One Nucleus Update 1

Directory 2012

NEB solutions

OEM and customized products

NEBsolutions – " -BTUJOH 1BSUOFSTIJQ 1BSUOFS XJUI /&# GPS ZPVS 0&. BOE DVTUPN SFBHFOU OFFET &YQFSJFODF B TVQQPSUJWF DPMMBCPSBUJPO DPNCJOFE XJUI B GBTU BOE SFMJBCMF DPODFQU UP DPNNFSDJBMJ[BUJPO EFWFMPQNFOU BOE NBOVGBDUVSJOH TFSWJDF -FWFSBHF PVS ZFBST PG FYQFSJFODF JO UIF BSFBT PG SFBHFOU EFTJHO BOE EFWFMPQNFOU GFSNFOUBUJPO BOE QSPDFTT EFWFMPQNFOU FYUFOTJWF RVBMJUZ DPOUSPM BOE WBMJEBUJPO SJTL NJUJHBUJPO BOE TPVOE TVQQMZ DIBJO NBOBHFNFOU

Choose NEB as your custom solutions provider and experience: t 3BQJE RVPUF UVSOBSPVOE t $VTUPN QSPEVDU JO BT MJUUMF BT XFFLT t 3BQJE BOE GMFYJCMF TDBMF VQ t 'BTU UVSOBSPVOE PO TQFDJBM GPSNVMBUJPOT MBCFMJOH BOE QBDLBHJOH GPSNBUT t %FQFOEBCMF DPOTJTUFOU TVQQMZ t )JHIMZ EFWFMPQFE SJTL NJUJHBUJPO QSPDFEVSFT t 3FHVMBS BVEJUT PG NBOVGBDUVSJOH DBQBCJMJUJFT

/FX &OHMBOE #JPMBCT BOE .PMFDVMBS %JBHOPTUJDT Since 1995, New England Biolabs has been a strategic partner serving the needs of Molecular Diagnostics customers – from early-stage platform development through regulatory approval, with a commitment to long-term technical support. With over 15 years of experience in supplying the Molecular Diagnostics field with validated critical raw materials, NEB works closely with its customers to ensure reagent optimization and quality assurance within a variety of diagnostic formats, including flow cells, on polymer beads, as lyophilized product, in multi-well plate formats, with nanoparticles, and customized assay devices.

Partner with NEB and take advantage of over 35 years of scientific expertise. Our broad scientific base has lead to the development of reagents for a wide range of applications, including: t .PMFDVMBS %JBHOPTUJDT t %/" 3/" 4FRVFODJOH t (FOF &YQSFTTJPO "OBMZTJT t %SVH %JTDPWFSZ %FWFMPQNFOU

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“NEB has been providing our company with high quality enzymes for several years. In that time, we have found that the quality of their products is only surpassed by their technical expertise and highly professional staff. They set the standard for quality products and customer service.� – Manager, genomics instrument and reagent supplier

8IBU EPFT /&#TPMVUJPOT NFBO GPS ZPV 3FTQPOTJWFOFTT

'MFYJCJMJUZ

4FSWJDF

$SFEJCJMJUZ

Experience rapid turnaround on quotes, on time delivery of your product, and immediate access to the broad scientific resources available from NEB.

Engage with our NEBsolutions team to quickly apply resources and deliver solutions when you need them.

Take advantage of our direct service and broad technical support liased through the NEBsolutions group.

Benefit from 20 years of experience in the development and supply of reagents for OEM customers, and over 35 years serving the life sciences.

Quality

Expertise

4DBMBCJMJUZ

$VTUPNJ[BUJPO

Depend on our unsurpassed product purity and lot-to-lot consistency to ensure that your product will perform how you want it, when you need it. Work directly with our NEBsolutions team to develop customer-defined QC assays and QA processes tailored to the needs of your application.

Collaborate directly with our R&D scientists who have extensive experience in a wide range of applications. Engage with our Production and Quality Teams in the development of supporting processes and documentation to meet your QA expectations.

Quickly achieve volume requirements by leveraging our gene expression expertise, as well as our state-of-the-art Fermentation and Scale Up Facilities.

Improve efficiency by relying on us to meet your product specifications, including formulations, quality controls, volumes, vials, private labeling and kitting capabilities.

Please contact us at CVTEFW!VL OFC DPN to start increasing your profits, benefitting from optimal production efficiency, and maximizing your commercial application potential.

www.neb.uk.com/solutions

Contents

Designed and produced by:

7. About One Nucleus 9. Welcome 10. One Nucleus Services 13. Member Benefits and Prices 14. To Sponsor One Nucleus 17. Partner Programme 18. Life Science Leadership Series 21. Genesis 22. Bench-to-Boardroom 23. Dates for your Diary 25. Purchasing Scheme 29. Facilities Management Services 30. Training Courses 33. Special Interest Groups 35. European Activities 36. Strategic Relations with Top US Clusters 39. One Nucleus Collaborations

Distinctive Publishing 6th Floor Aidan House Sunderland Road Gateshead NE8 3HU T: 0845 884 2385 www.distinctivepublishing.co.uk

Disclaimer Published by Distinctive Publishing on behalf of One Nucleus. While every effort has been made to ensure that the information in this document is accurate at the time of going to press, no liability for damage is accepted

by One Nuclues arising from any errors or omissions that may appear, however caused – or from any editorial alterations to submitted information.

The Editor reserves the right to edit or exclude entries. www.onenucleus.com

5

Now you really DO have a choice!

For the last 10 years, JAG EXPRESS has been expertly looking after the express courier and logistics requirements of Companies and individuals within the Bioresearch sector in and around Cambridge.

We have seen customers go from the initial research phase through to full production and beyond, with them calling on our differing services as their needs changed.

For much of this time, we have been frustrated seeing how other Courier Companies overcharge and overcomplicate the issue of handling Hazardous, Biohazard, Medical & Dry Ice shipments …

We have our own fully trained IATA Approved Dangerous Goods Specialist on site, meaning we can cut out the other middle men and offer you totally unbiased advice and practical help in moving hazardous and medical materials anywhere in the world … and we believe our in house systems and dedication to customer service mean that we can simplify the process for you and reduce your costs.

As an example – one of our existing customers is saving over £400 on each Dry Ice shipment they send abroad with us compared to their previous supplier!

But now you really do have a choice …

So whether you’re new to shipping either standard or hazardous materials, or experienced and just want to check out your options – why not contact us and try us out?

Customer feedback …

Our services include …

“What a pleasure to deal with a supplier who not only seems to care about our goods but actually shows an interest in our business ... you make us feel as if we are your best customer.”

• • •

• • • • • •

“Fantastic service! Jag has really found a way to ship our Dry Ice shipments around the world simply and on time ... and is saving us hundreds of pounds per shipment compared to our old supplier ...” “... your software is saving me several minutes on each shipment I send. It may not sound like a lot, but if I’m sending 10 or more in a single day the time saving really mounts up!”

“We were told by xxx that our shipment requirement was impossible. One quick call to Jag and it became not only possible, but achievable and under budget” “It’s great to have found a local supplier that gives the big boys a real run for their money ...”

“Serving the scientific community for over 10 years”

Local, UK & European Same Day Courier UK Overnight Packets, Parcels and Freight International Express Packets and Parcels, Logistics and Freight Packaging Exhibitions Pick & Pack Imports Consultation Hazardous, Medical & Dry Ice Shipments

JAG EXPRESS LTD 36 Clifton Road Cambridge CB1 7ED Tel: 01223 242250 Fax: 01223 242260 Email: ops@jagexpress.co.uk www.jagexpress.co.uk

About One Nucleus One Nucleus is an international membership organisation for life science and healthcare companies.

We are based in Cambridge and London, the heart of Europe’s largest life science and healthcare cluster.

Vision

London and Cambridge

For One Nucleus and our members to be the top European life science and healthcare network.

One Nucleus was formed in April 2010 by the merger of two regional life science networks – Cambridge-based ERBI and the London Biotechnology Network (LBN). Together we form a commercial, clinical and academic powerhouse. London and Cambridge are home to at least 60% of the UK’s life science industry base, four of the UK’s five Academic Health Science Centres and three of the world’s top six universities. The merger of ERBI and LBN recognises that the Cambridge-London network is an international life science “super cluster”.

Mission We will achieve this by maximising the global competitiveness of our members.

Organisation History Established in 1997, and formerly known as ERBI, One Nucleus is a notfor-profit, membership organisation located in Cambridge and London – the centre of Europe’s leading life science and healthcare cluster.

We have over 460 members including pharmaceutical, biotech, medical device and diagnostic companies and associated technical and commercial service providers.

One Nucleus’s mission is to maximise the global competitiveness of our members. For our science and technology-based members, that means being global leaders in the research, development and commercialisation of healthcare innovations that radically improve the quality of people’s lives around the world. For our business and professional services members, it means delivering exceptional services that significantly enhance the business performance of their clients.

The merger, driven by requests from ERBI and LBN members, resulted in a number of member benefits including: l A larger pool of companies to support business-to-business interaction l Membership of a cluster of international size, relevance and visibility l One membership providing discounted entry to events in London, Cambridge and further afield l Economies of scale supporting our Group Purchasing Scheme l An expanded training programme focused on the needs of our members

www.onenucleus.com

7

Welcome Welcome to the One Nucleus Company Directory for 2012. I am delighted that One Nucleus continues to be the largest life science and healthcare organisation in Europe, with over 460 members.

This Directory profiles all our members. Company details have been supplied to us by the companies featured. I hope these will help you to identify old friends and also new potential partners, customers and suppliers from the One Nucleus family.

We operate three levels of membership – Gold, Silver and Partner status (with Partners receiving all Gold member benefits). Please see inside for details of the benefits of membership if you haven’t yet joined us!

competitiveness, do contact me or a member of the One Nucleus team and we will be delighted to help. Do also check out our searchable online database of members on the home page of our website.

Times do not get any easier for the life science and healthcare sector or the wider global economy. I hope that One Nucleus support has been worthwhile for our members to date and we very much look forward to continuing to serve you and new members in 2012.

If you are interested in finding out more about us and how we can help you to maximise your growth and

www.onenucleus.com

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One Nucleus Services 1. Conferences and Networking Life Science Leadership Series (Cambridge) Responding to the changing needs of our members and the life science landscape. In 2011 One Nucleus announced the evolution of its traditional Cambridge BioPartnering Exchange to bring you the next generation in life science conferences.

The Cambridge Life Science Leadership Series delivers a cost-effective forum to showcase what is driving commercial deals, value creation, platform technologies and Government support in specific focused areas.

The inaugural events to date include Oncology; Healthcare Technologies; and CNS and Ageing.

For 2012 the themes will be: l

l

l

10

May 2012 - Infectious Diseases and Vaccines September 2012 - Healthcare Technologies January 2013 - Antibody Based Therapeutics

One Nucleus Directory 2012

Network Meetings (Cambridge) and BioWednesdays (London) Our Networking Meetings bring together our broad membership for networking and collaboration in an informal setting. Meetings are usually held in the afternoon or evening, starting with presentations on a relevant and current topic and ending with a networking session. Attendance ranges between 50 and 150 delegates.

Gold and Silver Members are entitled to free entry for up to three delegates.

Additional member delegates are charged at a discounted rate.

Bench-to-Boardroom (Cambridge) Bench-to-Boardroom was established in 2006 and is a 1 day event which includes a major exhibition, leading industry speakers, workshops and large scale Technology Showcases.

The event will provide communication, education and networking opportunities for scientists engaged in drug discovery whether in academia or the life science industry.

The event typically attracts over 500 visitors where delegates attend to meet suppliers with the best technology as well as to network with one another.

Our exhibition covers a wide range of suppliers to the industry, from equipment suppliers to providers of technical and commercial services, providing visitors with a key opportunity to source new suppliers and learn from the experts supporting the industry.

Keynote presentations from thought leaders will stimulate ideas and discussion.

There are a total of 8 workshops - each accommodating up to 20 delegates. The workshops cover technological, technical and commercial issues, with the aim of educating and informing. The plan is that as a result of attending, delegates will have increased their knowledge of how to do business faster and more economically, whilst retaining quality at all times.

Genesis Conference (London) Genesis has been running as London’s international life science networking conference since 2000. It is a showcase for UK and international life science, aiming to assist emerging life science companies in meeting investors and technology partners.

It also provides a stimulating forum for debate, led by a selection of high level keynote speakers and thematic experts in parallel session. The 1-2-1 partnering introduced in 2010 was expanded for 2011 with the inclusion of the UKTI International Zone where 1000 ‘speed’ meetings took place.

The first class exhibition features more than 60 UK and international exhibitors and with over 600 delegates these together make Genesis an international business hub for the life science sector.

2. Purchasing Scheme The One Nucleus Purchasing Scheme was set up to deliver low cost purchasing based on the combined spend of our members. The scheme saves One Nucleus members £3 million per annum. By joining together in the scheme, small businesses enjoy the same purchasing influence as larger companies and we are able to negotiate excellent prices and substantial savings in a number of product areas, including lab consumables, stationery and courier services.

It is the largest and longest running scheme of its kind run by a membership organisation for the sector in the UK. In addition to the Support Supply Agreements (SSAs) that are available to all One Nucleus members, Gold Members also have exclusive access to our Preferred Supply Agreements (PSAs) – tendered agreements with various suppliers.

3. Training Programme One Nucleus recognises that a company’s employees are its most valuable asset. Many rapidly growing companies overlook the need for ongoing training of their staff. One Nucleus has developed a portfolio of training courses designed to help life science and healthcare companies build an experienced and cohesive workforce. Employees should be able to contribute far beyond their technical capacity to enhance company growth and success as well as developing their personal skills.

We have developed a range of tailored training courses based on the needs of our member companies. We are constantly developing courses on new subjects as our members’ needs change. With this in mind, we are now pleased to have extended our training reach in the UK and now offer our training courses in London and Manchester, as well as Cambridge.

Courses are available to members and Non-Members. Non-Members pay a commercial list price rate, while Silver Members receive a discount from the list price and Gold Members receive increased discounts off the list price plus priority booking.

4. Special Interest Groups (SIGs) We run a range of Special Interest Group (SIG) meetings for our Gold members. Our SIGs include Human Resources, Operations which incorporate Facilities, Security & Business Risk and Health & Safety, Purchasing and Alliance and Project

Management. The aim of these meetings is to provide a platform for people doing similar jobs in different companies to get together informally and discuss the issues that affect their working lives. Meetings are typically held three or four times a year, starting with a presentation on a topic nominated by the SIG, followed by discussion and lunch. * One Nucleus reserves the right to exclude individual Gold Members from individual SIGs where we consider there to be a conflict of interest.

5. International Activities As an international membership organisation with global reach, we are delighted that 2011 saw a significant number of companies from outside the UK join the One Nucleus family.

Our international activities focus to a large extent on developing relations and tangible outcomes for our members with the US and wider Europe. That said, a wide range of our events are specific to other markets and in 2011 these included Canada and Australia to name but two.

In the US, we have formal relations with four of the top life science and healthcare membership organisations who support our members in accessing their networks and markets. In Europe, One Nucleus is the legal entity for the Council of European Bio Regions (CEBR) and we are a strategic partner in the large scale ABC Europe project – which supports SME’s across Europe.

Our suppliers are selected based on their ability to offer: l

l l l

l l

Substantial discounts (up to 50% off catalogue prices) No minimum order requirements No delivery or handling charges Guide payment terms of 30 days with the option of monthly consolidated invoicing Delivery next day if in stock Volume rebates for companies exceeding annual turnover targets

Savings vary from company to company, but on average our members save over 35% on their annual spend.

www.onenucleus.com

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Feeling the burn? Then take 3 easy steps

Search

Compare

Save

Did you know that a simple online purchasing solution can save your company thousands in cash? Answer these 5 quick questions to find out how you can reduce your burn rate.

Do you place orders with suppliers by: a) Phone/fax b) Different supplier websites c) An integrated, one-stop online solution Are you achieving the best prices possible on all your purchases: a) Not really sure b) Some of the time c) Always How is approval for purchases controlled in your organisation: a) Requestor gets tracked down when invoice arrives (most of the time) b) Budget holder signs off orders when she’s around c) Via fully automated online approval workflows

How do you ensure you’re getting the best price on purchases: a) The supplier sales rep assures me that I am b) I understand the market and know what the best deals are c) We use a dynamic online price comparison tool How do you know your order will reach you on time: a) Tell the lab manager it’s urgent b) The supplier’s usually pretty good so it should arrive on time c) I have full visibility of order status via my online purchasing system

Mostly a’s and b’s: seems like you could be burning more cash than you need to – contact us today to get on track to spend management success.

Mostly c’s: well done – along with thousands of Science Warehouse users you’re saving time and money and effectively controlling spend.

For over 10 years Science Warehouse has delivered online purchasing solutions and helped leading life sciences organisations save millions. Our partnership with One Nucleus offers members a dedicated procurement solution that saves time and cash and puts purchasing power in your hands.

Take the first simple step to savings success – contact Greg Staryk-Mills on 0333 600 6300 or greg.staryk-mills@sci-ware.com

www.sci-ware.com

We offer three levels of membership – Gold, Silver and Partner status. Partners enjoy all Gold member benefits and Silver Members receive basic entry-level benefits. Gold Members enjoy an enhanced range of exclusive services and benefits.

The following ‘benefits table’ compares the services available to Silver Members and Gold Members.

Member Benefits & Prices BENEFIT

NON-MEMBER

SILVER MEMBER

GOLD MEMBER

Profile in One Nucleus website member directory

8

4

4

Post news on the One Nucleus website

8

4

4

Post events on the One Nucleus website

8

4

4

Post jobs on the One Nucleus website

8

4

4

Network Meetings (Cambridge) £150 + VAT per

per delegate

3 free delegates £40 + VAT additional

3 free delegates £40 + VAT additional

BioWednesdays (London) £150 + VAT per

per delegate

3 free delegates £40 + VAT additional

3 free delegates £40 + VAT additional

Life Science Leadership Series

£420 + VAT

£295 + VAT

£175 + VAT

Genesis Conference

£325 + VAT

£26­0 + VAT

£195 + VAT

Exhibition Free Full Event Pass £75 + VAT

Exhibition Free Full Event Pass £50 + VAT

Free

Bench-to-Boardroom Networking Exhibition

One Nucleus Training List price 20%

discount

40% discount

Discounts under Support Supply Agreements (SSAs)

8

4

4

Discounts under Preferred Supply Agreements

8

8

4

Participation in Special Interest Groups

8

8

4

COMPANY SIZE

SILVER MEMBER

GOLD MEMBER

Individual/Sole Trader

£155 + VAT

N/A

Start-up, first year only, <10 employees

£225 + VAT

£935 + VAT

Small, <20 employees

£320 + VAT

£1,445 + VAT

Medium, 21-50 employees

£415 + VAT

£2,445 + VAT

Large, 51-150 employees

£520 + VAT

£3,645 + VAT

Extra large, >150 employees

£625 + VAT

£5,200 + VAT

Partner Programme (bespoke)

For more information please contact Tony at tony@onenucleus.com

All prices current up until March 2012

www.onenucleus.com

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To Sponsor One Nucleus “We at One Nucleus appreciate the need to ensure that sponsorship delivers value for money to each individual sponsor. Moreover we want to work with sponsors who can add real value to our core activities.”

- Harriet Fear CEO

In addition to membership, you can become involved with One Nucleus either as a Corporate Sponsor or by sponsoring one of our events.

One Nucleus has a successful track record in providing a platform for people from all walks of the life science and healthcare community to meet and interact. We achieve this through hosting a wide range of events in Cambridge and London, exhibiting at national and international events, hosting delegations from overseas, publishing newsletters and maintaining a content-rich website.

Our mailing list currently includes over 8,000 people working in the global life science and healthcare sector.

One Nucleus sponsorship will enable you to: 1. Raise your company profile in one

of the top cluster communities in

the world 2. Align your organisation with the

leading life science and healthcare

network in Europe 3.

Promote your company via One Nucleus not just to the Cambridge and London community, but to the global industry

4. Corporate Sponsorship attracts all

Gold member benefits 5.

plus one complimentary ticket to each of the One Nucleus Leadership Series conferences, Genesis and Bench-to-Boardroom.

If you would like to support One Nucleus as a Corporate Sponsor please contact harriet@onenucleus.com

CORPORATE SPONSORSHIP BENEFITS INCLUDE:

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One Nucleus Correspondence

Your company name on One Nucleus digital letterhead

Website

Your logo featured on all pages of the One Nucleus website

Your company name listed on the corporate sponsors’ page of the One Nucleus website

Your company profile and contact details on the corporate sponsors’ page of the One Nucleus website with a hyperlink to your website

One Nucleus Promotional Materials

Your logo on One Nucleus’s standard PowerPoint Presentation

Your logo on relevant promotional flyers

One Nucleus logo on your communications as appropriate

First refusal on further sponsorship opportunities e.g. Network Meetings and BioWednesdays

Newsletter

Your name on the One Nucleus’s pdf newsletters

Events and Conferences

Distribution of your literature by One Nucleus at the national and international events where One Nucleus is exhibiting e.g. MOU partner events.

One Nucleus Directory 2012

Current Corporate Sponsors

CORPORATE PATRON

www.onenucleus.com

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The One Nucleus Partner Programme offers a fully integrated value proposition to organisations seeking to play an influential and visible role in the development of the One Nucleus life science community.

Partner Programme The Partner Engagement Plan is developed on a bespoke basis, ensuring a good strategic fit with the partner’s own goals for the year ahead. Engagement may include benefits from the menu below, although this new approach to engaging key stakeholders is designed to be flexible. Alternative benefits may be agreed on a case-by-case basis such as bespoke seminars, profiling or support at overseas events.

Benefits l Complimentary Gold membership (value depending on size of the organisation) l Annual 1-2-1 meeting with the Chair and CEO of One Nucleus to discuss issues facing the life science community and possible One Nucleus interventions l Priority invitation to any ‘VIP – only’ events delivered by One Nucleus l Opportunity to join the Advisory Board for the one or more of our five flagship events: Bench-to-Boardroom, Genesis and the Life Science Leadership Series l Opportunity to speak at and/or moderate a panel debate at a One Nucleus event (based on relevance and experience) l Participation in the One Nucleus Special Interest Groups l Contribution of thought leadership articles to appropriate One Nucleus publications l Recognition by means of logo and hyperlink on the One Nucleus web site l Logo displayed at all One Nucleus events both in the UK and overseas l Opportunity to place one complimentary banner ad in an edition of the One Nucleus eNews l One complimentary delegate pass to each of the Life Science Leadership Series l A complimentary exhibition stand and delegate passes to each of the Bench-to-Boardroom and Genesis conferences

For more information about the Partner Programme (and costs) please contact Tony Jones: tony@onenucleus.com

www.onenucleus.com

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Life Science Leadership Series Responding to the changing needs of our members and the life science landscape, One Nucleus brings you the next generation in life science conferences.

Are you in focus? l Focus by therapy or health technology area mapping onto the way commercial deals are sought and evaluated l Focus brings seniority of delegate l Focus brings high quality key opinion leader debate l Focus your profile in the minds of others key to your next deal

Do you have an investment sat nav? l Assembling deal flow leaders from the Bio-Pharma, healthcare and investment community l Successful investment relies upon understanding the future clinical, regulatory and business needs l Debate will identify the future opportunities for entrepreneurs, investors and technology development organisations

The Cambridge Life Science Leadership Series delivers a cost-effective forum to showcase what is driving commercial deals, value creation, platform technologies and Government support in your area of interest. Do note the dates in your diary!

17 May 2012 - Infectious Diseases and Vaccines 26 September 2012 - Healthcare Technologies 23 January 2013 - Antibody Based Therapeutics Conference Agenda Framework:

Partnering, & Publication & Profile

l Plenary session of KOLs

l Online 1-2-1 business forum

l Successful deal case studies

l Presentation opportunities

l Emerging company showcase

l Limited exhibition and sponsorship opportunities

l Platform technology exemplars

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One Nucleus Directory 2012

l Legacy report to showcase relevant members

PROVIDING THE VERY BEST ENVIRONMENT AND FACILITIES FOR BIOTECH AND R&D COMPANIES LOOKING FOR A PLACE TO CALL HOME Developed with vision and executed with precision, at the Park youâ&#x20AC;&#x2122;ll enjoy unique and idyllic surroundings coupled with modern facilities and state-of-the-art accommodation.

This includes access to the conference facilities, restaurant, gym and 7 hole par 3 golf course.

The 250 acre low density scheme provides high quality accommodation in an attractive environment for science and technology based companies of all sizes.

Further phases of construction will extend the development to approximately 600,000 sq ft. which includes 1,515-28,000 sq ft laboratory suites at the new Science Village building available from May 2012.

The Park fosters a supportive and nurturing environment creating the ideal atmosphere to fuel discovery and innovation. Arrange a visit to see for yourself why top companies choose Chesterford Research Park.

BE INSPIRED

Savills Cambridge

savills.co.uk

01223 347 000

CHESTERFORDRESEARCHPARK.COM

Genesis The evolution of Genesis and the One Nucleus Life Science Leadership Series will take a further step in 2012/13 The Life Science Leadership Series will continue to build on the oncology, healthcare technologies and CNS and Ageing themes already launched by adding Infectious Diseases and Vaccines (May 2012), Healthcare Technologies (September 2012) and Antibody Based Therapeutics (January 2013). Each theme will continue to hold dedicated follow-on seminars throughout the year.

Our annual Genesis Conference will remain an intensive one-day event with a strong conference programme, exhibition, 1-2-1 partnering, networking and innovation awards. Genesis 2012 will bring together the participants from some of the leadership themes above, as we see some of the topics form the basis of the Genesis programme parallel sessions. The benefits of leveraging across our activities for participants are: l Providing a showcase forum for the debates within those themes to be aired l Strengthening the programme advisory board for Genesis with each leadership theme having a dedicated expert panel l Facilitating cross-themed interactions to stimulate innovation, collaboration and deal flow l Even further enhancing the quality of Genesis in terms of programme content and delegate mix, meaning the best possible business development forum for exhibitors, sponsors and delegates alike.

Oncology

CNS and Ageing

Jonathan Kearsey, Leads to Development

Mark Treherne, Senexis

Hazel Jones, MedImmune

Alan Palmer, MS Therapeutics

Simon Kerry, Karus Therapeutics Keith Blundy, Cancer Research Technology

Philip Oliver, Eli Lilly Mo Alavijeh, Pharmidex Michael Oâ&#x20AC;&#x2122;Neill, EOLAS

Rob Pinnock, MSD

Healthcare Technologies

To be announced

Kieran Murphy, GE Healthcare

Infectious Diseases and Vaccines

William Sprigings, BioPark

Therapeutic Antibodies

Stuart Hendry, Sphere Medical

Botanicals & Natural Products

Paul Whyte, Future Injection Technologies

Metabolic & Cardiovascular Disorders

Berwyn Clarke, Lab21

www.onenucleus.com

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Bench-to-Boardroom Bench-to-Boardroom 2012 is proudly sponsored by: Gold: Fisher Scientific and World Courier Bronze: Society of Biology Bench-to-Boardroom was established in 2006. It is a 1 day event which includes a major exhibition, leading industry speakers, workshops and large scale Technology Showcases. The event will provide communication, education and networking opportunities for scientists engaged in drug discovery whether in academia or the life science industry.

The event typically attracts over 500 visitors where delegates attend to meet suppliers with the best technology as well as to network with one another.

Delegates have the opportunity to submit a Scientific Poster to feature in the Poster Display, for Full Event Pass delegates and Academics this is complimentary.

Our exhibition covers a wide range of suppliers to the industry, from equipment suppliers to providers of technical and commercial services, providing visitors with a key opportunity to source new suppliers and learn from the experts supporting the industry.

Highlights of Bench-to-Boardroom 2012 are: l Opening Plenary Address by Sir Christopher Evans, serial entrepreneur and investor. l

A total of 8 workshops - each accommodating up to 20 delegates. The workshops will cover technological, technical and commercial issues, with the aim of educating and informing. The plan is that as a result of attending, delegates will have increased their knowledge of how to do business faster and more economically, whilst retaining quality at all times.

Workshops will be hosted by: HealthTech & Medicines KTN, Quotient Bioresearch Ltd, PHG Foundation, Global Regulatory Services, ideaSpace, Cyprotex, Fisher, and Deloitte.

l Three major 1 hour Technology Showcases giving companies the opportunity to demonstrate their latest technologies l An explosive show from Dr Hal. At 2011’s event he brought demonstrations such as the Exploding Ostrich Egg, Manufacturing Liquid Oxygen, Chemiluminescience, YBCO Levitation and the world’s biggest N2O/CS2 Barking Dogs.

Who should attend?

Research and operational staff working within life science, healthcare and technology companies.

Bench-to-Boardroom offers: l l l l l

22

60 exhibits from top industry specialists 2 Keynote Speakers 8 x 45 minute Workshops 3 x 1 hour Technology Showcases Opportunity for all delegates to take part in a Poster Display to showcase research and scientific excellence

One Nucleus Directory 2012

Dates for your Diary In 2012 we run an event in Cambridge and London every month:

FEB

22

Network Meeting Cambridge

MAR

Bench-to-Boardroom Newmarket

06

MAR

14

MAR

23

APR

Oncology Networking Seminar, in collaboration with Life Sciences Queensland Australia House Network Meeting Cambridge Partnering with Neusentis, an Entrepreneurial Pfizer Research Unit at the Forefront of the New Pharma R&D Model

18

Network Meeting Cambridge

MAY

BioWednesday London Hosted by Carpmaels & Ransford, Topic: Making your IP Investable

02 MAY

17 MAY

22 JUN

06

Life Science Leadership Series - Infectious Diseases and Vaccines Clare College, Cambridge CNS & Ageing Networking Semiar - Hosted by Eversheds BioWednesday London - Hosted by London BioScience Innovation Centre

JUN

Network Meeting Social BBQ Cambridge - Hosted by The Doubletree by Hilton

JUL

BioWednesday London - Hosted by Queen Mary Bioenterprises

27 04 JUL

18

Network Meeting Cambridge

SEP

BioWednesday London Hosted by Bristows

SEP

Life Science Leadership Series - Healthcare Technologies - Clare College Cambridge

03

OCT

BioWednesday London Hosted by CMS Cameron McKenna

17

OCT

Network Meeting Cambridge

07

NOV

BioWednesday London Hosted by Charles Russell

21

NOV

Network Meeting Cambridge

13

DEC

Genesis London

DEC

Network Meeting Cambridge

05 26

19

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RSA is a global leader in Executive Search, Interim Management and Talent Management to the Life Sciences industry with offices in China, Germany, Singapore, Switzerland, UK, USA and Partners in emerging markets.

RSA consultants talk to hundreds of industry leaders every day. Our network reaches every corner of the worldwide pharmaceutical, biotechnology and allied industries.

Established for 30 years, our unique blend of knowledge, teamwork and integrity has made us one of the world’s largest specialist recruiters - but we’ve never lost sight of the values we started with: respect, integrity, quality and professionalism.

EXECUTIVE SEARCH Top people are sought-after people. Finding them is easy, recruiting them is a skill in itself.

We use our experience to create the right approach for each key appointment, deploying our network and industry knowledge to achieve exceptional success rates.

INTERIM MANAGEMENT For the last 10 years, RSA has been the leader in Life Sciences Interim Management. RSA helps you engage the most talented people exactly when you need them. But we know you don’t always need them forever.

As the leading provider of interim managers to the life sciences industries, we have a network of offices ready to source and place the right people, at the right time, anywhere in the world.

RSA is the only life sciences company to achieve the strict membership criteria of the Interim Management Association (IMA).

RSA ESCALATOR MANAGEMENT© Having the right executives in place at the right time is a key element in growing a business.

Gaps in expertise can develop throughout the life of a company, but especially when it’s evolving. Key staff can find themselves under-used or overburdened, leaving companies unable to access the skills they need when they need them the most.

With Escalator Management© from RSA even early stage new companies can secure top talent as and when they need it. Small companies can punch above their weight when accessing business and technical expertise and large companies can reap the benefits of a flexible hiring pattern.

High quality managers are phased in as and when you need them, building your capability profile rapidly and efficiently, and changing it just as fast. Costs are predictable and transparent.

TALENT LIFECYCLE SERVICES At RSA we’re not just interested in the talent you need but the talent you already have. Understanding it, developing it, and adding to it for the future.

Our Talent Lifecycle Services© experts will work with you to maximise the value and contribution that people make to your business in the mid-to-long term. We’ll help you understand the competencies and qualities that match your 24

One Nucleus Directory 2011

strategy, and to predict which individuals will bring you real value in the future. We do this through assessment, development, coaching and engagement, all driven by the goals and values of your organisation.

By mapping the skills you have against the skills and talents you’ll need, we can help you create the optimum conditions for future success. Using our understanding of your business culture, along with appropriate tools and applied experience, we can help you define robust processes for assessment and selection.

Most companies plan for growth and profit. Few companies make detailed plans for talent development.

Be one of the few.

NON EXECUTIVE DIRECTORS Independent, experienced and authoritative. The qualities you look for in a non-executive director aren’t always easy to find in one person.

RSA’s register of non-executive directors facilitates networking, encourages dialogue about the non-exec role, and of course, helps match qualified individuals with key life sciences board vacancies in the public and private sectors.

Non-executive directors must work hard to maintain their independence and successfully oversee corporate governance. Their roles have never been more critical, or more complicated. Working at the top levels of our clients’ businesses and dealing with senior leaders in the industry, RSA is uniquely well placed to find individuals of the right calibre.

SO WHAT DO I DO NEXT? Wherever you are and whatever the time, we’re ready to get to work.

Call or email us now and speak to Kay Wardle: +44 (0)1707 259333 or kay.wardle@theRSAgroup.com

Purchasing Scheme The One Nucleus Purchasing Scheme has been running for over 12 years with an annual turnover exceeding ÂŁ7 million, with more than 80 Gold Members and is the longest running purchasing consortium of its kind in the UK. The Purchasing Scheme is also available to Bionow Premium members and SEHTA Premium plus members.

The Purchasing Scheme is directed by an Operations Steering Group comprising Gold member companies and delivers substantial cost savings to Gold Members with the vast majority of member companies saving more than their annual subscription to One Nucleus.

One Nucleus currently has 8 Preferred Supplier Agreements (PSAs) in place who undergo a rigorous tender process and are selected, not by One Nucleus but by the Steering Group and are only available to Gold Members.

They are: l

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Fisher Scientific - Providing laboratory consumables, laboratory chemicals and low value apparatus Sigma-Aldrich - Providing molecular biology, cell biology and cell culture products STARLAB - Providing pipette maintenance and calibration services Air Liquide - Providing laboratory gases and dry ice GE Healthcare - Providing servicing and maintenance of laboratory equipment Harts Office Supplies - Providing stationery, office goods, IT consumables and office furniture Deliver Plus - Providing courier services including dangerous goods and items on dry-ice BOC â&#x20AC;&#x201C; Providing Liquid Nitrogen Services.

Benefits of PSAs: l l l l

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No minimum order requirements No delivery or handling charges 30 day payment terms Option for monthly consolidated invoicing Internet ordering with additional discounts

One Nucleus can perform a cost-benefit analysis for Silver Members thinking of upgrading to Gold membership (and therefore access to PSAs) or companies wanting to become Gold Members.

Please contact Richard Dickinson 01223 896453 or richard@onenucleus.com.

One Nucleus also offers Support Supply Agreements (SSAs) which are available to ALL members. If sufficient interest is generated by an SSA, then the contract will be considered for upgrading to PSA status (following the tender process).

We currently have over 30 SSAs and the list continues to grow.

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26

COMPANY

SSA

CONTACT

EMAIL

PHONE

001 Ltd

Business Gas and Electricity cost reductions

Amanda Knaggs

Amanda.knaggs@001ltd. co.uk

0845 3892001

Amphora Research Systems

Electronic Laboratory Note Books

Rob Swan

robs@amphora-research.com

0845 2300160

AmeyCespa (Donarbon Ltd)

Waste Management Services

Andrew Goode

andrew@donarbon.co.m

01223 861010

ARCO Ltd

Safety and Maintenance Supplies

Matt Steed

matt.steed@karco.co.uk

07889 828 818

Bioline Reagent Ltd

Specialised Bio-Research ReagentsÂ

Josh Wright

jwright@bioline.com

07952 552181

Biopharma Technology Ltd

Freeze Drying Services and Training

Karen Carty

kcarty@biopharma.co.uk

01962 841092Â

Cambridge Research Biochemicals

Custom-made Peptides and Antibodies

Iain Hay

Iain.hay@crbdiscovery.com

01642 567180

Charles Kendall BioLogistics

Exhibition Services

Mike Barrett

mbarrett@charleskendall.com

02089 732430

Core Cambridge

Employee Health Management

Dan Coley

dan@core-cambridge.com

01223 429 998

DoubleTree by Hilton Cambridge

Hotel & Conference Accommodation

Gayle Martin

gayle.martin@hilton.com

01223 259 988

Eurogentec

PCR Services

Susanna Lovell

s.lovell@eurogentec.com

07920 060086

File and Data

File and Data Storage Services

Helen Stanton

Helen.stanton@officeteam. co.uk

01684 293393

Fire Safety Services

Fire Safety Services

Tony Pastore

tpastore@firesafetyservices. co.uk

07788 585 961

First Ascent

Leadership and Management Development Services

David Sales

david.sales@firstascentgroup. com

07802 467 148

First Sight Media

Multimedia Production Services & Web Communications

Mike Gilham

mikegilham@firstsightmedia. co.uk

0800 0728753

Flexible Lab Solutions

Automated Lab Equipment Rental Services

David Reed

david.reed@flexible-labsolutions.co.uk

01795 411540

FluidX

2D Bar-coded sample storage systems; Liquid Handling/Sealing Equipment & consumables

Emma Ryan

emma.ryan@fluidx.co.uk

07796 303277

Forecast Flow

Business Cashflow Forecasting

Lynn Munday

info@forecastflow.co.uk

0845 873 0540

Genesis Membership

Security Screening and Intelligence

John Clary

info@pa-ss.com

01954 261 392

Gram UK Ltd

Fridges and Freezers

Scott Gibson

scgi@gram-bioline.com

07771 563 829

Grundon Waste Management Ltd

Specialist waste removal

Andrew Stratton

clinical@grundon.com

01628 501 591

KISS Communications

Integrated Marketing Services

Simon Fryer

info@kisscom.co.uk

0208 123 4575

One Nucleus Directory 2012

COMPANY

SSA

CONTACT

EMAIL

PHONE

Labute Group Ltd

Printing Services

Dave Jones

sales@labute.co.uk

01223 420000

Leyton

R&D Tax Relief and Credits Services

Suzie Dennis

sdennis@leyton.com

02030 512183

Novus Environmental

Specialist Waste Removal

Power Solutions

Business Gas and Electricity Cost Reduction Services

Jeremy Taylor

jeremy@powersolutionsuk. com

01244 391500

Promega UK Ltd

Cell Based Assays for Drug Discovery

Matt Cook

matthew.cook@promega.com

07585 962903

Quality Care Cleaning Services

Commercial Cleaning Services

Paul Heales

Paul@qualitycarecleaning. co.uk

01223 833300

Remtec Selection Ltd

Medical Devices and Life Science Recruitment Services

Angelica Chhiba

Angelica.Chhiba@remtec. co.uk

01223 550876

RiverRhee Consulting

Team and Process Development and Training

Elisabeth Goodman

info@riverrhee.com

07876 130817

Schwartz MSL

PR and Communication Services

Richard Hayhurst

rhayhurst@schwartzcomm. com

02089 732430

Science Warehouse

Online purchasing

Jonathan Betts

jonathan.betts@sci-ware.com

01133 844 200

SRG

Recruitment

Richard Acton

richard.acton@srg.co.uk

07876 038813

S-Tech Insurance Services Ltd

Commercial Insurance

Dick Culpin

DickC@s-tech.co.uk

01223 445 439

S-Tech Insurance Services Ltd

Credit Insurance

Adrian Cooper

AdrianC@s-tech.co.uk

01223 445 428

S-Tech Insurance Services Ltd

Employee Benefits and Financial Services

Graham Sibley

GrahamS@s-tech.co.uk

01223 445 468

S-Tech Insurance Services Ltd

Personal Insurance

Nicola Chrebelska

NicolaC@S-Tech.co.uk

01223 445 447

The Digital Office

Photocopiers and Printers

Richard Kirby

richard.k@thedigitaloffice. co.uk

01462 810 071

The Shredding Alliance

Shredding and Recycling Services

Daniel Hawtin

daniel@theshreddingalliance. co.uk

08008 247799

Websters

Tax, Legal, Accountancy & Financial Planning Services

Cherryl Simpson

info@tax.uk.com

01223 507 080

WISER Recycling

WEEE Recycling

Paul Duggan

paul@wisergroup.co.uk

01480 464111

World Courier

BioPharm and Clinical Trial Logistics

Claire Brown

cbrown@worldcourier.co.uk Abradley@worlcourier.co.uk

07796 953673 07818 422978

0844 770 0012

Abigail Bradley

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KWS BioTest is an established contract research organisation that brings together internationally renowned scientific expertise in a commercially managed environment for the testing of prophylactic and therapeutic agents as treatments for human disease. We work closely with clients to understand the unique attributes of their products, to design appropriate research and development protocols and to develop a truly bespoke and individual programme. In doing so, we draw from our extensive expertise and range of technical skills, and are continually developing and validating new services to meet the demands of the modern pharmaceutical industry.

Human Disease Models Our unrivalled skill, knowledge and insight in human disease models is supported not only in the quality of the work delivered, but also the range of models offered.

This range is continually expanding as our scientists develop and validate more disease models for efficacy studies.

The disease range includes:

• Inflammation • Infection

To add value to any research programme additional capability is offered by KWS BioTest.

• • • • •

Vaccine development Immunogenicity and antigenicity testing Antibody production & screening Maximum Tolerated Dose (MTD) studies Pharmacokinetics

In Vitro

• Pain

KWS BioTest offers an outstanding range of analytical services which can be used in conjunction with in vivo studies, or in isolation in support of a client’s internal development. Expert advice is always available to support optimal assay design.

• In Vivo Support Services

The in vitro services range includes:

Research Consultancy

• Cell Biology

KWS BioTest benefits from a combination of unrivalled expertise and a thorough understanding of drug development.

These aspects make KWS BioTest a highly focused contract research laboratory with scientific integrity. KWS BioTest is, therefore, pleased to offer a research consultancy programme. This programme may be combined with experimental investigations or can be used purely at the advisory level.

• Autoimmunity • Allergy

• Immunoassays • Molecular Biology • Protein Biochemistry • Proteomics

Pathology Services KWS BioTest is a leading provider of specialist pathology services.

All of our histopathology is carried out by fully qualified histopathologists, and sections are prepared to a high standard by our externally accredited (NEQAS) laboratory.

The scope of consultancy can be tailored to meet your requirements and covers the following areas:

• Scientific expertise & justifications • Research programme & individual study design • Detailed interpretation & scientific review • Data analysis & statistical testing

A selection of the main histology services include: • Haematoxylin & eosin staining for general pathology • Specialist tissue stains for remodeling • Immunohistochemistry • Image analysis • Confocal microscopy

KWS BioTest Ltd Medical Sciences Building University Walk, Bristol, BS8 1TD

Email: info@kwsbiotest.co.uk

www.kwsbiotest.co.uk

Facilities Management Services Facilities management can be a real problem for small technology companies with exacting demands for laboratory, workshop and office space. Are you aware that One Nucleus provides a range of Facilities Management Services to help our member companies to expand or relocate?

We can provide project management for office and laboratory fit-outs (no job too small) and can help with laboratory service contracts, maintenance contracts, cleaning contracts, utility bills, insurance, purchasing and budgeting. As with all One Nucleus services, these are provided at discounted rates to members.

Our Facilities Management Services and Purchasing Scheme are managed

by Richard Dickinson, One Nucleus’s Director of Specialist Services, who has more than 10 years experience in laboratory and facilities management.

Before One Nucleus he worked for Cantab Pharmaceuticals and Astex Therapeutics, where he project managed the fit-out of a 45,000 sq ft building, plus another of 36,000 sq ft. In addition to procurement of lab and office equipment and furniture, he managed the move from one building to another over a weekend. Richard has extensive local contacts in the Cambridge area and is also NEBOSH certified in Health and Safety.

Richard can provide help by phone or email as well as providing full onsite consultancy. One Nucleus also provides

Health and Safety consultancy to members at a discounted rate. We provide support for health and safety policy development, training and audits.

Sara Cooper, Director of SJC Safety Training and Consulting and former Director of Health and Safety at the University of Cambridge, is One Nucleus’s principal health and safety consultant. She has worked on expert committees in the UK and for the EC, and for international clients setting up specialist facilities, including the design and operation of safety-critical laboratories.

During 18 years as a safety professional she has focused on safety auditing, management training and promoting safety at director level. She is a Fellow of IOSH, a Chartered Safety Practitioner, a Member of the Royal Society of Chemistry and a Member of ISTR. Please contact Richard on 01223 896453 or richard@onenucleus.com if you have any questions about One Nucleus’s Facilities Management or Health and Safety Services.

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Training Courses How it all began

One Nucleus is dedicated to providing bespoke training and support to the life science and healthcare sector, through a comprehensive portfolio of industry-specific training courses

In 2002 a group of biotech companies in Cambridge asked One Nucleus to develop training courses that addressed the needs of their employees in the drug discovery and development sector. After Interviewing around 70 companies to ascertain their training requirements, it was evident that new recruits to the industry wanted to gain a complete overview of the entire drug discovery and development process, from early stage research to the marketing of approved drugs. So we set out about developing our first course “Introduction to Drug Development”.

Since then we have significantly expanded our portfolio of courses for the life science and healthcare sector, working alongside our members to develop courses which address the current skills gaps within their organisations.

Each of our courses is designed by industry experts, and piloted to small classes, before being offered to all relevant companies. Feedback from the hundreds of delegates who have attended our courses has, without exception, been positive. Based on this success we are now delivering these bespoke courses to life science and healthcare companies and service providers throughout the UK and Europe.

One Nucleus recognises that a company’s employees are its most valuable asset. Many rapidly growing companies overlook the need for ongoing training of their staff. We have developed a tailored portfolio of training courses based on the needs of our member companies.

2012 Training Courses l 23 February Laboratory Health and Safety (Cambridge) l 24 February Laboratory Health and Safety (London) l 8 March Introduction to Drug Development: Scientific Professionals l 9 March Introduction to Drug Development: Non Scientific Professionals l 24 April Biological Safety: Management & Practice (2 days) l 14 May Introduction to Drug Development: Scientific Professionals l 15 May Introduction to Drug Development: Non Scientific Professionals l 18 May Commercial Awareness: from bench to balance sheet l 13 September Introduction to Drug Development: Scientific Professionals l 14 September Introduction to Drug Development: Non Scientific Professionals * Training course dates may be subject to change

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One Nucleus Directory 2012

Delegate Feedback: “The enthusiasm of the trainer for their subject made the whole day very digestible and easy to listen to” “As a non science professionsl it was very informatative and easy to undertans. This connected the dots for me” “Excellent day with plenty of relevant and interesting case studies”

Our current range of courses includes:

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Biological Safety: Management & Practice Commercial Awareness From Bench to Balance Sheet Cultural Awareness Workshops Directing Safely (IOSH Accredited) H&S for Committee Members and Representatives Introduction to Management Introduction to Drug Development Laboratory Health and Safety Mail Handling & Security in the Workplace Managing Safely (IOSH Accredited) Project Management Scientific Presentation Skills Small Molecule Drug Discovery - A Biological Perspective The Safe Use & Management of Laboratory Gases

Silver members receive a 20% discount on list prices and Gold members receive a 40% discount plus priority booking.

We are constantly developing courses on new subjects as our members’ needs change. With this in mind, we are now pleased to offer our training courses in London and Manchester, as well as Cambridge.

All courses can be delivered in-house, tailored and/or combined to create a bespoke training package which meets the exact needs of your organisation.

Please contact Philip on 01223 896457 or philip@onenucleus.com if you have any questions about One Nucleus Training courses.

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The highest quality service in custom-made peptides and antibodies Now celebrating over 30 years as the world’s second-oldest peptide manufacturer, Cambridge Research Biochemicals (CRB) combines a progressive scientific approach with a thorough commercial instinct.

Customers are at the heart of our business. Specialising in the chemical synthesis of peptides and polyclonal antibodies, we provide a highly focused, highly personal level of service. With long-standing relations with some of the world’s largest pharmaceutical companies, we provide individual, not off-the-shelf solutions.

Jointly owned by Emily Humphrys and Alison White – scientists with commercial backgrounds – our company is keen to build on its success and experience with new strategic partnerships. We look for small, specialist biochemical businesses and research institutes whose work complements ours and whom we can help grow and expand.

What we offer: Peptide synthesis

Fluorescent dyes

Tailored products and services

Antibody production

PNA synthesis

Partnering opportunities

Dye and Radio-labelling

Increased market exposure

High standards Outstanding customer service Operational excellence

CRB proudly sponsors: Cambridge Cell Biology Seminars

Cambridge Research Biochemicals

10 Belasis Court, Belasis Hall Technology Park, Billingham, Cleveland TS23 4AZ United Kingdom www.crbdiscovery.com T +44 (0)1642 567180 F +44 (0)1642 567181 E enquiries@crbdiscovery.com

Cambridge Institute of Medical Research PARTNER

Babraham BIOSCIENCE TECHNOLOGIES

Special Interest Groups Special interest groups are typically run four times a year and are a Gold member benefit.

HR - Any Gold member of One Nucleus who deals with personnel issues is welcome to attend meetings of the HR Special Interest Group, whether you’re an experienced HR professional, just learning the ropes or only get involved because there’s no-one else to do it!

The group meets regularly throughout the year for a series of informal and proactive workshops and seminars on HR topics directly relevant to the biomedical sector. The sessions are run by Eleanor Freeman, a partner at Cambridge Employment Law LLP. The events offer the opportunity to learn, network and share best practice in a ‘safe’ environment.

Eleanor also provides a monthly newsletter updating you on the changes to employment law you need to know and highlights issues relevant to the biomedical sector.

Cambridge Employment Law LLP is a specialist employment law practice, advising both employers and employees. Eleanor Freeman has

particular experience advising the biomedical sector. Find out more at: www.cambridgeemploymentlaw.com.

Operations which incorporates: Facilities - Relevant to people who are responsible for the day to day running of their company’s facilities.

Discussions focus on key areas of facilities management such as equipment management and bench marking the cost of running labs and offices.

managers who wished to meet with their industry peers, topics cover stress management, waste reduction, legislative updates and the overview of the challenges facing health and safety managers.

Purchasing - This SIG supports One Nucleus’s well-established Purchasing Scheme, where Gold Member companies gain significant discounts on items such as laboratory consumables and office supplies and services such as pipette maintenance.

Health & Safety - The aim is to provide a platform of communication for Health & Safety Managers.

Alliance and Project Management - This SIG is operated for people who have a role in running projects within companies, and/or across alliance partner companies. Our purpose is to provide support and networking opportunities - particularly to people who may not have not had a great deal of formal training or many years experience in cross-functional working and project management.

These meetings were developed at the request of health & safety

* One Nucleus reserves the right to exclude individual Members from individual SIGs where we consider there to be a conflict of interests.

Security and Business Risk - Brings together individuals responsible for both security and operational management. Recent talks have covered industrial espionage, security contractor management and managing risk in a laboratory setting.

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One Nucleus Directory 2012

European Activities One Nucleus’s mission is to maximise the global growth and competitiveness of our members. One of the key strands of our strategy is to internationalise our activities and encourage our members to take advantage of platforms and initiatives we work on in this regard. We recognise that for UK companies to be strong, they need to have access to and relations with other exceptional global companies. The sector is global and the success of it hangs on us working in partnership for mutual benefit.

With this in mind, One Nucleus plays an important role as partner in two ECfunded projects:

1. ABCEurope ABCEurope is an intercluster project coordinated by the Milan Innovhub (Milan Chamber of Commerce) and is funded by Europe Innova. It brings together 13 biotechnology clusters across Europe including One Nucleus as a leading partner.

The overall objective of the project is very tangible: raising the standard of services to SMEs and defragmenting the delivery of such services to SMEs across Europe.

Within the framework of this project, One Nucleus launched the following activities during 2011: l ABCEurope Bioentrepreneur boot camp It is within the framework of this project that One Nucleus organised, in partnership with ideaSpace Enterprise Accelerator, the inaugural ABCEurope Bioentrepreneur boot camp from 13-15 June 2011 in Cambridge.

This intensive 3 day course for life science start-ups was the first in a series of five events, with the subsequent four being held in a different European city each time. l ABCEurope BioTechnology Showcase A further ABCEurope activity is the organisation of a series of technology showcases to facilitate industry/ academia interaction and to promote European research in biotechnology at an international level.

The technology showcases allow researchers from academia and SMEs to present their innovative technologies to an industry audience. Our Genesis 2011 event saw an ABCEurope Technology Showcase on Infectious Diseases and Immunity embedded within it.

Two ABCEurope Technology Showcases will be held during 2012 in: -

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Malmo 27 March during Life Science Investment Day Scandinavia 2012 Liege 18-19 April during Biomedica 2012

l Other activities Other ABCEurope activities include the creation of a network of European NonExecutive Directors (NED’s) and virtual matchmaking events between SMEs from different European regions.

2. India The European Business and Technology Centre (EBTC) aims at further developing EU-India trade and business relations. The project is coordinated by Eurochambres, and includes One Nucleus and 15 other European partners.

The Centre’s activities are organised in four key sectors: Environment, Energy, Transport and Biotechnology.

The Milan Innovhub (Milan Chamber of Commerce) is coordinating the Biotechnology cluster which comprises One Nucleus and COPCA (Barcelona).

The aim of the project is to create a Centre which will become a point of reference for European companies wanting to enter the Indian market.

The Centre is planning to achieve this by acting as a multiplier and facilitator, increasing the understanding among EU SMEs and researchers about the opportunities offered by India; and provide an active link between policy makers and private bodies.

If you are interested in receiving more information about the above projects and activities please contact One Nucleus’s European Project Manager, Gigi Møller (01223 896458 or gigi@ onenucleus.com).

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Strategic Relations with Top Us Clusters One Nucleus members have expressed a desire for us to develop strategic partnerships with other leading clusters (specifically in the US) and to provide members with access to potential partners and investors from other global centres of excellence. With this in mind, we have signed four separate Memoranda of Understanding (MOU) with the top US clusters organisations: MassBIO, MassMEDIC, BIOCOM and BayBIO.

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One Nucleus Directory 2012

In October 2009 we signed our first Memorandum of Understanding (MOU) with MassBIO to encourage and promote cooperation and deal flow between members. The MOU confirmed a commitment to facilitate transatlantic investment and partnering by encouraging collaborations between each group’s member companies. One Nucleus and MassBIO now promote each other’s investment and partnering events, offering members reduced rates and speaking opportunities. Importantly and as a direct result of the formal relationships, One Nucleus members can also benefit from being offered a ‘soft landing’ by the US cluster organisation when members are looking to set up, do business or identify potential partners or investors on the East and West coast US. A second MOU was signed in December 2009 with the Massachusetts Medical Device Industry Council (MassMEDIC), to actively encourage cooperation and collaboration between UK and US companies in the medical device sector.

Subsequently, we signed a third MOU with Joe Panetta of BIOCOM (the cluster group in San Diego) at BIO 2010 and a fourth MOU was signed with Gail Maderis, President of BayBIO (the cluster group in San Francisco) at Genesis in December 2010.

We are delighted that these strong relationships have led to tangible outcomes for One Nucleus and US partner members so far. These include: l

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One Nucleus being asked to host the visit to the UK of the Governor of Massachusetts in March 2011 – to create a platform for him to deliver his keynote address on life sciences, which we were proud and delighted to arrange

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Continued strong and collaborative support between One Nucleus and the four MOU partners including on-going discussions about profiling of each others’ organisations and members in- market

Over ten One Nucleus members attending BayBIO’s annual conference in 2011 at significantly reduced rates. We negotiate specific packages of support for our members on an ongoing basis A visit to Cambridge and London by BiotechNation in January 2011 where many One Nucleus members had one to one interviews with Moira Gunn

We make it our business to understand yours Clear, straightforward advice for all your intellectual property issues

London : +44 (0) 20 7283 8989 Birmingham : +44 (0) 121 236 0484 Merseyside : +44 (0) 151 647 6746

email : cleardirection@forresters.co.uk website: www.forresters.co.uk

Experience

-

Action

-

Understanding

Futureproof technology is in our DNA Ploughshare is your gateway to unique biotechnology solutions from the globally renowned Defence Science and Technology Laboratory (Dstl).

Dstl’s long biotech sector heritage goes back over a century. Ploughshare’s unrivalled connections, experience and support enable you to deliver exceptional commercial results.

Biotech solutions: > Vaccine Development > Skin-care / Cosmetic

> Diagnostic Tools > Detection / Decontamination

Biotechnology that fits your needs

T: +44 (0) 1794 301602 E: info@ploughshareinnovations.com www.ploughshareinnovations.com/bio www.onenucleus.com

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Clinical Research

Data Management/Services

Medical Communications

Consultancy

SILK|EDC

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One Nucleus Directory 2012

One Nucleus Collaborations One of the clear messages I receive regularly from members is a plea to work collaboratively with other organisations and cut down the duplication of efforts in the UK. This feedback has helped us carve out our strategy and this, combined with a request from members to create connections with international organisations who can help our members grow, is at the heart of what we stand for.

A clear recognition of the above was the formal merger of ERBI and London Biotechnology Network in May 2010.

We also of course have our four Memoranda of Understanding in place – with BayBIO, MassBIO, MassMedic and BIOCOM in the USA. The spirit of partnership is very strong in the One Nucleus team and we continue to enhance our offer for members, with partnerships with other organisations. These include: l

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An exclusive deal with Worldwide Business Research (WBR) for their events A deal with Pharma Licensing Group (PLG) for mutual member benefit A fantastic insurance deal for early stage companies with S-Tech

We are also working closely with other membership organisations in the UK, including the BIA (the national trade association), Bionow (a membership organisation based in the North West),

SEHTA (the South East Healthcare Technologies Association) and Nexxus (Scotland). At the end of 2010 we signed an agreement with Bionow for their members to have access to our Group Purchasing Scheme and at the end of 2011 we agreed a similar arrangement with SEHTA for their members to have similar access– thus creating benefit for their members in terms of savings and importantly increasing the critical mass of companies using our scheme – which puts us in a very strong position when re-negotiating contracts with Preferred Suppliers.

We also have deals in place with other international organisations, for member benefit. These include reciprocal support from TVG Group (who run BioPartnering Europe and other major events around the world) and EBD Group (who run Bio Europe and BioPharm America, to name but two).

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Heptares Therapeutics is a drug discovery company focused on identifying novel drug candidates targeting high-value, validated G-protein-coupled receptors (GPCRs) in multiple disease areas.

We have created Kershaw Technology Services to support the development of medical devices. We have extensive experience in the following areas: l Development of carded and knitted fibrous products l Development of fibre spinning processes l Development of gel products l Application and processing of polysaccharides l Development, analysis and modelling of chemical processes l Project management of product development and launch processes l Physical and chemical characterisation of raw materials and products l Development of experimental laboratory scale processes and facilities l Development of pilot scale facilities for clinical trial manufacture l Development of manufacturing facilities l Manufacture of clinical materials l Product stability and shelf life evaluation of products l European medical device regulation

Contact Details Mob: 0776 3256 112 Email: enquiries@kershawtechnologyservices.co.uk Web: www.kershawtechnologyservices.co.uk

The Companyâ&#x20AC;&#x2122;s unique StaRâ&#x201E;˘ technology enables Heptares to engineer and purify stable GPCRs to which it can apply contemporary drug discovery approaches, such as crystallisation and structure-based design, biophysical analysis of ligand interactions and fragment screening.

This unique approach is expected to radically improve the chances of finding novel drug candidates (small molecules and biologicals) to previously intractable targets and will enable the development of safer and more selective therapeutic agents.

Based on this integrated drug discovery capability, Heptares aims to progress promising candidates internally and through strategic alliances.

For more information, please contact: Dr Barry Kenny Heptares Therapeutics Ltd BioParkBroadwater Road Welwyn Garden City Hertfordshire AL7 3AX, UK Tel: 01707 358627 Email: barry.kenny@heptares.com Web: www.heptares.com

ANABIOTEC nv

AnaBioTec is a cGMP compliant contract laboratory providing physical, chemical, biochemical and microbiological analytical services to the pharmaceutical and biopharmaceutical industries.

Established in 1998, AnaBioTec provides a high quality and responsive service to clients of all sizes across Europe and in the US from its premises in Ghent, Belgium.

Contract services include method development, method validation, stability studies and release testing for both early and later phases of development, and for both large and small molecules. The laboratories have been successfully inspected by the FDA and the European Authorities. AnaBioTec offers a skilled and committed team of analysts and scientists with a wide range of experience and knowledge. A dedicated Project Manager is assigned to your project throughout its duration, ensuring frequent feedback on project progress and a flexible and timely response.

Please visit our website at

www.anabiotec.com,

or contact:Daniel Jones, Business Development Manager.

+44 7715 352165; daniel.jones@anabiotec.com

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One Nucleus Directory 2012

Your proven drug development partner

Do you need commercial support during deals or fund-raising?

Each QSCL consultant has 20 years international experience.

We develop drugs from post-discovery through to clinical proof of concept and prepare expert reports for marketing applications.

Services include: ▲ Financial analysis, including decision tree modelling ▲Company, market and technology evaluations ▲ Development of business and marketing plans

Q Scientific Consulting Limited info@qscl.co.uk www.qscl.co.uk

Tel: +44 (0)1423 522406

Asset and Systems Support Management Business continuity planning Equipment and asset audits carried out Cost saving support models developed Whole life costs for capital assets identified Relocation planning and management • Put a business continuity plan in place to ensure your business can operate beyond unexpected disruption • Ensure you are fully in control of cost relating to your capital equipment. Have an asset audit carried out and all important associated information logged in to a management system • Review all your current support requirements for capital assets, and implement cost saving business focused support • Put processes in place to capture all whole life costs incurred from use of capital assets

Available for consulting, part-time / interim positions or project support Contact: Lindsey Foulkes BSc, PhD springfield.analysis@gmail.com Tel: 07733 364 268

place for success Newmarket, Mildenhall, Brandon, Red Lodge and surrounding villages offer some of the best countryside in the country, access to the finest academic and research facilities of Cambridge enhanced by University Campus Suffolk, competitive land and property prices and a strong transport network including the A11 from London to Norwich, the A14 from the East Midlands to east coast ports and access to international airports.

• If your occupying new facilities, or relocating have your occupation planned and managed by an experienced professional

Contact: John Moore Tel. 01763 24761 Mobile. 07714 950 186 Email. john@assetandsystems.co.uk

www.assetandsystems.co.uk

For further information on how to benefit from expansion within Forest Heath contact The Economic Development Team on +44 (0)1638 719471 or econdev@forest-heath.gov.uk who will be pleased to handle any land or property enquiries

www.onenucleus.com

43

Pharma & Medical Solutions RAUMEDIC AG,is a flexible company full of bright people and new ideas, operating from state of the art Class 7 clean room facilities near Nuremburg.

Current research and development includes novel medical grade material alternatives, micro extrusion, devices with electronics, as well as a number of exciting custom developments for the medical device and pharma industry.

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One Nucleus Directory 2012

RAUMEDIC have significant experience in delivering design, development and full contract manufacturing services including full high volume automation with robotic handling, for your medical or pharma device requirements. Our engineers will work with you to advise on materials, design and construction, automated manufacturing, packaging, sterilisation and validation protocols, as well as quality and regulatory support to enable you to CE mark your product.

Contact our UK team Paul Flavell (07785 714815) or Mark Laycock (07802 333916) for further information. info@raumedic.com www.raumedic.com Raumedic UK Hill Court Ross on Wye, UK HR9 5QN

Cool under pressure.

MNX specialises in the global shipment of time- and temperature-sensitive materials.

Every aspect of life sciences transportation is critical. Thatâ&#x20AC;&#x2122;s why MNX offers:

MNX No Limits Services:

Door-to-door pickup and delivery any time you need it

First Flight Out

Providers of validated packaging systems for all temperature ranges

Dedicated Hand Carry

Coolants and packaging available worldwide

Charter

Specialists in cold chain requirements

Expedited Ground

Clinical drug supply and transportation of biological specimens *OEJWJEVBM TIJQNFOU NPOJUPSJOH XJUI SFBM UJNF OPUJm DBUJPO Global regulatory and compliance guidance including the carriage of dangerous goods No Limits. No Compromises. No Worries.

For expert care of your clinical trials and research-related shipments, you can depend on MNX.

MNXâ&#x20AC;&#x2122;s worldwide network serves more than 190 countries.

0Gm DFT /PSUI "NFSJDB ] &VSPQF ] "TJB ] "VTUSBMBTJB ] "GSJDB

mnx.com | +44 (0) 20 8607 5530 sales.lhr@mnx.com

Bioincubator Blossoming at Babraham Acknowledged as one of the UK’s leading enterprise hubs, home to both world-class academic research and commercial biomedical companies, the Babraham Research Campus has established itself as a hub of bioscience innovation at the heart of the Cambridge cluster.

With world-class facilities and a vibrant research community, the Babraham Research Campus continues to expand.

Following the award of £44M to support bioscience innovation, as part of the capital/infrastructure investment for science announced by Government in the 2011 budget, developments have been moving at a pace on the campus.

The opening of Babraham’s fifth Bioincubator Building, Moneta, in April 2012 underscores Babraham’s continuing commitment to nurturing early-stage enterprises and supporting biomedical innovation in the region.

At the cornerstone of the campus is the internationally regarded Babraham Institute, which receives strategic funding from the Biotechnology and Biological Sciences Research Council (BBSRC) and underpins government’s national responsibilities for life sciences research and training. Research is focussed on generating new knowledge of the biological mechanisms underlying ageing, development and the maintenance of health. The Institute also aims to promote knowledge exchange and to facilitate partnerships to translate innovative science into viable ventures. Discoveries are commercialised through the Institute’s commercial arm - Babraham Bioscience Technologies (BBT) Ltd - an example being the creation of the spin-out company Crescendo Biologics.

Investing in Infrastructure for Bio-innovation BBT has successfully developed the campus infrastructure over the last 14 years; central to this are Babraham’s Bioincubator buildings, which offer serviced facilities, on attractive, flexible terms, to support new bioventures and catalyse the commercial exploitation of biomedical research.

Around 30 early-stage biomedical companies are based at Babraham, delivering new products and innovative solutions for the healthcare challenges of the 21st century. To date, 75 companies have passed through the Bioincubator and these companies have raised in total over £400M in equity finance.

The campus continues to expand despite the current economic climate. The first part of the development plan funded by the £44M investment has been the construction of Babraham’s fifth Bioincubator Building – Moneta. Offering 20,000 sq ft of laboratory and office accommodation in units of circa 600 sq ft, Moneta will complete the development of the south part of the Babraham Research Campus. The first tenants are expected to move into the premises early April 2012. On completion of Moneta, the Babraham Research Campus will provide a total of around 85,000 sq ft lab/office space.

In January 2012 outline planning permission was granted for further ‘follow-on’ R&D facilities, some of which will commence construction in April 2012. Derek Jones, BBT’s Chief Executive said, “The additional funding to the Babraham Research Campus is enabling us to build on our current strengths in research and innovation. We have been able to initiate further developments in infrastructure and facilities to support the life sciences industry in both the

region and the UK and look forward to welcoming more companies to our new facilities.”

The hub of activity continues to draw companies to the campus, most recently MISSION Therapeutics, a spinout company from Professor Steve Jackson’s Lab at the Gurdon Institute (University of Cambridge). Backed by £6M series A funding - led by Sofinnova and including Imperial Innovations, SR One and Roche Ventures as investors - the company will translate cutting edge cell biology research on DNA repair into drugs that will markedly improve the management of life-threatening diseases, particularly cancer.

Some of the most exciting biologics and antibody companies in Europe have recently established themselves at the Babraham Research Campus including: Kymab, a spin out from the Wellcome Trust Sanger Institute; Bicycle Therapeutics from the MRC-LMB; Recombinant Antibody Technology; and Crescendo Biologics, whose technology is derived from BBSRC-funded research.

“Much of the pioneering work on monoclonal antibodies was carried out at the Institute and in the Cambridge area, so it is particularly thrilling to see so much commercial expertise gravitating to Babraham.”

- Professor Michael Wakelam, Babraham Institute Director

BABRAHAM BIOSCIENCE TECHNOLOGIES LTD (BBT) n

Catalysing Academic-Commercial Collaboration Another clear draw of the campus is the opportunity for companies to interact and collaborate with Institute research groups, where BBSRC-funded research is directed towards understanding the basic bioscience underpinning lifelong health and ageing. Babraham research has given insight into conditions like hypertension, heart failure, autoimmunity, infertility, cancer and neurodegenerative diseases such as Alzheimer’s Disease and today has a strategic focus on ‘healthy ageing’, to understand the biological mechanisms underpinning the determinants and the maintenance of lifelong health.

The Institute is committed to knowledge exchange and facilitating academic-commercial links to drive innovation and wealth creation. The translation of the Institute’s pioneering research has resulted in several patent applications and commercialisation is achieved through licensing technologies, consultancies and creating spin-out companies. Several events are organised throughout the year to bring together institute scientists with companies on site, for example CEOs’ Breakfasts, the campus Knowledge Exchange Forum and social events. Over 80% of the companies on site work closely with the Institute, through collaborating with scientists or using Institute services and facilities.

Accelerating Innovation in the TDL Another unique offering at the Babraham campus is the Technology Development Laboratory (TDL), established

by BBT to provide access to resource, equipment and space so that early-stage concepts can be developed to commercially-viable opportunities. This provides the benefit of offering bespoke, state-of-the-art R&D services and scientific assistance across many fields including molecular biology, protein biochemistry, cell biology, immunology, medicinal and synthetic chemistry. A suite of equipment for biopharmaceutical development, supported by funding from the East of England Development Agency (EEDA), includes a medium-scale cell culture and fluorescence-based assay platform, together with state-of-the-art protein purification and analysis systems. EEDA funding also supported the purchase of a Biacore T200, which is available at a reduced day-rate to One Nucleus members.

The TDL is available to campus companies, Institute scientists and also external biomedical companies. For example, Cellexus Ltd, based at the Hinchingbrooke Business Park developing bioreactor systems, used the facility to run evaluation experiments for three weeks. Clive Mason, Technical Manager explained, “The access to short term rented lab space within the TDL at Babraham has been of real benefit to Cellexus Ltd. The speed with which the contract was set up, the flexible approach and the competitive pricing all made for a smooth process. Additionally the TDL staff was readily available for advice and access to the on-site stores facility was another key benefit. The flexible provision of such short-term space is not, to my knowledge, available elsewhere in the Cambridge area.”

Babraham has recently joined forces with The University of Cambridge’s ideaSpace to offer a more connected support mechanism for early-stage companies to help to accelerate enterprise. Ventures will have dual access to the ‘plug and play’ laboratory facilities in Babraham’s TDL and the coworking community at the ideaSpace in the Hauser Forum.

“Many companies don’t need full time access to lab facilities but want to access it on an ‘as needed’ basis.

The superb facilities at Babraham can help ideaSpace support a wider range of members from different sectors who require such specialist facilities.”

- Dr Belinda Clarke, Director of External Relations at ideaSpace.

Access to world-class scientific facilities Companies located in Babraham’s Bioincubator also have access to the Institute’s world-class scientific facilities.

Recent BBSRC investments include a £1.6M Next Generation Sequencing facility, a £1.5M Mass Spectrometry suite with special application for lipidomics’ analysis, £23M world-class rodent animal facilities, in addition to bioinformatics, FACS analysis, imaging, gene targeting and monoclonal antibody production.

Andrew Sandham, Chairman and CEO of Kymab said, “We evaluated many locations in the Cambridge area to found our business. We chose the Babraham Research Campus because of the high quality of research laboratories, its proximity to academic centres of excellence and its flexibility in providing the capacity and services we will need as we expand our R&D operations.”

Derek Jones, Chief Executive of BBT added, “The creation of a supportive, entrepreneurial environment promoting bioscience innovation is one of our key objectives as we continue to develop the Babraham Research Campus. I am delighted at the progress we have made and the opportunity that our new buildings present, supporting bioscience innovation and wealth creation for the UK.” Babraham Bioscience Technologies is currently open to enquiries from potential tenants; For further information about the facilities within Moneta, please contact Nicola Kinsey, 01223 496334.

“Babraham was chosen as the site for our laboratory because of the impressive facilities available there, the great location and the track record of support for small companies shown by BBT.” - Dr John Tite, CEO of Bicycle Therapeutics

dis.tinc.tive [di-stingk-tiv] - adjective 1. serving to distinguish; characteristic; distinguishing: the distinctive stripes of the zebra.

2. having a special quality, style, attractiveness, etc.; notable.

- distinctively a. distinctiveness n.

7th Floor | Aidan House | Sunderland Road | Gateshead | NE8 3HU T: 0845 884 2385 | E: enquiries@distinctivegroup.co.uk

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One Nucleus Directory 2012

Cambridge Science Park For over 40 years Cambridge Science Park has been attracting some of the world’s greatest and most innovative research and development (R&D) companies. Today, the Park is home to over 90 companies ranging from small start-ups to large multinationals, with over 600,000 sq ft occupied by bio/ medical companies, and the number continues to grow.

In 2011, the Park announced the arrival of two exciting new biotech companies: Discuva and Endomagnetics. Discuva is a UK company which exploits its unique technology platform to revolutionise the treatment of disease caused by bacterial infection, and provide a pipeline of next-generation targeted antibiotics to meet the current, critical, unmet need in the clinic. Endomagnetics addresses cancer staging and healthcare challenges through the application of advanced magnetic sensing technology and nanotechnology.

Cambridge Science Park strives to provide a setting in which companies can grow and flourish. Experience of the R&D sector has shown that the fast pace of development means companies need flexible leasing options which allow them to develop and respond to changing market conditions, and has highlighted the widely varying needs in premises infrastructure and design. The Park is able to offer that flexibility of approach and attention to detail to every company at the Park. The vast expansion of Dr. Reddy’s and Domainex during 2011 is testament to this. Dr. Reddy’s has more than quadrupled, while Domainex has more than doubled, the size of its facilities at the Park in the past 12 months.

From its earliest days, Cambridge Science Park has benefited from a park-like, low-density site, providing an inspirational setting for the companies that reside there. In addition, the Park provides a range of first-class facilities including stateof-the-art conference, restaurant and bar facilities, a health and fitness club, and children’s nursery.

For information about the availability of property at Cambridge Science Park, contact Michelle Cantwell at Bidwells on 01223 559565.

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51

Don’t let the financial climate restrict your research!

Because our main business is with industry, we are able to offer the very same quality products at attractive prices to researchers.

Delivery is FREE to UK research organisations.

Europa Bioproducts is a major European distributor of specialty biochemicals, immunologicals and reagents which are used by companies manufacturing clinical diagnostic kits and the R & D/HTS/Analytical and QA departments of biopharmaceutical companies. In the last 20 years we have shown consistent growth culminating with our best year in 2011. Our web site lists the minimum quantity for each product but we are able to offer substantial discounts for larger quantities, multiple orders or standing orders.

Our product areas are: n ProZyme’s tools for glycan preparation (GlykoPrep), profiling and

sequencing for Biopharmaceutical companies. n Krishgen’s Host cell protein assays for Biopharmaceutical companies. n Antibodies for research and for manufacturing ELISA reagents. n Fluorescently labelled proteins and antibodies for Flow cytometry,

Luminex, Multiplexing and FRET applications. n Europium Cryptate and custom labelling services for TR-FRET

applications. n Bovine serum albumins, animal sera and immunoglobulin’s for

manufacturing ELISA reagents. n Natural and recombinant proteins for manufacturing ELISA reagents. n Biochemical’s and enzyme substrates for Diagnostic reagent

manufacturers.

We are certified ISO9001:2008 and are a DEFRA audited facility for handling animal by product intermediates under regulation (EC) 1069/2009. If you are experiencing difficulties importing products derived from animals then please contact us. We may be able to import on your behalf.

We are very receptive to customer’s special requirements so please visit: http://europa-bioproducts.com for our complete product listing.

Or call us on Tel: +44 (0)1353 721118 ENGLISH AND GERMAN, MONDAY - FRIDAY 9AM - 5PM

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One Nucleus Directory 2012

Europa Bioproducts Ltd, 15-17 North Street, Wicken, Ely, Cambridgeshire CB7 5XW

Experienced supplier of ICT services to Biotech and Research companies, covering: • ICT Support Taking care of your everyday office support requirements • Hosting Covering email, servers, websites, offsite backup, disaster recovery, applications and phones • Connectivity Provider of quality internet services to business parks and multi-tenanted offices (including Granta Park and Babraham)

S-Tech Insurance Services Ltd 154-156 Victoria Road Cambridge CB4 3DZ Members free-phone enquiry number 0800 8406540

Independent insurance, financial services & risk management group

Tel: 01223 324233 Fax: 01223 464150 Web: www.s-tech.co.uk Email: info@s-tech.co.uk

S-Tech Insurance Services Ltd We are pleased to provide a comprehensive insurance service for One Nucleus members and are delighted to be acknowledged as their preferred insurance supplier. Whether you are an individual or a business you will have our 30 years of insurance broking experience at your disposal, largely gained within the Science and Technology sector.

Commercial Insurance:

We offer tailored insurance products from a range of specialist markets to protect your business assets (including intellectual property) from loss or damage and also against legal liabilities including clinical trials and professional indemnity.

Trade Credit Insurance:

When you finally begin selling your products or services on trade credit, you may wish to speak with us about protection from loss suffered through non payment of invoices by your customers.

Personal Insurance:

We arrange buildings, contents and motor insurance for our clients. This service is not designed to compete with the on-line providers but for those who need wider, more specialised cover. In other words, if you don’t fit into the on-line provider’s tick box then speak to us.

Financial Services:

We are independent – and that is probably important to you. We can offer advice on company and personal matters such as pensions; life insurance; shareholder protection and investment planning. Our expert, industry qualified advisors will be happy to arrange a meeting in the privacy of our offices, your business or your home at a time to suit you.

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55

),6+(5 6&,(17,),& 35(6(176 GE Healthcare GE Healthcare’s broad range of products and services enable healthcare providers to better diagnose and treat cancer, heart disease, neurological diseases and other conditions earlier. Our vision for the future is to enable a new “early health” model of care focused on earlier diagnosis, pre-symptomatic disease detection and disease prevention.

Thermo Scientific Pierce Hyclone Abgene

Researchers looking to make advancements in proteomics now have a powerful ally in Thermo Scientific. New capabilities under the Pierce name create an exciting line of products that include reagents and kits for proteomics research using LC/MS systems.

When combined with Thermo Scientific software solutions, these kits offer sensitive, accurate results that save researchers time and money.

Fisher BioReagents Packaged for convenience in sizes to meet your needs, our superior quality, value-added products are prequalified and guaranteed to be suitable for the designated technique or application.

Ultra-high purity products are supported by stringent specifications detailing critical factors such as water content, levels of contaminants and absence of DNAse, RNAse and protease activity. For higher productivity in your routine research techniques choose Fisher BioReagents.

Terms and Conditions Please note that all sales are subject to our standard terms and conditions. Full details can be found on the inside back cover of our catalogues or visit our website www.fisher.co.uk

Customer Service: 01509 555500 Fax an order: 01509 555111 Order online: www.fisher.co.uk Email: fsuk.sales@thermofisher.com

Fisher Scientific Bishop Meadow Road, Loughborough Leicestershire, LE11 5RG ©2011 Thermo Fisher Scientific Inc. All rights reserved 01888

Your one stop shop for BioReagents and Chemicals Fisher Chemical Manufactured, processed and tested on-site in Loughborough, the Fisher Chemical product range has a clear and simple grade and application structure, making it easy to choose the right product for your requirements.

Acros Organics Acros Organics products are exclusively distributed in the UK by Fisher Scientific.

Over 18,000 organic molecules with detailed product information are available.

Maybridge Maybridge offers a wide variety of premier products and services. The diverse range of building blocks, medicinal chemistry services and renowned screening collections are all available through Fisher Scientific.

Our essential reagents and chemicals enable analysis, research and development, scale-up and manufacturing. The names you can trust are at the foundation of our chemistry solutions.

When you need a product that is not readily available in a chemical catalogue we can help.

Our Specialized Chemical Services team is ready to directly discuss your specific chemical needs including: • Semi-bulk & bulk chemicals • Tailored solvents, blends & solutions • Customized packaging, labelling & testing

Visit

www.wesupportyourchemistry.com

to learn more or request a quote

Helping you manage Projects and Partnerships It’s your People that will make the difference – we help them to drive the most effective teamwork and cross-company collaboration l Assessment,

feedback and coaching Project Teams, Leaders, Alliances/ Partnerships on rapid ways to improve performance l Light-touch modern templates, measurement tools and guidance to

make things work effectively l Leading One Nucleus’ Project Management and Partnering Special Interest Group l We run ‘Essential Project Management’ for One Nucleus and tailored for Companies – high-impact introductory training

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One Nucleus Directory 2012

Pharmidex CSN &ADMET/PK Soltions

The successful translation of basic research results into safe and effective new medicines is the major goal of the pharmaceutical industry.

This is particularly true for CNS medicines, which, compared to non-CNS drugs, take longer to get to market and have a lower probability of getting there. A major contributing factor for the poor translation of neuroscience research into medicines is the high degree of complexity of the human brain, which means that our knowledge of most brain disorders is largely rudimentary. In addition, the brain has a remarkably large demand for energy, which is delivered (in the form of oxygen and glucose in blood) through an intensely arborised network of blood vessels that permits near-instantaneous solute equilibration throughout the brain interstitial fluid (ISF). These blood vessels represent a further challenge for translational CNS medicines research as, unlike blood vessels elsewhere in the body, their endothelial cells form tight junctions. These joined endothelial cells, coupled with astrocytes, pericytes and macrophages, form a barrier that separates brain ISF from blood. It is not just a physical barrier, it also represents a transport barrier, with specific transport mechanisms mediating the egress of compounds out of CNS ISF, and a metabolic barrier, with enzymes metabolizing molecules in transit across the blood-brain barrier (BBB). BBB function is not fixed, and it is modulated and regulated both in physiology and in pathophysiology.

Once a neuroactive compound has moved from the bloodstream into brain ISF, it is available to interact with its molecular target, which is usually a protein: most commonly a membrane receptor or transporter, but enzymes too. Therefore, the concentration of a neuroactive compound in brain ISF over time is a key determinant of the consequent physiological effect (usually receptor antagonism or enzyme inhibition), which leads to a therapeutic effect.

The company also offers a full range of absorption, distribution, metabolism, elimination and toxicity (ADMET) studies of drug candidates to support drug discovery, safety evaluation, and clinical development programs. With a customer base ranging from small biotechnology companies to large pharmaceutical companies, Pharmidex has established itself as a key partner in translational medicines research. On the basis of exemplary levels of commitment, flexibility and value for money, the vast majority of customers (>90%) return for further work.

Tel: +44(0)870 240 5978 Email: business@pharmidex.com www.pharmidex.com

Pharmidex Pharmaceutical Services Limited (Pharmidex) is a contract research organisation that provides high quality assessment of the pharmacokinetic (PK) and blood-brain barrier (BBB) permeation properties of potential drugs, from early discovery projects through to IND. The PK work includes the in-life phase, bioanaltical method development and bioanalysis; the BBB work includes in vitro, ex vivo and in vivo studies.

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Keeping on the Right Side of the Law

by John Dean - Distinctive Publishing

The law, it is said, is a minefield, which is why seeking expert legal advice is crucial in so many situations.

Those people who have tried to save money by dispensing with the services of a solicitor have often found themselves deep in trouble because they ignored that basic mantra.

The reason lawyers are so important lies in the complexity of law, a complexity that is constantly changing.

Take business law: everything from health and safety rules to production legislation can present challenges and a single mistake can lead to a potentially costly breach. The result could be a fine, a court appearance or a large compensation pay-out.

There is also a myriad of law surrounding competition: when is a claim unfair, is a product over-hyped, are the statements made about it correct, is an unfair advantage being taken over a competitor? Or by a competitor?

Patent law is important as well because, once an idea is recognised as unique and owned by one particular individual or company, then it is protected. By registering a product or idea, there is a paper trail which can be used should it turn up elsewhere.

But within the medical sciences field, there is another reason why the law is so important. In a sector where innovation is constantly bringing forward new ideas, companies need to be aware of the legislation governing Intellectual Property (IP) and Patents.

Each and every one of these areas presents great challenges for companies and may require expert legal guidance and so it is always worth seeking out those companies that specialise in the field in question.

IP is crucial because many companies within the industry come up with ideas which are developments of existing science and technology and defining how to protect them is crucial.

That is why understanding IP and knowing how best to register new ideas is important for companies.

More than one company has lost out on millions in profits because they were too slow to register their idea as unique.

Some lawyers specialise in workplace legislation, for instance, others are experts in IP and Patents, others can advise on health and safety and the law relating to contractors.

Each area holds within it the potential to cause a business major problems but by hiring in experts the chances of anything going amiss is greatly reduced.

The basic, overriding message is never mess with the law. Never assume that you know better than the experts, never gamble on the â&#x20AC;&#x2DC;barrack room lawyerâ&#x20AC;&#x2122; who reckons they are right and never leave something till tomorrow that you need to know today.

Ignoring the advice can be as costly as it comes, seeking and taking advantage of it leads to peace of mind and a company that is much more secure.

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One Nucleus Directory 2012

HEALTH PROTECTION

www.onenucleus.com

61

Cell Health Cell Signalling Epigenetics Kinases Proteases Reporter Gene Assay Systems Multiplexing ADME & Metabolism Whole Animal Imaging

Assays for drug discovery and research Starting with a single, well defined biological reaction, Promega has developed a solid technology platform from which hundreds of unique in vitro biochemical and cell-based assays have been configured to provide solutions that enable you to develop better drugs, faster: ͻ ĞƚƚĞƌ ƉƌŽĨŝůŝŶŐ ĚĂƚĂ ͻ DŽƌĞ ďŝŽůŽŐŝĐĂůůLJ ƌĞůĞǀĂŶƚ ĚĂƚĂ ͻ DƵůƚŝƉůĞdžĞĚ ƐŽůƵƚŝŽŶƐ ĨŽƌ ŝŶĐƌĞĂƐĞĚ ƵŶĚĞƌƐƚĂŶĚŝŶŐ ŽĨ ďŝŽůŽŐLJ

Bioassays for Biologics Custom Assay Solutions

ůů KŶĞ EƵĐůĞƵƐ ŵĞŵďĞƌƐ ĞŶũŽLJ Ă ϭϬй ĚŝƐĐŽƵŶƚ ŽŶ ƚŚĞƐĞ ƉƌŽĚƵĐƚƐ͘ All One Nucleus members enjoy a 10% discount on these products.

WůĞĂƐĞ ĐŽŶƚĂĐƚ DĂƩ ŽŽŬ ŽŶ Ϭϳϴϱ ϵϲϮ ϵϬϯ Žƌ ŵĂƩŚĞǁ͘ĐŽŽŬΛƉƌŽŵĞŐĂ͘ĐŽŵ ĨŽƌ ĨƵƌƚŚĞƌ Please contact Matt Cook on 07585 962 903 or matthew.cook@promega.com for further * ĚĞƚĂŝůƐ ĂŶĚ LJŽƵƌ ϭϬй ĚŝƐĐŽƵŶƚ ƋƵŽƚĞ details and your 10% discount quote*

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One Nucleus Directory 2012

16/12/2011 12:04

One Nucleus Corporate Sponsors

A B

Deloitte Stuart Henderson stuhenderson@deloitte.co.uk

C

www.deloitte.com

D

Fax: 01223 259406

E

Tel: 01223 259392

City House, 126-130 Hills Road, Cambridge CB2 1RY

Deloitte is the UK’s fastest growing major professional services firm in 21 locations, with over 10,000 staff nationwide. The Cambridge office of Deloitte boasts an all-encompassing client base with a highly diverse spectrum in terms of industry sector and size of clients, from small start-ups to multinational corporations. 8 Partners and over 200 staff deliver a full range of professional services to the East Anglian region. The Cambridge office has focussed on the opportunities in the technology sector; which the region has been renowned for, and the life and health sciences sector includes a diverse range of businesses. Our Life and Health Sciences practice works with a wide number of clients ranging from some of the most influential multinationals to dynamic new start-ups. To address challenges faced by these organisations we provide a broad spectrum of services spanning audit, tax, corporate finance, strategy, risk assessment and technology advice.

F G H I J

Granta Park Ltd Roz Bird

K

rbird@mepc.com www.mepc.com/grantapark

L M N

Tel: 01223 893710 Fax: 01223 893711 McClintock Building, Granta Park, Great Abington, Cambridge CB21 6GP

The Granta Park Estate is located in the heart of the Cambridge Science Cluster. World leading companies such as Lonza, MedImmune, Pfizer, PPD and TWI have made Granta Park their home and the Riverside development and the McClintock building with accommodation to let are attracting the leading companies of the future. At Granta Park we offer: - A secure, high quality science park environment. - A specialist on site team to work with in order to manage your company?s property requirements now and in the future. - A highly accessible Estate with a green travel plan including a commuter bus service and a location in close proximity to the main transport nodes and trunk roads. - Demonstrable commitment to the sustainability agenda with real practical support for companies looking to achieve and maintain ISO 14001. - Opportunities to be part of a special science community with networking lunches, free meeting facilities, caf‚, gym, nursery and a sport and social programme.

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London First Helen Stewart

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hstewart@londonfirst.co.uk

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Tel: 020 7665 1500

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3 Whitcomb Street, London WC2H 7HA

www.london-first.co.uk

Fax: 020 7665 1501

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London First is a business membership organisation with a mission to make London the best city in the world in which to do business. London First undertakes this by mobilising the experience, expertise and enthusiasm of the private sector to develop practical solutions to the challenges facing London. London First also seeks to persuade central and London government to make the investments that London needs in its infrastructure.

London First delivers its activities with the support of the capital’s major businesses in key sectors such as finance, professional services, property, ICT, creative industries, hospitality and retail. Membership also includes further education colleges and all of London’s universities. London First members represent over a quarter of London’s GDP.

MedImmune Ltd Jon Green greenj@medimmune.com www.medimmune.com Tel: 01223 471471 Fax: 01223 471472 Milstein Building, Granta Park, Great Abington, Cambridge CB21 6GH

A Renowned for our originality and creativity and backed by a 20-year heritage, MedImmune is synonymous with intelligent risk-taking, innovation and entrepreneurial spirit. As AstraZeneca’s worldwide biologics unit, we strive to address unmet medical needs by developing novel proprietary products and cuttingedge technologies. As a result of incorporating translational sciences - otherwise known as “customized medicine” - into some of our programs, MedImmune is continually working towards the future. With two actively marketed infectious disease products and an advancing pipeline of promising candidates in the areas of infection, oncology, respiratory disease and inflammation, cardiovascular/gastrointestinal disease and neuroscience, MedImmune strives to provide better medicines to patients, new medical options for physicians and rewarding careers to employees. We have approximately 3,000 employees worldwide and are headquartered in Gaithersburg, Maryland with facilities in Pennsylvania, California, Kentucky, the United Kingdom, and the Netherlands. UK facilities include vaccine manufacturing operations in Speke and antibody discovery and research laboratories in Cambridge.

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Taylor Wessing Simon Walker swalker@taylorwessing.com www.taylorwessing.com Tel: 01223 446400 Fax: 01223 446401

J Taylor Wessing is a major European law firm with offices in Cambridge, London, Berlin, Brussels, D?sseldorf, Frankfurt, Hamburg, Munich, Paris and Shanghai. It is recognised as a market leader in intellectual property and corporate finance and has considerable expertise in pharmaceuticals and biotechnology having acted for start ups, growing companies, big pharma and big biotech. Solicitors with leading corporate and intellectual property lawyers specialising in advising pharmaceutical and biotechnology companies and venture capital funds.

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24 Hills Road, Cambridge CB2 1JW

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UCB www.ucb.com Tel: 01753 534655 UCB, 208 Bath Road, Slough, Berkshire SL1 3WE

At UCB our sense of purpose is to help people suffering from severe central nervous system or immunological disorders lead normal, everyday lives. Our ambition is to offer them innovative new medicines and ground-breaking solutions that go beyond the drug. We are committed to enabling cuttingedge scientific research that is driven by the patients’ needs. UCB, headquartered in Belgium, is a global biopharma company with a team of 8500 talented employees, a strong market presence in more than 40 countries, 3.2 billion in revenue and numerous strategic partnerships. Slough is home to UCB’s R&D and UK Commercial & Corporate functions, employing 600 staff.

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World Courier (UK) Ltd Abigail Bradley abradley@worldcourier.co.uk

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www.worldcourier.com

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Fax: 020 7928 7105

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Tel: 020 7717 1400

8th Floor, Sea Containers House, London SE1 9PD

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The shipment of infectious or diagnostic biological samples and clinical trial supplies requires expert handling. World Courier is a pioneer in the transport of sensitive medical and pharmaceutical shipments, delivering the first human heart tissue for transplant in 1984. Specialising in the transport of temperature controlled and time critical samples; World Courier is committed to handling every consignment on an individual, priority basis. This translates into a premium service where our experienced staff ensures that your shipment arrives on time and in perfect condition. With in-house scientists to understand your needs, World Courier can recommend and provide appropriate packaging and refrigerants to ensure the integrity of your temperature controlled shipment. Documentation and regulatory requirements are managed by World Courier to ensure your shipment complies with country requirements. Your shipment is dispatched on the first available flight and actively monitored throughout its journey. Confirmation of the delivery is provided immediately upon arrival. World Courier Goes Public with Network-wide GxP Compliance - An Industry First! This status applies strictly to the transport side of the business, but, when combined with our GMP-compliant network of investigational drug storage depots (CTSCS), allows World Courier to deliver a fully GxP-compliant transport and storage supply chain system to biopharm customers - a feat that is unparalleled in the industry and once again clearly sets us apart from competitors.

One Nucleus Partners

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Babraham Research Campus Derek Jones info@babraham.co.uk www.babraham.com Tel: 01223 496269 Fax: 01223 496020 Babraham Research Campus, Cambridge CB22 3AT

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The Babraham Research Campus, home to both world-class academic research and commercial biomedical companies, has established itself as one of the UK’s leading enterprise hubs of bioscience innovation. Situated on a 450 acre estate six miles south of Cambridge, the campus has an ideal geographical location at the heart of the Cambridge biomedical cluster, close to many world-leading academic research centres such as the MRC Laboratory of Molecular Biology (LMB), the Wellcome Trust Sanger Institute, Cancer Research UK and the University of Cambridge. At the cornerstone of the campus is the Babraham Institute, which receives strategic funding from the BBCRC and undertakes international quality life sciences research to generate new knowledge of biological mechanisms underpinning ageing, development and the maintenance of health.

The campus Bioincubator offers bespoke, state-of-the-art research and development facilities, scientific support services for bioventures at any stage in the business development cycle and supports the full spectrum of science from R&D to commercial realisation. Companies have access to the Technology Development Laboratory, set up by Babraham Bioscience Technologies (BBT) Ltd – the Institute’s commercial arm, as a place to accelerate the translation of early-stage concepts in the life science and biomedical fields. BBT also has the responsibility for Knowledge Exchange and Commercialisation of the Institute’s research, facilitating industry collaborations, patents and licensing agreements.

London BioScience Innovation Centre (LBIC) Ken Larkin klarkin@rvc.ac.uk www.lbic.com

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Tel: 0207 691 2076

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2 Royal College Street, London NW1 0NH

Fax: 020 7419 5983

LBIC is London’s premier incubator for life science companies, owned and managed by the Royal Veterinary College. LBIC supports over 45 companies ranging from entrepreneurial start-ups to more established UK businesses and overseas subsidiaries. Our clients benefit from flexible terms, an extensive range of support services and access to Category II laboratories, office suites, meeting rooms and conference facilities. LBIC also offers a virtual package for companies seeking a visible presence in London at minimal risk to the business.

LBIC is 10 minutes walk from St Pancras International for Eurostar services and the site of the new Francis Crick Institute.

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Queen Mary Bioenterprises Ltd

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Simone Reid

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www.qmbioenterprises.com

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42 New Road, London E1 2AX

simone.reid@qmul.ac.uk

Tel: 0207 882 8950

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The QMB Innovation Centre (“QMB “) based in London E1 is an incubation and follow-on space for existing science and technology companies looking to expand, or start-up companies and later stage companies seeking an entrepreneurial base for their laboratory and commercial work.

QMB has in total capacity 39,000 sq ft of modern, laboratory and office space. It is situated on the research campus of Bart’s and The London School of Medicine and Dentistry, providing tenants with a wealth of local advice and expertise.

The QMB Innovation Centre is the largest and only centre to offer follow-on laboratory space in London. It also offers reconfigurable laboratory and write-up space and flexible leases.

The QMB Innovation Centre hosts Investment Forums where companies are invited to pitch to our network of investors and attend as part of their partnering activity. These forums are the highlight of the events calendar, with companies, business support advisors and investors attending from all over the world.

QMB has an extensive service provider network to support tenant companies, which has recently been formed and will continue to be expanded

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University College London Business PLC Anne Lane a.lane@uclb.com www.uclb.com Tel: 020 7679 9000 Fax: 020 7679 9838 The Network Building, 97 Tottenham Court Road, London W1T 4TP

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One Nucleus Gold Members

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Abcam plc www.abcam.com

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Abcam is a producer and distributor of high quality research-grade antibodies and associated proteomics research products; antibodies are essential tools for life scientists that enable them to analyse components of living cells at the molecular level. Since it was founded in 1998 by Dr. Jonathan Milner, Abcam has enjoyed rapid growth and is widely accredited as a leading company in its industry, with annualized turnover in excess of £60 million and growing. Headquartered in Cambridge (UK), Abcam has subsidiaries in Cambridge (US), Tokyo (Japan) and Hong Kong (China), allowing them to serve a global customer base of over 75 countries. Abcam revolutionized the buying of antibodies via its website and their online catalogue consists of tens of thousands of products, supported by hundreds of thousands of pages of accompanying data. This includes a growing range of non-antibody products such as proteins, peptides, lysates, immunoassays and other kits, which will continue as the business expands in the broader protein detection and regulation market. A key component in the success of Abcam comes from the speed with which it can bring products to market and it’s customer support efficiency.

This enables scientists to find products with specific characteristics quickly, thus speeding up the pace of research into important diseases such as cancer and coronary heart disease. Abcam’s in-house expertise means they are able to source products and supplementary resources for the newest and fastest growing research areas like Cancer, Cardiovascular, Chromatin, Immunology, Neuroscience and Stem Cells. For further information, visit www.abcam.com

Alacrita Anthony Walker awalker@alacritaconsulting.com www.alacritaconsulting.com Tel: 020 7691 4915

Alacrita provides expertise-based consulting services to the pharmaceutical, biotechnology and life science sectors. We combine extensive industry experience and broad functional capabilities to help our clients create sustainable value, providing: flexible managerial support, ranging from a single individual on a part time basis through to an entire management team. multidisciplinary project teams to conduct specific assignments;instant expertise: high-level strategic, commercial and technical; Alacrita’s team has industry experience and a consulting track record, ensuring that projects are delivered with both professionalism and real-world relevance.

