One Nucleus 2011 by Distinctive Media Group Ltd

Directory 2011

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Contents

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About One Nucleus Welcome One Nucleus Services Member Benefits & Prices To Sponsor One Nucleus The Life Science Leadership Series Bench-to-Boardroom Dates for your Diary Purchasing Scheme Facilities Management Services Training Courses New Business Development & Training Manager Special Interest Groups European Activities Golden Triangle Partnership One Nucleus Collaborations Legal One Nucleus Corporate Sponsors One Nucleus Gold Members One Nucleus Silver Members Notes Advertisers Index

7 9 10 13 14 16 19 21 22 25 26 29 31 33 34 37 46 61 65 83 156 158

Disclaimer Published by Distinctive Publishing on behalf of One Nucleus. While every effort has been made to ensure that the information in this document is accurate at the time of going to press, no liability for damage is accepted by One Nuclues arising from any errors or omissions that may appear, however caused â&#x20AC;&#x201C; or from any editorial alterations to submitted information. The Editor reserves the right to edit or exclude entries. This publication does not include individual members. www.onenucleus.com

About One Nucleus One Nucleus is a membership organisation for international life science and healthcare companies. We are based in Cambridge and London UK, the heart of Europe’s largest life science and healthcare cluster. Vision

London and Cambridge

For One Nucleus and our members to be the top European life science and healthcare network.

One Nucleus was formed in April 2010 by the merger of two regional lifescience networks – Cambridgebased ERBI and the London Biotechnology Network (LBN). Together we form a commercial, clinical and academic powerhouse. London and Cambridge are home to at least 60% of the UK’s life science industry base, four of the UK’s five Academic Health Science Centres and three of the world’s top six universities. The merger of ERBI and LBN recognises that the CambridgeLondon network is an international life science “super cluster”.

Mission We will achieve this by maximising the global competitiveness of our members. Organisation History Established in 1997, and formerly known as ERBI, One Nucleus is a notfor-profit, membership organisation owned by its members and located in Cambridge and London – the centre of Europe’s leading life science and healthcare cluster. More than 450 members include pharmaceutical, biotech, medical device and diagnostic companies and associated technical and commercial service providers. One Nucleus’s mission is to maximise the global competitiveness of our members. For our science and technology-based members, that means being global leaders in the research, development and commercialisation of healthcare innovations that radically improve the quality of people’s lives around the world. For our business and professional services members, it means delivering exceptional services that significantly enhance the business performance of their clients.

The merger, driven by requests from ERBI and LBN members, resulting in significant member benefits including: l A large pool of companies to support business-to-business interaction l Membership of a cluster of international size, relevance and visibility l One membership providing discounted entry to events in London and Cambridge l Economies of scale supporting our group purchasing scheme l An expanded training programme focused on the needs of members

www.onenucleus.com

Welcome Welcome to the One Nucleus Company Directory for 2011. I am delighted that One Nucleus continues to be the largest life science and healthcare organisation in Europe, with over 450 members. This directory profiles all our members. Company details have been supplied to us by the companies featured. I hope these will help you to identify old friends and also new potential partners, customers and suppliers from the One Nucleus family. We operate two levels of membership – Gold and Silver. Please see inside for details of the benefits of membership if you haven’t yet joined us. We have had some exciting developments in the company recently – not least the formation of our new company – One Nucleus – the result of a merger of ERBI with the London Biotechnology Network.

If you are interested in finding out more about us and how we can help you to maximise your growth and competitiveness, do contact me or a member of the One Nucleus team and we will be delighted to help. Times do not get any easier for the life science and healthcare sector or the wider UK economy. I hope that One Nucleus support has been worthwhile for our members and we very much look forward to continuing to serve you and new members into 2011.

www.onenucleus.com

One Nucleus Services Conferences and Networking Life Science Leadership Series (Cambridge) Responding to the changing needs of our members and the life science landscape, One Nucleus is delighted to announce the evolution of its traditional Cambridge BioPartnering Exchange to bring you the next generation in life science conferences. The Cambridge Life Science Leadership Series will deliver a cost-effective fora to showcase what is driving commercial deals, value creation, platform technologies and Government support in specific focused areas. These will be: l l l

12 May 2011 - Oncology - Clare College 29 September 2011 - Healthcare Technologies - Clare College 26 January 2012 - CNS & Ageing - Clare College

Bench-to-Boardroom (Cambridge) 8 March 2011 - Newmarket Racecourse Bench-to-Boardroom is our life science and healthcare supplier exhibition in Cambridge which also includes round-table workshops on a range of commercial and technical issues to provide education and networking opportunities. The exhibition sells out each year and provides delegates with an opportunity to source new suppliers and service providers as well as learn from the experts supporting the life science and healthcare industry. This intensive one day networking event attracts more than 500 delegates.

Genesis Conference (London) 1 December 2011 - Queen Elizabeth II Conference Centre Genesis has been running as London’s international life science networking conference since 2000. The event is a showcase for UK life science, aiming to assist emerging life science companies in meeting investors and technology partners. It also provides a stimulating forum for debate, led by a selection of high level keynote speakers and for the first time in 2010 we included informal partnering – which was a great success with over 500 ‘speed’ meetings having taken place. The first class exhibition features more than 60 UK and international exhibitors, making Genesis an international business hub for the life science sector. Cambridge Network Meetings & London BioWednesdays Network Meetings bring together our broad membership for networking and collaboration in an informal setting. Meetings are usually held in the afternoon or evening, starting with presentations on a relevant and current topic and ending with a networking session. We run at least 15 network meetings each year with attendance ranges between 50 and 150 delegates. Gold and Silver Members are entitled to free entry for up to three delegates. Additional member delegates are charged at a discounted rate. www.onenucleus.com/events

One Nucleus Directory 2011

Purchasing Scheme

Training Programme

Special Interest Groups (SIGs)

The One Nucleus Purchasing Scheme was set up to deliver low cost purchasing based on the combined spend of our members. The scheme saves One Nucleus members £2.5 million per annum. By joining together in the scheme, small businesses enjoy the same purchasing influence as larger companies and we are able to negotiate excellent prices and substantial savings in a number of product areas, including lab consumables, stationery and courier services.

One Nucleus recognises that a company’s employees are its most valuable asset. Many rapidly growing companies overlook the need for ongoing training of their staff. One Nucleus has developed a portfolio of training courses designed to help life science and healthcare companies build an experienced and cohesive workforce. Employees should be able to contribute far beyond their technical capacity to enhance company growth and success as well as developing their personal skills.

We run a range of special interest groups for our Gold Members. These include - Purchasing, Human Resources, Facilities, Security & Business Risk, Alliance and Project Management and Health & Safety. We are planning a Buisness Development SIG for 2011.

In addition to the Support Supply Agreements (SSAs) that are available to all One Nucleus members, Gold Members also have exclusive access to our Preferred Supply Agreements (PSAs) – tendered agreements with various suppliers.

We have developed a range of tailored training courses based on the needs of our member companies. We are constantly developing courses on new subjects as our members’ needs change.

Our suppliers are selected based on their ability to offer: l l l l l l

Substantial discounts (up to 50% off catalogue prices) No minimum order requirements No delivery or handling charges Guide payment terms of 30 days with the option of monthly consolidated invoicing Delivery next day if in stock Volume rebates for companies exceeding annual turnover targets

Courses are available to members and Non-Members. Non-Members pay a commercial list price rate, while Silver Members receive a discount from the list price and Gold Members receive increased discounts off the list price plus priority booking.

The aim of these meetings is to provide a platform for people doing similar jobs in different companies to get together informally and discuss the issues that affect their working lives. Meetings are typically held three or four times a year, starting with a presentation on a topic nominated by the SIG, followed by discussion and lunch. One Nucleus reserves the right to exclude individual Gold Members from individual SIGs where we consider there to be a conflict of interests. *

Savings vary from company to company, but on average our members save over 35% on their annual spend.

www.onenucleus.com

Contract Biopharmaceutical Manufacture of monoclonal antibodies and recombinant proteins

Alpha Biologics - the protein people

Choose from our services: cell line generation, stability and banking services upstream & downstream process development process optimisation and scale-up technology transfer and cGMP manufacture

Benefits: choose from a wide range of service options bioreactors from 10 to 500 litres to suit need and budget flexible, multi-track processes to minimise time and cost full suite of back-up services: QC analysis & control, QA and regulatory affairs, cell line and product characterisation

Alpha Biologics Babraham Research Park Babraham Cambridge CB22 3AT United Kingdom : +44 (0) 1223 496 070 T F: +44 (0) 1223 496 071 E: info@alphabiologics.com

www.alphabiologics.com

We offer two levels of membership – Gold and Silver. Silver Members receive entry-level benefits. Gold Members enjoy an enhanced range of exclusive services and benefits. The following ‘benefits table’ compares the services available to Gold Members and Silver Members.

Member Benefits & Prices BENEFIT

NON-MEMBER

GOLD MEMBER

SILVER MEMBER

Profile in One Nucleus website member directory

Post news on the One Nucleus Website

Post events on the One Nucleus website

Post jobs on the One Nucleus website

Cambridge Network Meetings £150 + VAT per per delegate

3 free delegates £40 + VAT additional

One free delegate £40 + VAT additional

London BioWednesday Meetings £150 + VAT per per delegate

3 free delegates £40 + VAT additional

One free delegate £40 + VAT additional

£420 + VAT

£175 + VAT

£295 + VAT

Genesis Conference

List price

Discount

Bench-to-Boardroom Networking Exhibition

List price

Discount

Full discount plus priority booking

Partial discount

Life Science Leadership Series

One Nucleus training List price Discounts under Support Supply Agreements (SSAs)

Discounts under Preferred Supply Agreements

Participation in Special Interest Groups

COMPANY SIZE

GOLD MEMBER

SILVER MEMBER

Academic, individual

£150 + VAT

N/A

Start-up, first year only, <10 employees

£220 + VAT

£900 + VAT

Small, <20 employees

£305 + VAT

£1,390 + VAT

Medium, 21-50 employees

£400 + VAT

£2,350 + VAT

Large, 51-150 employees

£500 + VAT

£3,500 + VAT

Extra large, >150 employees

£600 + VAT

£5,000 + VAT

All prices current to March 2011 www.onenucleus.com

To Sponsor One Nucleus “We at One Nucleus appreciate the need to ensure that sponsorship delivers value for money to each individual sponsor. Moreover we want to work with sponsors who can add real value to our core activities.” - Harriet Fear CEO

In addition to membership, you can become involved with One Nucleus either as a Corporate Sponsor or by sponsoring one of our events. One Nucleus has a successful track record in providing a platform for people from all parts of the life science and healthcare community to meet and interact. We achieve this through hosting a wide range of events in Cambridge and London, exhibiting at national and international events, hosting delegations from overseas, publishing newsletters and maintaining a content-rich website.

