroscience

Icahn School of Medicine at Mount Sinai

New York, New York;

Visiting Professor of Surgery (Neurosurgery)

Tribhuvan University Teaching Hospital Kathmandu, Nepal

Section Editors

SECTION I. INTRODUCTION TO NEUROSURGERY AND SECTION II. GENERAL NEUROSURGERY

William T. Couldwell, MD, PhDa Professor and Chair Department of Neurosurgery University of Utah School of Medicine Salt Lake City, Utah

M. Sean Grady, MD a Professor of Neurosurgery Perelman School of Medicine at the University of Pennsylvania Philadelphia, Pennsylvania

Karl Schaller, MDa Professor and Chairman Department of Neurosurgery University Hospital of Geneva Geneva, Switzerland

Allan R. Tunkel, MD, PhDa Professor of Medicine and Medical Science Senior Associate Dean for Medical Education The Warren Alpert Medical School of Brown University Providence, Rhode Island

Benjamin I. Rapoport, MD, PhD Assistant Professor of Neurosurgery Director, Mount Sinai BioDesign Program Icahn School of Medicine Mount Sinai Medical System New York, New York

Or Cohen-Inbar, MD PhD

Assistant Professor of Neurological Surgery University of Pittsburgh School of Medicine Pittsburgh, Pennsylvania; Assistant Professor of Neurological Surgery University of Virginia School of Medicine Charlottesville, Virginia; Neurological Surgery UPMC Western Maryland Cumberland, Maryland

Perry A. Ball, MD Professor of Surgery and Anesthesiology Geisel School of Medicine at Dartmouth Dartmouth-Hitchcock Medical Center Lebanon, New Hampshire

Basant K. Misra, MBBS, MS, MCh, Diplomate National Board Head, Division of Neurosurgery and Gamma Knife Radiosurgery Head, Department of Surgery

PD Hinduja National Hospital and Medical Research Centre Head, Department of Neurosurgery Hinduja Hospital, Khar Mumbai, India

Ugur Türe, MD Professor and Chair Department of Neurosurgery Yeditepe University Istanbul, Turkey

aLead Section Editor.

Dennis G. Vollmer, MD Professor of Neurological Surgery University of Virginia School of Medicine Charlottesville, Virginia

Martin H. Weiss, MD Professor of Neurological Surgery

The Martin H. Weiss Chair in Neurological Surgery

Keck School of Medicine of the University of Southern California Los Angeles, California

SECTION III. BASIC AND CLINICAL SCIENCES

Michel Kliot, MD, MA a Clinical Professor of Neurological Surgery

Co-Director, Peripheral Nerve Center

Stanford University Medical Center

Palo Alto, California

Robert M. Friedlander, MD, MA Walter E. Dandy Professor and Chairman Department of Neurological Surgery University of Pittsburgh School of Medicine Pittsburgh, Pennsylvania

Michael M. Haglund, MD, PhD, MACM Distinguished Professor of Neurosurgery, Neurobiology, and Global Health

Duke University School of Medicine Durham, North Carolina

Philip J. Horner, PhD

Scientific Director, Center for Neuroregenerative Medicine

Co-Director, Center for Regenerative and Restorative Neurosurgery

Houston Methodist Research Institute Houston, Texas

Michael G. Kaplitt, MD, PhD Professor of Neurological Surgery Vice Chairman for Research

Director of Stereotactic and Functional Neurosurgery

Weill Cornell Medical College New York, New York

SECTION IV. EPILEPSY

Nitin Tandon, MD, FAANS a Professor and Vice Chairman Department of Neurosurgery University of Texas Health Science Center; Director, Epilepsy Surgery Memorial Hermann Hospital; Adjunct Professor of Electrical and Computer Engineering

Rice University Houston, Texas

Guy M. McKhann, MDa

Professor of Neurological Surgery

Columbia University College of Physicians & Surgeons; Director, Epilepsy and Movement Disorder Surgery Director, Adult Hydrocephalus Center; Director, Awake Brain Mapping for Tumors and Epilepsy

New York-Presbyterian Columbia University Medical Center

New York, New York

Jorge Á. Gonzalez-Martinez, MD, PhD, FAANS Epilepsy Center Department of Neurological Surgery Cleveland Clinic Cleveland, Ohio

Samden Lhatoo, MD, FRCP(Lon)

John P and Kathrine G McGovern Distinguished University Professor of Neurology

Executive Vice Chair of Neurology University of Texas Health Science Center of Houston Houston, Texas

Andrew W. McEvoy, MBBS, MD, FRCS(Lond), FRCS(SN)

Chair of Neurosciences Institute Cleveland Clinic London; Consultant Neurosurgeon

National Hospital for Neurology and Neurosurgery Institute of Neurology University College London; Honorary Consultant Neurosurgeon Great Ormond Street Hospital for Children London, United Kingdom

SECTION V. FUNCTIONAL NEUROSURGERY

Ron L. Alterman, MD, MBA a Professor of Neurosurgery Harvard Medical School; Chief, Division of Neurosurgery Beth Israel Deaconess Medical Center Boston, Massachusetts

Andres M. Lozano, MD, PhD a Professor and Chairman Division of Neurosurgery University of Toronto Faculty of Medicine Toronto, Ontario, Canada

Joachim K. Krauss, MD Professor of Neurosurgery Chairman and Director Department of Neurosurgery Medical School Hannover, Medizinische Hochschule Hannover Hannover, Germany

Takaomi Taira, MD, PhD Professor of Neurosurgery Tokyo Women’s Medical University Tokyo, Japan

Ludvic Zrinzo, MD, PhD, FRCSEd Professor of Neurosurgery

Functional Neurosurgery Unit Department of Clinical and Movement Neurosciences

aLead Section Editor.

University College London Institute of Neurology, Queen Square; Consultant Neurosurgeon

Victor Horsley Department of Neurosurgery

National Hospital for Neurology and Neurosurgery

London, United Kingdom

SECTION VI. ONCOLOGY

E. Antonio Chiocca, MD, PhD, FAANS a Harvey W. Cushing Professor of Neurosurgery

Harvard Medical School; Neurosurgeon-in-Chief and Chair Department of Neurosurgery

Co-Director, Institute for the Neurosciences

Brigham and Women’s Hospital Boston, Massachusetts

Manmeet S. Ahluwalia, MD Professor of Medicine

Case Western Reserve University School of Medicine;

Head of Operations

Brain Tumor and Neuro-Oncology Center Cleveland Clinic Cleveland, Ohio

Tracy T. Batchelor, MD

Miriam Sydney Joseph Professor of Neurology

Harvard Medical School

Chair, Department of Neurology

Brigham and Women’s Hospital Boston, Massachusetts

Francesco DiMeco, MD Director, Department of Neurosurgery

Istituto Nazionale Neurologico “C.Besta” Full Professor of Neurosurgery Department of Pathophysiology and Transplantation University of Milan Milan, Italy;

Assistant Professor (adjunct) Department of Neurological Surgery

Johns Hopkins Medical School Baltimore, Maryland

Linda M. Liau, MD, PhD, MBA Professor and Chair Department of Neurosurgery

University of California Los Angeles

David Geffen School of Medicine at UCLA

Los Angeles, California

Russell R. Lonser, MD Professor and Chairman Department of Neurological Surgery

The Ohio State University Wexner Medical Center Columbus, Ohio

Michael W. McDermott, MD Professor of Neurosurgery

Chair, Division of Neuroscience

Herbert Wertheim College of Medicine at Florida International University; Chief Physician Executive

Miami Neuroscience Institute Miami, Florida

Zvi Ram, MD

Chairman Department of Neurosurgery

Tel Aviv Medical Center

Tel Aviv, Israel

Henry Brem, MD b Harvey Cushing Professor and Director Department of Neurosurgery

Professor of Neurosurgery, Ophthalmology, Oncology, and Biomedical Engineering

Johns Hopkins University School of Medicine; Neurosurgeon-in-Chief Johns Hopkins Medical Institutions Director, Hunterian Neurosurgical Research Center Baltimore, Maryland

Raymond Sawaya, MD b Professor and Founding Chair Department of Neurosurgery

The University of Texas MD Anderson Cancer Center Houston, Texas

SECTION VII. PAIN

Kim J. Burchiel, MD, FACS a John Raaf Professor of Neurological Surgery

Professor of Anesthesiology and Perioperative Medicine

Oregon Health & Science University Portland, Oregon

Turo J. Nurmikko, MD, PhD Professor in Pain Relief Neuroscience Research Centre

The Walton Centre NHS Foundation Trust Meols, Wirral, United Kingdom

Marc Sindou, MD, DSc

Professor Emeritus of Neurosurgery University of Lyon Lyon, France

SECTION VIII. PEDIATRICS

Andrew Jea, MD, MHA, FACS, FAAPa Professor and Vice-Chair Department of Neurosurgery

The University of Oklahoma College of Medicine; Chief of Pediatric Neurosurgery

Surgical Director of Quality and Patient Safety

Co-Director of Pediatric Neurosciences Oklahoma Children’s Hospital Oklahoma City, Oklahoma

Gerald A. Grant, MD, FACS a Professor of Neurosurgery

Arline and Pete Harman Endowed Faculty Scholar

Division Chief, Pediatric Neurosurgery Stanford University School of Medicine

Stanford, California

Nathan R. Selden, MD, PhD, FACS, FAAP Campagna Professor and Chair

Department of Neurological Surgery

Oregon Health & Science University Portland, Oregon

aLead Section Editor.

bSenior Section Editor.

Anthony M. Avellino, MD, MBA

Assistant Vice President for Health Sciences

Chief Clinical and Medical Officer

Michigan State University East Lansing, Michigan

James Tait Goodrich, MD, PhD, DSci (Hon)† Professor of Clinical Neurosurgery, Pediatrics, Plastic and Reconstructive Surgery

Albert Einstein College of Medicine

Leo Davidoff Department of Neurosurgery

Director, Division of Pediatric Neurosurgery

Children’s Hospital at Montefiore Montefiore Medical Center Bronx, New York

Richard D. Hayward, MBBS, FRCS (Eng) Professor of Paediatric Neurosurgery

Great Ormond Street Hospital for Children London, United Kingdom

Mark D. Krieger, MD

Professor of Clinical Neurological Surgery

Keck School of Medicine of the University of Southern California

Senior Vice President and Surgeon-in-Chief Department of Surgery

Director, Neurological Institute

Billy and Audrey L. Wilder Endowed Chair in Neurosurgery Chair

Children’s Hospital Los Angeles Los Angeles, California

James T. Rutka, MD, PhD

Professor and R.S. McLaughlin Chair Department of Surgery University of Toronto Faculty of Medicine; Director of the Arthur and Sonia Labatt Brain Tumour Research Centre

Division of Paediatric Neurosurgery

The Hospital for Sick Children Toronto, Ontario, Canada

Shenandoah Robinson, MD, FAAP, FACS Professor of Neurosurgery

Division of Pediatric Neurosurgery

Johns Hopkins University School of Medicine Baltimore, Maryland

SECTION IX. PERIPHERAL NERVE DISORDERS

Aaron G. Filler, MD, PhD, JD, FRCS a Medical Director Institute for Nerve Medicine

Santa Monica, California; Staff Neurosurgeon

Cedars Sinai Medical Center

Los Angeles, California

Allan J. Belzberg, MD, FRCSC Professor of Neurosurgery and Plastic & Reconstructive Surgery

The George J. Heuer Professor Director, Peripheral Nerve Surgery

Co-Director, Neurosurgery Pain Research Institute

Johns Hopkins Medical Institutions Baltimore, Maryland

†Deceased March 30, 2019.

