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A MESSAGE FROM amfAR
Good evening and welcome to amfAR London.
Having held successful events in many European cities over the past 40 years, we are delighted to be hosting our first-ever benefit gala here in London and deeply grateful to you for joining us tonight.
amfAR’s ties to the UK go back many years. Our Founding International Chairman was London-born Dame Elizabeth Taylor, whose passionate advocacy inspires us to this day. We work closely with HIV research teams in the UK and have awarded more than $2.5 million in grants to scientists at institutions such as Oxford University and University College London.
Our research investments over the years have contributed to the development of many of the drugs that are helping to keep millions of people alive. However, the impact of our research extends far beyond HIV. The scientific advancements it has driven have become a springboard for breakthroughs in cancer immunotherapy, neurological disorders, autoimmune diseases, and new responses to viral threats like COVID-19.
amfAR is building on this legacy of innovation and investing not only in the most promising paths toward an HIV cure but also in cross-disciplinary research that unlocks lifesaving discoveries for a wide range of diseases. By serving as a catalyst for bold biomedical research, amfAR ensures that every dollar invested has a ripple effect across global health, advancing further discoveries.
That’s why we’re here tonight. Events like amfAR London generate the vital resources that fuel our research and allow us to provide a critical lifeline to outstanding researchers in need of support.
Enjoy the evening—and thank you for your generosity.
T. Ryan Greenawalt
Kevin McClatchy Co-Chair of the Board Co-Chair of the Board
amfAR, The Foundation for AIDS Research, is one of the world’s leading nonprofit organizations dedicated to the support of AIDS research, HIV prevention, treatment education, and advocacy. Since 1985, amfAR has raised nearly $950 million in support of its programs and has awarded more than 3,800 grants to research teams worldwide.
T. Ryan Greenawalt
Kevin McClatchy Co-Chairs of the Board
Kevin Robert Frost Chief Executive Officer
In Memoriam Mathilde Krim, PhD Founding Chairman
Dame Elizabeth Taylor Founding International Chairman
Where Life Science Meets Investment
16-21 November 2025
KATE BECKINSALE
HELENA BONHAM CARTER
MICHAEL BONSOR
OLIVIA BUCKINGHAM
SABRINA DHOWRE ELBA
CYNTHIA ERIVO
LUKE EVANS
COLIN FIRTH
DAVID GLASSER
T. RYAN GREENAWALT
SARAH HARRIS
CHAIRS
ANU HINDUJA
LUCIEN LAVISCOUNT
MICHAEL LORBER
LUCA MAGGIORA
KEVIN MCCLATCHY
VIN ROBERTI
EMMA THOMPSON
ROBERT L. TRAYNHAM II
HARRY WELLER
PHILL WILSON
GRAND PHILANTHROPISTS
DEMETRIOS BRADSHAW
JAMIE GOGUEN
OGULCAN YILDIZ
PATRONS
LODHA PARTNERS
RYAN DONNELL SMITH
PHILANTHROPISTS
LADY MONIKA BACARDI
MARIA BOGDANOVICH
JULIA BURIAK
MARIA GALKINA
LUKE LEE
MANISH MALHOTRA
MARINA PRIYOMOVA
LUNA WIELGOMAS
DIANA YEVDOKIMOVA
List as of October 13, 2025
THE DATE FRIDAY NOVEMBER 21 IN PARTNERSHIP WITH HOSTED AT FOR FURTHER INFORMATION IN COLLABORATION WITH
JOELY RICHARDSON is a double Golden Globe-nominated actor for her work in television. She costarred for six seasons on Ryan Murphy’s Nip/Tuck, appeared in The Tudors, and lately in the Sandman franchise and on Downton Abbey. She can also be seen in Guy Ritchie’s The Gentlemen, seasons 1 and 2, which is currently filming.
Joely started off her career in theatre (Royal Shakespeare Company, West End, Old Vic) mixed with independent films and the studio classic, Disney’s 101 Dalmatians. Since then, she has worked extensively in America and England in both theatre and film.
At the 2014 amfAR New York Gala, Joely and her mother, Vanessa Redgrave, were honored with amfAR’s Award of Courage. Her sister, the late Natasha Richardson, served on the amfAR Board of Trustees.