One Nucleus sponsorship will enable you to:

Promote your company via One Nucleus not just to the Cambridge and London community, but to the global industry

Our mailing list currently includes over 8,000 people working in the global life science and healthcare sector.

Corporate Sponsorship attracts all Gold Member benefits plus one complimentary ticket to each of the One Nucleus Leadership series conferences.

1. Raise your company profile in one of the top cluster communities in the world 2. Align your organisation with the leading life science and healthcare network in Europe

If you would like to support One Nucleus as a Corporate Sponsor please contact harriet@onenucleus.com

SPONSORSHIP

BENEFIT TO YOUR COMPANY

One Nucleus Correspondence

Your company name on the One Nucleus letterhead

Website

Your logo featured on the home page of the One Nucleus website

Your company name listed on the corporate sponsors’ page of the One Nucleus website

One Nucleus Promotional Materials

Your logo on One Nucleus’s standard PowerPoint Presentation about the life science and healthcare sectors in the East of England

Your logo on relevant promotional flyers

One Nucleus logo on your communications as appropriate

First refusal on further sponsorship opportunities such as Network Meetings

Newsletter

Your name on One Nucleus’s hard-copy newsletters – four per annum

Inclusion of one of your flyers in one hard-copy newsletter a year

Events and Conferences

Distribution of your literature by One Nucleus at the national and international events where One Nucleus is exhibiting e.g. Genesis and MOU partner events

One Nucleus Directory 2011

Current Corporate Sponsors

CORPORATE PATRON

www.onenucleus.com

The Life Science Leadership Series Responding to the changing needs of our members and the life science landscape, One Nucleus is delighted to announce the evolution of its traditional Cambridge BioPartnering Exchange to bring you the next generation in life science conferences.

Are you in focus? l Focus by therapy or health technology area mapping, onto the way commercial deals are sought and evaluated l Focus brings seniority of delegate l Focus brings high quality key opinion leader debate

Do you have an investment sat nav? l Assembling deal flow leaders from the Bio-Pharma, healthcare and investment community l Successful investment relies upon understanding the future clinical, regulatory and business needs l Debate will identify the future opportunities for entrepreneurs, investors and technology development organisations

The Cambridge Life Science Leadership Series will deliver a cost-effective forum to showcase what is driving commercial deals, value creation, platform technologies and Government support in your area of interest.

12 May 2011 - Oncology - Clare College 29 September 2011 - Healthcare Technologies - Clare College 26 January 2012 - CNS & Ageing - Clare College Conference Agenda Framework:

Partnering, & Publication & Profile

l Plenary session of KOLs

l Online 1-2-1 business forum

l Successful deal case studies

l Presentation opportunities

l Emerging company showcase

l Limited exhibition and sponsorship opportunities

l Platform technology exemplars

One Nucleus Directory 2011

l Legacy report to showcase relevant members

The highest quality service in custom-made peptides and antibodies Celebrating 30 years in 2010, as the world’s second-oldest peptide manufacturer, Cambridge Research Biochemicals (CRB) combines a progressive scientific approach with a thorough commercial instinct. Customers are at the heart of our business. Specialising in the chemical synthesis of peptides and polyclonal antibodies, we provide a highly focused, highly personal level of service. With long-standing relations with some of the world’s largest pharmaceutical companies, we provide individual, not off-the-shelf solutions.

Jointly owned by Emily Humphrys and Alison White – scientists with commercial backgrounds – our company is keen to build on its success and experience with new strategic partnerships. We look for small, specialist biochemical businesses and research institutes whose work complements ours and whom we can help grow and expand.

What we offer: Peptide synthesis

Fluorescent dyes

Tailored products and services

Antibody production

PNA synthesis

Partnering opportunities

Dye and Radio-labelling

Increased market exposure

High standards Outstanding customer service Operational excellence

CRB proudly sponsors:

Cambridge Research Biochemicals

10 Belasis Court, Belasis Hall Technology Park, Billingham, Cleveland TS23 4AZ United Kingdom www.crbdiscovery.com T +44 (0)1642 567180 F +44 (0)1642 567181 E enquiries@crbdiscovery.com

PARTNER

Babraham BIOSCIENCE TECHNOLOGIES

www.path.cam.ac.uk/campod

Now you really DO have a choice! For the last 10 years, JAG EXPRESS has been expertly looking after the express courier and logistics requirements of Companies and individuals within the Bioresearch sector in and around Cambridge. We have seen customers go from the initial research phase through to full production and beyond, with them calling on our differing services as their needs changed. For much of this time, we have been frustrated seeing how other Courier Companies overcharge and overcomplicate the issue of handling Hazardous, Biohazard, Medical & Dry Ice shipments …

We have our own fully trained IATA Approved Dangerous Goods Specialist on site, meaning we can cut out the other middle men and offer you totally unbiased advice and practical help in moving hazardous and medical materials anywhere in the world … and we believe our in house systems and dedication to customer service mean that we can simplify the process for you and reduce your costs. As an example – one of our existing customers is saving over £400 on each Dry Ice shipment they send abroad with us compared to their previous supplier!

But now you really do have a choice …

So whether you’re new to shipping either standard or hazardous materials, or experienced and just want to check out your options – why not contact us and try us out?

Customer feedback …

Our services include …

“What a pleasure to deal with a supplier who not only seems to care about our goods but actually shows an interest in our business ... you make us feel as if we are your best customer.”

• • • • • • • • •

“Fantastic service! Jag has really found a way to ship our Dry Ice shipments around the world simply and on time ... and is saving us hundreds of pounds per shipment compared to our old supplier ...” “... your software is saving me several minutes on each shipment I send. It may not sound like a lot, but if I’m sending 10 or more in a single day the time saving really mounts up!” “We were told by xxx that our shipment requirement was impossible. One quick call to Jag and it became not only possible, but achievable and under budget” “It’s great to have found a local supplier that gives the big boys a real run for their money ...”

Local, UK & European Same Day Courier UK Overnight Packets, Parcels and Freight International Express Packets and Parcels, Logistics and Freight Packaging Exhibitions Pick & Pack Imports Consultation Hazardous, Medical & Dry Ice Shipments

JAG EXPRESS LTD 36 Clifton Road Cambridge CB1 7ED Tel: 01223 242250 Fax: 01223 242260 Email: ops@jagexpress.co.uk www.jagexpress.co.uk

Bench-to-Boardroom Bench-to-Boardroom is our networking exhibition with workshops for the life science and healthcare industry, brought to you by One Nucleus, the Business Catalyst for Life Sciences.

The intensive one-day event combines a supplier exhibition with round table workshops and keynote presentations from high-profile speakers. The informal nature of the event is designed to facilitate networking and information sharing to promote business-to-business interactions. For 2011 the event will be held on 8 March at an exciting new venue – Newmarket Racecourse – to build on the success of previous years. At our last event in October 2009, more than 500 delegates and 60 exhibiting companies took part. Our exhibition covers a wide range of suppliers to the industry, from equipment suppliers to providers of technical and commercial services, providing visitors with a key opportunity to source new suppliers and learn from the experts supporting the industry.

Keynote presentations from thought leaders will stimulate ideas and discussion. Round-table workshops are designed as a forum to discuss and share ideas about key issues affecting the industry. Who should attend? Research and operational staff working within life science, healthcare and technology companies. Bench-to-Boardroom provides an excellent opportunity to meet new business partners, learn something new and network with experts in the field. Whether you come to hear our keynote speakers, source new suppliers, meet existing suppliers, take part in round table workshops, or simply network, Bench-to-Boardroom is for you. Attendance is free for One Nucleus Gold Members, £50 for Silver Members and £75 for Non-Members.

www.onenucleus.com

Dates for your Diary 2011/12 dates:

MAR

Bench-to-Boardroom 8 March

FEB

Cambridge Network Meeting 3 February (TBC)

MAR

Cambridge Network Meeting 31 March

APR

London BioWednesday 6 April

MAY

Life Science Leadership Series - Oncology 12 May

JUN

London BioWednesday Summer Social 16 June

08 03 31 06 12 16

JUL

Cambridge Summer Social 6 July

SEP

Life Science LeadershipSeries - Healthcare Technologies 29 September

OCT

London BioWednesday 5 October

NOV

Cambridge Network Meeting 3 November

DEC

Genesis 1 December

JAN

Life Science Leadership Series â&#x20AC;&#x201C; CNS & Ageing 26 January 2012

www.onenucleus.com

Purchasing Scheme The One Nucleus Purchasing Scheme has been running for over 10 years with an annual turnover exceeding ÂŁ6 million, with more than 70 Gold Members and is the longest running purchasing consortium of its kind. The purchasing scheme is directed by an Operations Steering Group comprising of Gold Member companies and delivers substantial cost savings to Gold Members with the vast majority of member companies saving more than their annual subscription to One Nucleus. One Nucleus currently has 8 Preferred Supplier Agreements (PSAs) in place which undergo a rigorous tender process and are selected, not by One Nucleus but by the Steering Group. The scheme is only available to One Nucleus Gold Members.

One Nucleus Directory 2011

They are: l l l l l l l l

Fisher Scientific - Providing laboratory consumables, laboratory chemicals and low value apparatus Sigma-Aldrich - Providing molecular biology, cell biology and cell culture products STARLAB - Providing pipette maintenance and calibration services Air Liquide - Providing laboratory gases and dry ice GE Healthcare - Providing servicing and maintenance of laboratory equipment Harts Office Supplies - Providing stationery, office goods, IT consumables and office furniture Deliver Plus - Providing courier services including dangerous goods and items on dry-ice. BOC â&#x20AC;&#x201C; Providing Liquid Nitrogen Services.

Benefits of PSAs: l l l l l

No minimum order requirements No delivery or handling charges 30 day payment terms Option for monthly consolidated invoicing Internet ordering with additional discounts

One Nucleus can perform a cost-benefit analysis for Silver Members considering of upgrading or companies wanting to become Gold Members. Please contact Richard Dickinson on 01223 896453 or richard@onenucleus. com.

