Insight Fall 2023

insight Fall 2023

Research and Scholarship

Welcome to the Fall 2023 issue of Insight, a newsletter celebrating the accomplishments of our community of scholars. We aim to spotlight insights from people at the Dugoni School working in all areas of scholarship, including clinical or biomedical research, the scholarship of teaching and learning, improvement of the health care system, and professional partnerships that advance the field.

Faculty Member Receives NIH Award to Study Immune Biomarkers for Predicting Oral Cancer Dr. Xiaoyuan Han, assistant professor in the Department of Biomedical Sciences at University of the Pacific, Arthur A. Dugoni School of Dentistry, was recently awarded a Support for Research Excellence-First Independent Research (SuRE-First) Award from the National Institutes of Health (NIH) on the topic “Single-cell immune landscape in the oral dysplasia’s malignant transformation.”

Han is the first researcher at University of the Pacific to receive the SuRE-First award, which aims to provide students, especially those from underrepresented groups, with research opportunities and enrich the research environment at institutions having limited NIH research support.

Systemic immune profiling using suspension mass cytometry (CyTOF).

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Research and Scholarship

The award grants Han $702,000 for a four-year research project to identify immune features that predict the malignant transformation of cells in the mouth to oral cavity squamous cell carcinoma (OCSCC) using state-of-the-art single-cell analysis and bioinformatic AI tools.

“Our students will develop multiplex immune imaging assay on clinical dental biopsies and apply innovative bioinformatic AI tools on data analysis in my research project, which is a collaboration with Stanford School of Medicine,” said Han. “OCSCC is an aggressive cancer with a poor prognosis, and Dr. Han’s work could help to identify patients needing early care and increase our ability to provide personalized medical care to treat these patients,” said Dr. David Ojcius, assistant dean for research and co-chair of the Department of Biomedical Sciences.

Pacific Collaborating with Stanford to Train Next Generation of Clinical Oral Health Researchers University of the Pacific, Arthur A. Dugoni School of Dentistry is collaborating with Stanford University on an ambitious program aimed at bridging the gap between biomedical research and clinical practice.

A $3.8 million grant was recently awarded by the NIH’s National Institute of Dental and Craniofacial Research (NIDCR) to fund the Pacific-Stanford PRIMED Program.

New knowledge on oral disease prevention and clinical care is constantly emerging, but much of it does not make it into clinical practices. The five-year grant will allow Pacific to train the next generation of clinical oral health researchers who are equipped to translate research into practice.

There is also a growing need for more clinician-scientists in the workforce.

“As a clinician, it’s profoundly gratifying to help one patient at a time, but as a researcher we can help populations at a time,” said David Lam, professor and chair of the Dept. of Oral & Maxillofacial Surgery and associate dean for medical integration.

Lam is co-leading the grant with Rebecca Moazzez, professor and chair of the Dept. of Preventive and Restorative Dentistry and director of the Center for Innovation and Translation at Pacific and two researchers from Stanford— Ruth O’Hara, professor and senior associate dean for research and John Sunwoo, professor and associate dean for academic affairs.

“We are extremely excited to formalize our research and educational collaboration with our colleagues at Dugoni,” Sunwoo said. “We have collaborated informally for several years with Dr. David Lam and are thrilled to be part of this new initiative to train the next generation of oral health clinician-scientists.”

The partnership between the schools draws on Pacific’s strength in dental education and training and Stanford’s robust clinical and translational research. “Putting the two together, we synergistically help each other,” Lam said.

The program will transform dental education at the Dugoni School by making clinical research training mandatory for all first-year students and residents.

“Our students will be in a different league compared to dental graduates around the country,” Moazzez said. “Not only will they have their excellent dental training, but they will now also receive excellent clinical research training, together with a certificate from Stanford University, which will equip them for practice-based research here at the dental school, and in the future, in their private practices.”

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Research and Scholarship

Research studies conducted as part of the training will focus on three areas: oral cancer, sleep medicine and developing a Pacific-Stanford biobank.

The oral cancer study is aimed at detecting cancer earlier. Sleep apnea research will expand work currently underway at the Dugoni School to evaluate the effectiveness of new treatment options. The biobank project involves collecting blood, saliva, tissue, and demographic information to create a robust collection of patient samples.

