CHILDREN'S HOSPITAL of PITTSBURGH FOUNDATION

This is the Hospital that Katie Needs.

DEDICATED TO THE PEOPLE WHO CARE FOR CHILDREN’S

Stepinto

the world of a child who is very ill.

She’s afraid because she’s in a strange place. She doesn’t know what will happen next.

Imagine how this child’s parents feel. They are consumed with worry and stress because of what the future may hold.

Think of the doctors and nurses called to help this child. They’re trained to respond quickly and skillfully, but crowded conditions challenge their every move.

This is the world of the current Children’s Hospital of Pittsburgh. Yet, despite cramped patient rooms, a teeming Emergency Department, and limited research space, this hospital continues to offer world-class care, and achieve patient outcomes that are among the best anywhere.

We are driven by this mission. Our vision of the future is simple. We will raise the bar—not only by enabling our brilliant clinicians and researchers to practice in an outstanding facility but by making every child who comes through our doors feel more at ease, and every family more reassured.

But if we are to achieve our goals, there are needs that cannot be ignored. You can help expand our facilities and our horizons. With your generosity, Children’s Hospital of Pittsburgh will become one of the top five pediatric healthcare centers in the country—

a hospital that every child needs.

CARING FOR CHILDREN’S

Dear Friends, It has been continually rewarding to play a part in the tremendous work done at Children’s Hospital of Pittsburgh. Children’s has long been a leader in advancing pediatric medicine. In the 1950s, it was Jonas Salk’s miraculous polio vaccine. In the early 1980s, it was the start of the transplantation program that has performed more pediatric organ and tissue transplants than any other center.

Through other pioneering treatments and research, children with cystic fibrosis, cancer, sickle cell disease and heart defects have been able to live longer, fuller lives than anyone ever dreamed possible. And historic progress is being made toward finding the cause and, thereby, a cure for juvenile diabetes.

Our medical capability has grown alongside our commitment to the community. Families of the Pittsburgh region know that Children’s will never turn away a child in need.

This hospital has cared for generations of our children.

As Children’s now faces several large and pressing issues— steadily increasing demand for care, rapidly outmoded facilities, and the explosive growth of research—we again are fortunate to play a part in helping Children’s take its next big step.

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As you can see on the pages that follow, the new Children’s Hospital of Pittsburgh will fuel excellence on every level.

In addition, the new facilities will be a dynamic engine of growth, adding $100 million annually to the region’s economy and creating more than 1,000 well-paying jobs.

This institution has proven to be a true benefit to our region. Thus the goal of raising $100 million for construction, clinical programs and research is clearly as wise an investment for western Pennsylvania today as it was when Children’s was founded in 1890.

The funds raised in this Capital Campaign will supplement substantial support from UPMC and Highmark, making this the legacy of an entire community.

Please join us in this most rewarding effort, and show that you, too, care for Children’s.

Sincerely,

Thomas G. Bigley, Co-Chair

Edwin F. Scheetz Jr., Co-Chair

Catharine M. Ryan, Incoming Chair

Mary Jo Howard Dively, Esq., Vice Chair

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Since its beginnings, Children’s Hospital of Pittsburgh has depended upon the philanthropic generosity of the region.

This renowned hospital has cared for generations of our children. Now, at this important moment, we must show that we care for Children’s. Your generosity will help shape Children’s Hospital for the next 100 years.

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NITY NITY

THE LEGACY OF AN ENTIRE COMMUNITY

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$100 million Foundation Capital Campaign Goal

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$68.6 million site exploration and purchase Highmark

rchase rchase HH A LANDMARK CAMPUS Site Size Total Square Footage Total Beds Expansion Beds Critical Care Beds Private Rooms Operating Rooms Transport Helipads Emergency Exam Rooms Research Lab Footage Parking Spaces

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10 acres 1.5 million 262 47 79 nn 246 13 2 41 300,000 1,400

Imagine

Technology ranging from wireless networking to reconfigurable floor plans will ensure that Children’s will embrace the future. This will be one of the first paperless, digital pediatric hospitals, where a child’s doctor can view the complete patient chart from anywhere on campus and simultaneously with other caregivers.

the possibilities. In the new Children’s Hospital of Pittsburgh, there will be room to grow and deliver the highest levels of patient care.

For example, in the clinical services building, families are immediately welcomed by clear and simple directional signs, electronic message boards and family gathering areas. A total of 262 beds, virtually all in private rooms, will provide more personalized care in a family-centered environment.

Careful thought has been given to locate units and operations that frequently work together. For example, the orthopaedic outpatient clinic will be adjacent to the X-ray and imaging services. The cardiac intensive care unit will be on the same floor as the catheterization laboratories and the operating rooms.