Liang Chen, MD, PhD

Professor

Hand Surgery Department Huashan Hospital of Fudan University Shanghai, China

Holly S. Gilmer, MD

Attending Neurosurgeon Michigan Head & Spine Institute Southfield, Michigan

Mark A. Mahan, MD

Associate Professor of Neurosurgery University of Utah School of Medicine Salt Lake City, Utah

Martijn J.A. Malessy, MD, PhD Professor of Nerve Surgery Department of Neurosurgery Leiden University Medical Center Leiden, The Netherlands

SECTION X. RADIATION

Jason P. Sheehan, MD a Professor of Neurosurgery University of Virginia School of Medicine Charlottesville, Virginia

Steven D. Chang, MD

Robert C. and Jeannette Powell Professor Department of Neurosurgery Stanford School of Medicine Stanford, California

Peter C. Gerszten, MD, MPH, FACS

Peter E. Sheptak Professor Departments of Neurological Surgery and Radiation Oncology University of Pittsburgh Medical Center Pittsburgh, Pennsylvania

SECTION XI. SPINE

Christopher I. Shaffrey, MDa Professor of Orthopaedic Surgery Chief, Spine Division Duke University Medical Center Durham, North Carolina

Justin S. Smith, MD, PhDa Professor of Neurosurgery University of Virginia Health System Co-Director, UVA Spine Center Charlottesville, Virginia

Christopher P. Ames, MD

Professor of Neurological Surgery and Orthopedic Surgery University of California, San Francisco, School of Medicine San Francisco, California

Dean Chou, MD

Professor of Neurosurgery

University of California, San Francisco School of Medicine San Francisco, California

Andrew T. Dailey, MD Professor of Neurosurgery

University of Utah School of Medicine

Salt Lake City, Utah

aLead Section Editor.

Michael G. Fehlings, MD, PhD, FRCSC, FACS

Professor of Neurosurgery

Vice Chair, Research

Department of Surgery

Co-Director, Spine Program

University of Toronto; Gerald and Tootsie Halbert Chair in Neural Repair and Regeneration

McLaughlin Scholar in Molecular Medicine

Toronto Western Hospital

University Health Network Toronto, Ontario, Canada

Zoher Ghogawala, MD, FACS Professor of Neurosurgery

Tufts University School of Medicine

Boston, Massachusetts; Chairman, Department of Neurosurgery

Lahey Hospital and Medical Center Burlington, Massachusetts

Ziya L. Gokaslan, MD, FAANS, FACS

Gus Stoll, MD Professor and Chair Department of Neurosurgery

The Warren Alpert Medical School of Brown University; Neurosurgeon-in-Chief

Rhode Island Hospital and The Miriam Hospital

Clinical Director, Norman Prince Neurosciences Institute

President, Brown Neurosurgery Foundation Providence, Rhode Island

James S. Harrop, MD

Professor of Neurological Surgery and Orthopedics

Sidney Kimmel Medical College at Thomas Jefferson University; Section Chief Division of Spine and Peripheral Nerve Disorders

Thomas Jefferson University Hospital Philadelphia, Pennsylvania

Manish K. Kasliwal, MD. MCh, FAANS

Assistant Professor Department of Neurological Surgery

Case Western Reserve University School of Medicine; Director, Minimally Invasive Spine Surgery Department of Neurological Surgery

University Hospitals Case Medical Center Cleveland, Ohio

Praveen V. Mummaneni, MD

Joan O’Reilly Endowed Professor

Vice Chair

UCSF Neurosurgery

Co-Director, UCSF Spine Center

University of California, San Francisco School of Medicine

San Francisco, California

Jon Park, MD, FRCSC Professor of Neurosurgery

Stanford University School of Medicine Stanford, California

Daniel K. Resnick, MD, MS

Professor and Vice Chairman Department of Neurosurgery

University of Wisconsin School of Medicine and Public Health Madison, Wisconsin

Amer F. Samdani, MD

Chief of Surgery

Department of Neurosurgery

Shriners Hospitals for Children-Philadelphia Philadelphia, Pennsylvania

Paul Santiago, MD

Professor of Neurological Surgery and Orthopedic Surgery

Washington University School of Medicine in St Louis St Louis, Missouri

Juan S. Uribe, MD

Professor and Vice Chair of Neurological Surgery

Chief, Division of Spinal Disorders

Volker K. H. Sonntag Chair of Spine Research Barrow Neurological Institute Phoenix, Arizona

Michael Y. Wang, MD, FAANS, FACS

Professor of Neurological Surgery and Rehabilitation Medicine

University of Miami Miller School of Medicine

Chief of Neurosurgery, University of Miami Hospital Director, Neurosurgical Spine Fellowship Miami, Florida

SECTION XII. TRAUMA

Geoffrey T. Manley, MD, PhD a

Professor in Residence and Vice Chairman Department of Neurological Surgery

Co-Director and Principal Investigator, Brain and Spinal Injury Center (BASIC)

University of California San Francisco; Chief of Neurosurgery

San Francisco General Hospital San Francisco, California

Peter J. Hutchinson, MBBS, PhD, FRCS (Surg Neurol)a

Professor of Neurosurgery and NIHR Research Professor

Department of Clinical Neurosciences

University of Cambridge Addenbrooke’s Hospital Cambridge, United Kingdom

Gregory W.J. Hawryluk, MD, PhD, FRCSC

Assistant Professor of Neurosurgery Department of Surgery

University of Manitoba Faculty of Medicine Winnipeg, Manitoba, Canada

Andrew I.R. Maas, MD, PhDa Emeritus Professor of Neurosurgery University of Antwerp Faculty of Medicine and Health Sciences University Hospital Antwerp Edegem, Belgium

Laura Benjamin Ngwenya, MD, PhD

Associate Professor of Neurosurgery, Neurology and Rehabilitation Medicine

University of Cincinnati College of Medicine Director, Neurotrauma Center University of Cincinnati Gardner Neurosciences Institute Cincinnati, Ohio

Guy Rosenthal, MD Director of Neurotrauma and Neurocritical Care Department of Neurosurgery Hadassah-Hebrew University Medical Center Jerusalem, Israel

aLead Section Editor.

Anthony Strong, DM, FRCSEd Emeritus Professor Department of Basic and Clinical Neuroscience King’s College London London, United Kingdom

SECTION XIII. MICROSURGICAL AND INTERVENTIONAL TREATMENT OF VASCULAR DISEASES

E. Sander Connolly, Jr., MD, FACS a Byron Stookey Professor of Neurological Surgery Chair, Department of Neurosurgery Columbia University Vagelos College of Physicians & Surgeons Director, Cerebrovascular Research Laboratory Surgical Director, Neuro-Intensive Care Unit New York-Presbyterian Columbia University Medical Center New York, New York

William J. Mack, MDa Professor of Neurological Surgery Vice Chair, Academic Affairs Director, Neurointerventional Program University of Southern California Keck School of Medicine Los Angeles, California

Gavin W. Britz, MD, MPH, MBA Chair of Neurosurgery Houston Methodist Hospital Houston, Texas

Aaron S. Dumont, MD

Charles B. Wilson Professor and Chair Department of Neurological Surgery Tulane University School of Medicine New Orleans, Louisiana

Chirag D. Gandhi, MD, FACS, FAANS Professor and Chairman Department of Neurosurgery Westchester Medical Center New York Medical College Valhalla, New York

Steven L. Giannotta, MD Professor and Chair Department of Neurological Surgery Keck School of Medicine of the University of Southern California Los Angeles, California

Roberto C. Heros, MD Professor of Neurosurgery University of Miami Miller School of Medicine Miami, Florida

Kazuhiro Hongo, MD, PhD Director, Department of Neurosurgery Ina Central Hospital Ina, Japan; Professor Emeritus Department of Neurosurgery Shinshu University School of Medicine Matsumoto, Japan