“At every patient appointment, students will be trained on obtaining informed consent and collecting saliva or blood samples,” Moazzez said. “The initial advantage is bringing research culture into the day-to-day operations of the clinic. The collected data and samples will then help drive future research projects and collaborations.”

The expanded focus on research at the Dugoni School will also help advance the work of Pacific’s Center for Innovation and Translation located on the San Francisco Campus. The center’s goal is to support students, residents, and faculty, so that clinical research becomes the easiest thing a clinician can do. The center also aims to build on existing and develop further collaborations with commercial companies and startups to test new products and innovations and facilitate translation of innovation into clinical practice.

A grant from the NIDCR / NIH will fund a collaboration between Pacific and Stanford to train the next generation of clinical oral health researchers.

In Other News

Dugoni School student Sahar Rahnemabayat presented at the 28th annual Hinman Symposium which took place in November 10-12, 2023 in Memphis, TN, on the research topic “Inferior Alveolar Nerve Block in Pediatric Patients: A Quantitative Assessment. Gary Richards served as mentor on this project.

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Research and Scholarship

Webinar

Missed the “How to Be a Good Scientific Manuscript Reviewer” webinar or want to watch it again? A recording of the presentation is now available on ADEA eLearn.

To access this recording, go to this link https://is.gd/rozego and log in. You can also find this product in your Dashboard after you’ve logged in.

Interested in earning an ADEA Micro-credential related to this webinar? Visit ADEA eLearn to more about the available topics and requirements for each micro-credential.

Questions? Contact ADEA eLearn staff at learn@adea.org

Exosomes in Multiple Sclerosis and Alzheimer’s Disease — Adversary and Ally What is it?

A review of how exosomes play a role in several conditions and could also be the key to therapies for them and other conditions. Extracellular vesicles (EVs) are small, membrane-enclosed particles that cells secrete, and which carry proteins, lipids, and nucleic acids. Exosomes are a type of EV. As multivesicular endosomes form, they incorporate cytoplasmic bits and contents, transforming into exosomes. The exosomal cargo mirrors the identity and current physiological state of the cell that secretes them. EVs transport signaling molecules and play crucial roles in processes like myelination, trophic support, synaptic plasticity, and antigen presentation in a healthy state.

What problem does it aim to solve?

EVs can move between cells in the CNS and even cross the blood-brain barrier, influencing organs outside the CNS and vice versa. In disease, CNS-derived or peripherally-transported EVs can carry harmful molecules, contributing to neuroinflammation and neurodegeneration. However, they could also help deliver therapeutics.

How does it work?

EVs show promise for treating CNS diseases through various delivery methods like intravenous, intraperitoneal, subcutaneous, or intranasal routes. They’ve been successfully used both broadly and locally for therapeutic effects. To enhance precision, specific strategies are employed, such as using ligands or antibodies to target cells. In Alzheimer’s disease, intranasal administration is being explored, with a clinical trial underway for nasal administration of exosomes. Clinical trials with EVs have accelerated, driven partly by interest in COVID-19, but the field is still at an early stage, with most studies in early phases and no completed phase III trials.

What are the real-world implications?

Despite increased interest and research in the last decade, the use of EVs in treating CNS diseases is still in early stages. There’s growing potential for EVs to serve as biomarkers and therapeutics for conditions like multiple sclerosis (MS) and Alzheimer’s disease (AD). However, certain technical challenges need addressing before EVs can be used in patient care.

What are the next steps?

Ongoing technological advancements aim to unlock the potential of EVs for precise drug delivery to combat neuroinflammation and neurodegeneration, ultimately improving conditions like MS, AD, and other CNS diseases.

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Research and Scholarship

Source “Exosomes in multiple sclerosis and Alzheimer’s disease – Adversary and ally”, Biomedical Journal, article in press https://www.sciencedirect.com/science/article/pii/S2319417023001026 Author Norina Tang, Department of Periodontics, University of the Pacific, Arthur A. Dugoni School of Dentistry, 155 Fifth Street, San Francisco, CA 94103, USA Department of Laboratory Medicine, San Francisco Veterans Affairs Health Care System, San Francisco, CA 94121, USA