With nine floors, three parking garages and two helipads, there will be ample room for everyone.

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The new research building, with 300,000 square feet of bright, high-tech lab space, has been expertly designed to encourage collaboration. Conveniently located adjacent to the clinical services building, the research facility includes a 200-seat auditorium with full teleconferencing ability and capacity for 70 researchers and their teams.

This will be one of the first pediatric healthcare institutions to pursue the Leadership in Energy and Environmental Design (LEED) 2.0 standards, joining the wave of new “green” projects that are transforming the Pittsburgh region. In constructing a new campus, Children’s can take into consideration the direct and

indirect effects that buildings have on the health of patients, families and staff. Through the use of nontoxic materials, energy-efficient natural lighting and other building techniques, we can cut our daily operating costs while improving the impact on our internal and external environments.

The new Children’s Hospital will be a tribute to the extraordinary dedication and continual accomplishments of its physicians and staff. But more important, it will be a warm and welcoming place for families—a place where exceptional care will be skillfully delivered in an environment that makes every child feel safe and comfortable.

A WARM WELCOME

Katie Prosser A

P I C T U R E

O F

K

H E A L T H

atie Prosser was diagnosed with a malignant brain tumor at the age of 15 months. Although there seemed little hope for a cure, Katie is the picture of health today, thanks to Children’s Hospital of Pittsburgh. Katie’s doctors followed her surgery with chemotherapy and intensity-modulated radiation therapy—a new protocol that delivers high doses of radiation to the tumor, while minimizing radiation to the healthy brain tissue. Katie was one of the youngest patients ever to be treated with this sophisticated therapy.

Now, at age 5, Katie is tumor-free, and her prognosis is excellent.

“She doesn’t remember being sick,” says Katie’s mother, Valerie Prosser.

“We could not have received better care anywhere.”

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This is the Room that Katie Needs.

Look around

through Katie’s eyes. What makes this place so special?

It feels more like home, rather than a hospital room, with inviting colors and soft fabrics.

involvement is a clear benefit, the crowding can challenge caregivers’ ability to control infection, ensure patient privacy and provide other components of high-quality care.

When Children’s Hospital of Pittsburgh embarked on the development of a new facility, we asked doctors, nurses, parents and also children what they needed in a hospital.

In the new Children’s Hospital of Pittsburgh, nearly every patient room, including those in critical care units, will be private. Patients will have more control over noise, lighting and room temperature, and families will enjoy more options for creating a sense of normalcy.

Their answers inspired us. Bright colors, beds set at age-friendly heights. Sleeping space for parents who want to stay with their child.

Desks, data ports and so much more. Slowly, the vision evolved, meshing the wish lists of patients and their families with those of world-renowned clinicians, nurses and researchers.

Inpatient rooms will have a standardized staff zone, so that caregivers can easily acclimate to the work processes. There will be more flexibility in assigning beds and coordinating the number of caregivers with the needs of patients.

Each year, more than 12,000 patients are admitted to Children’s Hospital of Pittsburgh.

They stay an average of five days in semiprivate rooms designed to hold two patients. But often, concerned parents and guardians stay by the bedside for hours each day. While the family’s

Each 21-bed inpatient unit also will bring caregivers closer to patients, thereby increasing response times and decreasing the possibility of error. With more room for patients, and greater staff efficiency, the new Children’s will rise to meet the needs—and the challenges—of the future.

“

From a distance, we wanted children to say, ‘That’s my building!’ It was important that this new hospital be designed to convey a sense of welcoming—the fact that they have reached an important destination designed just for them.

Upon entering the campus, we wanted all visitors—patients, families and staff—to feel uplifted and hopeful. The new Children’s campus is meant to transform our patients from a state of illness to wellness.

“

ANDREW H. URBACH, MD Assistant Medical Director for Clinical Excellence 12

A ROOM FULL OF COMFORT, CHEER AND KATIE’S BEARS.

David Rogan R E A L

H O P E

D

avid’s story is miraculous. Struck by lightning at a family reunion, David did not respond to CPR. His heartbeat was restored during the ambulance ride to the local hospital, and David was redirected to Children’s Hospital of Pittsburgh. But there were severe complications.

Testing showed profound deafness in both ears, and symptoms of a torn deep membrane.

Otolaryngologist Dr. David Mandell explained the uncertainties of surgery to David’s parents. “That’s one of the things that I find to be very special at Children’s Hospital—we very carefully keep the family in the loop,” he says.

David’s surgery was doubly successful. Not only did his cognitive faculties return, but his hearing was restored as well.

“They’re just amazing at Children’s,” said David’s mother, Jenny.