Michael T. Lawton, MD Professor and Chairman Department of Neurological Surgery

Barrow Neurological Institute Phoenix, Arizona

Peter D. Le Roux, MD, FACS, FNCS

Chief, Division of Neurosurgery

Bassett Healthcare

Cooperstown, New York; Professor of Neurosurgery

University of Rochester School of Medicine and Dentistry

Rochester, New York

Fredric B. Meyer, MD

Uihlein Professor and Enterprise Chair

Department of Neurologic Surgery

Executive Dean of Education

Mayo Clinic

Dean, Mayo Clinic Alix School of Medicine

Dean, Mayo Clinic College of Medicine and Science

Rochester, Minnesota

Marcus Stoodley, MD, PhD, FRACS Professor of Neurosurgery

Macquarie University Faculty of Medicine, Health and Human Sciences

Head, Neurosciences Program

Macquarie University Hospital Sydney, Australia

Gregory J. Zipfel, MD Professor of Neurosurgery

Washington University School of Medicine in St. Louis St. Louis, Missouri

Contributors

Bizhan Aarabi, MD, FRCSC

Professor of Neurosurgery

Director, Neurotrauma

University of Maryland School of Medicine

Baltimore, Maryland

393: Surgical Management and Prognosis of Penetrating Brain Injury

Rick Abbott, MD

Professor of Neurological Surgery

Albert Einstein College of Medicine Montefiore Medical Center

Bronx, New York

263: Tumors of the Spine, Spinal Canal, and Spinal Cord in Children

Muhammad M. Abd-El-Barr, MD, PhD

Assistant Professor of Neurosurgery

Duke University Medical Center

Durham, North Carolina

311: Differential Diagnosis of Spinal Disease

Taylor J. Abel, MD

Assistant Professor of Neurological Surgery

University of Pittsburgh School of Medicine

Surgical Director, Epilepsy Surgery Program

UPMC Children’s Hospital of Pittsburgh

Pittsburgh, Pennsylvania

93: Investigation of Human Cognition in Epilepsy Surgery Patients

Hussam Abou-Al-Shaar, MD

Resident Physician

Department of Neurological Surgery

University of Pittsburgh Medical Center

Pittsburgh, Pennsylvania

288: Peripheral Nerve Surgery for Central Nervous System Disorders

Feridun Acar, MD

Professor and Chair

Department of Neurosurgery

Odak Hospital

Denizli, Turkey

206: Dorsal Rhizotomy and Dorsal Root Ganglionectomy

Rebecca L. Achey, MD

Resident Physician

Department of Neurosurgery

Cleveland Clinic Lerner College of Medicine

The Cleveland Clinic Foundation

Cleveland, Ohio

77: Electrophysiologic Properties of the Mammalian Central Nervous System

Laurie L. Ackerman, MD, MA

Associate Professor of Neurological Surgery

Indiana University School of Medicine

Section of Pediatric Neurosurgery

Riley Hospital for Children

Indianapolis, Indiana

220: Syndromic Craniosynostosis

Nithin D. Adappa, MD

Associate Professor of Otorhinolaryngology

Department of OtorhinolaryngologyHead and Neck Surgery

The Hospital of the University of Pennsylvania Philadelphia, Pennsylvania

400: Traumatic Cerebrospinal Fluid Fistulas

P. David Adelson, MD, FACS, FAAP Director, Barrow Neurological Institute at Phoenix Children’s Hospital

Diane and Bruce Halle Chair of Pediatric Neurosciences

Chief, Pediatric Neurosurgery

Phoenix Children’s Hospital Professor of Child Health

University of Arizona College of Medicine

Phoenix, Arizona; Professor of Neurosurgery

Mayo Clinic

Scottsdale, Arizona

250: Management of Head Injury: Special Considerations in Children

Nitin Agarwal, MD

Chief Resident

Department of Neurological Surgery

University of Pittsburgh Medical Center

Pittsburgh, Pennsylvania

365: Sacropelvic Fixation: Anterior and Posterior Options

David H. Aguirre-Padilla, MD

Assistant Professor of Neurosurgery

Department of Neurosurgery & Neurology

University of Chile Faculty of Medicine;

Functional & Stereotactic Neurosurgeon

Hospital Clínico San Borja Arriarán; Director, Functional Neurosurgery Program

Clínica Las Condes

Santiago de Chile, Chile

114: Complication Avoidance in Deep Brain Stimulation Surgery

Manmeet S. Ahluwalia, MD

Professor of Medicine

Case Western Reserve University School of Medicine; Head of Operations

Brain Tumor and Neuro-Oncology

Center

Cleveland Clinic

Cleveland, Ohio

Overview and Controversies (Oncology)

295: Combining Ionizing Radiation and Systemic Therapies for Treatment of Brain Metastases

Shahjehan Ahmad, MD, MPH

Resident Physician

Department of Neurological Surgery

Rush University Medical Center

Chicago, Illinois

370: Minimally Invasive Transforaminal Lumbar Interbody Fusion and Posterior Approaches to Spine

A. Karim Ahmed, MD

Resident Physician Department of Neurosurgery

The Johns Hopkins University School of Medicine

Baltimore, Maryland

338: Classification and Treatment of O–C1 Craniocervical Injuries

358: Anterior Cervical Instrumentation

Raheel Ahmed, MD, PhD

Assistant Professor of Neurological Surgery

University of Wisconsin School of Medicine and Public Health

Madison, Wisconsin

260: Developmental Anomalies of the Craniovertebral Junction and Surgical Management

Imoigele P. Aisiku, MD, MSCR, MBA, FCCP

Associate Professor of Emergency Medicine

Harvard Medical School

Brigham and Women’s Hospital

Boston, Massachusetts

387: Critical Care Management of Traumatic Brain Injury

Muhammad A. Akbar, MD

Resident Physician, Division of Neurosurgery

PhD Candidate, Institute of Medical Science

University of Toronto

Toronto, Ontario, Canada

321: Evaluation and Treatment of Degenerative Cervical Myelopathy

Harith Akram, MBChB, PhD, FRCS (Neuro.Surg)

Consultant Neurosurgeon

Unit of Functional Neurosurgery University College London

The National Hospital for Neurology and Neurosurgery (UCLH)

Queen Square Institute of Neurology (UCL)

London, United Kingdom

108: Neuroimaging in Stereotactic Functional Neurosurgery

Ali Alaraj, MD

Associate Professor of Neurosurgery University of Illinois at Chicago Chicago, Illinois

411: Neurovascular Imaging

418: Extracranial Vertebral Artery Diseases

Jennifer S. Albrecht, PhD

Associate Professor of Epidemiology & Public Health

University of Maryland School of Medicine

Baltimore, Maryland

40: Traumatic Brain Injury in the Geriatric Patient

Felipe C. Albuquerque, MD

Professor of Neurosurgery

Assistant Director, Endovascular Surgery

Barrow Neurological Institute St. Joseph’s Hospital and Medical Center Phoenix, Arizona

431: Endovascular Approaches to Narrow-necked Intracranial Aneurysms

Michael J. Alexander, MD

Professor and Vice-Chairman Department of Neurosurgery

Cedars-Sinai Medical Center

Los Angeles, California

417: Nonatherosclerotic Carotid Lesions

Andrei V. Alexandrov, MD

Semmes Murphey Professor and Chair Department of Neurology University of Tennessee Health Sciences Center

Memphis, Tennessee

410: Diagnostic and Therapeutic Neurosonology

Andreas V. Alexopoulos, MD, MPH

Clinical Assistant Professor of Medicine

Cleveland Clinic Lerner College of Medicine at Case Western Reserve University

Program Director, Epilepsy Fellowship Neurological Institute Cleveland Clinic Foundation Cleveland, Ohio

82: Electroencephalography in Outpatient, Epilepsy Monitoring Unit, and Intensive Care Unit Settings

Zarina S. Ali, MD, MS

Assistant Professor of Neurosurgery

Perelman School of Medicine at the University of Pennsylvania

Philadelphia, Pennsylvania

276: Distal Entrapment Syndromes: Carpal Tunnel, Cubital Tunnel, Peroneal, and Tarsal Tunnel

400: Traumatic Cerebrospinal Fluid Fistulas

Kenan Al-Khalili, MD

Resident Physician

Department of Neurosurgery

University of Arizona School of Medicine

Tucson, Arizona

182: Neoplasms of the Paranasal Sinuses

Ossama Al-Mefty, MD

Lecturer in Neurosurgery

Harvard Medical School

Director, Skull Base Program Department of Neurosurgery

Brigham and Women’s Hospital Boston, Massachusetts

172: Meningiomas

Rami O. Al-Mefty, MD

Assistant Professor Department of Neurosurgery

Temple University

Lewis Katz School of Medicine

Philadelphia, Pennsylvania

172: Meningiomas

Iyad Alnahhas, MD, MSc

Assistant Professor of Neurological Surgery

Division of Neuro-oncology

Thomas Jefferson University Philadelphia, Pennsylvania

143: Clinical Features: Neurology of Brain Tumor and Paraneoplastic Disorders

Malek Alrobaian, MD

Consultant in Ophthalmology

King Abdulaziz Medical City for National Guard

Riyadh, Saudi Arabia; Fellow in Neuro-Ophthalmology

Wilmer Eye Institute

Johns Hopkins Hospital

Baltimore, Maryland

189: Pseudotumor Cerebri

Fadi Al-Saiegh, MD

Resident Physician

Department of Neurological Surgery

The Sidney Kimmel Medical College at Thomas Jefferson University

Philadelphia, Pennsylvania

36: The Neurosurgical Intensive Care Unit and the Unique Role of the Neurosurgeon

Ron L. Alterman, MD, MBA

Professor of Neurosurgery

Harvard Medical School; Chief, Division of Neurosurgery

Beth Israel Deaconess Medical Center

Boston, Massachusetts

Overview and Controversies (Functional Neurosurgery)

112: Deep Brain Stimulation for Dystonia

114: Complication Avoidance in Deep Brain Stimulation Surgery

David B. Altshuler, MD, MS

Chief Resident Department of Neurosurgery

University of Michigan Medical School

Ann Arbor, Michigan

163: Central Nervous System Embryonal Tumors

Peter S. Amenta, MD

Associate Professor of Neurological Surgery

Tulane University School of Medicine

New Orleans, Louisiana

464: Microsurgical Treatment of Spinal Vascular Malformations

Christopher P. Ames, MD

Professor of Neurological Surgery and Orthopedic Surgery

University of California, San Francisco, School of Medicine

San Francisco, California

Overview and Controversies (Spine)

314: Predictive Analytics in the Treatment of Spinal Disorders

351: Evaluation and Treatment of Adult Scoliosis and Sagittal Plane Deformity

352: Evaluation and Treatment of Proximal Junctional Kyphosis

Sepideh Amin-Hanjani, MD

Professor of Neurosurgery

Co-Director, Neurovascular Surgery

University of Illinois College of Medicine at Chicago Chicago, Illinois

418: Extracranial Vertebral Artery Diseases

Mario Ammirati, MD, MBA

Professor Center for Biotechnology Department of Biology

College of Science and Technology; Director of Innovative

Neurotherapeutic Research Program

Sbarro Health Research Organization

Temple University

Philadelphia, Pennsylvania

Philadelphia, Pennsylvania

179: Overview of Skull Base Tumors

Norberto Andaluz, MD, MBA, FACS

Professor of Neurosurgery and Otolaryngology, Head and Neck

Surgery

Director, Division of Skull Base Surgery

University of Cincinnati College of Medicine

Cincinnati, Ohio

449: Endovascular Management of Cerebral Vasospasm

Richard C.E. Anderson, MD, FACS, FAAP

Associate Professor of Neurological Surgery

Columbia University Medical Center

New York, New York

262: Surgical Management of the Pediatric Subaxial Cervical Spine

Pablo Andrade, MD, PhD

Consultant Neurosurgeon

Department of Stereotactic and Functional Neurosurgery

University Hospital of Cologne Cologne, Germany

121: Surgery for Tourette Syndrome

William J. Ares, MD

Resident Physician

Department of Neurological Surgery

University of Pittsburgh Medical Center

Pittsburgh, Pennsylvania

406: Acute Surgical and Endovascular Management of Ischemic and Hemorrhagic Stroke