Extracellular vesicle (EV) classes, origins and characteristics

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Research and Scholarship

Recent Publications Congratulations to Dugoni School faculty, staff, student and resident researchers involved in the following research publications in the last few months: Coppelson K., Summersgill I., Hatcher D., Nguyen G., Pada H., Stewart H., Herre T., Hansen M., Zaghi S. Does Head and Neck Posture Affect Cone-Beam Computed Tomography Assessment of the Upper Airway? (2023), Journal of Oral and Maxillofacial Surgery DOI: 10.1016/j.joms.2023.01.016 | View › Sadowsky S.J. Peri-implantitis after 40 years: Evidence, mechanisms, and implications: A mapping review (2023), Journal of Prosthetic Dentistry DOI: 10.1016/j.prosdent.2023.02.008 | View › Brand L., Dunlap C.A., Scott R., Arias A., Peters O. An in vitro evaluation of the WIRELE-x electronic apex locator (2023), Australian Endodontic Journal, 49 (S1), pp. 41 - 45 DOI: 10.1111/aej.12688 | View › Martel J., Chang S.-H., Chevalier G., Ojcius D.M., Young J.D. Influence of electromagnetic fields on the circadian rhythm: Implications for human health and disease (2023), Biomedical Journal, 46 (1), pp. 48 - 59 DOI: 10.1016/j.bj.2023.01.003 | View › Yoon A., Gozal D., Kushida C., Pelayo R., Liu S., Faldu J., Hong C. A roadmap of craniofacial growth modification for children with sleep-disordered breathing: a multidisciplinary proposal (2023), Sleep, 46 (8), art. no. zsad095 DOI: 10.1093/sleep/zsad095 | View › Gajendra S., McIntosh S., Ghosh S. Effects of tobacco product use on oral health and the role of oral healthcare providers in cessation: A narrative review (2023), Tobacco Induced Diseases, 21, art. no. 12 DOI: 10.18332/tid/157203 | View › Yoon A., Kim T.K., Abdelwahab M., Nguyen M., Suh H.Y., Park J., Oh H., Pirelli P., Liu S.Y.-C. What changes in maxillary morphology from distraction osteogenesis maxillary expansion (DOME) correlate with subjective and objective OSA measures? (2023), Sleep and Breathing, 27 (5), pp. 1967 - 1975 DOI: 10.1007/s11325-022-02761-5 | View › Hassani M., Leda A., Porolnik W., Falkowski M., Rebis T., Piskorz J., Popenda L., Wicinski M., Mlynarczyk D.T., Düzgüneş N., Marszall M.P. Synthesis, Electrochemical and Photochemical Properties of Sulfanyl Porphyrazine with Ferrocenyl Substituents (2023), Molecules, 28 (13), art. no. 5215 DOI: 10.3390/molecules28135215 | View › Saghiri M.A., Saghiri A.M., Samadi E., Nath D., Vakhnovetsky J., Morgano S.M. Neural network approach to evaluate the physical properties of dentin (2023), Odontology, 111 (1), pp. 68 77 DOI: 10.1007/s10266-022-00726-4 | View › Chan C.W., Romeo V.R., Lee A., Zhang C., Neelakantan P., Pedullà E. Accumulated Hard Tissue Debris and Root Canal Shaping Profiles Following Instrumentation with Gentlefile, One Curve, and Reciproc Blue (2023), Journal of Endodontics, 49 (10), pp. 1344 - 1351 DOI: 10.1016/j. joen.2023.07.019 | View ›

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Research and Scholarship

Milnes M., Amos-Terrell D., Barney-Knox B., Clarke J., Foss T., Selby M., Walls M., Bick J. Decreasing the Risk for Transmission of SARS-CoV-2 During In-Person Visitation Within a State Prison System (2023), Journal of Correctional Health Care DOI: 10.1089/jchc.21.12.0134 | View › Almeida-da-Silva C.L.C., Savio L.E.B., Coutinho-Silva R., Ojcius D.M. The role of NOD-like receptors in innate immunity (2023), Frontiers in Immunology, 14, art. no. 1122586 DOI: 10.3389/fimmu.2023.1122586 | View › Baquero B., Gillot M., Cevidanes L., Turkestani N.A., Gurgel M., Leclercq M., Bianchi J., Yatabe M., Ruellas A., Massaro C., Aliaga A., Castrillon M.A.A., Rey D., Aristizabal J.F., Prieto J.C. Automatic Landmark Identification on IntraOralScans (2023), Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics), 13746 LNCS, pp. 32 42 DOI: 10.1007/978-3-031-23179-7_4 | View › Said-Sadier N., Sayegh B., Farah R., Abbas L.A., Dweik R., Tang N., Ojcius D.M. Association between Periodontal Disease and Cognitive Impairment in Adults (2023), International Journal of Environmental Research and Public Health, 20 (6), art. no. 4707 DOI: 10.3390/ijerph20064707 | View › Einhaus J., Han X., Feyaerts D., Sunwoo J., Gaudilliere B., Ahmad S.H., Aghaeepour N., Bruckman K., Ojcius D., Schürch C.M., Gaudilliere D.K. Towards multiomic analysis of oral mucosal pathologies (2023), Seminars in Immunopathology, 45 (1), pp.