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This is the Healing Garden that David’s Family Needs.

Everyone

This is a world away from the hospital’s current condition. Today, physical limitations can interfere with care. Because rooms are crowded, families are not always able to provide comfort and encouragement at their child’s bedside. Caregivers must take time to find parents and guardians for consultations or to be present for their children’s procedures.

who is sick needs a hand to hold. But for children like David, the need goes far beyond that.

That’s why, decades ago, Children’s created one of the first family advisory councils in pediatric healthcare. And why, today, we’re building a campus with thoughtful amenities throughout, and four times more space for families than other pediatric centers.

With the realization of the Lawrenceville campus, Children’s will offer private rooms, plus many opportunities for families to gather together or to be alone. To work, learn, eat, play and—ideally—stay strong.

Patients and their families can gather in a 20,000-square-foot Resource Center and Solarium that will serve as the hospital’s “town square,” complete with classrooms, libraries, a business center for working parents, and a chapel for all faiths.

We welcome the family as an integral part of each patient’s healthcare team because we know that they not only provide a valuable link between child and caregivers, they also impart a special brand of support that cannot come from anyone else.

Activity rooms on every inpatient unit will be designated “medical-free zones,” where patients, parents and siblings can go to forget illness for a while. A beautiful, 500-square-foot rooftop Healing Garden will be available with fresh air and flowers in the day and twinkling lights at night.

When we help a family cope with their child’s illness, the family is better able to help us care for their child.

“

Communication is the most important thing we do.

It’s important to listen to what the patient and parents are telling you, and then to pursue data, in part, by asking the right questions. We also try to put ourselves in the shoes of the parents.

We recognize that an emergency room is not where they want to be, but we want their perception of the experience to be as good as it can be.

“

RICHARD A. SALADINO, MD Chief, Pediatric Emergency Medicine

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A HEALING GARDEN TO RESTORE SPIRITS.

Matthew Ricketts F A S T

S A V E

T

he chances of Matthew recovering from near-fatal brain injuries suffered in a car crash were slim. But thanks to the expertise of a multidisciplinary trauma team at Children’s Hospital, the teen’s outcome was good.

The car Matthew was riding in ran up an embankment and flipped over. Matthew’s blood pressure was undetectable, and he was not able to take oxygen into his badly damaged lungs. Matthew was in danger of bleeding to death. With his brain swelling, he slipped into a coma.

Surgeon Edward M. Barksdale Jr., MD, repaired Matthew’s lung, and the brain swelling began to subside. Within a month, Matthew awoke from his coma and quickly recovered. He returned to high school for his senior year and played a starring role on his high school soccer team.

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This is the Care that Matthew Needs.

How

would you feel if your child had a serious head injury and was being rushed to the hospital? You would want the best medical team, the best technology, and the best chance for a positive outcome.

and scientists is the need for more laboratory and clinical space.

Some of the new centers envisioned at Children’s include: Comprehensive Fetal Intervention Center to address congenital problems detected in utero by obstetrician-gynecologists

In 2006, nearly 60,000 children passed through Children’s emergency room, and 1,700 patients were admitted to the Benedum Pediatric Trauma Program. With the busiest pediatric trauma center in the country, the largest pediatric transplantation institute anywhere, and leading centers for the treatment of diabetes, cystic fibrosis and other childhood illnesses, we already enjoy a reputation for outstanding clinical care.

And we are vitally poised for future growth.

Comprehensive Intestinal Care Center that will make possible more successful intestine transplants in very small children Cell Transplantation Center that will treat muscle, bone and organ diseases Pediatric Surgery Center that is state-ofthe-art, with minimally invasive surgical suites and three-dimensional imaging technology

Pediatric Diagnostic Referral Center, with Thanks to new technology, scientific research and a team of forward-thinking physician-scientists, a larger team of “super-diagnosticians” who will address the most complex pediatric problems Children’s Hospital of Pittsburgh is prepared to forge ahead to make caring for children gentler, When the new Children’s is complete, we less invasive and far more effective. will achieve the vision of a pediatric hospital that is—and will remain—one of the very best The only barrier that currently exists to in the country. attracting and retaining world-class physicians

“

Children’s is one of a few hospitals in the country that has united a well-established clinical program with an equally rich research agenda. The collaboration between the hospital and the University of Pittsburgh has been strong for generations. In this environment and with the capacity of a new campus, I can see pediatric surgery forging even closer alliances with areas such as transplantation, robotics and tissue engineering to develop innovative therapies for children.

“

GEORGE K. GITTES, MD Chief, Department of Pediatric Surgery, Surgeon-in-Chief 20

THE BEST POSSIBLE CARE MADE EVEN BETTER.