Jeffrey E. Arle, MD, PhD, FAANS

Associate Professor of Neurosurgery

Harvard Medical School

Associate Chief, Division of Neurosurgery

Beth Israel Deaconess Medical Center

Boston, Massachusetts

115: Neurophysiologic Monitoring for Movement Disorder Surgery

129: Motor Cortex Stimulation for Pain and Movement Disorders

Omar Arnaout, MD

Assistant Professor of Neurosurgery

Harvard Medical School

Boston, Massachusetts

75: Artificial Intelligence and Big Data in Neurosurgery

152: Basic Principles of Skull Base Surgery

170: Ventricular Tumors

174: Vestibular Schwannomas

Paul M. Arnold, MD, FACS

Professor and Chair

Department of Neurosurgery

University of Illinois Carle College of Medicine

Urbana, Illinois

339: Evaluation and Treatment of C2 (Axis) Fractures and Instability

Rachid Assina, RPh, MD

Assistant Professor of Neurological Surgery

Rutgers New Jersey Medical School

Newark, New Jersey

33: Brain Retraction

Oskar C. Aszmann, MD, PhD

Professor of Plastic and Reconstructive Surgery

Clinical Laboratory for Bionic Extremity Reconstruction

Department of Surgery

Medical University of Vienna

Vienna, Austria

287: Neuroelectronic Systems

Frank J. Attenello III, MD, MS

Clinical Instructor

Department of Neurological Surgery

Keck School of Medicine of the University of Southern California

Los Angeles, California

21: Surgical Planning

Albert Attia, MD

Associate Professor of Radiation Oncology and Neurosurgery

Vanderbilt University Medical Center

Nashville, Tennessee

292: Radiation Therapy Techniques

Anthony M. Avellino, MD, MBA

Assistant Vice President for Health Sciences

Chief Clinical and Medical Officer

Michigan State University

East Lansing, Michigan

Overview and Controversies (Pediatrics)

229: Cerebrospinal Fluid Devices

Issam A. Awad, MD, MSc, FACS

The John Harper Seeley Professor of Neurosurgery

Department of Surgery

The University of Chicago Pritzker School of Medicine

Chicago, Illinois

423: Nonlesional Spontaneous Intracerebral Hemorrhage

Temitayo O. Ayantayo, MB, BS

Medical Officer

RNZ Neuroscience

Lagos, Nigeria

281: Management of Acute Peripheral Nerve Injuries

Edward R. Bader, MBChB

Clinical Research Fellow

Department of Neurosurgery

Montefiore Medical Center

Bronx, New York; University of Aberdeen School of Medicine

Aberdeen, United Kingdom

213: Cranial Dysraphisms: Encephaloceles, Meningoceles, and Cranial Dermal Sinus Tracts

Jetan H. Badhiwala, MD

Resident Physician

Division of Neurosurgery

University of Toronto Faculty of Medicine

Toronto, Ontario, Canada

227: Ventricular Shunting Procedures

321: Evaluation and Treatment of Degenerative Cervical Myelopathy

Joachim M. Baehring, MD, DSc

Professor of Neurology and Neurosurgery

Yale School of Medicine

New Haven, Connecticut

161: Unusual Gliomas

Anto I. Bagic´, MD, PhD

Professor of Neurology and Neurosurgery

Chief, Epilepsy Division

Department of Neurology

Director, University of Pittsburgh

Comprehensive Epilepsy Center (UPCEC)

Director, MEG Epilepsy Program

Chief Scientific Advisor, MEG Research

Brain Mapping Center

University of Pittsburgh School of Medicine

Pittsburgh, Pennsylvania

86: Magnetoencephalography/Magnetic Source Imaging

Stephen J. Bagley, MD, MSCE

Assistant Professor of Medicine

Division of Hematology-Oncology

Perelman School of Medicine at the University of Pennsylvania

Abramson Cancer Center

Hospital of the University of Pennsylvania

Philadelphia, Pennsylvania

140: Angiogenesis and Brain Tumors: Scientific Principles, Current Therapy, and Future Directions

Michael Y. Bai

Department of Neurosurgery

Prince of Wales Hospital

Sydney, New South Wales, Australia

155: Endoscopic Approaches to Brain Tumors

Julian E. Bailes, MD

Clinical Professor of Medicine and Chair

Department of Neurosurgery

NorthShore University HealthSystem

Evanston, Illinois; Clinical Professor of Medicine

University of Chicago Pritzker School of Medicine

Chicago, Illinois

385: Sport-Related Concussion

Mark Bain, MD, MS

Staff Neurosurgeon

Cerebrovascular Center

Head, Cerebrovascular and Endovascular Surgical Neuroradiology Program

Cleveland Clinic Foundation Cleveland, Ohio

433: Endovascular Flow Diversion for Intracranial Aneurysms

Turner Baker, PhD Candidate

Project Manager

Sinai Bio

Design

Mount Sinai Health System

New York, New York

28: Robotics in Cranial Neurosurgery

Perry A. Ball, MD

Professor of Surgery and Anesthesiology

Geisel School of Medicine at Dartmouth Dartmouth-Hitchcock Medical Center

Lebanon, New Hampshire

Overview and Controversies (Introduction and General Neurosurgery)

35: Principles of Neurocritical Care

Leomar Y. Ballester, MD, PhD

Assistant Professor of Pathology and Laboratory Medicine

Assistant Professor of Neurosurgery

University of Texas Health Science Center at Houston Houston, Texas

133: Brain Tumors: An Overview of Current Histopathologic and Genetic Classifications

Ramani Balu, MD, PhD

Assistant Professor of Neurology Division of Neurocritical Care Perelman School of Medicine at the University of Pennsylvania Philadelphia, Pennsylvania

390: Electrophysiologic Monitoring for Traumatic Brain Injury

Vin Shen Ban, MB, BChir, MRCS, MSc

Resident Physician

Department of Neurological Surgery

University of Texas Southwestern Medical Center

Dallas, Texas

442: Microsurgery of Basilar Apex Aneurysms

Tanyeri Barak, MD

Associate Research Scientist

Department of Neurosurgery

Yale School of Medicine

New Haven, Connecticut

424: Genetics of Intracranial Aneurysms

Jacob F. Baranoski, MD

Resident Physician

Department of Neurosurgery

Barrow Neurological Institute

St. Joseph’s Hospital and Medical Center

Phoenix, Arizona

431: Endovascular Approaches to Narrow-necked Intracranial Aneurysms

459: Natural History of Cavernous Malformations

Nicholas M. Barbaro, MD

Professor of Neurological Surgery

University of Texas at Austin

Indianapolis, Indiana

97: Radiosurgical Treatment for Epilepsy

Sean M. Barber, MD

Assistant Professor of Neurosurgery

Houston Methodist Research Institute

Weill Cornell Medical College

Houston, Texas

64: Stem Cell Biology in the Central Nervous System

Frederick G. Barker II, MD

Professor of Neurosurgery

Harvard Medical School;

Attending Neurosurgeon

Massachusetts General Hospital

Boston, Massachusetts

53: Postoperative Infections of the Head and Brain

148: Brain Tumor Outcome Studies: Design and Interpretation

Gene H. Barnett, MD, MBA

Professor of Neurological Surgery

Director, The Rose Ella Burkhardt Brain

Tumor and Neuro-Oncology Center

Associate Dean of Faculty Affairs

Cleveland Clinic Lerner College of Medicine of Case Western Reserve University Cleveland. Ohio

154: Surgical Navigation for Brain Tumors

Constance M. Barone, MD, FACS

Barone’s Cosmetic Surgery Center

San Antonio, Texas

221: Endoscopic Treatment of Craniosynostosis

Daniel Louis Barrow, MD

Pamela R. Rollins Professor and Chairman

Department of Neurosurgery

Emory University School of Medicine

Atlanta, Georgia

440: Surgical Management of Middle Cerebral Artery Aneurysms

Jaafar Basma, MD

Resident Physician

Department of Neurosurgery

University of Tennessee Health Sciences Center

Memphis, Tennessee

31: Visualization and Optics in Neurosurgery

Tracy T. Batchelor, MD

Miriam Sydney Joseph Professor of Neurology

Harvard Medical School

Chair, Department of Neurology

Brigham and Women’s Hospital

Boston, Massachusetts

Overview and Controversies (Oncology)

168: Primary Central Nervous System Lymphomas

H. Hunt Batjer, MD, FAANS, FACS

Professor and Chair

Department of Neurological Surgery

University of Texas Southwestern Medical Center

Dallas, Texas

442: Microsurgery of Basilar Apex Aneurysms

Michael S. Beattie, PhD

Professor of Neurological Surgery

Director of Research, Department of Neurological Surgery

Brain and Spinal Injury Center

University of California, San Francisco School of Medicine

San Francisco, California

376: Animal Models of Traumatic Brain Injury

Andrew Beaumont, MD, PhD

Neurosurgeon and Clinical Director

Aspirus Spine and Neuroscience

Department

Aspirus Wausau Hospital

Wausau, Wisconsin

69: Physiology of the Cerebrospinal Fluid and Intracranial Pressure

Thomas L. Beaumont, MD, PhD

Assistant Professor of Neurological Surgery

University of California, San Diego

La Jolla, California

171: Colloid Cysts of the Third Ventricle

Joshua B. Bederson, MD

Professor and Chairman

Department of Neurosurgery

Icahn School of Medicine at Mount Sinai

The Mount Sinai Health System

New York, New York

27: Surgical Simulation

32: Microscope Integration and Heads-Up Display in Brain Surgery

Puneet Belani, MD

Assistant Professor of Diagnostic, Molecular and Interventional Radiology.