DAME TRACEY EMIN
AWARD OF INSPIRATION
TRACEY EMIN’S art is one of disclosure, using her life events as inspiration for works ranging from painting, neon, drawing, video, and installation to photography, needlework, and sculpture. Emin reveals her hopes, humiliations, failures, and successes in candid and, at times, excoriating work. Emin’s art has an immediacy and often sexually provocative attitude that firmly locates her oeuvre within the tradition of feminist discourse. Her paintings, monoprints, and drawings explore complex personal states and ideas of self-representation through manifestly expressionist styles and themes.
Tracey Emin was born in London in 1963 and studied at Maidstone College of Art and the Royal College of Art, London. She represented Great Britain at the Venice Biennale in 2007 and was elected a Royal Academician in the same year. In 2011, Emin became the Professor of Drawing at the Royal Academy of Arts, London. In June 2024, King Charles III appointed her Dame Commander of the Most Excellent Order of the British Empire for her contributions to the visual arts.
Emin lives and works between London, the South of France, and Margate. Her next solo exhibition will be held at Tate Modern in Spring 2026.
NATASHA POONAWALLA is Executive Director of Serum Institute of India, one of the world’s largest vaccine manufacturers, and Chairperson of Serum Life Sciences, driving global vaccine development and pandemic preparedness.
She also leads strategy across the Cyrus Poonawalla Group and serves as Chairperson of the Villoo Poonawalla Foundation, which has transformed millions of lives in India through education, healthcare, sanitation, and clean water initiatives. In addition, she is Director of the Poonawalla Science Park in the Netherlands and holds leadership roles with the British Asian Trust.
Building on her work in public health and philanthropy, Natasha is the Founder of Phinity, a pioneering venture creating a new global ecosystem at the intersection of wellness, culture, and sustainability. A patron of the arts and advocate for women’s leadership, she holds an MSc from the London School of Economics and is recognized worldwide for her influence across health, entrepreneurship, and cultural innovation.
NATASHA POONAWALLA
PHILANTHROPIC LEADERSHIP AWARD
J ESS GLYNNE
PERFORMER
JESS GLYNNE is a London-born singersongwriter who made history by becoming the first and only British female solo artist to score seven number ones on the UK Singles Chart—among them “I’ll Be There,” “Hold My Hand,” and “Don’t Be So Hard on Yourself.”
Jess rose to prominence in 2013 as a featured artist on the multi-platinum singles “Rather Be” by Clean Bandit and “My Love” by Route 94, both of which soared to UK number one in the charts. Since then, Jess Glynne has earned a GRAMMY Award, three Ivor Novello Awards, and nine BRIT Award nominations. With her first two chart-topping albums I Cry When I Laugh and Always In Between becoming Platinum bestsellers, Jess was named on Forbes’ notorious “30 Under 30” in 2019 following her sold-out world tour.
After taking a break from music, Jess signed with Jay-Z’s Roc Nation, secured a brand new record deal with music giant EMI, and went full steam ahead into her new body of work. Jess Glynne has just released her third studio album JESS, already featuring in the Official Top Ten Charts. A hugely proud piece of work and six years in the making, JESS is representative of where she has evolved to musically and in life since the release of her previous album. Written between London and LA, the 15-track selftitled album is penned with a deep sense of empowerment through Jess’s intimate songwriting style, featuring soulful ballads and the quintessential pop anthems that have earned Jess the title of one of music’s most successful artists.
Adding to her accolades, in April 2024 Jess received the hugely prestigious BRIT Billion Award for achieving over one billion streams in the UK, following in the footsteps of previous winners Ed Sheeran, Billie Eilish, and Lana Del Rey.
GRACE JONES is a Jamaican-American singer, model, and actress. She began her career as a model, quickly gaining recognition for her striking presence and unique style. Jones became a muse for Andy Warhol, who photographed her extensively. During this period, she was a regular at New York City’s Studio 54, immersing herself in the vibrant cultural scene of the era.
In 1977, Jones secured a record deal with Island Records, launching a series of dance-club hits that established her musical reputation. Her singles frequently charted on Billboard’s Hot Dance Club Play and Hot Dance Airplay charts, with the 1981 hit “Pull Up to the Bumper” spending seven weeks at #2 on the U.S. dance chart. Grace Jones also found mainstream success in Europe, achieving several Top 40 entries on the UK Singles Chart. Her most notable albums include Warm Leatherette, Nightclubbing, and Slave to the Rhythm. In addition to “Pull Up to the Bumper,” her biggest hits are “I’ve Seen That Face Before (Libertango),” “Private Life,” “Slave to the Rhythm,” and “I’m Not Perfect (But I’m Perfect for You).”