111 - 123 DOI: 10.1007/s00281-022-00982-0 | View › Oza S., Lai G., Peters O.A., Chen J., Karabucak B., Scott R., Galicia J.C. The Influence of Cone Beam Computed Tomography-Derived 3D-Printed Models on Endodontic Microsurgical Treatment Planning and Confidence of the Operator (2023), Journal of Endodontics, 49 (5), pp. 521 - 527. e2 DOI: 10.1016/j.joen.2023.02.004 | View › Casino A.J., LeRoy J., Jr., Reddy R., Lam D.K. Refined Topical 5-Fluorouracil Technique for the Targeted Treatment of Odontogenic Keratocysts (2023), Journal of Oral and Maxillofacial Surgery, 81 (1), pp. 95 - 100 DOI: 10.1016/j.joms.2022.09.010 | View › Chainani-Wu N., Gopal-Murthy V., Wu A., Marinkovich M.P. Localized CO2 laser treatment of a recalcitrant oral ulceration in pemphigus vulgaris (2023), Clinical advances in periodontics, 13 (1), pp. 38 - 41 DOI: 10.1002/cap.10210 | View › Alvear Fa B., Reid L., Radjaeipour G. Behavioural video to navigate predoctoral dental students toward safer practice (revision of EJE-214739) (2023), European Journal of Dental Education, 27 (4), pp. 841 - 848 DOI: 10.1111/eje.12874 | View › Ngan P., Hosseini H.R., Tai S.K., Andrews L.J., II, Xiang J. A comparison of skeletal and dental changes in patients with a Class II relationship treated with clear aligner mandibular advancement and Herbst appliance followed by comprehensive orthodontic treatment (2023), American Journal of Orthodontics and Dentofacial Orthopedics DOI: 10.1016/j.ajodo.2023.08.015 | View ›

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Cuenin K., Chen J., Tai S.K., Lee D., Gerges G., Oh H. Caries detection and characterization in pediatric patients using iTero 5D near-infrared technology (2023), American Journal of Orthodontics and Dentofacial Orthopedics DOI: 10.1016/j.ajodo.2023.06.026 | View › Fears N.E., Sherrod G.M., Templin T.N., Bugnariu N.L., Patterson R.M., Miller H.L. Community-based postural control assessment in autistic individuals indicates a similar but delayed trajectory compared to neurotypical individuals (2023), Autism Research, 16 (3), pp. 543 - 557 DOI: 10.1002/aur.2889 | View › Bernal G., Ruiz L., Aellos F., Salazar C., Sadowsky S.J. Clinical and cone beam computed tomography outcomes of maxillary anterior implant restorations after immediate implant placement with interim restorations: A 1- to 14-year retrospective analysis (2023), Journal of Prosthetic Dentistry DOI: 10.1016/j.prosdent.2023.05.028 | View › Tittle M., Dunlap C.A., Scott R., Arias A., Davis S., Peters O. Accuracy of the KontrolFlex AccuFile when used with the Root ZX electronic apex locator in vitro (2023), Australian Endodontic Journal, 49 (S1), pp. 253 - 258 DOI: 10.1111/aej.12727 | View › El Hachem C., Chedid J.C.A., Nehme W., Kaloustian M.K., Ghosn N., Rabineau M., Kharouf N., Haikel Y., Mancino D. The Contribution of Various In Vitro Methodologies to Comprehending the Filling Ability of Root Canal Pastes in Primary Teeth (2023), Bioengineering, 10 (7), art. no. 818 DOI: 10.3390/bioengineering10070818 | View › Zheng M., Cuenin K., Lyon C., Bender D. An Exploratory Study of Dental Students’ Use of Whiteboard Animated Videos as Supplementary Learning Resources in Basic Sciences (2023), TechTrends, DOI: 10.1007/s11528-023-00875-5 | View › Richards G.D., Jabbour R.S., Guipert G., Defleur A. Neanderthal child’s maxilla from Baume Moula-Guercy (Soyons, Ardèche, France) (2023), Anatomical Record, 306 (10), pp. 2484 - 2513 DOI: 10.1002/ar.25218 | View › Richards G.D., Jabbour R.S., Guipert G., Defleur A. Endocranial anatomy of the Guercy 1 early Neanderthal from Baume Moula-Guercy (Soyons, Ardèche, France) (2023), Anatomical Record, 306 (3), pp. 564 - 593 DOI: 10.1002/ar.25118 | View › Cai L., Al Turkestani N., Cevidanes L., Bianchi J., Gurgel M., Najarian K., Soroushmehr R. Integrative Risk Predictors of Temporomandibular Joint Osteoarthritis Progression (2023), Progress in Biomedical Optics and Imaging — Proceedings of SPIE, 12464, art. no. 124641N DOI: 10.1117/12.2651940 | View › Chen L.-C., Chen Y.-J., Lin H.-A., Chien W.-C., Tsai K.-J., Chung C.-H., Wang J.-Y., Chen C.-C., Liao N.-S., Shih C.-T., Lin Y.-Y., Huang C.-N., Ojcius D.M., Huang K.-Y., Lin H.-C. Inactivation of mitochondrial pyruvate carrier promotes NLRP3 inflammasome activation and gout development via metabolic reprogramming (2023), Immunology, 169 (3), pp. 271 - 291 DOI: 10.1111/imm.13628 | View › Suh H., Garnett B.S., Mahood K., Boyd R.L., Oh H. Short-term stability of anterior open bite treatment with clear aligners in adults (2023), American Journal of Orthodontics and Dentofacial Orthopedics DOI: 10.1016/j.ajodo.2023.05.026 | View ›

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Research and Scholarship

Khan J., Singer S.R., Young A., Tanaiutchawoot N., Kalladka M., Mupparapu M. Pathogenesis and Differential Diagnosis of Temporomandibular Joint Disorders (2023), Dental Clinics of North America, 67 (2), pp. 259 - 280 DOI: 10.1016/j.cden.2022.10.001 | View › Sharab L., Sonkar J., Thomas P.M., Prasannakumar P., Guha U., Leventer M., Vazouras K., Cappelli D. Reshaping dental faculty development using collective healthcare experiences (2023), Journal of Dental Education, 87 (9), pp. 1234 - 1241 DOI: 10.1002/jdd.13286 | View › Ng W.N.I., Kalimuthu S., Law C.O.K., Lee A.H.C., Lau T.C.K., Leung Y.Y., Cheung G.S.P., Neelakantan P. Intracellular bacterial eradication using a novel peptide in vitro (2023), International Endodontic Journal, 56 (11), pp. 1360 - 1372 DOI: 10.1111/iej.13965 | View › Mann A.E., O’Connell L.M., Osagie E., Akhigbe P., Obuekwe O., Omoigberale A., Kelly C., Coker M.O., Richards V.P. Impact of HIV on the Oral Microbiome of Children Living in Sub-Saharan Africa, Determined by Using an rpoC Gene Fragment Metataxonomic Approach (2023), Microbiology Spectrum, 11 (4) DOI: 10.1128/ spectrum.00871-23 | View › Chávez E.M. Oral health issues of late Baby Boomers (1956–1964) (2023), Special Care in Dentistry, 43 (3), pp. 320 327 DOI: 10.1111/scd.12848 | View › Coutinho Almeida-da-Silva C.L., Cabido L.F., Chin W.-C., Wang G., Ojcius D.M., Li C. Interactions between silica and titanium nanoparticles and oral and gastrointestinal epithelia: Consequences for inflammatory diseases and cancer (2023), Heliyon, 9 (3), art. no. e14022 DOI: 10.1016/j.heliyon.2023. e14022 | View › Peres Lima F.G.G., Rios L.G.C., Bianchi J., Gonçalves J.R., Paranhos L.R., Vieira W.A., Zanetta-Barbosa D. Complications of total temporomandibular joint replacement: a systematic review and meta-analysis (2023), International Journal of Oral and Maxillofacial Surgery, 52 (5), pp. 584 - 594 DOI: 10.1016/j. ijom.2022.10.009 | View › Salmanzadeh H., Poojari A., Rabiee A., Zeitlin B.D., Halliwell R.F. Neuropharmacology of human TERA2.cl.SP12 stem cell-derived neurons in ultra-long-term culture for antiseizure drug discovery (2023), Frontiers in Neuroscience, 17, art. no. 1182720 DOI: 10.3389/ fnins.2023.1182720 | View › O’Toole S., Moazzez R., Wojewodka G., Zeki S., Jafari J., Hope K., Brand A., Hoare Z., Scott S., Doungsong K., Ezeofor V., Edwards R.T., Drakatos P., Steier J. Single-centre, single-blinded, randomised, parallel group, feasibility study protocol investigating if mandibular advancement device treatment for obstructive sleep apnoea can reduce nocturnal gastro-oesophageal reflux (MAD-Reflux trial) (2023), BMJ Open, 13 (8), art. no. e076661 DOI: 10.1136/bmjopen-2023-076661 | View › Thor D., Xiao N., Zheng M. Reorganizing assessment questions to provide additional information on student understanding of specific course content (2023), Journal of Dental Education DOI: 10.1002/jdd.13349 | View ›

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Research and Scholarship

Huang C.-H., Yu S., Chou C., Wang T.-F. The Information-Motivation-Behavioral Skills Model: An Examination of Snacking-Avoidance Behavior Among Elementary Schoolchildren (2023), Child and Family Behavior Therapy, 45 (4), pp. 304 - 316 DOI: 10.1080/07317107.2023.2196644 | View › Gurgel M., Cevidanes L., Costa F., Pereira R., Cunali P., Bittencourt L., Ruellas A., Gonçalves J., Bianchi J., Chaves C. Three-dimensional comparison between the effects of mandibular advancement device and maxillomandibular advancement surgery on upper airway (2023), BMC Oral Health, 23 (1), art. no. 436 DOI: 10.1186/s12903023-03125-5 | View › Keener D.J., de Oliveira Ruellas A.C., Aliaga-Del Castillo A., Arriola-Guillén L.E., Bianchi J., Oh H., Gurgel M.L., Benavides E., Soki F., Rodríguez-Cárdenas Y.A., Ruíz-Mora G.A., Barkley M., Gebeck T., Jr., Hannapel E., McClatchey L.M., Pinzon M., Roberts C., Cevidanes L. Three-dimensional decision support system for treatment of canine impaction (2023), American Journal of Orthodontics and Dentofacial Orthopedics, 164 (4), pp. 491 - 504 DOI: 10.1016/j.ajodo.2023.02.016 | View › Weissheimer A., Lee R.J., Pham J., Tong H., Redmond W.R. Clinical Overview of InBrace Generation 2.0 (2023), Journal of Clinical Orthodontics, 57 (7), pp. 376 - 388 | View › Saghiri M.A., Vakhnovetsky A., Vakhnovetsky J. Scoping review of the relationship between xerostomia and voice quality (2023), European Archives of OtoRhino-Laryngology, 280 (7), pp. 3087 - 3095 DOI: 10.1007/s00405-023-07941-x | View › Saghiri M.A., Vakhnovetsky J., Samadi E., Napoli S., Samadi F., Conte M., Morgano S.M. Effects of Diabetes on Elemental Levels and Nanostructure of Root Canal Dentin (2023), Journal of Endodontics, 49 (9), pp. 1169 - 1175 DOI: 10.1016/j.joen.2023.07.002 | View › Verdugo J., Laughter L., Chambers D.W. Shared decision-making in scaling and root planing (2023), European Journal of Dental Education DOI: 10.1111/eje.12935 | View › Wang B.-Y., Burgardt G., Parthasarathy K., Ho D.K., Weltman R.L., Tribble G.D., Hong J., Cron S., Xie H. Influences of race/ethnicity in periodontal treatment response and bacterial distribution, a cohort pilot study (2023), Frontiers in Oral Health, 4, art. no. 1212728 DOI: 10.3389/froh.2023.1212728 | View › Sadowsky S.J. A Call for Innovation (2023), International Journal of Oral and Maxillofacial Implants, 38 (4), pp. 638 638 DOI: 10.11607/JOMI.10232 | View › Takei M., Takizawa K., Ozasa K., Nishikubo S., Young A., Noma N. Chronic osteomyelitis mimicking a temporomandibular disorder: a case report of two cases (2023), Quintessence International, 54 (1), pp. 44 - 52 DOI: 10.3290/j.qi.b3479985 | View ›