Icahn School of Medicine at Mount Sinai

New York, New York

12: Physiologic Evaluation of the Brain With Magnetic Resonance Imaging

Allan J. Belzberg, MD, FRCSC

Professor of Neurosurgery and Plastic & Reconstructive Surgery

The George J. Heuer Professor Director, Peripheral Nerve Surgery

Co-Director, Neurosurgery Pain Research Institute

Johns Hopkins Medical Institutions

Baltimore, Maryland

Overview and Controversies (Peripheral Nerve)

282: Early Management of Brachial Plexus Injuries

285: Benign and Malignant Tumors of the Peripheral Nerve

Arnau Benet, MD

Resident Physician Department of Neurosurgery

Barrow Neurological Institute

Phoenix, Arizona

3: Surgical Anatomy of the Skull Base

Sharona Ben-Haim, MD

Assistant Professor of Neurosurgery University of California, San Diego La Jolla, California

201: Neurosurgical Management of Intractable Pain

Alejandro Berenstein, MD

Professor of Radiology, Neurosurgery and Pediatrics, Icahn School of Medicine at Mount Sinai Center for Cerebrovascular Diseases

Mount Sinai Health System

New York, New York

247: Vein of Galen Aneurysmal Malformation

Sarah L. Berga, MD

Professor and Chair

Department of Obstetrics and Gynecology

University at Buffalo Jacobs School of Medicine and Biomedical Sciences; Medical Director

Obstetrics and Gynecology and Women’s Health Program Development

Oishei Children’s Hospital/Kaleida Health

Buffalo, New York

48: Systemic and Central Nervous System Changes During Pregnancy

Mitchel S. Berger, MD

Professor and Chair

Department of Neurological Surgery

University of California San Francisco School of Medicine

San Francisco, California

6: Improving Patient Safety

158: Low-Grade Gliomas: Diffuse Astrocytoma and Oligodendroglioma

Marvin Bergsneider, MD

Professor of Neurosurgery

David Geffen School of Medicine at University of California Los Angeles

Ronald Reagan UCLA Medical Center

Los Angeles, California

44: Shunting

Joshua D. Bernstock, MD, PhD, MPH

Resident Physician

Department of Neurosurgery

Harvard Medical School

Brigham and Women’s Hospital

Boston, Massachusetts

152: Basic Principles of Skull Base Surgery

Sanjay Bhatia, MBBS, MCh

Associate Professor of Neurosurgery

West Virginia University

Morgantown, West Virginia

341: Evaluation and Treatment of Cervicothoracic Junction Injuries

Wenya Linda Bi, MD, PhD

Assistant Professor of Neurosurgery

Department of Neurosurgery

Harvard Medical School

Brigham and Women’s Hospital

Boston, Massachusetts

173: Mesenchymal Nonmeningothelial Tumors

175: Pituitary Tumors: Functioning and Nonfunctioning

228: Neuroendoscopy

Mark G. Bigder, MD, MPH Clinical Instructor in Neurosurgery

Stanford University School of Medicine

Stanford, California

456: Surgical and Radiosurgical Management of Grade IV and V Arteriovenous Malformations

Philippe Bijlenga, MD, PhD

Assistant Professor

Department of Neurosurgery

University Hospital of Geneva

Geneva, Switzerland

30: Augmented Reality as an Aid in Neurosurgery

William Bingaman, MD

Professor of Neurological Surgery

Cleveland Clinic Lerner College of Medicine of the Case Western Reserve University

Vice Chairman, Neurologic Institute

Director of Surgical Epilepsy

Epilepsy Center

Cleveland Clinic

Cleveland, Ohio

89: Intracranial Monitoring With Subdural Grids and Strips

Harjus S. Birk, MD

Resident Physician

Department of Neurosurgery

University of California San Francisco School of Medicine

San Francisco, California

67: Cellular and Molecular Responses in the Peripheral and Central Nervous System Following Axonal Injury

Allen T. Bishop, MD

Professor of Orthopedic and Neurologic Surgery

Mayo Clinic Alix School of Medicine

Consultant

Department of Orthopedic Surgery

Division of Hand Surgery

Mayo Clinic

Rochester, Minnesota

283: Secondary Procedures for Brachial Plexus Injuries

Jaishri O. Blakeley, MD

Professor

Departments of Neurology, Oncology, and Neurosurgery

Johns Hopkins University School of Medicine

Baltimore, Maryland

146: Genetic Syndromes of Brain Tumors

Patric Blomstedt, MD, PhD

Professor of Stereotactic Functional Neurosurgery

Consultant Neurosurgeon

Department of Clinical Neuroscience

University Hospital of Northern Sweden

Umeå, Sweden

109: Surgical Management of Tremor

Rachel Blue, MD

Resident Physician

Department of Neurosurgery

Perelman School of Medicine at the University of Pennsylvania

Philadelphia, Pennsylvania

394: Cranioplasty

Scott Blumenthal, MD

Deputy Editor, European Spine Journal; Clinical Assistant Professor of Orthopaedic Surgery

University of Texas Southwestern School of Medicine

Dallas, Texas;

Co-Director, Center for Disc

Replacement

Texas Back Institute

Plano, Texas

356: Lumbar Disk Arthroplasty

Alessandro Boaro, MD

Clinical Fellow

Department of Neurosurgery

Harvard Medical School

Brigham and Women’s Hospital

Boston, Massachusetts

75: Artificial Intelligence and Big Data in Neurosurgery

James V. Boddu, MD

Resident Physician

Department of Neurosurgery

University of Miami Miller School of Medicine

Miami, Florida

366: Spinal Osteotomies

Angela Bohnen, MD

Associate Surgeon Department of Neurological Surgery

Mayo Clinic Jacksonville, Florida

159: Malignant Gliomas: Anaplastic Astrocytoma, Glioblastoma, Gliosarcoma, and Anaplastic Oligodendroglioma

Arnold P. Bok, MBChB, MMed, FCSSA, FRACS

Department of Neurological Surgery

Auckland City Hospital

Auckland, New Zealand

25: Positioning for Spine Surgery

Myles D. Boone, MD, MPH

Assistant Professor of Anesthesiology and Neurology

Geisel School of Medicine at Dartmouth Associate Medical Director, Neurocritical Care

Dartmouth Hitchcock Medical Center

Lebanon, New Hampshire

35: Principles of Neurocritical Care

Frederick A. Boop, MD

Professor and Chairman Department of Neurosurgery

University of Tennessee Health Science Center;

Chief, Pediatric Neurosurgery

St Jude Children’s Research Hospital

Memphis, Tennessee

237: Pediatric Supratentorial Hemispheric Tumors

Bronek M. Boszczyk, PD Dr.med. Consultant Spinal Surgeon Centre for Spinal Studies and Surgery

Queen’s Medical Centre

Nottingham University Hospitals NHS Trust

Nottingham, United Kingdom

330: Evaluation and Treatment of Rheumatoid Arthritis and Inflammatory Spinal Diseases

Susan M. Bowyer, PhD

Assistant Professor of Neurology

Wayne State University School of Medicine; Senior Scientist

Department of Neurology

Henry Ford Hospital Detroit, Michigan; Adjunct Professor of Physics

Oakland University

Rochester, Michigan

86: Magnetoencephalography/Magnetic Source Imaging

Bledi C. Brahimaj, MD

Resident Physician

Rush University Medical Center

Chicago, Illinois

92: Intraoperative Mapping and Monitoring for Cortical Resection

96: Palliative Procedures for DrugResistant Epilepsy

Henry Brem, MD

Harvey Cushing Professor and Director Department of Neurosurgery Professor of Neurosurgery, Ophthalmology, Oncology, and Biomedical Engineering

Johns Hopkins University School of Medicine; Neurosurgeon-in-Chief

Johns Hopkins Medical Institutions Director, Hunterian Neurosurgical Research Center

Baltimore, Maryland

Overview and Controversies (Oncology)

151: Basic Principles of Cranial Surgery for Brain Tumors

Steven Brem, MD

Professor of Neurosurgery

Perelman School of Medicine at the University of Pennsylvania Chief, Neurosurgical Oncology

Co-Director, Penn Brain Tumor Center

Abramson Cancer Center

Hospital of the University of Pennsylvania

Philadelphia, Pennsylvania

140: Angiogenesis and Brain Tumors: Scientific Principles, Current Therapy, and Future Directions

Jacqueline C. Bresnahan, PhD

Professor Emeritus of Neurological Surgery

Brain and Spinal Injury Center

University of California, San Francisco School of Medicine

San Francisco, California

376: Animal Models of Traumatic Brain Injury

Waleed Brinjikji, MD

Assistant Professor of Neurosurgery and Radiology

Mayo Clinic

Rochester, Minnesota

344: Evaluation and Treatment of Osteoporotic Fractures (Cement Augmentation)

Benjamin H. Brinkmann, PhD

Associate Professor of Neurology

Mayo Clinic

Rochester, Minnesota

85: Single-Photon Emission Computed Tomography in Epilepsy Surgery Evaluation

Andrei Brînzeu, MD, MSc, PhD

Associate Professor of Neurosurgery

University of Medicine and Pharmacy

“Victor Babes” Timisoara

Timisoara, Romania

208: Dorsal Root Entry Zone Lesions for Pain

Gavin W. Britz, MD, MPH, MBA

Chair of Neurosurgery

Houston Methodist Hospital

Houston, Texas

152: Basic Principles of Skull Base Surgery

Overview and Controversies

(Microsurgical and Interventional Treatment of Vascular Diseases)

425: Natural History of Cerebral Aneurysms

435: Surgical Approaches to Intracranial Aneurysms

447: Traumatic Cerebral Aneurysms Secondary to Penetrating Intracranial Injuries

Douglas L. Brockmeyer, MD, FAAP

Professor of Neurosurgery

Chief, Division of Pediatric Neurosurgery

University of Utah School of Medicine

Salt Lake City, Utah

262: Surgical Management of the Pediatric Subaxial Cervical Spine

Desmond A. Brown, MD

Resident Physician

Department of Neurologic Surgery

Mayo Clinic

Rochester, Minnesota

403: Cerebral Blood Flow and Metabolism and Cerebral Ischemia

Justin M. Brown, MD

Associate Professor of Neurosurgery

Harvard Medical School

Massachusetts General Hospital

Boston, Massachusetts

288: Peripheral Nerve Surgery for Central Nervous System Disorders

Matthew T. Brown, MD

Neurosurgeon

Midlands Orthopaedics and Neurosurgery

Columbia, South Carolina

31: Visualization and Optics in Neurosurgery

Robert D. Brown, Jr., MD, MPH

John T. and Lillian Mathews Professor of Neuroscience

Department of Neurology

Mayo Clinic

Rochester, Minnesota

451: Epidemiology and Natural History of Cerebral Vascular Malformations

Jeffrey N. Bruce, MD, FACS

Edgar M. Housepian Professor

Vice Chairman of Academic Affairs

Department of Neurological Surgery

Columbia University Vagelos College of Physicians and Surgeons

New York-Presbyterian/Columbia

University Irving Medical Center

New York, New York

164: Pineal Tumors

Karl C. Bruckman, MD, DDS

Assistant Professor of Plastic Surgery

Stanford University School of Medicine

Palo Alto, California

219: Nonsyndromic Craniosynostosis: Introduction and Single-Suture Synostosis

Alexis Bruhat, MS, MBE

Project Manager

Sinai BioDesign

Mount Sinai Health System

New York, New York

28: Robotics in Cranial Neurosurgery

Janice E. Brunstrom-Hernandez, MD

Director, 1 CP Place, PLLC

Plano, Texas;