Jones expanded her career into acting in the 1970s. Her mainstream debut came in 1984 with the fantasy/action film Conan the Destroyer alongside Arnold Schwarzenegger, followed by prominent roles in the 1985 James Bond movie A View to a Kill and the 1986 film Vamp. In 1992, Jones both acted in and contributed a song to Boomerang with Eddie Murphy. Her later acting work includes an appearance in Wolf Girl alongside Tim Curry in 2001.
Jones released the 2008 album Hurricane (Wall of Sound/PIAS Records), earning positive reviews. She supported the album with a 2008–2009 concert tour and performances at the Secret Garden Party and Latitude Festival. In 2011, Jones collaborated with Brigitte Fontaine on two tracks from Fontaine’s album L’un n’empêche pas l’autre and performed at the opening ceremony of the 61st FIFA Congress. Notably, she delivered a memorable performance during Queen Elizabeth II’s 60th Jubilee, where she sang while performing 10 minutes of hula hooping.
Jones published her memoir, I’ll Never Write My Memoirs, in 2015. In 2018, the documentary Bloodlight and Bani, directed by Sophie Fiennes, was released.
The singer is currently finishing work on her next album.
GRACE JONES
CALENDAR OF EVENTS
Renowned worldwide, amfAR’s galas are the largest source of funding for the Foundation’s lifesaving research.
By purchasing tickets or tables, or simply making a donation, you are directly advancing the fight to end AIDS.
amfAR LAS VEGAS NOV 21, 2025
amfAR PALM BEACH MARCH 2026
amfAR GALA CANNES MAY 21, 2026
If you are interested in attending or learning more about our upcoming events, please contact us at events@amfar.org
AUCTION CATALOGUE
LIVE AUCTION CONDUCTED BY SIMON DE PURY
EVENT PRODUCED BY EMANUELA SANTI/ EVENT REPUBLIC STUDIO
Full terms and conditions can be found at the end of the auction catalogue section.
A HUNTSMAN MASTERCLASS: CREATE YOUR OWN BESPOKE SUIT
Have you ever wondered what sets a Huntsman suit apart from any other in the world? An address synonymous with the highest level of quality and craftsmanship, Huntsman has been creating the world’s finest handcrafted clothes for over 175 years, a legacy of excellence unrivalled on Savile Row. This extraordinary, fully immersive experience offers the rare opportunity to take part in the making of your very own bespoke garment, a piece to cherish for a lifetime.
Your journey begins with a private appointment in the comfort of the Huntsman Clubroom at 11 Savile Row. Here, you will meet the team, explore our library of rare and luxurious cloths, and select the fabric that will bring your vision to life. Your measurements will be taken, marking the beginning of an unforgettable experience in the art of bespoke tailoring.
Working alongside Huntsman’s Head Cutter in our iconic Cutting Theatre, you will help draft and cut your own bespoke pattern, witnessing first-hand the precision and artistry that define Savile Row craftsmanship. These traditional practices, perfected over more than a century, offer a rare glimpse into the living history of tailoring at its finest.
You will then join Campbell Carey for lunch at a distinguished Mayfair establishment, following a time-honoured tradition amongst Head Cutters, before returning to Huntsman to strike and cut your chosen cloth. Here, you will practise your ‘rock-ofeye’, the intuitive skill mastered by tailors and celebrated in bespoke lore, as you shape the beginnings of your own sartorial legacy.
Once complete, your garment will be entrusted to our team of expert tailors, who will devote over 80 hours of meticulous handwork, with as many as 15 pairs of skilled hands contributing to its creation, among them, your own! The day concludes with a well-earned champagne tasting in the Clubroom, hosted by our partners at BillecartSalmon, a fitting toast to your journey at the heart of Savile Row craftsmanship.
Your finished suit will be more than a wardrobe addition; it will represent your part in Huntsman’s enduring story of excellence, a garment destined to last a lifetime. This experience includes:
• A Two-Piece Bespoke Suit from Huntsman
• Private Appointment and Cloth Selection at 11 Savile Row
• Drafting & Marking of Your Bespoke Pattern alongside Head Cutter Campbell Carey
• Lunch in Mayfair with Campbell Carey
• Striking and Cutting of Your Chosen Cloth
• Champagne Tasting in the Huntsman Clubroom, hosted by Billecart-Salmon
Courtesy of Huntsman (@huntsmansavilerow)
Experience must be booked within 12 months of auction date and is subject to availability. Appointments are available Monday to Friday, during Huntsman’s standard opening hours. The prize is non-transferable, non-exchangeable, and holds no cash value. It may not be resold, transferred, or used for any commercial purpose. Further auction terms and conditions can be found at the end of the auction catalogue section.
AROUND THE WORLD WITH ROSEWOOD
If you enjoy travel and luxury, this is the package of your dreams. You and a guest will escape on a magical journey to four of Rosewood’s most exclusive properties spanning four continents.
ROSEWOOD MAYAKOBA
Located in the heart of Mexico’s Riviera Maya and surrounded by verdant emerald jungle, Rosewood Mayakoba lies along a pristine stretch of Caribbean beach and inhabits a private world of rare luxury and refined beauty.
• Five (5) night stay in a four-bedroom villa
• Includes daily breakfast for two (2)
• Includes round-trip airport transfers
• Valid through October 30, 2026; blackout dates: Easter, Thanksgiving, Festive Season
ROSEWOOD MUNICH
Rosewood Munich celebrates the grandeur and vibrant culture of its extraordinary city. Housed in two beautifully restored landmark buildings, the property balances a convivial, inviting spirit with refined touches such as luxurious furnishings, bespoke service, and curated artwork.
• Five (5) night stay for two (2) in the Premier Suite
• Includes daily breakfast for two (2)
• Airport transfers not included
• Three-course dinner with wine pairing in Brasserie Cuvilliés restaurant for two (2)
• Voucher subject to availability; blackout dates apply
Courtesy of Rosewood Mayakoba, Rosewood Munich, Rosewood Hong Kong, Rosewood Le Guanahani St. Barth
ROSEWOOD HONG KONG
Rising majestically over Victoria Harbour in Kowloon, Rosewood Hong Kong is the epicenter of the new Victoria Dockside arts, culture, and luxury retail district. Harbour Corner Suite boasts expansive views of the majestic Victoria Harbour and Hong Kong Island. Residential luxury is revealed in the spacious corner layout, with collectable, curated details, enhanced by personalised butler service and Manor Club access.
• Five (5) night stay for two (2) in a Harbour Corner Suite
• Access to Manor Club
• Valid through December 31, 2026; subject to availability; blackout dates apply
ROSEWOOD LE GUANAHANI ST. BARTH
Nestled on a private 18-acre peninsula between lagoon and ocean, this vibrant nature reserve blends effortless elegance, refined adventure, and joie de vivre. Rosewood Le Guanahani St. Barth is a haven of casual luxury, comfort, and elegance. Vibrantly hued guest cottages are scattered along garden paths that wind through lush bougainvillea, hibiscus, and palms beside the sweeping beaches and reef-protected lagoon.
• Five (5) night stay for two (2) in an Ocean View Suite
• Includes daily breakfast for two (2) at Beach House St. Barth
• Includes round-trip airport transfers
• Valid April 12 – July 31, 2026. Subject to availability; blackout dates apply
GLENN SPIRO JEWELRY: THE LUMA EARRING
Gold weight: 9.00 grams
Hyceram weight: 16.23 grams
Total weight: 26.20 grams
A striking pair blending innovative materials with timeless elegance. Crafted in Hyceram Luminex and 18K red gold, the earrings are elegantly set with two pearshaped Kyanites, totaling 4.83 carats.
The design is part of a limited-edition collection, with this pair numbered 5 in the exclusive series.
Known to collectors and aficionados, Glenn Spiro Jewelry, headed by master jeweler Glenn and his son Joe, has become one of the most renowned private jewelry houses in the world.
In their appointment-only London atelier, the former studio of fashion designer Sir Norman Hartnell, Glenn Spiro Jewelry combines exquisitely detailed settings with an eye-watering selection of unique stones. A couture piece of theirs can be years in the making and their technical mastery has gained a cult following of collectors. Glenn Spiro is renowned as having an unconventional approach to the Haute Joaillerie world, but it’s the risks they take in a realm dominated by old luxury marques and multigenerational businesses that truly set them apart. The house has a nonconformist attitude to precious gemstones—they attempt the impossible and dream up imaginative designs that have never been done before. The gems are the elusive varieties that jewelers dream about, sometimes for decades, until that sought-after stone with a spellbinding hue, intensity, uniformity of color, and inner sparkle finally surfaces.
The resulting jewelry turns heads for all the right reasons, commanding attention for its originality and the confidence that it embodies.
“We don’t make what people want; we make what we love—and if they love it, then great,” Glenn says. “If not, we’ll keep it in the safe until the right person walks through the door.”