Current SSA’s One Nucleus also offers Support Supply Agreements (SSAs) which are available to all members. If sufficient interest is generated by an SSA, then the contract will be considered for upgrading to PSA status (following the tender process).

l Pressplan Travel - Discounted business travel solutions l Grundon Waste Management Ltd Specialist waste management services l The Royal Cambridge Hotel - Discounted room rates l Science Warehouse - Spend management in a dedicated webbased procurement solution l The Digital Office - A wide range of digital office equipment and software solutions l Core Cambridge - “Deskcoach” a unique scheme to treat postural pain and is the only company in the UK to provide access to techniques used by top athletes to avoid or recover rapidly from injuries, most of which are due to poor posture l S-Tech Insurance - Commercial Insurance, Credit Insurance, Personnel Insurance, Employee Benefits, Private Medical Insurance and Financial Services to companies and their employees l Pro-Active Security Solutions Security screening and intelligence l Charles Kendall BioLogistic Exhibition services l Thomson Pharma database - Comprehensive global pharmaceutical information solution that covers the entire drug discovery and development pipeline l The Safe Box - Document and data storage l World Courier - BioPharm and Clinical Trial logistics l Adelphi Healthcare Packaging Healthcare packaging l Arkadin - Audio and web conferencing

l CLS Communication - Multilingual communication l Daisy - Telecommunications l ARCO - Safety and maintenance supplies l Fire Safety Services – Fire safety services l Cambridge Car & Van Rental – Car and van rental l Websters - Tax, Legal, Accountancy & Financial Planning services l College Hill Life Sciences – PR and Communication services l Novus Environmental – Specialist waste management services l RWM Data Management - Data Management services l Forecast Flow - Business Cashflow Forecasting l KISS Communications - Integrated Marketing services l First Ascent - Leadership and Management Development services l Doubletree by Hilton Cambridge Hotel & Conference Accommodation l Softwerx - IT Support, Hardware and Software services l Gram UK Ltd – Fridges and Freezers l Eagle Genomics - Genomic Data Management and Integration l Labute Group Ltd – Printing services l Cambridge BioFreeze Ltd Biobanking and Disaster Recovery for Low Temperature Samples l Quality Care Cleaning Services Commercial Cleaning services l Biopharma Technology Ltd - Freeze Drying Services and Training l SRG – Recruitment l Amphora Research Systems Electronic Laboratory Note Books

www.onenucleus.com

“NVQs have been an excellent training tool to raise the standard of everyone’s competence.” Bayer CropScience “Returns on training have been astounding with financial benefits exceeding £5M since 2001.” Warwick Chemicals

Enhancing skills through qualifications PAA\VQ-SET is an independent specialist Awarding Organisation recognised and regulated by UK Qualification Regulators. We offer over 100 unique and specialised nationally recognised qualifications in a wide range of areas including: n n n n n n n

Business-Improvement Techniques Chemical, Pharmaceutical and Petro-Chemical Engineering Laboratory and Associated Technical Activities Laboratory Science Process Manufacturing Scientific Manufacture

Our professional and experienced team provide ongoing support to our network of Centres. We work with more than 200 Centres based throughout the UK and internationally. PAA\VQ-SET Approved Centres include: Bayer CropScience, Brunner Mond, GlaxoSmithKline, Novartis Vaccines, Royal Society of Chemistry, Shell UK Oil Products Ltd, Solvay Interox, Trafford College, TTE Training Ltd, Warwick Chemicals.

Want to Find Out More? Contact Us Today Tel: 01543 254223 Email: info@paa-uk.org Web: www.paa-uk.org

Facilities Management Services Facilities management can be a real problem for small technology companies with exacting demands for laboratory, workshop and office space. Do you know that One Nucleus provides a range of Facilities Management Services to help our member companies to expand or relocate? We can provide project management for office and laboratory fit-outs (no job too small) and can help with laboratory service contracts, maintenance contracts, cleaning contracts, utility bills, insurance, purchasing and budgeting. As with all One Nucleus services, these are provided at discounted rates to members. Our Facilities Management Services and Purchasing Scheme are managed by Richard Dickinson, One Nucleus’s Director of Specialist Services, who has more than 10 years experience in laboratory and facilities management. Before One Nucleus he worked for Cantab Pharmaceuticals and Astex Therapeutics, where he project managed the fit-out of a 45,000 sq ft building, plus another of 36,000 sq ft. In addition to procurement of lab and office equipment and furniture, he managed the move from one building to another over a weekend. Richard has extensive local contacts in the Cambridge area and is also NEBOSH certified in Health and Safety. Richard can provide help by phone or email as well as providing full onsite consultancy. One Nucleus also provides

Health and Safety consultancy to members at a discounted rate. We provide support for health and safety policy development, training and audits. Sara Cooper, Director of SJC Safety Training and Consulting and former Director of Health and Safety at the University of Cambridge, is One Nucleus’s principal health and safety consultant. She has worked on expert committees in the UK and for the EC, and for international clients setting up specialist facilities, including the design and operation of safety-critical laboratories. During 18 years as a safety professional she has focused on safety auditing, management training and promoting safety at director level. She is a Fellow of IOSH, a Chartered Safety Practitioner, a Member of the Royal Society of Chemistry and a Member of ISTR. Please contact Richard Dickinson on 01223 896453 or richard@onenucleus. com if you have any questions about One Nucleus’s Facilities Management or Health and Safety Services.

www.onenucleus.com

Training Courses One Nucleus is dedicated to providing bespoke training and support to the Lifescience and Healthcare Industry, through a comprehensive portfolio of industryspecific short courses.

How it all began In 2002 a group of biotech companies in Cambridge asked One Nucleus to develop training courses that addressed the needs of their employees in the drug discovery and development sector. After interviewing around 70 companies to ascertain their training requirements, it was evident that new recruits to the industry wanted to gain a complete overview of the entire drug discovery and development process, from early stage research to the marketing of approved drugs. So we set out about developing our first course “Introduction to Drug Development”. Since then we have significantly expanded our portfolio of courses for the Lifescience & Healthcare Industry, working alongside our members to develop courses which address the current skills gaps within their organisations.

Each of our courses is designed by industry experts, and piloted to small classes, before being offered to all relevant companies. Feedback from the hundreds of delegates who have attended our courses has, without exception, been positive. Based on this success we are now delivering these bespoke courses to Lifescience & Healthcare companies and service providers throughout the UK and Europe. Our current range of courses includes: l Small Molecule Drug Discovery – a biological perspective l Introduction to Drug Development l Introduction to Management l Health and Safety for Representatives and Managers l Laboratory Health and Safety l Commercial Awareness - From Bench to Balance Sheet l Scientific Presentation Skills l Project Management l Directing Safely (IOSH accredited) l The Safe Use & Management of Laboratory Gases l Cultural Awareness Workshops l Biosafety Practitioner Level 1 (Foundation ISTR accredited) l Mail Handling & Security in the Workplace l Managing Safely (IOSH accredited) All courses can be delivered in-house, tailored and/or combined to create a bespoke training package which meets the exact needs of your organisation. Member organisations who have incorporated some of our courses into their induction programmes include: l MedImmune l Institute of Cancer Research l Amgen

One Nucleus Directory 2011

Organisations who have participated in One Nucleus Training Programmes include:

l l l l l l l l l l l l l l l l l l l l l l

Abcam plc Arecor Limited Arla Foods Limited UK Astex Therapeutics Ltd Cambridge Biotechnology Ltd (CBT) Cantab Biopharmaceuticals Ltd Cellzome Limited Crescendo Biologics Cytocell Technologies Eagle Genomics Ltd Heptares Therapeutics Horizon Discovery Services IDEC Inc. Illumina Cambridge Ltd Isogenica Ltd KuDOS Pharmaceuticals Ltd KWS UK Ltd Lab21 Lonza Biologics Plc Melbourn Scientific Ltd MRC Centre MRC Technology

l l l l l l l l l l l l l l l l l l l l

One Nucleus Origin Sciences Limited Oxford Nanopore Technologies Ltd PA Consulting Group Pathology Diagnostics Ltd Pfizer Regenerative Medicine PiR Interims Limited Polytherics Population Genetics Technologies Ltd Quotient Bioresearch Ltd Remtec Search & Selection Ltd Selcia Limited Sphere Medical Ltd Synairgen Research Ltd Takeda Cambridge Limited Thermo Fisher Scientific University of Birmingham University of Brighton and Sussex Medical School Wellcome Trust Sanger Institute Xention Limited

www.onenucleus.com

New Business Development and Training Manager Philip Kendall is the newest member of the One Nucleus team, joining us from the BIA and formerly UK Trade & Investment. His focus in 2011 will primarily be the following: l To undertake a detailed training needs analysis of our members and enhance the training portfolio as appropriate l To input to national and regional government policy relating to the skills and training agenda l To work closely with other members of the One Nucleus team on continuing to enhance the member offer â&#x20AC;&#x201C; with a particular focus on the training and business development needs of our members

If your company has an unmet training need, please contact Philip and he will identify relevant courses from the One Nucleus portfolio, or consider other bespoke possibilities to help you meet that need. There may even be training grants available for your company from the European Social Fund, through the Beyond 2010 project, or other regional sources. If you have any questions about Training or Business Development please contact Philip on 01223 896457 or philip@onenucleus.com

www.onenucleus.com

Special Interest Groups Special Interest Groups (SIG’s) are typically run four times a year and are only open to Gold Members.

HR - The HR Special Interest Group has been established for a number of years. The group meet regularly throughout the year for a series of workshops and seminars on HR hot topics. Facilities - These meetings are relevant to people who are responsible for the day to day running of their company’s facilities. Discussions focus on key areas of facilities management such as equipment management and bench marking the cost of running labs and offices. Purchasing - This SIG supports One Nucleus’s well-established purchasing scheme, where Gold Member companies gain significant discounts on items such as laboratory consumables and office supplies and services such as pipette maintenance. Security & Business Risk - Special Interest Group that focus’ on Risk Management & Business

Health & Safety - The aim of the Health & Safety SIG is to provide an area of communication for Health & Safety Managers. These meetings were develop at the request of health & safety managers who wished to meet with their industry peers, topics covered - stress management, waste reduction, legislative updates and the overview of the challenges facing health and safety managers. Alliance and Project Management - This group operates for people who have a role in running projects within companies, and/or across alliance partner companies. Our purpose is to provide support and networking opportunities - particularly to people who may not have not had much formal training or many years experience in cross-functional working and project management.

The aim of this SIG is to bring together individuals responsible for both security and operational management. Recent talks have covered industrial espionage, security contractor management and managing risk in a laboratory setting.

www.onenucleus.com

ChELSI Institute: Engineering with Molecules • Interdisciplinary research between Chemical Engineering and the Life Sciences • New purpose built laboratory space & state of the art mass spectrometry facilities • Funded by £ 4.3M EPSRC Science and Innovation Award in 2006 Cancer Research

Environment

Energy

Regenerative medicine

Proteomics

Our services include research, consultancy, technical training and sample testing.

Medical Research

Metabolomics

The Polymer Centre represents the University of Sheffield’s 40+ research groups in polymer science and engineering. Our business team serves as the interface between academic research and the commercial world.

Engineering

Computational Science

The University of Sheffield works to improve the world by seeking to understand it.