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Hilmi A., Patel S., Mirza K., Galicia J.C. Efficacy of imaging techniques for the diagnosis of apical periodontitis: A systematic review (2023), International Endodontic Journal, 56 (S3), pp. 326 - 339 DOI: 10.1111/iej.13921 | View › Elbarbary M., Goldberg M., Tenenbaum H.C., Lam D.K., Freeman B.V., Pustaka D.J., Mock D., Beyene J., Azarpazhooh A. Assessment of Concordance between Chairside Ultrasonography and Digital Palpation in Detecting Myofascial Trigger Points in Masticatory Myofascial Pain Syndrome (2023), Journal of Endodontics, 49 (2), pp. 129 136 DOI: 10.1016/j.joen.2022.11.013 | View › Zeitlin B.D. A flash of inspiration: Enhancing dental student drug recognition (2023), Journal of Dental Education DOI: 10.1002/jdd.13370 | View › Alzoubi F., Wong A. Fixed prosthetic rehabilitation of a patient with Papillon-Lefevre syndrome supported by a Quad Zygoma Approach: A clinical report (2023), Special Care in Dentistry, 43 (2), pp. 240 - 249 DOI: 10.1111/scd.12750 | View › Chan C.Y., Vishwanath V., Cheung H.Y., Cheng Y.T.J., Ki K., Airis Mok H.M., Pudipeddi A., Lee A.H.C., Cheung G.S.P., Neelakantan P. Tissue Stabilization, Bacterial Adhesion, and Stem Cell Viability in Trans-cinnamaldehyde-conditioned Dentin (2023), Journal of Endodontics DOI: 10.1016/j.joen.2023.09.011 | View › Miranda F., Choudhari V., Barone S., Anchling L., Hutin N., Gurgel M., Al Turkestani N., Yatabe M., Bianchi J., Aliaga-Del Castillo A., Zupelari-Gonçalves P., Edwards S., Garib D., Cevidanes L., Prieto J. Interpretable artificial intelligence for classification of alveolar bone defect in patients with cleft lip and palate (2023), Scientific Reports, 13 (1), art. no. 15861 DOI: 10.1038/s41598-023-43125-7 | View › Hardin L.T., Vang D., Thor D., Han X., Mashkoor F., Alpagot T., Ojcius D.M., Xiao N. Cigarette smoking exposure disrupts the regenerative potential of dental pulp stem cells (2023), Tobacco Induced Diseases, 21, art. no. 168125 DOI: 10.18332/tid/168125 | View › Quilici G., Tolarova M.M., Quilici M., Quilici D.L. Dental treatment of patients with prune belly syndrome (2023), Special Care in Dentistry, 43 (1), pp. 67 - 72 DOI: 10.1111/scd.12728 | View › Saghiri M.A., Vakhnovetsky J., Vakhnovetsky A., Samadi E., Samadi F. Volume and Power of Expansion of Novel Polyurethane-based Sealers (2023), Journal of Endodontics, 49 (8), pp.

1020 - 1026 DOI: 10.1016/j.joen.2023.05.019 | View › Khoshkhou H., Hasheminasab M., Goudarzi Pour D., Jamali R., Morshedzadeh Tehrani G., Moslemi N. Multiple maxillary periodontal abscesses as a manifestation of post-coronavirus disease 2019 mucormycosis: a case report (2023), Journal of Medical Case Reports, 17 (1), art. no. 74 DOI: 10.1186/s13256-023-03792-6 | View ›