Courtesy of (@glennspirojewels)
EXCLUSIVE amfAR GALA CANNES EXPERIENCE FOR
TWO HÔTEL DU CAP-EDEN-ROC | MAY 18–22, 2026
Sun, sea, and the stunning coastline of Cap d’Antibes await you with this exclusive VIP package for two at amfAR Gala Cannes 2026, featuring a five-night stay at the luxurious Hôtel du Cap-Eden-Roc, which hosts the event on its grounds.
Launched in 1993 by amfAR Founding International Chairman Dame Elizabeth Taylor, amfAR Gala Cannes has evolved into the Foundation’s premier benefit gala and a must-attend event during the Cannes International Film Festival. Year after year, the black-tie event features unforgettable musical performances and attracts notable guests from the worlds of film, fashion, business, philanthropy, sports, and the arts. Icons such as Cher, Tom Cruise, Leonardo DiCaprio, Sir Tom Jones, Spike Lee, Madonna, Helen Mirren, Demi Moore, and Michelle Yeoh have all graced the red carpet at amfAR Gala Cannes.
You and a guest will enjoy five nights at the legendary Hôtel du Cap-Eden-Roc, an architectural gem recently renovated by Brazilian architect Patricia Anastassiadis. A haven on the Riviera for over 150 years, everyone from Greta Garbo and Ella Fitzgerald to Marc Chagall and Picasso have walked its resplendent paths and rose gardens. Nestled atop a craggy cliffside, the grounds offer timeless pleasures and relaxation in total privacy—a saltwater infinity pool with stunning views of the Mediterranean, seaside cabanas, a spa, and tennis courts. A unisex hair salon, complete with beauty and grooming treatments, has everything you need to get ready for amfAR Gala Cannes on Thursday, May 21.
In your room, indulge in peaceful quiet and quaint elegance with classic French country touches. The hotel’s many restaurants offer cuisine crafted by Executive Chef Sébastien Broda, who takes a contemporary approach to Mediterranean and Provençal flavors.
The hotel is closed to the public during the Cannes International Film Festival, so this experience is an ultra-exclusive and unique indulgence made possible through amfAR.
Experience the sparkling Côte d’Azur as the global community comes together to celebrate cinema and raise funds for amfAR’s lifesaving research.
PACKAGE INCLUDES:
• Accommodations for two (2) at Hôtel du Cap-Eden-Roc for five (5) nights
• Two (2) Supporter tickets for amfAR Gala Cannes
Available only for May 18-22, 2026. Airport transfers included; airfare not included. Incidentals not included. Exact itinerary subject to final scheduling. Experience cannot be transferred or resold. Further auction terms and conditions can be found at the end of the auction catalogue section.
AUCTION RULES AND CONDITIONS
1. amfAR will accept advance bids on all auction items until 12:00 p.m., British Summer Time, Friday, October 17, 2025.
2. All bids are legally binding and cannot be withdrawn. By participating in this auction, you irrevocably agree: (1) to submit all claims, disputes, suits, actions, or other proceedings arising out of or related to this auction, to the exclusive jurisdiction of American Arbitration Association (“AAA”) with the place of arbitration to be designated as New York County, New York; (2) that any hearing conducted as part of the AAA proceeding shall be done via video or telephone as permitted by the AAA Commercial Arbitration Rules; and (3) to accept any papers, notices, or process necessary or proper for the initiation or continuation of arbitration under these terms and conditions, for any court action in connection therewith, or for the entry of judgment on any award made under these terms and conditions to be served by electronic mail at the email address provided to amfAR by You or Your agent. Failure to accept service and/or appear in the arbitration proceedings shall be deemed a default by You, and shall result in a default judgment. The arbitrators shall have no power to vary these terms and conditions or grant any extension of time for the payment of any monies payable by any party in accordance herewith, or otherwise limit the obligations of the parties hereunder, and shall be limited to the interpretation and enforcement of the obligations of the parties hereunder. Any awards or judgments issued via arbitration shall be submitted to any court of competent jurisdiction for enforcement. The prevailing party shall be entitled to recovery of reasonable attorney’s fees and associated costs.
3. Payments made by credit card are subject to a 3% surcharge.
4. The highest bidder as determined by amfAR at the close of the auction lot will win the item or service.
5. Every effort has been made to describe auction items accurately. However, all items are sold “as is” and “where is” without warranty or representation of any kind as to accuracy of description, authenticity, value, or fitness for any purpose. By participating in the auction, each bidder recognizes and agrees that amfAR is not liable for any occurrence stemming from the use of the auctioned items or services. All sales are final, and refunds and exchanges are not allowed.