Systems Biology

For further information contact Prof Phillip Wright p.c.wright@shefffield.ac.uk, phone 0114 222 7557

For further information and enquiries, please contact Joe Gaunt on +44 (0)114 2229440 or visit our website www.polymercentre.org.uk

Sheffield Synthesis Solutions.

Expertise In Chemical Synthesis S3 represents four research groups in the Department of Chemistry, who specialise in synthetic chemistry. The S3 team have expertise in the development and application of new synthetic methodology and have experience of delivering training and research projects to industry.

S3 offers: Consultancy Research – from short 3 month to 3 year multinational projects. Our business team can offer help and advice in sourcing funding for these projects. l Training l Test and Analysis service l

If you like more information on what S3 has to offer please contact Jenny Morton on (0)114 222 9563, or visit our website at www.sheffield-synthesis.org.uk

Serving the bioscience sector Bioserv is a specialist service company with expertise in the production and processing of bio-molecules. Using state-of-the-art technology we provide products encompassing key research areas such as immunology, proteomics and cell and molecular biology. Projects undertaken include: l Monoclonal

and polyclonal antibody development l Expression

of recombinant proteins in prokaryotic and mammalian culture systems l Generation

of serum and protein free suspension cell lines and subsequent scale-up l Downstream

processing and associated protein chemistry analytics and document support

W: www.bioservuk.co.uk E: enquiries@bioservuk.co.uk T:(+44)1142227480

One Nucleus Directory 2011

European Activities One Nucleus’s mission is to maximise the global growth and competitiveness of our members. One of the key strands of our strategy is to internationalise our activities and encourage our members to take advantage of platforms and initiatives we work on in this regard. We recognise that for UK companies to be strong, they need to have access to and relations with other exceptional global companies. The sector is global and the success of it hangs on us working in partnership for mutual benefit. With this in mind, One Nucleus plays an important role as partner in two ECfunded projects: India 1. The European Business and Technology Centre (EBTC) aims at further developing the EU-India trade and business relations. The project is coordinated by Eurochambre, and includes One Nucleus and 15 other European partners. The Centre’s activities are organised in four key sectors: Environment, Energy, Transport and Biotechnology. The aim of the project is to create a Centre which will become a point of reference for European companies wanting to enter the Indian market. The Centre is planning to achieve this by acting as a multiplier and facilitator; increasing the understanding among EU SMEs and researchers about the opportunities offered by India; and provide an active link between policy makers and private bodies. Europe 2. ABCEurope is an intercluster project coordinated by the Milan Innovhub (Milan Chamber of Commerce) and funded by Europe Innova. It brings together 13 biotechnology clusters across Europe including One Nucleus as a leading partner.

The overall objective of the project is very tangible: raising the standard of services to SMEs and defragmenting the delivery of such services to SMEs across Europe. Examples of the activities that will be targeted by the project include entrepreneurship support in the form of self assessment tools and boot camps, facilitation of access to research infrastructures, centralisation of intellectual property support mechanisms, a non-executive directors database and technology showcases. Within the framework of this project, One Nucleus will launch the following activities during 2011: l The ABCEurope Bio-entrepreneurs’ boot camp: a short but intense training course covering all the aspect of launching a biotechnology start-up from a practical perspective. It will feature speakers from academia and industry as well as successful entrepreneurs, and will allow plenty of space for networking opportunities l A European Biotechnology Showcase: the objective of this event is to facilitate industry / academia interaction and to promote European research in biotechnologies at an international level. One Nucleus aims to run this event alongside an established international technology transfer conference. l The European Biotechnology Non Executive Directors (NEDs) group: a virtual group of experienced European NEDs available to support biotech start-ups both in the UK and the rest of Europe. If you are interested in receiving more information about the above projects and activities please contact One Nucleus’s European Project Manager, Gigi Møller (01223 896 458 or gigi@ onenucleus.com).

www.onenucleus.com

Golden Triangle Partnership The Golden Triangle Partnership is an informal collaboration between One Nucleus and the Oxfordshire Bioscience Network (OBN) – the combination of these two groups representing Europe’s strongest region in life sciences and healthcare. The aim of the partnership is to provide members with access to potential partners and investors from other global centres of excellence.

One Nucleus members have expressed a desire for us to develop strategic partnerships with other leading clusters. With this in mind, Harriet Fear, One Nucleus CEO worked closely in 2009 with Tony Jones of (then) LBN and Jon Rees of OBN to open doors with leading US clusters. Plans progressed at the 2009 BIO conference in Atlanta when a meeting between the GTP and the Massachusetts Biotechnology Council (MassBio) discussed the concept of formalising a relationship between them for the benefit of all members. In October 2009 the GTP signed its first Memorandum of Understanding (MOU) with MassBio to encourage and promote cooperation between members. The MOU confirmed a commitment to facilitating transatlantic investment and partnering by encouraging collaborations between each group’s member companies. The GTP and MassBio will promote each other’s investment and partnering events, offering members reduced

rates. “This is a significant partnership that brings together the trade groups for two of the world’s largest life sciences clusters”, said Robert Coughlin, President & CEO of MassBio, “The UK is a recognized leader in drug discovery and development, and we are pleased to offer our members opportunities to collaborate and partner with some of UK’s premier life sciences companies”. A second MOU was signed in December 2009 with the Massachusetts Medical Device Industry Council (MassMEDIC), to actively encourage cooperation and collaboration between UK and US companies in the medical device sector. Subsequently, Harriet signed a third MOU with Joe Panetta of BIOCOM (the cluster group in San Diego) on behalf of The GTP at BIO 2010 and a fourth MOU was signed by Harriet and Jon Rees with Gail Maderis, President of BayBIO (the cluster group in San Francisco) at Genesis 2010. As the collaboration continues to grow we look forward to offering new and exciting opportunities for our members to enable them to do business in the global marketplace. For more information please contact harriet@onenucleus.com

One Nucleus Directory 2011

www.onenucleus.com

One Nucleus Directory 2011

One Nucleus Collaborations One of the clear messages I received from members when I first joined the company, was a plea to work collaboratively with other organisations and cut down the duplication of efforts in the UK. This feedback has helped us carve out our strategy and this, combined with a request from members to create connections with international organisations who can help our members grow, is at the heart of what we stand for.

A clear recognition of the these was the formal merger of ERBI and London Biotechnology Network in May 2010. We also of course have our four Memoranda of Understanding in place as part of the Golden Triangle Partnership (see page 34) – with BayBIO, MassBIO, MassMedic and BIOCOM in the USA. The spirit of partnership is very strong in the One Nucleus team and we have enhanced our offer for members further recently, with partnerships with other organisations. These include: l An exclusive deal with Worldwide Business Research (WBR) for their events l A deal with Pharma Licensing Group (PLG) for mutual member benefit l A deal with BioPartner UK for mutual member benefit

At the end of 2010 we signed an agreement with BIONOW for their members to have access to our Group Purchasing Scheme – thus creating benefit for their members in terms of savings and importantly the critical mass of companies using the scheme – which puts us in a very strong position when re-negotiating contracts with Preferred Suppliers. We also have deals in place with other international organisations, for member benefit. These include reciprocal support from TVG Group (which runs BioPartnering Europe and other major events) and EBD Group (which run Bio Europe and BioPharm America, to name but two).

We are also working closely with other membership organisations in the UK, including the BIA (the national trade association), BIONOW (a membership organisation based in the North West) and Nexxus (Scotland).

www.onenucleus.com

Putting Safety into Practice Heptares Therapeutics is a drug discovery company focused on identifying novel drug candidates targeting high-value, validated G-protein-coupled receptors (GPCRs) in multiple disease areas. The Company’s unique StaR™ technology enables Heptares to engineer and purify stable GPCRs to which it can apply contemporary drug discovery approaches, such as crystallisation and structure-based design, biophysical analysis of ligand interactions and fragment screening. This unique approach is expected to radically improve the chances of finding novel drug candidates (small molecules and biologicals) to previously intractable targets and will enable the development of safer and more selective therapeutic agents. Based on this integrated drug discovery capability, Heptares aims to progress promising candidates internally and through strategic alliances.

HEALTH AND SAFETY WORKS LTD

can provide

Reviews, audits, risk assessments. We have knowledge of the Biotech industry, Biosafety, radioisotope use, DSEAR and REACH n Refurbishment and Construction safety, site audits, safety plans and CDM requirements. n

For more information, please contact: Dr Barry Kenny Heptares Therapeutics Ltd BioParkBroadwater Road Welwyn Garden City Hertfordshire AL7 3AX, UK Tel: 01707 358627 Email: barry.kenny@heptares.com Web: www.heptares.com

IOSH Safety Training and Bespoke Safety Courses

TEL:FAX EMAIL

01223 265622 MOBILE 07974 799808 advice@healthsafetyworks.co.uk

REDUCE BUSINESS COSTS BE LEGALLY COMPLIANT n REDUCE ABSENTEEISM n

London Associates

HSW Health & Safety Works Ltd

An independent specialist recruitment agency based in St Ives, Cambridgeshire and formed in 1988 to serve the Scientific and Medical Devices industries across the UK and into Europe.

Industrial Design Consultancy

Delta Consultants Scientific and Medical Recruitment offer staffing solutions across the scientific (including Laboratory, Analytical and Life Sciences) and Medical community. Mainly recruiting for customer facing positions in sales, marketing and field service Delta also assist our clients with other in-house or field based laboratory and scientific roles including Health and Safety, Production/R&D and Telephone Support roles.

DELTA

www.la-design.co.uk

We don’t see problems, just opportunities, and have an enviable record of success based on our knowledge of the industry, the personal service we offer, our “can do” attitude and our ethical approach.

For a discussion or full presentation on London Associates’ product development capability, telephone Les Stokes on 01442 862631 or e-mail les@la-design.co.uk

LA client: ELGA www.purelabflex.com

One Nucleus Directory 2011

Delta Consultants Scientific & Medical Recruitment The Old Courthouse, Priory Road, St Ives, Cambridgeshire, PE27 5BB Tel: 01480 495 047 Fax: 01480 493 310 Email: delta@delta-consultants.com Twitter: www.twitter.com/deltarecruiters

www.delta-consultants.com

Jenkins & Jenkins Limited Leys Barn The Leys Tostock Bury St. Edmunds Suffolk IP30 9PR Uk

Aim Jenkins and Jenkins is an independent company focusing on a wide range of facility management issues.

Company Profile Brian Jenkins is the principal consultant. Brianâ&#x20AC;&#x2122;s broad background and experience comes from over 30 years in the biopharmaceutical industry. During this time he has specialised in laboratory design and construction of a number of research and development facilities. Brian has also been involved in project managing a number of company relocation moves to their new facilities. As an independent Facilities Consultancy Jenkins & Jenkins is able to take on a variety of roles depending on the specific requirements of the client. A typical brief would be to act as client representative on a building project, either on a major refurbishment scheme or a new build project.