Associate Professor of Neurology

Washington University School of Medicine in St. Louis

St. Louis, Missouri

268: Clinical Features and Management of Cerebral Palsy

Andrew Brunswick, MD

Resident Physician

Department of Neurosurgery

New York University School of Medicine

NYU Langone Medical Center

New York, New York

243: Neurocutaneous Tumor Syndromes

Amy K. Bruzek, MD, MS

Resident Physician Department of Neurosurgery

University of Michigan Medical School

Ann Arbor, Michigan

163: Central Nervous System Embryonal Tumors

Ian A. Buchanan, MD

Resident Physician

Department of Neurosurgery

University of Southern California

Keck School of Medicine

Los Angeles, California

139: Basic Science of Brain Metastases

Karol P. Budohoski, MD, PhD

Consultant Neurosurgeon

Department of Neurosurgery

Cambridge University Hospitals

Addenbrookes Hospital

NIHR Global Health Research Group on Neurotrauma

University of Cambridge

Cambridge, United Kingdom

391: Surgical Management of Traumatic Brain Injury

Thomas J. Buell, MD

Resident Physician

Department of Neurosurgery

University of Virginia Health System

Charlottesville, Virginia

25: Positioning for Spine Surgery

265: Thoracolumbar Spinal Disorders in Pediatric Patients

351: Evaluation and Treatment of Adult Scoliosis and Sagittal Plane Deformity

353: Treatment of High-Grade Spondylolisthesis

András Büki, MD, PhD, DSc

Department of Neurosurgery

Medical School and Neurotrauma

Research Group

Szentágothai Research Centre

University of Pécs

Pécs, Hungary

379: Traumatic Brain Injury: Proteomic Biomarkers

Adomas Bunevicius, MD, PhD

Clinical Fellow

Department of Neurosurgery

University of Virginia

Charlottesville, Virginia

199: Stereotactic Radiosurgery for Trigeminal Neuralgia

Overview and Controversies (Radiation)

Kim J. Burchiel, MD, FACS

John Raaf Professor of Neurological Surgery

Professor of Anesthesiology and Perioperative Medicine

Oregon Health & Science University

Portland, Oregon

Overview and Controversies (Pain)

198: Percutaneous Procedures for Trigeminal Neuralgia

200: Microvascular Decompression for Trigeminal Neuralgia

205: Evidence Base for Destructive Procedures

208: Dorsal Root Entry Zone Lesions for Pain

Mohamad Bydon, MD

Professor of Neurosurgery

Mayo Clinic

Rochester, Minnesota

51: Brain Tumors During Pregnancy

344: Evaluation and Treatment of Osteoporotic Fractures (Cement Augmentation)

Richard W. Byrne, MD

Professor of Neurosurgery

Rush University Medical Center

Chicago, Illinois

92: Intraoperative Mapping and Monitoring for Cortical Resection

96: Palliative Procedures for DrugResistant Epilepsy

Raysa Cabrejo, MD, MHS

Resident Physician

Department of Surgery

Yale New Haven Hospital

New Haven, Connecticut

23: Incisions and Closures

Ivan Cabrilo, MD

Neurosurgeon

Department of Neurosurgery

University Hospital of Geneva

Geneva, Switzerland

30: Augmented Reality as an Aid in Neurosurgery

Daniel P. Cahill, MD, PhD

Associate Professor of Neurosurgery

Harvard Medical School

Massachusetts General Hospital

Dana-Farber Harvard Cancer Center

Boston, Massachusetts

148: Brain Tumor Outcome Studies: Design and Interpretation

Justin M. Caplan, MD

Assistant Professor of Neurosurgery

Johns Hopkins University School of Medicine

Baltimore, Maryland

438: Microsurgery of Anterior Communicating Artery Aneurysms

Andrew P. Carlson, MD, MS-CR Assistant Professor of Neurosurgery

University of New Mexico School of Medicine

Albuquerque, New Mexico

390: Electrophysiologic Monitoring for Traumatic Brain Injury

Julián Carrión-Penagos, MD

Postdoctoral Fellow Department of Surgery

The University of Chicago Pritzker School of Medicine

Chicago, Illinois

423: Nonlesional Spontaneous Intracerebral Hemorrhage

Benjamin W. Carroll, MD, MDiv Resident Physician

Department of Neurosurgery

University of Mississippi Medical Center

Jackson, Mississippi

245: Skull Lesions in Children

Gregory D. Cascino, MD Professor of Neurology

Mayo Clinic

Rochester, Minnesota

85: Single-Photon Emission Computed Tomography in Epilepsy Surgery Evaluation

Leandro Castaneyra-Ruiz, PhD

Postdoctoral Research Associate Department of Neurosurgery

Washington University in St. Louis School of Medicine

St. Louis, Missouri

226: Experimental Hydrocephalus

Frederic Castinetti, MD, PhD

Assistant Professor of Endocrinology Aix-Marseille University

Assistance Publique Hopitaux de Marseille

Marseille, France

299: Radiosurgery for Benign Intracranial Tumors

Daniel D. Cavalcanti, MD, PhD

Vascular and Endovascular Neurosurgeon

Hartford HealthCare

Bridgeport, Connecticut

444: Medical, Microsurgical, and Interventional Treatment of Infectious Aneurysms

C. Michael Cawley, MD Professor of Neurosurgery

Emory University School of Medicine

Atlanta, Georgia

458: Treatment of Other Intracranial Dural Arteriovenous Fistulas

Ibolja Cernak, MD, PhD, ME, MHS

Professor of Pathophysiology and Neuroscience

Department of Biomedical Sciences

Mercer University School of Medicine

Macon, Georgia

396: Blast-Induced Neurotrauma

Justin S. Cetas, MD, PhD

Professor of Neurological Surgery

Oregon Health & Science University; Chief of Neurosurgery

Operative Care Division

Portland VA Medical Center

Portland, Oregon

205: Evidence Base for Destructive Procedures

Michael D. Chan, MD

Associate Professor and Vice Chairman Department of Radiation Oncology Co-Director, Gamma Knife Program

Wake Forest School of Medicine

Winston-Salem, North Carolina

292: Radiation Therapy Techniques

Vivien Ka-Ying Chan, MD

Resident Physician

Division of Neurosurgery

University of Alberta Faculty of Medicine

Edmonton. Alberta, Canada; Research Fellow

Department of Neurosurgery

University of Toronto Faculty of Medicine

Toronto, Ontario, Canada

448: Medical Management of Cerebral Vasospasm

Chih-Chang Chang, MD

Research Fellow

Department of Neurological Surgery

University of California, San Francisco School of Medicine

San Francisco, California; Department of Neurosurgery

Neurological Institute

Taipei Veterans General Hospital; National Yang Ming University School of Medicine

Taipei, Taiwan

355: Cervical Arthroplasty

Louis Chang, MD

Assistant Professor of Neurological

Surgery

Weill Cornell Medicine

New York, New York

362: Posterior Thoracic and Lumbar Instrumentation

368: Minimally Invasive Decompression Techniques

Steven D. Chang, MD

Robert C. and Jeannette Powell Professor

Department of Neurosurgery

Stanford School of Medicine

Stanford, California

Overview and Controversies (Radiation)

302: Radiosurgery for Benign Spine Tumors and Spinal Vascular Malformations

456: Surgical and Radiosurgical Management of Grade IV and V Arteriovenous Malformations

Fady T. Charbel, MD

Professor and Head

Department of Neurosurgery

University of Illinois at Chicago Chicago, Illinois

411: Neurovascular Imaging

418: Extracranial Vertebral Artery Diseases

Raphaële Charest-Morin, MD, FRCSC

Clinical Assistant Professor Division of Spine Surgery

Department of Orthopaedic Surgery

University of British Columbia

Vancouver, British Columbia, Canada

326: Evaluation and Treatment of Primary Malignant Tumors of the Axial Skeleton

Aswin Chari, MA, BMBCh, MRCS

GOSH Charity Surgical Scientist Fellow and PhD Candidate Department of Developmental Neurosciences

UCL Great Ormond Street Institute of Child Health

University College London

Honourary Specialist Registrar Department of Neurosurgery

Great Ormond Street Hospital

London, United Kingdom

47: Medical and Surgical Management of Chronic Subdural Hematomas

Navjot Chaudhary, MD Neurosurgeon

University of British Columbia

Vancouver, British Columbia

302: Radiosurgery for Benign Spine Tumors and Spinal Vascular Malformations

Patrick Chauvel, MD

Professor of Medicine

Lerner College of Medicine

Case Western Reserve University;

Staff Neurologist

Epilepsy Center

Cleveland Clinic

Cleveland, Ohio

90: Intracranial Monitoring: Stereoelectroencephalography Recording

Kevin S. Chen, MD

Great Lakes Neurosurgical Associates

Grand Rapids, Michigan;

Adjunct Assistant Professor of Neurosurgery

University of Michigan Medical School

Ann Arbor, Michigan

273: Peripheral Neuropathies

Liang Chen, MD, PhD

Professor

Hand Surgery Department

Huashan Hospital of Fudan University

Shanghai, China

Overview and Controversies (Peripheral Nerve)

279: Techniques in Nerve Reconstruction and Repair

280: Nerve Transfers

Joseph Cheng, MD, MS

Frank H. Mayfield Professor and Chair Department of Neurosurgery

University of Cincinnati College of Medicine Cincinnati, Ohio

306: Spinal Biomechanics and Basics of Spinal Instrumentation

Jacob Cherian, MD

Assistant Professor

Department of Neurosurgery

University of Maryland School of Medicine

Baltimore, Maryland

440: Surgical Management of Middle Cerebral Artery Aneurysms

458: Treatment of Other Intracranial Dural Arteriovenous Fistulas

Kenneth M.C. Cheung, MBBS(UK), MD(HK), FRCS, FHKCOS, FHKAM(Orth)

Jessie Ho Professor in Spine Surgery

Head, Department of Orthopaedics and Traumatology

The University of Hong Kong

Hong Kong, China

360: Anterior Thoracic Instrumentation

Cletus Cheyuo, MD, PhD

Resident Physician

Department of Neurosurgery

West Virginia University School of Medicine

Morgantown, West Virginia

122: Surgery for Obsessive-Compulsive Disorder

Veronica L. Chiang, MD

Professor of Neurosurgery

Yale School of medicine

New Haven, Connecticut

295: Combining Ionizing Radiation and Systemic Therapies for Treatment of Brain Metastases

Peter A. Chiarelli, MD, DPhil

Assistant Professor of Clinical Neurological Surgery

University of Southern California Keck School of Medicine; Attending Physician

Department of Neurosurgery

Children’s Hospital Los Angeles Los Angeles, California

211: Neurocritical Care in Children

E. Antonio Chiocca, MD, PhD, FAANS

Harvey W. Cushing Professor of Neurosurgery

Harvard Medical School; Neurosurgeon-in-Chief and Chair Department of Neurosurgery