The London Bioscience Centre, 2 Royal College Street, London NW1 0NH

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Amgen Limited

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Tel: 01895 525000 0800 243104

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Fax: 01895 525100 Amgen Limited, 1 Uxbridge Business Park, Sanderson Road, Uxbridge UB8 1DH

Amgen discovers, develops and delivers innovative human therapeutics. A biotechnology pioneer since 1980, Amgen was one of the first companies to realize the new science’s promise by bringing safe, effective medicines from lab, to manufacturing plant, to patient. Amgen therapeutics have changed the practice of medicine, helping millions of people around the world in the fight against cancer, kidney disease, rheumatoid arthritis, and other serious illnesses. With a deep and broad pipeline of potential new medicines, Amgen remains committed to advancing science to dramatically improve people’s lives. To learn more about our pioneering science and our vital medicines, visit www.amgen.co.uk

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Antitope Ltd Neil Butt, Business Development Director

Antitope is pioneering a new generation of immunogenicity testing, antibody humanization and protein engineering technologies.

www.antitope.com

Their mission is to apply these technologies to create improved non-immunogenic biologics. Formed in 2004, Antitope provides proprietary technologies as a comprehensive service for the preclinical prediction of clinical immunogenicity, and for the generation of humanized antibodies, therapeutic proteins and recombinant vaccines.

To date, they have entered into multiple agreements with pharmaceutical and biotechnology companies worldwide to apply their technologies for the development of improved biologics.

Tel: 01223 496190

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Argenta Discovery 2009 Limited argenta@glpg.com www.argentadiscovery.com Tel: 01279 645645 A Galapagos Company, 8-9 Spire Green Centre, Flex Meadow, Harlow, Essex CM19 5TR UK

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Argenta is an integrated drug discovery contract research organisation based in Harlow, UK. We are part of the Galapagos group of companies, Europe’s largest drug discovery contract research organisation. Argenta is a trusted strategic partner with over 10 years experience in small molecule drug discovery and offers an integrated approach to complete drug discovery programmes as well as hit identification, hit to lead, and lead optimisation projects. Argenta has discovered an industry-leading number of development candidates for its clients. As well as complete projects, Argenta offers individual services on a fee-for-service basis, these include; biomarker identification, ADME, solid-state chemistry, process/scale-up chemistry and candidate de-risking services.

Argenta is a successful and growing organisation that provides a high-quality, high-value service, and one able to contribute significantly to the generation of intellectual property. Ours and our clients’ success is a consequence of a focus on drug discovery expertise, achieved through our recruitment of exceptional scientists. Indeed Argenta scientists boast an average of over 16 year’s relevant drug discovery expertise.

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Asterand Zuleika Roberts zuleika.roberts@asterand.com www.asterand.com Tel: 01763 211600 2 Orchard Road, Roystonm, Hertfordshire SG8 5HD

Asterand is the leading global supplier of high quality, well characterized human tissue and human tissuebased research services to support drug discovery & development. We provide human based solutions to pharmaceutical and biotechnology companies to accelerate the identification and validation of drug targets and enhance the selection of drug candidates with an increased likelihood of clinical success.

Asterand has a significant and well established human tissue heritage, having been formed through the combination of three leading human tissue focussed organisations.

Asterand offers unparalleled access to human tissues for research through its worldwide network of collaborative donor institutions. Asterand’s Services division offers exemplary scientific expertise in collaborative human tissue research. Our PhaseZERO® platform delivers human tissue-based data supporting target & biomarker validation and compound function & safety. Our BioMAP® platform, comprising a comprehensive panel of automated, human primary cell based disease systems, enables rapid input on mechanism of action, efficacy and side effect profiles of drug candidates, providing actionable data to guide lead selection and optimisation.

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Astex Pharmaceuticals Inc

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Jeremy Carmichael, Director of Business Development

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info@astx.com www.astx.com Tel: 01223 226200 2 Orchard Road, Royston, Hertfordshire SG8 5HD

Astex Pharmaceuticals, Inc. is an international, NASDAQ-listed (ASTX) pharmaceutical company dedicated to the discovery and development of novel therapeutics with a focus on oncology. The Company’s proprietary pipeline of drugs is de-risked as a prelude to partnerships with leading pharmaceutical companies. Astex Pharmaceuticals was formed out of a merger between SuperGen and Astex Therapeutics with locations in Dublin, CA and Cambridge, UK. Astex Pharmaceuticals receives significant royalties on global sales of Dacogen® (decitabine) for Injection, a marketed drug developed by the company. In 2011, royalty revenue is forecasted to exceed $61million. Eisai and Janssen, the global marketers of Dacogen, have filed for approval of a new indication in both the US and EU. Astex Pharmaceuticals has a broad portfolio with four clinical programs that are expected to provide phase II proofof-concept data in 2012. Two of the programs, AT13387, an HSP90 inhibitor, and SGI110, a second generation hypomethylating agent, will be expanded in 2012 to test clinically additional indications. Astex has partnered development programs and ongoing collaborations with pharmaceutical companies including J&J, GSK, AZ and Novartis that could generate more than a billion dollars in milestone revenue as products and projects progress.

Astex is a recognized world leader in fragment-based drug discovery and uses its proprietary technologies to generate new drug candidates across multiple therapeutic indications. The fragment-based approach to drug discovery has been shown to be successful at identifying small molecules with optimal drug-like properties against difficult targets.

For more information about Astex Pharmaceuticals: http://www.astx.com.

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Beckman Coulter Genomics Liz Bland EBland@beckman.com www.beckmangenomics.com Tel: 01279 873837 Hope End, Takeley, Essex M22 6TA

Beckman Coulter Genomics is a leading provider of genomic services, serving life-science researchers and pharmaceutical industries throughout the world. By providing technical expertise, combined with personalized service, Beckman Coulter Genomics delivers the highest quality data, robust analyses and innovative thinking. Beckman Coulter Genomics has expertise and experience on a wide range of genomic technology platforms and is dedicated to delivering the highest quality results across the extensive range of genomic services provided. Beckman Coulter Genomics services include: Sequencing Beckman Coulter Genomics offers a comprehensive range of sequencing services for individual samples, high-throughput projects and custom strategies using both Sanger and next generation technologies, enabling high quality data generation for diverse applications. Services include whole genome and transcriptome analysis, targeted resequencing and metagenomics.

Genotyping Beckman Coulter Genomics use multiple platforms in support of a comprehensive genotyping offering including clinical genotyping, genome-wide association, chromosome copy number, linkage analyses and population genetic studies. Gene Expression Profiling For profiling across multiple platforms, Beckman Coulter Genomics have a suite of gene expression tools. Our experienced team of molecular and computational biologists enables you to fully incorporate transcript profiling into target prioritization and validation, lead screening, toxicity profiling, mechanism of action and pre-clinical/clinical studies. Biologics Testing Beckman Coulter Genomics offers a group of services aimed to evaluate the identity, stability, purity, and safety of biological products. These services are compliant with GLP/cGMP regulations and include microbial detection/differentiation, cell bank characterization, residual DNA analysis and biodistribution studies.

www.onenucleus.com

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Bicycle Therapeutics Limited Dr John Tite, CEO

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johntite@bicycletherapeutics. com

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www.bicycletherapeutics.com

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Meditrina Building, Babraham Research Campus, Babraham, Cambridge CB22 3AT

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Tel: 01223 497390

Bicycle Therapeutics is a biotechnology company based at the Babraham Research Campus in Cambridge, U.K. developing a novel technology which uses biological selection methods to identify molecules which combine features of small molecular weight drugs and and biopharmaceuticals. The technology allows the identification of highly constrained peptides with high potency and selectivity against the target of interest. Bicycle peptides have properties that overcome many of the deficiencies of previous generations of peptide based drugs and the Bicycle libraries offer a vast diversity with which to interrogate target space. Bicycle technology is based on the work performed at the MRC Laboratory of Molecular Biology in Cambridge by the scientific founders of the company, Prof. Christian Heinis and Sir Gregory Winter. The company was founded in July 2009 and received initial seed funding from Atlas Venture and Novartis Venture Fund who were subsequently joined by SVLS and SR One to complete the seed phase syndicate. For more information visit www.bicycletherapeutics.com

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Biocaldol Limited info@biocaldol.com www.biocaldol.com Tel: 0207 6914912 Fax: 0207 6819129 London Bioscience Innovation Centre, 2 Royal College Street, London NW1 0NH

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BioFocus

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Dr Roland Bürli

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www.biofocus.com/

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BioFocus, Chesterford Research Park, Saffron Walden, Essex CB10 1XL

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biofocus@glpg.com

Tel: 01799 533500

Biocaldol Ltd. specialises in developing turnkey solutions designed to transform the agro-industry.

These solutions comprise proprietary, environmentally-friendly micro-organisms, custom-made process design and engineering for the production of second-generation biofuels, animal feed and other biomass-derived products.

Biotechnology Conversion Technology Ltd (BCTL), a research and development arm of Biocaldol, was founded in 2003 to focus on the development of a thermophilic (high temperature) bioethanol (ethyl alcohol) production process. Its internationally patented and ground-breaking fermentation technology for producing bioethanol from plant waste and residues overcomes barriers related to the acceptance and commercial production of bioethanol.

The Biocaldol’s technology is based on proprietary microorganisms and is designed to convert the world’s vast and largely under-utilised lignocellulosic biomass resources into renewable motor vehicle biofuel (bioethanol) and other high value industrial chemicals.

Short-term, the business is expected to demonstrate cost benefits of at least 50% over current ethanol processes and deliver further cost savings for ethanol producers through the modular and standardised designs.

The current focus of Biocaldol business is system integration. Using its innovative technology, processes and microorganisms, Biocaldol can maximise customers’ ethanol production output.

Biocaldol works closely with customers and agro-industrial partners to retrofit conventional ethanol plants, develop process components and engineering expertise and marketing access within the potential market sectors. Through this unique technological approach the high cost of capital associated with conventional processes is avoided

BioFocus provides integrated drug discovery that delivers pre-clinical drug candidates in all therapeutic areas with strong capability in neurodegenerative diseases, inflammatory diseases and with a growing track record of delivering candidates against rare and neglected diseases. BioFocus has advanced and comprehensive drug discovery capabilities that are applied to client projects to deliver targets, hits, leads and candidate pre-clinical drugs. The company employs over 220 exceptionally qualified and industry experienced scientists at its three research centers in the UK, Switzerland and the Netherlands. Since its foundation in 1997, BioFocus has striven to produce high quality data for its clients and this quality is assured by ISO9001 qualification validated by regular, independent inspection of all BioFocus research centers. For more information visit www.biofocus.com

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Biotechnology Industry Organization (BIO) www.bio.org 1625 K Street, NW Suite 1100, Washington DC 20006-1604 USA

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BIO members are involved in the research and development of innovative healthcare, agricultural, industrial and environmental biotechnology technologies. Corporate members range from entrepreneurial companies developing a first product to Fortune 100 multinationals. We also represent state and regional biotech associations, service providers to the industry and academic centers. Visit the BIO Member Directory to browse BIO members and Web site links as well as BIO state and international affiliates. Member services include: * Federal and state advocacy on issues affecting the industry * A dozen or more investor and partnering meetings throughout the year, with discounts for members * Communications services that disseminate information about the benefits of biotechnology * BIO Business Solutions discounts for a variety of goods and services Specific issues may have changed over the years, but our core mission of fostering biotechnology innovation through advocacy, business development and communications remains the same. BIO produces the annual BIO International Convention, the world’s largest gathering of the biotechnology industry. The BIO International Convention attracts more than 20,000 attendees from around the world including more than 500 members of the international press.

Convention attendees hear from global biotechnology leaders, learn about the latest biotech innovations and network with their peers from established and emerging biotech companies, research institutions, service providers and biotech hubs.

BIO also produces a series of industry-leading investor and partnering meetings held around the world.

Biotica Technology Ltd info@biotica.com www.biotica.com Tel: 01223 890539 Riverside 3, Suite 5, Granta Park, Great Abington, Cambridge CB21 6AD

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Biotica is a Cambridge (UK) biotechnology company focused on identifying novel therapeutics based on polyketides. The company uses its proprietary biosynthetic engineering platform to identify novel polyketides, with improved pharmaceutical benefits, which could not be made using medicinal chemistry approaches.

The company has implemented partnerships based on differentiated compounds derived from its technology platform, including the following: Pfizer and Biotica are developing novel analogs of the immunosuppressant drug, rapamycin, in new indications. GSK and Biotica are collaborating to discover and develop novel erythromycin macrolides for treatment of inflammatory disease. There are more than 40 marketed polyketide therapeutics, including the statins, erythromycin, rapamycin and FK506. Six polyketide drugs have each achieved annual sales in excess of $1 billion. Polyketides are a successful drug class because they have diverse and complex chemical structures, resulting in important biological properties which are not attainable using synthetic small molecules.

Biotica has developed a competitive advantage in the discovery of polyketide therapeutics. The company’s business model is to integrate with partners that have extensive therapeutic biology and other complementary capability. Biotica’s approach represents a transformational opportunity to discover a new generation of engineered polyketide therapeutics.

www.crbdiscovery.com Tel: 01642 567180 Fax: 01642 567181 10 Belasis Court, Belasis Hall Technology Park, Billingham, Cleveland, TS23 4AZ

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Cambridge Research Biochemicals (CRB) info@crbdiscovery.com

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Cambridge Research Biochemicals (CRB) celebrates over 30 years of providing custom-made research tools to the Life Science community. The company, founded in 1980 is the second oldest peptide company in the world and specialises in everything peptide from design to synthesis, modification and labelling. In addition, we generate target specific antibodies to novel proteins and their peptide surrogates. Our chemical expertise is further applied to fluorescent labelling of peptides, antibodies and proteins and we can advise on appropriate fluorescent dyes for FRET and other fluorescence based applications. Our business works in partnership with other complementary specialist businesses or research institutes to extend our portfolio to offer: unique Fluorescent dyes; Monoclonal antibody production; Chemistry services; Radiolabelling and PNA synthesis. CRB enjoys longstanding relations with top ten pharmaceutical companies and world renowned research institutes.In 2009, CRB was granted EC support of 196,400 Euros as a contributing SME partner in the FP7 BIOSCENT R&D project for providing peptide design and synthesis expertise to develop self-assembling peptides within the context of biomaterials for heart patches. This followed shortly after a Capital Expenditure programme worth quarter of a million pounds to expand and advance the peptide and immunology operations supported by One NorthEast Development Agency. The company is privately owned by two female directors who were winners of the North-East Women Entrepreneur Awards.

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Cantab Biopharmaceuticals Ltd

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Dr Jim Mills, CEO

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jim.mills@cantabbio.com www.cantabbio.com Tel: 01223 423413 150-155 Cambridge Science Park, Milton Road, Cambridge CB4 0GN

Cantab Biopharmaceuticals Ltd (CBL) is a drug development company focused on the development of “biosuperior” products. Cantab is based in Cambridge, UK at the heart of the largest biotech cluster in Europe.

The company uses its extensive experience in biopharmaceutical discovery, process development and GMP manufacturing to expedite the development of biosuperiors from inception through clinical development. The strategy of the company is to add value to previously marketed, off-patent, biologics by applying cuttingedge technologies that address sub-optimal characteristics of the marketed product. Particular areas of drug characteristics that Cantab seek to improve upon are product presentation and stability, pharmacokinetics, pharmacodynamics, immunogenicity and drug delivery.

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Cell Guidance Systems Michael Jones, CEO michael.jones@cellgs.com www.cellgs.com Tel: 01223 497115 Babraham Research Campus, Cambridge CB22 3AT UK

Cell Guidance Systems commercializes innovative technologies to accelerate and enable stem cell science.

We are focussing on (1) the culture of human pluripotent stem cells and (2) the development of highly active, potentiated growth factors. Pluripro® media allows the culture of human pluripotent cells in a confluent monolayer which is amenable to automation and scale-up. STARTM growth factors utilize a hyaluronic acid backbone to tether and coordinate cell receptors binding. Tethering results in biological activity in the range10100 fold higher than standard growth factors. Both of these technologies are now being marketed and address significant existing and potential global markets. Cell Guidance Systems has offices in Cambridge, UK and San Diego, California.

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Cellzome Limited Richard Hale richard.hale@cellzome.com www.cellzome.com Tel: 01799 532800 Chesterford Research Park, Little Chesterford, Cambridge CB10 1XL

Cellzome is a world leader in chemoproteomics, transforming the sciences of epigenetics and signal transduction into novel drug candidates in inflammatory diseases and oncology. The Company maintains the highest levels of scientific expertise and has active collaborations with the foremost academic laboratories around the world.

Cellzome’s technologies work with native proteins in a physiological setting to discover small molecule drugs targeting protein complexes that underlie diseases. The Company has a track record in delivering significant collaborations with top pharmaceutical companies including GlaxoSmithKline, Johnson & Johnson and Novartis.

Cellzome is an international company located in Heidelberg, Germany and Cambridge, UK employing about 100 people.

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Convergence Pharmaceuticals Ltd Brenda Reynolds, Chief Operating Officer info@convergencepharma.com www.convergencepharma.com

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Tel: 01223 755501

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Maia Building, Babraham Research Campus, Cambridge CB22 3AT

Convergence Pharmaceuticals is an independent biotechnology company focused on the development of novel analgesics. The Company was formed in October 2010, following the acquisition of certain neuroscience clinical assets from GlaxoSmithKline, and is well funded having raised $35.4 million in Series A financing from leading European and US financial institutions. It has a pipeline of differentiated clinical-stage compounds targeting the points of convergence in chronic pain signalling through modulation of specific ion-channels.

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Crescendo Biologics

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Amanda Bettison

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www.crescendobiologics.com

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Meditrina Building 260, Babraham Research Campus, Cambridge CB22 3AT

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info@crescendobiologics.com

Tel: 01223 497140

Crescendo Biologics is a Cambridge-based company whose aim is to deliver next-generation antibody therapeutics based on novel class-leading platforms. The company is focussed on developing a transgenic mouse platform for in vivo generation of human, high-affinity, soluble, VH antibody fragments. These are the smallest fragments that retain antibody binding and have many desirable properties as potential therapeutics.

Crescendo will utilise this platform for product development of in-house targets or in partnership with other companies. Crescendo is led by a management and Board with exceptional experience in the antibody field and the biotechnology sector, backed by a syndicate of leading life science investors.

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Cresset BioMolecular Discovery Ltd Rachel Richardson rachel@cresset-group.com www.cresset-group.com Tel: 01707 356120 Fax: 01707 356118

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Biopark Hertfordshire, Broadwater Road, Welwyn Garden City, AL7 3AX

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Cresset makes software for calculating and comparing the molecular Field characteristics of chemical compounds. Field technology uses the surface properties of molecules to evaluate their activities and properties, rather than relying on 2D structure similarity, which enables Cresset’s users to find more interesting, novel and relevant results than other methods. Cresset’s Fields provide a smarter, structure independent way of hit-finding, lead switching and lead optimization in drug discovery and other chemistry-based research projects. Cresset’s software and services have been successfully applied to a very wide range of target classes, with and without structural information, on over 100 projects for major pharmaceutical and biotechnology companies around the world. www.cresset-group.com

Cyclofluidic Ltd Elizabeth Farrant elizabeth.farrant@cyclofluidic. co.uk www.cyclofluidic.co.uk Tel: 01707 358706 BioPark, Broadwater Road, Welwyn Garden City, Hertfordshire AL7 3AX

A Cyclofluidic is an emerging technology company that has developed a fully integrated approach to the synthesis and screening of small molecules for drug discovery. Small molecule lead discovery typically involves an iterative process of molecular design, chemical synthesis, biological assay and analysis to feed into the next learning cycle. Using conventional approaches, each learning cycle in this process may take between 1 and 8 weeks, depending on where compounds are made and tested leading to slow and expensive hit to lead exploration with a limitation the number of hit series that can be assessed. In addition, compounds are often designed and made “at risk” i.e. without incorporating the latest data from the previous design cycles, leading to wasted effort and resource. The Cyclofluidic technology platform integrates all these processes allowing drug lead molecules to be assayed minutes rather than weeks after they are designed. Potential lead molecules are synthesised, purified and screened in fast serial mode, incorporating activity data from each compound as it is generated before selecting the next compound to make. Cyclofluidic has now demonstrated this fully integrated process and the real advantages that it can bring to discovery projects. The company is now actively pursuing collaboration opportunities to enable partners to benefit from the advantages of a fully integrated approach to the generation of structure activity relationship (SAR) data within their medicinal chemistry projects. Cyclofluidic operates out of very well equipped laboratories within BioPark, Welwyn Garden City with an exceptional technical and management team.

probes@cytocell.com www.cytocell.com Tel: 01223 294048 Fax: 01223 294986 3 – 4 Technopark, Newmarket Road, Cambridge, Cambridgeshire CB5 8PB

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Cytocell Limited Martin Lawrie

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Cytocell Ltd. is a leading European developer and manufacturer of FISH probes for use in both routine cytogenetics and in the analysis and classification of Cancers. The Company’s products are well established in Cytogenetics as the Company has recently celebrated its 20th year of supplying them to this market. More recently, the Company has focused on developing products for Oncology and now has a catalogue of some 300 products for Cytogenetics, Haematology and Solid Tumour analysis as well as developing custom FISH probes for customers with specific interests under the myProbes® brand. Cytocell’s products are available through a well established distributor network, covering more than 60 countries worldwide. Cytocell’s FISH probe service is currently proving to be invaluable to cancer researchers and clinicians worldwide.

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DeltaDot info@deltadot.com www.deltadot.com Tel: 020 7691 2075 London BioScience Innovation Centre, 2 Royal College Street, London NW1 0NH

deltaDOT is an Imperial College spin out that has developed its PEREGRINE I instrument for the separation and analysis of biomolecules such as proteins, nucleic acids, viruses and bacteria, small molecules such as drugs and chemicals and a wide range of other analytes. The PEREGRINE I uses an advanced form of Capillary Electrophoresis that deltaDOT has developed. This new approach results in faster, higher quality results at a fraction of the cost of conventional approaches.

Other key advantages of this new approach include accurate quantitation of biomolecules and excellent reproducibility.

As a result of the improved data quality that the PEREGRINE I produces, many uses of our technology have been found (for example in QA/QC applications such as stability studies, and batch-to-batch comparisons). deltaDOT currently has 8 employees and recently moved to LBIC. In addition to selling instruments deltaDOT also offers an analytical service.

If you are looking to outsource your analytical workloads then please contact us to discuss your requirements. We seek contract research opportunities and collaborations in the pharmaceutical and biotechnology sectors. Benefits include shorter R&D timescales and reduced analytical costs associated with traditional CE and other techniques such as HPLC and mass spec. In particular, significant cost savings from deltaDOT’s technology may be available to biopharmaceutical manufacturing companies. Enquiries from global players looking to distribute our PEREGRINE I instrument would be welcome. We are also interested in discussing the licensing of our technology with instrument manufacturers. For further information please visit www.deltadot.com or call us.

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Domainex Ltd enquiries@domainex.co.uk www.domainex.co.uk Tel: 01223 743170 162 Cambridge Science Park, Milton Road, Cambridge CB4 0GH

Domainex is a drug discovery company with a reputation for speed and innovation built on an exceptional track record of drug candidate delivery. It has a world class discovery team with an unrivalled track record and three client drug candidates already in the clinic. Domainex reduces industry average drug discovery timelines by as much as 30% through the application of novel proprietary technologies and a highly focussed and integrated approach to medicinal chemistry and computational chemistry. These technologies and Domainex’s approach also enable it to successfully tackle a greater range of drug target classes, such as kinases, proteases, ion channels, proteins involved in epigenetics and protein-protein interactions. Domainex has applied its unique technologies and focussed discovery approach to enable it to develop its own pipeline of oncology drugs, including inhibitors of the kinases IKK?/TBK1 and a number of epigenetics related lysine methyltransferases. Domainex’s technology and service offering includes: • Combinatorial Domain Hunting (CDH); a proprietary technology for the expression of protein drug targets for structural studies and the selection of ligand binding protein constructs for use in assay design • Development of biochemical binding or activity assays for use in compound screening • LeadBuilder: hit identification technology, for the extremely fast and reliable identification of hit-like and developable compounds against the target of interest • Integrated medicinal and computational chemistry services, with a superb track record in the delivery of Candidate Drug • Advice and leadership during your drug discovery projects • DMPK testing support

www.onenucleus.com

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Dr Reddy’s chirotechenquiries@drreddys.com www.drreddys-cps.com Tel: 01223 72 80 10 Fax: 01223 50 67 01 Chirotech Technology Limited, 410 Cambridge Science Park, Milton Road, Cambridge CB4 0PE United Kingdom

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Eagle Genomics Ltd info@eaglegenomics.com

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www.eaglegenomics.com

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Fax: 01223 281125

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Custom Pharmaceutical Services (CPS) is a strategic business unit of Dr Reddy’s and has emerged as one of the major pharmaceutical service providers from India. Our manufacturing and dedicated R&D facilities across three locations worldwide (UK, India and Mexico) offer a wide range of services, years of experience and an undeniable expertise in pharmaceutical development.

Recent investment in the UK has seen our Cambridge Chirotech facilities now expand to 30,000ft2 and our substantial Mirfield API cGMP manufacturing plant is also increasing in capacity to meet the ever growing customer demand.

Our world class infrastructure is ready to support our customers from early kg-scale to multi-tonne scale commercial manufacturing of intermediates, APIs and final drug product to serve global pharmaceutical and biotech companies’ outsourcing needs cost effectively and reliably.

CPS also specializes in novel technologies that add value to customer’s development and manufacturing projects.

These specialized technologies can provide benefits such as new IP, greater speed, heightened safety, and cost containment resulting in levels of success for our customers that would not otherwise be possible.

CPS is one of the few service providers to offer complete solutions for: Highly Potent APIs and Cytotoxic Formulations, Chiral Products and Technologies, Steroids, PEGylation, Dosage Specialties. Partner today with CPS and discover why our company heritage of more than 25 years in pharmaceutical development makes us the ideal strategic partner for your business!

Tel: 01223 654481

Babraham Research Campus, Cambridge CB22 3AT

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Eagle Genomics is a bioinformatics services and software company specialising in the provision of outsourced genome content management and delivering open-source solutions. Eagle supplies quality outsourcing solutions for customers across the biotech sector and beyond. We combine cloud and Next Generation Sequencing (NGS) expertise with a track record in building scalable, efficient genomics analysis workflows using both commercial and open source software. Open-source bioinformatics software gives you unparalleled access to the very latest algorithms, data and techniques to use in your R&D. However, it can be hard to obtain timely technical support when things don’t go quite to plan. This can cost you time and money from lost productivity. Eagle Genomics provides that support. For a range of open-source bioinformatics technologies we guarantee our response times and provide you with fixes and customisations. This saves you time and effort, and helps minimise the cost of your projects. Eagle is extremely flexible in the ways we can work with you. Whether you are in pharma, biotech, CRO or a university research group, we provide exactly what you need to make the most of bioinformatics software.

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Essen BioScience Ltd

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Tim Dale

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www.essenbioscience.com

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Fax: 01707 358687

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dale@essenbio.com

Tel: 01707 358688

Essen BioScience Ltd, BioPark, Broadwater Road, Welwyn Garden City, Herts AL7 3AX

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f-star GmbH office@f-star.com www.f-star.com Tel: 01223 896350 The Portway, Granta Park, Cambridge CB21 6GH

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Essen Bioscience is a leading instrument and service provider in the life science research field, specialising in innovative cell-based assays. Products invented by Essen personnel include the first high-throughput cell-based assay platform, FLIPR; the first high-throughput planar electrophysiology platform on the market, IonWorks and the first live-cell imaging system to fit inside a standard cell culture incubator, IncuCyte. Our discovery services division deploys these and other technologies in providing bespoke solutions for our pharma, biotech and academic client base.

Genzyme Therapeutics Ltd www.genzyme.co.uk Tel: 01223 394000 Fax: 01223 394190 310 Cambridge Science Park, Milton Road, Cambridge CB4 0WG

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One of the world’s leading biotechnology companies, Genzyme is dedicated to making a major positive impact on the lives of people with serious diseases. Since its founding in 1981, the company has introduced breakthrough treatments across several areas of medicine that have provided new hope for patients. Today, approximately 10,000 Genzyme employees serve patients in nearly 100 countries. Genzyme’s products are focused on rare inherited disorders, kidney disease, orthopaedics, cancer, transplant, and immune disease. The company’s commitment to innovation continues today with a substantial development program focused on these fields, as well as cardiovascular disease, neurodegenerative diseases, and other areas of unmet medical need.

Genzyme is part of the Sanofi Group. Genzyme in the UK Over the past eight years Genzyme has made capital investments in the UK totalling more than £115 million. Genzyme in the UK employs in the region of 500 people in research, development as well as commercial manufacturing and distribution roles. Genzyme UK comprises three different sites; Oxford, Haverhill and Cambridge.

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Gilead Sciences Ltd www.gilead.com Tel: 01223 897300 Granta Park, Great Abington, Cambridge CB21 6GT

Gilead Sciences is a research-based biopharmaceutical company that discovers, develops and commercialises innovative medicines in areas of unmet need. With each new discovery and experimental drug candidate, we seek to improve the care of patients suffering from life-threatening diseases. Gilead’s primary areas of focus include: antivirals (such as HIV/AIDS and chronic hepatitis), cardiovascular conditions (such as pulmonary arterial hypertension and resistant hypertension) and respiratory diseases (such as influenza and cystic fibrosis). Gilead Sciences has grown from one facility in California to 19 sites with more than 2,900 employees in 15 countries across North America, Europe and Australia. Outside of North America, we have offices in 15 European countries and Australia. Our European headquarters are located in Stockley Park, outside London, in the United Kingdom.

Gilead plans to open additional commercial operations in Europe in the coming months. We have created a network of exclusive distributors that work to ensure access to our commercial products in many parts of the world. These distributors currently support Gilead products in more than 40 countries across Eastern Europe, Scandinavia, the Middle East, Asia, Africa and Latin America

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Horizon Discovery Ltd

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Shane Pereira

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shane.pereira@horizondiscovery .com www.horizondiscovery.com Tel: 01223 655580 7100 Cambridge Research Park, Waterbeach, Cambridge CB25 9TL

Horizon Discovery is a leading provider of research tools to support the development of personalized medicines. The Company’s proprietary virally-mediated precision gene engineering technology, GENESIS, enables any endogenous gene in a human cell line to be altered quickly, reliably and without introducing unwanted and confounding genotypes and/or phenotypes. Using GENESIS, Horizon Discovery has developed X-MAN (gene-X; Mutant And Normal) cell models, which are the world’s first source of genetically-defined and patient-relevant human cell lines.

The Company’s broad panel of over 350 different X-MAN cell lines, which have been referred to as “patients-in-a-testtube,” accurately model the disease-causing mutations in cancer patients. The X-MAN cell lines are being used by academic and industry leaders to identify the effect of individual mutations on drug activity, patient responsiveness and resistance, and to successfully predict which patient sub-groups will respond to currently available, and future drug treatments. This supports the design of shorter, more focused clinical trials, making it possible to identify the ‘right drugs’ for the ‘right patients’ based upon the unique genetic mutations that define their disease.

Founded by Dr Chris Torrance and Professor Alberto Bardelli, and with headquarters in Cambridge, UK, the company builds on a long heritage in precision gene engineering, cancer research and translational medicine. Horizon’s GENESIS technology has won numerous awards, and there are currently more than 400 scientific papers published relating to the use of GENESIS technology and X-MAN cell line pairs. GENESIS and X-MAN are both registered trademarks of Horizon Discovery Limited.

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Horizon Discovery Services

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info@horizondiscoveryservices. com

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www.hypoxium.com 260 Cambridge Science Park, Milton Road, Cambridge CB4 0WE

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Huntingdon Life Sciences www.huntingdon.com

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Huntingdon Life Sciences has considerable experience in supporting the development of biotechnology-derived pharmaceuticals, having been involved in the safety testing of these products since they were first introduced in the early 1980s. We have worked with a large number of companies in developing a diverse range of products including; recombinant proteins, monoclonal antibodies, vaccines, gene and somatic cell therapy, antisense products and conventional biologics. Our services include, - multiple species studies including transgenics histology / immunocytochemistry laboratory to assess cross-reactivity of monoclonal antibodies with human and animal tissues - methods to detect biopharmaceuticals and antibodies raised to them in biological matrices methods to assess the effects of biopharmaceuticals on immune status and function - in vitro and in vivo models to assess pharmacology and efficacy - range of safety pharmacology models - range of reproductive toxicity studies - range of genotoxicity studies

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Illumina Cambridge Ltd info@illumina.com www.illumina.com Chesterford Research Park, Little Chesterford, Nr Saffron Walden, Essex CB10 1XL

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At Illumina, our goal is to apply innovative technologies and revolutionary assays to the analysis of genetic variation and function, making studies possible that were not even imaginable just a few years ago. These studies will help make the realization of personalized medicine possible. With such rapid advances in technology taking place, it is mission critical to have solutions that are not only innovative, but flexible, scalable, and complete with industry-leading support and service. As a global company that places high value on collaborative interactions, rapid delivery of solutions, and prioritizing the needs of its customers, we strive to meet this challenge. Illumina’s innovative, array-based solutions for DNA, RNA, and protein analysis serve as tools for disease research, drug development, and the development of molecular tests in the clinic. leading-edge products and services Illumina has developed a comprehensive line of products that address the scale of experimentation and the breadth of functional analysis required to achieve the goals of molecular medicine. Our offering includes leading-edge solutions for: SNP genotyping Copy number variation DNA methylation studies Gene expression profiling Lowmultiplex analysis of DNA, RNA, and protein Our products and services are used by a broad range of academic, government, pharmaceutical, biotechnology, and other leading institutions around the globe.

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Immune Targeting Systems

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info@its-innovation.co.uk

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Tel: 020 7691 4908

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www.its-innovation.com

London Bioscience Innovation Centre, 2 Royal College Street, London NW1 0NH

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Immune Targeting Systems (ITS) is a London based Biotech Company developing vaccines for mutating viruses and cancer underpinned by its DepoVaccine™ & Densigen™ technology platforms. ITS’ lead program, a synthetic universal influenza vaccine (Flunisyn™) targeting all potential seasonal and pandemic flu strains, has completed phase-I clinical testing. Phase-1b / 2a clinical studies will initiate in 2012.

ITS is seeking to raise a $28m Series-B funding to expedite its universal Hepatitis-B therapeutic vaccine (targets major genotypes relevant to 7MM & China) through phase-I, lead optimise an oncology indication (potential to expedite IND) and provide a commercialisation run-way whilst a commercialisation partner is sought. ITS lead investors the Novartis Venture Fund, HealthCap and Truffle Capital will support this round. Flunisyn will be used as an add on to the seasonal flu vaccine in the elderly to ensure a full complement of immunological correlates of protection are provided at immunisation. Today’s seasonal flu vaccine is <30% effective and only generates antibodies, limiting its clinical benefit.

Phase-I data highlights an excellent safety profile and it’s best-in-class potential when assessing key immunological performance parameters; vaccine responder frequency (eliminating need for HLA selection), breadth & magnitude of response, booster amplification (no requirement for a heterologous prime-boost strategy). The induced immune responses are able to target multiple variants of H1N1, H2N2, H3N2, H5N1, H7N7 & H9N2 strains including all pandemic / zoonotic flu strains. The Densigen platform fully predicts the human immune response. Oncology: Overexpressed tumour associated antigens shared by 10 high unmet need cancers were mined for Densigens. Such Densigens frequently contain clinically validated peptides including those associated with survival benefits. Cancer vaccines will offer broad cancer indication utility whilst eliminating HLA sub-typing.

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Innova Biosciences info@innovabiosciences.com www.innovabiosciences.com Tel: 01223 496 170

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Fax: 01223 496 172 Babraham Hall, Babraham, Cambridge CB22 3AT

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Innova Biosciences Ltd’s core business is bioconjugation (antibody labeling) – the joining of two molecules to form a hybrid ‘conjugate’. Conjugates are used in hospital and research labs around the world; they also feature in consumer items such as pregnancy test kits (the conjugate is responsible for the blue line). Innova’s one-step conjugation method (Lightning-Link™) massively simplifies the production of conjugates that are needed for research and immunodiagnostic applications. Innova also offers exclusive services for optimizing the performance of conjugates and developing more sensitive immunodiagnostic tests. Innova also sells several niche products to pharmaceutical research and development labs

International Nanobiological Testbed Ltd Salvatore Santoli sf.santoli@gmail.com Tel: 020 7691 1122 Fax: 020 7681 9129 2 Royal College Street, London NW1 0NH

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The INT – International Nanobiological Testbed Ltd was registered in England and Wales in 1997 by an international group of scientists who have been among the first ones who formulated the aims and principles of Nanotechnology and Nanobiology. The industrial mission of the company, to be realized through high-tech investors joint venture capital, is to be found in its corporate name: i.e., to work as a testbed of laboratory results in nanoscale science and technology, mainly in Nanobiology, as to their fitness for mass production and for their making into practical technologies, possibly through just a small step involving further research. The R&D dept. of the company is basicly involved in interdisciplinary efforts for designing devices, systems and processes for research into Life Sciences, mainly on the nanoscale, and for developing the field of BioNanotechnology as a bioinspired approach to devising nanodevices and systems by mimicking nanoscale biological structures.

The current R&D activity of the company concerns biosensors, bioNEMS, nanoactuators, bionanophotonics, High Performance Computing and novel approaches to computer science and technology to better deal with information processing involving the complexity of living systems, and to devise systems for bioinspired Artificial Intelligence. For realizing its interdisciplinary view as a necessary approach to the emerging nanoscale technologies and to modern science, the company is open to cooperation and business. Its in-house Intellectual Property Dept. takes care of patentable material arising from the work of the R&D Dept.

www.iqur.com Tel: 020 7691 1122 Fax: 020 7681 9129 London Bioscience and Innovation Centre, 2 Royal College Street, London NW1 0NH

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iQur Ltd info@iqur.com

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iQur was founded in April 2003 as a spin-out from the University of Southampton Liver group. Focused on liver disease the company was initially established with three Divisions; Therapeutics, Diagnostics and Drug Distribution. The business model was that the other two Divisions would provide some early support for Therapeutics, the main research and development Division of the company.

As the therapeutics programme has progressed attention has been concentrated on this division. In 2007 iQur sold the Drug Distribution division to Three Rivers Pharmaceuticals. In December 2008 the Diagnostics Division was sold to Delphic Diagnostics, with iQur retaining an exclusive agreement with Siemens to market the Enhanced liver Fibrosis Test. This is a diagnostic for liver damage developed by the Founder.

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Isogenica Ltd Dr. Ambili Nair, Business Development info@isogenica.com www.isogenica.com Tel: 01799 533680 Fax: 01799 531604 The Mansion, Chesterford Research Park, Little Chesterford, Essex CB10 1XL

Isogenica specialises in providing protein engineering services to pharmaceutical and biotechnology companies.

Isogenica’s core drug discovery platform , “CIS display”, offers rapid discovery, identification and design of new peptide, polypeptide and antibody lead compounds. CIS display can quickly construct polypeptide libraries of unprecedented size and complexity in vitro, without the need for cloning. A library of up to a hundred trillion different clones can be easily generated in a few hours and quickly searched so that better products and motifs can be selected in just a few days. CIS display technology has provided hits and information against a wide range of targets and has advantages over alternative technologies. Isogenica has recently upgraded the platform by integrating high throughput screening and by automating the process thereby increasing capacity to supply its growing customer base. CIS display is adaptable for the display of different proteins and non-exclusive licences are available for scFv and other polypeptide scaffolds technology in defined fields, or available under fee-forservice use.

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Kymab Limited Paulette Alexander Paulette.Alexander@kymab.com www.kymab.com Tel: 01223 833301

Kymab is using embryonic stem cell technology to develop its KymouseT platform, which encompasses the entire diversity of the B lymphocyte component of the human immune system. This will allow the discovery of highly selective, potent and well-tolerated monoclonal antibody-based biopharmaceuticals. These new drugs will include best-in-class antibodies directed against clinically precedented drug targets and first-in-class drugs against novel targets.

Fax: 01223 839133

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Kymab Limited, Meditrina (B260), Babraham Research Campus, Cambridge CB22 3AT

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Lab21 info@lab21.com www.lab21.com Tel: 01223 395450 Fax: 01223 395451 184 Cambridge Science Park, Cambridge CB4 0GA

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Lab21 is a rapidly growing global provider of state-of-the-art diagnostic products and services, supporting blood bank screening, medical diagnostics and drug discovery. Its customers include international healthcare providers, pharmaceutical and biotechnology companies. The product division of the Company manufactures immunodiagnostic kits and reagents that are distributed into 110 countries globally through both direct and indirect channels. A key focus is infectious diseases for the blood banking market, with assays available for syphilis, CMV and malaria. The service division has a growing test portfolio providing companion diagnostics and high technology molecular assays for the growing integration of personalised medicine into healthcare. These services are currently in infectious diseases, oncology, virology and pharmacogenetics areas with emerging interests in cardiovascular and metabolic disease. Lab21 has 5 sites in the UK with two highly accredited reference laboratories and 3 immunodiagnostic manufacturing sites. The Company also has two sites in the State of South Carolina for its US operations.

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Lonza Biologics Plc Philippe Stas, Head Applied Protein Services appliedproteinservices@lonza.com www.lonzagroup.com

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Tel: 01223 895102 / 01223 895100 Lonza Biologics plc, Granta Park, Great Abington, Cambridge CB21 6GS

Lonza is one of the world’s leading suppliers to the pharmaceutical, healthcare and life science industries. Its products and services span its customers’ needs from research to final product manufacture. Lonza is the global leader in the production and support of active pharmaceutical ingredients both chemically as well as biotechnologically. Lonza’s Applied Protein Services division (APS) brings quality-by-design methodologies to the development of biopharmaceuticals to produce better and safer molecules. Our team integrates unique immunogenicity and stability risk assessment and re-engineering capabilities for the development of better and safer biotherapeutics. Our technologies have been extensively validated in different molecules with remarkable results. Lonza-APS offers comprehensive services on: – In silico and in vitro T-cell Epitope & Immunogenicity assessment – In silico Protein Aggregation & Stability assessment and avoidance – In silico Protein Engineering & Stabilization – Antibody Humanisation – In vitro Protein Design Validation (productivity, activity and stability) – Rapid supply of sub-gram quantities of recombinant proteins

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Medivir AB

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Paul Wallace PhD, Executive Vice President, Head of Business Development

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paul.wallace@medivir.com

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Tel: 01799 532100

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www.medivir.com

The Mansion, Chesterford Research Park, Little Chesterford, Essex CB10 1XL

Medivir was founded in 1988 as a spinout from AstraZeneca’s antiviral research unit.Today’s operations focus on the development of pharmaceuticals against infectious diseases, mainly those caused by viruses. The company was listed in 1996 and is traded on the Nasdaq OMX, on the Stockholm Stock Exchange Mid-cap list.

In November 2011 the company had a market capitalization of $400M. Medivir’s first self-developed product, the cold sore treatment Xerclear®/Xerese™, is in launch phase with partners GlaxoSmithKline and Meda AB. The R&D portfolio includes 10 projects, 7 of which are run by partners. Three of these address hepatitis C and include TMC435, an HCV protease inhibitor, now in phase 3 trials with partner Johnson & Johnson/Tibotec. Medivir recently acquired Biophausia AB to establish a presence as a pharmaceutical sales organisation, and in part preparation for the anticipated launch of TMC435 in its home territory. At year-end 2010 Medivir’s cash position was approximately $100M.

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Melbourn Scientific Ltd Martin Westcott martin.westcott@ melbournscientific.com www.melbournscientific.com Tel: 01763 261648 Saxon Way, Melbourn, Cambs SG8 6DN

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Melbourn Scientific are a Cambridge based provider of world leading contract analytical, formulation and product development services for the pharmaceutical, biopharmaceutical, biotechnology and healthcare industries. From lead optimisation to finished product testing our experienced team offer a extensive support including formulation/ reformulation projects and product development on a wide range of pharmaceuticals, biopharmaceuticals, drug delivery devices and medical devices.

MISSION Therapeutics Ltd enquiries@missiontherapeutics .com www.missiontherapeutics.com Tel: 01223 497454 Babraham Research Campus, Meditrina, Cambridge CB22 3AT

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MISSION Therapeutics was founded in 2011 by a team of scientists including Professor Steve Jackson, Dr Niall Martin, Dr Xavier Jacq and Dr Keith Menear, along with Cancer Research Technology and Cambridge University.

Its activities are based on the research of Professor Steve Jackson, Professor of Biology at the University of Cambridge and Head of Cancer Research UK Laboratories at The Gurdon Institute in Cambridge. The company has received £6 million in Series A funding from a strong venture capital syndicate comprising lead investors Sofinnova Partners, Imperial Innovations, SR One and Roche Venture Fund. MISSION Therapeutics is developing a broad platform of technologies for the discovery and further development of first-in-class modulators of enzymes involved in cancer and other diseases. The company will predominantly exploit the new and exciting research emerging on ubiquitin pathways that control cellular responses to DNA damage. MISSION Therapeutics’ scientists will develop drugs to inhibit the proliferation of tumour cells, building on their experience in exploiting the concept of synthetic lethality, now an established and powerful mechanism to selectively kill tumour cells.The company is based at the Babraham Research Campus, around 7 miles south of Cambridge.

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Neusentis

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www.pfizer.com The Portway, Granta Park, Cambridge CB21 6GS

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Novacta Biosystems Limited Jane Whitrow PhD FCA VP Corporate Affairs jane.whitrow@novactabio.com www.novactabio.com Tel: 01707 356130

Novacta is an R&D focused company developing new anti-infectives and providing services to the fine chemical & industrial biotech sectors. Our therapeutics division is focused exclusively on the discovery and development of novel antibacterial agents to treat new and emerging infectious diseases, particularly those caused by antibiotic resistant ‘super-bugs’. Our lead product for the treatment of C.difficile is currently undergoing preclinical safety assessment. Our services division works with customers in the pharma, agrichem, industrial biotech, flavours & fragrances and cosmetics sectors. Our expertise includes: 1) Microbial metabolic engineering: 2) Biocatalysis: 3) API/agrochemical metabolites:

12 Cambridge Science Park, Milton Road, Cambridge CB4 0FZ

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Novus Biologicals Ltd www.novusbio.com

The mission of Novus Biologicals, Ltd. is to accelerate scientific discovery by developing and marketing unique products in the forefront of science. Novus Biologicals was organized to provide the biological research community with a mechanism for commercializing unique biological materials. We also focus on continually monitoring scientific trends and supplying materials to serve these trends. Novus Biologicals Ltd. core focus is the serve the research community of the United Kingdom and the European Union.

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Origin Sciences Limited Hugo Lywood

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info@originsciences.com www.originsciences.com Tel: 01223 750490 1 Riverside, Granta Park, Great Abington, Cambridge CB21 6AD

Origin Sciences Limited is a UK based organisation. The company is dedicated to researching, developing and commercialising new products for the early and accurate detection of bowel disorders, in particular colorectal cancer. Many thousands of hours of research by our own research and development team, combined with our clinical collaborators have enabled the launch of our first commercial IVD based product, eDNA Pre-View. eDNA Pre-View is an innovative, minimally invasive and inexpensive test that can be used as a colonoscopy qualification tool for symptomatic patients. This product is the first of a series of tests to be released. All of these products utilise the Origin Cell Sampling device. This is an operator and patient friendly device that has been carefully designed and perfected with the assistance of many clinicians. The final product can be operated by a nurse and the virtually painless cell collection procedure takes less than five minutes to perform. As a company Origin is interested in talking to global distributors, potential partners and customers with a view to driving this unique product forward.

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Pathology Diagnostics Ltd Dr Madhuri Warren

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info@pathologydiagnostics.com

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Tel: 01223 421334

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www.pathologydiagnostics.com

St John’s Innovation Centre, Cowley Road, Cambridge CB4 0WS

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Pathology Diagnostics Ltd is an independent GCLP accredited histopathology CRO delivering high quality tissue diagnostics services to industry Research & Development scientists engaged in drug and biomarker development We specialize in the provision of high end clinical diagnostics and quantitative image analysis on human tissues on studies from early discovery / preclinical to Phase I-III clinical trials particularly in the field of oncology. Our core strengths are our breadth of experience from molecular biology to human diagnostic pathology and our ability to interact with both scientists and clinicians to support the development of scientific discoveries into new therapeutics and biomarkers for the clinic. We pride ourselves in offering a tailored and flexible service covering project management, IHC assay validation, IHC testing and diagnostic analysis, delivered by experienced staff with several decades of combined experience in the field. We pride ourselves in understanding your project needs by providing advice and high quality consistent reliable results on time enabling you to make informed data-driven decisions on the likely success of your product programmes.

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Pharmorphix

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info@pharmorphix.com

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Tel: 01223 425 105

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www.safcglobal.com

250 Cambridge Science Park, Milton Road, Cambridge, Cambridgeshire CB4 0WE

SAFC Pharmorphix® is a world leading provider of pre-formulation services to the pharmaceutical and biotechnology sectors. Our experience coupled with our state of the art facilities, places Pharmorphix® at the forefront of pharmaceutical research and development. Our focus is to drive molecules in the clinic by understanding and modifying the physical properties of the drug substance to ensure patient benefit, rapid development and protection of intellectual property. Pharmorphix’s® R&D support services include polymorph investigation, salt selection, physicochemical property determinations, co-crystallisation, chiral separation and crystallisation studies.

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Plasticell ltd Dennis Saw (CEO) dennis@plasticell.co.uk www.plasticell.co.uk Tel: 07811 168 177 Fax: 0207 193 2605

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London Biosciences Innovation Centre, 2 Royal College Street, London NW1 0NH

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Plasticell is a path-finding stem cell biotechnology company that has developed state-of-the-art, high throughput methods to discover optimized stem cell differentiation protocols. Plasticell’s award winning CombiCult(TM) platform allows cell-culture variables to be tested in millions of combinations simultaneously. It has been used to discover optimal protocols for the differentiation of embryonic, adult or induced pluripotent stem cells in record time, and at the fraction of the cost of traditional trial-and-error experimentation. The CombiCult(TM) workflow includes a proprietary bioinformatics suite that unravels the cell culture history of each cell through the massively multiplexed experiments. It also detects patterns in the cell culture histories, such as recurring conditions at each cell culture step, and common cell culture pathways. Although invented to discover optimal differentiation protocols, the flexibility of the platform also allows for a multitude of other applications such as: production of high-quality cell-types for therapy or toxicity screening; discovery of higher-yielding or higher-quality cells for bioprocess; production of optimal maintenance or differentiating media while eliminating serum and/or animalderived components; discovery of small-molecules that direct stem cell differentiation for regenerative drug discovery, and more. Plasticell was founded 2002 and advised by a pre-eminent scientific team including two Nobel laureates.

Polytherics Sally Waterman, CEO sally.waterman@polytherics.com www.polytherics.co.uk Tel: 020 7691 4927 The London BioScience Innovation Centre, 2 Royal College Street, London NW1 0NH

A PolyTherics is a biotechnology company that has developed proprietary linker technologies which allow conjugation at specific sites on proteins or peptides. PolyTherics has three proprietary precision conjugation technologies: • TheraPEG™ - conjugation across one or more disulfide bonds naturally present in a protein or peptide • HiPEG™ - conjugation at a histidine tag that is expressed at one or both ends of a protein or peptide • CyPEG™ - conjugation at the thiol group of free cysteine within a protein or peptide The company is applying these conjugation technologies for: • Half-life extension (PK/PD optimisation) • Antibody Drug Conjugates and other protein based drug conjugates • Imaging • Reduction of aggregation of therapeutic proteins • Development of new protein formats e.g. bispecifics based on antibody fragments PolyTherics offers product specific licences for application of its technologies to pharma and biotech companies to enable development of better biopharmaceuticals. The company welcomes the opportunity to conduct feasibility studies with its technologies and will consider collaborative partnering approaches.

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Population Genetics Technologies Ltd Dr Frank Massam frank.massam@popgentech.com www.popgentech.com Tel: 01223 497350 Babraham Research Campus, Cambridge CB22 3AT

Population Genetics Technologies Ltd (PopGenTech) has developed GenePooling© technology to characterise genetic variation in large populations, rapidly and cost-effectively. GenePooling© identifies novel genetic variants in candidate genomic regions that: (i) predispose individuals to disease, (ii) are useful for biomarker development for strati?ed clinical trials and personalised medicine and (iii) enable classification of pathogens for infectious disease. We tag individual genomes with unique DNA sequences, pool all genomes as a single mixture, and then extract and analyse candidate sequences in this population pool. Analysis together with clinical data allows direct hypothesis testing of candidate genes. From January 2011, PopGenTech will be offering GenePooling© as a service to pharmaceutical companies, CROs, and researchers studying the implications of genetic variation.

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ProMetic Biosciences Ltd

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www.prometicbiosciences.com Tel: 01223 420300 Fax: 01223 420270 211 Cambridge Science Park, Milton Road, Cambridge CB4 0WA

ProMetic Biosciences Ltd (PBL) is a wholly-owned subsidiary of Canadian-based ProMetic Life Sciences Inc., and since 1987 has pioneered the design, development and manufacture of affinity separation products and technologies. PBL specialises in synthetic affinity ligands - Mimetic Ligands™ - which are used by numerous companies making PBL a key supplier to the global life sciences industry. The chemical diversity of PBL’s synthetic ligand libraries allows application to almost any target protein. PBL’s bioseparation products are developed and manufactured in-house and the company is ISO 9001 accredited. PBL’s affinity technology may be applied to the capture of targeted proteins directly from biological source material, the separation of target protein from other components, or the capture of specific contaminants.

Applications include the purification of: antibodies, antibody fragments, albumin, albumin-fusion proteins, plasma proteins, glycoproteins, proteases and other recombinant proteins. PBL has also applied it’s technology to the capture and removal of prion proteins (vCJD) from blood, plasma and plasma-derived products. In partnership with the American Red Cross, PBL has developed the Prioclear™ range of prion binding adsorbents, applications of which include the revolutionary P-Capt® filter, a CE mark approved prion reduction device (developed in collaboration with MacoPharma SA) which provides a means of significantly reducing the risk of vCJD transmission by blood transfusion. Additionally, Prioclear™ adsorbents have been applied to plasma and plasma-derived products to improve prion safety margins and reduce the risk of vCJD transmission.

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Proxima Concepts Ltd Tel: 0207 419 5980 www.proximaconcepts.com The London Bioscience Innovation Centre, 2 Royal College Street, London NW1 0TU

Proxima Concepts Limited is an international bio-pharmaceutical R&D company employing proprietary drug delivery and discovery technologies to help the biotechnology industry achieve its potential in the field of healthcare and medical therapeutics. The company is based in Jersey, United Kingdom and operates internationally, its participants having over thirty years experience in the field of biotechnology. They have developed a strong network of collaborators internationally.

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Proximagen Limited Tim Sparey tim.sparey@proximagen.com www.proximagen.com Tel: 020 7400 7700 91-93 Farringdon Road, London EC1M 3LN

Proximagen Group is UK biotechnology company primarily focused on the development and commercialisation of novel therapeutics for diseases of the central nervous system. Proximagen is well capitalised following a £50m fund raising in June 2009 and has a broad pipeline of proprietary drug candidate programmes under development. Proximagen’s licensing interests include novel small molecules, targets with a pre-clinical or clinical proof of concept and technologies with strong patent protection in Parkinson’s disease, Alzheimer’s disease / cognition, epilepsy and neuropathic pain. Programmes in late lead optimisation through to Phase II will be considered. Proximagen also has an active out-licensing strategy including a number of clinical and pre-clinical stage assets. In addition the company has in place a number of partnerships including with Upsher-Smith Laboratories, Lundbeck, Altacor, the NIH and BrainCells Inc.

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Quotient Bioresearch Ltd info@quotientbioresearch.com www.quotientbioresearch.com Newmarket Road, Fordham, Cambridge CB7 5WW

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Quotient Bioresearch is a leading provider of early stage and specialist drug development services to life science clients worldwide. We provide tailored solutions for pharmaceutical, biotechnology and agrochemical clients, using state-of-the-art technologies underpinned by unparalleled medical, chemical and biological expertise. Our consultative, science-driven approach ensures the highest quality service to support and accelerate new product development. Our extensive range of capabilities spans Chemistry and Metabolism, Bioanalytical Sciences, and Clinical. These can be provided independently or integrated into bespoke work programmes. For additional information or to discuss your specific needs, contact us on info@quotientbioresearch.com or visit www. quotientbioresearch.com

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Rapid Biosensor Systems Ltd

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Dennis Camilleri

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dennis.camilleri@rapidbiosensor .com www.rapidbiosensor.com Tel: 01480 390648 Babraham Hall, Babraham, Cambridge CB22 3AT

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Rapid Biosensor Systems (RBS) is a technology and business development company based at the Babraham Research Campus in Cambridge. RBS patented technologies are developed into medical devices for the detection of infectious diseases. The company’s first product is a low-cost, portable, disposable Breathalyser for rapid screening of active TB in Humans. The TB Breathalyser enables results in a few minutes at the PointOf-Care and it is the fastest test for screening while people wait for their test results. Prototyping is done with manufacturing in mind. RBS has a strategic partnership with Ortho Clinical Diagnostics, Inc. – a Johnson & Johnson Company, to assist RBS with production design optimisation for the Breathalyser and manufacturing ramp-up. RBS business is based on building strong IP and product design solutions which are licensed to global healthcare organisations. The company seeks collaborative partnerships and potential licensees for other medical devices based on its immunosensor platform. RBS business is based on building strong IP and product design solutions which are licensed to global healthcare organisations. The company seeks collaborative partnerships and potential licensees for other medical devices based on its immunosensor platform.

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Recombinant Antibody Technology Ltd info@ratltd.net Maia Building 270, Babraham Research Campus, Cambridge CB22 3AT

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Recombinant Antibody Technology Ltd. is specializing in the generation of large recombinant DNA constructs using YAC and BAC technologies. Currently, the company is working with Open Monoclonal Technology, Inc., a US based biotechnology company, on the generation of recombinant immunoglobulin loci for the generation of genetically engineered rats expressing antibodies with fully human idiotypes.

Rethink Orthopedics Ltd Phillip Waterman info@rethinkorthopedics.com www.rethinkorthopedics.com

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Incorporated in the UK in July 2011, Rethink Orthopedics designs, develops, contract manufactures and commercialises devices, instruments and technologies containing patented innovations in the field of orthopedic surgery. Initial products, in varying stages of development, include new methods for treating severe spinal deformities, osseous avascular necrosis and complex pelvic fractures.

Tel: 0751 385 9860 2 Royal College Street, London NW1 0NH

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Royal Veterinary College Patricia Latter platter@rvc.ac.uk www.rvc.ac.uk Tel: 0203 214 8119 Royal Veterinary College, Royal College Street, London NW1 OTU

The Royal Veterinary College (RVC) is the UK’s first and largest veterinary school and a constituent College of the University of London. Our research programmes address both basic and clinical problems in the biosciences, with applications in veterinary and human medicine. We can offer a single point of access, from basic research, to preclinical contract studies and veterinary clinical trials with expertise to advise on GCP trial protocols.

Our ‘Lifestyle’ research programme focuses on areas where chronic degenerative diseases influence quality of life in the aging population: musculoskeletal health; cardiovascular and renal health and nutrition; obesity and insulin resistance and structure and motion: • Musculoskeletal diseases (e.g. Arthritis) • Cardiovascular and Renal Disease (e.g. Hypertension) • Nutrition (e.g. Diabetes) Our Infection and Immunity programme addresses viral, bacterial and parasitic pathogens.

We have particular research expertise in: • Emerging zoonotic diseases (avian influenza, Rift Valley fever) • MRSA (methicillin-resistant Staphylococcus aureus) and antimicrobial resistance detection • Common livestock infections, e.g. porcine post-weaning multi systemic wasting syndrome (PMWS), Bovine viral diarrhoea virus vaccine • Domestic animal infections, e.g. canine infectious respiratory disease • Innate immunity in domestic species and the interaction of the innate immune system with a range of pathogens. In addition, we support the veterinary and related professions through three referral hospitals, diagnostic services and continuing professional development courses. RVC owns and operates the London BioScience Innovation Centre, based at its Camden campus in central London.

deborah@sciad.com www.sciad.com London Bioscience Innovation Centre, 2 Royal College Street, London NW1 0NH

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Sciad Ltd Deborah Cockerill

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Sciad is a digital marketing agency that works with businesses in healthcare, life science, the environment and other science and technology-based sectors. We use integrated digital communications to drive up reputations and increase website traffic, connecting with the audiences that matter most by maximising the power of the web including: • Search Engine Optimisation • Pay per click • Online PR and Social Media • Website Design and Development • Branding and design The Sciad team are experts in digital communications and have extensive experience of working in science and technology communications.

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Selcia Limited Simon Bury (Discovery), Dave Roberts (Radiolabelling) contact@selcia.com www.selcia.com Tel: 01277 367000 Fyfield Business and Research Park, Fyfield Road, Ongar, Essex CM5 0GS

Selcia is a leading contract research laboratory providing both 14C radiolabelling and integrated drug discovery services.

Operating from modern facilities in Ongar, Essex (UK) and Hopkinton Massachusetts (USA) Selcia has a GLP certified analytical laboratory and a Good Manufacturing Practice (GMP) certificate for the preparation and 14C labelling of Active Pharmaceutical Ingredients (APIs). Selcia Discovery provides integrated drug discovery services to pharmaceutical and biotechnology industries; these services include in vitro biology, fragment screening, medicinal chemistry, and in vitro ADME/PK evaluation. Selcia’s scientists act as integrated project teams within the customer group striving to produce robust drug candidates against its partners’ biological targets. Selcia’s expertise in capillary electrophoresis (CE) offers clients the benefits of a versatile and proven technology applied to drug discovery screening on a wide variety of targets including protein-protein interactions. Selcia’s proprietary fragment screening service, CEfrag™ is a powerful application of this technique at the outset of a drug discovery programme. Selcia’s radiolabelling division produces 14C radiolabelled compounds for a global customer base encompassing both the life sciences and chemical industries. Applications of the radiolabelled products prepared by Selcia include: preclinical and clinical drug metabolism studies; mass balance, microdosing, research and regulatory studies of cosmetic products; and environmental fate studies of agricultural and industrial chemicals.

www.onenucleus.com

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Selective Antibodies Limited Declan Cunningham declan@selectiveantibodies.com www.selectiveantibodies.com Tel: 01732 468670 / 07887 633888

Selective Antibodies Ltd is a UK based diagnostics company with the prime focus of overcoming key technological problems central to the production of high performance point of need systems for small target molecules such as: medicaments, natural and unnatural toxins (such as fungal toxins and pesticides), drugs of abuse, CBRNE substances, and other substances of importance to forensic investigation, the environmental and food and water industries.

145 High Street, Sevenoaks, Kent TN13 1XJ

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Senexis Limited info@senexis.com www.senexis.com Tel: 01223 496160 Babraham Research Campus, Cambridge, CB22 3AT

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Shire PLC

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Unity Place, Hampshire International Business Park, Chineham, Basingstoke, Hampshire RG24 8EP

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Senexis is a small-molecule drug development company that is committed to revolutionising the treatment of diseases resulting from the inevitable process of ageing. Senexis is advancing a pipeline of novel treatments for conditions arising from the toxicity of amyloid-like proteins. Our pipeline is currently focused on discovering potent and selective therapies for the treatment of Alzheimer’s disease. Optimised compounds for treating Alzheimer’s disease have demonstrated pre-clinical efficacy in a variety of established models of memory and learning and have completed development candidate selection studies. Senexis is actively seeking to enter into collaborations and licensing deals with established pharmaceutical companies. Senexis plans to offer a balanced portfolio of pre-clinical or early clinical licensing opportunities to the pharmaceutical sector. SEN1500 has been shown to be an effective inhibitor of amyloid toxicity and amyloid aggregation. The phamacokinetic profile and brain penetration properties of SEN1500 are also promising.

Direct binding of SEN1500 to relevant amyloid species has been demonstrated and, in an acute behavioural model, oral SEN1500 provides a dose-dependent protection of the cognitive deficit, induced by brain-injected amyloid. Chronic oral administration of SEN1500 also provides protection in Alzheimer’s disease models and the biochemical and histological data are consistent with SEN1500 promoting amyloid clearance from the brain. So far, no orally bioavailable and brainpenetrant compounds that bind directly to amyloid have been adequately tested in the clinic. SEN1500, with its exciting pharmacological profile provides for the opportunity to establish whether this potentially disease-modifying approach could provide a successful treatment for Alzheimer’s disease.

As one of the world’s leading specialty biopharmaceutical companies, Shire has emerged as a company fully focussed on a single purpose: to enable people with life-altering conditions to lead better lives. Shire HGT, a vastly experienced and highly dedicated business unit of Shire Pharmaceuticals Ltd, specialises in discovering and developing innovative treatments for rare genetic diseases such as Fabry disease, Hunter Syndrome, Gaucher disease, hereditary angioedema and metachromatic leukodystrophy. Products such as ELAPRASE for Hunter Syndrome, REPLAGAL for Fabry disease and FIRAZYR for hereditary angioedema are available in markets around the globe, with FDA and EMEA regulatory approvals for velaglucerase alfa for Gaucher disease expected in 2010. Shire HGT employs nearly 1000 people worldwide who work across range of research and development, production and commercial disciplines. Shire HGT has offices in Basingstoke, UK and Cambridge/Lexington, US and a network of offices and distribution channels throughout Europe, Middle East, Africa, South America, Canada and the Pacific Rim.

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Smart Holograms Ltd info@smartholograms.com www.smartholograms.com Tel: 01223 393 400 200 Cambridge Science Park Milton Road, Cambridge CB4 0GZ

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Sphere Medical Ltd enquiries@spheremedical.com www.spheremedical.com Tel: 01223 875222 Harston Mill, Harston, Cambridge, Cambridgeshire CB22 7GG

A Sphere is a medical device business completing the development of a range of monitoring and diagnostic products designed to provide significant improvements in patient management in a number of hospital specialities. Sphere’s products are expected to allow near real time measurement of blood gases, various electrolytes and drug levels with laboratory accuracy, at the patient’s bedside. This information can be used in a wide range of medical applications and is intended to enable faster clinical decision making and consequently to improve the management of patients.

Sphere’s lead products based on its proprietary microanalyser platform technology are a disposable patient-attached arterial blood analyser for use in the ICU and OR (‘Proxima’) and a device for continuous blood monitoring in the bypass circuit in patients undergoing cardiopulmonary bypass surgery (‘CPB device’). In addition, Sphere markets a propofol drug measurement device (‘Pelorus 1000’) . In each case, these products target patients requiring close monitoring and frequent levels of blood testing. The primary market for Sphere’s products is that of POC technology and devices for the ICU and OR. Sphere has also examined the potential application of the microanalyser technology in neonatal intensive care as well as carrying out a successful feasibility study with a world-leading company in the renal therapeutic area.

There are many further applications of Sphere’s microanalyser platform technology, which may be explored to enable the future expansion of Sphere’s product roadmap and revenue opportunities in the future. Sphere is listed on the AIM market of the London Stock Exchange.

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Stabilitech Ltd

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www.stabilitech.com

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Paul Bello

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jo.kellet@stemcellsciences.com www.stemcellsinc.com Tel: 01223 499 160 Minerva Building 250, Babraham Research Campus, Cambridge CB22 3AT

Stem Cell Sciences (SCS), a wholly owned subsidiary of StemCells, Inc., is engaged in the development and commercialization of cell-based enabling technologies for research, drug discovery and drug development. A leader in the field since 1994, SCS has developed innovative, proprietary technologies to generate and propagate highly purified stem cells and their differentiated progeny. SCS combines a portfolio that includes embryonic, neural and other tissue-specific stem cells with automated platforms and proprietary reagents for the production and testing of such cells and their progeny for drug discovery and toxicological screening applications. With a proven track record of collaboration with leading academic centres of excellence and international biotechnology and pharmaceutical companies, SCS is an ideal partner for cell?based assay development and screening applications. SCS is also developing and marketing specialty cell culture media products under the brand SC Proven®.

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Synthace Limited info@synthace.com www.synthace.com London Bioscience Innovation Centre, 2 Royal College Street, London NW1 0NH

Synthace is the first applied synthetic biology startup in Europe, and is focused on using a proprietary platform technology to rapidly engineer microorganisms for the biosynthesis of high value biologics and fine chemicals.

Incubated at UCL and The London Bioscience Innovation Centre, Synthace benefits from access to millions of pounds of equipment, and over 120 years of industrial, entrepreneurial, and academic experience of its founders and advisors.

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Takeda Cambridge Limited Linda Millett info@takedacam.com www.takedacam.com Tel: 01223 477910

Takeda Cambridge (TCB) is a drug discovery company specialising in identifying and validating innovative drug targets. TCB has established world-class target identification and validation capabilities. We have developed a promising pipeline of novel drug discovery targets and compounds in such key areas of unmet medical need as CNS disorders and metabolic-related diseases. Worldwide, Takeda develops, manufactures and markets a broad range of pharmaceutical products and strives towards better health for patients worldwide through leading innovation in medicine.

418 Cambridge Science Park, Cambridge CB4 0PA

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TiGenix info@tigenix.com www.tigenix.com Cambridge Business Park, Cowley Road, Cambridge CB4 0WZ

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Total Scientific

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Dr David Mosedale

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www.totalscientific.com

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Babraham Research Campus, Cambridge CB22 3AT

info@totalscientific.com

Tel: 01223 835968

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TwistDx Ltd info@twistdx.co.uk www.twistdx.co.uk Tel: 01223 496700

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We provide a range of biomarker services to clients, to assist with many aspects of the drug discovery process and development of novel diagnostic tests. These services include: • Biomarker discovery • Clinical studies • Assay development • Bioanalysis • Data management and biostatistics

UKTI Investment Services enquiries@ukti-invest.com www.ukti.gov.uk/invest Tel: 0207 3335442 / 0845 5390419

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UK Trade & Investment (UKTI) is the Government organisation that helps UK-based companies succeed in an increasingly global economy. UKTI services are tailored to the needs of individual businesses to maximise their international success. We provide companies with knowledge, advice and practical support. UKTI also helps overseas companies bring high quality investment to the UK’s vibrant economy - acknowledged as Europe’s best place from which to succeed in global business. We provide support and advice to investors at all stages of their business decision-making. UKTI offers expertise and contacts through a network of international specialists throughout the UK, and in British Embassies and other diplomatic offices around the world. We work closely with colleagues in the Department for Business, and the Department for Health. UKTI deploys industry specialists to support the marketing of the UK Life Sciences and to identify commercial opportunities in overseas markets.

Specialists are also tasked with increasing the level of international Life Science R&D investment in the UK, promoting the benefits of R&D in the UK to a targeted group of overseas owned companies. For further details see: www.uktradeinvest.gov.uk www.uklifescience.co.uk

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UroSens Ltd

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info@urosens.com www.urosens.com

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Tel: 01223 836 556 Babraham Research Campus, Babraham, Cambridge CB22 3AT

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Vernalis Clive Evans admin@vernalis.com www.vernalis.com Tel: 01223 895555 Granta Park, Abington, Cambridge CB21 6GB

Vernalis is revenue generating development stage pharmaceutical company with significant expertise in drug development. The Group has one marketed product, frovatriptan for the acute treatment of migraine, and eight candidates in development, seven of which are designated priority programmes. Four of these priority development programmes are currently unpartnered and three are partnered. Pipeline programmes are derived from both our own research activities where we have significant expertise in fragment and structure based drug discovery, as well as from collaborations. Our technologies, capabilities and products are endorsed by collaborations with Endo, GSK, Lundbeck, Menarini, Novartis and Servier.

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Xention Limited Tim Brears tim.brears@xention.com www.xention.com Tel: 01223 493900 Iconix Park, London Road, Pampisford, Cambridge CB22 3EG

U Xention is a biopharmaceutical company specialising in the discovery and development of ion channelmodulating drugs for the treatment of atrial fibrillation. The company’s proprietary discovery approach allows the company to design and optimise potent and selective small-molecule drugs that modulate ion channel targets. The Company is developing a portfolio of products that will address current limitations in the treatment of atrial fibrillation. It is currently focussing on the development of modulators of two novel, but well characterised, potassium channels expressed in the atria and expects to develop breakthrough products in this area of huge unmet medical need.

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Zoragen Biotechnologies Dr. Igor Kojic igor.kojic@zoragenbiotech.com

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www.zoragenbiotech.com

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One Riverside, Granta Park, Great Abington, Cambridge, Cambrigeshire CB21 6AD

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Tel: 07827 237 727

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Zoragen Biotechnologies LLP Inc. is a diagnostic research company dedicated to the discovery, development and commercialization of novel techniques to make prenatal testing safer. Zoragen is a dynamic company that undertakes proof-of-concept research work, specialising in the creation of innovative IP in the area of nonInvasive prenatal diagnostics (NIPD) for global commercialisation. Recently, Zoragen had ethical approval for clinical diagnostic trials with Oxford University providing samples and clinical support granted provisionally in 2008. Shortly after, Zoragen commenced clinical diagnostic R&D with receipt of first samples in mid-2008. Todate, an IPR-protected proof-of-concept is still being developed.

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001 Ltd Amanda Knaggs Amanda.Knaggs@001ltd.co.uk www.001ltd.co.uk Tel: 0845 3892001 07870 337021 4 Cedar Court, Parkway, Porters Wood, St Albans AL3 6PA

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42 Technology Ltd

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www.42technology.com

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Meadow Lane, St Ives PE27 4LG

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Tel: 01480 302712

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As independent energy consultants we specialise in providing totally objective advice in the area of utility procurement and contract management. Our business model and driving ethic is that we WORK FOR YOU and not the energy supply companies. Our client offering is 100% risk free as our fees are generated from savings and we focus on achieving the lowest price possible for our clients. We also undertake in-depth analysis of historic electricity, gas and telecom charges and can achieve rebates going back over six years. We manage many energy portfolios for businesses across a wide range of sectors and geographical regions, including some of the UK’s best known companies.

42 Technology designs and develops innovative products and processes for medical device, biotech and drug delivery applications. We have a strong team of industry experienced engineers, complemented by a network of associates which allows us to provide teams matched to individual projects and client needs. The services we offer range from technology road mapping and concept generation through to design for manufacture and process optimisation. We have extensive experience of product and instrumentation design for medical device, pharmaceutical and biotech companies. We also provide quality and regulatory support for:- Regulatory road mapping and planning- FDA submissions and CE marking- ISO 13485 and cGMP quality system implementation, training and audit- Risk analysis and management – planning and implementation- Process and computer system validation to FDA standards- Supplier mentoring and quality improvement programs

Abcodia Ltd Dr Julie Barnes, CEO julie.barnes@abcodia.com www.abcodia.com The Network Building, 97 Tottenham Court Road, London W1T 4TP

Abcodia is a specialist company engaged in the validation and discovery of protein and DNA biomarkers linked to age related diseases. The company’s prospective biobank has over 5,000,000 serum samples derived from more than 200,000 initially healthy volunteers, 50,000 of whom have provided samples annually, making this an ideal resource for identifying biomarkers for disease screening. Commercial organisations and academic groups that are engaged in the validation and discovery of biomarkers for the screening, diagnosis and prognosis of disease, can obtain results significantly quicker by partnering with Abcodia.

Abgent Europe Ltd James Mosedale jmosedale@abgent.com www.abgent.com www.wuxipharmatech.com Tel: 01235 854042 Fax: 01235 854043 99 Milton Park, Abingdon OX14 4RY

Abingworth LLP John Shields www.abingworth.com Tel: 020 7534 1500 Fax: 020 7287 0480 Prince’s House, 38 Jermyn Street, London SW1Y 6DN

One Nucleus Directory 2012

Abgent’s tagline is The Primary Antibody Company. Abgent is one of the world’s biggest antibody manufacturers and has developed over 7,000 research antibodies in the last two years alone. We aim to create high quality antibodies against emerging targets before any other commercial company and all our products are backed up with the highest technical support. Our strengths in the antibody field lead to our acquisition by WuXi Pharmatech in October 2011. Abgent’s services include rabbit monoclonal antibody development, long & difficult peptide synthesis and bacterial, baculoviral and mammalian protein expression.

ABS Laboratories Ltd Dr Mira V. Doig mira.abs@biopark.org.uk www.abslabs.com Tel: 01707 358669 Fax: 01707 358667 BioPark, Broadwater Road, Welwyn Garden City, AL7 3AX

A ABS Laboratories is a MHRA GLP and GCP accredited CRO who specialise quantifying drugs, metabolites and biomarkers in biological fluids. We are expert at developing, validating and applying sophisticated techniques to quantify drugs and metabolites in biological fluids using LC-MS/MS, GC and GC-MS. We also quantify a vast range of biomarkers using multiplexed assays on the MSD platform. Our skills, experience and state of the art equipment means that we can support a variety of companies: Small, medium and large Pharmaceutical R&D programmes with their pharmacokinetic and biomarker assays; the NHS for specialist assay requirements supporting clinical diagnosis, screening and therapeutic drug monitoring and University and charitable organisations research programmes.

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ACM Global Central Laboratory

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Theresa Thakray

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tthackray@acmgloballab.co.uk www.acmgloballab.com

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Aviator Court, Clifton Moorgate, York YO30 4UZ

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Activiomics Ltd

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www.activiomics.com Tel: 0207 882 8283

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24 Cornhill, London EC3V 3ND

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Agenda Resource Management Ltd Tim McGuire info@agenda-rm.co.uk www.agenda-group.co.uk Tel: 0845 6445545 PO BOX 24, Hull HU12 8YJ

Agenda Resource Management was established in 1996 to provide professional services to the private and public sectors. We have developed a global network employing over 100 staff and providing clients with services around the world. Working with Government Institutions, Global Corporations and small to medium sized businesses, we have solutions for every type and size of Organisation. There are three divisions to the company, offering a range of services which have been specifically designed to be flexible and customisable to meet the specific needs of our clients: Resource Management (contract placements, recruitment and selection, facilities management, training and consultancy, careers advice and scientific recruitment). www.agenda-rm.co.uk Service Services (pre-employment screening, internet mining, CRB checks, profiling, security audits, background checks and vetting) www.agenda-security.co.uk Marketing and Communications (publishing, graphic design and artwork, campaign management, product launches, corporate identity and creative design and copywriting for marketing literature) www.agenda-mc.co.uk For a fast and professional response please contact our team today, who are waiting to take your call: 08456 44 55 45

Air Liquide UK Ltd www.airliquide.com Tel: 01675 462424 Station Road, Birmingham, Coleshill B46 1JY

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Air Liquide UK have extensive experience in the Biotechnology and Laboratory and Analysis field, offering a wide range of products and services to help you increase yield, improve product quality and reduce production hazards. We are constantly looking at ways we can help our customers improve quality, safety and costs. We work closely with our customers to ensure they can concentrate and focus on their core business, leaving their production and laboratory gases, dry ice and equipment requirements to Air Liquide UK.

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Akela Consultancy Ltd www.akelacl.com Tel: 01837 82165 Fax: 01837 880082 Larkworthy Farm Essington North Tawton EX20 2EX

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Alpha Biologics

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Michelle Peake

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www.alphabiologics.com

michelle.peake@alphabiologics .com Tel: 01223 496070

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Fax: 01223 496071

Alpha Biologics are experts in the production of monoclonal antibodies and other recombinant proteins. Our Cambridge labs carry out contract reseach or process development for clients, with seperate suites for work on bacteria, yeast or mammalian cell lines. Services include cell line selection, cell banking, process development in bioreactors or wave bags, product yield optimisation and downstream separation, and protein supply to the client. For those clients requiring GMP conditions, optimised processes can be transferred for onward manufacture in Alpha’s own GMP production facility, or to other plants specified by the client.

Babraham Research Campus, Babraham, Cambridge CB22 3AT

Altacor www.altacor-pharma.com Tel: 01223 421411 Cowley Road, Cambridge CB4 0WS

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AmeyCespa(East)Ltd enquiries@ameycespa.com

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www.ameycespa.com

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Fax: 01223 861013

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Ely Road, Waterbeach, Cambridge CB25 9PG

Tel: 01223 815477

AmeyCespa offers a comprehensive and innovative approach to waste management, tailoring sustainable waste solutions to our customers’ needs. We provide a complete waste management service for businesses, local authorities and the general public, including recycling, composting and energy recovery. Through our 500-acre Cambridgeshire site, we process over 300,000 tonnes of waste each year and compost or recycle over half of this. Our clients include councils, schools, health and social care providers, and local businesses. Our innovative ‘in-vessel’ composting facility processes a variety of biodegradable wastes including green/garden waste, catering waste, commercial growers’ waste, paper and cardboard, producing high quality soil improver.

We operate a recycling facility for construction, demolition and general skip waste, and offer collection services which incorporate recycling of glass, cans, plastic bottles, food waste, paper and cardboard to commercial organisations.

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Amies Innovation Ltd Bill Johnson bill@amiesplastics.co.uk www.amiesinnovation.co.uk Tel: 01246 568046 07872 130061 Fax: 01604 570770 Amies Innovation Limited, Quarry Lane, Chatsworth Road, Chesterfield S40 3AT

One Nucleus Directory 2012

We are an EN13485 and ISO9001 registered engineering injection moulder manufacturing components in mid range to high end polymers for mainstream and safety critical applications. As well as supplying components with built-in anti microbial properties, we already work in the point-of-care testing space. We are keen to engage with partners commercialising products for which we could help optimise material selection and design for manufacture, source tooling and go on to injection mould production requirements. Our facilities include a white room for the more economical processing of components not calling for full cleanroom manufacture. And we now offer 2 shot moulding capability for making components such as instrument housings in plastic with elastomer inserts for greater user comfort.

Amphora Research Systems Rob Swan robs@amphora-research.com www.amphora-research.com Tel: 01344 381983

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Amphora is one of the worldâ&#x20AC;&#x2122;s leading suppliers of replacements for the Bound Laboratory Notebook. Our solutions are in use around the world by companies large and small, helping scientists work better, collaborate easily with each other, and protect their inventions. At Amphora we focus on replacing the bound paper notebook with a searchable, shareable and secure electronic version. In the process we make sure that you donâ&#x20AC;&#x2122;t compromise your patent protection, in fact our customers and their lawyers report that they end up with much better IP records.

PO Box 3940, Bracknell, RG42 2XN

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AMRI Heidi Kingdon Jones heidi.kingdonjones@amriglobal .com www.amriglobal.com Mostyn Rd, Holywell, Flintshire CH89DN

AMRI is a global contract research and manufacturing organization with more than twenty years experience providing customers fully integrated discovery, development, and manufacturing services. AMRI provides contract services to companies in the pharmaceutical, specialty chemical, biotechnology, cosmetic, agriculture, and food/beverage industries, as well as not-for-profit organizations, universities, and medical institutions. AMRI provides a broad range of services and technologies to provide flexible and strategic support for discovery and development of pharmaceutical products and the manufacturing of API and drug product for existing and experimental new drugs, providing geographic proximity, and creative budgetary solutions. At AMRI, project managers are geographically assigned to projects, providing the customer with one primary point of contact. Project management at AMRI compresses timelines, maintaining quality and reducing costs. Since 1991, AMRI has steadily expanded and globalized its contract services platform beyond its major U.S. facilities through a combination of acquisitions and green field initiatives, which include a process development and large-scale manufacturing in the United Kingdom; a medicinal chemistry and custom synthesis in Hungary; a chemical development and cGMP scale up and manufacturing in India; a medicinal chemistry and in vitro biology in Singapore; and an aseptic fill and finish capabilities in Burlington, Mass.

Tel: 01235 232100 184 Milton Park, Abingdon, OX14 4SE

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AMS Biotechnology (Europe) Ltd www.amsbio.com

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Founded in 1987, amsbio is recognised as a leading international source of unique & innovative products & custom services for life sciences research. The amsbio range includes over 68,000 polyclonal & monoclonal antibodies, peptides, recombinant proteins, extracellular matrix, molecular detection reagents, & tissue DNA, RNA, protein & microarray products. Key research areas include: apoptosis, cell invasion & migration, cell signaling, DNA damage, electrophoresis, glycobiology, posttranslational modification & stem cell biology.

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AnaBioTec Daniel Jones daniel.jones@anabiotec.com Tel: 07715 352165 +32 9 241 5649 www.anabiotec.com Reibroekstraat 13, Evergem, Belgium 9940

AnaBioTec is a cGMP compliant contract laboratory providing physical, chemical, biochemical and microbiological analytical services to the pharmaceutical and biopharmaceutical industries. Established in 1998, AnaBioTec provides a high quality and responsive service to clients of all sizes across Europe and in the US from its premises in Ghent, Belgium.

Contract services include method development, method validation, stability studies and release testing for both early and later phases of development, and for both large and small molecules. The laboratories have been successfully inspected by the FDA and the European Authorities. AnaBioTec offers a skilled and committed team of analysts and scientists with a wide range of experience and knowledge. A dedicated Project Manager is assigned to your project throughout its duration, ensuring frequent feedback on project progress and a flexible and timely response. Please visit our website at www.anabiotec.com, or contact: Daniel Jones, Business Development Manager. Tel: +44 7715 352165; e-mail: daniel.jones@anabiotec.com

Apitope Technology (Bristol) Ltd

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Dr Hayley French

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www.apitope.com Tel: 01173 707720

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Innovation Centre, Bristol & Bath Science Park, Dirac Crescent, Emersons Green Bristol BS16 7FR

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Applied Medical Technology Ltd www.applied-medical.co.uk Tel: 01223 420415 4 Kings Court, Kirkwood Road, Cambridge CB4 2PF

Applied Medical Technologies Ltd based in Cambridge, is the UKs leading supplier of ambulatory systems for the continuous administration of drugs for a variety of clinical purposes. We also offer the most comprehensive range of high quality subcutaneous infusion administration sets. We develop bespoke solutions for therapies that benefit from a non-intravenous route of drug delivery by providing the most reliable, comfortable and convenient disposable systems available. Therapies which benefit from our technologies include: - Oncology - Pain relief - Pulmonary Hypertension - Primary Immunodeficiency - Intrathecal Infusion - Asthma - Thallasemia - Hormone Therapy - Rehydration

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Aptiv Solutions

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www.aptivsolutions.com

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Hemel One, Boundary Way, Hemel Hempstead HP2 7YU

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Tel: 01442 283658

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Arco Ltd www.arco.co.uk Arco House, Easlea Road, Moreton Hall Industrial Estate, Bury St Edmunds IP32 7BY

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Arco is the UKâ&#x20AC;&#x2122;s leading supplier of personal protective equipment, workwear and workplace safety products.

As such it is widely recognised as a provider of expert advice, services and safety solutions for businesses in every market sector. Founded in 1884, the Hull-based, 4th generation family business now has over 110,000 customers. Through its team of product specialists, its product catalogue and a rapidly expanding 40-strong branch network, Arco offers a world-class range of quality assured, branded and own-brand products, carefully selected from ethically compliant suppliers. Products include personal protective equipment, clothing including front and back-of-house career wear, footwear, gloves, workplace safety and hygiene products. Arco is dedicated to its Corporate Social Responsibility policy and continually demonstrates its support of local business communities and charitable organisations. In 2005, Arco became a member of the BITC Percent Club by donating 1% of pre-tax profits to charities. In 2007, Arco became a member of the Ethical Trading Initiative (ETI).

Arecor Ltd Sheridan Cook

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info@arecor.com

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Tel: 01223 426060

www.arecor.com

Arecor Ltd was established to provide formulation solutions to pharmaceutical and biotech companies developing drugs, vaccines, medical devices and diagnostics. Proteins and vaccines are often fragile entities, and stability can represent significant constraints in the development of new products and extending the use of existing products. Arecor has developed Arestatâ&#x201E;˘, a patented set of tools for stabilization, to enable the presentation of labile biologicals as stable aqueous formulations even at high concentrations or in situations where cold storage is not practical or desirable.

Fax: 01223 423411

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2 Cambridge Science Park, Milton Road, Cambridge CB4 0FE

Argo Consulting Stephen Lang stephenm.lang@btinternet.com www.argoconsulting.com Tel: 01799 513 209 Fax: 01799 513 209 Oak Cottage, Catmere End, Saffron Walden CB11 4XG

One Nucleus Directory 2012

Argo Consulting specialises in providing the full range of Business Development services to the Medtech industry, namely: identification of optimal development strategies, identifying and acquiring suitable companies or technology, selling or licensing technology to larger companies. I will work with you to identify the right strategic option, identify and work with partners, conduct valuations, manage diligence investigations, negotiate and draft agreements and assist with implementation of the deal. I bring over 20 years of expertise and experiences from many deals to bear on each Business Development project. I also present training courses in the art and science of negotiation.

Armari Ltd

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www.armari.com

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Tel: 01923 225 550 5 Woodshots Meadow, Croxley Green Business Park, Watford WD18 8YS

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assm (Asset and Systems Support Management)

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John Moore

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john@assetandsystems.co.uk

Extensive experience in the planning of total cost of ownership for physical assets. Asset support design and implementaton with cost controls to match business focus

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www.assetandsystems.co.uk/ Tel: 01763 247681

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The Causeway, Bassingbourn, Royston SG8 5JD

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Associates of Cape Cod mchilds@acciuk.co.uk Mark Childs www.acciuk.co.uk Tel: 0151 5477444 Fax: 0151 5477400 Associates of Cape Cod, Deacon Park, Moorgate Road, Knowsley, Liverpool L33 7RX

Associates of Cape Cod, Inc. (ACC), is one of the world’s largest manufacturers of products developed to detect and quantify gram-negative bacterial endotoxins and (1?3)-ß-D-glucans. Our products are used worldwide by leading pharmaceutical and medical device companies to ensure the safety of their parenteral drugs, biological products and medical devices. Our goal is to provide the best products and services, as well as the best technical support and customer service, in our industry to enhance the productivity and efficiency of all our customers.

a.jeffery@aston.ac.uk www.aston.ac.uk/bpu Tel: 0121 2043366 Fax: 0121 2045152 Business Partnership Unit, Aston Triangle, Birmingham B4 7ET

ziggy.kovacs@astridbio.com www.astridbio.com Tel: +36 52533173

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Aston University’s School of Life Sciences pursues interdisciplinary research in Biomedical sciences, Pharmacy, Neurosciences, Vision sciences, Audiology and Psychology at the interface between the laboratory and the clinic.

Incorporating the other Schools across the University, Aston’s Centre for Healthy Ageing takes a multidisciplinary approach to address five themes, ageing metabolism, ageing eye, ageing mind, ageing & healing and ageing lives to understand and prevent age-related decline. The University also recently opened the Aston Brain Centre, which is an integrated research environment for the study of the brain and neurodevelopment in health and disease. It houses MEG (and a paediatric version is in development), 3-tesla MRI, EEG and sleep research laboratories with a particular interest in diagnosis and drug therapies. Diseases studied include epilepsy, dyslexia, autism, attention deficit hyperactivity disorder.

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Astrid Research Inc. Ziggy Kovacs

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Aston University - Business Partnership Unit Dr Angela Jeffery, Business Development Manager

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V Astrid is one of the largest, privately held bioinformatics companies in Europe with offices in Austria and Hungary. Our focus is data management and analysis for genomics research - utilizing our core competences in mathematics and information technology. Our clients include academic research institutes, pharmaceutical and biotech companies, who are seeking comprehensive IT solutions for diagnostic marker and therapeutic target identification.

Fax: +36 52533174

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Csapo u. 42, Debrecen 4029 Hungary

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Atlantic Accelerator Ltd Theodoros Koutroukides, Senior VP info@atlantic-accelerator.co.uk

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www.atlantic-accelerator.co.uk/ Tel: 01223 420 252

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St Johnâ&#x20AC;&#x2122;s Innovation Centre, Cowley Road, Cambridge CB4 0WS

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ATPBio Ltd

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Dr Raman S. Minhas

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raman.minhas@atpbio.com www.atpbio.com Tel: 01858 450341

Formed by a group of seasoned healthcare entrepreneurs, hand-picked service providers and international investor firms, Atlantic Accelerator supports and invests in high value medical solutions addressing unmet medical needs in the hospital and specialist-care environments. Atlantic Accelerator is addressing the cost of patient treatment, using the convergence of pharmaceuticals, devices, diagnostics and ICT technology, accelerating development of improved high value medical solutions for hospital-managed care. Based on an open-innovation philosophy and bringing together a unique group of sector specialists, the Accelerator matches companies developing innovative and potentially disruptive technologies with the expertise they need to accelerate their route to market and time to exit. Through the groupâ&#x20AC;&#x2122;s connections, doors are opened to international investors, customers and potential acquirers.

We provide hands on support for medtech and biotech business development and corporate development.

We act as strategic advisor to companies or interim within the executive team. Professionals from ATPBio have advised biotech and medtech fundings and partnering transactions totaling over $500 million of realised value (actual cash in or exits).

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Bannon Milbourn Ltd milbourn@ntlworld.com

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BARQA www.barqa.com

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Tel: 01473 221411

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3 Wherry Lane, Ipswich IP4 1LG

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Fax: 01473 221412

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base4 innovation ltd www.base4innovation.co.uk Tel: 01223 358652 21 JJ Thomson Ave, Cambridge CB3 0FA

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BARQA is an Association dedicated to informing and advancing its members and provides status and visability for individuals concerned with the quality of research in pharmaceutical, agrochemical and chemical industry sectors. Since its inception in 1977 the Association has grown and developed to reflect regulatory changes, the impact of regulatory inspection and the changing structure and needs of industry.

BBSRC Dr Alex Chaix alex.chaix@bbsrc.ac.uk www.bbsrc.ac.uk/business/ business-index.aspx Tel: 01793 413237 Polaris House, North Star Avenue, Swindon SN2 1UH

A BBSRC invests in world-class bioscience research and training on behalf of the UK public. Our aim is to further scientific knowledge, to promote economic growth, wealth and job creation and to improve quality of life in the UK and beyond. Funded by Government, and with an annual budget of around £445M, we support research and training in universities and strategically funded institutes. BBSRC research and the people we fund are helping society to meet major challenges, including food security, green energy and healthier, longer lives. Our investments underpin important UK economic sectors, such as farming, food, industrial biotechnology and pharmaceuticals. For more information about BBSRC, our science and our impact see: http://www.bbsrc.ac.uk For more information about BBSRC strategically funded institutes see: http://www.bbsrc.ac.uk/institutes.

www.bergenbio.com Tel: 47 53501564 Jonas Lies vei 91, 5009, Bergen Norway

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BerGenBio AS enquiries@bergenbio.com

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BerGenBio AS is a clinical stage biotech focused on cancer biology, tumor micro environment, mechanisms of EMT and drug resistance. Built on a powerful discovery platform, CellSelect, BerGenBio identifies and validates novel drug targets, biomarkers and develops first in class drugs against these targets. BerGenBio lead program BGB324 is a highly selective AXL inhibitor-entering phase 1 in 2012. We are seeking drug discovery partners to develop in risk-reward collaborations first in class therapeutics against our validated novel targets. BerGenBio CRO offers advanced target discovery, validation, biomarkers, genetic dose response profiling, disease modelling, MoA studies, escape pathways and library screening.

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BigBear Communications Ltd

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www.bigbear-comms.com Tel: 01844 296178

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25 Churchwayz, Haddenham HP17 8AB

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Bio Nano Consulting Ltd Dr Mike Fisher mike.fisher@bio-nano-consulting .com www.bio-nano-consulting.com Tel: 020 7396 1050 Fax: 020 7396 1056

Bio Nano Consulting solves practical problems for industry and helps clients develop world-leading research capabilities by accessing our partner universities of UCL, Imperial College and London School of Pharmacy.

BNC proactively manages industry-academic research projects, ensuring projects start in a timely manner, are professionally delivered to commercial standards and deliver to time, cost and quality. Example projects we have successfully delivered are: • Formulation of a phase I oncology drug • Problem solving in manufacturing of a molecular diagnostic system • Mechanism of action for an FDA submission • Assessment of novel detection methods for lateral flow diagnostics • Design of a novel assay system to remove the need for human tissue

www.biobridge.co.uk Tel: 01223 566850 Fax: 01223 470222 45 St Barnabas Road, Cambridge CB1 2BX

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BioBridge Ltd mlloydevans@biobridge.co.uk

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338 Euston Road, London NW1 3BT

Mr. Meredith Lloyd-Evans

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V BioBridge® was founded in 1989 to address challenges to commercialisation for innovations in biosciences.

We help our clients through the entire product chain, discovery development to market entry and maintenance, including due diligence for investors. Our achievements are in all bioscience sectors including human and animal health, medical technology and bioengineering, food, agriculture, general biotechnology and industrial biotechnology (green chemistry, biomass use for natural products, bioenergy and bioremediation). Our clients are public organisations, private companies and innovation-generators such as Universities and research bodies. Current and recent work includes monitoring, expert oversight and support for publicly-funded projects in industrial biotechnology; regulatory strategy for a novel pet food additive; global benchmarking survey for an international animal health industry body; product-finding for pharmaceutical companies; network creation in environment and algal technologies; strategic analysis of GM crops and food regulations; integrating low carbon strategies with life sciences; membership of an EU project CSA MARINEBIOTECH; & product safety and compliance oversight for a biomaterials company.

www.onenucleus.com

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Biocair International Ltd www.biocair.com The Business Centre, Cherry Hinton, Church End, Cambridge CB1 3LB

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BioLauncher Ltd

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Rowan Gardner

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www.biolauncher.com

rowan@biolauncher.com

Tel: 01223 833858

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Biocair operates a specialist logistics service, which focuses solely on the material produced by the pharmaceutical, biotechnology and medical research communities. We have over 20 years’ experience in this field. Biocair is a global organisation, with main offices in Boston USA, Cambridge UK and Osaka JP. We specialise in giving up to date advice on classification and regulatory requirements of hazardous material which can include infectious, toxic, biological, genetically modified and radioactive. We apply the correct procedures, supply all packaging and documentation and fulfil every legal requirement, while planning the most efficient routes globally, including clinical trial management. Biocair offer full temperature control including dry ice, refrigerated (2 to 8°C), ambient, warm and liquid nitrogen. Our staff, including science graduates and regulatory experts, have received training from accredited dangerous goods schools in the classification, documentation, packaging and labelling of hazardous materials

Biolauncher is an expert advisory company that helps growing companies formulate their product, commercial and corporate strategy, prepare for funding and broker relationships. The company also provides technology scouting and evaluation services to companies seeking access to innovation. The company’s services are supported by our proprietary information and analytic system, ShowcaseBio that aggregates commercial life science information from over 350 sources. To find out more about our work with life science companies, investors and public sector bodies visit biolauncher.com

Lower Court, Suite 6C, Copley Hill Business Park, Cambridge CB22 3GN

Bioline Reagents Ltd www.bioline.com Tel: 0208 830 5300

Founded in 1992 and headquartered in London, UK., Bioline is an evolving international company, which develops, manufactures and markets a wide range of specialized bio-research reagents that simplify, accelerate and improve life sciences research.

Fax: 0208 452 2822 Unit 16 The Edge Business Centre, Humber Road, London NW2 6EW

BioMoti Ltd www.biomoti.com Innovation Centre, 42 New Road, London E1 2AX

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BioMoti Ltd is a privately held UK based company engaged in the development of platform drug delivery technologies. In particular, BioMoti focuses on improving the delivery of active agents to the intracellular space.

This is achieved by packaging the drug compounds into functionalised microparticles designed to access the interior of targeted biological cells. BioMoti is currently focussed on improving the delivery of drugs in cancer; helping to increase efficacy and reduce toxicity. Paired with the appropriate pharmaceutical agents, BioMoti technology can form a substantial portion of the worldwide market in the treatment of specific cancers by offering opportunities to target new intracellular mechanisms, reformulate compounds and contribute to the patent extension of marketed drugs. The total oncology market was worth over $66 billion in 2007 and strong doubledigit growth is expected due to increased demand from an ageing population predominantly affected by cancer and the on-going need for innovative medicines.

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Bionow Ltd www.bionow.co.uk Kilburn House, Manchester Science Park, Lloyd Street, North Manchester M15 6SE

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One Nucleus Directory 2012

Bionow is a membership organisation which has been serving the biomedical industry in the North of England since 2000. With strong private sector backgrounds the Bionow team are wholly focused on the needs of businesses. We have a significant track record of assisting businesses, leveraging savings, delivering specialist events and providing bespoke business development functions for our Members. Membership of Bionow can add significant value to your business and increase its development potential.