THE AUTHORITY IN CONFERENCE EXPERIENCES FOR PROFESSIONALS With over 25 years of experience in providing quality conferences and seminars for healthcare professionals n using high-profile speakers

We have created Kershaw Technology Services to support the development of medical devices. We have extensive experience in the following areas: l Development of carded and knitted fibrous products l Development of fibre spinning processes l Development of gel products l Application and processing of polysaccharides

n covering the latest topics and trends

l Development, analysis and modelling of chemical processes

n delivered at great venues

l Physical and chemical characterisation of raw materials and products

n at a competitive price

In-house training and online courses also available.

The Training You Deserve For more information: Tel: +44 (0)1483 730071 Email: info@management-forum.co.uk

www.management-forum.co.uk

l Project management of product development and launch processes l Development of experimental laboratory scale processes and facilities l Development of pilot scale facilities for clinical trial manufacture l Development of manufacturing facilities l Manufacture of clinical materials l Product stability and shelf life evaluation of products l European medical device regulation

Contact Details Mob: 0776 3256 112 Email: enquiries@kershawtechnologyservices.co.uk web: www.kershawtechnologyservices.co.uk

www.onenucleus.com

Safety Information Services Limited- SIS Share the load safely with SIS. SIS is a professional Independent Consultancy providing pre-clinical services to pharmaceutical, clinical, veterinary, biotechnology and medical device companies.

Checklist assified Material Cl

ents re requirem 3 Temperatu tood rs de un d designed an d provided an Packaging sit 3 an tr r fo prepared ry d regulato d Customs an epared an pr on ti ta documen 3 completed checked 3 quirement Licence re ansit 3 ady for tr Material re

We have broad experience in the design and interpretation of preclinical studies, including pharmacology, safety, pharmacokinetics and metabolism. We have contributed to the successful development of a number of new products emanating from industry and academia. We assist at all stages of the product life cycle, advising on appropriate development strategies.

Here At SIS We: l l

l l

We’re more than a courier… UK Cambridge: (01223) 245223 Japan Osaka: (+81) (0) 6-664-6664

USA Boston: (+1) 617 623 0544 San Francisco: (+1) 650 685 5511 China Shanghai: (+86) 21 6160 1550

design, monitor and interpret studies contracted to CROs create the appropriate section of an IMPD for a (Clinical Trial Application) or a CTD (for Marketing Approval) prepare expert reports, such as NCOs (for registering generic products) undertake due diligence, literature reviews and prepare papers for publication.

We also have an extensive network in the biotechnology and pharmaceutical industry and academia.

Ian Smith, BSc, PhD, DipRCPath. Principal Safety Information Services Limited.

We are happy to discuss any project developing new therapies.

E: Ismith1945@aol.com T: +44 (0) 1606-301767 M: +44 (0) 7985-074060

Would you like to promote your business? NeuroSolutions was established to provide high quality translational neuroscience contract research services. We specialise in the design and delivery of efficient, focussed preclinical research packages, using electrophysiological recording techniques for nervous system indications such as pain, neurodegeneration (Alzheimer’s and Parkinson’s disease), psychiatric disorders, movement disorders and obesity. We prepare your compounds for clinical development by providing a flexible, highly skilled service with fast turnaround tailored to the clients needs, delivering key proof-of-concept, drug efficacy, mechanism of action data and more. Our global clientele ranges from small, “startup” biotechnology companies to major, multinational pharmaceutical establishments.

NeuroSolutions Limited info@neurosolutionsltd.com www.nsolns.com

One Nucleus Directory 2011

We have a mag for that... If you would like to promote your business in any of our publications please contact Distinctive Publishing on 0191 4788300 or email production@distinctivepublishing.co.uk Please visit www.distinctivepublishing.co.uk to view examples of our publications and a complete list of all the titles we produce.

Know Your Business PharmaMatrix UK has been in operation for over ten years, offering bespoke marketing and communication strategies to a range of industrial / commercial / academic clients.

Operating within a dynamic environment means we require up to date and relevant market information. Whether your company is taking a block buster drug, a medical device or new technology to market, the same principles apply. Success can only be assured by knowing your customer requirements, understanding the market, and targeting a supportive communication strategy. Getting to know your business and your market aspirations is important to us. Adding value to your existing team is my personal mission. The scope of any project can range from a few hours support to a long-term strategic business and communications plan. We also offer a dedicated mentoring/training service for your employees to develop these skills in house. PharmaMatrix UK can assist in defining creative workable solutions for a wide variety of business needs.

Tel: 07855 311393 helensmith@pharmamatrixuk.com

www.onenucleus.com

Babraham Boosts Bioincubator Facilities Acknowledged as one of the UK’s leading enterprise hubs, home to both world-class academic research and commercial biomedical companies, the Babraham Research Campus has established itself as a hub of bioscience innovation in the heart of the Cambridge cluster. With world-class facilities and a vibrant research community, the Babraham Research Campus continues to expand and has recently attracted some of the most exciting biologics and antibody companies in Europe. The opening of a fourth Bioincubator Building in November 2010 underscores Babraham’s continuing commitment to nurturing early-stage enterprises and supporting biomedical innovation in the region. Even in the current economic climate, the campus is expanding; November 2010 saw the opening of the fourth Bioincubator building, Maia, named after the Roman goddess of growth. Constructed with financial support from BBSRC, Maia provides seven early-stage biomedical companies with flexible lab and office space, cell culture and high-class level 2 containment facilities. The campus currently provides around 64,000 sq ft of lettable lab and office space. Four biologics spin-out companies joined the campus during 2010: Kymab, a spin-out from the Wellcome Trust Sanger Institute, Bicycle Therapeutics from the MRCLMB, Recombinant Antibody Technologies and Crescendo Biologics, whose technology is derived from BBSRC-funded research. “Much of the pioneering work on monoclonal antibodies was carried out at the Institute and in the Cambridge area, so it is particularly thrilling to see so much commercial expertise gravitating to Babraham,” explained Babraham Institute Director Professor Michael Wakelam.

At the cornerstone of the campus is the internationally regarded Babraham Institute, an institute of the Biotechnology and Biological Sciences Research Council (BBSRC), underpinning government’s national responsibilities for bioscience research and training, specifically health and pharmaceuticals.The Institute commercialises its discoveries through its commercial arm, Babraham Bioscience Technologies (BBT) Ltd, an example being the creation of Crescendo Biologics Ltd, and aims to initiate and facilitate partnerships to promote knowledge exchange and translate innovative science into viable ventures. Investing in Infrastructure for Bio-innovation BBT has successfully developed the campus infrastructure over the last twelve years; central to this are Babraham’s Bioincubator buildings, which offer serviced facilities, on attractive, flexible terms, to support new bioventures and catalyse the commercial exploitation of biomedical research. Around 30 early-stage biomedical companies are today based at Babraham, delivering new products and innovative solutions for the healthcare challenges of the 21st century. However, 69 companies have passed through the Bioincubator and these companies have raised in total over £366M in equity finance. 42

One Nucleus Directory 2011

Mark Doran, Director of process development and manufacturing at Alpha Biologics, which has just moved into Maia, said, “There’s a real hub of monoclonal antibody expertise that’s coming together here. More and more companies have come on site over the past few years because Babraham is getting recognised as the place to be. There’s a real sense of community here – and the practical and technical support is exceptional.”

BABRAHAM BIOSCIENCE TECHNOLOGIES LTD (BBT) n

“The access to short term rented lab space within the TDL at Babraham has been of real benefit to Cellexus Ltd. The speed with which the contract was set up, the flexible approach and the competitive pricing all made for a smooth process. Additionally the TDL staff was readily available for advice and access to the on-site stores facility was another key benefit. The flexible provision of such short-term space is not, to my knowledge, available elsewhere in the Cambridge area.” Access to Babraham’s World-Class Scientific Facilities Companies located in Babraham’s Bioincubator also have access to the Institute’s world-class science facilities. Recent BBSRC investments include a £1.6M Next Generation Sequencing facility, a £1.5M Mass Spectrometry suite with special application for lipidomics’ analysis, £23M world-class rodent animal facilities, in addition to bioinformatics, FACS analysis, imaging, gene targeting, monoclonal antibody production and proteomics. Catalysing Academic-Commercial Collaboration Another clear draw of the campus is the opportunity for companies to interact and collaborate with Institute research groups, where BBSRC-funded research is directed towards understanding the basic bioscience underpinning lifelong health and wellbeing. Babraham research has given insight into conditions like hypertension, heart failure, autoimmunity, infertility, cancer and neurodegenerative diseases such as Alzheimer’s Disease and today has a strategic focus on ‘healthy ageing’, to understand the biological mechanisms underpinning the determinants and the maintenance of lifelong health. The Institute is committed to knowledge exchange and facilitating academic-commercial links to drive innovation and wealth creation. The translation of the Institute’s pioneering epigenetics research has resulted in several patent applications; commercialisation has been achieved through licensing to companies, including an ongoing relationship with CellCentric Ltd. Several events are organised throughout the year to bring together institute scientists with companies on site, for example CEOs’ Breakfasts and Knowledge Exchange Open Days. A significant number of the companies on site are closely integrated with the Institute, working with scientists or using Institute services and facilities, such as the Technology Development Lab (TDL).

Andrew Sandham, Chairman and CEO of Kymab said, “We evaluated many locations in the Cambridge area to found our business. We chose the Babraham Research Campus because of the high quality of research laboratories, its proximity to academic centres of excellence and its flexibility in providing the capacity and services we will need as we expand our R&D operations.” Derek Jones, Chief Executive of BBT said, “The creation of a supportive, entrepreneurial environment promoting bioscience innovation is one of our key objectives as we continue to develop the Babraham Research Campus. I am delighted at the progress we have made and the opportunity that the new building presents to support bioscience innovation and wealth creation for the UK.”

“Babraham was chosen as the site for our laboratory because of the impressive facilities available there, the great location and the track record of support for small companies shown by BBT.” - Dr John Tite, CEO of Bicycle Therapeutics

Accelerating Innovation in the TDL Another unique offering at the Babraham campus is the Technology Development Laboratory (TDL), established to provide access to resource, equipment and space so that early-stage concepts can be developed to commercial opportunities. This provides the benefit of offering bespoke, state-of-the-art R&D services and scientific assistance across many fields including molecular biology, protein biochemistry, cell biology, immunology, medicinal and synthetic chemistry. A suite of equipment for biopharmaceutical development, supported by funding from the East of England Development Agency (EEDA), includes a medium-scale cell culture and fluorescence-based assay platform, together with state-of-the-art protein purification and analysis systems. EEDA funding also supported the purchase of a Biacore T100, which is available at a reduced day-rate to One Nucleus members. All the campus companies, Institute scientists and external biomedical companies can use the TDL. It’s not just Babraham-based companies that are taking advantage of the TDL. Cellexus Ltd, based at the Hinchingbrooke Business Park developing bioreactor systems, used the facility to run evaluation experiments for three weeks. Clive Mason, Technical Manager explained, www.onenucleus.com

RSA is a global leader in Executive Search, Interim Management and Talent Management to the Life Sciences industry. Our consultants talk to hundreds of industry leaders daily, our network reaches every corner of the global life sciences industries. Our unique blend of knowledge, teamwork and integrity has made us a world leading executive recruiter but we’ve never lost sight of the values we started with: respect, integrity, quality and professionalism. EXECUTIVE SEARCH Top people are sought-after people. We use our experience to create the right approach for each key appointment, deploying our network and industry knowledge to achieve exceptional success rates.

It can help individuals clarify their priorities, achieve targets and develop long term strategies for success. Through greater awareness and assurance they can become more confident in their decision making and leadership style.

In the executive search industry, around 65% of assignments are successful. With RSA, it’s more than 90%. Why? Firstly, we have inside knowledge. Many of our consultants and researchers have worked in life sciences, all of them are highly qualified and experienced. Secondly, everyone at RSA shares information and contacts across the globe and we reward them as a team not just as individuals.

Development

RSA helps you engage the most talented people exactly when you need them for as long as you need them. As the leading provider of interim managers to the life sciences industry, we have dedicated interims teams worldwide.

We provide people with relevant and inspirational learning experiences to focus their development in line with their aspirations and potential. Physiological principles, models and tools are fundamental to developing learning and identifying the correct development opportunities. We use experienced psychologists in a business and educational context to facilitate this process.

TALENT LIFECYCLE SERVICES

NON EXECUTIVE DIRECTORS

INTERIM MANAGEMENT

RSA’s Talent Lifecycle Services deliver a proven link between the Board and its HR partners. We work with clients to maximise the value and contribution of their employees in the mid-to-long term. We achieve this through a comprehensive set of services that are clearly linked to and driven by their organisation’s strategy, goals and values. Engagement We help companies understand what great leadership looks like in their organisation and guide them in defining organisational strategies that will create competitive advantage. Great leaders develop a clear strategic perspective for their business, defining what the vision should be and inspiring their people to action. The capability and quality of leadership talent is a vital ingredient of success. RSA has the expertise, tools and experience to partner with clients to work with the present leaders as well as identifying and developing future ones. Assessment The assessment of individuals within a work environment should be robust, fair and relevant to their business. We work closely with our clients to understand the specific behaviours and skills required to make their businesses successful. We design and deliver one-to-one assessment programmes and assessment centres to suit a wide range of needs and budgets. Whilst our first choice is to recommend bespoke exercises tailored specifically to the organisation, industry, role and/or future need, we also have a range of “off the shelf” exercises which can be adapted if required. Coaching Coaching develops leaders, improves performance and builds independence. 44

Successful organisations are made up of people who drive the business forward and optimal drive requires individuals to have the passion, motivation and belief in what they are doing.

One Nucleus Directory 2011

Working at the top levels of our clients businesses and dealing with senior leaders in the industry takes RSA beyond the placement of executive positions and we regularly consult with our clients about their needs for Non-Executive Directors. Identifying independent, experienced and authoritative NonExecutive Directors can be a major challenge to even the most well-established life sciences companies. RSA maintains a Non-Executive Director register which brings together the small, but powerful, niche community of Non-Executive Directors. The register facilitates networking, produces research into the challenges and opportunities of Non-Executive Directorship, and places qualified individuals into Board vacancies with life sciences companies (within both the public and private sector). SO WHAT DO I DO NEXT? Wherever you are and whatever the time, we’re ready to get to work. Call or email us now and speak to Keith Hobson : +44 (0)1707 259333 or keith.hobson@theRSAgroup.com

www.onenucleus.com

Keeping on the Right Side of the Law

by John Dean - Distinctive Publishing

The law, it is said, is a minefield, which is why seeking expert legal advice is crucial in so many situations. Those people who have tried to save money by dispensing with the services of a solicitor have often found themselves deep in trouble because they ignored that basic mantra. The reason lawyers are so important lies in the complexity of law, a complexity that is constantly changing. Take business law: everything from health and safety rules to production legislation can present challenges and a single mistake can lead to a potentially costly breach. The result could be a fine, a court appearance or a large compensation pay-out.

There is also a myriad of law surrounding competition: when is a claim unfair, is a product over-hyped, are the statements made about it correct, is an unfair advantage being taken over a competitor? Or by a competitor?

Patent law is important as well because, once an idea is recognised as unique and owned by one particular individual or company, then it is protected. By registering a product or idea, there is a paper trail which can be used should it turn up elsewhere.

But within the medical sciences field, there is another reason why the law is so important. In a sector where innovation is constantly bringing forward new ideas, companies need to be aware of the legislation governing Intellectual Property (IP) and Patents.

Each and every one of these areas presents great challenges for companies and may require expert legal guidance and so it is always worth seeking out those companies that specialise in the field in question.

IP is crucial because many companies within the industry come up with ideas which are developments of existing science and technology and defining how to protect them is crucial. That is why understanding IP and knowing how best to register new ideas is important for companies. More than one company has lost out on millions in profits because they were too slow to register their idea as unique.

Some lawyers specialise in workplace legislation, for instance, others are experts in IP and Patents, others can advise on health and safety and the law relating to contractors. Each area holds within it the potential to cause a business major problems but by hiring in experts the chances of anything going amiss is greatly reduced. The basic, overriding message is never mess with the law. Never assume that you know better than the experts, never gamble on the â&#x20AC;&#x2DC;barrack room lawyerâ&#x20AC;&#x2122; who reckons they are right and never leave something till tomorrow that you need to know today. Ignoring the advice can be as costly as it comes, seeking and taking advantage of it leads to peace of mind and a company that is much more secure.

One Nucleus Directory 2011

www.onenucleus.com

Experts in Genome Content Management! Eagle Genomics are experts in genome content management. The company’s flagship Elastic Eagle™ provides a timely, cost-effective and appropriate bioinformatics outsourcing solution that suits all organisations using genomic data from big pharma to the smallest startup biotech companies, and across all sectors from drug discovery and crop improvement through to animal health and food safety.

Elastic Eagle™ l l l l

Visualization/integration - public and private data side by side Analysis - processing and mining of large datasets Management - genomic data storage query and retrieval Security - secured mirrors of public resources

Track Record

l Delivering outsourced projects of all sizes on time and on budget to a number of the world’s largest

pharmaceutical and agribiotech organizations

l Close collaboration with key open-source academic projects l Elastic Eagle™ is everything organizations need to outsource bioinformatics projects

Babraham Research Campus, Babraham, Cambridge, CB22 3AT Email: info@eaglegenomics.com Tel: 01223 654481

www.eaglegenomics.com

One Nucleus Directory 2011

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Pharma & Medical Solutions RAUMEDIC AG,is a flexible company full of bright people and new ideas, operating from state of the art Class 7 clean room facilities near Nuremburg. Current research and development includes novel medical grade material alternatives, micro extrusion, devices with electronics, as well as a number of exciting custom developments for the medical device and pharma industry.

RAUMEDIC have significant experience in delivering design, development and full contract manufacturing services including full high volume automation with robotic handling, for your medical or pharma device requirements. Our engineers will work with you to advise on materials, design and construction, automated manufacturing, packaging, sterilisation and validation protocols, as well as quality and regulatory support to enable you to CE mark your product. Contact our UK team Paul Flavell (07785 714815) or Mark Laycock (07802 333916) for further information. info@raumedic.com www.raumedic.com Raumedic UK Hill Court Ross on Wye, UK HR9 5QN

www.onenucleus.com

Statistical consulting and clinical trial reporting Email: info@phastar.co.ukÂ Telephone: 0207 183 7062

ProPharma Partners Limited Company resource constraints can limit successful business and product development. Our partners all have extensive experience across large pharmaceutical and entrepreneurial biotechnology companies. We have offices in London, San Francisco and Tokyo and we assist clients as diverse as BioVex, Acambis, Abbott and Daiichi in successfully achieving their business goals.

Call and see how we can help: Peter Cozens or Donna Hackett on + 44 (0)1293 425 300 E mail@propharmapartners.uk.com www.propharmapartners.biz

One Nucleus Directory 2011

Key areas we consult in include: l global product and patent licensing l corporate partnering l merger and acquisition advice and due diligence l intellectual property strategy and management l business development strategy l pre, clinical and regulatory strategy development and implementation.

Verius Limited Clinical Safety and Pharmacovigilance Services

Verius Limited offers a complete range of clinical safety and pharmacovigilance services, with a unique ability to tailor a bespoke package directly to your needs. We have global capabilities and work within all applicable regulatory requirements. In todayâ&#x20AC;&#x2122;s environment there is an ever increasing focus on safety of new products. Verius can provide support ranging from a basic clinical safety service for a new drug or device candidate, through to a sophisticated system encompassing data capture, narrative writing and electronic adverse reaction reporting to regulatory authorities and the EMA that will support an entire development programme. We can provide full medical monitoring for clinical studies through our in-house physicians, all of whom have extensive experience in the medical management of global clinical development programmes. With our E2B and 21 CFR part 11 compliant industry standard fully validated safety database systems (ArisG and TARA) we can produce Individual Case Safety Reports, monthly line listings, annual safety reports and periodic safety update reports. Starting with protocol and case report form review and investigator training through to the end of study reports and case narratives, we are able to provide the clinical safety expertise needed for clinical trials at every stage. Verius also offers a full pharmacovigilance service for marketed products, including the provision of EU qualified persons for pharmacovigilance, capture of spontaneous reports, literature searches, signal detection and establishment and maintenance of a complete global safety database.

(ICH) and all major regional and national regulatory agencies in Europe, North America, Japan and elsewhere. We have a successful track record in Orphan Drug applications in the EU and elsewhere, and have guided clients through Scientific Advisory procedures at national and European level. Our associate company, IDEA (Innovative Drugs European Associates Limited) offers legal representation services for those companies without an EU presence, ensuring full compliance with the requirements of the Clinical Trials Directive. General consulting services These cover all aspects of drug development. We have specific in house experience in molecular biology and genetics, cell culture, microbiology and immunology. We are currently helping clients with their development plans in a wide range of therapeutic areas, creating focussed project teams working in tandem with your in house development staff. Through our associate FSA registered company, we are able to help with fund raising and other aspects of venture management, legal services and corporate finance. Verius Limited would be pleased to provide further information on these and other services we can offer. For further information please contact Dr Stephen Bentley on +44 (0)1223 402660 or by e mail at enquiries@verius.co.uk

Risk/benefit analysis and risk management plan reviews can be provided by Verius at any stage of the product life cycle. We have the required skills to monitor the safety of your product from the clinical stages through post marketing. With our wide experience and knowledge we offer the complete solution. Regulatory Services Our full range of regulatory services covers all stages of drug and medical device development, and encompasses manufacturing and quality, non-clinical and clinical aspects. We have experience with new and existing synthetic molecules, biologicals, as well as other novel technologies and devices. We are compliant with the requirements and guidance of the International Conference on Harmonisation

www.onenucleus.com

Synapse Clinical Research Services was founded by Dympna Starling in 2007, offering flexible and independent GCP and GMP QA consultancy. Services offered are tailored to meet clientâ&#x20AC;&#x2122;s needs, and include MHRA inspection preparation, internal system and facility audits, process improvement, GCP and GMP training, SOP writing and review. Most organisations have times when the workload is too much: a project is starting up, an MHRA inspection is due, internal audits or vendor audits are overdue or a member of staff is unexpectedly away. A flexible and independent QA consultant is just what you need at times like this, so pick up the phone, or e-mail me!

6 Harding Way, St. Ives, Cambridgeshire PE27 3WR M: 07775 923997 | E: dympnastarling@synapsecrs.co.uk

One Nucleus Directory 2011

www.synapsecrs.co.uk

www.onenucleus.com

One Nucleus Directory 2011

Fast Forwarding Drug Discovery Pharmidex provides high quality, specialist CNS, ADME/PK, drug safety & bioanalytical services for lead optimisation through to drug development allowing our clients to quickly and cost-effectively identify and progress their new medicines. We have years of drug discovery expertise to help you fast forward your drug discovery programmes Since 2002, Pharmidex has established itself as the world leading centre for studying CNS drug distribution and biochemical responses to new drugs using its proprietary NeuroPK® and NeuroPD® technologies. Using these technologies drug action can be associated with free drug levels at the target site and systemic pharmacokinetic data. Clients can therefore progress their compounds based-on high quality, translational scientific data which can be much more closely linked to clinical outcomes and likely clinical success. We focus on the key data, decision-points and milestones that allow our clients to make the best decisions possible for their programmes and portfolio. Pharmidex Prides Itself On: n n n n n

Clients can select from the extensive platform technologies or request bespoke studies to address specific needs, all of which are rapidly undertaken by highly qualified scientists from academic and industry backgrounds. The Scientists and Management Team at Pharmidex have extensive knowledge of discovery and development of new drugs, covering a broad range of drug targets. Pharmidex has its own research activities which include providing clients with a drug delivery technology to the brain called Cerense; this technology can improve the brain uptake of both large (macromolecules) and small, new or existing drugs offering better efficacy, less side-effects or just delivering therapies that could never access the brain. Pharmidex has a very successful track record in obtaining financial support for our scientific development via grant applications in the US, UK and EU and by partnering on a ‘shared risk-shared reward’ basis with other companies. This proven approach has led to the co-development of the CNS delivery system, Cerense with Genzyme Pharmaceuticals. Tel: +44(0)870 240 5978 Email: business@pharmidex.com www.pharmidex.com

Customer care and satisfaction Flexible and broad range of study options High quality data Fast turnaround times Value for money

Today Pharmidex provides an extensive range of in vitro, in situ and in vivo ADMET/PK technologies covering a wide range of species, to underpin its world leading CNS expertise.

Pharmidex service offerings are not limited to the below:

IN VITRO SCREENS

IN VIVO ADME / PK

CNS

SAFETY

BIOANALYSIS

CYP450 inhibition, induction, TDI, phenotyping

Freely moving cannulated or terminal PK in range of species

Microdialysis - free drug & neurochemicals in various brain regions) in freely-moving species

Acute or chronic dose ranging / escalation studies

LCMSMS Platform for drug discovery support

Permeability/ Pgp interactions (MDCK/ CaCo2)

Cannulated (combined) portal, biliary vascular studies

Brain uptake index and In situ brain perfusion

Pathology / toxicology studies

Small and large molecule quantitation

Metabolic clearance (microsomes /heps / S9)

In-situ organ perfusion studies

Serial CSF and plasma sampling and “Brain free fraction” assay

Clinical biochemistry, histology and IHC

Radiolabelled studies

Protein & tissue binding (free and bound)

Pulmonary absorption studies

CNS safety / efficacy studies In conscious rodents

Toxicokinetics and PKPD

Bioassay method dev. and validation

Biofluid stability / blood distribution

Tissue distribution / uptake studies

CerenseSM - Improved delivery of small and macro molecules to the brain

CV safety in rodent species

Neurochemicals by EC

www.onenucleus.com

One Nucleus Directory 2011

Ascot International Personal Care Chemical Distributors • Anti ageing/wrinkle • Aromatherapy and Massage Oils • Hair Care • Insect repellent • Natural and Organic Oils • Skin Lightening and Tanning • Sun & UV-Care

Ascot International (1996) Ltd Welcroft Street, Stockport, Cheshire SK1 3DF (UK) Email: ns@ascot1.com Web: www.ascot1.com

Service Support Supply

(+44)

161 476 6161 www.onenucleus.com

Innovative Medicines Dr Reddy’s is a relatively young company, started just 25 years ago in India by Dr Anji Reddy with the purpose of “Providing affordable and innovative medicines for healthier lives”. In its short history the company has achieved many significant milestones. In 2001 it was the first Asia Pacific pharmaceutical company outside Japan to be listed on the New York Stock Exchange. The company has grown quickly to exceed $1. 5 Billion sales.

The company now comprises of 3 main business units: The Proprietary Business comprises of New Chemical Entities (NCEs), biosimilars, and differentiated formulations. The Global Generics Business markets over 200 branded formulations across the world, with over 50 products marketed in the US. The third business unit is Pharmaceutical Services and Active Ingredients which comprises of the Active Pharmaceutical Ingredient (API) and Custom Pharmaceutical Services (CPS) businesses. The API business offers over 150 APIs and has a further 20 in development. CPS aim to offer a full range of development and manufacturing services supporting all stages of the pharmaceutical product lifecycle. This includes initial product development, support to clinical trials, full scale commercial manufacture of both API and dose form, with the option of supply from a range of worldwide FDA approved locations. Dr Reddy’s has a strong technical capability and focuses on enabling value through technology. It has particular strengths in chiral chemistry, marketed under the Chiirotec brand. This is based on world leading experience of asymmetric hydrogenation and hydroformylation and an extensive collection (over 2000 microorganisms) of industrial biocatalysts many of which have been successfully operated at scale.

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The company also has extensive general chemistry experience gained from manufacturing over 150 APIs at manufacturing scale and constantly searching for more efficient processes to support the company ambition to provide “affordable and innovative medicines.” CPS has access to this expertise but also takes care to provide information firewalls between customer projects to protect proprietary information and preserve confidentiality. CPS have specialist expertise in the manufacture of prostaglandins, steroids and Activated mPEGS. The activated mPEG offering is supported by in house manufacture of mPEG alcohol. CPS activity is supported with over 300 scientists based in 3 centres (two in Hyderabad, India, one in Cambridge UK). Research laboratories are equipped with the latest state of the art equipment including DSC/TG, GC/ LC-MS, LC-MS-MS, powder XRD, single crystal XRD, NMR (up to 500mhz), LCNMR, FT-IR, CHN analyzer, ICP-MS A single Project Management framework is used across the company based on modern critical chain principles. Work is executed through multifunctional Project Execution Teams which include experts in R&D, analytical R&D, QA, regulatory affairs, EHS, Engineering & supply Chain as required by the project. Manufacturing scale ranges from laboratory through Kilo lab to multi tonne capability with FDA & MHRA approved locations in Hyderabad, India, Cuernavaca, Mexico & Mirfield, UK. Each site has it’s own local multifunctional resource (QA, QC, Supply Chain, Engineering) but also has access to the company’s significant resource if required.

Design and Manufacture from a local UK source. Briton EMS has been delivering a complete electronic manufacturing service from Bedford since 1979. We are proud to announce a new partnership with leading Cambridgeshire based Product Design Company “42 Technology”, through which we are now able to offer a full product design and manufacturing service including Mechanics, Plastics, Electronics design, Firmware and Software. In partnership with 42 Technology we are a true “one stop shop” for full product design and manufacture.

Briton EMS has key skills and processes which are specifically aligned to building complete finished and fully tested products. We offer a rapid prototype service, and UK production in medium volumes for industry sectors such as instrumentation, medical, broadcast, wireless, RF, gas detection and control systems.

www.onenucleus.com

S-Tech Insurance Services Ltd 154-156 Victoria Road Cambridge CB4 3DZ One Nucleus free-phone enquiry number 0800 8406540 Tel: 01223 324233 Fax: 01223 464150 Web: www.s-tech.co.uk Email: info@s-tech.co.uk

Independent insurance, financial services & risk management group

S-Tech recommends and provides solutions:

At S-Tech, we have available a complete Insurance service to manage your business and personal insurance requirements. All One Nucleus member companies and their staff can benefit from the services we offer:

Commercial Insurance:

Specialist policy wordings with cover enhancements are available to the membership Discounted premium rates. We have a number of insurance facilities available that are specifically designed to accommodate the requirements of the Biotech, Medtech, Life Science Industries and Start Up Companies.

Credit Insurance:

Our Credit insurance team have access to a number of Underwriters who will consider enquires including: n Whole Turnover n Key Accounts

Personal Insurance:

Our Personal Lines department provides: n Bespoke Home and Contents insurance n Motor Insurance

Financial Services:

Our Independent Financial Advisors can provide Companies and Individuals with solutions to match their requirements in areas such as: n Employee Benefits n Pensions n Shareholder Protection n Investment Advice

Would you like to promote your business? If you would like to promote your business in any of our publications please contact Distinctive Publishing on 0191 4788300 or email production@distinctivepublishing.co.uk Please visit www.distinctivepublishing.co.uk to view examples of our publications and a complete list of all the titles we produce.

We have a mag for that...

One Nucleus Directory 2011

One Nucleus Corporate Sponsors

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Barclays Corporate Nick Baker Nick.W.Baker@ barclayscorporate.com www.barclayscorporate.com Barclays Bank Plc, Mortlock House, Vision Park, Histon, Cambridgeshire CB24 9DE

With a clear focus on client relationships, Barclays Corporate provides integrated banking solutions to businesses with an annual turnover of more than £5 million or its currency equivalent. We serve our clients via a global network of relationship, industry sector and product specialist managers, who provide tailored solutions to meet their needs. These include lending, risk management, trade, cash and liquidity management, and specialist asset and sales financing. Additionally, clients are offered access to the products and expertise of other businesses in the Group, particularly the investment banking solutions of Barclays Capital and the private wealth management expertise of Barclays Wealth. Barclays Corporate employs over 12,000 people globally. For more information please see www.barclayscorporate.com. About Barclays Barclays is a major global financial services provider engaged in retail banking, credit cards, corporate and investment banking and wealth management with an extensive international presence in Europe, the Americas, Africa and Asia. With over 300 years of history and expertise in banking, Barclays operates in over 50 countries and employs nearly 147,000 people. Barclays moves, lends, invests and protects money for 48 million customers and clients worldwide.

G H

For further information about Barclays, please visit our website www.barclays.com.

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Deloitte Mr Stuart Henderson

www.deloitte.co.uk

City House, 126-130 Hills Road, Cambridge CB2 1RY

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Deloitte is the UK’s fastest growing major professional services firm in 21 locations, with over 10,000 staff nationwide. The Cambridge office of Deloitte boasts an all-encompassing client base with a highly diverse spectrum in terms of industry sector and size of clients, from small start-ups to multinational corporations. 10 Partners and over 200 staff deliver a full range of professional services to the East Anglian region. The Cambridge office has focussed on the opportunities in the technology sector; which the region has been renowned for, and the life and health sciences sector includes a diverse range of businesses. Our Life and Health Sciences practice words with a wide number of clients ranging from some of the most influential multinationals to dynamic new start-ups. To address challenges faced by these organisations we provide a broad spectrum of services spanning audit, tax, corporate finance, strategy, risk assessment and technology advice.

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Granta Park Roz Bird www.grantapark.co.uk Estate Office, McClintock Building, Granta Park, Great Abington, Cambridge CB21 6GP

The Granta Park Estate is located in the heart of the Cambridge Science Cluster. World leading companies such as Lonza, MedImmune, Pfizer, PPD and TWI have made Granta Park their home and the Riverside development and the McClintock building with accommodation to let are attracting the leading companies of the future. At Granta Park we offer: • A secure, high quality science park environment. • A specialist on site team to work with in order to manage your company’s property requirements now and in the future.

• A highly accessible Estate with a green travel plan including a commuter bus service and a location in close proximity to the main transport nodes and trunk roads.

• Demonstrable commitment to the sustainability agenda with real practical support for companies looking to achieve and maintain ISO 14001.

• Opportunities to be part of a special science community with networking lunches, free meeting facilities, café, gym, nursery and a sport and social programme. It’s no surprise that in 2010 more companies chose to come to Granta Park than any other local science or business park. Find out more at: www.grantapark.co.uk

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MedImmune Mr Jon Green Tel: 01223 471472 info@medimmune.com www.medimmune.com Milstein Building, Granta Park, Cambridge CB21 6GH

A Renowned for our originality and creativity and backed by a 20-year heritage, MedImmune is synonymous with intelligent risk-taking, innovation and entrepreneurial spirit. As AstraZeneca’s worldwide biologics unit, we strive to address unmet medical needs by developing novel proprietary products and cutting-edge technologies. As a result of incorporating translational sciences - otherwise known as “customized medicine” - into some of our programs, MedImmune is continually working towards the future. With two actively marketed infectious disease products and an advancing pipeline of promising candidates in the areas of infection, oncology, respiratory disease and inflammation, cardiovascular/gastrointestinal disease and neuroscience, MedImmune strives to provide better medicines to patients, new medical options for physicians and rewarding careers to employees. We have approximately 3,000 employees worldwide and are headquartered in Gaithersburg, Maryland with facilities in Pennsylvania, California, Kentucky, the United Kingdom, and the Netherlands. UK facilities include vaccine manufacturing operations in Speke and antibody discovery and research laboratories in Cambridge.

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Taylor Wessing Simon Walker Tel: 01223 446400 cambridge@taylorwessing.com www.taylorwessing.com

J Taylor Wessing is a major European law firm with offices in Cambridge, London, Berlin, Brussels, Düsseldorf, Frankfurt, Hamburg, Munich, Paris and Shanghai. It is recognised as a market leader in intellectual property and corporate finance and has considerable expertise in pharmaceuticals and biotechnology having acted for start ups, growing companies, big pharma and big biotech. Solicitors with leading corporate and intellectual property lawyers specialising in advising pharmaceutical and biotechnology companies and venture capital funds.

24 Hills Road, Cambridge CB2 1JW

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UCB info-uk@ucb.com www.ucb.com Tel: 01753 534655 Fax: 01753 536632

UCB (www.ucb.com) is a biopharmaceutical company dedicated to the research, development and commercialization of innovative medicines with a focus on the fields of central nervous system and immunology disorders. Employing approximately 9 000 people in over 40 countries, UCB generated revenue of EUR 3.1 billion in 2009. UCB is listed on Euronext Brussels. In the UK, UCB is located in Slough, Berkshire, and has approximately 600 employees, the majority working in research & development activities. UCB is a Top 5 investor in UK biopharmaceutical R&D.

S T U V

Slough, Berkshire United Kingdom

W X Y Z www.onenucleus.com

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World Courier Claire Brown cbrown@worldcourier.co.uk www.worldcourier.com Tel: 0207 717 1400 Fax: 0207 928 7105 World Courier (UK) Ltd, Sea Containers House, 20 Upper Ground, London SE1 9PD

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For 40 years World Courier has set the benchmark for worldwide time & temperature sensitive transportation. We remain the only specialist courier company with its own global company network with over 146 owned offices in 51 countries, operating 24 hours a day, 365 days a year. Each office is ISO 9001 certified with the same operating standards dedicated to treating every shipment on an individual, priority basis. We are able to anticipate problems and implement solutions, deal efficiently with all documentation, customs clearance, international regulations and security matters. With experience in managing the logistics of over 7,500 clinical trials worldwide, we are the acknowledged experts in handling temperature-sensitive specimen and drug shipments.

One Nucleus Gold Members

Abcam Ltd info@abcam.com

B C D E

www.abcam.com Tel: 01223 696000 Fax: 01223 696001 330 Cambridge Science Park, Milton Road, Cambridge, Cmabridgeshire CB4 0FW

F G H I J K

Abcam is a producer and distributor of high quality research-grade antibodies and associated proteomics research products; antibodies are essential tools for life scientists that enable them to analyse components of living cells at the molecular level. Since it was founded in 1998 by Dr. Jonathan Milner, Abcam has enjoyed rapid growth and is widely accredited as a leading company in its industry, with annualized turnover in excess of £60 million and growing. Headquartered in Cambridge (UK), Abcam has subsidiaries in Cambridge (US), Tokyo (Japan) and Hong Kong (China), allowing them to serve a global customer base of over 75 countries. Abcam revolutionized the buying of antibodies via its website and their online catalogue consists of tens of thousands of products, supported by hundreds of thousands of pages of accompanying data. This includes a growing range of non-antibody products such as proteins, peptides, lysates, immunoassays and other kits, which will continue as the business expands in the broader protein detection and regulation market. A key component in the success of Abcam comes from the speed with which it can bring products to market and it’s customer support efficiency. This enables scientists to find products with specific characteristics quickly, thus speeding up the pace of research into important diseases such as cancer and coronary heart disease. Abcam’s in-house expertise means they are able to source products and supplementary resources for the newest and fastest growing research areas like Cancer, Cardiovascular, Chromatin, Immunology, Neuroscience and Stem Cells. For further information, visit www.abcam.com

Amgen Limited www.amgen.co.uk Tel: 01223 420305 Fax: 01223 426314 240 Cambridge Science Park, Milton Road, Cambridge, Cambridgeshire CB4 0WD

Amgen discovers, develops and delivers innovative human therapeutics. A biotechnology pioneer since 1980, Amgen was one of the first companies to realize the new science’s promise by bringing safe, effective medicines from lab, to manufacturing plant, to patient. Amgen therapeutics have changed the practice of medicine, helping millions of people around the world in the fight against cancer, kidney disease, rheumatoid arthritis, and other serious illnesses. With a deep and broad pipeline of potential new medicines, Amgen remains committed to advancing science to dramatically improve people’s lives. To learn more about our pioneering science and our vital medicines, visit www.amgen.co.uk

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Asterand Zuleika Roberts zuleika.roberts@asterand.com

www.asterand.com

2 Orchard Road, Royston, Hertfordshire SG8 5HD

Tel: 01763 211600

Asterand is the leading global supplier of high quality, well characterized human tissue and human tissue-based research services to support drug discovery & development. We provide human based solutions to pharmaceutical and biotechnology companies to accelerate the identification and validation of drug targets and enhance the selection of drug candidates with an increased likelihood of clinical success. Asterand has a significant and well established human tissue heritage, having been formed through the combination of three leading human tissue focussed organisations. Asterand offers unparalleled access to human tissues for research through its worldwide network of collaborative donor institutions. Asterand’s Services division offers exemplary scientific expertise in collaborative human tissue research. Our PhaseZERO® platform delivers human tissue-based data supporting target & biomarker validation and compound function & safety. Our BioMAP® platform, comprising a comprehensive panel of automated, human primary cell based disease systems, enables rapid input on mechanism of action, efficacy and side effect profiles of drug candidates, providing actionable data to guide lead selection and optimisation.

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Astex Therapeutics Ltd Jeremy Carmichael, Director of Business Development j.carmichael @astex-therapeutics.com www.astex-therapeutics.com Tel: 01223 226200

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436 Cambridge Science Park, Milton Road, Cambridge CB4 0QA United Kingdom

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Astex is a UK-based biotechnology company that discovers and develops novel small molecule therapeutics in the areas of oncology and virology. Using its pioneering fragment-based drug discovery platform, Pyramid™, Astex has built a pipeline of molecularly-targeted oncology drugs, of which three are currently being tested in Phase II clinical trials with others in pre-clinical development. In addition to its proprietary research programmes, Astex’s productivity in lead discovery has been endorsed through numerous partnerships with major pharmaceutical companies, including AstraZeneca, Bayer-Schering, Boehringer Ingelheim, GlaxoSmithKline, Novartis and Johnson & Johnson. For further information on Astex please visit the Company’s website at www.astex-therapeutics.com

Avita Medical info.eu@avitamedical.com www.avitamedical.com Tel: 01223 341150 Fax: 01223 341170 Terrington House, 13-15 Hills Road, Cambridge CB2 1NL

A Avita Medical’s products are in the high growth, rapidly developing fields of Respiratory and Regenerative Medicine. Regenerative Medicine: Avita develops and distributes autologous tissue-engineered products for the treatment of a wide range of wounds, burns, scars and skin defects. