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insight Summer 2021

Research and Scholarship

Welcome to the summer 2021 issue of Insight, a newsletter celebrating the accomplishments of our community of scholars. We aim to spotlight insights from people at the Dugoni School working in all areas of scholarship, including clinical or biomedical research, the scholarship of teaching and learning, improvement of the health care system, and professional partnerships that advance the field. Research Lab Tour, Dugoni School of Dentistry A brief behind-the-scenes look at the research laboratory on the 4th floor of the dental school, led by Harmony Matshik Dakafay, laboratory manager. View video


insight

Research and Scholarship

Research in the Spotlight Neanderthal cranial remains from Baume Moula-Guercy (Soyons, Ardèche, France) What is it? An in-depth examination of a collection of skull fragments found in an excavation in the Rhone Valley which date back to as long as 130,000 years ago. What problem does it aim to solve? Researchers are seeking to understand how Neanderthal crania changed over time and when these changes occurred. How does it work? The researchers examined the fragments, employing CT scans and virtual reconstruction, closely focusing on the frontal. They compared them to a set of recent human cranial samples from the Dugoni School’s Center for Dental History and Craniofacial Study. What are the findings? The research identifies the unique combination of morphological features of crania from this location and timeframe — some are similar to those of early Neanderthals, but others are more similar to Late Neanderthals.

Cranial fragments from Soyons, France.

What are the next steps? The Neanderthal cranial remains from Baume Moula-Guercy are a valuable resource for future studies to understand the evolution of Neanderthals. Source “Neanderthal cranial remains from Baume Moula-Guercy (Soyons, Ardèche, France)”, Am J Phys Anthropol. 2021;175:201–226. https://is.gd/kuneca Authors Gary D. Richards, Department of Biomedical Sciences, Dugoni School of Dentistry, University of the Pacific Gaspard Guipert, Institut de Paléontologie Humaine, Fondation, Albert Ier Prince de Monaco, Paris, France Rebecca S. Jabbour, Department of Biology, Saint Mary’s College of California, Moraga, California Alban R. Defleur, CEPAM - UMR 7264 CNRS, Université de Nice, Nice, France


insight

Research and Scholarship

Student Preferences Impact Outcome of Flipped Classroom in Dental Education: Students Favoring Flipped Classroom Benefited More

What is it? A study looking at the relationship between how students feel about the flipped classroom model and their learning outcomes. What problem does it aim to solve? “Many reports in dental education showed that student learning improved with the flipped classroom method. However, there are few reports that describe how different subsets of students may benefit from the flipped classroom.” The researchers aimed to test the hypothesis that students who preferred the flipped classroom style did better on quizzes. How does it work? The researchers used a flipped classroom module used to teach first-year DDS students, and then analyzed their performance on the quizzes and their written assignments, as well as the time they spent studying and discussing the course materials and topics. What are the findings? Guided self-study that includes work that needs to be submitted strongly correlates with better academic performance in the course. “Students’ self-evaluated understanding of content significantly improved after finishing the assignment and discussion compared to finishing the pre-class activity alone…Our results indicated that students favoring the flipped classroom method spent more time on the assignment, understood the content better, and performed better on assessments than students who prefer traditional lectures.” What are the next steps? Educators designing courses for professional students that include the flipped classroom method need to prioritize including components that engage students and require them to do some work throughout the course to demonstrate what they’ve learned. Source Xiao, Nan, Der Thor, and Meixun Zheng. 2021. “Student Preferences Impact Outcome of Flipped Classroom in Dental Education: Students Favoring Flipped Classroom Benefited More” Education Sciences 11, no. 4: 150. https://is.gd/jaboru Authors Nan Xiao, Department of Biomedical Sciences, Arthur A. Dugoni School of Dentistry, University of the Pacific, San Francisco Der Thor, Department of Biomedical Sciences, Arthur A. Dugoni School of Dentistry, University of the Pacific, San Francisco Meixun Zheng, Academic Affairs, Arthur A. Dugoni School of Dentistry, University of the Pacific, San Francisco


