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SectionEditors
JaneC.Ballantyne,MD,FRCA
ProfessorofAnesthesiologyandPainMedicine UniversityofWashington
Seattle,Washington
NikolaiBogduk,BSc(Med),MB,BS,MD,PhD,DSc,MMed,FAFRM, FFPM(ANZCA)
EmeritusProfessorofPainMedicine
TheUniversityofNewcastle Newcastle,NewSouthWales,Australia
DavidJ.Copenhaver,MD,MPH
AssociateProfessor
DepartmentofAnesthesiologyandPainMedicine
DepartmentofNeurologicalSurgery
AssociateDirector,CenterforAdvancingPainRelief Director,CancerPainManagement
UniversityofCaliforniaatDavis Sacramento,California
EmadN.Eskandar,MD Professor
DepartmentofNeurosurgery
HarvardMedicalSchool
Boston,Massachusetts
ScottM.Fishman,MD
FullertonEndowedChairofPainMedicine
Chief,DivisionofPainMedicineandProfessorofAnesthesiology Director,CenterforAdvancingPainRelief DepartmentofAnesthesiologyandPainMedicine
UniversityofCalifornia,DavisSchoolofMedicine Sacramento,California
RollinM.Gallagher,MD,MPH
ClinicalProfessor
PsychiatryandAnesthesiology
PerelmanSchoolofMedicine,UniversityofPennsylvania Philadelphia,Pennsylvania
G.F.Gebhart,PhD(Retired)
Professor(emeritus) DepartmentofPharmacology
CarverCollegeofMedicine UniversityofIowa IowaCity,Iowa
ArthurG.Lipman†,PharmD
ProfessorEmeritus Pharmacotherapy
UniversityofUtahSchoolofMedicine
AdjunctProfessorofAnesthesiologyandDirectorofClinical Pharmacology
PainManagement UniversityofUtah SaltLakeCity,Utah
TimothyJ.Ness,MD,PhD
SimonGelmanEndowedProfessorofAnesthesiology DepartmentofAnesthesiologyandPerioperativeMedicine UniversityofAlabamaatBirmingham Birmingham,Alabama
JamesP.Rathmell,MD
Chair,DepartmentofAnesthesiology,PerioperativeandPainMedicine BrighamandWomen’sHospital
LeroyD.VandamProfessorofAnaesthesia,HarvardMedicalSchool
Boston,Massachusetts
StevenH.Richeimer,MD ProfessorofAnesthesiologyandPsychiatry Chief,DivisionofPainMedicine DepartmentofAnesthesiology
KeckSchoolofMedicine UniversityofSouthernCalifornia LosAngeles,California
VirtajSingh,MD ClinicalAssistantProfessor DepartmentofRehabilitation UniversityofWashington MedicalDirector
SeattleSpineandSportsMedicine
Seattle,Washington
MarkS.Wallace,MD ProfessorofClinicalAnesthesiology Chair,DivisionofPainMedicine DepartmentofAnesthesiology UniversityofCaliforniaSanDiego LaJolla,California
ChristopherL.Wu,MD ClinicalProfessorofAnesthesiology DepartmentofAnesthesiology
TheHospitalforSpecialSurgery,WeillCornellMedicalCollege
NewYork,NewYork
†Deceased
ContributingAuthors
AlaaAbd-ElSayed,MD
AssistantProfessor/MedicalDirector
UniversityofWisconsin-Madison
Madison,Wisconsin
RogerJ.Allen,PhD,PT
DistinguishedProfessor
SchoolofPhysicalTherapy
NeuroscienceProgram
UniversityofPugetSound
Tacoma,Washington
KevinN.Alschuler,PhD
AssociateProfessor
DepartmentofRehabilitationMedicine
UniversityofWashingtonSchoolofMedicine
RehabilitationPsychologist
UWMedicineMultipleSclerosisCenter
UniversityofWashingtonMedicalCenter
Seattle,Washington
DavidArcella,MD PrivatePractice
TridentPainCenter
Charleston,SouthCarolina
CharlesE.Argoff,MD
ProfessorofNeurology
AlbanyMedicalCollege
Director,ComprehensivePainCenterandPainManagementFellowship
AlbanyMedicalCenter
Albany,NewYork
PaulM.Arnstein,PhD,RN,FAAN
AdjunctAssociateProfessor
Nursing
MGHInstituteforHealthProfessions
ClinicalNurseSpecialistforPainRelief
InstituteforPatientCare
MassachusettsGeneralHospital
Boston,Massachusetts
DesireeAzizoddin,PsyD
PainPsychologyFellow
DepartmentofAnesthesiology,PerioperativeandPainMedicine StanfordUniversity PaloAlto,California
MiroslavBackonja,MD
ClinicalProfessor
Neurology
UniversityofWashington Seattle,Washington
EmeritusProfessor
DepartmentofNeurology UniversityofWisconsin
Madison,Wisconsin
MatthewJ.Bair,MD,MS
AssociateProfessorofMedicine
Medicine
IndianaUniversitySchoolofMedicine
CoreInvestigator
CenterforHealthInformationandCommunication
RondebushVAMedicalCenter
Indianapolis,Indiana
ZahidH.Bajwa,MD,FAHS
Director,BostonHeadacheInstitute
Director,ClinicalResearch,BostonPainCareCenter
Waltham,Massachusetts
TuftsUniversitySchoolofMedicine
Boston,Massachusetts
SamirK.Ballas,MD,FACP,FASCP,DABPM,FAAPM EmeritusProfessorofMedicineandPediatrics
DepartmentofMedicine,CardezaFoundationforHematologicResearch
ThomasJeffersonUniversity HonoraryStaffMember
Medicine,DivisionofHematology
SidneyKimmelMedicalCollege
Philadelphia,Pennsylvania
AndrewBaranowski,BScHons,MBBS,FRCA,MD,FFPMRCA HonorarySeniorLecturer
DepartmentofPainMedicine
UniversityCollegeLondon
Consultant
PainMedicine
UniversityCollegeLondonHospitals
London,UnitedKingdom
AndreiBarasch,DMD,MDSc AssociateProfessor Medicine
WeillCornellMedicalCollege
Attending
Medicine
NewYorkPresbyterianHospital
NewYork,NewYork
DavidBarnard,PhD,JD
RetiredMilesJ.EdwardsChairinProfessionalismandComfortCare CenterforEthicsinHealthCare
OregonHealth&ScienceUniversity Portland,Oregon
KellyBarth,DO AssociateProfessor
DepartmentofPsychiatryandBehavioralSciences MedicalUniversityofSouthCarolina Charleston,SouthCarolina
WilliamC.Becker,MD AssociateProfessor
DepartmentofInternalMedicine YaleSchoolofMedicine
NewHaven,Connecticut
SharonaBen-Haim,MD AssistantProfessor DepartmentofNeurosurgery UniversityofCalifornia,SanDiego SanDiego,California
CharlesBerde,MD,PhD Professor Anesthesia HarvardMedicalSchool
SaraPageMayoChairandChief,DivisionofPainMedicine Anesthesiology,CriticalCareandPainMedicine
BostonChildren’sHospital Boston,Massachusetts
SarahK.Bick,MD
Resident
DepartmentofNeurosurgery
MassachusettsGeneralHospital
Boston,Massachusetts
KlausBielefeldt,MD,PhD
ProfessorofMedicine
Medicine
UniversityofUtah
SectionChief,Gastroenterology
Medicine
GeorgeE.WahlenVAMC
SaltLakeCity,Utah
NikolaiBogduk,BSc(Med),MB,BS,MD,PhD,DSc,MMed,FAFRM, FFPM(ANZCA)
EmeritusProfessorofPainMedicine
TheUniversityofNewcastle
Newcastle,NewSouthWales,Australia
ChristinaEliseBokat,MD
AssistantProfessor
Anesthesiology
UniversityofUtah
SaltLakeCity,Utah
MichaelM.Bottros,MD
AssociateProfessor
DepartmentofAnesthesiology,DivisionofPainMedicine
WashingtonUniversitySchoolofMedicine
St.Louis,Missouri
GaryJ.Brenner,MD,PhD
AssociateProfessor
DepartmentofAnesthesia,CriticalCareandPainMedicine
HarvardMedicalSchool
Director,MassachusettsGeneralHospitalPainMedicineFellowship DepartmentofAnesthesia,CriticalCareandPainMedicine MassachusettsGeneralHospital Boston,Massachusetts
ShaneE.Brogan,MB,BCH DirectorofPainMedicine Anesthesiology
HuntsmanCancerHospital SaltLakeCity,Utah
ChadBrummett,MD
AssociateProfessorofAnesthesiology Director,ClinicalAnesthesiaResearch UniversityofMichigan AnnArbor,Michigan
KellyA.Bruno,MD PainMedicineFellow
DepartmentofAnesthesiologyandPainMedicine UniversityofCalifornia,SanDiego SanDiego,California
ThomasN.Bryce,MD Professor
RehabilitationMedicine
IcahnSchoolofMedicine
AttendingPhysician
RehabilitationMedicine
MountSinaiHospital NewYork,NewYork
AsokumarBuvanendran,MD Professor,DepartmentofAnesthesiology
WilliamGottschalk,EndowedChairofAnesthesiology ViceChairResearchandDirectorofOrthopedicAnesthesia
RushUniversityMedicalCenter
Chicago,Illinois
JacquelineCasillas,MD,MSHS Professor
PediatricsDivisionofHematology-Oncology UniversityofCalifornia,LosAngeles LosAngeles,California
MedicalDirector
PediatricHematology-Oncology
MillerChildren’sHospital LongBeach,California
AusimChaghtai,MD NeurologyResident
AlbanyMedicalCenter Albany,NewYork
WilsonJ.Chang,MD,MPH
PainSpecialist
PainServices
SwedishMedicalCenter Seattle,Washington
C.RichardChapman,PhD ProfessorEmeritus
PainResearchCenter DepartmentofAnesthesiology UniversityofUtah SaltLakeCity,Utah
MartinD.Cheatle,PhD AssociateProfessor DepartmentofPsychiatry
PerelmanSchoolofMedicine,UniversityofPennsylvania Philadelphia,Pennsylvania
SrinivasChiravuri,MD
ClinicalAssociateProfessor
DepartmentofAnesthesiology
UniversityofMichiganMedicalSchool
AnnArbor,Michigan
RogerChou,MD Professor
DepartmentofMedicalInformaticsandClinicalEpidemiology, DepartmentofMedicine
OregonHealth&ScienceUniversity Portland,Oregon
ThomasTaiChung,MD
ClinicalAssistantProfessor
PhysicalMedicineandRehabilitation UniversityofWashingtonSchoolofMedicine Staff
PhysicalMedicineandRehabilitation
SwedishMedicalCenter Seattle,Washington
MichaelR.Clark,MD,MPH,MBA
Chair,DepartmentofPsychiatryandBehavioralHealth InovaHealthSystem FallsChurch,Virginia
DanielJ.Clauw,MD Professor
DepartmentofAnesthesiology,Medicine(Rheumatology),andPsychiatry UniversityofMichigan Director
ChronicPainandFatigueResearchCenter,DepartmentofAnesthesiology
MichiganMedicine
AnnArbor,Michigan
JamesF.Cleary,MD,FRACP,FAChPM Professor
Medicine
UniversityofWisconsinSchoolofMedicineandPublicHealth Madison,Wisconsin
RichardF.CodyJr.,MD NeuroradiologyFellow DepartmentofRadiology
UniversityofWashingtonSchoolofMedicine/HarborviewMedicalCenter Seattle,Washington
PeggyCompton,RN,PhD,FAAN AssociateProfessor
SchoolofNursing UniversityofPennsylvania Philadelphia,Pennsylvania
DavidS.Craig,PharmD
PharmacistLead,SupportiveCareMedicineandAcutePain DepartmentofPharmacy
MoffittCancerCenterandResearchInstitute Tampa,Florida
LaraWileyCrock,MD,PhD ResearchandClinicalFellow DepartmentofAnesthesiology
WashingtonUniversitySchoolofMedicine St.Louis,Missouri
TaylorCrouch,PhD Instructor
DepartmentofPsychiatryandBehavioralSciences
MedicalUniversityofSouthCarolina Charleston,SouthCarolina
MicheleCuratolo,MD,PhD
ProfessorofAnesthesiologyandPainMedicine
EndowedProfessorinMedicalEducationandResearch DepartmentofAnesthesiology&PainMedicine UniversityofWashington
Seattle,Washington
MelissaA.Day,PhD
NHMRCEarlyCareerFellow
SchoolofPsychology
TheUniversityofQueensland Brisbane,Australia
JenniferJ.DeBerry,PhD
AssistantProfessor
Anesthesiology PerioperativeMedicine
UniversityofAlabamaatBirmingham Birmingham,Alabama
RichardA.Deyo,MD,MPH
Professor
FamilyMedicineandInternalMedicine
OregonHealth&ScienceUniversity Portland,Oregon
JanDommerholt,PT,DPT,DAIPM
AssociateProfessor Fisioterapia
UniversidadCEUCardenalHerrera
Valencia,Spain
President/ChiefExecutiveOfficer
BethesdaPhysiocareInc
Bethesda,Maryland
RobertH.Dworkin,PhD
ProfessorofAnesthesiology,Neurology,andPsychiatry DepartmentofAnesthesiology
UniversityofRochesterSchoolofMedicineandDentistry Rochester,NewYork
RobertEdwards,PhD,MSPH
AssociateProfessor
Anesthesiology
HarvardSchoolofMedicine
Psychologist
Anesthesiology
BrighamandWomen’sHospital Boston,Massachusetts
ElonEisenberg,MD ProfessorofNeurologyandPainMedicine
RappaportFacultyofMedicine
Technion IsraelInstituteofTechnology
Head,PainResearchUnit
InstituteofPainMedicine
RambamHealthCareCampus
Haifa,Israel
AndrewJ.Engel,MD
AffordablePainManagement Chicago,Illinois
JoyceM.Engel,PhD,OT Professor
OccupationalScienceandTechnology
CollegeofHealthSciences
UniversityofWisconsin-Milwaukee Milwaukee,Wisconsin
JoelBrianEpstein,DMD,MSD Professor
DepartmentofSurgery
Cedars-SinaiHealthSystem
LosAngeles,California
MedicalDirector,Dentistry DepartmentofSurgery
CityofHopeNationalMedicalCenter Duarte,California
EmadN.Eskandar,MD Professor DepartmentofNeurosurgery
MassachusettsGeneralHospital HarvardMedicalSchool Boston,Massachusetts
SvetlanaFaktorovich,MD ClinicalNeurophysiologyFellow DepartmentofNeurology IcahnSchoolofMedicineatMountSinai NewYork,NewYork
RonnieFass,MD ProfessorofMedicine Medicine
CaseWesternReserveUniversity MedicalDirector,DigestiveHealthCenter Medicine MetroHealthMedicalCenter Cleveland,Ohio
RogerB.Fillingim,PhD DistinguishedProfessor
PainResearchandInterventionCenterofExcellence UniversityofFlorida Gainesville,Florida
EzekielFink,MD TripleBoardCertifiedinNeurology,PainManagement,andBrainInjury
Medicine
MedicalDirectorofPainManagement
HoustonMethodistHospital
Houston,Texas
AssistantClinicalProfessor
DavidGeffenSchoolofMedicineatUCLA
LosAngeles,California
NannaBrixFinnerup,MD,Phd Professor
DepartmentofClinicalMedicine,DanishPainResearchCenter AarhusUniversity Aarhus,Denmark
ScottM.Fishman,MD
FullertonEndowedChairofPainMedicine
Chief,DivisionofPainMedicineandProfessorofAnesthesiology
Director,CenterforAdvancingPainRelief
DepartmentofAnesthesiologyandPainMedicine UniversityofCalifornia,DavisSchoolofMedicine Sacramento,California
DermotFitzgibbon,MB,BCh
Professor
DepartmentofAnesthesiologyandPainMedicine UniversityofWashingtonSchoolofMedicine
MedicalDirector,PainandAnesthesiaServices
SeattleCancerCareAlliance Seattle,Washington
GregoryC.Gardner,MD,FACP
Gilliland-HendersonProfessorofMedicine DivisionofRheumatology
AdjunctProfessorofOrthopedicsandRehabilitationMedicine UniversityofWashington Seattle,Washington
RobertJ.Gatchel,PhD,ABPP
DistinguishedProfessorandDirector,CenterofExcellencefortheStudy ofHealthandChronicIllnesses,NancyP.andJohnG.PensonEndowed ProfessorofClinicalHealthPsychology
DepartmentofPsychology,CollegeofScience
UniversityofTexasatArlington Arlington,Texas
G.F.Gebhart,PhD(Retired)
Professor(emeritus)
DepartmentofPharmacology
CarverCollegeofMedicine
UniversityofIowa IowaCity,Iowa
YoussefGhabrial,MB,ChB,MOrth,DS,FRCS,FRACS ProfessorofOrthopedicSurgery
SchoolofMedicineandPublicHealth FacultyofHealthandMedicine
TheUniversityofNewcastle
StaffSpecialist
DepartmentofOrthopedicSurgery
JohnHunterHospital
Newcastle,NewSouthWales,Australia
KimberlyVarneyGill,PharmD,BCPS,BCCCP
ClinicalPharmacySpecialist,CriticalCare,MedicalRespiratoryICU, VCUMedicalCenter
AssociateClinicalProfessorofPharmacy,VCUSchoolofPharmacy
AssistantClinicalProfessorofMedicine,VCUDepartmentofInternal Medicine
Richmond,Virginia
ChristopherGilligan,MD,MBA
AssistantProfessor
Anesthesia
HarvardMedicalSchool
Chief,DivisionofPainMedicine
DepartmentofAnesthesiology,PerioperativeandPainMedicine BrighamandWomen’sHospital
Boston,Massachusetts
AaronM.Gilson,MS,MSSW,PhD
ResearchProgramManager/SeniorScientist CarboneCancerCenter
UniversityofWisconsinSchoolofMedicineandPublicHealth Madison,Wisconsin
LeeGlass,MD,JD AssociateMedicalDirector
DepartmentofLaborandIndustries Olympia,Washington
PeterJ.Goadsby,MD,PhD,DSc,FRACP,FRCP,FMedSci ProfessorofNeurology InstituteofPsychiatry,PsychologyandNeuroscience King’sCollegeLondon
London,UnitedKingdom
LayneA.Goble,PhD
ClinicalPsychologist
Anesthesia CharlestonVAMedicalCenter
AssociateProfessor
AnesthesiaandPerioperativeMedicine MedicalUniversityofSouthCarolina
Charleston,SouthCarolina
MichaelS.Gold,PhD ProfessorofNeurobiology
DepartmentofNeurobiology
UniversityofPittsburghSchoolofMedicine
Pittsburgh,Pennsylvania
DouglasL.Gourlay,MD,MSc,FRCP(C),DFASAM EducationalConsultant Ontario,Canada
BenjaminL.Grannan,MD ResidentPhysician
DepartmentofNeurosurgery
MassachusettsGeneralHospital Boston,Massachusetts
RobertGriffin,MD,PhD
ClinicalAssistantProfessor
Anesthesiology
WeillCornellMedicalCollege
AssistantAttendingAnesthesiologist
Anesthesiology,CriticalCare,andPainManagement HospitalforSpecialSurgery
NewYork,NewYork
NarasimhaR.Gundamraj,MD AssistantProfessor CollegeofHumanMedicine
MichiganStateUniversity Physician
PainManagementCenter
SparrowHospital
EastLansing,Michigan
MuhamedHadzipasic,MD,PhD ResidentPhysician
DepartmentofNeurosurgery
MassachusettsGeneralHospital
Boston,Massachusetts
NeilA.Hagen,MD,FRCPC
ProfessorEmeritus
DepartmentsofOncology,ClinicalNeurosciencesandMedicine
CummingSchoolofMedicine,UniversityofCalgary Calgary,Canada
EmilyHagn,MD
AssistantProfessor
DepartmentofAnesthesiology
UniversityofUtah
SaltLakeCity,Utah
MarieN.Hanna,MD,MEHP
AssociateProfessor,ChiefDivisionofRegionalAnesthesiaandAcute PainManagement
DeparmentAnesthesiaandCriticalCareMedicine
JohnsHopkinsUniversity Baltimore,Maryland
RobertNormanHarden,MD Professor
RehabilitationInstituteofChicago NorthwesternUniversity Chicago,Illinois
SimonHaroutounian,PhD,MScPharm
AssistantProfessor
DepartmentofAnesthesiology
WashingtonUniversitySchoolofMedicine
St.Louis,Missouri
MichaelHauck,MD,PhD
ResearchFellow
InstituteofPathophysiologyandNeurophysiology
UniversityMedicalCenterHamburg-Eppendorf AttendingPhysician
DepartmentofNeurology
UniversityMedicalCenterHamburg-Eppendorf Hamburg,Germany
HowardA.Heit,MD,FACP,FASAM EducationalConsultant
Reston,Virginia
JeanneHernandez,PhD,MSPH
DirectorofBehavioralMedicine,AssistantProfessor(Retired) DepartmentofAnesthesiology SchoolofMedicine,UniversityofNorthCarolinaChapelHill ChapelHill,NorthCarolina
KeelaHerr,PhD,RN,AGSF,FGSA,FAAN ProfessorandAssociateDeanforFaculty CollegeofNursing UniversityofIowa IowaCity,Iowa
AnitaH.Hickey,MD PainManagementPhysician NavalMedicalCenterSanDiego SanDiego,California
JosephGregoryHobelmann,MD,MPH AdjunctFaculty DepartmentofPsychiatryandBehavioralSciences JohnsHopkinsUniversity Baltimore,Maryland ChiefMedicalOfficer
AshleyAddictionTreatment HavredeGrace,Maryland
PamelaJ.Hughes,DDS
AssociateProfessorandDepartmentChair OralandMaxillofacialSurgery
OregonHealthandScienceUniversity
Portland,Oregon
RobertW.Hurley,MD,PhD
Professor
SectionChiefofPainMedicine
AnesthesiologyandPublicHealthSciences
WakeForestUniversity
ExecutiveDirector
PainServiceLine
WakeForestBaptistHealth
Winston-Salem,NorthCarolina
S.AsraHusain,JD,MA
LegalandPolicyAnalyst
UWCarboneCancerCenter
Pain&PolicyStudiesGroup
UniversityofWisconsin
Madison,Wisconsin
CharlesE.Inturrisi,PhD
Professor
DepartmentofPharmacology
WeillCornellMedicine
NewYork,NewYork
GordonIrving,MB,BS,MSc(Med),MMED,FFA(SA)
Attending
SwedishPainServices
SwedishMedicalCenter
Seattle,Washington
RobertN.Jamison,PhD Professor
DepartmentsofAnesthesiaandPsychiatry
HarvardMedicalSchool
Boston,Massachusetts
PainManagementCenter
BrighamandWomen’sHospital
ChestnutHill,Massachusetts
NoraJanjan,MD,MPSA,MBA
SeniorFellow
NationalCenterforPolicyAnalysis Dallas,Texas
MarkP.Jensen,PhD
ProfessorandViceChairforResearch
RehabilitationMedicine
UniversityofWashington Seattle,Washington
KajJohansen,MD,PhD
ClinicalProfessorofSurgery DepartmentofSurgery
UniversityofWashingtonSchoolofMedicine
StaffVascularSurgeon DepartmentofSurgery
SwedishMedicalCenter
Seattle,Washington
AnandB.Joshi,MD,MHA
AssistantProfessor
OrthopedicSurgery
DukeUniversitySchoolofMedicine
AssistantProfessor
OrthopedicSurgery
DukeHealth
Durham,NorthCarolina
JamesD.Kang,MD Chairman
OrthopedicSurgery
HarvardMedicalSchool
BrighamandWomen’sHospital
Boston,Massachusetts
RoyL.Kao,MD
AssistantClinicalProfessor
Pediatrics
DavidGeffenSchoolofMedicineatUCLA
LosAngeles,California
PediatricHematologist/Oncologist
MillerChildren’sandWomen’sHospital
LongBeach,California
MichaelL.Kent,MD
AssistantProfessor
DepartmentofAnesthesiology
UniformedServicesUniversity
StaffAnesthesiologist
DepartmentofAnesthesiology
WalterReedNationalMilitaryMedicalCenter
Bethesda,Maryland
WadeKing,MB,BS,MMedSc,MMed(PainMgt.),GDMuscMed, FAFMM
PainPhysician
MayoMultidisciplinaryPainClinic
MayoPrivateHospital
Taree,NewSouthWales,Australia
NancyD.Kishino,OTR/L,CVE Director
WestCoastSpineRestorationCenter Riverside,California
ClaudiaKohner,PhD
LicensedClinicalPsychologist