Design Samples

5.5 x 5.5 Tri-fold Brochure

DolCas Biotech, LLC.

DolCas Biotech was established in 2007 as an extension of its founding corporation, Orcas Naturals. The goal being to establish and grow the then, budding interest of branded nutraceuticals. We understood that marketing branded ingredients required a more attentive focus on our customers and a more thorough understanding of the marketplace.

Bergamot and Cynara leaf Extract

To continue our vision for true transparency and quality through vertical integration, DolCas established, in 2017, its own manufacturing arm, DolCas Botanosys in Bikaner, India.

The company’s most recent evolution (2019) includes its incorporation into the joint-venture entity, Dolcas Tenshi Bioceuticals, Inc. The JV partners Tenshi’s innovation procurement acumen with Dolcas’ commercialization strategy and expertise to develop and launch globally, novel, clinically supported branded ingredients, supplying customers with unique market and product development opportunities.

9 Lenel Road Landing NJ 07850 info@DolCas-Biotech.com 1-888-806-7227 is a registered trademark of HEAD srl, exclusively licensed to DolCas Biotech, LLC. Statements in this brochure have not been evaluated by the Food and Drug Administration.

This product is not intended to diagnose, treat, cure or prevent any disease.

Clinically Proven Benefits The first branded botanical ingredient of its kind to establish a proven liver support mechanism in populations that have accumulated excess liver fat. Overly excessive fat in the liver, generally brought on by poor lifestyle choices, is metabolically active and is believed to set the stage for chronic diseases of cardio-metabolic origin. Bergacyn’s affinity to the liver and support of healthy immune and inflammatory function, provides antioxidant, lipid and glucose metabolism support, helping to unburden an often overlooked organ.

Liver Fat

The Calabrian-exclusive Bergamot citrus fruit and wild-variety Italian Cynara cardunculus leaf extracts are blended in a patented process. In a clinical trial of overweight subjects, the Bergacyn® blend demonstrated highly efficacious results, at conveniently low doses. Bergacyn® intake significantly reduced liver fat, LDL-c, BMI and weight, demonstrating support of healthy liver function.

Design • 102 subjects • 12-wk DBPCR study: Italy

Results •

9% CAP score (OT group; n=87) (-21.3 dB/m > placebo (p=0.02)

•

9.6 lb. total weight loss (~ 4 lb. > placebo; p=0.004)

•

Inflammatory markers (IL-6, TNF-α, PGE2; p<0.0001)

•

7.8% cLDL Bergacyn® ONLY (116 to 107 mg/dl; p=0.02)

5.5 x 5.5 Tri-fold Brochure

Dolcas Tenshi Bioceuticals (DTB)

is a joint venture company between Tenshi, a technology focused specialty pharmaceutical company, and DolCas,

a leading US-based, research-driven marketing and

distribution firm, specializing in branded nutraceutical ingredients. DTB will focus exclusively on the research,

development, and commercialization of novel nutraceutical products for key global markets. The new company brings together the diverse capabilities of the two

established partners, both with many years of experience in building and scaling innovative businesses.

9 Lenel Road Landing NJ 07850 info@DolCas-Biotech.com 1-888-806-7227 is a trademark of DT Bioceuticals, Inc. Statements in this brochure have not been evaluated by the Food and Drug Administration.

This product is not intended to diagnose, treat, cure or prevent any disease.

Staying competitive in a crowded market means standing out.

Distinguish yourself and dominate the complex curcumin market with the next-GENeration of curcumin: Curcugen™ is a clean, highly concentrated, clinically-studied curcumin ingredient, boasting a 98.5% turmeric base, and a very high, 50% curcuminoid concentration. Curcugen™ begins its novel development with the turmeric oleoresin, a base ingredient with a more comprehensive profile of turmeric bioactives than the industry’s standard of starting material, 95% curcuminoids. The oleoresin is the native matrix where turmeric’s curcuminoids, essential oils and resins are found, and its longstanding use as a food flavor and color ingredient supports its functional and preferential use in Curcugen™.

The Curcugen™ oleoresin is optimized by the patent-pending SELFD™ platform technology. In this unique format, the food-state ratio of curcuminoids is maintained, its beneficial essential oils are retained, and otherwise discarded resins are made functional, by prioritizing those that are more polar.

The ‘functional’ resins in Curcugen™ add significant value to the ingredient, minimizing curcumin’s need for non-turmeric bioenhancers or nanotechnology. This innovative brand enhances curcumin’s bioavailability by 30-times*, delivers a self-dispersion profile for easy and versatile delivery options, and provides a sustained release mechanism for efficient dosing.

CLINICALLY PROVEN

The ‘Next Generation’ Difference 30X enhanced bioavailability 98.5% turmeric-based Oleoresin sourced 50% curcuminoids ‘Food-state’ curcuminoid ratios Retained turmeric essential oils Self-dispersing property Sustained released mechanism Versatile delivery options* Clinically proven

*e.g. Traditional Formats • Powdered Drinks • Oral Dispersible • Hard Candy • Ready-To-Drink • Effervescent • Gummies • Functional Foods

Curcugen™ is posited to increase the surface area of otherwise clustered curcumin molecules, increasing their interaction with water and the gut lining, thereby enhancing their absorption. The optimized resins, otherwise known as P-resins are thought to release the curcumins slowly over time, evidenced by its sustained release.*

*As evidenced by bioavailability study results and properties in water.

5.5 x 5.5 Tri-fold Brochure

DolCas Biotech, LLC.

DolCas Biotech was established in 2007 as an extension of its founding corporation, Orcas Naturals. The goal being to establish and grow the then, budding interest of branded nutraceuticals. We understood that marketing branded ingredients required a more attentive focus on our customers and a more thorough understanding of the marketplace.