insight

Research and Scholarship

Congratulations to Dugoni School faculty, staff, student and resident researchers involved in the following research publications in the last few months as sourced by Scopus, the abstract and citation database of peer-reviewed literature. Visit the abstract links to learn more. Mortada, I., Farah, R., Nabha, S., Ojcius, D.M., Fares, Y., Almawi, W.Y., Sadier, N.S. Immunotherapies for Neurodegenerative Diseases (2021) Frontiers in Neurology, 12, art. no. 654739. View › Fakhrzadeh, A., Saghiri, M.A., Morgano, S.M., Sullivan, A. Tissue reaction to novel customized calcium silicate cement based dental implants. A pilot study in the dog (2021) Journal of Materials Science: Materials in Medicine, 32 (6), art. no. 61. View › Yoon, A., Abdelwahab, M., Liu, S., Oh, J., Suh, H., Trieu, M., Kang, K., Silva, D. Impact of rapid palatal expansion on the internal nasal valve and obstructive nasal symptoms in children (2021) Sleep and Breathing, 25 (2), pp. 1019-1027. View › Stelzer, I.A., Ghaemi, M.S., Han, X., Ando, K., Hédou, J.J., Feyaerts, D., Peterson, L.S., Rumer, K.K., Tsai, E.S., Ganio, E.A., Gaudillière, D.K., Tsai, A.S., Choisy, B., Gaigne, L.P., Verdonk, F., Jacobsen, D., Gavasso, S., Traber, G.M., Ellenberger, M., Stanley, N., Becker, M., Culos, A., Fallahzadeh, R., Wong, R.J., Darmstadt, G.L., Druzin, M.L., Winn, V.D., Gibbs, R.S., Ling, X.B., Sylvester, K., Carvalho, B., Snyder, M.P., Shaw, G.M., Stevenson, D.K., Contrepois, K., Angst, M.S., Aghaeepour, N., Gaudillière, B. Integrated trajectories of the maternal metabolome, proteome, and immunome predict labor onset (2021) Science Translational Medicine, 13 (592), art. no. eabd9898. View › Xu, K., Hasan, S.E., Chen, G., Liu, S., Chambers, D.W., Xu, T. Measuring orthodontic treatment impact: Description or judgment, challenge or result (2021) American journal of orthodontics and dentofacial orthopedics : official publication of the American Association of Orthodontists, its constituent societies, and the American Board of Orthodontics, 159 (5), pp. e389-e397. View › Richards, G.D., Guipert, G., Jabbour, R.S., Defleur, A.R. Neanderthal cranial remains from Baume Moula-Guercy (Soyons, Ardèche, France) (2021) American Journal of Physical Anthropology, 175 (1), pp. 201-226. View › Sherwood, R.J., Oh, H.S., Valiathan, M., McNulty, K.P., Duren, D.L., Knigge, R.P., Hardin, A.M., Holzhauser, C.L., Middleton, K.M. Bayesian approach to longitudinal craniofacial growth: The Craniofacial Growth Consortium Study (2021) Anatomical Record, 304 (5), pp. 991-1019. View › Bhatia, S., Nagendrababu, V., Peters, O.A., Fawzy, A., Daood, U. Evaluation of usage-induced degradation of different endodontic file systems (2021) Scientific reports, 11 (1), p. 9027. View ›


insight

Research and Scholarship

Xiao, N., Thor, D., Zheng, M. Student preferences impact outcome of flipped classroom in dental education: Students favoring flipped classroom benefited more (2021) Education Sciences, 11 (4), art. no. 150. View › Tsotsis, P., Dunlap, C., Scott, R., Arias, A., Peters, O.A. A survey of current trends in root canal treatment: access cavity design and cleaning and shaping practices (2021) Australian Endodontic Journal, 47 (1), pp. 27-33. View › Kanellopoulos, J.M., Almeida-da-Silva, C.L.C., Rüütel Boudinot, S., Ojcius, D.M. Structural and Functional Features of the P2X4 Receptor: An Immunological Perspective (2021) Frontiers in Immunology, 12, art. no. 645834. View › Nguyen, B., Alpagot, T., Oh, H., Ojcius, D., Xiao, N. Comparison of the effect of cigarette smoke on mesenchymal stem cells and dental stem cells (2021) American Journal of Physiology - Cell Physiology, 320 (2), pp. C175-C181. View › Xiao, N., Thor, D., Yu, W.Y. Neurotrophins BDNF and NT4/5 accelerate dental pulp stem cell migration (2021) Biomedical Journal. View › Bianchi, J., Ruellas, A., Prieto, J.C., Li, T., Soroushmehr, R., Najarian, K., Gryak, J., Deleat-Besson, R., Le, C., Yatabe, M., Gurgel, M., Turkestani, N.A., Paniagua, B., Cevidanes, L. Decision Support Systems in Temporomandibular Joint Osteoarthritis: A review of Data Science and Artificial Intelligence Applications (2021) Seminars in Orthodontics. View › Knigge, R.P., McNulty, K.P., Oh, H., Hardin, A.M., Leary, E.V., Duren, D.L., Valiathan, M., Sherwood, R.J. Geometric morphometric analysis of growth patterns among facial types (2021) American Journal of Orthodontics and Dentofacial Orthopedics. View › Nagendrababu, V., Murray, P.E., Ordinola-Zapata, R., Peters, O.A., Rôças, I.N., Siqueira, J.F., Jr., Priya, E., Jayaraman, J., J Pulikkotil, S., Camilleri, J., Boutsioukis, C., Rossi-Fedele, G., Dummer, P.M.H. PRILE 2021 guidelines for reporting laboratory studies in Endodontology: A consensus-based development (2021) International Endodontic Journal. View › Peng, H.-H., Wu, C.-Y., Hsiao, Y.-C., Martel, J., Ke, P.-Y., Chiu, C.-Y., Liau, J.-C., Chang, I.-T., Su, Y.-H., Ko, Y.-F., Young, J.D., Ojcius, D.M. Ganoderma lucidum Stimulates Autophagy-Dependent Longevity Pathways in Caenorhabditis elegans and Human Cells (2021) Aging, 13 (10), pp. 13474-13495. View ›