Co-Director, Institute for the Neurosciences

Brigham and Women’s Hospital Boston, Massachusetts

Overview and Controversies (Oncology)

170: Ventricular Tumors

Rohan V. Chitale, MD

Associate Professor of Neurological Surgery and Radiology

Vanderbilt University Medical Center

Nashville, Tennessee

441: Microsurgery of Vertebral Artery and Posterior Inferior Cerebellar Artery Aneurysms

Catherine Cho, MD, MSCR

Clinical Associate Professor Departments of Neurology and Otolaryngology

NYU Langone Medical Center

New York, New York

106: Patient Selection Criteria for Deep Brain Stimulation in Movement Disorders

Heejung Choi, MD, D.ABA

Assistant Professor of Anesthesiology

Feinberg School of Medicine

Northwestern University Chicago, Illinois

194: Pharmacologic Treatment of Pain

Dean Chou, MD

Professor of Neurosurgery

University of California, San Francisco School of Medicine

San Francisco, California

4: Surgical Anatomy of the Spine Overview and Controversies (Spine)

350: Evaluation and Treatment of Scheuermann Kyphosis

Cindy W. Christian, MD

Professor of Pediatrics

Perelman School of Medicine at the University of Pennsylvania

Chair, Child Abuse and Neglect Prevention

The Children’s Hospital of Philadelphia

Philadelphia, Pennsylvania

251: Inflicted Trauma (Child Abuse)

Peter A. Christiansen, MD

Resident Physician

Department of Neurosurgery

University of Virginia Health System

Charlottesville, Virginia

25: Positioning for Spine Surgery

317: Evaluation and Treatment of Thoracic Disk Herniation

351: Evaluation and Treatment of Adult Scoliosis and Sagittal Plane Deformity

Ephraim W. Church, MD

Assistant Professor of Neurosurgery, Radiology, and Neurology

Director, Cerebral Revascularization Program

Department of Neurosurgery

Penn State Health

Hershey, Pennsylvania

413: The Natural History and Medical Management of Carotid Occlusive Disease

Jennifer L. Clarke, MD, MPH

Professor of Neurology and Neurological Surgery

University of California, San Francisco

San Francisco, California

142: Epidemiology of Brain Tumors

Daniel R. Cleary, MD, PhD Resident Physician

Department of Neurosurgery

University of California, San Diego

La Jolla, California

191: Anatomy and Physiology of Pain

James E. Clune, MD

Assistant Professor of Surgery

Division of Plastic Surgery

Yale School of Medicine

New Haven, Connecticut; Chief, Division of Plastic Surgery

Department of Surgery

West Haven VA Hospital

West Haven, Connecticut

23: Incisions and Closures

188: Scalp Tumors

Justin D. Cohen, MD

Resident Physician

Department of Neurosurgery

Cedars Sinai Medical Center

Los Angeles, California

417: Nonatherosclerotic Carotid Lesions

Or Cohen-Inbar, MD PhD

Assistant Professor of Neurological Surgery

University of Pittsburgh School of Medicine

Pittsburgh, Pennsylvania;

Assistant Professor of Neurological Surgery

University of Virginia School of Medicine

Charlottesville, Virginia; Neurological Surgery

UPMC Western Maryland

Cumberland, Maryland

Overview and Controversies (Introduction and General Neurosurgery)

39: Brain Tumor Management in the Geriatric Patient

Roberto Colasanti, MD

Department of Neurosurgery

Università Politecnica delle Marche Ancona, Italy; Department of Neurosurgery

Maurizio Bufalini Hospital

AUSL della Romagna Cesena, Italy

179: Overview of Skull Base Tumors

John M. Collins, MD, PhD

Assistant Professor of Radiology

University of Chicago Pritzker School of Medicine

Chicago, Illinois

58: Neurological Manifestations of HIV and AIDS

Youssef G. Comair, MD, FRCSC Professor and Chief Division of Neurosurgery

The American University of Beirut Beirut, Lebanon; Adjunct Professor of Neurosurgery

Baylor College of Medicine

Houston, Texas;

Visiting Professor of Neurosurgery

Johns Hopkins University School of Medicine

Baltimore, Maryland

95: Resections for Extratemporal Epilepsy

Andrew K.P. Conner, MD

Assistant Professor Department of Neurosurgery

The University of Oklahoma Health Sciences Center

Oklahoma City, Oklahoma

111: Deep Brain Stimulation for Parkinson Disease

E. Sander Connolly, Jr., MD, FACS

Byron Stookey Professor of Neurological Surgery

Chair, Department of Neurosurgery

Columbia University Vagelos College of Physicians & Surgeons

Director, Cerebrovascular Research Laboratory

Surgical Director, Neuro-Intensive Care Unit

New York-Presbyterian Columbia University Medical Center

New York, New York

Overview and Controversies

(Microsurgical and Interventional Treatment of Vascular Diseases)

439: Microsurgery of Distal Anterior Cerebral Artery Aneurysms

Jared B. Cooper, MS, MD

Resident Physician

Department of Neurosurgery

Westchester Medical Center

Valhalla, New York

463: Endovascular Treatment of Spinal Vascular Malformations

Daniel Montie Corcos, PhD, MA, MS, BEd

Professor of Physical Therapy and Human Movement Sciences

Northwestern University Feinberg School of Medicine

Chicago, Illinois

127: Management of Spasticity by Central Nervous System Infusion Techniques

Domagoj Coric, MD

Chief, Department of Neurosurgery

Carolinas Medical Center

Carolina Neurosurgery and Spine Associates

Charlotte, North Carolina

363: Posterior, Transforaminal, and Anterior Lumbar Interbody Fusion

Anthony B. Costa, PhD

Assistant Professor of Neurosurgery

Icahn School of Medicine at Mount Sinai

New York, New York

27: Surgical Simulation

32: Microscope Integration and Heads-Up Display in Brain Surgery

William T. Couldwell, MD, PhD

Professor and Chair

Department of Neurosurgery

University of Utah School of Medicine

Salt Lake City, Utah

Overview and Controversies

(Introduction and General Neurosurgery)

24: Positioning for Cranial Surgery

34: Advantages and Limitations of Cranial Endoscopy

Peter B. Crino, MD, PhD

Professor and Chair

Department of Neurology

University of Maryland School of Medicine

Baltimore, Maryland

79: Malformations of Cortical Development

Andrew R. Crofton, PhD

Assistant Professor

Department of Anatomy

Case Western Reserve School of Medicine

Cleveland, Ohio

18: Coagulation for the Neurosurgeon

D. Kacy Cullen, PhD

Associate Professor of Neurosurgery

Perelman School of Medicine at the University of Pennsylvania

Philadelphia, Pennsylvania

374: Biomechanical Basis of Traumatic Brain Injury

Armin Curt, MD, FRCPC

Professor

Spinal Cord Injury Centre

Balgrist University Hospital

Zurich, Switzerland

345: Rehabilitation of Acute Spinal Cord Injury

Ralph G. Dacey, Jr., MD, FACS, FRCSI (Hon)

Henry G. and Edith R. Schwartz Professor and Chairman

Former Chairman

Department of Neurological Surgery

Washington University School of Medicine in St Louis

St Louis, Missouri

171: Colloid Cysts of the Third Ventricle

Rrita Daci, MD

Resident Physician

Department of Neurological Surgery

University of Massachusetts Medical School

Worcester, Massachusetts

41: Genetics of Idiopathic Normal Pressure Hydrocephalus

Andrew T. Dailey, MD

Professor of Neurosurgery

University of Utah School of Medicine

Salt Lake City, Utah

54: Postoperative Infections of the Spine Overview and Controversies (Spine)

Quintino Giorgio D’Alessandris, MD, PhD

Staff Neurosurgeon

Department of Neurosurgery

Fondazione Policlinico Universitario

A.Gemelli IRCSS

Rome, Italy

150: Frame and Frameless Stereotactic Brain Biopsy

Eyiyemisi C. Damisah, MD, MHS

Assistant Professor of Neurosurgery

Yale School of Medicine

New Haven, Connecticut

94A: Anteromedial Temporal Lobectomy

David J. Daniels, MD, PhD

Assistant Professor of Pediatric Neurosurgery

Assistant Professor of Pharmacology

Department of Neurologic Surgery

Mayo Clinic Rochester, Minnesota

237: Pediatric Supratentorial Hemispheric Tumors

Sunit Das, MD, PhD

Associate Professor of Neurosurgery

University of Toronto Faculty of Medicine

St. Michael’s Hospital

Toronto, Ontario, Canada

165: Medulloblastomas in Adults

Justin R. Davanzo, MD

Director of Neurocritical Care

Department of Neurosurgery

Allegheny Health Network

Pittsburgh, Pennsylvania

95: Resections for Extratemporal Epilepsy

378: Neurochemical Pathomechanisms in Traumatic Brain Injury

Carlos A. David, MD

Associate Professor of Neurosurgery

Tufts University School of Medicine

Boston, Massachusetts; Director, Cerebrovascular and Skull

Base Surgery

Department of Neurosurgery

Lahey Clinic Hospital

Burlington, Massachusetts

419: Microsurgical Management of Intracranial Occlusion Disease

David J. David, MD, FRCSE, FRCS, FRACS, FRCST

Professor of Craniomaxillofacial Surgery

School of Health and Medical Sciences

University of Adelaide

Adelaide, South Australia, Australia

398: Craniofacial Injuries

Benjamin Davidson, MD

Resident Physician

Division of Neurosurgery

University of Toronto Faculty of Medicine

Toronto, Ontario, Canada

123: Surgery for Major Depressive Disorder

Gavin A. Davis, MB.BS., FRACS(Neurosurgery)

Neurosurgeon Department of Neurosurgery Cabrini Hospital

Malvern, Victoria, Australia; Adjunct Professor University of Notre Dame Australia; Adjunct Clinical Professor Monash University; Research Associate

Murdoch Children’s Research Institute Melbourne, Victoria, Australia

385: Sport-Related Concussion

Arthur L. Day, MD

Co-Chairman, Professor, and Program Director

Director of Cerebrovascular Program Department of Neurosurgery

University of Texas at Houston Health Science Center

Houston, Texas

436: Microsurgery of Paraclinoid Aneurysms

Nicolas Dea, MD, MSc, FRCSC

Clinical Associate Professor of Neurosurgery

Division of Neurosurgery Department of Surgery

University of British Columbia Vancouver, British Columbia, Canada

326: Evaluation and Treatment of Primary Malignant Tumors of the Axial Skeleton

Giuseppe De Donato, MD Department of Otorhinolaryngology

San Carlo Borromeo University Hospital

Azienda Socio Sanitaria Territoriale (ASST) Santi Paolo e Carlo Milano, Italy

181: Head and Neck Paragangliomas

Stacie Deiner, MD

Assistant Professor of Anesthesiology, Neurosurgery, Geriatrics and Palliative Care