Jakob Jasin A

N E W

B E G I N N I N G

J

akob Jasin was born with Maple Syrup Urine Disease (MSUD), a metabolic disease that causes amino acids to accumulate in the body. The toxic effect can lead to brain swelling, neurological damage and death.

During his first four years, Jakob’s metabolism was somewhat controlled by an extremely regimented diet free of protein with amino acids. Unlike most kids, Jakob was not able to eat meat or dairy products. He had never tasted ice cream.

Despite his diet, Jakob continued to suffer approximately three metabolic crises a year. Even something as simple as a cold could lead to brain swelling.

The Jasins were led to Children’s Hospital of Pittsburgh, where experts recommended a liver transplant.

Since the successful transplant, Jakob can eat a regular diet, and his amino acid levels have remained normal. His family gained peace of mind, and other children with MSUD gained a new method of cure.

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This is the Research that Jakob Needs.

Let’s put

dramatically improving the lives of young transplant patients, helping them survive longer than before—and with less need than ever for harmful antirejection drugs.

research under a microscope.

Let’s examine the quality and quantity of medical breakthroughs that affect children like Jakob.

By any measure, Children’s Hospital of Pittsburgh stands out as a leader.

They are studying how to prevent allergies, and how to improve outcomes for a wide range of pediatric conditions, from otitis media (middle ear infection) to pediatric cancer.

Because we focus the best scientific minds on some of the most devastating pediatric healthcare problems, Children’s consistently develops new treatments and cures that affect hundreds of thousands of children annually, well beyond the borders of western Pennsylvania.

In spite of extremely limited laboratory space, researchers at Children’s Hospital of Pittsburgh conduct twice the volume of research per square foot than the national average. Expanding research programs have triggered a frequent refrain from productive investigators: “I desperately want to recruit more people, but there is nowhere to put them.”

Right now, scientists at Children’s are working on cures in the next decade for type 1 diabetes, cystic fibrosis, juvenile rheumatoid arthritis and Duchenne muscular dystrophy.

They are developing gene therapies that will Imagine the new levels of research that will keep some of the most delicate premature infants alive and growing normally. They are formulating be possible in the new Children’s—with even more vaccines to prevent common and often deadly dedicated scientists, more laboratory facilities and truly cutting-edge, sophisticated technology. lung infections in children with HIV. They are

“

For children whose livers are damaged by diseases and cancer, transplantation currently is the only option, but sometimes the wait for an organ is too long. Our team is working on a mechanical support system—like dialysis for the liver—as a bridge to transplantation.

But the best long-term hope, I believe, is our research into creating healthy liver cells from the patient’s own stem cells, ideally to help the liver repair itself.

“

GEORGE V. MAZARIEGOS, MD Director, Hillman Center for Pediatric Transplantation 24

WHERE PHYSICIAN-SCIENTISTS WILL DEVELOP TOMORROW’S THERAPIES.

Amazing

Five of the ten stories will be dedicated, 28,000-square-foot lab floors. Each will have open work areas and a convenient conference room to encourage cross-disciplinary research and cooperation. Teams will be able to reconfigure easily. Other floors will house a core of exciting services available to all Children’s researchers: apparatus for high-tech imaging, flow cytometry and ex vivo cellular manipulation, to name a few.

breakthroughs are on the horizon. When completed, the new 300,000-square-foot John G. Rangos Sr. Research Center at Children’s Hospital of Pittsburgh will be one of the best-designed and most impressive medical research laboratories in the country.

The result will be an environment that fosters ingenuity and collaboration.

Better yet, it will bring together multidisciplinary teams of researchers to tackle the diseases of childhood in new, more comprehensive ways.

Because the frontiers of pediatric research are global as well as local, the hub of the building will be a state-of-the-art conference center. Two flexible meeting rooms will adjoin an auditorium with moveable seating for 200. All will be equipped with an audiovisual and teleconferencing system to enable the most productive presentations and symposia.

With 75 percent more laboratory space than the current facility, and with some of the most advanced medical research tools, the new center will enable Children’s to grow its federal research funding to more than $50 million. An estimated 70 principal investigators and their teams will work in the new center.

This new research center will provide the ideal environment to support the tremendous research talent at Children’s today—and to attract even more innovative thinkers to Children’s Hospital in the years to come.

Designed by one of the foremost developers of scientific laboratories in the United States, with input from Children’s researchers, the new center will maximize working laboratory space.

“

Given the talent, ingenuity and enthusiasm of our researchers and their laboratory teams, there is no reason that we cannot be one of the top five programs for pediatric research in the country. On the new Children’s campus, there will be room to fast-track our most important studies.

We will be able to recruit researchers whose promising ideas can be explored. We can invest in the technology that helps us move quickly from the laboratory bench to the bedside.

In addition, we will enable the cross-disciplinary collaboration that generates new tests, treatments and cures. And because many of Children’s programs are approved to offer experimental treatments to today’s patients, we can be a destination of hope for families from around the world.

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DAVID H. PERLMUTTER, MD Physician-in-Chief and Scientific Director

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“

We’re very interested in understanding how certain enzymes break down dietary fats so they can be absorbed, and how this affects digestion and disease. What we’re learning will open doors to new therapies for acute pancreatitis, better ways to feed chronically ill infants, and more effective appetite and weight control.

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MARK E. LOWE, MD, PHD Chief of Pediatric Gastroenterology

“

Our goal at Children’s is twofold—to search for the cause of juvenile rheumatoid arthritis, while recruiting some of the best researchers and clinicians to pave the way to more effective therapies. Everything we do is really focused on how to apply our understanding toward better outcomes for our patients.

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RAPHAEL HIRSCH, MD Chief of Pediatric Rheumatology

“

We are developing a program focused on lung immunology and host defense to address the fact that, worldwide, respiratory infections are the No. 1 killer of children. As we investigate gene therapies and new vaccines, we’ll be able to help doctors around the world win the battle against viral and bacterial infections of the lungs.

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JAY K. KOLLS, MD Chief of Pediatric Pulmonology

“

Curing type 1 diabetes is more than a theoretical possibility. It’s an achievable goal that becomes closer with each discovery in the lab.

We’re very excited because we are about to begin groundbreaking clinical trials to see if the treatments that were so effective on animals will work in patients. A diagnosis of type 1 diabetes can be devastating for children and their families. We hope this trial will have results that are life-altering for patients who MASSIMO M. TRUCCO, MD suffer from the disease.

Chief of Immunogenetics

“

AN ENVIRONMENT THAT FOSTERS INNOVATION AND COLLABORATION.

The best

to the students of the University of Pittsburgh School of Medicine.

and the brightest pediatric medical professionals are attracted here.

What’s more, our excellent clinical outcomes owe a great deal of their success to our outstanding nursing staff. Despite a severe nationwide nursing shortage, Children’s has been successful in its recruiting.

We are developing innovative programs for nurse training and career development— including paths in nursing research—to help guarantee a continued competitive edge in future recruitment.

Today Children’s Hospital of Pittsburgh’s residency program trains nearly 80 percent of the pediatricians and pediatric specialists who practice in the tristate region. It is not only a rich and sought-after training ground, it is one of the top 10 recipients of funding from the prestigious National Institutes of Health.

Few pediatric healthcare centers are able to offer robust fellowship programs in such much-needed areas as pediatric rheumatology, pulmonary medicine, gastroenterology, neurosurgery and otolaryngology. These fellowships train approximately 70 specialists and researchers each year.

These medical professionals, along with recruited physician-researchers from renowned medical institutions, embody a wealth of talent and resources that is difficult to duplicate.

In combination with our advanced-design clinical and research facilities, these experts will extend the reputation of Children’s Hospital around the country—and around the world.

Nearly 200 full-time faculty at Children’s serve as teachers and mentors not only to the pediatric residents and fellows, but also

“

Taking care of children requires tuning in to a child’s developmental level and involving the family in care and the healing process. If a nurse is looking for peers who are dedicated to nursing, an administration that embraces medical technology, and a chance to use the latest medical advances, Children’s Hospital of Pittsburgh is the best place to be.

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DIANE S. HUPP, RN, MSN Chief Nursing Officer

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These are the Caregivers that the Children Need.

“

There’s nothing more satisfying than helping a fellow pediatrician or primary care physician find the most appropriate care for a young patient. We offer a resource that is, frankly, quite uncommon.

Our Diagnostic Referral Service allows physicians to tap into our knowledge base and gain rapid access to a complete range of services within Children’s.

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BASIL J. ZITELLI, MD Chief of Diagnostic Referral Service

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As one of the first hospitals in the nation to establish a weight management and wellness program, our mission is to help children and their families achieve and maintain healthy behaviors for a lifetime. As the waistlines of America’s youth keep expanding, our goal is to help children avoid the complications associated with obesity. We strive to advance our understanding of childhood obesity through research and new developments.

SILVA A. ARSLANIAN, MD

“

Director, Weight Management and Wellness Center

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In critical care, we are bringing the laboratory to the bedside.

This mix of complex, incredibly interesting medicine and the opportunity to connect with families and support them at such an important time is an amazing privilege. What else in the world could be as satisfying?

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ANN E. THOMPSON, MD Director of Critical Care Medicine

“

It’s exciting to work in an environment that fosters so much creativity and has access to such cutting-edge technology. We’re one of only a few pediatric centers in the country, for example, that has successfully implanted an experimental, child-size artificial heart that keeps young patients alive while awaiting a heart transplant. Knowing our work makes a difference for these kids and their families is truly rewarding.

VICTOR O. MORELL, MD

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Chief of Cardiothoracic Surgery

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The concept that a child can have major kidney, bladder or genital reconstruction and essentially have no scars is the standard of care at Children’s. We’re one of only a few centers in the world to provide this state-of-the-art care.

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STEVEN G. DOCIMO, MD, PHD Chief of Pediatric Urology

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THE MOST ADVANCED TRAINING GROUND FOR THE FUTURE. Training Clinical Specialists at Children’s Hospital of Pittsburgh 2003 2004 2005 2006 Residents 116 Fellows 47

118 55

126 66

143 70

Totals 163

173

192

213

Consider

this future: By 2010, Children’s Hospital of Pittsburgh has become one of the nation’s top five pediatric healthcare centers.

The new Children’s serves as a strong economic engine, fueling the region’s economy with more than 1,000 high-paying jobs and a steady stream of revenue. Within the last year, hospital operations directly or indirectly created more than 5,400 jobs in the state, and generated $25 million in state tax revenue.

Already ranked among the country’s best pediatric hospitals by U.S. News & World Report, the Children’s of the future has broadened its scope even further to provide some of the most innovative and effective clinical programs; garners more than $50 million annually in National Institutes of Health research funding; and offers the most competitive pediatric physician training in the country.

All told, Children’s infuses more than $671 million into the Pennsylvania economy, and that includes more than $127 million from out-of-state patients and visitors.

In Lawrenceville, home of Children’s 10-acre campus, a once-vibrant city neighborhood has returned to life in response to the influx of 3,000 employees, the many professionals attending research and educational functions, and the 150,000 patients, families and visitors.

Children’s Hospital of Pittsburgh also has become one of the best places to work for pediatric clinicians, researchers, educators, nurses and other caregivers. As one of the first pediatric healthcare centers to meet Leadership in Energy and Environmental Design (LEED) standards, it can operate more efficiently, and can truly embody our mission of providing a healthy, stress-free environment that facilitates maximum patient safety, and stimulates the best practices in pediatric healthcare.

The benefits of the new Children’s Hospital of Pittsburgh will be many—an anchor in its city neighborhood, a jewel in our region and an unsurpassed resource for healthcare providers across the country and around the world.

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This is the Hospital that Pittsburgh Needs.

AN ECONOMIC ENGINE The building of a new healthcare campus for Children’s Hospital of Pittsburgh is currently the third largest construction project in the region. In November 2003, Children’s Hospital of Pittsburgh commissioned Tripp Umbach Healthcare Consulting, Inc., to study the hospital’s current and projected impact on the economy.

The construction stage will last through 2008 and have a statewide economic impact of $777 million, including nearly 3,300 direct and indirect construction jobs in Allegheny County.

Yet construction is just the beginning. When the hospital begins operation in 2009, we can expect:

JOBS New direct full-time-equivalents

791

New indirect full-time-equivalents 1,423

Many of these jobs require a bachelor’s and advanced degrees, helping the region retain its brainpower and leveraging the presence of our many colleges and universities. Taxes created as a result of Children’s payroll will have a positive impact. In fact, spending in the state’s economy and the generation of fresh revenue from outside the state equaled $24.5 million in 2003. According to the study, the new Children’s ongoing effect on the economy will be statewide.

ANNUAL ECONOMIC IMPACTS Annual out-of-state revenue Annual statewide impact Including: Allegheny County City of Pittsburgh Lawrenceville/Bloomfield

$127 million $671 million $318.9 million $175.0 million $24.5 million

COMMERCIALIZATION OF RESEARCH Further, one of the most interesting possibilities is the commercialization of research.

Already, Children’s has highly specialized labs that perform analyses or create products such as “knockout” models, whose genes are modified to fit any number of traits under study. Researchers worldwide in need of these specialty services can and do include Children’s as a study subcontractor.

Beyond the direct-to-lab customers, it is possible that new discoveries could be spun off to companies such as those that specialize in biotech, precision instrumentation, software or pharmaceuticals. Anywhere from 370 to 800 full-time-equivalent jobs could be generated within five years by Children’s research efforts, either at new or existing companies.

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“

For over 50 years, I have been honored to serve as a trustee and trustee emeritus of Children’s Hospital. This half century has been a period of remarkable advances in caring for children. During this time, this internationally renowned hospital has attracted some of the most brilliant minds in pediatric clinical care and research.

Now, we have a rare opportunity to ensure that the dedicated doctors, researchers, nurses and hospital staff have our support with state-of-the-art facilities to continue their critical work.

Our children and our future depend upon it.

“

HENRY L. HILLMAN

Chairman, Hillman Foundation and Henry L. Hillman Foundation

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Throughout its existence, Children’s has raised the standard of pediatric medicine. The staff has translated their discoveries into improvements in the care of many childhood diseases, including asthma, diabetes and obesity. Children’s does not just save the lives of sick children—it works to improve the lives of all children in our community.

YVONNE COOK

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President, Highmark Foundation Vice President, Highmark Community and Health Initiatives

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In a town of hardworking people, the staff of Children’s Hospital of Pittsburgh do some of the hardest work of all, and they are among the best in the country. Everyone in our organization believes that this world-class care should be there for every child who needs it, and the new campus will ensure this access now, and for the next one hundred years.

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JAMES S. BROADHURST

Chairman & CEO, Eat’n Park Hospitality Group

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Our children will only grow up great if we are willing to provide them the best foundation. Good health is a key building block of that foundation, and that’s why we must support the new Children’s Hospital of Pittsburgh. The hospital’s commitment to children’s health and its expertise on many fronts are critical in the drive to better prepare the next generation for school and life.

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JAMES E. ROHR Chairman & CEO, PNC Financial Services Group, Inc.

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Without a doubt, the new Children’s Hospital of Pittsburgh is a resource for the whole region, but its leaders also share the vision of a revitalized Lawrenceville. We warmly welcome Children’s to our historic neighborhood, and we anticipate many mutual benefits for the institution and the community.

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KATE TRIMBLE Executive Director, Lawrenceville Corporation

SECURING OUR PLACE IN THE WORLD Children’s Hospital of Pittsburgh has shown its leadership in many remarkable ways: A pediatric trauma program that is one of the busiest in the country, admitting almost 1,700 children in 2006 alone The first Diagnostic Referral Service, created as a resource for pediatricians everywhere who struggle to diagnose children with complicated illnesses One of the world’s first programs for pediatric otolaryngology to improve treatment of some of childhood’s most common illnesses The country’s first pediatric transplantation center, which continues to achieve survival rates significantly higher than national averages—across all types of transplants The region’s only pediatric Cardiac Intensive Care Unit (CICU), equipped to care for the toughest medical conditions that compromise young hearts An extensive research program that is among the top 10 pediatric hospitals by share of National Institutes of Health awards A Residency in Pediatrics program that trains nearly 80 percent of the pediatricians and pediatric specialists who practice in the tristate region One of the first pediatric hospitals to embrace computerized provider order entry, a nationally recognized standard for improving patient safety Consistently ranked by U.S. News & World Report among the best pediatric hospitals in the country

CAPITAL CAMPAIGN GOAL: $100 MILLION

NEW CAMPUS BUILDINGS: $50 MILLION Each building of the new campus will integrate the best thinking on environments for children, families and healthcare workers. Infrastructure will encourage collaboration and will be modular—to meet our needs for the next 100 years. The 10-acre campus will comprise: Clinical Services Building— a nine-story hospital with 262 beds

Family Residence Building with fitness and daycare centers

John G. Rangos Sr. Research Center— a 10-story lab with room for 70 research teams

Medical and Administrative Office Building Campus Mechanical Equipment Building

Mid-Site Garage and Terrace Garden

ADVANCED CLINICAL PROGRAMS: $25 MILLION Within three to five years, Children’s has the potential to create and expand clinical programs that will set international standards—centers of excellence that will incorporate the latest technology and research findings to help shape a new era in pediatric healthcare. Among the centers envisioned: Comprehensive Fetal Intervention Center

National Pediatric Diagnostic Center

Comprehensive Intestinal Care Center

Weight Management and Wellness Center

Hillman Center for Pediatric Transplantation

Minimally Invasive Pediatric Surgery Center

NEW AND EXPANDED RESEARCH PROGRAMS: $25 MILLION Our research funding, which includes significant support from the National Institutes of Health, will have more than doubled to $50 million by 2009. Combined with our landmark facility, this will enable Children’s to attract even more talented and respected researchers. With additional funds, we can implement an institute model within our research program, where the focus would be on the most high-impact, novel ideas, especially in the promising realm of molecular and cellular research. This model would reward the pursuit of new developments, and would free successful principal investigators to concentrate directly on research. Areas in which Children’s has unique advantages can be expanded into national resources such as: The Center for Childhood Cancer Research

The Center for the Study of Genetic Modifiers

The Vaccine Research Center

The Fragile X Syndrome Center

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2006-2007 CHILDREN’S HOSPITAL OF PITTSBURGH

BOARD OF TRUSTEES Mary Jo Howard Dively, Esq. Chair Vincent C. Deluzio, Esq. Vice Chair Howard W. Hanna III Vice Chair Roger A. Oxendale President Lorina W. Wise, Esq. Secretary Mark J. Giaquinto Treasurer

Jeffrey S. Broadhurst Lawrence J. Butler, MD* Chief Justice Ralph J. Cappy Ronald R. Davenport Jr. Robert A. DeMichiei Douglas P. Dick William F. Donaldson, MD George K. Gittes, MD* Lawrence N. Gumberg Martha Hartle Munsch, Esq. Robert M. Hernandez Mark J. Laskow Arthur S. Levine, MD David H. Perlmutter, MD* John G. Rangos Sr.

Jeffrey A. Romoff Catharine M. Ryan Edwin F. Scheetz Jr. Joseph C. Walton HONORARY MEMBERS Virginia W. Ahlbrandt Robert L. Becker Jr. James S. Broadhurst Margaret Childs Helen S. Faison, PhD Henry L. Hillman Stephanie F. Mallinger Jean A. Robinson Mason Walsh Jr.

FOUNDATION TRUSTEES Catharine M. Ryan Chair Mary Jo Howard Dively, Esq. Vice Chair Joseph C. Walton Interim President Jodi K. Innocent, Esq. Secretary Bernadette M. Scheid Treasurer

Thomas G. Bigley Leslie W. Braksick, PhD Rebecca Cost Snyder Vincent C. Deluzio, Esq. Douglas P. Dick William F. Donaldson, MD Helen S. Faison, PhD Lawrence N. Gumberg Howard W. Hanna III Martha Hartle Munsch, Esq.

William H. Isler Arthur S. Levine, MD Roger A. Oxendale* Janet F. Palumbo Denise M. Pampena, Esq. David H. Perlmutter, MD* John G. Rangos Sr. Edwin F. Scheetz Jr. Ronald L. Violi

NEW HOSPITAL CAPITAL CAMPAIGN CABINET Thomas G. Bigley Leslie W. Braksick, PhD Mary Jo Howard Dively, Esq.

* ex officio

Howard W. Hanna III DeAnn Aston Marshall Roger A. Oxendale Denise M. Pampena, Esq.

Catharine M. Ryan Edwin F. Scheetz Jr. Joseph C. Walton

A TREASURE FOR THE REGION, A RESOURCE FOR THE WORLD

To Our Caring Benefactors, Pittsburgh has not built its reputation by doing things in a small way. From our role in steel and manufacturing, to our breakthroughs in technology and biomedicine, we have demonstrated our ability to pull together, and our accomplishments are world-scale. Today, we have the opportunity to fulfill a desperate need and, in doing so, achieve the next great triumph for this region.

Our need for a new children’s hospital is a once-in-our-lifetime opportunity. We already have in place the region’s commitment to healthcare as an industry, a wealth of educational and research resources, and cutting-edge technology. And as always, Children’s continues on a daily basis to save lives and to generously provide the best care to our region’s children, regardless of their means.

All of it has been proven: now we have a chance to create one of the top pediatric care centers in the world—the Children’s Hospital of the future.

As the region’s only dedicated pediatric institution, Children’s constant push for excellence—to improve care and find cures through research—is enhanced by our partnerships with UPMC and the University of Pittsburgh.

The foresight of our early leaders has been confirmed: a dedicated children’s hospital is a sound regional investment. And it is the right thing to do.

Right now, we have the power to expand the reach, the resources and the reputation of Children’s Hospital of Pittsburgh. I urge you to join us. Together we can plan the future of healthcare for generations to come, and give the children a legacy of the best care in the world.

Sincerely,

Roger A. Oxendale President and Chief Executive Officer

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1251 Waterfront Drive, Floor 5 • Pittsburgh PA 15222-4209 1-877-CHP-GIVE (1-877-247- 4483)

Acknowledgements: Photography: Mark Bolster, David A. DeNoma, Ric Evans, Bill Exler, Ronald Fontana, Jonas Photography, Kathryn Komperda, Lisa Kyle, Annie O'Neill, LeonWinkowski, Jason Yurkovich. Retouching by Mark Sherer.

All architectural renderings by Astorino©2006. Illustrations by Dave Klug©2006.

Neighborhood photos by Tim Fabian©2006 (Courtesy of PPND). ©2006 Children’s Hospital of Pittsburgh Foundation, Pittsburgh, PA. All rights reserved.