Case Study
Decibel Therapeutics Maximizes Every Data Point with elluminate
Business Challenge: Proactively manage and monitor data across a growing portfolio As a biotechnology company that specializes in clinical trials for rare diseases, Decibel Therapeutics needed to make the most of their many data sources. Like many emerging biotech companies experiencing rapid growth, they were contending with resource constraints and aggressive timelines. Decibel had to initially establish a first trial to provide proof of concept data. In order to maximize the clinical data from the initial trial and to make sure it was available for comparison and analyses, the company wanted to implement a data-centric approach to the trial design. They had to ensure the data was robust and that they would have the ability to integrate it with future data sources. The development of an effective data pipeline early on meant that future trials would benefit from quicker trial design and activation. In general, urgency is typically needed in initial trials to secure funds, which rarely allows for data review pipelines to be built out properly and efficiently. Decibel knew that they needed a centralized platform to provide an adaptable data review pipeline that could integrate multiple and new data sources as the trial evolved. They also wanted a platform that could standardize all data sources to make data review more efficient. To optimize their data sources, especially early in the trial, Decibel required a scalable and cost-effective platform that could be rapidly implemented by a small team.
Scaling development operations by investing in elluminate,® a centralized clinical data platform Decibel found that eClinical Solutions’ elluminate clinical data platform was an excellent fit for their current requirements and for the future. Implementing the platform was seamless, even for non-technical members of their team. Despite having diverse data sources—including animal studies and natural progression studies—the elluminate Mapper product was able to aggregate and standardize all ingested data. With elluminate, all available data is stored in a centralized location. If any data points are missing, or have been entered incorrectly, Decibel can be instantly notified through alerts. This allows for a more efficient data review process.
■ Headquartered in Boston ■ Focused on discovering and developing transformative treatments to restore and improve hearing and balance.
Success highlights ■ Faster data access ■ CRO oversight ■ Ability to scale