Icahn School of Medicine at Mount Sinai

New York, New York

38: The Geriatric Patient

Carlos De la Garza, MD

Resident Physician Department of Neurology

Baylor College of Medicine

Houston, Texas

389: Noninvasive Neuromonitoring for Traumatic Brain Injury

Nader Delavari, MD

Resident Physician Department of Neurosurgery

New York University Grossman School of Medicine

New York, New York

145: Endovascular Techniques for Tumor Embolization

444: Medical, Microsurgical, and Interventional Treatment of Infectious Aneurysms

Oscar H. Del Brutto, MD

Director, The Atahualpa Project

Universidad Espiritu Santo School of Medicine

Guayaquil, Ecuador

59: Parasitic Infections

Bradley N. Delman, MD, MS

Associate Professor of Diagnostic, Molecular and Interventional Radiology

The Icahn School of Medicine at Mount Sinai

New York, New York

12: Physiologic Evaluation of the Brain With Magnetic Resonance Imaging

Mahlon R. DeLong, MD

Professor of Neurology Emeritus

Emory University School of Medicine

Atlanta, Georgia

103: Rationale for Surgical Interventions in Movement Disorders

Franco DeMonte, MD, FRCSC, FACS Professor

Departments of Neurosurgery and Head and Neck Surgery

Mary Beth Pawelek Chair in Neurosurgery

University of Texas MD Anderson Cancer Center

Houston, Texas

182: Neoplasms of the Paranasal Sinuses

Evandro de Oliveira, MD† Professor of Neurosurgery

Mayo Clinic

Jacksonville, Florida; Director, Instituto de Ciências Neurológicas

São Paulo, Brazil

2: Surgical Anatomy of the Brain

Peter B. Derman, MD, MBA

Spine Surgeon

Texas Back Institute

Plano, Texas

356: Lumbar Disk Arthroplasty

Arati Desai, MD

Assistant Professor Medicine

Division of Hematology-Oncology

Perelman School of Medicine at the University of Pennsylvania

Co-Director, Penn Brain Tumor Center

Abramson Cancer Center

Hospital of the University of Pennsylvania

Philadelphia, Pennsylvania

140: Angiogenesis and Brain Tumors: Scientific Principles, Current Therapy, and Future Directions

Krutika Deshpande, MS

Doctoral Candidate

University of Southern California

Keck School of Medicine

Los Angeles, California

139: Basic Science of Brain Metastases

† Deceased.

Michele Diaz, RN, MS

PhD Nursing Student

Community Health Systems

University of California San Francisco

San Francisco, California

40: Traumatic Brain Injury in the Geriatric Patient

Ramon R. Diaz-Arrastia, MD, PhD

Presidential Professor of Neurology

Director, Traumatic Brain Injury

Clinical Research Center

Perelman School of Medicine at the University of Pennsylvania

Philadelphia, Pennsylvania

390: Electrophysiologic Monitoring for Traumatic Brain Injury

Anthony M. DiGiorgio, DO, MHA

Assistant Professor of Neurological Surgery

University of California San Francisco

San Francisco, California

37: Intracranial Pressure Monitoring

Michael L. DiLuna, MD, FAANS

Associate Professor of Neurosurgery and Pediatrics

Chief, Pediatric Neurosurgery

Yale School of Medicine

New Haven, Connecticut

161: Unusual Gliomas

Francesco DiMeco, MD

Director, Department of Neurosurgery

Istituto Nazionale Neurologico “C.Besta”

Full Professor of Neurosurgery

Department of Pathophysiology and Transplantation

University of Milan

Milan, Italy;

Assistant Professor (adjunct)

Department of Neurological Surgery

Johns Hopkins Medical School

Baltimore, Maryland

Overview and Controversies (Oncology)

135: Brain Tumor Stem Cells

Brian J. Dlouhy, MD

Assistant Professor of Neurosurgery

University of Iowa Hospitals and Clinics

Iowa City, Iowa

260: Developmental Anomalies of the Craniovertebral Junction and Surgical Management

270: Selective Dorsal Rhizotomy for Spastic Cerebral Palsy

Yücel Doğ ruel, MD

Resident Physician

Department of Neurosurgery

Pamukkale Üniversitesi

Denizli, Turkey

206: Dorsal Rhizotomy and Dorsal Root Ganglionectomy

Joseph H. Donahue, MD

Assistant Professor of Neuroradiology

University of Virginia School of Medicine

Charlottesville, Virginia

199: Stereotactic Radiosurgery for Trigeminal Neuralgia

294: Radiology of Radiation Techniques

Daniel A. Donoho, MD

Department of Neurological Surgery

Keck School of Medicine of the University of Southern California

Los Angeles, California

228: Neuroendoscopy

Amish H. Doshi, MD

Associate Professor of Radiology and Neurosurgery

The Icahn School of Medicine at Mount Sinai

New York, New York

12: Physiologic Evaluation of the Brain With Magnetic Resonance Imaging

Jens P. Dreier, MD

Professor and Senior Physician

Department of Neurology and Experimental Neurology

Center for Stroke Research

Berlin Charité – Universitätsmedizin

Berlin Berlin, Germany

390: Electrophysiologic Monitoring for Traumatic Brain Injury

Joseph Driver, MD

Resident Physician Department of Neurosurgery

Harvard Medical School

Brigham and Women’s Hospital

Boston, Massachusetts

173: Mesenchymal Nonmeningothelial Tumors

Alexander Drofa, MD, FRCSC

Cerebrovascular Neurosurgeon

Sanford Brain and Spine Center

Sanford Medical Center Fargo; Clinical Instructor of Surgery Department of Surgery University of North Dakota Fargo, North Dakota

433: Endovascular Flow Diversion for Intracranial Aneurysms

Andrew F. Ducruet, MD

Assistant Professor of Neurosurgery

Barrow Neurological Institute

St. Joseph’s Hospital and Medical Center

Phoenix, Arizona

406: Acute Surgical and Endovascular Management of Ischemic and Hemorrhagic Stroke

431: Endovascular Approaches to Narrow-necked Intracranial Aneurysms

Hugues Duffau, MD, PhD

Professor and Chairman

Department of Neurosurgery

Gui de Chauliac Hospital

Institute for Neuroscience of Montpellier, INSERM U1051

Saint Eloi Hospital

Montpellier University Medical Center

Montpellier, France

156: Awake Craniotomy and Intraoperative Mapping

Ann-Christine Duhaime, MD

Nicholas T. Zervas Professor of Neurosurgery

Harvard Medical School

Director, Pediatric Neurosurgery

Massachusetts General Hospital

Boston, Massachusetts

251: Inflicted Trauma (Child Abuse)

Aaron S. Dumont, MD

Charles B. Wilson Professor and Chair

Department of Neurological Surgery

Tulane University School of Medicine

New Orleans, Louisiana

Overview and Controversies

(Microsurgical and Interventional Treatment of Vascular Diseases)

464: Microsurgical Treatment of Spinal Vascular Malformations

John S. Duncan, DM, FRCP, FMedSci

Professor of Neurology

Department of Clinical and Experimental Epilepsy

University College London Queen Square Institute of Neurology

Consultant Neurologist

Department of Epilepsy

National Hospital for Neurology and Neurosurgery

London, United Kingdom; Professor of Neurology

Epilepsy MRI Centre

Chalfont Centre for Epilepsy

Chalfont St Peter, United Kingdom

88: Preoperative Functional Localization

Gavin P. Dunn, MD, PhD

Associate Professor

Departments of Neurological Surgery and Pathology and Immunology

Center for Human Immunology and Immunotherapy Programs

Washington University School of Medicine in St. Louis

St. Louis, Missouri

166: Intracranial Ependymomas in Adults

Ian F. Dunn, MD

Professor and Chairman

Department of Neurosurgery

University of Oklahoma Health Sciences Center

Oklahoma City, Oklahoma

166: Intracranial Ependymomas in Adults

175: Pituitary Tumors: Functioning and Nonfunctioning

176: Craniopharyngiomas in Adults

James H. Eberwine, PhD

Elmer Holmes Bobst Professor

Department of Systems Pharmacology and Experimental Therapeutics

Perelman School of Medicine at the University of Pennsylvania

Philadelphia, Pennsylvania

61: Molecular Biological Approaches for Understanding the Nervous System: A Primer for Neurosurgeons

Gerald W. Eckardt, MD

Staff Neurosurgeon

BayCare Clinic

Green Bay, Wisconsin

359: Posterior Subaxial and Cervicothoracic Instrumentation

Idara J. Edem, MD, MSc, FRCSC

Fellow, Skull Base Neurosurgical Oncology

Department of Neurosurgery

The University of Texas MD Anderson Cancer Center Houston, Texas

182: Neoplasms of the Paranasal Sinuses

Michael S.B. Edwards, MD

Lucile Packard Endowed Professor of Neurosurgery and Pediatrics

Stanford University School of Medicine

Stanford, California; Professor of Neurosurgery and Pediatrics

UC Davis Medical Center

Sacramento, California

238: Ependymomas

Emrah Egemen, MD, FEBNS

Assistant Professor of Neurosurgery

Pamukkale Üniversitesi

Denizli, Turkey

206: Dorsal Rhizotomy and Dorsal Root Ganglionectomy

Rachel Eisenbarth, BS

MD Candidate

University of Southern California

Keck School of Medicine

Los Angeles, California

139: Basic Science of Brain Metastases

Howard Eisenberg, MD

Raymond K. Thompson, MD Professor University of Maryland School of Medicine

Baltimore, Maryland

393: Surgical Management and Prognosis of Penetrating Brain Injury

J. Bradley Elder, MD

Associate Professor of Neurological Surgery

Director of Neurosurgical Oncology

The Ohio State University Wexner Medical Center

Columbus, Ohio

162: Local Therapies for Gliomas

Mohamed Samy Elhammady, MD

Professor of Neurosurgery

Cleveland Clinic

Abu Dhabi, United Arab Emirates

455: Microsurgery of Arteriovenous Malformations

W. Jeffrey Elias, MD

Professor of Neurosurgery and Neurology

University of Virginia School of Medicine

Charlottesville, Virginia

117: Transcranial Magnetic Resonance–Guided Focused Ultrasound Thalamotomy for Tremor

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