insight

Research and Scholarship

Saghiri, M.A., Aminsobhani, M., Gutmann, J.L., Kawai, T., Nath, D., Hirschberg, C. Effect of Diabetes on Rotary Instrumentation of Dentin (2021) Journal of Endodontics. View › Al Turkestani, N., Bianchi, J., Deleat-Besson, R., Le, C., Tengfei, L., Prieto, J.C., Gurgel, M., Ruellas, A.C.O., Massaro, C., Aliaga Del Castillo, A., Evangelista, K., Yatabe, M., Benavides, E., Soki, F., Zhang, W., Najarian, K., Gryak, J., Styner, M., Fillion-Robin, J.-C., Paniagua, B., Soroushmehr, R., Cevidanes, L.H.S. Clinical decision support systems in orthodontics: A narrative review of data science approaches (2021) Orthodontics and Craniofacial Research. View › Cong, A., Massaro, C., Ruellas, A.C.D.O., Barkley, M., Yatabe, M., Bianchi, J., Ioshida, M., Alvarez, M.A., Aristizabal, J.F., Rey, D., Cevidanes, L. Dental long axes using digital dental models compared to cone-beam computed tomography (2021) Orthodontics and Craniofacial Research. View › Hardin, A.M., Knigge, R.P., Oh, H.S., Valiathan, M., Duren, D.L., McNulty, K.P., Middleton, K.M., Sherwood, R.J. Estimating Craniofacial Growth Cessation: Comparison of Asymptote- and Rate-Based Methods (2021) Cleft Palate-Craniofacial Journal. View › Saghiri, M.A., Dadvand, S., Abdolmaleki, A. The evaluation of physical properties of a polyurethane expandable endodontic sealer: a preliminary study (2021) Australian Endodontic Journal. View › Zheng, M., Louie, K. Promoting student online engagement and interaction with cloud-based technology (2021) Journal of Dental Education. View › Chambers, D.W., Brady, M. Barriers and opportunities for dental school faculty research (2021) Journal of Dental Education. View › Cho, J.Y., Choi, T.-W., Kim, S.H., Ahnn, J., Lee, S.-K. Morphological characterization of small, dumpy, and long phenotypes in Caenorhabditis elegans (2021) Molecules and Cells, 44 (3), pp. 160-167. View › Saghiri, M.A., Nath, D., Rahmani, B., Amini, S., Karamifar, K., Peters, O.A. The effect of diabetes on Fracture Resistance of Teeth: An in vitro study (2021) Australian Endodontic Journal. View › Parizotto, J.D.O.L., Peixoto, A.P., Borsato, K.T., Bianchi, J., Vendramini Pittoli, S., Tonello, C., Gonçalves, J.R. Craniofacial and airway morphology of individuals with oculoauriculovertebral spectrum (2021) Orthodontics and Craniofacial Research. 7JFXl


insight

Research and Scholarship

Karamifar, K., Shirali, D., Saghiri, M.A., Abbott, P.V. Retromolar canal infiltration as a supplement to the inferior alveolar nerve block injection: an uncontrolled clinical trial (2021) Clinical Oral Investigations. View › Iacono, F., Pirani, C., Gatto, M.R., Prati, C., Peters, O.A. Combining apical torsional load and cyclic fatigue resistance of NiTi instruments: New approach to determine the effective lifespan of rotary instruments (2021) Australian Endodontic Journal. View ›

Profile for Dugoni School of Dentistry

Insight - Summer 2021  

Whether you are involved in clinical research, biomedical research, the scholarship of teaching and learning, improvement of the health care...

Insight - Summer 2021  

Whether you are involved in clinical research, biomedical research, the scholarship of teaching and learning, improvement of the health care...

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