BioPark William Sprigings info@biopark.co.uk www.biopark.co.uk www.BABSbiomarkerservices .co.uk Tel: 01707 356100 Fax: 01707 356115

A University of Hertfordshire’s Science Park: flexible, realistically-priced laboratory and office accommodation in various configurations for growing technology businesses. Incubator: start-ups and spin-outs welcome. Inward Investment: ideally centred within the research ‘golden triangle’, Cambridge-London-Oxford offering prestigious accommodation for overseas technology businesses intending to establish a base in the UK. Excellent location, close to the railway station, 30 minutes to central London. Near motorway network and around an hour’s drive to Heathrow, Luton and Stansted airports. Professional Service Providers: comprehensive meeting, conference and event facilities including a 66 seat lecture theatre. ‘Open access’ biomarker assay lab - BABS Biomarker Services.

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Broadwater Road, Welwyn Garden City AL7 3AX

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BioPartner.co.uk

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info@biopartner.co.uk www.biopartner.co.uk Tel: 01865 784737 Fax: 01865 521151

Biopartner.co.uk is a UK Government accredited Trade Organisation facilitating international partnering for collaborations with Life Sciences organisations across the UK. BioPartner supports UK SMEs and startups, and signposts organisations worldwide to UK expertise. Biopartner.co.uk organises international biopartnering events, projects and missions, operating both independently and in partnership with the UK government. Members of the BioPartnership Programme benefit from our full range of discounts, enhanced promotion on BioPartner UK Delegations and first refusal on new international opportunities.

The Magdalen Centre, Oxford Science Park, Oxford OX4 4GA

www.biopharma.co.uk/ Biopharma House, Winnall Valley Road, Winchester SO23 0LD

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Biopharma Technology Ltd btl@biopharma.co.uk

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BTL has unparalleled track record in freeze drying diverse and complex products including liposome, foodstuffs, vaccines, cells, nucleic acids, proteins, small molecule APIs, bacteria, various biomaterials and new drug formulations for our customers around the world. Using custom-designed analytical instruments and decades of experience, thermal behaviour of products can be characterised scientifically. This enables formulations to be developed rationally and safe and repeatable cycles calculated development, trial and production size batches.

We also offer small scale batch processing for all applications.

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BioPharmaLogic LLC

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Info@BioPharmaLogic.com

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www.biopharmalogic.com Fax: 01480 773601

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St John’s Innovation Centre, Cowley Road, Cambridge CB4 0WS

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Biosynergy (Europe) Ltd www.biosynergyeurope.com Tel: 01223 579340 12 Pembroke Avenue, Denny Industrial Centre, Waterbeach, Cambridge CB5 9PB

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Contract manufacturer of biologics for immunodiagnostic, bio-pharmaceutical and environmental biotechnology applications. Contract RD; creation, development and optimisation of cell lines; process development and validation; production and purification of proteins (milligram to multi-gram quantities)to enable characterisation, pre-clinical testing, and scale-up for clinical trials. Specialist in hybridoma technology and production/purification of monoclonal antibodies and recombinant proteins from mammalian cell lines. Development of bioassays for environmental monitoring. Microbial and monoclonal antibody-based bioassays for identifying pathogens and determining toxicity of wastewater and groundwater. Technologies: Hollowfibre bioreactors; spinner/roller culture; stirred vessel bioreactors; Affinity, ion-exchange and size exclusion chromatography.

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BIOTEM custom antibodies & services Pierre Peotta info@biotem.co.uk www.biotem-antibody.com Tel: 01223 505 182 Fax: +33 4 76 67 48 86

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5 Queensway, Trumpington Road, Cambridge CB2 8AX UK

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bioteXcel consulting

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Elisabetta Fineschi

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www.biotexcel.com

info@biotexcel.com

Tel: 01933 411702

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PO Box 7619, Higham Ferrers, Rushden NN10 1AW

Expert in immunotechnology, BIOTEM provides customised and high added value services in the field of antibodies and immunoassays design. For more than 30 years, BIOTEM has developed a unique expertise and a large panel of cutting edge proprietary technologies. For most projects BIOTEM is proud to carry out the most relevant strategies and to propose contracts with guaranteed results. (>94% overall project success rate over the last 3 years). Since being created in 1980, BIOTEM has been a first rate partner of pharmaceutical groups, biotechnology companies and academic laboratories for their research, development and production needs.

BIOTEM complies with ISO 9001:2008 quality standards.

bioteXcel consulting is a global life science consultancy providing strategic business development, marketing, interim management, financing advice and technical support services to pharmaceutical and biotech companies.

We use traditional and new sales & marketing technologies and methods including novel lead generation techniques, conferences, our online scientific journal and online television based news & interviews to reach new global audiences. Our multilingual team consists of globally located Product Design, Regulatory Affairs, R&D, Financing, Manufacturing and Business & Marketing professionals; they are ready to help our clients take the next steps in rolling out their products and services to new global markets spanning US, EU, China and India.

Soâ&#x20AC;Ś whether you are new to the Life Science market, have a new service, a new product or want to reach new geographical territories bioteXcel has strategic solutions for you.

BMI SYSTEM contact@bmi-system.com www.bmi-system.com 1 Putney Bridge Approach, London SW6 3JD

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BOC Michael Pott

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Michael.Pott@boc.com

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Tel: 07748 111 441

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The Priestley Centre, Surrey Research Park, Guildford GU2 7XY

www.boconline.co.uk

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Boult Wade Tennant Matthew Spencer mspencer@boult.com www.boult.com Tel: 0207 430 7500 Fax: 0207 430 7600 CPC4, Capital Park, Cambridge Road, Cambridge CB21 5XE

One Nucleus Directory 2012

Boult Wade Tennant is a leading UK and European firm of patent and trade mark attorneys advising on all aspects of intellectual property protection, management and enforcement worldwide. Services include patent drafting, filing and prosecution, EPO oppositions, freedom to operate searches, IP due diligence and infringement opinions. Our Life Science attorneys have expertise in a range of areas of biotechnology and biological chemistry including molecular biology, genomics, bioinformatics, diagnostics, array technology, human genetics, stem cells, pharmaceuticals, biosensors, drug delivery systems, fermentation and biofuel inventions, DNA sequencing techniques, lab-in-chip technology, vaccines, and herbal medicines. The Boult Wade Tennant Cambridge patent and trade mark teams are experts in the fields of Biotechnology and Life Sciences; High Tech and Electrical; Engineering and Designs; Chemical and Materials; and Trade Marks and Domain Names.

Bridge Partners Andrew Glover info@bridgepartners.co.uk www.bridgepartners.co.uk Tel: 01223 750150 Fax: 01223 750110

A Bridge Partners are an information and communications technology (ICT) support services company based in Cambridge. Bridge Partners specialise in helping small to medium-sized organisations to get the best from their information and communications technology. If you are starting from scratch, we can advise you on what to buy to support your business objectives. Where you have already made an investment in ICT, we will show you how to use it for maximum business benefit and support your systems on an ongoing basis. We also provide dedicated internet connections, specialising in provision to Business Parks and multi-tenanted buildings. We also provide hosting. This covers email, backup, disaster recovery solutions, servers as well as website and applications.

St John’s Innovation Centre, Cowley Road, Cambridge CB4 0WS

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Bridgehead International

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Timothy Fitzgerald

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info@bridgehead.com www.bridgehead.com Tel: 01664 503700 Fax: 01664 503705 Pera Innovation Park, Nottingham Road, Melton Mowbray LE13 0PB

Bridgehead International, a leading strategic healthcare consultancy, is a global provider of pricing, reimbursement, health economics and market access support and a preferred partner for many major companies in the pharmaceutical, medical technology and related financial sectors. Bridgehead provides a broad range of global market access services, including: • Market access strategy • Pricing assessment and strategy • Payer research • KOL, Physician and patient research • Health economic assessment and modelling • Core reimbursement dossiers • Value propositions and messaging • Product Lifecycle and portfolio strategy • Market access due diligence Bridgehead offers a unique mix of scientific, technical, payer and professional consultancy experience and expertise. Bridgehead also continues to be a respected leader in the due diligence space for initial public offerings, licensing and mergers and acquisitions.

jw@bb-ip.com www.bb-ip.com Tel: 01892 510600 1 Boyne Park, Tunbridge Wells TN4 8EL

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Brookes Batchellor LLP Joanna Winwood

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Brookes Batchellor is a leading firm of UK and European patent and trade mark attorneys specialising in technical fields such as biotechnology, pharmaceuticals, chemistry, electronics, software, physics and mechanical engineering, and in protecting your commercial identity – your brands, trading names and logos. Our clients at Brookes Batchellor range from start-up technology companies and universities to global organisations in the UK, US, Japan and elsewhere. We also assist overseas attorneys and corporations on specific European matters. We provide clear, practical and commercial advice. Our life sciences team has expertise in a wide range of biotechnology techniques, including bioinformatics, diagnostics, stem cell research and biosensors, along with pharmaceuticals, medical devices and drug delivery systems.

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BSG Team Ventures

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www.teamventures.co.uk

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St Andrews House, 90 St Andrews Road, Cambridge CB4 1DL

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Cambridge BioScience Ltd support@bioscience.co.uk www.bioscience.co.uk Tel: 01223 316 855 Fax: 01954 781 323

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Cambridge Bioscience is a leading distributor of life science products with a passion for bringing new and exciting technologies to researchers. Working with over forty specialist suppliers around the world, we offer an innovative, extensive and diverse range of over 400,000 products supporting research in the areas of cancer, epigenetics, inflammation, innate and adaptive immunity, molecular biology, neuroscience, regenerative medicine and much more.

Munro House, Trafalgar Way Bar Hill, Cambridge CB23 8SQ

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Cambridge Cognition Ltd www.cantab.com Tunbridge Court, Tunbridge Lane, Bottisham, Cambridge CB25 9TU

Cambridge Cognition Ltd (CCL) develops and markets computerised cognitive testing software under the CANTAB™ brand name. CCL provides software to Academic Research institutions around the world and is the market leader in this sector. CCL is also a leading provider of specialist Cognitive testing products and services to the world-wide pharmaceutical industry, with experience in all phases of drug development in global studies and counts many of the world’s top 15 pharmaceutical companies as clients. CCL has offices in Bottisham outside Cambridge and Cambridge Mass.

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Cambridge Design Partnership LLP

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www.cambridge-design.co.uk

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The Long Barn, Church Road, Toft, Cambridge CB23 2RF

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Tel: 01223 264428

Cambridge Design Partnership works with both industry leaders and early stage companies to develop their innovative products for the healthcare market. In addition to product design and user testing, our multidisciplinary team provides expertise in electro- and biomechanics, microengineering, optics, digital imaging, ergonomics, physiology and biochemistry. We support clients from first concepts through user trials to regulatory approval and manufacture. We specialise in diagnostics, drug delivery, minimally-invasive surgery, imaging, wellbeing and exercise science. We operate focus groups with health professionals at all levels from NHS Trusts across the country, to gain an in-depth understanding for each product. This has been pivotal to our clients’ success. Bring us your challenging projects. To hear how we have developed products for our clients, please give us a call!

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Cambridge Employment Law LLP Eleanor Freeman eleanor.freeman@cambridge employmentlaw.com Tel: 01223 656952

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Mob: 07834 362283

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Stratford House, Ousden, Newmarket CB8 8TN

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Cambridge Enterprise University of Cambridge Shirley Jamieson Shirley.Jamieson@enterprise. cam.ac.uk www.enterprise.cam.ac.uk Tel: 01223 760339

Cambridge Enterprise is responsible for the commercialisation of University of Cambridge intellectual property and is a wholly owned subsidiary of the University. Activities include management and licensing of intellectual property and patents, proof of concept funding and support for University staff and research groups wishing to provide expert advice or facilities to public and private sector organisations. Cambridge Enterprise provides access to angel and early stage capital through the Cambridge Enterprise Seed Funds and Cambridge Enterprise Venture Partners, and offers business planning, mentoring and other related programmes.

Fax: 01223 763753 Hauser Forum, 3 Charles Babbage Road, Cambridge CB3 0GT

Cambridge Healthcare and Biotech Ltd www.chandb.com Tel: 01223 839 503 Fax: 0870 751 7505 Little Chesterford CB10 1XL

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Cambridge Employment Law LLP is a boutique employment law practice, advising both employers and employees. We pride ourselves on giving an outstanding personal service to our clients. Our size and the specialist nature of our practice mean that you will have a personal relationship with a lawyer who understands your business and cares about its success. Our advice is always commercial and pragmatic, based on our lawyers’ many years of experience and technical expertise. Eleanor Freeman has a particular interest in the biomedical sector. Her experience in the common challenges facing start-ups and high-growth companies is balanced with significant expertise representing global pharmaceuticals in all employment-related matters.

Eleanor also runs the training for the One Nucleus HR Special Interest Group.

One Nucleus Directory 2012

Cambridge Medical Innovations Ltd www.cam-medical.com Milton Road, Cambridge CB4 0GJ

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Cambridge Medical Innovations Ltd (CMI, part of Inverness Medical Innovations Inc) is a dynamic R&D organisation specialising in the development of medical diagnostic devices. CMI is dedicated to developing a series of devices that will help in the diagnosis of diseases and enable more efficient monitoring of human health. Our mission is to develop the diagnostics devices to be sold worldwide. The company is located at the Cambridge Science Park, Cambridge, UK. We have access to a number of biosensor platforms; our core technology is based on robust label-free sensing exploiting high frequency acoustics to specifically diagnose diseases. The systems can directly detect a range of molecules, bacteria and viruses in both crude samples and complex matrices with minimal need for sample processing or purification. This is achieved by attaching a specific target receptor to the surface of an acoustic resonator, using one of a variety of coupling chemistries, followed by delivery of a sample via a micro fluidic flow-based system. The resonant acoustic signal indicates not only the presence of target molecules but also their concentration in the sample.

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Cambridge Medipark Ltd

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www.cambridge-biomedical.com

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Tel: 01277 697152

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Fax: 01277 690600 c/o Countryside Properties (Special Projects) Ltd, Countryside House, The Drive, Brentwood CM13 3AT

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Cambridge Network Ltd Claire Ruskin, CEO claire.ruskin@cambridgenetwork .co.uk www.cambridgenetwork.co.uk Tel: 01223 300148 The Entrepreneurship Centre, The Hauser Forum, 3 Charles Babbage Road, Cambridge CB3 0GT

Founded in 1998, Cambridge Network is a membership organisation focused on creating connections between business and academia. With talent and expertise in abundance in this vibrant, world-renowned high technology cluster, we want to attract more talent to join us and to promote the best that Cambridge can offer. The Network works with start-ups, SMEs and global corporations to collaborate for shared success and to be better by: • sharing learning – training opportunities through the Learning Collaboration • operating a varied events schedule • offering cambridgenetwork.co.uk as a channel for members to promote themselves, their products/services and activities • working together to attract and retain talented employees • providing a directory resource of businesses and academia Bringing people together for shared success.

bjacoby@cambridge-ra.com Tel: 01223 240353 2 Rotherwick Way, Cambridge CB18RX

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Cambridge RA Ltd Ben Jacoby PhD

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Cambridge RA provides regulatory and strategic guidance on EU and US issues to clients in the diagnostic, pharmaceutical and healthcare industries who are bringing innovative products to market. Clients include startup companies and established multi-nationals. With extensive experience of regulatory affairs at organisations including Johnson & Johnson (Ortho-Clinical Diagnostics), a range of services are provided including: • Regulatory strategy and planning for EU, US and international markets • European in-vitro diagnostic (IVD) and medical device regulations / CE marking • US FDA pre-IDE process and 510(k) • Assessment of clinical validation requirements • Preparation / review of technical documentation • Regulatory Authority liaison • European environmental regulation • Companion diagnostics (personalized medicine) • Medical device labeling • Field Safety Corrective Action (recall)

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Cambridge Regulatory Services Ltd Karen James www.cambreg.co.uk 2 Cabot House, Compass Point Business Park, St Ives PE27 5JL

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Cambreg has been providing regulatory solutions to pharmaceutical and biotech companies for more than 11 years. Offering a complete portfolio of regulatory services (advice, dossier preparation, regulatory procedure management and ad hoc support); Cambreg has satisfied over 200 clients worldwide, including those from emerging markets. The multicultural, highly experienced team helps clients at any stage in the lifecycle of their product from R&D, through registration, to the market and beyond. Continuing to stay ahead of the game, Cambreg offers clients a commercially focused service. Co-Director Dr Mike James, an ex-health authority regulator with more than 20 years experience in the industry, specializes in the field of biotechnology.

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Cambridge Science Park www.cambridgesciencepark.co.uk Tel: 01223 559331 c/o Bidwells, Trumpington Road, Cambridge CB2 9LD

Established by Trinity College in 1970, Cambridge Science Park is the UK’s oldest and most prestigious science park. Now home to over 100 companies and 1,650,000 sq ft of buildings, Cambridge Science Park continues to attract new businesses, from small start-ups and spin-outs to subsidiaries of multinational corporations. For further information please visit www.cambridgesciencepark.co.uk

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Cambridge Wireless Ltd

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www.cambridgewireless.co.uk

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St John’s Innovation Centre, Cowley Road, Cambridge CB4 0WS

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Tel: 01223 422 365

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Cambridge Wireless is a leading industry forum and vibrant community with a rapidly expanding network of companies actively involved in the development and application of wireless technologies. In addition to high level networking dinners, educational events and business development activities, Cambridge Wireless runs an annual Future of Wireless International Conference along with the Discovering Start-Ups initiative to support emerging, innovative wireless companies. Over 15 Special Interest Groups focused on specific technologies and market sectors, also provide opportunities for members to meet, form partnerships to exploit new commercial opportunities, and share knowledge and information about the latest industry trends and hot topics. Cambridge Wireless has partnerships with other leading industry clusters and organisations around the world to extend its international reach and to keep members up to date with the latest global developments and business opportunities. For more information, please visit: www.cambridgewireless.co.uk

Campbell Charles Associates (2000) Ltd Dr Ignazio Di Giovanna i.digiovanna@cca2000.co.uk www.cca2000.co.uk Tel: 01932 869933

Trials Without The Tribulations: Campbell Charles Associates has a reputation for quality, timeliness and costeffectiveness. We aim to provide sponsors with the commitment they would expect from their own clinical research team. We provide a full service CRO or perform individual tasks. CCA has a loyal client base and a high rate of return business. We are a member of PSN - an international network of highly qualified, owner-driven CROs, delivering high quality clinical research services on a multinational scale (www.psnglobal.org).

Fax: 01932 869944 48 Station Road, Stok D’Abernon KT11 3BN

Canadian High Commission caroline.martin@international .gc.ca amir.golbang@international.gc.ca www.dfait-maeci.gc.ca/london Tel: 020 7258 6363 / 6643 Fax: 020 7258 6384 Commercial/Economic Division.

Macdonald House, 1 Grosvenor Square, London W1K 4AB

The UK is by far Canada’s most important commercial partner in Europe and, from a global perspective, ranks second only to the United States. Two-way trade between Canada and UK was valued at more than £ 16.5 billion in 2010 . The UK ranks third in Foreign Direct Investment (FDI), with UK FDI stock in Canada valued at £26 billion in 2010 . The UK is also Canada’s second largest science & technology partner worldwide, with over 40% of S&T collaborations being in the field of biomedical and clinical research. The Commercial and Economic Division of the Canadian High Commission in London works with Canadian companies, universities and research institutes that are seeking market opportunities, collaborative R&D partnerships or technology transfer deals in the UK. We also offer confidential advice and service to UK companies interested in investing in Canada or in finding collaborative opportunities with Canadian partners.

Capella Recruitment Lorraine Fernandez, info@capella-recruitment.co.uk www.capella-recruitment.co.uk Tel: 01223 721080 Fax: 01223 574689 23 City Road, Cambridge CB1 1DP UK

One Nucleus Directory 2012

Capella Recruitment Limited, a dynamic recruitment consultancy, was established in 1997 and benefits from over 25 years experience gained from staff working in Cambridge and Sydney, Australia. Based in central Cambridge, we specialise in recruiting office support staff for organisations in and around the city of Cambridge. We are preferred suppliers to organisations such as CSR, Genzyme, King’s College, Eversheds & TTP. It is important to us to build strong honest relations with both our candidates and clients alike; whether its offering guidance and advice on taking the next step in your career or making sure you have the best possible person in the job, at Capella, we listen.

Carbogen Amcis AG info@carbogen-amcis.com www.carbogen-amcis.com

A We provide Innovative Chemistry Solutions to address complex chemistry issues through our state-of the art facilities, procedures and most importantly our staff. Specialist areas include chromatography, analytics, microreactor technology and dedicated High Potency services.

These services combined with our flexible production infrastructure allow us to solve complex, development, scale-up and production issues in a cost effective and timely manner.

CARBOGEN AMCIS AG is owned by Dishman Pharmaceuticals and Chemicals, Limited (http://www. dishmangroup.com).

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Carpmaels & Ransford email@carpmaels.com www.carpmaels.com Tel: 020 7242 8692 Fax: 020 7405 4166 One Southampton Row, London WC1B 5HA

Patent and Trade Mark Attorneys Based in London, with an office in Munich. The first UK patent firm, Carpmaels & Ransford has been at the vanguard of intellectual property for over 200 years. Our pioneering roots in London now extend to Munich and around the globe with long-standing client relationships in the USA, Japan and across Europe.

Expertise across all aspects of intellectual property law and across a very broad base of technical disciplines.

Specialist patent teams: Biotechnology Team, Chemistry & Pharmaceuticals Team, Supplementary Protection Certificates Team, Electrical & Mechanical Engineering Team, Electronics, Software & IT Team Superb depth of knowledge in chemistry, biochemistry, molecular biology, physics, electronics, engineering and computer science.

Immersed in biotechnology since the industryâ&#x20AC;&#x2122;s inception.

solutions@catalent.com www.catalent.com

From drug and biologic development services to delivery technologies to supply solutions, we are the catalyst for your success. With over 75 years of experience, we have the deepest expertise, the broadest offerings, and the most innovative technologies to help you get more molecules to market faster, enhance product performance, and provide superior, reliable manufacturing and packaging results.

Tel: +01 888 765 8 8466

www.cfcunderwriting.com Tel: 020 7220 8500 Fax: 020 7220 8501

Established in 2000, we are a Lloyds insurance underwriting agency. We focus on niche business sectors, such as Life Science, Technology, Media and Recruitment, providing cover for SME businesses in 35 countries around the world. In the Life Science sector, we provide innovative insurance packages for drug discovery companies, medical devices, CROs, CMOs, contract research service providers, regulatory affairs and other scientific researchers and consultants. Our policies are designed to be flexible and to address the needs of companies throughout their life-cycle, from start up / spin out, through clinical trials to product approval. In 2010 our approach won the acclaim of our peers, when we were voted Insurance Underwriter of the Year Award. For more information on CFC and what we can do for you, please contact your insurance broker.

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Chempetitive Group Tel: 0203 159 4145

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85 Gracechurch Street, London EC3V 0AA

www.chempetitive.com

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CFC Underwriting Ltd atamworth@cfcunderwriting. com

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14 Schoolhouse Road, Somerset, NJ 08873

Andrew Tamworth

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Catalent Pharma Solutions Patricia McGee

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V Chempetitive Group is a marketing communication agency focused on the life science industry. We work with companies small and large, all around the globe, developing campaigns that build brands and generate revenues.

20 Hanover Square, London W1S 1JY

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Chesterford Research Park Katherine Maguire

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km.chesterfordrp@btinternet. com

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www.chesterfordresearchpark. com

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Tel: 01799 532252 Fax: 01799 531669

Set in 250 acres of open parkland within the South Cambridgeshire Biotech Cluster, Chesterford Research Park provides a secure and relaxed working environment for R&D companies of all sizes wanting to be positioned at the epicentre of UK drug discovery. It is not only an established development, but also a growing community.

The vision for the Park was to create high-quality, state-of-the-art laboratory and office space specifically designed for research and biotech companies at all stages of their life cycle. Now in its twelfth year that vision is fast becoming reality as the Park continues to attract leading R&D companies. On completion, it will comprise 600,000 square feet of R&D facilities within a low-density, landscaped environment served by state-of-theart amenities. The central facilities building at the Park, The Nucleus, sets new standards for the provision of amenities on science park developments, including state-of-the-art conferencing facilities, health club, shop, restaurant and café bar.

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Little Chesterford, Saffron Walden CB10 1XL

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Chromous Biotech (UK) Ltd.

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Nahush Karnataki nahush@chromous.com www.chromous.com Tel: 020 3170 8438 Fax: 020 3008 6161 1 Lyric Square, Hammersmith, London W6 0NB

CINETIQUE Translations info@cinetique.co.uk www.cinetique.co.uk Tel: 0161 2445707

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bioassays@cisbio.com www.htrf.com

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Fax: 33 (0)4 66 79 67 05

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Parc Marcel Boiteux, BP 84175, 30204 Bagnols-sur-Ceze, Cedex France

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Tel: 33 (0)4 66 79 67 05

CiToxLAB Desmond Cave desmond.cave@citoxlab.com www.citox.com Tel: 01368 860 398

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Fax: 01368 860398 07771 864986

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BP 563, Evreux Cedex, 27005 France

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A leading producer of multilingual communications in Science, Technology and Engineering. We provide translation and interpreting services in any combination of languages and assist our clients’ integration into local markets.

Working exclusively with experienced medical/technical translators, consultants and researchers maintaining exceptional language skills, we offer leading quality translation/localization services.

We specialise in: • Manufacturing • Technology • Medicine • Pharmaceuticals • Life sciences • New technologies• Environmental technology We translate: • Websites • User interfaces • Conference publications • Presentations • Training modules • Installation/operating/maintenance manuals • Patents and claims • MSDS

Cisbio Bioassays

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Chromous biotech is dedicated and focussed in 3 domains: 1. Contract Research Services: With lot of passion for customer satisfaction, we undertake customised projects in domains of Gene Expression and Protein purification, Gene engineering, Metagenomics, Genotyping, Plant research and other allied areas. 2.

Manufacturing of reagents: This is to bolster research through innovative yet cost effective products in Molecular Biology and Genomics. 3. Research: Working on independent Research projects through funding. With resounding success, we are expanding our portfolio in Molecular Diagnostics. Chromous Biotech UK Ltd is a wholly owned subsidiary of Chromous Biotech Pvt. Ltd., which is state-of- the- art facility with ISO 9001- 2008 certification, based in Bengaluru, India.

One Nucleus Directory 2012

The CiToxLAB Group, created through the merger of CiT and LAB Research, offers a comprehensive range of pre-clinical and specialty safety evaluation services from four facilities in France, Canada, Denmark and Hungary. CiToxLAB offers all aspects of pre-clinical drug development, including safety pharmacology, pharmacogenomics, genetic toxicology, reproductive studies. We cover all species including primates, transgenic animals and mini-pigs and a study length from acute to carcinogenicity. Dose routes also include, inhalation, continuous infusion and of course dermal in mini-pigs. We specialise in providing a personal, bespoke service to our clients, however big or small. Contact our team of experts: www.citoxlab.com

Clinical Network Services (CNS) Pty Ltd Russell Neal cns@clinical.net.au www.clinical.net.au Tel: +61 (0)7 3719 6000 Fax: +61 (0)7 3719 6011 Level 4, 88 Jephson St Toowong, Queensland, 4066 Australia

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Clinical Network Services (CNS) Pty Ltd is a Clinical Research Organisation (CRO) specialising in the planning and implementation of Phase I & II clinical trials in Australia and New Zealand. As an established, niche CRO serving the needs of SME biotech companies, we have a deep understanding of the commercial and scientific challenges that our clients face. CNS provides its biotech clients with the full range of Phase I and Phase II clinical trial services under the “Fast2First” brand and now offers “BioDesk”, a bespoke product development and regulatory planning service which helps our clients efficiently enter the clinic with their lead candidate for the first time and realise commercial goals earlier. With over 12 years experience in early stage clinical trial management, CNS is one of the most experienced providers within the Australian market and a partner of choice for biotech companies from home and abroad.

BioPark, Broadwater Road, Welwyn Garden City AL7 3AX

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CMP Therapeutics www.cmptherapeutics.com

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The company is developing natural products as intranasal devices and for functional food. Completed phase II clinical trails in seasonal allergy.

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Competitive Drug Development International Ltd info@cddi.co solutions@cddi.co www.cddi.co Tel: 0207 792 6845

We are an international biotechnology and pharmaceutical consulting company, led by a full time core management team of senior people who have developed more than 30 products globally from discovery to market. Our Managing Partners personally direct a global network of people that cover a wide range of drug development expertise with skills to operate in all project areas. Since formation, we have worked with both large pharma and small biotechs, as well as with investment companies.

3 Courtnell Street, London W2 5BU UK

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Confluence Tax LLP

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www.confluencetax.co.uk

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Tel: 01223 243971 Building 14A, The Michael Young Centre, Purbeck Road, Cambridge CB2 8HN

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Constellation Technologies Ltd www.constellationtechnologies. com Tel: 01295 778275 Rutherford Appleton Lab, Harwell Innovation Campus, Didcot OX11 0QX

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Constellation provides bioinformatics IT products and services on the “cloud” to Pharma and Biotech companies using technology developed at CERN and used widely. Applications are usually large data compute and storage services/products; they include data – accessing, management and long term storage, and; compute resources – access to many thousands of cores. Specific applications are any that involve IT expertise and resources but include specifically 1. Gene sequence analysis (human, animal, plant) 2. Large data set mining (useful information from large data sets) 3. Data manipulation using statistical analysis packages Advantages to customers are; 1. Cost reduction (outsource savings)

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Core Cambridge www.core-cambridge.com Tel: 01223 429998 Unit K, Trinity Hall Farm Estate, Nuffield Road, Cambridge CB4 1TG

Core Cambridge is a centre of excellence for injury rehabilitation and the development of athletic performance.

Our unique blend of therapy, coaching and facilities can free you from injury faster than you thought possible, and can develop you physically to levels that you never thought you’d be able to achieve – whether that’s improving your long-term health or competing at an international level.

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Covance Clinical Development

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www.covance.com

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7 Roxborough Way, Maidenhead SL6 3UD

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Tel: 01628 543419

Covance Inc., with headquarters in Princeton, New Jersey, is one of the world’s largest and most comprehensive drug development services companies with global operations in 18 countries, and approximately 6,700 employees worldwide. Covance provides innovative solutions to your drug development challenges, enabling you to make crucial decisions, maximise economic objectives and speed time to market. With expertise and experience in every phase of drug development and the ability to conduct drug trials around the world, Covance is a recognised industry leader. Services include all aspects of preclinical and early clinical testing (toxicology, pharmacology and DMPK), and comprehensive clinical trial management services from phase I-IV.

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Covington and Burling LLP www.cov.com Tel: 020 7067 2040 265 Strand, London WC2R 1BH

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Cyprotex Discovery www.cyprotex.com

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Tel: 01625 505 160

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15 Beech Lane, Macclesfield SK10 2DR

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Fax: 01625 505 199

Cyprotex Discovery Limited is the world’s largest contract research organisation specialising in preclinical ADME Tox. Established in 1999, Cyprotex works with over 500 partners worldwide to provide the most complete range of ADMET services to research scientists engaged in drug discovery and development. With laboratories in the UK and USA, we provide support for a wide range of experimental and computational ADMET and PK services extending from early drug discovery through to IND submission.

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Dando, Weiss & Colucci Ltd www.dwc-alliance.com/ Tel: 01223 451303 Wellington House, Cambridge CB1 1BH

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One Nucleus Directory 2012

Dando, Weiss & Colucci Limited (DWC) is a management consultancy. We support top scientists in the design, development and implementation of degenerative disease or regenerative medicine focused partnerships.

David Eichler Consultancy Ltd Dr David Eichler eichler@btinternet.com Tel: 01780 480268 07788 923 866 Stamford, Lincolnshire

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More than 30 years experience in non-clinical drug safety, including 22 years with the UK affiliate of F. HoffmannLa Roche and 12 years as an independent consultant. Principally involved at Roche in development of pharmaceuticals for global registration, including preparation for first exposure in man, programme planning and execution of regulatory and investigatory studies, NDA documentation and defence to health authorities worldwide. Major achievements include full (non-clinical safety) development of Vascace, Vascace Plus, Posicor, and Tamiflu, and the early phase development of Invirase. Services include writing research reports and regulatory documentation; independent evaluation of non-clinical dossiers; due diligence; peer review of documentation; design of studies and programmes; attachment to drug development project teams; setting up/ monitoring non-clinical safety studies at CROs; literature reviews.

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David Michalovich Scientific Consulting

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42 Galton Street, London, W10 4QW

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Deliver Plus Ltd Roger Sumner-Rivers sales@deliverplus.co.uk www.deliverplus.co.uk Tel: 0845 5001050 Fax: 0208 7584944 1 Spruce House, Durham Wharf Drive, Brentford Lock, Brentford TW8 8HR

Deliver Plus offers both UK and International express courier delivery. The exclusive One Nucleus tariffs offer savings of up to 70% Deliver Plus provides premium managed logistics services to some of the UK’s largest multinationals. Our healthcare division was established to meet the specialist needs of the biotechnology, pharmaceutical and clinical research industries. Our team of experts understands your specialist needs and can help ensure your clinical trial operates to plan every time. Our managed service offers you a tailored, pro-active service with a dedicated, named account manager assigned to your account; this gives you one point of contact for all your needs and someone with whom you can build a strong working relationship. Through our global network of partners Deliver Plus provides express delivery to over 220 countries worldwide and serves many major destinations such as Europe and the US on a next day guaranteed delivery. We can support cold storage and distribution of life science materials such as critical medications and diagnostic equipment.

diane@delta-consultants.com www.delta-consultants.com Tel: 01480 495047 Fax: 01480 493310

Based in St Ives, Cambs, and covering the UK and Europe, Delta Consultants Scientific and Medical Recruitment offer staffing solutions to the scientific community. Constantly evolving, Delta recruit for customer facing roles in the sales, marketing and service areas while also having in-house expertise to help fill those more technical, administrative or executive roles that require a scientific background. Delta offer over 24 years of operation and over 75 years of industry recruiting experience to ensure that, along with our “Can Do” attitude, we are able to give the best possible chance of success to assignments entrusted to us.

The Old Courthouse, Priory Road, Cambridgeshire, St Ives PE27 5BB

srossiter@dhrinternational.com www.dhrinternational.com Tel: 01727 857755 Dagnall House, Lower Dagnall Street, St Albans AL3 4PA

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DHR International (incorporating Barrett Webb Ltd) Sue Rossiter, Managing Director, Life Sciences Europe

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Delta Consultants Diane Williams

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DHR International is one of the world’s largest global executive search firms, operating through 55 offices around the world. In October 2011 DHR International acquired the European specialist life sciences executive search firm Barrett Webb as part of our strategy to provide truly integrated local, regional and global executive search services within our life sciences clients around the world. We conduct search assignments at the Board, C-level and functional Vice President levels. Our consultants are experienced professionals who are retained by the Fortune 1000 as well as prominent venture firms and early-stage companies. Our Life Science Europe clients are major global companies, private equity backed organisations, start-up companies and NGOs across the biotechnology, pharmaceuticals, medical technology, consumer health and healthcare services sectors. Our consultants have deep industry expertise, backed by a multi-lingual research capability. We manage search assignments across all functional areas including R&D, Marketing, Sales, Business Development, Medical, Technical, Regulatory, Quality, Production, and Business Support areas.

www.onenucleus.com

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Diamond Pharma Services Ltd Paul Cronin pcronin@diamondpharmaservices .com www.diamondpharmaservices. com Tel: 01279 441616 Fax: 01279 418964 No 4 East Wing, Gemini House, Flex Meadow, Harlow, Essex CM19 5TJ

Diamond Pharma Services is a leading technical and scientific consulting group of companies serving the biotechnology and pharmaceutical industry. Our emphasis is on the following areas: • Regulatory Affairs: From Product Concept to Registration and Beyond • Product Development: Nonclinical, CMC and Clinical Aspects • Pharmacovigilance: Clinical trial (Phase I-IV), Post-Marketing and QPPV Services • Compliance: GLP, GMP, GCP and QP Services • Patient Information Leaflet Testing: Over 120 Tested with 100% Positive Agency Feedback Our clients range from virtual start-up companies to the largest multi-national corporations. Our expertise includes products of recombinant DNA and hybridoma technology, nucleotide based products (RNA and DNA), synthetic peptides, chemical entities (innovative and generic), vaccines (therapeutic and prophylactic), blood products and advanced therapy medicinal products (gene therapy products). We have sophisticated and well-equipped office facilities and a state-of-the-art IT system. Our IT system includes a fully validated in-house eCTD system (Extedo) and safety database (ARISg). The company was founded in 2005 by Dr. Maureen Graham, formerly Director of Regulatory Affairs at Amgen. Our specialised team of more than 24 professionals includes those with a broad and varied industry experience and former regulators, offering both breadth and depth of expertise, from which our clients can benefit.

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DiaSorin S.p.A. UK Branch

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www.diasorin.com

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Central Road, Dartford, Kent DA1 5LR

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Tel: 0844 225 9888

With more than 40 years of international experience, the DiaSorin Group develops, produces, and distributes immunoreagent kits for clinical diagnostics. Thanks to its well established expertise, specifically in the immunodiagnostics market, DiaSorin has become “the” in vitro diagnostics specialist. Over the years, by making available to the medical profession tests that can provide optimum guidance in making clinical decisions, DiaSorin has contributed to improving the delivery of health care and reducing its cost.

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Doubletree by Hilton Cambridge Gayle Martin Sales & Marketing Manager gayle.martin@hilton.com www.doubletreecambridge.com

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Tel: 01223 259988 Fax: 01223 316605 Granta Place, Cambridge CB2 1RT

Surrounded by the historic sights of Cambridge the hotel is situated in anenviable position on the banks of the River Cam, boasting some of the best views Cambridge has to offer but only a few minutes’ walk from the centre of the city. With first class facilities for all occasions, business and pleasure, the hotel offers 122 contemporary bedrooms, a stylish Penthouse Suite, Riverside Brasserie, Twist Bar and Lounge, LivingWell health club and seven stylish conference rooms for up to 150 delegates. All bedrooms have been refurbished in a contemporary style with amazing use of light and space. Each offers air-conditioning, a king size bed, Wi-Fi internet, plasma TV, mini bar and laptop safe. Why not host you event in one of seven stylish banqueting and meeting rooms, offering views of the River Cam and equipped with state-of-art audio-visual and communication technology organisers and delegates will have all the facilities they need for a productive and enjoyable event. Cambridge station is just a mile away and both Cambridge Airport and the M11 are only 3 miles from the hotel

Dragon Finance AG James Dimitriou, Vice President james@dragonfinance.ch www.dragonfinance.ch Staldenbachstrasse 9B, Pfaeffikon, Switzerland 8808

Dragon Finance AG, is a Swiss company based near Zurich, specializing in financing and deals in the Pharmaceutical and Alternative Energy sectors. We provide best-practice in corporate transactions through our management and associates. Dragon Finance is an elite group of senior executives with actual deal-making experience in the industry at the corporate HQ level.

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Dundee Cell Products Ltd www.dundeecellproducts.com Tel: 01382 220749 Fax: 01383 226888 3 James Lindsay Place, Dundee Technopole, Dundee DD1 5JJ

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One Nucleus Directory 2012

Dundee Cell Products is an innovative life sciences company that through its Cell Proteomics division develops and commercialises quantitative proteomics-based technologies to help in the development of new and safer medicines quicker through its predictive toxicology technology ToxProfile and TargetId for identifying novel drug targets and determining drug mechanisms of action in the cell. The company through its Cell Products division specialises in developing and commercialising research reagents for cell biology, molecular biology and biochemistry. Our main customers are research scientists based in pharmaceutical and biotechnology companies as well as in academic research institutions. The research services offered to academic and other research institutions include: DNA cloning, gene synthesis, custom monoclonal and polyclonal antibody production, recombinant protein expression and purification and stable cell line development. Key technologies dedicated to assist the development of safer drugs quicker and novel diagnostics included ToxProflle, BioMarkId, PhosProfile and TargetId and are delivered through Dundee Cell Proteomics a division of the company.

The company was founded in 2006 as a spinout from the University of Dundee

Easton Associates EU Ltd www.eastonassociates.com Tel: 0203 008 8440 33 Glasshouse Street, London W1B 5DG

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Easton Associates LLC is a global management consulting firm with offices in New York, London and Beijing.

We provide comprehensive, proprietary planning and evaluation services to senior executives and investors in the healthcare industry. Our engagements span a number of areas including strategy development, market opportunity assessment, corporate and business development, and marketing support to clients throughout the world.

Founded in May 2000, our client list now includes over 200 companies ranging in size from startups to top-five pharma. Easton Associates’ has dedicated staff of over 40 professionals in the U.S., Europe and China, and has a network of former Wilkerson Group colleagues worldwide.

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Eckland Pharmaceutical & Biotechnology Consulting

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www.eckland.org.uk

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Tel: 01923 231263

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17 Berceau Walk, Watford WD17 3BL

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Edwards Wildman Palmer UK LLP Niall McAlister, Partner nmcalister@edwardswildman. com www.edwardswildman.com Tel: 020 7556 4421 Fax: 020 7716 3651 Dashwood, 69 Old Broad Street, London EC2M 1QS

Edwards Wildman is an international law firm of 650 attorneys across three continents that helps clients see their legal challenges from a fresh angle. We have been at the forefront of life sciences for over 30 years with 70 lawyers whose practice is focused on this industry. We work with over 200 life sciences companies, research institutions and investors in biotechnology, medical technology, drug delivery, and pharmaceuticals. In the United Kingdom, we have 20 life sciences lawyers and patent attorneys in London and Southampton who advise on licensing, commercialisation, collaboration and partnering transactions as well as supporting clients with investments, acquisitions, disposals and joint ventures. Most of our UK patent attorneys hold Ph.D.s and have deep technical strength working with subject matter including molecular biology, microbiology, immunology, genetics, cell biology and structural biology.

Tel: 0207 440 9510 Fax: 0207 440 9511 Fairfax House, 15 Fulwood Place, London WC1V 6HU

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EIP www.eip.com

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We are a leading UK firm of patent and trademark attorneys. Our dedicated group, EIP Life, specialises in all aspects of the life sciences, including bio-pharma, medical and laboratory devices, food technologies and industrial biotechnology. We consistently ensure our clients obtain strong and relevant intellectual property which provides a real commercial advantage, our focussed approach ensuring that we fully understand our clients’ business objectives and tailor our advice accordingly. Our services include advising on and obtaining patent and brand protection, oppositions, intellectual property due diligences and freedom to operate analysis

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Eisai www.eisai.co.uk/ Tel: 07791 158 032 Fax: 0845 676 1300

V Eisai is one of the world’s leading research-based pharmaceutical companies. We define our corporate mission as “giving first thought to patients and their families, and to increasing the benefits health care provides,” which we call human health care (hhc). With operations in the U.S., Asia, Europe and it’s domestic home market of Japan, Eisai employs more than 11,000 people worldwide.

Eisai Co Ltd, European Knowledge Centre, Mosquito Way, Hatfield AL10 9SN

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Elkington and Fife LLP www.elkfife.com Thavies Inn house, 3-4 Holborn Cirucus, London EC1N 2HA

Elkington and Fife is a leading firm of patent attorneys and trade mark attorneys with offices conveniently situated in central London and Sevenoaks, Kent. Our partners are acknowledged experts in their fields and have a good understanding of how intellectual property is best used by commercial and industrial organisations, having either worked in industry or worked closely with businesses. We work in all areas of intellectual property, including patents, SPCs, trademarks and designs. We give clear advice, practical solutions and advise with an appreciation of the commercial background rather than from a narrow legal standpoint.

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Elwood Vogt

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Elwood Vogt

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Tel: 01292 281699 07766 663066

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54 Bellevue Crescent, Ayr, Ayrshire KA7 2DR

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elwoodvogt@onetel.com

International general management executive, with broad experience in manufacturing (specifically for FDAregulated products in cGMP environment), business development, marketing, and sales roles, for both technology products and services, in organisations ranging in size from start-up companies to multi-national corporations; Versatile managerial skills with specific strengths in improving under-performing organisations in technology industries, growing SME’s, and building start-ups; Proven ability to fulfil diverse expectations in multi-stakeholder environments, grow income and achieve P&L targets, build distribution networks and lead sales teams to increase revenues, instil strong customer service ethic across all operational areas, create and lead cohesive management teams, improve staff performance at all levels, and provide strategic direction with a clear focus on priority objectives; Specific experience in life sciences, specialty fine chemicals, and micro & nano technology.

Embassy of Switzerland Lutz-Peter Berg lutz-peter.berg@eda.admin.ch www.eda.admin.ch/london Fax: 0207 723 6455 16-18 Montagu Place, London W1H 2BQ

EMBL-EBI www.ebi.ac.uk Tel: 01223 492575 EMBL Outstation, European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton CB10 1SD

The mission of EMBL-EBI is to: provide freely available data and bioinformatics services to all facets of the scientific community in ways that promote scientific progress; contribute to the advancement of biology through basic investigator-driven research in bioinformatics; provide advanced bioinformatics training to scientists at all levels; and help disseminate cutting-edge technologies to industry The research and service activities of EMBL-EBI span the entire spectrum of life science and remain at the cutting edge of the computational sciences.

All our major data resources are the products of international collaborations. We work with other data providers to ensure that our data repositories, and those of our collaborators, are comprehensive and up to date. We also actively participate in international efforts to develop data standards. The EMBL-EBI Industry Programme engages our industrial users with the latest bioinformatics research, service development, standards activities, pre-competitive opportunities and training (www.ebi.ac.uk/industry).

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Emergent BioSolutions Dr Spiros Servos servoss@ebsi.com www.emergentbiosolutions.com Tel: 0118 9443303 Fax: 0118 9443301 Emergent Biosolutions, 540 Eskdale Road, Winnersh Triangle, Wokingham RG41 5TU

One Nucleus Directory 2012

We are a biopharmaceutical company focused on protecting and enhancing life by developing and manufacturing vaccines and antibody therapeutics. Emergent has two operating divisions: Emergent BioDefense Division and Emergent BioSciences Division. Our BioDefense Division is directed to government-sponsored development and procurement of countermeasures against potential agents of bioterror or biowarfare and targets the infectious disease anthrax. Our programs in this division include a strong pipeline of investigational product candidates and one marketed product, BioThrax® (Anthrax Vaccine Adsorbed), the only vaccine approved by the U.S. Food and Drug Administration, or FDA, for the prevention of anthrax disease. Our BioSciences Division targets oncology, including B-cell malignancies chronic lymphocytic leukemia, or CLL, and non-Hodgkin’s lymphoma, or NHL; autoimmune and inflammatory disorders, or AIID, including rheumatoid arthritis, or RA, and systemic lupus erythematosus, or SLE; and other infectious diseases such as tuberculosis, influenza and typhoid.

EOStrat Dr Claire Struthers-Semple css@eostrat.com Tel: 07880 600 362 Fax: 0208 123 8668

A EOStrat offers you access to a highly experienced, multi-disciplinary Virtual Project Team to assist you in developing your new drug. We offer strategic advice in the planning stages, experienced operational resource in the implementation stages and robust issue resolution throughout the lifecycle. After an initial meeting to fully understand the scope, an EOStrat team, to fit your needs, will be compiled. All team members have >20y drug development experience and are flexible and entrepreneurial in their approach. We know what is needed and what is possible in drug development.

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Bartholomew Manor, Argyle RD, Newbury, Berks RG14 6BZ

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Epistem Ltd

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Natasha Tan n.tan@epistem.co.uk www.epistem.co.uk Tel: 0161 606 7378 Fax: 0161 606 7348 Epistem Ltd, 48 Grafton Street, Manchester M13 9XX UK

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Epistem is a biotechnology company with a specialist understanding of epithelial tissue and stem cell analyses, operating three distinct business divisions. The Contract Research Division delivers innovative preclinical research services in the areas of oncology, mucositis, inflammatory bowel disease, wound healing and skincare. Working with over 160 pharmaceutical, biotechnology, and personal care companies worldwide, it offers proprietary assays for target validation, screening, efficacy, and translational biology. The Personalised Medicine Division is committed to facilitating a more tailored approach to patient treatment and care. It applies innovative gene expression technology to discovering novel drug-induced biomarkers to GCLP standard and has recently launched this technology in kit form as RNA-Amp®. It has also developed Genedrive™, a ‘Point of Need’ molecular diagnostic device providing a ‘near patient’ diagnosis in less than 30 minutes using hand held apparatus.

tristan.elliott@eraconsulting.com www.eraconsulting.com Tel: 0207 510 0200 Fax: 020 7510 0218 London Gas Museum, Twelvetrees Crescent, London E3 3JH

The ERA Consulting Group is one of the longest established and most experienced regulatory affairs and product development consulting groups serving the biopharmaceutical industry. Our team of over 35 full-time employees (12 PhDs), are spread through strategically located offices in London, Washington D.C, Germany and Australia. Our strength, quite apart from our regulatory expertise, is our strong scientific focus with a profound understanding of the medicinal product development process and associated regulatory issues. Whilst ERA’s uniqueness lies in our independence (not governed/owned by a CRO/CMO) and that we have supported over 450 medicinal products to date. We assist our clients with activities ranging from agency meetings and advice on regulatory strategy, to the compilation and submission of clinical trial or product registration applications.

Marco.Bocci@ergomed-cro.com www.ergomed-cro.com Castle Park, Cambridge CB3 0AX

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Ergomed Clinical Research Ltd Marco Bocci

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ERA Consulting (UK) Ltd Tristan Elliott, Business Development Manager

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ERGOMED is a European Clinical Development Company, providing consultancy and full clinical trial-related services as well as co-development partnerships which share the risks and rewards of clinical development.

ERGOMED is also well placed to assist emerging and developing biotech and pharma companies by consulting them on strategic clinical development, pre and post-marketing pharmacovigilance and regulatory affaires.

ERGOMED conducts operations throughout Europe and North America with special focus on Central and Eastern European countries and the MENA (Middle East and North Africa) region.

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Eurogentec Ltd Dr Susanna Lovell s.lovell@eurogentec.com www.eurogentec.com Tel: 01794 522417 Fax: 01794 522417 Old Headmasters House, Forest Business Centre, Fawley Road.

Fawley, Southampton SO45 1FJ

V Eurogentec is a leading global supplier of innovative reagents and custom services to scientists in the life science, pharmaceutical and diagnostic markets. Experts in small and large-scale DNA, RNA and peptide synthesis, Eurogentec is an experienced Contract Manufacturing Organization, and is fully ISO 9001 and ISO 13485:2003 certified. It operates two full-service state-of-the-art GMP-compliant manufacturing facilities in Belgium that provide high value custom biologics and a wide range of components for diagnostic and therapeutic applications.

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Europa Bioproducts Ltd www.europa-bioproducts.com 15-17 North Street, Wicken, Ely CB7 5XW

Our main business is the supply of the GLYKO range of glycobiology reagents manufactured by ProZyme Inc. They are used in the characterisation of glycans associated with recombinant proteins. We supply all of the European Biopharmaceutical companies with one or more products. We supply a range of fluorescent proteins and conjugates used in flow cytometry, FRET technology and multiplexing applications. We use our Ecommerce web site to supply these same products to researchers throughout Europe.

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Evotec UK Ltd

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Angela Burt

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info@evotec.com

Tel: 01235 441211

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Fax: 01235 441507

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114 Milton Park, Abingdon OX14 4SA

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Evotec is a drug discovery alliance and development partnership company focused on rapidly progressing innovative product approaches with leading pharmaceutical and biotechnology companies. We operate worldwide providing the highest quality stand-alone and integrated drug discovery solutions, covering all activities from target-to-clinic. The Company has established a unique position by assembling top-class scientific experts and integrating state-of- the-art technologies as well as substantial experience and expertise in key therapeutic areas including neuroscience, pain, metabolic diseases as well as oncology and inflammation.

Evotec has long-term discovery alliances with partners including Boehringer Ingelheim, CHDI, Genentech, Medimmune/Astra Zeneca, Novartis and Ono Pharmaceutical. In addition, the Company has existing development partnerships and product candidates both in clinical and preclinical development. These include partnerships with Boehringer Ingelheim, MedImmune and Andromeda (Teva) in the field of diabetes, and with Roche in the field of Alzheimer’s disease. For additional information please go to www.evotec.com.

Exploristics Ltd www.exploristics.com Tel: 02890 218031 Cromac Square, Belfast BT2 8LA

Exploristics provides innovative analysis solutions to extract information from your clinical data. We support the design and analysis of a broad range of clinical research studies. We have unique expertise in the exploratory analysis and clinical application of high-dimensional data including Biomarkers, Pharmacogenomics, Imaging and Observational data. We collaborate with Pharmaceutical, Biotechnology, Medical Diagnostics and Devices Companies as well as Healthcare Providers.

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Fasken Martineau LLP Charles Waddell

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cwaddell@fasken.com

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Tel: 020 7917 8500

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17 Hanover Square, London W1S 1HU

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Fasken Martineau is one of the world’s leading international commercial law firms, with a global life sciences team comprising over 70 lawyers. Our London based team has more than 125 years collective experience in the sector and one of the most complete life sciences legal offerings amongst any UK firm.

www.fasken.com

Fax: 020 7917 8555

Field Fisher Waterhouse LLP Alison Dennis alison.dennis@ffw.com www.ffw.com Tel: 0207 8614637 Fax: 0207 4880084 35 Vine Street, London EC3N 2AA

One Nucleus Directory 2012

Field Fisher Waterhouse is a UK Top 30 law firm with over 150 partners and over 260 other lawyers offering the full range of legal services. Life sciences clients choose to work with us because we have a substantial team of exceptional lawyers, each with their particular specialism, but who at the same time know the major commercial, legal and regulatory issues affecting this industry sector. They also appreciate that when we say full service, we really can deliver on all counts, be it advising on regulatory matters, corporate and commercial issues, IP licensing and litigation, (including multi-jurisdictional pharmaceutical patent litigation) competition law issues, compliance with data privacy requirements, complex tax arrangements, trade marks, employment and real estate. Through our network of offices in London, Manchester, Brussels, Hamburg , Munich, Düsseldorf and Paris our clients understand that they will get real value from our flexible approach to teamwork and our willingness to shape our structures and way of working to meet their specific needs.

Fire Safety Services

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www.firesafetyservices.co.uk

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Unit 1, Robberds Way, Bowthorpe, Norwich NR5 9JF

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First Ascent Consultancy Ltd

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David Sales, Managing Director

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david.sales@firstascentgroup .com www.firstascentgroup.com Tel: 01223 750807

Clients describe us as the most dynamic and engaged organisation in our field! Our expertise includes: leadership development, team performance development, management development, team building, coaching, talent and graduate development. Our uniquely experienced team of programme directors support you, your team and your organisation with energy, understanding and challenge. We offer mentoring to all our alumni .... for life .... for free. First Ascent service is personal, flexible and responsive. We live your challenges alongside you!

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Fax: 01223 750807 Milton Country Park, Milton, Cambridge CB24 6AZ

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First Sight Media Mike Gilham mikegilham@firstsightmedia. co.uk www.firstsightmedia.co.uk Tel: 0800 0728753 Fax: 01993 832987 Alfred Groves Business Park, Shipton Road, Milton-u-Wychwood OX7 6JP

First Sight Media are dedicated media professionals delivering creative and professional video production, from promotional videos delivered by DVD, to streaming a live event, webinars and conferences, via our servers, to the client’s website. Immersis, our partner company, specialise in organising online events, from inception to delivery, on behalf of our client we will find a suitable venue, organise meals, plan for the live audience and provide live interactive webcasting for e-delegates. This allows the client to concentrate on the content, not the production of the event and reach a global audience for a fraction of the cost of a traditional seminar or conference. For simultaneous viewing of the speaker and presentation slides, live over the web, enquire about iPresenter, perfect for webinars, conferences, new product launches-especially software and training purposes.

Tel: 01279 713320 1 Woodside, Bishop’s Stortford CM23 5RG

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Fisher BioServices www.fisherbioservices.com

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Fisher BioServices – your Critical Material in Safe Hands Part of Thermo Fisher Scientific, Fisher BioServices are experts in clinical trial supply, specialising in clinical services for Phase I to IV trials through to commercial supplies, biorepository services & cold chain logistics. Understanding the special needs involved in clinical studies and in the research and development process, we provide secure, controlled temperature storage, sample collection kit assembly, sample processing and logistics. We are licensed by the HTA, MHRA and HFEA and have ISO9001:2000 accreditation. Our key services include: • Import of supplies into the European Union • Qualified Person services • Secondary packaging • Labelling and assembly • Storage at all temperatures • Worldwide distribution • Returns and reconciliation From our site in the UK, our facilities, systems and procedures are professionally managed and are regularly audited by the Medicines and Healthcare Regulatory Agency (MHRA), our clients, and other regulatory bodies worldwide.

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Fisher Scientific UK www.fisher.co.uk Tel: 01509 231166 Bishop Meadow Road, Loughborough LE11 5RG

V Fisher Scientific is a world-leading supplier of laboratory chemicals, consumables and equipment to the scientific community. Fisher Scientific realises that it’s future lies within the biotechnology sector and indeed, building relationships with networks such as ERBI. Fisher Scientific, therefore, recognises the need to support such important initiatives and take it’s role within these arrangements very seriously. As part of Fisher Scientific’s strategy, it looks to support the members of the ERBI community with specific offers and services designed for scientists and researchers within the biotechnology areas. Examples of these initiatives are: • Dedicated pricing and support on all chemicals, consumables and equipment to all ERBI members. • The new Lab Start-up Program: designed to help scientists give the start that their laboratory deserves. Over 30 different suppliers with over 70 different offers can help a new lab save over £50,000. As a member of the Lab Start-Up scheme, Fisher Scientific can assist with… - Selection, purchasing, and delivery of all product requirements. - Planning and design of a new lab. - Tracking the participants’ Lab Start-Up spend - As a Lab Start-up member, they will automatically be entitled to lots of additional discounts, special offers, dedicated support plus much more. • bioSolutions: A twice-yearly brochure, in collaboration with world leading manufacturers’ designed to give up to date information on new products and promotions. • Specific offers aimed at the biotech sector. Investment in intelligent Customer Relationship Management software enables Fisher Scientific to be very specific in what it promotes to the individual, ensuring that person only receives what is relevant to them.

www.onenucleus.com

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Flexible Lab Solutions www.flexible-lab-solutions.co.uk Tel: 01625 861614 B935a Cornforth Drive, Kent Science Park, Sittingbourne ME9 8PX

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Flight Centre Business Travel

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Charlie Tulip

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www.flightcentre.co.uk/info/ contactus/businesstravel

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Tel: 01223 301940

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charlie.tulip@flightcentre.co.uk

50 Sidney Street, Cambridge, CB2 3HX

FluidX Ltd Emma Ryan emma@fluidx.co.uk www.fluidx.co.uk Tel: 01625 861614 fluidx Ltd, Monks Heath Hall Workshops, Chelford Road, Nether Alderley, Cheshire, SK10 4SY

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Tel: 0845 8730540

www.forecastflow.co.uk

107 New Road, Chatteris PE16 6BT

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At fluidX we offer an ever-developing range of 48, 96, 384 and 1536 plate liquid handling systems complimented by consumables - tips & reagent reservoirs. In the reagent trough portfolio we have a unique chiller trough for keeping reagents cool on the bench and a low cost 100ml polypropylene V bottom reservoir. Also we have a range of benchtop adhesive & heat sealing instruments along with a comprehensive range of seals including ones for optical imaging and sealing compounds in DMSO. We have the widest range of 2D Bar-coded sample storage tubes for sample archiving in a volume range from 200ul - 10ml, the tubes are compatible with Cryo temperature storage. This ensures the users that their samples can always be tracked and then located quickly in the future. We are here to help organise all your samples in your fridges, freezers or biobanks! We have always placed the needs of our customers at the heart of the business so that our products and services continually evolve to meet the requirements of an ever-changing environment. Understanding the balance between the need for reliability and precision combined with budget constraints, fluidX always strive to offer superior products at competitive prices.

Forecast Flow info@forecastflow.co.uk

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Flight Centre Business Travel is a specialist division of Flight Centre Limited providing you with travel management services, focusing on exceptional customer service and best prices in the SME market. Our people guarantee a commitment to personalised service, innovative thinking and genuine cost savings. We also offer specialist expertise and local market knowledge. With our strong alliances with industry leading airlines, hotel and car rental partners, and our global buying power we are able to deliver a cost-effective travel solution for you and your company. We are committed to understanding you the customer and what your unique needs and requirements are.

Forecast Flow helps businesses improve their financial reporting, systems and controls, so they can make proactive day to day business decisions and plan for the future. All businesses should install good financial systems, controls and reporting from day one so that they can understand their financial position at all times. However many businesses ignore installing good financial systems, controls and reporting at their peril and very often end up with inadequate records as they do not understand what they need to run their business. As a result businesses can spend a lot of time and money installing the financial systems, controls and reporting retrospectively to remedy this. The services provided by Forecast Flow can help address this by providing budgets, three year plans, forecasts, management accounts, cash flow forecasts for your reporting needs and help with systems and controls including the installation of accounts packages. business. All companies should put in good financial systems, controls and reporting from day one. The services provided by Forecast Flow can help address this by providing budgets, forecasts, management accounts, cash flow forecasts for your reporting needs and help with systems and controls including the installation of accounts packages. In addition for SMEs Forecast Flow can provide businesses with the in house expertise of a part time Finance Manager.

ForeignExchange Translations, Inc. Steve White, Director of Business Development swhite@fxtrans.com www.fxtrans.com Tel: 01223 366167 Fax: 01223 281276 ForeignExchange Translations, 17 Signet Court, Swanns Road, Cambridge CB5 8LA

One Nucleus Directory 2012

ForeignExchange provide expert translation, multilingual and localisation solutions exclusively to the pharmaceutical, medical device and biotech industries.

We work closely with clients designing and delivering solutions to achieve their linguistic and technical objectives across all stages of the product life cycle to include, legal, clinical, regulatory, quality assurance, manufacturing, labelling, marketing and sales training.

Our standard services include the translation of documentation, labels and IFUâ&#x20AC;&#x2122;s (information for users), the localisation of software, websites and e-learning as well as, back translations, in country reviews, copy editing and desktop publishing. We have experience with EMA submissions.

ForeignExchange is fully certified (EN 15038-2006) and compliant (ISO 9001.2008). We pride ourselves in the quality of our people and processes and contract over 1000 certified native speaking linguists trained and tested in our clientâ&#x20AC;&#x2122;s subject domain.

Visit our website www.fxtrans.com to see more information and access our Audio Conferences and White Papers

Forresters Charlotte Dale cdale@forresters.co.uk www.forresters.co.uk Tel: 020 8889 6622

A At Forresters, we provide clear, sensible and practical advice on intellectual property, including patents, trade marks, designs and copyright, in the UK and across the world. We like to take a collaborative approach with our clients, drawing on their knowledge to ensure that we understand what they want to achieve. We look to deliver our guidance in plain, jargon-free language and are not afraid to recommend a particular course of action, if we think it is right for you. We have a well-established and sizeable life-sciences department, with extensive experience in getting and litigating patents in the UK and Europe.

119–121 Cannon Street, London EC4N 5AT

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GB Innomech Ltd info@innomech.co.uk www.innomech.co.uk Tel: 01353 667394

GB Innomech helps organisations in the pharmaceutical and medical device sectors to manufacture and/or inspect their products through automation. We are experienced with early stage development and with existing products and processes. We are able to offer a number of technologies including: • precision handling and placing; • laser; • precision gluing; • precision welding; • micro dispensing of liquids; • micro dispensing of powders; • multi-axis servo systems; • design of intelligent control systems; • vision and inspection technologies A thorough knowledge of these technologies enables us to automate even the most complex, highly labour intensive manufacturing, inspection or testing processes. Our systems are used by most of the world’s leading pharmaceutical companies, as well as many biotech and contract manufacturers. Our work is undertaken within an ISO 9001:2008 environment and our processes are based upon GxP practice.

GE Healthcare provides transformational medical technologies and services that are shaping a new age of patient care. Our expertise in medical imaging and information technologies, medical diagnostics, patient monitoring systems, performance improvement, drug discovery, and biopharmaceutical manufacturing technologies is helping clinicians around the world re-imagine new ways to predict, diagnose, inform, treat and monitor disease, so patients can live their lives to the fullest. Scientific Asset Services from GE Healthcare offers a comprehensive life cycle asset management solution, going beyond equipment maintenance and designed to help Companies improve productivity while reducing costs. GE Healthcare customized programs can offer solutions for pre-purchase planning and predictive maintenance, as well as managing moves, redeployment and disposal of equipment. Data from the program is used by GE Healthcare to provide business intelligence that helps drive informed decision making. With 15 years of understanding life cycle asset management coupled with a global reach, change management and Lean Six Sigma skills, GE Healthcare delivers a consistent solution where companies need it.

Heron House, Oaks Business Park, Crewe Road, Wythenshawe M23 9HZ

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Gen-Probe Life Sciences Ltd www.gen-probe.com

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GE Healthcare www.gehealthcare.com/uken/

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Gen-Probe is a leader in molecular diagnostics used for diagnosing infectious diseases, screening donated blood, assessing immune response for transfusion, measuring components of the coagulation pathway, helping ensure transplant compatibility, and aiding biomedical research/drug development.

Gen-Probe has nearly three decades of molecular diagnostics expertise, and received the 2004 National Medal of Technology, America’s highest honor for technological innovation, for developing molecular assays and systems that help safeguard the blood supply.

Gen-Probe is headquartered in San Diego and employs approximately 1,300 people.

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Genzyme research.cambridgeuk@genzyme .com www.genzyme.co.uk 12 Rookwood Way, Haverhill, Suffolk CB8 8PB

V Genzyme Haverhill Operations is located on the Cambridgeshire Suffolk border. The site has been a part of Genzyme since 1982 and has grown significantly since that time. In the last 5 years capital investment in the site has exceeded £100M and we employ ~ 300 people at the site in a variety of disciplines.

The site has three distinct functions: as the cold chain supply centre for Genzyme’s small volume therapeutic products; in 2007 we will ship products to 78 countries around the world. We also have the only patent protected continuous API plant in the world. This plant manufactures the active ingredients for a product which is used to treat patients on kidney dialysis. Our third area of expertise is in the process scale up and development of Genzyme’s new synthetic molecules. This team are at the forefront of the implementation of Process Analytical Technologies into our large scale manufacturing plants.

Recognised as a leader within the pharmaceutical and biotechnology industry, we have a dedicated workforce who have the opportunity to learn, develop and achieve, whilst delivering products and services to exacting customer requirements applying best operating practices in safety, quality and efficiency.

www.onenucleus.com

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George James Ltd Jayne McLaughlin, Director jayne.mlaughlin@georgejamesltd .co.uk www.georgejamesltd.co.uk Tel: 07977 192209 Skype: jmclaughlin1313

George James adds value to businesses through its expert services in recruitment and talent management. We have a combined experience of over 150 years in the business areas we support and over 50 years as a service provider. We have a global reach and work extensively throughout Europe and we also network into the US & Canada via our strategic partners. What makes george james unique are our flexible approaches that allows us to employ proactive search strategies at all levels not just senior appointments. Thus we can offer effective solutions to reduce the lost opportunity costs for business critical hires that may have no solution or take many months with less proactive approaches.

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Hotley Bottom Barn, Hotley Bottom Lane, Great Missenden HP16 9PL

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Gill Jennings & Every LLP

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Sarah Hesford

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seh@gje.co.uk www.gje.co.uk Tel: 0207 655 8500 The Broadgate Tower, 20 Primrose Street, London, EC2A 2ES

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Global Regulatory Services Greer Deal greer@globalregulatoryservices .com www.globalregulatoryservices.com Tel: 01353 774000 Fax: 01353 776376 Global House, Painters Lane, Sutton, Ely CB6 2NS

Dr Chris Lawson

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Tel: 0118 935 7285

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Operating at the forefront of technology in the life science industry GRS specialises in new upcoming regulations affecting the life science industry (ranging from food supplements to stem cell therapy). Today’s advances in technology are phenomenal and regulations tend not to keep up with the changes so, in many cases, the regulators consider product registration on a case-by-case basis. GRS has a focus on sectors where regulations are new or still in their infancy so as to help ambitious companies with successful product registration.

Specialist teams have been established who have both scientific skills and regulatory expertise with the ability to communicate effectively with the regulatory bodies so as to achieve the best outcome for clients. Our global understanding adds value to our clients’ product registrations because we are able to incorporate advice and guidance with respect to other markets so as to enhance both their national and worldwide presence.

Glycomix Ltd chrisl@glycomix.co.uk

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Gill Jennings & Every LLP is one of very few specialist IP firms to be top-ranked by all three leading Intellectual Property directories. Although we celebrate our 100th anniversary this year, we are a modern and progressive firm of patent and trade mark attorneys, driven by a business-minded approach to identifying, protecting and managing the IP assets of clients of all sizes. Our Life Sciences group has a wealth of experience in advising UK organisations and entrepreneurs, including universities and spin-outs, start-up companies and SMEs, as well as investors and multi-national companies. We have particular experience in advising UK-based biotechnology companies and have guided an impressive number of these through funding rounds, trade sales and IPOs. Central to this is having a commercial approach to advising clients and providing clear recommendations on IP strategy. We also have some of the most experienced attorneys in Europe handling Oppositions and Appeals at the European Patent Office with an enviable success rate. Our attorneys come from a variety of academic backgrounds and deal with a wide range of chemical and biotech subject matter.

www.glycomix.co.uk Fax: 0118 926 7917 Science and Technology Centre, Earley Gate, Whiteknights Road, Reading RG6 6BZ

Dr Chris Lawson set up Glycomix Ltd in 2007 to provide in depth consultancy and laboratory based research on a range of products and strategies in the carbohydrate sciences. In 1989 he founded Dextra Laboratories Ltd. As joint managing director, he lead the team that developed Dextra into a seriously successful glycobiology company with a catalogue of key research carbohydrates for medical research and a specialist custom synthesis business focussed on sugar chemistry. After completing his Ph.D. in 1969, Chris joined Tate & Lyle as a senior Research Manager and helped bring a number of important projects to market including Xanthan Gum, Sucralose and a number of carbohydrate-related industrial chemicals such as surfactants and emulsifiers.

In 1967, following a BSc in pure chemistry, Chris joined the research team lead by Professor Sir Dai Rees in Edinburgh that demonstrated how polysaccharides form networks and highly organised structures in living tissues which had enormous significance in the food and life science industries. Chris has over 40 publications to date including patents, book chapters and peer reviewed scientific papers.

Gram UK Scott Gibson scgi@gram-bioline.com www.gram-bioline.com Tel: 01322 616900 2 The Technology Centre, London Road, Swanley BR8 7AG

One Nucleus Directory 2012

Gram BioLine refrigeration for scientific & medical applications where temperature control, energy efficiency and green production values are important. • Cabinets range from under bench to large upright double door models • Reliable temperature control between +15?C and -40?C range • Gram MPC 4.6 control unit provides access to: • Audible and visual temperature alarms • High/low temperature log and out of range time/temperature history • Audible and visual door open alarm • Calibration of sensors • Other features include: • Interior and exterior conforms to EN/IEC60079-15 ATEX “sparkfree” standards • Extra sensor (E-sensor) for temperature reference in the storage compartment • Voltage-free contact for external connection to building management system • Smart defrost: minimises length of time and energy used during each defrost cycle • Access port, door lock and 5 year parts and labour warranty Designed for lab needs, built to exceed.

Great Eastern Investment Forum (GEIF)

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www.geif.co.uk

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Ravenscroft House, 61 Regent Street, Cambridge CB2 1AB

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Greatspur Clinical Development Ltd

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enquiries@greatspur.co.uk

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www.greatspur.co.uk Tel: 01953 714942 42 Kenninghall Road, East Harling, Norwich NR16 2QD

Greatspur Clinical Development Ltd is a small, privately owned Ltd Company providing a range of advice and support services to pharmaceutical and biotechnology companies on the planning, preparation and conduct of clinical trials. Working with clients from the late pre-clinical stage to develop and manage Phase I trials, Greatspur can provide product development and clinical trials support throughout the development process. The company can offer in-depth knowledge and experience of the clinical research environment and a network of regulatory and other industry associates. Services include project management, medical writing and quality management services, including quality systems and procedures development and support for regulatory inspections. Our aim is to deliver a professional service tailored to our clientsâ&#x20AC;&#x2122; needs, coupled with a commitment to high quality and timely delivery.

www.gf.associates.co.uk Tel: 01353 645590 Fax: 01353 645599 30 St Thomas Place, Cambridgeshire Business Park, Ely CB7 4EX

GFA is an expert regulatory, clinical research and GCP QA contract company, providing practical advice and support to the biopharma industry to move products from early concept, into the clinic and on to Marketing Authorisation. Our range of services includes: Agency meetings and briefing document preparation, clinical trial approvals, Orphan Drug applications, MAA, Clinical trial management and monitoring, GCP QA audits and SOP writing, medical writing, US Resident Agent services, EEA Legal Representative services and Pharmacovigilance.

GFA has an excellent understanding of the global regulatory arena, and supports in particular European companies seeking to expand development to the US but also US companies coming to Europe. What sets us apart is our combination of both clinical and regulatory expertise within the one consultancy group, allowing a comprehensive approach to product development encompassing the needs of regulatory requirements and the clinical research process.

Clinical Waste Division, Star Works, Star Lane, Knowl Hill RG10 9XY

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Grundon Waste Management Ltd www.grundon.com

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Gregory Fryer Associates Ltd info@gf-associates.co.uk

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Established in 1929, we are proud to be the largest family run waste management company in the UK. We have developed our service over the years to specialise in establishments that require a high level of expertise and technical knowledge. We have established a large customer base of scientific research companies providing consultancy, collection and subsequent high temperature incineration of their hazardous wastes. At our facility near Heathrow Airport. We employ a variety of collectin vehicles operated by fully trained drivers and provide documentation to ensure compliance with all relevant legislation and guidelines.

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Hannah-Reed www.hannahreed.co.uk Tel: 01223 882000 Telford House, Fulbourn, Cambridge CB21 5HB

V Project Management consultants focussed on the design and procurement of research facilities. Working on behalf of the end user, we have acted on behalf of the majority of the major occupiers locally. Clients include Acambis, Amedis, Astex, Biofocus, CAT, CCD, Celltech, Cellzome, Domantis, Intercytex, Ionix, Lorantis, MedImmune, Medivir, Millennium, Paradigm, Peptide, Pfizer, PPD, Ribotargets, Vernalis and others. Also teaching and research facilities for the University of Cambridge and University of Nottingham. Total portfolio of developments exceeds 105,000sqm of new build and refurbishments. Services range from site selection and negotiation of agreements, with, and financial contributions from, landlords - through to design management and fit-out procurement. We have established an extensive database of design solutions, benchmark costs and development programmes and can give an early indication as to what can be achieved, at what cost and by when.

www.onenucleus.com

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Harrison Goddard Foote Richard Williams – Partner rwilliams@hgf.com www.hgf.com Tel: 0207 440 8900 Fax: 0207 440 8901 40-43 Chancery lane, London WC2A 1JA

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Harten Group Ltd

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Dr Vernon Harten-Ash

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www.hartengroup.co.uk

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enquiries@hartengroup.co.uk

7 Pioneer Court, Explorer House, Vision Park, Chivers Way, Histon, Cambridge CB4 9PT

HGF is a leading UK partnership with offices across the UK. Our continuing growth against the backdrop of challenging global economic conditions reflects the depth and accessibility of our expertise and the overall strength of our offering to clients, whether newly welcomed or long standing. We are Legal500, Chambers and MIP recommended year on year, and now the third largest filer of PCT applications in the UK. Our patent and trademark attorneys and HGFLaw solicitors are each personable and specialist in their particular field. We work collectively in business focussed teams covering the full spectrum of technical disciplines: life sciences, pharma, chemistry, mechanics, electronics, trademarks and law. We have one of the largest - and we would say the best - life sciences/pharma practices in the UK. We give prompt, coordinated, comprehensive and local service in the entire IP space; from procurement to enforcement and litigation; from due diligence to global strategic advice.

Harten Group is one of Europe’s leading providers of consultancy, interim management and executive search for the pharmaceutical and biotech industries. With over 2000 highly qualified specialists the company, which has been established for 16 years, delivers flexible resourcing solutions to meet specific needs - mostly in the UK but also in Europe. This bank of expertise can be harnessed in many different ways, from the recruitment of a single interim manager on a contract basis, finding a permanent employee through executive search for a ‘difficult to find role’ or fielding a team of consultants to address a more complex challenge.

Harts Office Supplies Sharon Hayes sharon@harts1836.co.uk www.hartsdirect.co.uk Tel: 01799 510128 Hart House, Shirehill Industrial Estate, Shire Hill, Saffron Walden CB11 3AQ

Harts was established in 1836 and is a leading UK dealer providing a ‘Single Office Solution’ for all One Nucleus Members . An excellent reputation has been built up within One Nucleus based on competitive pricing, excellent, fast and professional customer service. Distribution is locally based, with a national capacity supported by a stock holding in excess of GBP5M available for next day delivery. Additional Value Added Services include:Shopping Service for catering & cleaning requirements. • Try before you buy’ on Office Seating. • Ergonomic Surveys.• Office Refurbishments/ Project Management Space Planning (CAD) • Leasing solutions spreading capital expenditure. • Used Toner Collections. • Print Audits helping to reduce expenditure. • Print Management. •In-house Design Print Service. • Business gifts - any product can be sourced • Audio Visual Products and Installations • PAT Testing • PPE Equipment (Personal Protection Equipment).

Benefits: *Service Level Agreement *Weekly and Monthly KPI’s *Quarterly reviews *Competitive pricing for One Nucleus Members *Solutions to help reduce expenditure *Stock replenishment (cupboards) *Single Sourcing of non-core office products & Specials *Single point of contact *Web ordering systems & Online catalogues *Next day delivery *No quibble returns *Management information *Tailored Invoicing *Credit procurement cards accepted *Environmental awareness *One Nucleus Office Supplies Discount structure - Core Contract Price List for office supplies – (with up to 80% off RRP) *Unique Contract Price List on the most commonly used products *Discounts with up to 70% off RRP prices *Additional discounts off RRP on ‘Value for money Q Brand’ *Own brand Toners - 100% guaranteed - up to 10% additional page life - significant comparable savings.

Haverhill Research Park www.haverhillresearchpark.com Tel: 0207 493 6774

Bespoke 450,000 sq ft of labaratory, office,technology and supporting accommodation for a wide spectrum of companies from start ups to global players within a very attractive landscaped environment.Will include Innovation Centre, hotel, Pub and creche

22 Grosvenor Square, London W1K 6DT

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Health Protection Agency Business Development Dept. business@hpa.org.uk www.hpa.org.uk Tel: 01980 612223 Fax: 01980 612241 Porton Down, Salisbury SP4 0JG

One Nucleus Directory 2012

The UK’s Health Protection Agency provides solutions to infectious diseases and environmental hazards in partnership with industry, governments and universities. With expertise in developing diagnostics, vaccines and other countermeasures, allied with our capabilities in process development, scale-up and GMP manufacture, the HPA is unique in being able to undertake translational research and turn ideas into new healthcare interventions and products. By combining our experience in emergency preparedness and planning with specialist testing, research capabilities and internationally recognised EQA schemes the HPA is one of the world’s leading organisations dedicated to combating world wide health threats.

Helix Recruitment Ltd Dick Donovan info@helixrecruitment.co.uk www.helixrecruitment.co.uk Tel: 01323 445464 3 Town House Garden, Market Street, Hailsham BN27 2AE

A Specialising in customer facing roles in science and healthcare markets, Helix has created a service aimed at PEOPLE, believing that recruitment only works well if viewed as a partnership between agency and candidate as well as agency and client company. Recruitment is NOT a commodity business! Success has been built through partnership and delivery of effective solutions tailored to clients’ needs and with uncompromising standards of integrity and service. For CANDIDATES : Recruiters have experience of your industry and understand the realities and complexities of the varied roles for which we recruit. We work hard to help achieve your career goals. All CVs & personal details are kept strictly confidential as required by Data Protection Act. For CLIENTS : Our aim is to bring professional, committed and talented people to your business. Whilst the majority of our activity is contingency recruitment, we undertake specific assignments for “new team” or more specialist roles.

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Heptares Therapeutics

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www.heptares.com

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Biopark, Broadwater Road, Welwyn Garden City AL7 3AX

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Herring Partners maurice.herring@herringpartners.com www.herringpartners.com Tel: 01223 300924

Herring Partners is a senior level executive search consultancy working with a select group of clients globally in the Life Sciences Industry. We provide an exclusive, tailored service with superior quality that ensures effective assignment delivery. Our clients are focused in the pharmaceutical, biotechnology, biopharmaceutical, diagnostics, research tools, medical technologies and devices sectors.

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We operate at “C” level, SVP, VP, Senior Director, Director and Head levels. We also provide Non-Executives for Boards of emerging and established businesses.

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Our experience enables us to search in most functional job disciplines with particular strengths in Business Development, Sales & Marketing, Operations, Quality, Research, Development, Medical Affairs, Regulatory Affairs, Human Resources and Finance.

Our heritage is based on extensive broad industry experience plus more than 22 years in Life Science executive search. Maurice Herring was the co-founder and MD of PiR Group.

The partnering approach adopted by Herring Partners allows us to work closely with tried and tested associates and researchers around the world, experts in their geographic and functional disciplines. Clients receive only the highest level service from our expert team to ensure a personalised and results focused approach, when and where it is needed.

HighQ Jacob Mathew, Knowledge Management Consultant jacob.mathew@highqsolutions .com www.highqsolutions.com Tel: 020 7220 5340 7th floor, 19-21 Great Tower Street, London EC3R 5AR

HighQ is the leader in cloud based enterprise collaboration, data rooms and secure document exchange allowing companies of all sizes to collaborate with people inside and outside of their business. HighQ offers the highest degree of security and reliability combined with unparalleled speed, ease of use and functionality which is supported by Windows PC and Mac platforms. Global clients from various industries such as Financial Services, Legal, Biopharmaceutical, Government departments, Banks have been using HighQ technology in a variety of business transaction scenarios such as due diligence for mergers and acquisitions, loan syndication, biotech licensing, intellectual property (IP) protection, project collaboration, secure extranets, knowledge management portal, Boardroom communications and secure document exchange with external vendors, distributors, regulatory agencies and strategic partners.

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HLBBshaw

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Dr Marc Wilkinson Senior Attorney

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marc.wilkinson@hlbbshaw.com www.hlbbshaw.com

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Merlin House, Falconry Court, Bakers Lane, Epping CM16 5DQ

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HMA Digital Marketing Dr Ceri Batchelder ceri@hma.co.uk www.hma.co.uk Tel: 01226 209 450 Fax: 01226 209 451

Specialising in life sciences and healthcare, HMA is a leading digital communications agency that’s been at the forefront of website design and development since 1995. We create digital and social media solutions for a wide range of healthcare clients, from SMEs to global companies in the medical technology and biopharmaceutical fields. Clients include 3M Healthcare, Bionow, Kent Science Park, MEPC (owner of Granta and Milton Parks), Norwich Research Park, Novozymes Biopharma, Smith & Nephew, UK Trade & Investment and the Universities of Sheffield and York. Our capabilities include online brand strategy, website design and development, 3D animation and illustration, design and creativity, email marketing, smartphone applications, search engine optimisation, social media and video production.

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The Coach House, 51 Sackville Street, Barnsley S70 2BZ

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ICON Development Solutions

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www.iconplc.com

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Fax: 0161 227 6565

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Tel: 0161 232 2714

Parkway One, Parkway Business Centre, 300 Princess Road, Manchester M14 7QU

With expertise in early phase clinical research (including first in human, dose escalation, PK/PD, multiple dose, food effect, drug interaction studies, dosage regimen assessments, bioavailability, bioequivalence, diabetic clamp studies, QTc studies, Phase I patient studies, special population studies, special population studies, proof of concept studies), Pharmacodynamic Models, bioanalysis (LC-MS/MS, Immunoassay and Biomarker analysis), PK/PD modeling & simulation and the full range of supporting services, we incorporate scientific excellence and product development strategy in all that we do. Our multi-disciplinary experts have the experience to address the most demanding drug development challenges with an unyielding focus on completing projects on time, on budget and with the quality that will withstand the most vigorous scrutiny.

Illingworth Research Ltd www.illingworthresearch.com Suite 5, Silk House, Park Green, Macclesfield SK11

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Immodulon Therapeutics Ilda Guimarey

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www.immodulon.com

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Fax: 0203 219 3574

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Tel: 0203 219 3568

22 Devonshire Place, B2 London W1G 6JA

Immodulon is interested in mycobacterial-based immunotherapies aimed at restoring appropriate immunoregulatory responses in conditions characterised by immune dysregulation. These products have potential in a wide range of indications and are expected to complement established and emerging clinical therapies. We are presently concentrating on developing immunotherapeutic options as adjunctive therapy for certain cancers with the aim of extending survival and enhancing quality of life. Through collaborations we are also supporting mycobacterial immunotherapy for the prevention and treatment of tuberculosis, following encouraging clinical data.

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Imperial Innovations Kathryn Owen Kathryn.owen@imperial innovations.co.uk www.imperialinnovations.co.uk Tel: 020 7594 6584

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52 Princes Gate.

Exhibition Road, London SW7 2PG

One Nucleus Directory 2012

Imperial Innovations creates, builds and invests in pioneering technologies addressing global problems in healthcare, energy, engineering and the environment. Imperial Innovations builds and invests in companies based on technologies from or associated with four universities: Imperial College London, Cambridge University, Oxford University and University College London and supports scientist-entrepreneurs in the commercialisation of their ideas by: • leading the formation of new companies and providing facilities in the early stages • providing significant investment and encouraging co-investment to accelerate development • providing operational expertise • recruiting high-calibre management teams

Indiana Economic Development Corporation UK

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www.iedc.co.uk

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Tel: 020 7352 1672 114 The Plaza, 535 Kingâ&#x20AC;&#x2122;s Road, London SW10 0SZ

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Integrated Medicines Ltd

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Dr Eddie Blair

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eddie.blair@integratedmedicines .co.uk www.integratedmedicines.co.uk Tel: 01954 718122

Integrated Medicines (IML) aims to introduce companion diagnostics into the drug development and commercialization pathways at appropriate time points. It does this by providing both services and products of interest to the healthcare sector including product value assessments, relationship brokering and tunable magnetic proteins (see integratedmagnetics.co.uk). Since inception in 2003, IML has worked with large and small companies, academics and applied research centres, as well as providing due diligence support to private investors and public sector organizations. Please visit our website to find out more, download information and join our newsletter mailing list.

Topfield House, Ermine Street, Caxton CB3 8PQ

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International Science Writer Dr Sue Pearson, Director sue.pearson@international sciencewriter.com www.internationalsciencewriter .com Tel: 01462 635327 07906118977 Fax: 01462 635327 P O Box 170, Hitchin, Hertfordshire SG5 3GD

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At International Science Writer (ISW), we help life science, biotechnology and pharmaceutical companies to build their profile and generate commercial leads by providing timely, well-written copy for any form of scientific PR and marketing communication. We can deliver professional copy for your press releases, articles, brochures, newsletters, advertising and annual reports.

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InterPharm Investments Ltd

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www.interpharminvestments. com

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Tel: 01483 237153 Fax: 020 7259 8480

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156-158 Buckingham Palace Road, London SW1W 9TR

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IP Asset

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www.ipasset.com

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4th Floor, 33 Cavendish Square, London W1G 0PW

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IP Pragmatics Ltd Elaine Eggington info@ip-pragmatics.com www.ip-pragmatics.com Tel: 0203 176 0580

IP Pragmatics works with growing biotech companies and universities to create and realise value from their life science intellectual property, through provision of cost effective and commercially relevant business development, IP valuation and patent management services. We help our clients to identify, manage and create value from a broad range of intellectual property (IP) assets. Our successes include creating value through licensing, spin-out company creation and enhancing commercial service offerings for clients in the UK and overseas. Typical clients include companies both small and large, universities, research institutes and investors.

1 Quality Court, Chancery Lane, London WC2A 1HR

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ISIS Pharma Consulting Ltd

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Indira Walker

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www.isispharmaconsulting.com/

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indira@isispharmaconsulting.com Tel: 01234 834795 07941 259781 Suit F6 Bedford i-Lab, Priory Business Park, Stannard Way, Bedford MK44 3RZ

Ithaka Life Sciences Ltd Paul Rodgers info@ithaka.co.uk www.ithaka.co.uk Tel: 01223 703146 St John’s Innovation Centre, Cowley Road, Cambridge CB4 0WS

www.jakemp.com 14 South Square, Grays Inn, London WC1R 5JJ

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James Cowper LLP www.jamescowper.co.uk Tel: 01865 200500 Fax: 01865 200501 Willow Court, 7 West Way, Botley OX2 0JB

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Ithaka is a leading advisory and interim management business specialising in commercialisation of life science technologies. Our clients include companies, investors, public sector bodies, Universities and other research institutions. Our services include: • Technology, IP, commercial and market reviews, including due diligence; • Development and implementation of commercialisation strategies and business plans; • Start-up company creation and sourcing funding; • Provision of interim directors or senior management for growing companies.

In addition to wide ranging business experience we have in-depth expertise in the following technology sectors: • Therapeutic proteins and antibodies; • Biomarkers and diagnostics; • Life science research tools; • Regenerative medicine and medical devices; • Drug discovery.

JA Kemp & Co

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Isis Pharma Consulting Limited offers a unique combination of Quality Assurance and Regulatory Affairs expertise, supported by considerable senior management experience. We offer interim management and bespoke consultancy services. The company is headed by Indira Walker who is ably assisted by a team of associates. All our associates have a wide range of specialisms including Interim Management, Auditing, Quality and Regulatory Affairs. All team members are expert in developing compliant operationally effective and commercially sensible solutions for your business. We believe we offer outstanding customer service, immersing ourselves in the client organisation with dedication and enthusiasm.

One Nucleus Directory 2012

J A Kemp & Co is a leading UK Patent and Trade Mark Attorney firm with a long-established reputation for high quality work. The Legal 500 described J A Kemp & Co as an ‘excellent’ firm with many world-class organisations amongst its patent and trade mark clients. Chambers & Partners identified the firm as ‘one of the more established and well respected players in the sector’, while Managing Intellectual Property commented that ‘J A Kemp & Co boasts one of the UK’s most highly qualified collections of attorneys’

Kelly Scientific Resources ksr@kellyservices.co.uk www.kellyscientific.co.uk Tel: 020 3040 1912

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Kelly Scientific Resources is the largest and most trusted scientific staffing company in the world. We have offices across the UK with highly skilled and experienced consultants who all have a strong background in science. A key to our success is our commitment to the scientific sector. We not only consider ourselves a supplier, but as an active part of the scientific community.

Apple Market House, 17 Union Street, Kingston-upon-Thames KT11RR UK

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Kilburn & Strode LLP www.kstrode.co.uk Tel: 0207 539 4200 20 Red Lion Street, London WC1R 4PJ

Kilburn & Strode LLP is a leading, top-tier London partnership of European Patent Attorneys, Chartered Patent Attorneys and Trade Mark Attorneys, dealing with all aspects of Intellectual Property, including patents, trade marks, domain names, design, copyright, passing-off and confidential information. The acquisition, enforcement and licensing of worldwide IP rights on behalf of our clients forms a core part of the business. It is consistently rated in the top tier in all independent surveys and the qualified patent and trade mark attorneys and litigators are made up of eighteen partners, seventeen associates and two consultants, each of whom specialise in dedicated fields of interest ranging from chemistry, through life sciences, engineering and IT & electronics.

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King’s College London Business Ltd www.kcl.ac.uk/innovation/ business/contactus/index.aspx Tel: 020 7848 8233 Fax: 07848 3193 8th Floor Capital House, 42 Weston Street, London SE1 3QD

King’s Business is a wholly owned subsidiary of King’s College London, responsible for driving innovation within one of the UK’s leading research universities. Our mission is to optimise the impact of research at King’s College London through the development of new opportunities and partnerships and to create value for the College in its externally-facing activities. The team supports the development of relationships with a broad range of external partners, including public sector, charities, cultural organisations, industry and SMEs across the whole range of our academic disciplines. This occurs via research collaborations, consultancy, executive education, the protection and licensing of IPR and the creation of new ventures.

simon@kisscom.co.uk www.kisscom.co.uk www.kissfuture.co.uk www.kisspr.co.uk

KISS Communications is the integrated agency dedicated to keeping it simple. Our experienced team energise brands that aspire to be number one in their category, gain distribution and increase sales around the world. We provide advertising, design, branding, digital, exhibitions and public relations services prepared against strategic plans with concise success measurement. The KISS guiding principles are to have a lack of unnecessary complexity in everything we do whilst delivering maximum effect with minimum means.

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KWS BioTest Ltd

www.kwsbiotest.co.uk

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Church House, Kneesworth Street, Royston SG8 5AB

William.parish@kwsbiotest. co.uk

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Tel: 01223 911123

William Parish

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KISS Communications Simon Fryer

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V KWS BioTest is an established contract research organisation that brings together internationally renowned scientific expertise in a commercially managed environment for the testing of prophylactic and therapeutic agents as treatments for human disease. We work closely with clients to to develop a truly bespoke and individual program. KWS BioTest offers a range of in vitro and in vivo preclinical services in the core areas of inflammation, infection, autoimmunity, allergy, CNS and pain.

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Tel: 01795 599544

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975 Cornforth Drive, Kent Science Park, Sittingbourne ME9 8PX

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La Playa Ltd www.laplayainsurance.com Tel: 01223 200650 The Stables, Impington, Manor Farm, Milton Road, Cambridge CB24 9NG

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Labute Ltd

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Dave Jones

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www.labute.co.uk

dave@labute.co.uk

Headquartered a short distance from Cambridge Science Park, and also with offices in London, La Playa provides expert, independent insurance and risk management advice for life science enterprises of all sizes.

Our clients work in some of the most innovative, game-changing sectors in the UK, including drug/vaccine development, medical devices & healthcare sciences, bioinformatics, electronics and nanotechnology - so we know a thing or two about unconventional risk. And how to manage it. We offer FREE Enterprise Risk Planning for all ERBI members, helping start-ups to become investor-ready and helping more established firms to benchmark their insurance portfolios against current ‘best practice’. Advice & consultancy encompasses: • Asset Protection & cover for R&D activity • Consequential Losses • Intellectual Property • Employers’, Public & Product Liability • Professional Negligence • Directors & Officers Liability • Clinical Trials Liability • Environmental Liability • Crisis Management & Disaster Recovery • Product Contamination & Recall

Founded in 1978 Labute is Cambridge’s oldest commercial printing company. Incorporating a wide range of both modern and traditional printing technologies our aim is to help our customers achieve their marketing objectives by communicating with whichever printing discipline is most effective.

Tel: 01223 428590

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The Cambridge Printing Park, Milton, Cambridge CB24 6AZ

LA-design www.LA-design.co.uk Tel: 01442 862631 Fax: 01442 874354 105 High Street, Berkhamsted, Herts HP4 2DG

New clients come to LA for many reasons but it’s our business focused approach and award winning innovative solutions that result in unprecedented customer retention and highly effective long term working collaborations.

LA is one of the UK’s most respected and successful industrial design and product development consultancies.

Having won nine DBA Design Effectiveness Awards we continue to develop our services in line with rapidly changing requirements and deliver brand led solutions that connect technology and business with people – this is a winning combination.

Leadership Skills Training Ltd info@presentwithimpact.co.uk www.presentwithimpact.co.uk Ovation House, 22a Ridgmont Road, St. Albans AL1 3AF

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Leads to Development Dr Jonathan Kearsey jkearsey@leadstodevelopment .com www.Leadstodevelopment.com Tel: 0207 183 6415 Fax: +33 182 2853 79 Paris Biotech Sante, 24 rue du Faubourg Saint-Jaques 75014 Paris France

One Nucleus Directory 2012

LEADS TO DEVELOPMENT (L2D) manages the development of its clients’ novel therapeutics, from in vivo proof of concept through to phase I clinical trials, using scientific, project management and business expertise. Our services allow our clients to reach clinical milestones rapidly and cost effectively, without building headcount and infrastructure. We assess project potential, design development strategies and deliver effective project advancement in order to minimise risk and increase project value. Our experience of the biotechnology sector also allows us to offer a range of business services and strategic advice (including due diligence) to investors and drug developers.

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Leyton Suzie Dennis sdennis@leyton.com

Leyton is a consulting firm with a unique goal â&#x20AC;&#x201C; to quickly improve the financial performance of its clients without impacting on their core business. In the UK, our specific expertise is in the optimisation of R&D tax credits and R&D grants.

www.leyton.com Tel: 020 3051 2183 Landmark House, Hammersmith Bridge Road, London W6 9DP

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Managing Resources Ltd

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Alan Williams

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www.managingresources.com

info@managingresources.com

Tel: 01223 566158

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18 Topcliffe Way, Cambridge CB1 8SH

Mandeville Technology Ltd Andrew Muncey andrew-muncey@hotmail.com www.mandevilletechnology .co.uk Tel: 01799 501667 07989 420 696

Marks and Clerk Tim Andrews

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Tel: 01223 345520

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Fax: 01223 365560

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Mandeville Technology Limited provides flexible Chief Financial Officer or Finance Director services to healthcare and technology companies. Services in the following areas are available: Accounting, including: Audit preparation Financial reporting Management accounts Company secretarial Corporate finance, including: Deal structuring Disposals Equity funding Financial modelling Mergers and acquisition Valuations Venture debt Corporate and financial strategy, including: Budgeting and forecasting Business and financial advice Corporate restructuring Employee incentive schemes, including: EMI share options Employee benefit trusts Share purchase schemes Non-executive director Taxation, including: EIS R&D tax credits VAT

26 Borough Lane, Saffron Walden CB11 4AG

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Many of our present and future clients are based in countries like USA, Canada, Australia and New Zealand.

They recognise the European potential for their products; they require our help in understanding the market opportunity, appreciating the varied healthcare structures in different countries, determining the best entry strategy and finding the right partners, possibly including M&A. We provide support in regulatory affairs, finding finance, addressing legal issues and recruiting permanent staff recommending specialists that we work with regularly.

Marks & Clerk is one of the most highly regarded intellectual property firms in the UK. Our patent and trade mark attorneys and solicitors offer clients single point access to a comprehensive range of IP services across a full range of sectors - with notable experience in life sciences. Services include strategic IP and practical advice on patent and brand protection and portfolio management, licensing and other commercial contracts, enforcement, due diligence and litigation. Working closely with clients to understand their specific business requirements, we produce commercially effective work at a competitive price. We have a network of offices in the UK (10 locations), in Europe, Asia and North America providing clients with an integrated local and global service.

62-68 Hills Road, Cambridge CB2 1LA

Mathys & Squire LLP Martin MacLean mrmaclean@mathys-squire.com www.mathys-squire.com Tel: 020 7830 0000 Fax: 020 7830 0001 120 Holborn, London EC1N 2SQ

One Nucleus Directory 2012

Mathys & Squire has over 100 years of experience in providing Intellectual Property services to UK industry. Our attorneys work across a number of technical disciplines, including biotechnology, pharmacology, healthcare & medical devices, and chemistry. We have a global track record in securing valuable Intellectual Property rights for universities, government, start-ups and spin-out companies. Our attorneys also specialize in freedom-to-operate and due diligence activities, and we are particularly proud of our extremely high success rate in both defending and challenging patents before the European Patent Office. Most importantly, we develop IP strategies that align with our clientsâ&#x20AC;&#x2122; commercial plans.

Maxwell Safety & Health Ltd Chris Maxwell info@maxwellsafety.com www.maxwellsafety.com St John’s Innovation Centre, Cowley Rd, Cambridge CB4 0WS

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Maxwell Safety was formed in 2005 with the aim of providing practical, cost effective health and safety solutions for small and medium enterprises. We have particular expertise within the biotechnology, pharmaceutical and ‘hi-technology’ sectors. The company has very close links with One Nucleas providing health and safety training for its members, including Biological Safety Officer and Laboratory Safety training. Our H&S consultants are Chartered Health and Safety Practitioners, with extensive experience in delivering pragmatic health and safety solutions and dynamic training. We are committed to supporting managers responsible for health and safety to comply with legislation and to adopt a sensible approach to health and safety that is a benefit to the business, not a hindrance.

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Medical Research Council

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Kevin Pearson

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techtran@mrc-centre.cam.ac.uk www.mrc.ac.uk Tel: 01223 248011 Fax: 01223 252957 Hills Road, Cambridge CB2 0QH

For almost 100 years the Medical Research Council has improved the health of people in the UK and around the world by supporting the highest quality science. The research it funds plays a central role in maintaining the UK’s world-leading medical research sector. The MRC invests in world-class scientists, trains the research leaders of tomorrow and sustains a flourishing environment for internationally recognised research. It has produced 29 Nobel Prize winners. The MRC invests over £60 million in Cambridge annually, providing around 700 jobs at its seven Cambridge research establishments: the MRC Laboratory of Molecular Biology, the MRC Biostatistics Unit, the MRC Cancer Cell Unit, the MRC Epidemiology Unit, the MRC Mitochondrial Biology Unit, MRC Human Nutrition Research and the MRC Cognition and Brain Sciences Unit. The MRC’s expertise in these important areas offers great opportunity for fruitful interactions with industry and academia alike.

nigeledwards@medicon.co.uk www.medicon.co.uk Tel: 020 85630368 07768 104974 Fax: 0870 7052028

Medicon is a strategic transactions practise serving the Pharmaceutical, Biotech, MedTech and Venture Capital industries on a consultancy or interim basis. We typically work on commercialisation strategy, and execution via Alliance and IP License negotiations, M&A, and distribution deals. Projects have included leading negotiation of Alliances and Licensing deals, M&A, Distribution planning and execution, Business Plans, International Commercial strategy, Intellectual Property strategy and IP due diligence, International Marketing campaigns, Competitive analysis, valuation and market forecasting. Over 25 strategic transactions with Abbott, J&J, Boston Scientific, Dideco, WJ, NOF, Rita, Angiodynamics, Tripos, and R&D agreements with companies, Academia, and Tech Transfer organisations

5 St Hilda’s Rd, London SW13 9JE

tommi.pisto@medisapiens.com www.medisapiens.com Tel: 35 8503 631 848

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MediSapiens Ltd Tommi Pisto

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Medicon Strategic Development Ltd Nigel Edwards

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MediSapiens is a bioinformatics company developing inspiring web applications for genomics researchers, pharmaceutical industry and personalized medicine. MediSapiens has unique know-how in developing software solutions for integration of both molecular and clinical data from preclinical models to interpreting comprehensive molecular profiles of individual cancer patients in clinical settings. Based on the world’s largest unified gene expression database, MediSapiens platform extends into highly tailored solutions to meet the exact needs of various demanding research environments.

Tukholmankatu 8 A, Helsinki 00290 Finland

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Merck & Co Inc licensing_europe@merck.com www.msd-uk.com Tel: 01992 452840 Hertford Road, Hoddesdon EN11 9BU

V Merck Sharp & Dohme Ltd (MSD) is the European subsidiary of Merck & Co., Inc., of Whitehouse Station, New Jersey, USA, a leading research-based pharmaceutical company that discovers, develops, manufactures and markets a wide range of innovative pharmaceutical products to improve human health. Today’s MSD is a global healthcare leader who is working to help the world be well. Through our medicines, vaccines, biologic therapies, and consumer and animal products, we collaborate with human and animal health professionals across the UK and in more than 140 countries to deliver innovative health solutions. A comprehensive list of our interests is available at www.merck.com/licensing and includes: atherosclerosis and cardiovascular disease, stroke, diabetes and obesity, asthma and COPD, pain, oncology, antibiotics, antifungals, antivirals (HCV and HIV), novel vaccines, Alzheimer’s disease, neurodegeneration, schizophrenia, ophthalmology, osteoporosis, and women’s health. For Phase III-ready candidates and beyond, Merck is interested in any therapeutic area. We are also seeking to integrate key product enablers (e.g., biomarkers, diagnostics, devices, and information) into the development of our products.

www.onenucleus.com

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Merck Millipore Dr Christine Daly christine.daly@merckgroup.com www.millipore.com Tel: 07920 299452 232 Ugg Mere Court Road, Huntingdon PE26 2RJ

Merck Millipore is the Life Science division of Merck KGaA of Germany and offers a broad range of innovative, performance products, services and business relationships that enable our customersâ&#x20AC;&#x2122; success in research, development and production of biotech and pharmaceutical drug therapies. Through dedicated collaboration on new scientific and engineering insights, and as one of the top three R&D investors in the Life Science Tools industry, Merck Millipore serves as a strategic partner to customers and helps advance the promise of life science. Headquartered in Billerica, Massachusetts, the division has around 10,000 employees and operations in 64 countries. Merck Millipore operates as EMD Millipore in the U.S. and Canada.

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Meritas Consulting Ltd

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www.meritas-international.com

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Tel: 01787 242136 07788 203143

Meritas International and Consulting is an organisation specialising in healthcare consulting and interim assignments; mentoring and coaching.

11 Priory Gardens, Sudbury, Suffolk CO10 2AF

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Mewburn Ellis LLP Dr Nick Sutcliffe nick.sutcliffe@mewburn,com www.mewburn.com Tel: 01223 420383 Fax: 01223 423792 Newnham House, Cambridge Business Park, Cambridge CB4 0WZ

Mills and Reeve LLP Isabel Napper

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isabel.napper@mills-reeve.com

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Tel: 01223 222379

www.mills-reeve.com

Fax: 01223 222591

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Mewburn Ellis LLP has one of the largest groups of patent attorneys specialising in biotechnology and life sciences in Europe. We have expertise in drafting and prosecuting patent applications in UK, Europe and worldwide, as well as due diligence work; portfolio management; strategic patent advice; infringment opinions and Oppositions and Appeals at the European Patent Office. Our proactive approach reflects the high level work we do for a wide range of clients, including world renowned biotech companies, SMEs, start-ups, spin-outs, universities, charities, and funding bodies.

Francis House, 112 Hills Road, Cambridge CB2 1PH

Mills & Reeve is a leading UK law firm in the life sciences sector. Our expertise includes advising pharmaceutical and medical device companies, government institutions, healthcare and academic institutions on IP protection and enforcement as well as related issues including licensing, MTAs, human tissue supply, stem cells, clinical trials and medical devices. We have extensive experience in the EU, USA, China and other countries, allowing us to help you achieve your global aspirations. We can help you with any concerns you may face with outsourcing agreements and collaborations, manufacturing and distribution. Our life sciences group is a full service practice with top ranking lawyers in corporate finance and funding enabling us to support your company from seed to listing and beyond. We represent leading biotech companies, investors, key NHS organisations, and world-class universities. Recent work has included patent licences and litigation, major research collaborations, clinical trials and pharmaceutical joint ventures.

Mintz Levin Cohn Ferris Glovsky and Popeo LLP Ms Susan Foster sfoster@mintz.com www.mintz.com Tel: 0207 776 7330 Alder Castle, 10 Noble Street, London EC2V 7JX

One Nucleus Directory 2012

Mintz Levin is a full-service law firm with 450 lawyers in the UK and US. Working with biotech, pharmaceutical, and medical device manufacturers - and their investors and underwriters - our Life Sciences practice is one of the largest in the world. We also work extensively with academic and medical institutions, hospitals and physicians, and other health care clients. Because our UK and US offices work seamlessly together, we have a unique ability to advise clients on their trans-Atlantic and international operations. Our clients include emerging companies as well as established privately-held and publicly-listed companies. With practice strengths in areas such as intellectual property, company formation and governance, and venture capital and financing as well as deep industry experience in life sciences, health care, energy, clean technology, and information technology, we serve as a springboard for many UK firms entering the US market and expanding internationally

Miranda Weston-Smith Miranda Weston-Smith Miranda@mws-consulting.co.uk mws-consulting.co.uk Tel: 01223 511664 St John’s Innovation Centre, Cowley Road, Cambridge CB4 0WS

A Miranda Weston-Smith advises entrepreneurs, companies and universities on business development in healthcare and biotech. She is experienced in intellectual property negotiations, business planning and fundraising. Starting a Technology Company, the book Miranda wrote while at Cambridge Enterprise, University of Cambridge is available at enquiries@enterprise.cam.ac.uk. Partner organisations include 4D Biomedical, Cambridge Healthcare and Biotech, Centre for Entrepreneurial Learning and St John’s Innovation Centre.

Miranda is a graduate in Natural Sciences, University of Cambridge, holds the AAT Diploma in Accounting, and a Fellow of the Linnaean Society.

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MNX - Midnite Express

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www.mnx.com

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16 Saxon Way, Harmondsworth, Middlesex UB7 0LW

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MorphoSys UK Ltd T/A AbD Serotec sales.uk@abdserotec.com www.abdserotec.com Tel: 01865 852700 Fax: 01865 373899 Endeavour House, Langford Business Park, Langford Lane, Kidlington OX5 1GE

AbD Serotec is a division of MorphoSys, one of the world’s leading antibody technology companies. AbD Serotec prides itself on its commitment to providing its customers in research and industry the ?highest quality products and services. AbD Serotec’s production facility in ?Oxford, UK, is certified to the quality management standards ISO 9001 and ISO 13485. Our products and services include: • More than 15,000 antibodies & immunological reagents • Custom monoclonal & polyclonal antibodies • Large & small scale antibody production & conjugation services Our reputation has been earned through long-term collaborations and strategic partnerships with key life science and diagnostic companies around the world.

Tel: 020 7920 4025 One Ropemaker Street, London EC2Y 9AW

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Morrison & Foerster (UK) LLP www.mofo.com

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Morrison & Foerster provides a full-range of legal services to clients in the biotechnology, medical device, pharmaceutical and healthcare industries. The firm’s Life Sciences Group work with life sciences companies at every phase of their growth cycle, including formation and financing of early-stage ventures; start-up technology transfer; structuring and negotiating licenses, R&D collaborations; planning and developing IP portfolios; M&A; IPOs and follow-on securities offerings; protecting and defending IP rights; and developing and financing new research and manufacturing facilities. We are uniquely positioned to serve the global life sciences industry with over 130 lawyers in the U.S., Asia and Europe. Our European life sciences practice offers unrivalled transactional expertise. Led by Julian Thurston, one of Europe’s top commercial life sciences attorneys, Paul Claydon and James Gubbins, two of Europe’s top corporate life sciences attorneys, we provide advice on the full-range of issues relevant to Life Science Companies, their investors and their Investment Bank Advisers.

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MRC Technology Jonathan McGee info@tech.mrc.ac.uk www.mrctechnology.org Tel: 020 7391 2700

V MRC Technology is a technology transfer company responsible for translating cutting edge scientific discoveries into commercial products. MRC Technology adds value to cutting edge scientific discoveries through strategic patent protection and creative licensing of intellectual property (IP), through partnered research or through further scientific development. MRC Technology also has small molecule drug discovery and therapeutic antibody facilities, providing lead stage therapeutic assets to pharmaceutical and biotechnology companies.

Fax: 020 7391 2800

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7th Floor Lynton House, 7-12 Tavistock Square, London WC1H 9LT

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MS Therapeutics Ltd info@mstherapeutics.com www.mstherapeutics.com

MS Therapeutics Ltd is a Speciality Pharmaceutical company focused on the development of new medicines for multiple sclerosis and related disorders

Beechey House, 87 Church Street, Crowthorne RG45 7AW

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Mundipharma International Ltd

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www.mundipharma.co.uk

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194 Cambridge Science Park, Milton Road, Cambridge CB4 0AB

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National Skills Academy Process Industries Kevin Thrower k.thrower@process.nsacademy .co.uk www.process.nsacademy.co.uk

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Tel: 07894 483694

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5 Pioneer Court, Morton Palms Business Park, Darlington DL1 4WD

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Cristina Quiles

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Tel: 34 93 402 0164 075 008 03 008

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Vintage Yard, 59-63 Bermondsey Street, London SE1 3XF

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www.nsc-tec.com

NEUROSCIENCE TECHNOLOGIES is a biomedical company with expertise in human pain neurophysiology that helps the pharmaceutical and biotechnology industries by assessing the activity of compounds through microneurography, providing evidence that is directly translational from basic research to clinical efficacy. We are experts on the neurophysiological assessment of the peripheral and central nociceptive pathways, both preclinically and in humans. Our services provide a direct translation of results from basic research to the clinical setting. We serve the pain drug development programs through a solid proof-of-concept model based on the detection and quantification of spontaneous activity in pain fibers.

New England Biolabs (UK) Ltd www.neb.uk.com 75/77 Knowl Piece, Wilbury Way, Hitchin SG4 0TY

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The National Skills Academy Process Industries, part of the Cogent group of companies, has had its remit extended to address skills and training needs in the biotechnology sector. The Academy aims to create a highly skilled biotechnology workforce capable of competing on a global stage. Its main focus is to encourage employers to engage in frontline staff training so that their current workforce can achieve accredited qualifications, progress their careers and help to develop the business. The Skills Academy works alongside training providers and educational bodies to ensure that more people enter the industry equipped with the skills the industry needs. It also works with employers to identify gaps in staff training and find solutions to upskill the workforce. The Skills Academy has extensive commitment from employers to play a key role in helping to create the high performing workforce of tomorrow by investing in skills and training within their companies.

Neuroscience Technologies Ltd. cquiles@nsc-tec.com

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The Purdue/Mundipharma/Napp independent associated companies are world leaders in the development and marketing of proprietary analgesics for the treatment of moderate to severe pain, with products such as Targin, BuTrans, Norspan, OxyContin and Palladone. A growing franchise in novel oncology therapies comprises the marketed products DepoCyte and Ribomustin, and Fodosine, which is currently in clinical development.

Mundipharma has the European rights to FlutiForm and is conducting Phase III clinical trials as an entry strategy into the respiratory market. Product sales are made in over 100 countries worldwide, supported by a worldwide sales and marketing operation that comprises over 1 000 field sales representatives in Europe. The companies are committed to building their presence in the areas of analgesia, oncology and respiratory medicine. Inlicensing is a key component of the companies’ portfolio building strategy. Substantial medical research and regulatory affairs functions are located in the UK (Cambridge) and Germany, with expertise in handling European clinical research and worldwide product registrations.

One Nucleus Directory 2012

Both NEB and CST produce reagents for drug discovery, basic research and scale up in cellular and molecular biology, including custom and bulk preps. NEB’s interests include enzymes used at the DNA, RNA and protein levels. These extend from PCR and Next-gen sequencing to protein expression and analysis. CST’s interests cover cell signalling and including phospho-analysis/profiling. CST produces antibodies that are screened and validated for particular applications (HCS, Flow, IHC etc). CST has novel antibody generating technologies. For more information on CST products and services, please email info@uk.neb.com

Norwich Research Park Dr Matthew Hills matthew.hills@nrp.org.uk www.nrp.org.uk Tel: 01603 274441 NRP Innovation Centre, Norwich Research Park, Colney Lane, Norwich NR4 7GJ

A The Norwich Research Park is a community of innovative businesses and research scientists with over 11,000 staff based at the University of East Anglia, four life science research institutes and a busy teaching hospital.

The Park has 60,000 sq ft of commercial laboratory and office space in its NRP Innovation Centre and Norwich BioIncubator. The government, through BIS/BBSRC, is investing £26 million in infrastructure for the NRP to support expansion of commercial activity. Land is available for new-build to suit. Enquiries to the NRP office are welcomed. The NRP has a great deal of biotech, biomedical and clinical expertise and facilities that can be accessed via the NRP office (see website) including the genome analysis centre, clinical trials unit and biomedical research centre at UEA. The NRP office promotes the research capabilities and expertise of the partner organisations and fosters business development on the Park.

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Novartis Pharma AG

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www.novartis.com

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Tel: +41 6132 41164

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WSJ - 202.513, Basel Switzerland CH-4002

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O2h Sunil Shah sunil@o2h.com www.o2h.com Tel: 01223 437014

O2h is a privately owned, medicinal chemistry service company founded in 2003. The group has two sites, a project management office in Cambridge, UK and its operations in Ahmedabad India. Our Indian base allows us to provide incredible speed/value compared to companies with operations in the West. O2h has developed a 10,000 sq m research facility, this has capacity for 28 dedicated 12 FH lab units. Aside from our core chemistry strengths, O2h have also been enhancing its in-house ADME capability. Together with the new state-of-the-art campus and ADME facilities, O2h is geared towards providing teir1 services for managed discovery research.

Fax: 01223 437013 23 Cambridge Science Park, Milton Road, Cambridge CB4 0EY

vishal.patel@oamps.co.uk David.baker@oamps.co.uk www.oampslondon.com Tel: 0207 375 9094 0207 929 6889 6th Floor, 10 Fenchurch Street, London EC3M 3BE

rod.weedon@officeteam.co.uk www.officeteam.co.uk

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P Oamps provide insurance and risk management solutions for companies in the Life Science and Technology Sectors. We are a Lloyds broker based in the City of London allowing us immediate direct access with all the key specialist insurers supporting the Sector. We are also members of a global-network to ensure we have the capability to assist our clients with overseas exposures. We are not your typical insurance broker and have over many years developed a highly experienced, friendly and approachable team of advisors who are dedicated to assisting a variety of businesses and entrepreneurs in the Sector. We are proud to be considered a trusted partner to many of our clients, with whom we have developed lasting relationships over the past 20 years.

Throughout their development we have been able to support them with bespoke insurance and risk management solutions for clinical trials, fundraisers, product launches, supply chain or regulatory issues, acquisitions and IPO’s.

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Office Team Rod Weedon

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OAMPS Special Risks Vishal Patel & David Baker

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V OfficeTeam are the leading independent Office Services and Supplies Company in the UK. Uniquely structured to provide a local next day service nationally.Specialist areas: Office Supplies, Furniture, Print and Print Management, File Data and Storage, Digital Dictation & Transcription, Document Production, Workwear, Catering & Janitorial Supplies, Computer Consumables, Photocopier and Printer Supply and Maintenance.

Tel: 01284 767711 Fax: 01284 760405

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29 Eastern Way, Bury St. Edmunds, IP32 7AB

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OncoLytika Ltd Dr Mark Eccleston mark.eccleston@oncolytika.com www.oncolytika.com Tel: 0560 107 8911 Fax: 05601 078 911

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1 The Firs, Wilburton, Ely CB6 3FL

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Osborne Clarke

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Dr Janita Good

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www.osborneclarke.com

janita.good@osborneclarke.com

Tel: 0118 9252064

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Oury Clark Life Sciences James Oury james.oury@ouryclark.com www.ouryclark.com

Fax: 0207 067 4301 10 John Street, London WC1N 2EB

Oxbridge Biotechnology Roundtable info@oxbridgebiotech.com

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Flat 3, Fettlers House, Walton Well Road, Oxford OX2 6GE

Tel: 07583 873540

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Oxbridge Biotechnology Roundtable (OBR) a new association that fills an important and unmet need: an inter-campus forum that educates the next wave of innovators and helps bring their ideas to fruition. Our goal is to create a pan-UK network of young innovators that connects idea-holders to the industry resources necessary to move ideas forward. OBR builds its network and engages its members via a three-pronged approach: • Various speaker series provide unique industry perspective • Industry immersion internships provide hands-on experience, for teams assembled from students across different campuses.

Allows industry a pro bono preview of Oxbridge talent, and forges connections between innovators at different campuses. • Communications outreaches distributes interdisciplinary commentary, and keeps our network engaged with industry and each other Furthermore, as we aim to foster conversations and increase knowledge transfer between innovators, advisers and investors throughout the UK, OBR has established a multifaceted online network. With a strong focus on the user experience, the online component will add broad outreach without diminishing the role of personal contact. Our goal is to tear down the barriers that prevent good ideas from reaching the advisers and investors who facilitate their commercialization. We are young and we are growing. After just two months, OBR expanded from Oxford to Cambridge and now another two months later, is all set to expand to London.

Page White and Farrer www.pagewhite.com Tel: 0207 8317929 Bedford House, John Street, London WC1N 2BF

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Oury Clark has a dedicated Healthcare Technology Services Group, providing an inter-disciplinary professional advisory service to our clients in this sector. These services include but are not limited to intellectual property protection, licensing, employment law, research and development tax advice, share incentive schemes and general accounting, taxation and legal advice.

Tel: 0207 067 4300

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Osborne Clarke is a leading European law firm providing business-focused solutions that take full account of the commercial drivers and current trends in the market practice We have strength in depth and breadth. Osborne Clarke boasts a headcount of around 600 staff across Europe We have a strategic focus on key sectors. As a firm, we focus on the chosen sectors of our client base. For example, digital business, lifesciences & healthcare are key sectors for us We are top ranked in legal directories. For instance we are ranked highly for mid-market M&A, venture capital, intellectual property, commercial and competition.

Apex Plaza, Forbury Road, Reading RG1 1AX

www.oxbridgebiotech.com

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Oncolytika is an integrated theranostics company developing diagnostics, imaging agents and therapeutics in the oncology area.

One Nucleus Directory 2012

With each of our practitioners focusing on particular technologies or legal disciplines, we can provide you with a winning combination of technical knowledge, business acumen and a sound appreciation of the workings of the law. IP has become a global issue as national boundaries are transcended by new technology, so an international approach is now vital. We have expertise in handling IP in all countries, and we maintain a strong working relationship with highly respected firms throughout the world. Our biosciences practice serves all areas of biotechnology including drug discovery and delivery, molecular biology, immunology, diagnostics and bioinformatics. We represent clients before the UK and European Patent. Our patent services include the following: - drafting, filing and prosecution of patent applications - defending clients’ European patents against opposition - drafting and filing oppositions to third party European patents - applications for supplementary protection certificates - opinions on infringement and validity of third party patents - surveillance of third party patent activity - assistance in due diligence process - assistance in litigation

PAION UK Limited info@paion.com www.paion.com/en Tel: 01223 257 703 Fax: 01223 257 604 Compass House, Vision Park, Chivers Way, Histon, Cambridgeshire CB4 9ZR

A PAION UK Ltd is a subsidiary of PAION AG, a biopharmaceutical company headquartered in Aachen, Germany.

PAION is specialized in developing and commercializing innovative drugs for the hospital-based treatment in indications for which there is a substantial unmet medical need. After proof of concept in humans the strategy is to out-license or co-develop the drug candidates with pharma partners. Thus revenues can be generated at an early stage, decreasing development costs and risks. The company further profits from the receipt of payments for reaching clinical and commercial milestones and receiving royalties after market approval of the drugs.

Further upside can be generated from co-commercialisation activities. PAION is listed at the Frankfurt Stock Exchange (Prime Standard Regulated Market, Stock Symbol PA8, ISIN DE000A0B65S3).

LifeSciences.EU@pall.com www.pall.com Tel: 02392 303358 Walton Road, Portsmouth PO6 1TD

Chad.Simon@parexel.com www.parexel.com Tel: 01895 614908 Fax: 020 8422 6070 Level 7 Northwick Park Hospital, Watford Road, Harrow HA1 3UJ

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F The life sciences industry is both driven and united by its need for speed to market, product reliability and economics. Pall’s leading edge filtration, separation and purification technologies and services play an essential and pivotal role in this industry’s ability to achieve these goals. In the laboratory, Pall products help to facilitate the drug discovery and development process to get innovative drugs to the market faster. In Biopharmaceuticals, Pall filtration, chromatography, sampling, monitoring and quality assurance products, together with technical services in validation, assays and process optimization are applicable to laboratory and pilot-scale development, aseptic processing, biologicals, bioprocessing, fermentation and downstream processing.

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Parexel International Chad Simon

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PALL Life Sciences Henry Charlton

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PAREXEL is a leading global bio/pharmaceutical services organization that helps clients expedite time-to-market through our development and launch services. These include a broad range of clinical development capabilities, integrated advanced technologies, regulatory affairs consulting, and commercialization services. Over the past 27 years, PAREXEL has developed significant expertise to assist clients in the worldwide pharmaceutical, biotechnology and medical device industries with the development and launch of their products in order to bring safe and effective treatments to the global marketplace for the patients who need them. Headquartered near Boston, Massachusetts, PAREXEL operates in 70 locations throughout 54 countries around the world, and has over 9,500 employees.

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Tel: 01379 672379

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Wooley Road, Alconbury, Huntingdon PE28 4HS

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Patheon UK Ltd www.patheon.com Kingfisher Drive, Covingham, Swindon SN3 5BZ

V Patheon is a leading global provider of contract dosage form development and manufacturing services to the pharmaceutical and biotechnology industries.

We provide fully integrated contract manufacturing and development solutions to our customers, from early development through to high-volume commercial manufacturing and packaging. Offering world-class facilities and expertise, and an unwavering focus on service quality, Patheon is uniquely positioned to serve as the pharmaceutical industry’s preferred strategic partner.

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PERA www.pera.com Tel: 01664 501436 Nottingham Road, Melton Mowbray LE13 0PB

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PerkinElmer

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Mary Donlan, Director, Informatics European Marketing

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mary.donlan@perkinelmer.com

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Tel: 01223 443424

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www.cambridgesoft.com

1 Signet Court, Swann’s Road, Cambridge CB5 8LA

PerkinElmer is a market leader in software solutions and services for the chemical, biotechnology and pharmaceutical industries. PerkinElmer has earned an enviable reputation as a supplier of Enterprise informatics solutions across a very broad range of scientific disciplines, including providing Electronic Laboratory Notebook systems to four of the world’s top five Pharmaceutical companies. PerkinElmer provides: Enterprise solutions, desktop software, scientific databases, and professional services for biotechnology, drug discovery and chemical research, including software, databases, and web sites which enable customers to create, analyze and communicate chemical, biological, and scientific information more effectively. PerkinElmer’s products are used primarily in the pharmaceutical, biotechnology and chemical industries, as well as in higher education and in academic and government research. The company’s principal software offering, ChemBioOffice is the de facto standard and primary communication tool on the chemist’s desktop. ChemBioOffice Enterprise enables research information organizations to manage and share life science information enterprise-wide.

Pfizer Ltd www.pfizer.co.uk Tel: 01304 616161 Granta Park, Pfizer Ltd ipc 300, Cambridge CB21 6GP

Pfizer is the worlds largest pharmaceutical company, operating in 180 countries worldwide.

Pfizer employs over 1,000 staff in various sites throughout the UK, including DCoE Cambridge (dedicated to the development of drug delivery devices) and Neusentis (consolidating Pfizer’s Pain & Sensory Disorders and Regenerative Medicine units into a new biotech like unit).

Pfizer’s current key pharmaceutical products include – Lipitor, Lyrica, Celebrex, Viagra, Zoloft, Norvasc, Enbrel and Aricept

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Pharma International Tel: +41 61 483 09 78 Fax: +41 61 483 09 79 Innovation Centre, Gewerbestrasse 14, Allschwil, Switzerland CH4123

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Pharmaceutical Equipment Validation (PEV) Ltd www.pev.co.uk Tel: 01256 698049 Fax: 01256 698549 Pinewood, Chineham Business Park, Basingstoke RG24 8AL

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PharmaMorph John Whittaker

A Engaged in consulting with early-stage Health Care companies particularly with an oncology interest.

John.Whittaker@btclick.com Tel: 020 8992 1459

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Fax: 020 8896 3083 12 Chatsworth Gardens, Acton W3 9LN

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PharmaWave Ltd Paolo Bessieres, CEO paolo.bessieres@pharmawave .co.uk www.pharmawave.co.uk 28 Abbey Road, St. John’s Wood, London NW8 9AX

Thanks to its extensive network of contacts, PharmaWave is able to reach decision making people in Japan and throughout Asia. PharmaWave supports Western biotech and healthcare companies by identifying the most suitable partners, structuring and negotiating corporate transactions, and keeping in touch locally with may-be partners, until after the deal has been secured. PharmaWave strongly advises Western companies wishing to enter Japan with their products and technologies to approach this market simultaneously to Europe and US, not to lose valuable royalty income. Pharmawave adopts flexible business models.

business@pharmidex.com www.pharmidex.com Tel: 0870 240 5978 Fax: 0845 125 9586

Pharmidex provides an extensive range of ADMET/PK (in vitro/in vivo) and safety expertise to underpin its world leading CNS position. Existing platform technologies or bespoke studies address client specific needs and are rapidly undertaken by highly qualified scientists with academic and industry background. With extensive in-house expertise, we risk manage all project issues and associated regulatory challenges, focusing on the key data, decision-points and milestones, allowing our clients to progress their programmes and portfolio. Focused customer interaction, tailored support, high quality data, fast turnaround times and cost efficiency are attributes that makes Pharmidex your partner of choice.

www.phflifesciences.co.uk Tel: 01925 859644 07714 486549

PHF Life Sciences is a specialist division of Pharmfinders Ltd, one of the UK’s leading Retail, Healthcare and Life Science recruiters. We provide both search and selection and contingent recruitment solutions to the UK and International life science community. We work closely with companies in the fields of biotechnology, diagnostics, medical devices, medtech and healthcare (both NHS and private), ensuring we deliver a completely holistic solution to a full range of recruitment requirements.

www.phgfoundation.org Strangeways Research Laboratory, Worts Causeway, Cambridge CB1 8RN

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PHG Foundation carol.lyon@phgfoundation.org

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Suite 109/110 Lovell House, Birchwood Park, Warrington WA3 6FW

Carol Lyon

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PHF Life Sciences andy@phfrecruitment.co.uk

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3rd Floor, 14 Hanover Street, London W1S 1YH

Andy Cuthbert

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Pharmidex Pharmaceutical Services Ltd Dr Gary Manchee Mr Dean Palmer

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V PHG Foundation is an independent not-for-profit with a mission to “make science work for health”. Our expert research, analysis and change management services help governments and health systems exploit developments in bioscience to improve population health. Our policy and service development projects aim to accelerate the effective and responsible use of bioscience in health care. We are also a think-tank, contributing ideas and stimulating and creating space for debate by policy makers, health professionals and the public on technological innovations for health.

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Philip Bedford Consulting Ltd www.philipbedford.com 234 Queen Edith’s Way, Cambridge CB1 8NL

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Phoenix Forums Ltd

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68 Huntingdon Road, London N2 9DU

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Tel: 020 8442 2367

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Physiomics plc info@physiomics-plc.com www.physiomics-plc.com Magdalen Centre, Oxford Science Park, Oxford OX4 4GA

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PiR Limited Sally Hope, Managing Director

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resourcing@pir-resourcing.com

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14B Raleigh House, Compass Point Business Park, Stocks Bridge Way, St Ives, PE27 5JL

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Tel: 0844 880 4340

PiR is a brand synonymous with providing innovative senior resourcing solutions to life science organisations. As a result of our exclusive focus on the sector, we have an understanding of many of the issues faced by pharmaceutical, biotechnology, diagnostic and medical device companies in the 21st century. PiR offer a range of resourcing services, core to these are senior permanent and interim staff. • Permanent Resourcing Solutions • Interim Management Services • Talent Identification • Board Evaluation & HR services • Non Executive Directors PiR’s expertise is particularly evident across functions in high demand. These include Medical, Regulatory, Programme Management, Supply Chain, Market Access, Health Economics & Outcomes Research (HEOR), Pricing & Reimbursement and senior level Commercial roles. Industry expert NEDs are also part of PiR’s portfolio.

Our objective is to identify senior talent to support your campaign for competitive and innovative advantage. You will find our approach to shared risk attractive and relevant in the current market. Add to this our industry reputation and well developed network of contacts and you have a formula which is focused on delivering results and value.

Plastid AS Rosalind Russell rosalind.russell@plastid.no www.plastid.no Prof Olav Hanssensvei 7A, P B 8034, Stavanger, Norway 4068

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Physiomics’ Virtual Tumour technology helps companies in the oncology field to determine optimal doses, schedules and combinations for pre-clinical animal studies. These optimised regimens can then be used as part of the planning process for clinical trials. An optimised regimen can make the difference between success and failure of an NCE or NBE. Our computational modelling approach has been validated with a number of big pharma and biotech customers. Virtual Tumour provides the following key benefits: 1. Improve success rates for oncology candidates entering clinical studies, by increasing efficacy. 2. Reduce the time taken to do proof-of-principle studies. 3. Reduce the cost of xenograft study programmes (fewer experiments needed). 4.

Provide regulatory agencies with a rationale for the design of a clinical study programme. Virtual Tumour can be accessed through: • Fee-for service. • Reduced up-front fees with downstream milestones/success payments. • Full risk-sharing for selected projects. • Licensing

One Nucleus Directory 2012

Plastid AS has a unique technology for the simple transformation of a plant’s plastid genome. New proteins or traits can be introduced into the plants that may contribute to crop improvement - pest resistance, drought tolerance etc. The technique has efficiency advantages over existing competition through simplicity and repeatability, as well as the plastid feature of no gene silencing. The transformed plants can also be used as biofactories - average protein expression levels are 10% of total cellular protein and the method can be used to express protein that cannot be made in any other system.

Potter Clarkson LLP Jane Wainwright jane.wainwright@potterclarkson .com www.potterclarkson.com Park View House, 58 The Ropewalk, Nottingham NG1 5DD

A Potter Clarkson LLP is a leading European firm of patent and trade mark attorneys based in Nottingham, UK. The company advises clients worldwide on patents, trade marks, designs and related aspects of intellectual property (IP). Potter Clarkson works with start-ups and early-stage companies to multinationals, turning inventions into commercial products. The biotechnology and chemistry sectors are covered by 23 Potter Clarkson patent experts, most of whom hold a PhD in a relevant biological or chemical discipline and have research expertise in the pharmaceutical industry or academia.

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Power Solutions info@powersolutionsuk.com www.powersolutionsuk.com Tel: 01244 391500 Fax: 08452 991379 Oakbase House, Trafford Street, Chester CH1 3HP

Power Solutions are a support supplier for One Nucleus offering an ongoing no-cost, energy consultancy service for our clients.

We currently look after 8,500 sites in the UK, negotiating low energy prices for our clients, whilst also managing their energy requirements. We are dedicated to providing a world class service for the One Nucleus membership in reducing energy costs and managing their consumption to ensure best value for the future as well as keeping an eye on the environment.

As a member of One Nucleus we would like to offer our services on a no-cost, and no obligation basis. Our process is simple in that we analyse and audit a recent bill and ascertain when the best time would be to tender and subsequently negotiate the best rate for each individual site. From here, we provide an ongoing energy management service, whereby we deal with any questions or issues that are energy related again at no cost to you.

www.ppmld.com Tel: 0208 852 2758 Fax: 0208 8523 657 12 Micheldever Road, London SE12 8LX

We help people make projects and partnerships work effectively.

We assess companies’ and individuals’ current capabilities and establish which developments will make maximum impact on output. This may be by aligning company systems, increasing role clarity, or establishing productive operating frameworks between partner organisations.

We train and coach people to get projects up and running and build teams that harness contributions across functional and company boundaries. We enable people to lead, manage risk, influence effectively, process major decisions, and inspire innovation.

We deliver training and consulting for One Nucleus and coordinate the Projects and Partnering Special Interest Group

enquiries@precos.co.uk www.precos.co.uk Tel: 0870 166 6234 Fax: 0870 166 6233 Hillcrest, Dodgeford Lane, Belton, Loughborough LE12 9TE

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Pre Clinical Oncology Services Ltd Jon Waterman-Smith

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PRECOS provides PRE-Clinical Oncology research Services. We have a track record of providing advanced oncology models and expertise in: • The PREdict Platform: From patient tissue to validated models. • The PREval Platform: Target validation in in vitro as well as in vivo systems. • The PREcise Platform: Validated, accurate, reproducible in vitro and in vivo models. • Bioluminescent and fluorescent models enabling real-time quantitative measurement of tumour progression and drug efficacy. • Orthotopic and metastatic models. • Extensive experience in combination studies. • Focusing on your success, providing expert advice from model/ study design to result interpretation. Why not find out how we can make a vital difference to your oncology research programmes today?

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Precious Cells international Ltd

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www.precious-cells.com

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Tel: 01895 367980 Gardiner Building, Brunel Science Park, Uxbridge UB83PQ

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PreScript Communications Ltd Barbara Fagg barbarafagg@prescript.co.uk www.prescript.co.uk Tel: 01462 491171 Fax: 01462 896781 15 Royston Road, Baldock SG7 6NW

PreScript is a communications agency specialising in global scientific, medical and marketing communications. Our projects are mostly commissioned by international biotechnology and pharmaceutical companies and are targeted at both professional public and internal audiences. Our company has particular strengths in: training and project management, copywriting, design and production, IT, video and digital media including iPad development, which translate into a high level of service and attention to detail. PreScript offers an exceptional combination of experienced personnel, a comprehensive skill base, timely execution, quality and a commitment to customer service and satisfaction.

We work in partnership with our clients, listening closely to your requirements and feedback in order to pro-actively deliver a creative, appropriate and cost-effective solution. Whether you need help producing blended learning, patient education material, product or skills training programmes, congress support, marketing materials or to revamp your website or corporate identity, then look no further. We will see your project through from concept to completion. No job is too small and no project too challenging. You can count on PreScript to deliver timely, quality material to your specifications and within budget. Our major clients include: • Novartis (multiple products/accounts) • Dako • Johnson & Johnson • Almirall • GSK

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PricewaterhouseCoopers LLP

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www.pwc.com

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Abacus House, Castle Park, Cambridge

PwC is founded on a culture of partnership with a strong commercial focus. This is reflected in our vision:”One firm - a powerhouse of a commercial enterprise that does the right thing for our clients, our people and our communities.” Our goal is to build the iconic professional services firm, always front of mind, because we aim to be the best. We set the standard and we drive the agenda for our profession.

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Prism Training and Consultancy Ltd Iain Wilson iainw@prismtc.co.uk www.prismtc.co.uk

At PRISMTC, we solve problems. We provide specialist statistical support to scientists and engineers. Whatever your statistical background, we can help improve the effectiveness of your Design of Experiments, Multivariate Analyses, Six Sigma, and more.... We provide statistical training, a consulting service and software tools. We are based in Cambridge (UK) and we operate internationally.

St John’s Innovation Centre, Cowley Road, Cambridge CB4 0WS

ProClinical Ltd Daniel Smart

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d.smart@proclinical.co.uk

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Tel: 0207 440 0637

www.proclinical.co.uk

ProClincial work extensively in recruiting both temporary and permanent research professionals into Regulatory, Medical, HEOR, and other clinical Research related roles within the European Pharmaceutical industry. As an established preferred supplier to some of the world’s most prestigious Big Pharma companies, ProClinical can also help emerging companies to identify, attract and secure the services of key staff to enable sustainable growth and development. ProClinical help both candidates and hiring managers to achieve their recruitment goals quickly and cost efficiently.

Fax: 0207 287 2567

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3rd Floor, 25 Gerrard Street, London W1D 6JL

Promega UK Ltd Matthew Cook, Pharma and Biotech Sales Manager matthew.cook@promega.com www.promega.com Tel: 0800 559900 07585 962903 Delta House, Southampton Science Park, Southampton SO16 7NS

One Nucleus Directory 2012

Promega Corporation’s 2,000 products enable scientists worldwide to advance their research in the life sciences, particularly genomics and cellular analysis. Our products are used by customers to understand the molecular basis of life and potential mechanisms of disease, as well as to identify attractive drug development targets.

Genomics: The company’s portfolio began with products for genomics researchers and now includes cloning systems, luciferase reporters, and amplification products as well as the original restriction and modifying enzymes. The portfolio of amplification products includes the GoTaq family of polymerases and buffers and the Plexor quantitative PCR system.

Cellular Analysis and Drug Discovery: Promega offers a range of products for cell biology and drug discovery, many of which are built upon bioluminescence technology. In 2010, Promega launched a custom assay services business for biologics and small molecule drug development.

Prosarix Ltd Dr Bill Hamilton bill.hamilton@prosarix.com www.prosarix.com Tel: 01223 870400 Newton Hall, Town Street, Newton, Cambridge CB22 7Z

A Prosarix specialises in the development and application of computational approaches to small molecules.

Prosarix has developed ProtoDiscovery™, a validated, state-of-the-art computational platform with which it is pioneering novel approaches for the identification, design and optimisation of small molecules, in silico pharmacology prediction, and biosynthetic pathway approaches. The Company has three main business activities: the provision of serviced based projects for third parties; in-house discovery, developing preclinical candidates for early-stage out-licensing; and chiral products, whereby Prosarix designs novel chiral reagent panels, EnzaCore™ SAR Explorer panels, which are manufactured using specialist biocatalysis chemistry for sale to R&D medicinal chemists.

cbonnar@prosynth.com www.prosynth.com Tel: 01787 883320 Unit 2 Bull Lane Industrial Estate, Acton, Sudbury, Suffolk CO10 0BD UK

www.ptglab.com Tel: 0161 226 6144 Fax: 0161 232 1272 Kilburn House, Manchester Science Park, Lloyd Street, North Manchester M15 6SE

ProSynth are ideally placed to work with companies to meet their organic synthesis requirements, providing high quality novel organic intermediates to progress innovative ideas in a wide range of industries. ProSynth are extremely responsive to the individual needs of our customers; providing tailor-made solutions in a timely and cost-effective manner. We are committed to pragmatic project management from your initial enquiry through to the completion of the project. ProSynth are the synthesis partner to help take your ideas from a sketch in a notebook, through small-scale trials to proof of concept and beyond. We would be delighted to discuss your requirements.

www.protogeniaconsulting. co.uk Tel: 07905 321515 P O Box 289, Ely CB7 9DR

barbara.baron@psynova.com www.psynova-neurotech.com Tel: 01223 421635

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K Proteintech is a global biotech company and a renowned centre of excellence for the manufacture and supply of antibodies and proteins to the life sciences research community. With offices in the US (Chicago), UK (Manchester) and China (Wuhan) we are always available to support your research. We believe in working closely with the life sciences research community; a research partner that provides every possible antibody you might need at a reasonable price. As all the founders of the company began as bench-side researchers, we have the deepest appreciation for the high standards that all scientists hold for their projects; we hold our products to the same standard. We profoundly believe that only if you succeed, we will succeed. In addition to pre-made antibodies, Proteintech Group also provides a wide variety of custom services including: cloning, expression, peptide synthesis and custom antibody development, visit our website to find out more.

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Protogenia Consulting Ltd offers pre-clinical and early clinical development consultancy services to the pharmaceutical / biotech industry. With over 15 years non-clinical outsourcing and project / programme management experience gained through virtual and medium sized pharmaceutical companies, the services we offer include: • Programme Management up to EOP2 • Strategic analysis and due diligence review • Regulatory submission document writing and expert review • CRO selection, contract negotiation and study management including protocol design, monitoring and report review for toxicology, safety pharmacology and ADME studies • Quality Systems and SOP management support.

In addition, we have a broad network of Drug Development contacts, and can provide expert advice on IP Strategy, Chemistry Process Development and Manufacture, Analytical Services, Pharmaceutical Development and Manufacture, Regulatory Affairs and Quality Assurance.

Psynova Neurotech Barbara Baron

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Protogenia Consulting Ltd info@protogeniaconsulting. co.uk

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Proteintech Europe Ltd europe@ptglab.com

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Prosynth Ltd Clare Bonnar

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Psynova Neurotech is exclusively focused on the commercial development and exploitation of novel biomarkers for Neuropsychiatric and other mental illnesses. Building on 12 years of ground-breaking research by its founder Prof. Sabine Bahn, Psynova Neurotech is initially concentrating on Schizophrenia and Bipolar Affective Disorder.

In 2010, our first product was launched in the USA by our partner Rules Based Medicine, Inc.; VeriPsych™ is the first and only blood test to aid a psychiatrist in the diagnosis of recent-onset schizophrenia.

St John’s Innovation Centre, Cowley Road, Cambridge CB4 0WS

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Pure Resourcing Solutions www.prs.uk.com Tel: 01223 209888

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Established in 2002, Pure Resourcing Solutions specialises in end-to-end recruitment and retention solutions for public and private companies across the East of England. Pure Resourcing Solutions has established itself as a leader and a trusted advisor in the Accountancy, Financial Services, HR, Marketing and Office recruitment markets. In addition to the core recruitment services offered, complementary services include Assessment Centres, Proficiency Testing, Psychometric Testing, Training, Salary Benchmarking and Coaching.

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www.qscl.co.uk

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Tel: 01423 522406

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Fax: 01423 526005

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1st floor office suite, 7 Cheltenham Mount, Harrogate HG1 1DW

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QPS (UK) Fabien Du Fraisse Fabien.du.fraisse@qps.com www.qps.com Tel: 01234 262052 95 Stanley Street, Bedford MK41 7RX UK

Contact QPS’ global team of qualified and experienced professionals to speed up drug discovery and development programs in the following six key R&D areas: DMPK: QPS offers you immediate access to a team of senior scientists with decades of pharmaceutical and biotech drug discovery and development experience.

Toxicology: QPS offers you comprehensive preclinical packages to support your IND and NDA regulatory submissions with high-quality toxicology data Bioanalytical: QPS offers you one of the world’s largest capacities in bioanalysis for small molecules and biologics, with bioanalytical facilities in the USA, Europe, India and Taiwan Translational Medicine: QPS offers you specialised biomarker assay capabilities in various therapeutic niche areas, which enable you to follow targeted therapies and personalised medicines. Early Stage Clinical: QPS offers you 400 phase I beds on three continents - 24 in the Netherlands, 40 in Taiwan, 92 in India and 240 in the USA. Late Stage Clinical:QPS offers you clinical research operations in the US, Netherlands, India, and Taiwan

Quality Care Cleaning Ltd Paul Heales

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paul@qualitycarecleaning.co.uk

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Copley Farm Business Park, Cambridge Road, Babraham, Cambridge CB22 3GN

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QSCL provides regulatory development strategy, project management and technical support to the pharmaceutical industry. Our in-depth knowledge of the development process is based on direct experience and we work in partnership with you to achieve: • efficient, cost effective pharmaceutical development; • outsourcing and management of nonclinical and clinical studies; • preparation of regulatory submission and nonclinical reviews; • access to consultants in a wide range of specialized areas.

www.qualitycarecleaning.co.uk

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Quay Pharmaceuticals Ltd Maireadh A. Pedersen www.quaypharma.com Tel: 01512 039818 Quay House, 28 Parkway, Deeside Industrial Park, Flintshire CH5 2NS

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One Nucleus Directory 2012

Quay Pharmaceuticals is experienced in providing a comprehensive out-sourcing service for formulation, analytical development and clinical trial manufacture and supply for pharmaceutical and biotechnology companies world-wide. From MHRA licensed and FDA registered facilities Quay provides; • pre-clinical to commercial formulation development • novel drug delivery system design • analytical – transfer or method development and validation • ICH stability testing • clinical trial manufacture through Phase IIb in class 100,000 (ISO 8) environment o conventional, coated and controlled release tablets and capsules o powder, liquid / semisolid fill capsules o liquid /semi solid formulations (e.g. nasal and oral solutions, creams) o pellets / spheroids and extrudates o medical devices • packing and labelling • full QC testing services • QP certification

Quebec Government Office

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Patrick Philip

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patrick.philip@mri.gouv.qc.ca www.gouv.qc.ca

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Tel: 0207 766 5920 Fax: 0207 930 7938

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59 Pall Mall, London SW1Y 5JH

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Queen Mary Innovation Ltd

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b.cox@qmul.ac.uk www.qminnovation.co.uk Tel: 02078 825278

QMI is the IP commercialisation company responsible for the identification, protection and exploitation of IP arising from the research base of Queen Mary, University of London. We provide professional support for a range of academic-business partnerships including research collaborations, technology licensing and spin-out development. We offer industry and businesses access to Queen Mary’s world class research and expertise across a broad range of technology disciplines including the life sciences, medicine, dentistry, material science and engineering.

Queen Mary, University of London, Mile End Road, London E1 4NS

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Quest Diagnostics Clinical Trials- Providing Unique Solutions for Drug Development Leading provider of laboratory services in support of global clinical trials. Extensive Central Laboratory capabilities complemented by industry leading Biomarker Research and Development.

• Global Presence: 4proprietary labs (USA, UK), complemented by 5 regional labs (China, India, Singapore, Brazil and Argentina ) • Extensive test menu featuring more than 500 validated esoteric and routine biomarker assays , specialist neuroscience, genomics and Focus (their capabilities) • Proprietary predictive biomarker and Companion Diagnostics development • Broad therapeutic expertise • Global and highly cost effective supply chain and logistics expertise • High-calibre experienced project management resource • Innovative and fully integrated IT capabilities such as Real time data access via Result/View™

Mark.laycock@raumedic.com www.raumedic.com Tel: 01989 762559 Hill Court, Walford, Ross-on-Wye HR9 5QN

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Raumedic Mark Laycock

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Quest Diagnostics Clinical Trials Lynn Murphy lynn.x.murphy@questdiagnostics .com www.questdiagnostics.com/ clinicaltrials/ Tel: 07827 350 352 Fax: 0208 377 3361 Quest House, 125-135 Staines Road, Hounslow TW3 3JB

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RAUMEDIC have established a reputation for supplying high quality medical tubing and injection moulded products for a variety of medical applications including Extra Corporeal Circulation, Dialysis, Enteral Feeding and speciality catheters, and are approved suppliers to most of the leading international medical device companies.

RAUMEDIC offers a one-stop development and manufacturing program for medical tubing, injection moulding and full low volume to high volume contract manufacturing services. Our engineers will work with you to advise on materials, design and construction, together with packaging and sterilisation. We also offer full Regulatory support to enable you to CE mark your medical devices.

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Reading Scientific Services Ltd Rebecca Thomas enquiries@rssl.com www.rssl.com Whiteknights Campus, Pepper Lane, Reading RG6 6LA

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We provide a comprehensive range of services including: pharmacopoeial testing, release testing, residual solvent analysis, dissolution testing, method development stability storage management, microbiology, spectroscopy, physical sciences, microscopy, clinical sciences and training.

We continually invest in technology and people to ensure our business maintains its foundation in scientific excellence. Our multi-disciplinary teams guarantee to meet your needs for rapid results, expert personal interpretation and sound advice.

We operate within a framework of accredited quality systems and have gained extensive regulatory compliance having been inspected by the MHRA and US FDA.

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Reddie & Grose LLP Neil Thornton neil.thornton@reddie.co.uk www.reddie.co.uk Clarendon House, Cambridge CB2 8FH

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With a client base representing companies from the FT Global 500 and FTSE listed companies, Reddie & Grose LLP is recognised as a leading patent and trade mark firm. Reddie & Grose LLP prides itself on delivering intellectual property protection for businesses in both the domestic and international marketplaces with a strong professional team of over 30 people from varied scientific backgrounds. The firm consistently continues to achieve high rankings in all professional surveys. 2011’s Legal 500 recognised Reddie & Grose LLP as a high ranking firm within the patent and trade mark attorneys sector, both in London and Cambridge. The firm has a strong biotechnology, chemistry and pharmaceuticals group in the Cambridge office, with recommendations for all four partners based there. Companies/academic institutions represented in this field by Reddie & Grose LLP include: Diagnostics for the Real World, Haemostatix, Funxional Therapeutics, TCP Innovations, Cambridge Biopolymers, Babraham Bioscience Technologies, University of Cambridge, CBT Development, Oval Medical and Team Consulting.

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Remtec Search & Selection Ltd

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angelica.chhiba@remtec.co.uk

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Tel: 01223 550860

www.remtecsearch.com

Fax: 01223 847630

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Unit 1, Breaks House, Mill Court, Great Shelford CB22 5LD

RFM Associates Dr Fiona Marston fiona.marston@dial.pipex.com Tel: 0118 988 2183 Fax: 0118 988 2183 Greenfields, Croft Road, Shinfield, Berkshire RG2 9EY

www.ricerca.com Tel: 01531 827454 329 Imp du Domaine Rozier, Les Oncins 69210 France

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RFM Associates works with investment funds, commercialisation organisations and companies, to define and manage business strategy, growth and fund raising for biotechnology companies. Consultancy advice, interim or executive management focuses on: • Strategic development and leadership of businesses from concept to commercial operations • Growth of businesses by focusing on achieving added-value milestones and building strong, successful teams • Identification, assessment and implementation of innovative solutions to business problems with particular skills in relation to scientific matters and intellectual property • Negotiation of investment and commercial deals – international experience in business and venture capital roles RFM Associates is led

by Fiona Marston who has a successful track record establishing and growing biotechnology companies in a variety of therapeutic fields including infectious diseases, vaccines, oncology and Women’s Health and platforms including antibodies, biocatalysis and metabonomics.

Ricerca Biosciences

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Remtec Selection is a Cambridge based specialist lifescience and medical device recruitment company. We work across the UK and Europe for a range of roles that are listed below. Our many years of industry expertise as well as our research and project management experience enable us to manage assignments in a high quality and timely manner. We work with large global corporations as well as small investor backed start up companies.

We can offer a range of flexible service levels enabling us to tailor our offer to meet the timescales and budget requirements of our clients. Assignments we undertake Include: CEO, Sales and Marketing Directors, General Managers Health Economics Sales and Marketing managers, Regulatory Affairs, Quality Managers, Technical and Clinical positions. We also offer one nucleus members a discount of our standard fees for the first placement we make, please see the www.onenucleus.com for information

Ricerca Biosciences offers a comprehensive suite of discovery, preclinical and development services to support drug candidates from lead identification to market authorization on a global scale. Capabilities include molecular, functional and in vivo screening and profiling, as well as medicinal chemistry, radiochemistry, toxicology, API process chemistry and cGMP manufacturing of clinical and commercial API. The Discovery Pharmacology business of Ricerca offers a broad range of discovery services designed to increase the speed, precision and productivity of your activities from discovery to toxicology and includes molecular screening and profiling, cellular/functional Pharmacology, ADME-Tox, in vivo PK, Safety and Efficacy. Ricerca’s Pharmacology business offers a world class team of resources to meet the drug discovery and development needs of the pharmaceutical, biotechnology and medical device industries. In addition to the Discovery Pharmacology business, Ricerca offers comprehensive capabilities to perform general toxicity for short-term to chronic studies, genetic toxicology, reproduction and juvenile toxicology, safety pharmacology and bioanalytical services. Ricerca provides access to all species used in regulatory toxicology studies from our state-of-the-art facilities in Lyon, France, and Concord, Ohio.

Riverbank IT Management Ltd Malcolm Newdick Malcolm@riverbank.co.uk www.riverbank.co.uk Tel: 01844 278036 Fax: 01844 278015 Standhill Court, Little Haseley, Oxford OX44 7LN

One Nucleus Directory 2012

Riverbank helps growing bioscience companies by taking responsibility for all aspects of their IT. It provides all the facilities that a company would expect if they had their own IT department. Over 100 companies depend on Riverbank as their outsourced IT department. They benefit from fixed IT costs, a help desk, and management of their vital IT infrastructure – in their office, working remotely or in the cloud. Riverbank is a Microsoft Gold Partner with a Small Business Specialist qualification, and an accredited Investor in People. All work comes with a guarantee to provide unbiased advice. As one client commented about Riverbank, “You’re on our side”.

RiverRhee Consulting Elisabeth Goodman elisabeth@riverrhee.com www.riverrhee.com Tel: 07876 130817 49 Meldreth Road, Shepreth, Nr Royston, Herts SG8 6PS

A ENHANCING TEAM EFFECTIVENESS FOR GREATER PRODUCTIVITY AND IMPROVED TEAM MORALE RiverRhee Consulting is committed to helping established scientific and business support teams in the Life Sciences make the most of their time and expertise. Our goal is to help clients achieve greater productivity, quality and satisfaction in their work. We offer in-house and off-site workshop-based training, 1-to-1 guidance and consultancy to help you: o Focus on what your customers want o Simplify and streamline what you do o Optimise your use of internal information and knowledge o Ensure that your business changes succeed We help you to enhance how team members work with each other and work with you to anchor these changes within a strong strategic and cultural organisational framework. RiverRhee Consulting is a One Nucleus Support Supplier for “Team and Process Development and Training”

kay.wardle@theRSAgroup.com www.thersagroup.com Tel: 01707 259333 The Melon Ground, Hatfield Park, Hatfield AL9 5NB

charles.morris-denholm@rws .com www.rws.com Tel: 020 7554 5407 Fax: 020 7554 5454 Tavistock House, Tavistock Square, London WC1H 9LG

RSA is a global leader in Executive Search and Interim Management to the Life Sciences industry with offices in China, Germany, Singapore, Switzerland, UK, USA and partners in emerging markets.

We specialise in the recruitment of Executive and Non-Executive Directors and senior executives for clients operating in all sectors of the life sciences industry.

We have unrivalled expertise in Strategic & General Management Pre-Clinical R&D, Medical, Production, Distribution & Quality, Clinical & Regulatory, Sales & Marketing and Not-for-Profit.

RSA’s Talent Lifecycle Services© deliver a proven link between the Board and its HR partners. Working with clients to maximise the value and contribution of their employees and to develop their talent strategy with services optimising Talent Engagement, Assessment, Coaching and Development.

Identifying independent, experienced and authoritative Non-Executive Directors (NED) can be a major challenge to even the most well-established life sciences companies. RSA’s NED Register brings together the small, but powerful, niche community of NEDs.

timf@s-tech.co.uk www.s-tech.co.uk Tel: 01223 324333

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RWS Group - Medical Translation Division Specialising in medicine and pharmacology for more than 50 years, we serve many of the world’s leading pharmaceutical companies, CROs, medical device manufacturers and medical communications agencies. Translating from and into over 200 languages, we are equipped to handle projects of any size or complexity. ISO 9001 accredited. Translations into English from the more common languages are produced mostly in-house by a team of highly qualified, subject specialist translators, supported by RWS’ strict quality procedures. Work out of English is produced in the target country and also subject to the same rigorous quality controls.

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S-Tech Insurance Services Ltd Tim FitzJohn

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RWS Group - Medical Translation Division Charles Morris Denholm

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RSA Consulting Ltd Kay Wardle

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We have successfully supported Life Science and related industries since 1982 by arranging insurance cover for a wide range of asset, liability and financial risks. Our aim is to fully understand your business including the operating and financial exposures to achieve the widest possible protection. We are fully independent brokers with access to a broad range of UK and overseas insurers including the Lloyds market. Our clients range from Start Up Companies to International Organizations. We have a wealth of experience in supporting new ventures through their growth cycle to the conclusion of a successful trade sale exit, merger, acquisition or an IPO.

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Fax: 01223 464150

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154-156 Victoria Road, Cambridge CB4 3DZ

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SafeBox Neil Hamilton-Meikle Sales@TheSafebox.co.uk www.thesafebox.co.uk Tel: 01223 291133 Fax: 01223 291177 Scarletts Business Park, Unit 1, West Wratting, Cambridge CB21 5LS

V Safebox offers bespoke storage solutions for the lifelong management of all archival data, including physical files and all back up media. Storage areas are secure, fire rated and dehumidified to maintain the integrity of all stored material. Daily deliveries across the Eastern region, including 2 hour delivery for items required urgently, ensures easy recall of items as and when required. Back up rotations to suit your schedule and disaster recovery deliveries are available. Barcode technology guarantees the traceability of all items throughout storage areas, during transit and whilst with customers. Servicing clients across a wide range of sectors and meeting the stringent audit criteria of meditech and biotech research companies. As an ERBI Support Supplier excellent rates of storage and management are available to member organisations. To enquire about our ERBI rates or for any other queries please call 01223 291133 (Option 2) or email sales@thesafebox.co.uk

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Sagentia Ltd (UK) Candy Smellie www.sagentia.com One Broadway, 14th Floor, Cambridge, MA, United States 2142

Sagentia is a technology and product development company, working with clients from front end needs analysis to transfer to manufacture to deliver real commercial value. Established in 1986, Sagentia operates in the medical, industrial and consumer products sectors worldwide. Our uncompromising commitment to innovation has led to the launch of new technologies and products that change the basis of competition for our clients. The company also assists business leaders to create strategies for technology, innovation and growth. We can work with you wherever you are in the world. Our resources are situated in state-of-the-art facilities in Europe, the USA and China.

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Sagittarius IP

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Dr. Mark Gibson

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www.sagittariusip.com

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camb@sagittariusip.com Tel: 01223 833933 Fax: 01223 833944 3 The Mill, Copley Hill Business Park, Cambridge Road, Cambridge CB22 3GN

Sagittarius IP are a firm of Chartered and European Patent Attorneys who specialise in chemical, pharmaceutical and biotechnology subject matter. We provide the following services: - ‘invention spotting’, drafting, filing and prosecution of patent applications and representation before the UK and European Patent Offices, including oppositions and other contentious work - filing of international patent applications (PCT) and control of worldwide patent prosecution - advice on IP strategy - freedom to operate investigation - IP due diligence and - IP education Sagittarius IP was set up in 2002. On 1 April 2009, Sagittarius IP opened a Cambridge office and Mark Gibson was appointed Managing Partner of the Cambridge office. In Aug 2009, the Cambridge office relocated to larger premises in Babraham.

Sai Advantium www.saiadvantium.com Tel: 01954 714912 1 Woodland Walk, Great Cambourne, Cambridge CB23 6BE

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Sareum Ltd www.sareum.co.uk Tel: 01223 4977703 2a Langford Arch, London Road, Pampisford CB22 3FX

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Sareum is a drug discovery company, headquartered in Cambridge UK, that produces targeted small molecule therapeutics, focusing on cancer and auto-immune disease. Sareum aims to successfully deliver drug candidates for licensing to pharmaceutical and biotechnology companies at the pre-clinical or early clinical trials stage. Sareum’s Chk1 kinase cancer research programme is a joint research collaboration with The Institute of Cancer Research and Cancer Research Technology Limited. Novel chemical compounds developed by the collaboration have been shown to increase the effectiveness of current cancer therapeutics in in-vivo cancer models.

SKIL® (Sareum Kinase Inhibitor Library) is Sareum’s drug discovery technology platform that has so far produced the Company’s Aurora, VEGFR-3, ALK, FLT3 & TYK2 kinase cancer and auto-immune disease research programmes. SKIL can also generate drug research programmes against other kinase targets.

Sareum Holdings plc joined the AIM market of the London Stock Exchange in October 2004, trading under the symbol SAR. For further information, please visit www.sareum.co.uk

Sartorius Stedim UK Ltd Ben Royal ben.royal@sartorius-stedim.com www.sartorius-stedim.com Tel: 01372 737159 Fax: 01372 726171 Unit A, Longmead Business Centre, Blenheim Road, Epsom, Surrey KT19 9QQ

One Nucleus Directory 2012

Sartorius Stedim Biotech is a leading provider of cutting-edge equipment and services for the development, quality assurance and production processes of the biopharmaceutical industry. Its integrated solutions covering fermentation, filtration, purification, fluid management and lab technologies are supporting the biopharmaceutical industry around the world to develop and produce drugs safely, timely and economically. For next generation processes, Sartorius Stedim Biotech focuses on single-use technologies and value-added services to meet the rapidly changing technology requirements of the industry it serves. Strongly rooted in the scientific community and closely allied with customers and technology partners, the company is dedicated to its philosophy of “turning science into solutions” on a daily basis. Headquartered in Aubagne, France, Sartorius Stedim Biotech is listed on the Eurolist of Euronext Paris. With its own manufacturing and R&D sites in Europe, North America and Asia and a global network of sales companies, Sartorius Stedim Biotech enjoys a worldwide presence.

Schwartz MSL

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www.schwartzcomms.com

Public relations, marketing communications, strategic planning and media training

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Tel: 0208 973 2630 Fax: 0208 973 2631

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2 Sheen Road, Richmond TW9 1AE

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Science Developments Ltd

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Dr Nigel Banister

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Expertise based consultancy focused primarily on science and technology (especially life sciences). Providing business critical services in: - product development & market analysis - programme and project management - business planning - strategy - securing investment - interim management

n.banister@sciencedevelopments .co.uk www.sciencedevelopments.co.uk Tel: 07827 323 421 411 Cavalier House, 46-50 Uxbridge Road, London W5 2SS UK

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With its web-based solutions, Science Warehouse has been helping life sciences organisations take the pain out of purchasing for over a decade. Our e-procurement solution makes purchasing fast and easy for biotech staff saving time and cash whilst driving compliance and financial control. Our partnership with One Nucleus delivers a dedicated online purchasing solution for members with access to the purchasing scheme contracts through a single convenient portal. Set up is fast and simple so making savings on your purchasing can start today. Contact us today for a free online demo and to find out how you can benefit from a triple whammy of benefits: cash savings, greater productivity and spend control

info@scientagroup.com www.scientagroup.com Tel: 01223 423741

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Scienta Group Clive Edmonds

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Science Warehouse Ltd Greg Staryk-Mills greg.staryk-mills@sci-ware.com www.sci-ware.com Tel: 0333 600 6300 Fax: 0333 600 6301 Suite B2, The Half Roundhouse, Roundhouse Business Park, Wellington Road, Leeds LS12 1AH

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Scienta is a leading international provider of business innovation solutions, with particular experience in life sciences and healthcare. Strong business relationships are essential to the way we work. We help start-ups to multi-nationals to governments, tackling projects with Passion, Purpose and Pragmatism. Scienta Delivers: Enhanced competitive commercial edge Virtual, highly experienced development teams Speed to market Real performance improvement Radical cost reduction Maximising Intellectual Property value Human capital development

William James House, Cowley Road, Cambridge CB4 0WX

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Sequani LTD

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www.sequani.com/Index.htm

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Tel: 01531 634121 Fax: 01531 634753

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Bromyard Road, Ledbury HR8 1LH

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Seroba Kernel Life Sciences Ltd www.seroba-kernel.com 15 Molesworth Street, Dublin, Ireland 2

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SHW Health Ltd

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Suzanne Wait, Director

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www.shwhealth.co.uk

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Suzanne@shwhealth.co.uk

Tel: 020 7348 0931 Mob: 07740 070489

SHW Health specialises in health policy and market access. We work with pharma and biotech companies to help them gain a better understanding and better prepare for the external environment within which they operate. We provide strategic advice to help companies develop effective market access and policy engagement strategies. We work across all sectors of health and excel at bringing together stakeholders from across all sectors in health to develop powerful communications and innovative programmes that aim to improve access to treatment and improve standards of care for patients.

40 Lena Gardens, London W6 7PZ

Sigma-Aldrich www.sigma-aldrich.com Fancy Road, Poole BH12 4QH

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Simbec Research Ltd www.simbec.co.uk Tel: 01443 694309 Merthyr Tydfil Industrial Park, Cardiff Road, Merthyr Tydfil CF48 4DR

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Specialist in First-into-Human, Phase I Studies. Optimized services for faster recruitment and study completion.

Services tailored for Biotech companies requiring development of new medicinal products, particularly early (Phase I, IIa) exploratory and confirmatory clinical research. Services offered include: Phase I Safety, Tolerability and PK/PD Studies in Healthy Volunteers & Phase IIa Proof of Concept Studies in Patients. Bioanalysis, including Assay Development. Central Laboratory, Data Management and Statistics, Quality Assurance, Human Pharmacology Consulting. Niche Services include: Simbec Scintigraphy - gamma scintigraphic imaging for proof of concept of drug delivery systems SimTest - dermatology service for the development of dermatology products and transdermal drug delivery systems. All facilities on one site.

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Smerud Medical Research UK Ltd Dr Kerry Nield kerry.nield@smerud.com www.smerud.com Unit 10 & 19 Enterprise House, Manchester Science Park Ltd, Lloyd Street, North Manchester M15 6SE

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The Smerud Medical Research Group (SMERUD) is a clinical contract research organisation (CRO) operating in the European area with offices in the United Kingdom, Norway, Denmark, Sweden, Finland, Austria, Hungary, Poland and Russia. Operating since 1993, SMERUD employs approximately 80 specialists engaged in clinical research, regulatory affairs, data management, biostatistics, quality assurance, intellectual property and medical writing activities. The core competency of the organisation is clinical project management and phase I窶的II monitoring in multiple therapeutic areas (with involvement in more than 750 clinical trials and 300 regulatory projects). SMERUD is ideally sized and experienced to be a preferred partner for biotech and biopharmaceutical companies in terms of managing clinical trials in a cost-effective setting. The company can supply all operational services needed to develop a drug from first-in-man until compiling the application for marketing authorisation.

Specifically, SMERUD are unique in our considerable experience working in collaboration with SMEs to gain European funding for proof-of-concept clinical trials. As a relatively small company we have a client focused, flexible attitude, able to react quickly to changing client needs and develop innovative solutions to achieve agreed milestones.

Solvo Biotechnology

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www.solvo.com

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Gyar u. 2, Budaors, Hungary 2040

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Somaxa Ltd Julie Barnes julie.barnes@somaxa.com www.somaxa.com Tel: 07747 765069 40A Market Square, St Neots PE19 8DX

Somaxa provides services and solutions to the life science, biotechnology and healthcare sector. We offer a range of business services to support - investors requiring independent technical, scientific and commercial duediligence, - start-up companies during business planning, fund raising, early development and operations and - technology transfer offices in licensing or spin-out decisions With the advent of personalised medicine and the abundance of electronic healthcare information, Somaxa is also working with healthcare professionals, university researchers, patient groups and technology partners on the development of web based solutions for the self management of chronic diseases, the first of which is in the field of diabetes.

Nicole.Kritzinger@scambs.gov.uk www.scambs.gov.uk Tel: 01954 713454 07900 678 265 South Cambridgeshire Hall, Cambourne Business Park, Cambourne CB23 6EA

www.sehta.co.uk Tel: 0845 1308179 Fax: 0845 3451683 Suite H3 Leatherhead Enterprise Centre Randalls Road Leatherhead Surrey KT22 7RY

South Cambridgeshire District Council is a Local Authority. The District is the second largest district in Cambridgeshire. It completely surrounds Cambridge City and shares its boundaries with Huntingdonshire, Fenland and East Cambridgeshire on the northern part of its borders. In the south the district has boundaries with Bedfordshire, Hertfordshire, Essex and Suffolk. South Cambridgeshire is highly rated in independent surveys scoring highly on factors such as house prices, labour market, environment, education and health. South Cambridgeshire has played a key part in the economic growth of the Eastern Region. It successfully combines traditional industry such as agriculture and engineering with new sectors such as IT and biosciences, many of which are situated on state of the art business and science parks. It is well connected to the regional, national and international communications network, including airports, sea, rail and road transport.

adam.hajjar@spdspark.com www.swissprecisiondiagnostics .com Tel: 01234 835472 Fax: 01234 835006 Priory Business Park, Stannard Way, Bedford MK44 3UP

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SEHTA is a SEEDA-sponsored company limited by guarnatee and owned by its core members (individuals in biotechnology, diagnostics, medical devices and pharmaceuticals companies).

It provides support, signposting, lobbying and PR on behalf of its members. The mission of SEHTA is to catalyse innvoation, collaboration and international competitiveness in sector companies in the SEEDA region.SEHTA is governed by a business Board and run by a small executive team.

SEHTA is an active participant in a new EU programme ‘Biosmile’

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SPD Development Company Ltd Dr Adam Hajjar

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South East Health Technologies Alliance (SEHTA) info@sehta.co.uk

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South Cambridgeshire District Council Nicole Kritzinger

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Swiss Precision Diagnostics (SPD) is a consumer diagnostics company formed in 2007 as a 50/50 joint venture between the world leading medical diagnostics and consumer products companies Alere (formerly Inverness Medical Innovations) and Procter & Gamble. SPD is currently interested in identifying new diagnostic technologies/products to support/improve its existing products and to fill its product pipeline. Examples of technologies being sought include novel sampling systems, disease/condition biomarkers, assay reagents, assay systems, signal creation and detection systems and high sensitivity diagnostic technology platforms. SPD are looking for collaborations with both academic/research organisations and companies with relevant diagnostic technologies and/or products.

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Spectrum Regulatory Solutions Trevor Brett, Commercial Director tbrett@spectrumrs.com www.spectrumrs.com Tel: 01403 320280 Fax: 01403 320281

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Fraser House, 14 Carfax, Horsham RH12 1DZ

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Spirogen Ltd

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Marina Folarin

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www.spirogen.com

Marina.Folarin@spirogen.com

* Global Regulatory Intelligence, submissions and approvals management * Medical, Technical, Regulatory and Scientific writing and report compilation * Market Access: Health Technology Appraisal submissions and strategy, Health Economics & Outcomes Research expertise * Patient Information Leaflet readability testing and product Label management * Pharmacovigilance (PV) and Medical Information support including literature searches * Medicinal Drugs, Biopharma, Medical Devices, Drug Delivery, Nutraceuticals and Animal Health

Spirogen is a clinical phase oncology drug development company with a potent drug linker technology platform for drug conjugates.

Tel: 01983 817000

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Fax: 01983 817001

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29-39 Brunswick Square, London WC1N 1AX

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SRA Global Clinical Development www.constellagroup.com Tel: 01223 393634 20 Milton Park, Abingdon OX14 4SH

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SRG www.srg.co.uk Tel: 0207 562 1708 5th Floor, 5 Devonshire Square, London EC2M 4YD

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St Georges University of London - Centre for Enterprise & Innovation www.sgul.ac.uk Tel: 0208 266 6477 Centre for Enterprise & Innovation, Hunter Wing, Cramner Terrace, London SW17 0RE

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Having pioneered contract recruitment for the scientific community in the early 1990’s, our executive recruitment operation was established more than a decade ago and is retained by clients ranging from multi-national pharmaceutical businesses to SME and start-up organisations. Our portfolio of successfully delivered search assignments is as wide and varied as our client base and includes highly complex technical appointments as well as many confidential commercial roles, all carried out within the sensitive world of life sciences and biotechnology. Our Consultants carry out all research in-house and possess an unrivalled knowledge and expertise within this niche market, meaning all clients are assured of a truly expert consultation and search process Interim Management All our Interim executives are ‘career interims’ with impressive track records of adding value within a wide variety of organisations where specific business skills, technical expertise or change management and systems knowledge are required on a project basis. All assignments are costed on a case by case basis and are tailored to your specific requirements or recruitment budget

One Nucleus Directory 2012

St John’s Innovation Centre Ltd Miranda Edwards mewadwards@stjohns.co.uk www.stjohns.co.uk Tel: 01223 420252 Fax: 01223 420844

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St John’s Innovation Centre was established by St John’s College in 1987 to provide early stage knowledgebased companies with business advice, strategic consultancy, introductions and flexible accommodation. The Centre is located at the heart of the Greater Cambridge technology cluster, in which it plays a pivotal role.

The Centre offers firms address and serviced office accommodation to early-stage firms through a full business incubation service, incorporating a range of support, training and advisory facilities. As part of a vibrant community with an entrepreneurial spirit, tenants are start-up and early-stage companies operating in a wide range of technologies.

Cowley Road, Cambridge CB4 0WS

www.starlab.co.uk Tel: 01908 283800 Fax: 01908 283802 4 Tanners Drive, Blakelands, Milton Keynes MK14 5NA

Tel: 01223 550740 Fax: 01223 550748 Fosters Wing Anstey Hall, Maris Lane, Trumpington, Cambridge CB2 9LG

STARLAB are liquid handling specialists whose success is founded on their expertise in automated injection moulding processes for the manufacture of high-quality laboratory consumables. STARLAB’s portfolio includes its own TipOne pipette tip range and award-winning ErgoOne pipettes, as well as an extensive range of laboratory consumables, disposable gloves, benchtop equipment and sample storage solutions. STARLAB also has a competitive and successful UKAS accredited pipette calibration service for all makes and model of pipette.

As an ISO 9001 accredited company, STARLAB provides a high quality service from order through delivery to after sales care. STARLAB was one of the first UK companies in its sector to be awarded the ISO 14001 for their environmental management and award-winning plastic laboratory waste recycling service. STARLAB’s green office and warehouse policy mirrors their ‘Reuse, Refill, Recycle’ philosophy of their TipOne Pipette Tip system.

cball@supernovadiagnostics. com www.supernovadiagnostics.com Tel: 0203 170 7628 c/o Imprimatur Capital, 8 Tavistock Street, London WC2E 7PP

Stratagem Intellectual Property Management Ltd is a full-service, Cambridge UK-based, out sourced intellectual organisation and management company with global reach. Stratagem IPM Ltd fills a developing need within industry for the provision of strategic advice and intellectual property management for life science, medtech, cleantech and high technology companies. Stratagem’s qualified patent and trade mark attorneys use a commercial perspective and hands on management approach to enhance the value of IP assets.

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SuperNova is a diagnostics company with next-generation diagnostic labels and a proprietary platform for conducting point-of-use diagnostics for human and non-human health applications.

SuperNova Diagnostics® has developed a powerful proprietary label technology called AmpCrystal® and with it, a solution for providing affordable qualitative and quantitative point-of-use testing for proteins, pathogens and nucleic acids in the field.

AmpCrystals can be utilized in a wide range of diagnostic formats including lateral flow, self-contained microfluidics cartridges, microtiter, microarrays, closed systems, and research products.

SuperNova can put the lab into the palm of your hand.

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Surrey Clinical Research Centre Helen Nelson h.nelson@surrey.ac.uk www.surrey.ac.uk/clinicalresearch centre Tel: 01483 683675 The University of Surrey, Faculty of Health & Medical Sciences, Egerton Road, Guildford, Surrey GU2 7XP

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SuperNova Diagnostics Chris Ball

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Stratagem IPM Ltd www.stratagemipm.co.uk

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STARLAB (UK) Ltd infoline@starlab.co.uk

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The Surrey Clinical Research Centre is an MHRA Phase I accredited leading provider of academic and commercially sponsored early Phase trials. Particular strengths include our ability to design and execute Phase I and IIa trials in sleep, diseases of the Central Nervous System and clinical vaccinology. We have a prestigious track record of over 15 years experience and 150 clinical trials. Trials have spanned the development phases and have included both volunteer and patient populations. Other therapeutic areas in which we have worked include oncology, Parkinson’s disease, migraine, diabetes and diabetic complications, cardiovascular disease, rheumatology and respiratory medicine. We also offer a unique through-the-wall cannulation system allowing PK/ PD sampling over a 24 hour period without disturbing the sleep profile of our subjects. This enables accurate biomarker profiles to be obtained across the circadian phase without confounding values through sleep disturbance and physiological stress.

www.onenucleus.com

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Sygnature Discovery Ltd www.sygnaturechem.com Tel: 01159 415401

Founded in 2004, Sygnature CSL provides premium Med. Chem, Synthetic and Computational Chemistry Services from it’s state of the art facilities in BioCity Nottingham.

BioCity, Pennyfoot Street, Nottingham NG1 1GF

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Syne qua non

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www.synequanon.com

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Gostling House, Diss Business Park, Hopper Way, Sandy Lane, Diss IP22 4GT

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Tel: 01379 644449

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• clinical data management through optimal process design and innovative web-based data capture solutions • statistical expertise through consultative study design to study reporting across a wide range of therapeutic areas • effective project management • quality management and consultancy Built on a foundation of CDISC standardization, our flexible and site-friendly Electronic Data Capture solutions can be rapidly developed, validated and deployed – built to meet the unique requirements of the study and, coupled with our approach to standardization across all services, will deliver high quality data and in-stream reporting within a competitive pricing model.

Our project teams not only focus on the ‘what’ but also the ‘how’, proactively delivering solutions to accelerate delivery allowing our customers to focus on decision making and strategy.

Talentmark www.talentmark.com Tel: 0845 095 2626 Vintage House, 37 Albert Embankment, London SE1 7TL

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Syne qua non is one of the largest functional biometrics suppliers in Europe providing global pharma, biotech, medical device and animal health partners with innovative, cost effective development services specializing in:

Main contacts: David Nolan, CEO - Richard Adams, VP International Executive Search - Mark Johnson, Managing Consultant Quality, Regulatory & Science - Dafydd Wright, Manager, Talentmark Interims.

Talentmark is an internationally recognised executive & specialist recruitment company for the life sciences industry. Established for 40 years, Talentmark has supported organisations in building high-performance teams that have resulted in some of the most important innovations in recent years. Run by industry medical and recruitment specialists, Talentmark provides executive search, specialist recruitment and interim management solutions. With a footprint spanning more than 40 countries and the world’s leading pharmaceutical and life science organisations, Talentmark’s reach is as international as its client base. Our specialist consultants deliver solutions across all key functional areas in the biotech/pharmaceutical, device, diagnostic & service industries.

Taylor Vinters Solicitors www.taylorvinters.com Tel: 01223 225146 Merlin Place, Milton Road, Cambridge CB4 0DP

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Team Consulting Ltd Dan Flicos dan.flicos@team-consulting.com www.team-consulting.com

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Tel: 01799 532700

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Abbey Barns, Duxford Road, Ickleton, Cambridge CB10 1SX

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Fax: 01799 532701

One Nucleus Directory 2012

Working closely with our clients we apply our expertise and experience in industrial design, engineering, human factors and industrialisation to deliver medical devices from early concept through to commercial launch. As we only develop products for the medical sector, we provide our clients with deep insight into the industry. We know how to design, engineer and manufacture complex, innovative products that meet regulatory requirements. We recognise that identifying, interpreting and meeting the needs of both patients and healthcare professionals are central to successful products. And we understand that the rising cost of healthcare provision requires costeffective solutions. Above all, we believe it is the way that we work with clients that is key to our success. We pride ourselves on the quality and independence of our advice, and the strength of our relationships, which are based on integrity, honesty and trust.

Tessella plc Alan Bell Alan.Bell@tessella.com www.tessella.com Tel: 01283 559159 Fax: 01283 559151 Elopak House, Meadway Technology Park, Rutherford Close, Stevenage SG1 2EF

A Tessella solves problems and adds value to our clients’ businesses through the application of scientific methods and information technology. Innovative Informatics and Consultancy for R&D. Tessella has worked with some of the biggest names in the pharmaceutical industry for over 30 years. We help clients address a wide range of business goals, including: improving efficiency and productivity in drug discovery, delivering the business benefits of translational medicine, and faster more effective clinical trials. What makes our technology and consulting services effective is our understanding of both the science and informatics of pharmaceutical R&D, as well as unique software assets and intellectual property that reduce project risk, cost and time. With offices in Europe and North America, global companies rely on Tessella for business critical assignments.

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The Ann Hayes Consultancy Ltd Ann operates as an independent consultant, working with biotech and pharma companies and investors, to help with drug discovery programmes, particularly in the areas of CNS diseases and pain. She specializes in helping with long-term discovery strategy, portfolio management and drug discovery project management. She has also helped cofound several small companies and has sat on various boards, helping particularly to develop corporate strategy. She also sits on various advisory boards, helping particularly with scientific strategy.

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The Communications Strategy Group Inc. Edward D. Agne, President edagne@comstratgroup.com www.comstratgroup.com Tel: 01781 631 3117

The Communications Strategy Group Inc. (CSG) is a US-based consultancy providing corporate/financial communications and business development services to the life sciences, biotech and medical technology sectors; the firm assists and advises UK/EU companies seeking to expand to the US and provides corporate mentoring. CSG maintains strategic alliances with College Hill Life Sciences, London, and Cabinet Privé de Conseil s.a., Geneva.

42 Front Street, Marblehead, MA 01945 USA

richard.k@thedigitaloffice.co.uk www.thedigitaloffice.co.uk Tel: 0870 8505121 01462 810071

TDO supply to the whole market place, the complete range of Ricoh products from copiers, MFDs, printers, scanners to software and audit devices. TDO is unique in it’s relationship with Ricoh, our product manufacturers.

Ricoh, for the last 12 years, service all our machines in the field on a nationwide basis. It is an ideal relationship that ensures the best people with the maximum resource perform the most professional of service to you our clients. We provide to you a complete holistic approach to all your needs with a friendly local interface with over 30 years of experience in the industry

www.tgac.ac.uk Tel: 01603 450904

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The Genome Analysis Centre (TGAC) tgac.enquiries@bbsrc.ac.uk

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6 Brookside, Colne Way, Watford WD24 7QJ

Rachael Spooner

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The Digital Office Richard Kirby

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The Genome Analysis Centre is a genomics and bioinformatics research centre, service provider and national resource, specialising in next generation sequencing and in bioinformatics for “big data”. Our goal is to be at the forefront of data intensive science in biology, a leader in bioinformatics innovation and in the application of genome technology. We work especially in developing knowledge to underpin applications in the food, health and environment sectors.

Norwich Research Park, Colney, Norwich NR4 7UH

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The Greater Richmond Partnership Inc

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Andrew Harfoot, MA, FCIM andrew.harfoot@springboardmarketing.co.uk www.grpva.com Tel: 01732 363399 Fax: 01732 352304 c/o 1 Tonbridge Chambers, Pembury Road, Tonbridge TN9 2HZ UK

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The Institute of Cancer Research

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Dr Angela Kukula

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www.icr.ac.uk

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enterprise@icr.ac.uk

Tel: 020 7153 5186

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Fax: 020 7370 5261

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123 Old Brompton Road, London SW7 3RP

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The Greater Richmond Partnership Inc (see www.grpva.com) is the economic development body for Greater Richmond, Virginia, USA (90 miles south of Washington DC). The Partnership helps UK biotech, biomed, bio infomatics and cleantech firms grow in the USA via its Virginia BioTechnology Research Park (www.vabiotech. com) or cleantech incubator (www.domgreentech.com). GRP’s services are free and confidential. Virginia is the up and coming location for US health and life science companies and its state capital, Richmond has a major cluster of biotech and innovative care firms including Pfizer Consumer Healthcare, Owens & Minor and Boehringer Ingelheim Pharmaceuticals. Over 140 overseas companies are located in Greater Richmond primarily due to its relatively low property costs, highly skilled workforce and great quality of life. Virginia was also voted ‘Best US State for Business’ by Forbes.com for four consecutive years.

From its foundation in 1909 as a small research department of the Royal Marsden Hospital, the ICR has grown to become one of the world’s foremost independent cancer research organisations. With over 1000 researchers working across two sites in London & Surrey. Our vision: Is that people may live their lives free from the fear of cancer as a life threatening disease. Our mission: Is to relieve human suffering by pursuing excellence in the fight against cancer through: • Research into the causes, prevention, diagnosis and methods of treatment of cancer • Education and advanced training of medical and scientific staff • Treatment and care of the highest quality for cancer patients • Attraction and development of resources to the optimum effect

The Research Network Ltd Andy McElroy admin@theresearchnetwork.co.uk www.theresearchnetwork.co.uk/ Tel: 07889 818724 IPC 600 Discovery Park, Ramsgate Road, Sandwich, Kent CT13 9NJ

The Research Network is a team of consultants who, collectively, are experts in all areas of drug discovery and non-clinical development with a particular focus on the management of external research. We have many years of drug development experience having worked in a range of Pharmaceutical and Biotechnology companies, as well as for Contract Research Organisations. We have first-hand experience, proven track records and a passion for discovering and developing drugs. The Research Network provides Pharmaceutical R&D scientific consultancy, project management and due diligence services. Our experienced team has in depth expertise in Medicinal Chemistry, Biology, ADME, Safety Science, Pharmaceutical Science, CMC and API. Please contact us for guidance or to rapidly fill any gaps in your project team.

The Shredding Alliance Ltd theshreddingalliance.co.uk Tel: 07969 071725 Clay Street, Sheffield S9 2PE

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Therapure Biopharma Inc. www.therapurebio.com Tel: 1-905-286-6205 Fax: 1-905-286-6300 2585 Meadowpine Blvd, Mississauga, Canada L5N 8H9

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Thomas Eggar LLP

A

www.thomaseggar.com

B

Tel: 020 7842 3885 Fax: 020 7842 3900

C

76 Shoe Lane, London EC4A 3JB

D E

TPP Global Development Ltd

F

www.tppgd.com

G

Tel: 0131 523 1424

Drug development company based in Edinburgh looking to in-license novel IP from universities, research institutes and industry sources.

H

10 York Place, Edinburgh EH1 4EP

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Trade and Investment Queensland - London Jenny McLachlan jenny.mclachlan@trade.qld .gov.au www.investqueensland.qld.gov.au Tel: 0207 420 8772 Fax: 0207 420 8770 Queensland House, 392 Strand, London WC2R OLT UK

The Queensland Government’s Office in London helps Queensland companies expand their export opportunities into Europe and supports local companies which wish to invest in Queensland, Australia. We want to build new collaborative linkages between UK and Queensland life sciences companies and researchers. With more than 100 core biotech companies and 66 related research institutes employing more than 6,000 researchers, Queensland’s strengths are in healthcare, tropical medicine, agricultural, marine and environmental biotechnology. We are home to Professor Ian Frazer who discovered the Gardisil cervical cancer vaccine and Professor Frank Gannon of the Queensland Institute of Medical Research who both have important links to this region. We have a number of significant international companies with operations in the Life Sciences and have become the destination of choice for conduct of clinical trials in the Asia-Pacific region. Queensland has a range of exciting new technologies under development.

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TranScrip Partners

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www.transcrip.co.uk

R

400 Thames Valley Park Drive, Thames Valley Park, Reading RG6 1PT

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TTP LabTech Ltd sales@ttplabtech.com www.ttplabtech.com Tel: 01763 2626262 Fax: 01763 261964 Cambridge Road, Melbourn Science Park, Melbourn, Royston SG8 6EE

V TTP Lab Tech offers a portfolio of products that minimise assay volumes, reduce material handling costs and put the discovery tools back in the hands of the scientist. With new products in the pipeline, our strength comes from the ability to combine cutting edge science with first rate engineering, enabling us to design and develop unique novel products. Our acclaimed portfolio includes systems for Instrumentation and Automation: • High throughput, high content screening – Acumen® • High throughput and robust assay system for antibody discovery – Mirrorball® • Low-volume liquid handling for miniaturising screening assays– mosquito® HTS and mosquito® X1 • Automation of all protein crystallography techniques including LCP - mosquito® crystal and mosquito® LCP. • High-speed compound storage and retrieval – comPOUND® • Microtube transportation enabling automated sample delivery to analytical equipment from the lab workbench - LAB2LAB. Our products are backed by high-quality service, support and advice to ensure that customers receive reliable and effective solutions.

www.onenucleus.com

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Tukan Partners Ltd Dr Nigel Crockett n.crockett@tukanpartners.com www.tukanpartners.com Tel: 01223 719518 Fax: 01223 719518 166 Gilbert Road, Cambridge CB4 3PB

Tukan Partners provides hands-on, strategic and transactional commercial expertise in the pharma-biotech sector across US, Europe and Asia.

To date more than 50 major, in- and out-licensing deals and company acquisitions, totalling in excess of $1 billion have been achieved.

Tukan Partners has particular expertise in dealing with small molecules, biologicals and medical devices, in–licensing and out-licensing, preclinical and clinical assets, early-stage R&D collaborations, company financing and M&A. For further information please contact Nigel Crockett: n.crockett@tukanpartners.com

F

Ubichem Pharma Services

G

Geoff Porritt

H

www.ubichempharma.com

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gporritt@ubichempharma.com Tel: 01793 700213 07721 689326 Mayflower Close, Illatos St. 33, H-1097 Budapest Hungary

Ubiquigent www.ubiquigent.com Tel: 01223 305490 Fax: 01223 305506 The Sir James Black Centre, University of Dundee, Dow Street, Dundee DD1 5EH

Unilabs York Bioanalytical Solutions www.yorkbio.com

R

Tel: 01904 686199

S

Cedar House, Northminster Business Park, Upper Poppleton, York YO26 6QR

T

Ubichem Pharma Services provide a comprehensive range of chemistry services (on lab to pilot plant scale), from our facilities in Budapest, Hungary, to support pharmaceutical development: • Process Research and Development • cGMP API and intermediate manufacture for preclinical and clinical trials • Discovery Chemicals Catalogue – functionalised building blocks • Lead optimisation • Preparation of impurities and reference standards • Radiolabelling including cGMP radiosynthesis To support such synthetic and manufacturing programmes we offer services including: • Salt screening and crystallisation studies • Stability studies (stress tests, accelerated and long term) • Analytical method development and validation • Impurity profiling Our experienced team minimise the risks associated with scaling up medicinal chemistry routes, and have particular expertise in heterocyclic and organometallic chemistry. We are approved by the regulatory authorities for the manufacture of API from preclinical through to commercial supply. Reliability and excellent problem-solving skills make Ubichem a preferred partner for many pharmaceutical and biotech companies.

Fax: 01904 686091

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University of Essex www.essex.ac.uk

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The University of Essex, based at Wivenhoe Park, Colchester, received its Royal Charter in 1965. It is one of the UK’s leading academic institutions and has an international reputation for the quality of its research and teaching.

The University has 19 departments spanning the Humanities, Social Sciences and Science and Engineering.

There are currently around 8,800 students at the University, 25% of these within the Graduate School. The University is an international community with students from more than 125 countries. In recent assesments Essex has regularly ranked among the top 12 UK universities for the quality of its reseach and teaching, with many of its departments rated as ‘outstanding’ by international standards.

UVP Ltd (Ultra-Violet Products Ltd)

A

www.uvp.com

B

Unit 1, Trinity Hall Farm Est, Nuffield Road, Cambridge CB4 1TG

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Valirx Plc www.valirx.com 24 Greville Street, London EC1N 8SS

â&#x20AC;&#x153;ValiRx Plc is a biopharmaceutical company developing novel technologies and products in oncology therapeutics and diagnostics. The product focus is in the epigenomic analysis and treatment of cancer, but the technologies can be applied to other fields as well, such as neurology and inflammatory diseases.

The ValiRx management team comprises a mix of entrepreneurial scientists who are founders of a number of medical life sciences companies and industry-specific personnel, all with extensive experience in transferring technologies and products into the commercial arena to generate revenue and growth of shareholder value.

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Veeda Clinical Research Ltd

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www.veedacr.com Tel: 01738 850285

M

Fax: 01752 766933 Old Convent of Notre Dame, 119 Looseleigh Lane, Derriford, Plymouth PL6 5HH

N O P

Venner Shipley LLP Dr Allie Elend mail@vennershipley.co.uk www.vennershipley.co.uk Tel: 01223 437979

Venner Shipley is one of the leading firms of European patent and trade mark attorneys. We have extensive experience of filing and prosecuting patent applications at the British and European Patent Offices, including post-grant opposition and appeal proceedings, and worldwide through our network of associates overseas.

We also carry out infringement clearance work, prepare due diligence reports before launch of new products and organise litigation. We seek out the issues involved in order to understand the commercial objectives and achieve a successful, cost effective outcome.

Q R S

Fax: 01223 437980

T

Accounts Payable, 20 Little Britain, London EC1A 7DH

U

Verius Ltd Dr Stephen Bentley sbentley@verius.co.uk www.verius.co.uk Tel: 01223 402660

V Verius Limited is a member of the Product Life group of companies. At Verius we provide regulatory, pharmacovigilance and medical monitoring services for the pharmaceutical, medical device and allied industries.

Through Product Life we provide full outsourcing support for the preparation of regulatory dossiers including e CTD publication.

Fax: 01223 413689 The Jeffreys Building, St Johnâ&#x20AC;&#x2122;s Innovation Park, Cowley Road, Cambridge CB4 0WS

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www.onenucleus.com

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Vetter Pharma International GmbH info@vetter-pharma.com www.vetter-pharma.com Tel: +49 751 3700-3729 Fax: +49 7513 7007707 Oskar Gold, EywiesenstraĂ&#x;e 5 88212 Ravensburg

Vetter is an independent international specialist in the aseptic filling of syringes, cartridges and vials. The company has extensive experience with a broad array of compounds, including monoclonal antibodies, peptides, interferons and vaccines. Combining state-of-the-art technology with innovative processes, Vetter can preserve API and helps reduce time-to-market. The firm supports clients from preclinical development through global market supply. Vetter works with the worldâ&#x20AC;&#x2122;s top 10 pharmaceutical/biotech firms and emerging companies alike, and offers a more than 25-year history of quality, innovation and strategic partnership. The new Chicago facility, an expansion of Vetter Development Service, provides early-stage product support.

E F

Vivacta Ltd

G

Oliver Boucher, Chief Business Officer

H

enquiries@vivacta.com

I

Tel: 01795 419400

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www.vivacta.com/

100 Guillat Avenue, Kent Science Park, Sittingbourne ME9 8GU

Vivacta is developing a unique monitoring system to measure patient outcomes in real time at the point-of-care, whether in the hospital, in physician offices or at home. For chronic therapies, regular near-patient monitoring of drug levels and drug response allows faster therapy adjustment and longer periods within therapeutic range, leading to improved clinical and economic outcomes of interest to reimbursement agencies. The system, which uses revolutionary piezofilm technology, puts the precision and performance of lab-based analysers at the disposal of non-expert users including patients themselves. In a world where clinical and economic outcomes increasingly drive reimbursement of new therapies and affect re-appraisal of established treatments, the simpleto-use Vivacta desktop device has the potential to revolutionise the personalisation of pharmaceutical care.

Vivanova Ltd www.vivanova.co.uk/ Tel: 01628 481379 Little Court, Cromwell Gardens, Marlow SL7 1BG

O P Q

Wallder Capital Limited David Wallder

R

www.wallder.com

S

Vectis House, 7 Nightingale Lane, St Albans AL1 1DX

T

Wallder Capital Limited - Investors in early stage life science companies. Our current portfolio comprises a mixture of devices, diagnostics, imaging and medtech companies.

Tel: 01727 622855

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Wellcome Trust Sanger Institute www.sanger.ac.uk Fax: 01223 494714 Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA

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Our research at the Wellcome Trust Sanger Institute builds understanding of gene function in health and disease as well as creating resources of lasting value to biomedical research. We study diseases that have an impact on health globally by investigating genomes. Building on our past achievements and based on priorities that exploit the unique expertise of our Faculty of researchers, we will lead global efforts to understand the biology of genomes. We are convinced of the importance of making this research available and accessible for all audiences.

WISER Recycling Ltd Paul Duggan info@wisergroup.co.uk www.wisergroup.co.uk Tel: 01480 464111

A WISER Recycling Ltd is a specialist recycler of electrical equipment. We collect and process all types including lamps, fridges, televisions, IT, vending machines, electrical appliances and batteries. The Company holds certification in ISO14001, ISO9001 and OHSAS18001, and all relevant Environmental Permits. We repair and refurbish materials wherever possibe and partner several charity organisations to enable employment and providing usable recovered appliances.

B C

Suite 11 Manor Mews, Bridge Street, St Ives PE27 5UW

D

WOCP

F

www.wocp.org

G

E

Tel: 07904 354 957

H

Fax: 01733 560437 12 Grange Avenue, Cambridge PE1 4HH

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Yourway Transport

L

www.yourwaytransport.com Heathrow Corporate Park, Unit C2, Green Lane, Hounslow TW4 6ER

M N O P Q R S T U V W X Y Z www.onenucleus.com

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Advertisers Index

162

Agenta Discovery 20

KWS Bio Test Limited 28

AMRI Global UK 62

London Associates 40

Anabiotec 40

Melbourn Scientific Limited 34

ASS Asset and Systems Support Management 41

Micron Research 38

Babraham Bioscience Tech 48 & 164

MNX Midnite Express 47

Biocair International 16

Mountgrange 44

Bridge Partners 55

New England Bio Labs (UK) Limited 4

Cambridge Research Biochemicals 32

Pharmidex 59

Chesterford Research Park 19

Ploughshare Innovations L|imited 37

Cogent SSC Limited (National Skills Academy) 52

Population Genetics 39

Consultant Lindsey Foulkes 41

Potter Clarkson 58

Cytocell 8

PPMLD 58

Delta Consultants 50

Promega UK Limited 62

Distinctive Publishing 50 & 163

Q Scientific Consulting Limited 41

Europa Bioproducts Limited 54

Queen Mary Bio Enterprises Limited 34

Field Fisher Waterhouse LLP 2

Raumedic UK Limited 46

Fisher Scientific UK Limited 56

RSA Group 24

Forest Health District Council 41

RWS Group 61

Forresters 37

Science Warehouse 12

Harten Group 46

Starlab (UK) Limited 54

Health Protection Agency 61

S-Tech Insurance Servies Limited 55

Heptares Therapeutics Limited 40

Sygnature Discovery Limited 38

Jag Express 6

Team Consulting Limited 3

Kershaw Technology Services 40

Trinity College c/o Bidwells 51

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