6. Winning bidders should contact the Special Events Team at auction@amfar.org by 5:00 p.m., Monday, October 20, 2025, and make payment to amfAR by Monday, October 27, 2025. amfAR accepts American Express, Mastercard, Visa, and Discover. amfAR will also accept checks made out in USD, a wire transfer of funds, or cryptocurrency as noted on the following page. amfAR’s permanent office may be reached at +1 (212) 806-1600.
7. Successful bidders will be responsible for applicable taxes, storage fees, and any outof-town shipping or delivery costs, even if arranged by amfAR, unless otherwise noted.
8. All auctioned items are subject to the terms and conditions stipulated by the donors. Purchases that are subject to future fulfillment, such as travel or entertainment items, depend on the schedules of both the purchaser and the donors of the items. amfAR is not responsible if mutually agreeable times and locations cannot be reached.
9. No refund can be given for purchases/packages not fulfilled within the time period reflected in auction lot descriptions, where applicable.
10. All items have been acquired by amfAR for the auction. These items are sold by amfAR and not by the donors.
11. A small portion of the proceeds from the sale of certain items presented herein may be used by amfAR to cover acquisition and logistical costs associated with the procurement and sale of the item. Additional information is available to interested bidders and purchasers by contacting amfAR Special Events at auction@amfar.org.
12. amfAR is not liable for any delays or non-performance in the fulfillment of auction lots due to government-imposed measures or unanticipated circumstances or conditions related to COVID-19. Where reasonably possible, amfAR will work with winning bidders to fulfill purchased lots, subject to delays in transportation, travel, schedules, and other logistics beyond amfAR’s reasonable control.
TERMS AND CONDITIONS FOR CRYPTOCURRENCY
PLEASE NOTE THAT BY REGISTERING TO BID YOU AGREE TO THE FOLLOWING:
You are bidding as principal and not on behalf of anyone else.
Payments made in cryptocurrency must equal the amount of the hammer price in pounds at the time the winning bid is accepted, plus 5% of the total purchase to cover processing and liquidation fees.
Payments in cryptocurrency must be made here: amfar.org/crypto
Enter your donor information and the amount of your payment in pounds at the time of purchase, plus 5% of the total purchase to cover processing and liquidation fees. Once you have made your purchase, please email us at crypto@amfar.org so that we may identify and acknowledge your payment. Please note that any payments made in cryptocurrency are strictly non-refundable.
If you are the successful bidder, you agree to provide us with all information and documentation we request in order to verify your identity and to confirm that the payment received was made by you.
If you are the final bidder on any auction lot, amfAR will reach out to you prior to sending an invoice to confirm you still intend to pay with cryptocurrency.
amfAR only accepts cryptocurrencies and tokens supported by the Gemini Exchange; you can find a list at amfar.org/accepted-crypto.
Please email us at crypto@amfar.org with questions.
Making an Impact
For 40 years, amfAR has funded research that has revolutionized the treatment and prevention of HIV, benefited diseases beyond the virus, and forged a path toward a cure that could end AIDS once and for all. These advances would not be possible without the generosity of supporters like you. Here are some of the ways your generosity has helped make an impact.
• Lifesaving treatment: amfAR’s research has contributed to the development of four of the six main classes of antiretroviral drugs in use today.
• HIV transmission: amfAR’s first international research grant, awarded in 1987, supported a landmark study in Kenya that showed that HIV transmission can occur from females to males, and vice versa.
• CCR5, a key protein: amfAR funded research showing that HIV almost always requires a protein called CCR5 to enter and infect cells. This breakthrough led to the development of the antiHIV drug maraviroc, which blocks CCR5.
• Curing HIV: The discovery of CCR5 paved the way to the first case of an HIV cure in 2008. This was made possible by a stem cell transplant using donor cells lacking the CCR5 gene. Several people have since been cured using the same method.
• Mother-to-child HIV transmission: amfAR pioneered research that led to the use of antiretroviral drugs to block mother-to-child HIV transmission. As a result, this mode of transmission has been all but eliminated in many parts of the world.
• Other medical breakthroughs: AIDS research is providing insights into a range of diseases, their causes, and their treatment. Better diagnostic methods, therapies to restore the immune system, newer preventive antibiotics and drugs, and new treatments for infectious diseases and cancer were all developed in the course of AIDS research.
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