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Research and Scholarship

Abdolmaleki A., Zare S., Saghiri M.A. Synthesis and characterization of biodegradable poly(ester-imide) nanocomposites with L-alanine, curcumin, and modified rGO (2023), Polymers for Advanced Technologies, 34 (8), pp. 2674 - 2683 DOI: 10.1002/ pat.6081 | View › Saghiri M.A., Amanabi M., Vakhnovetsky J., Amini S.B., Samadi E. Effects of brushing duration on the efficacy of dental plaque removal: An in vitro study (2023), International Journal of Dental Hygiene, 21 (3), pp. 618 - 623 DOI: 10.1111/idh.12679 | View › Fears N.E., Templin T.N., Sherrod G.M., Bugnariu N.L., Patterson R.M., Miller H.L. Autistic Children Use Less Efficient Goal-Directed Whole Body Movements Compared to Neurotypical Development (2023), Journal of Autism and Developmental Disorders, 53 (7), pp. 2806 - 2817 DOI: 10.1007/s10803-022-05523-0 | View › Baněčková M., Cox D. Top 10 Basaloid Neoplasms of the Sinonasal Tract (2023), Head and Neck Pathology, 17 (1), pp. 16 32 DOI: 10.1007/s12105-022-01508-8 | View › Zeitlin B.D., Sadhak N.D. Attitudes of an international student cohort to the Quizlet study system employed in an advanced clinical health care review course (2023), Education and Information Technologies, 28 (4), pp. 3833 - 3857 DOI: 10.1007/s10639-022-11371-3 | View › Doubleday A.F., Horvath Z., Mara M.D., Sabato E., Zheng M. The dental education exchange: A multi-institutional faculty learning community (2023), Journal of Dental Education DOI: 10.1002/jdd.13366 | View › Yari A., Hasheminasab M., Fasih P., Nouralishahi A., Arianezhad S.M. The pattern of maxillofacial fractures associated with rollover accidents: A 7-year retrospective study (2023), Dental Traumatology DOI: 10.1111/edt.12900 | View › Davoodi N.S., Tayebi A., Rahimipour K., Zarei M., Mozaffari A., Mirzadeh M., Mousavi R., Bayat N. Efficacy of a mobile phone application for the improvement of oral hygiene of patients undergoing fixed orthodontic treatment: A randomized controlled clinical trial [Wirksamkeit einer Mobiltelefonanwendung zur Verbesserung der Mundhygiene von Patienten während einer kieferorthopädischen Behandlung mit festsitzenden Apparaturen: Eine randomisierte kontrollierte klinische Studie] (2023), Journal of Orofacial Orthopedics DOI: 10.1007/s00056-023-00492-0 | View › Lee K.C., Lim S.-W., Cho J.-H., Oh H., Hwang H.-S. Survival rates of mandibular fixed retainers: comparison of a tube-type retainer and conventional multistrand retainers: A prospective randomized clinical trial [Überlebensraten von festsitzenden Unterkieferretainern: Vergleich eines röhrchenförmigen Retainers und konventioneller Mehrstrangretainer: Eine prospektive, randomisierte klinische Studie] (2023), Journal of Orofacial Orthopedics DOI: 10.1007/s00056-023-004475 | View ›

insight

Research and Scholarship

Gillot M., Miranda F., Baquero B., Ruellas A., Gurgel M., Al Turkestani N., Anchling L., Hutin N., Biggs E., Yatabe M., Paniagua B., Fillion-Robin J.-C., Allemang D., Bianchi J., Cevidanes L., Prieto J.C. Automatic landmark identification in cone-beam computed tomography (2023), Orthodontics and Craniofacial Research, 26 (4), pp. 560 - 567 DOI: 10.1111/ocr.12642 | View › Alzoubi F.M., Sabti M., Alsarraf E., Alshahrani F.A., Sadowsky S.J. Evaluation of two implant-supported fixed partial denture abutment designs: Influence on screw surface characteristics (2023), Journal of Prosthodontics DOI: 10.1111/jopr.13716 | View › Chambers D.W. Toward an operational definition of shared decision making: A conceptual analysis (2023), Journal of Evaluation in Clinical Practice, 29 (7), pp. 1061 - 1067 DOI: 10.1111/jep.13773 | View › Karimi A., Derakhshan S., Hasheminasab M., Kordi S. Fibrous dysplasia associated with peripheral giant cell granoluma in maxilla in a young patient, a case report of rare hybrid lesion (2023), Rare Tumors, 15 DOI: 10.1177/20363613231165883 | View ›