The Goodness of Olives, Enhanced

To continue our vision for true transparency and quality through vertical integration, DolCas established, in 2017, its own manufacturing arm, DolCas Botanosys in Bikaner, India.

The company’s most recent evolution (2019) includes its incorporation into the joint-venture entity, Dolcas Tenshi Bioceuticals, Inc. The JV partners Tenshi’s innovation procurement acumen with Dolcas’ commercialization strategy and expertise to develop and launch globally, novel, clinically supported branded ingredients, supplying customers with unique market and product development opportunities.

9 Lenel Road Landing NJ 07850 info@DolCas-Biotech.com 1-888-806-7227 is a trademark of DolCas Biotech, LLC. Statements in this brochure have not been evaluated by the Food and Drug Administration.

This product is not intended to diagnose, treat, cure or prevent any disease.

Clinically Proven Benefits

A USDA and EU organic, Kosher- and Halal-certified, 100% solvent-free extract of rich polyphenols from whole, fresh olive fruits and leaves. Unlike other olive extracts, TruOliv™ is a wholefood complex delivering a potent polyphenol profile exclusive of its unique, desert-growing conditions and 4-generations of cultivation expertise.

TruOliv™ stands out from its competitors as it is not sourced from the ‘waste-water’ byproducts of olive oil production, nor chemical hydrolysis or solvent processes, which tend to favor high concentrations of single polyphenols over the research-proven benefits of a synergistic profile. At 10% polyphenols (total), ~ 2% hydroxytyrosol, 6% oleuropein, and measurable amounts of synergistic phenols (i.e. oleacin, olecanthal, luteolin, etc.), TruOliv™ is truly unmatched in quality and clinical potential.

Joint Health Support

Cardiometabolic Health Support

Design

Design

• 90 RA subjects; avg. 55 y.o.

• 8-wk DBPCR study; Morocco

• 80 NIDDM subjects; avg. 55 y.o.

• 14-wk DBPCR study; Morocco

Results

Results

•

1.23 DAS-28 score (p<0001)

• •

•

•

1.3% HbA1C (from 7.79; p<0.0001)

35% pain intensity

•

5.1 mg/dL HDL (p=0.007)

Inflammatory markers (IL-6, TNF-α, PGE2; p<0.0001)

•

1.4 HOMA-IR (p<0.0002)

•

44.4 Triglycerides (p <0.0001)

1.37 mg/L hs-CRP

This art was part of Pure Energy’s Marketing

NO

108

NORMANDY BEACH

PRESENTED BY

Eliminate Green Water with

BENEFICIAL BACTERIA

What is Beneficial Bacteria?

Beneficial Bacteria are microscopic organisms that naturally grow in ponds. These bacteria fight green-water algae by competing with the algae for one of its favorite foods: nitrites (a byproduct of ammonia breaking down in the pond).

Bacteria colonize in your biofilter and on rocks and gravel, but you should add supplemental doses at least once a week to keep the population healthy. Keeping up with these water treatments will ensure you have crystal-clear water and happy, healthy fish -without the use of algaecides.

DOSING INSTRUCTIONS STEP 1: DETERMINE POND SIZE My pond is approximately ________ gallons.

Length (ft.) x Width (ft.) x Avg. Depth (ft.) x 7.48

STEP 2: CALCULATE DOSING I need to use ___ pumps of bacteria when I treat the pond.

Add bacteria at a rate of one pump per 100 gallons of water if using the 8 oz., 16 oz. or 32 oz. bottle. If using the gallon container, add one pump per 600 gallons of water. Too much bacteria will not harm your pond life so always round up.

STEP 3: DETERMINE FREQUENCY If you have clear water: • Treat 1 x per week for maintenance.

If you have green water: • Treat 3 x per week for two weeks • Treat 2 x per week for the next two weeks • Treat 1 x per week for maintenance year round, switching to a Cold Water formula or Arctic Blend in late fall.

Worried about forgetting a treatment? Take the guesswork out of pond care with an Automatic Dosing System.

GOOD THINGS TAKE TIME! Beneficial Bacteria will not make your water instantly clear. Give it a few weeks to colonize and do its work. If green water persists, ask us about upgrading your filtration.

And remember: Keep up with weekly bacteria doses, even after the water clears. Stopping treatments will likely turn your water green again bringing you right back where you started.

908.329.6176 • 2656 Route 57, Stewartsville, NJ 08886

Come Visit That Pond Place, the New Home of Full Service Aquatics!

•Aquatic Plants •Koi and Goldfish •Tadpoles and Snails •Pond Lighting •Water Treatments •Fish Food •Pumps •Aerators •Algae Control •Gift Shop •Garden Decor •Filters •Nets •So Much More!

ALL POND SERVICES

New Construction | Renovation | Cleaning | Maintenance | Repairs Check out our great selection of hardy and tropical water lilies, lotus, marginal and floating aquatics plants, colorful koi and goldfish.

Welcome All Full Service Aquatics Clients!

Visit our website and Facebook page for the most up-to-date store hours. Seasonal hours apply.

2656 State Route 57 Stewartsville, NJ 08886 | 908-329-6176 | www.ThatPondPlace.com

F R E E

Your choice of one floating plant (hyacinth or lettuce), or 1 comet goldfish, or sample size premium quality fish food.

While supplies last with this coupon.

Check out

www.FullServiceAquatics.com

Pond construction and service for all your pondʼs needs!

Project financing available!!

2656 State Route 57 Stewartsville, NJ 08886 908-329-6176 | www.ThatPondPlace.com

10% O F F On purchase of up to $300.

Discount not to exceed $30, with this coupon.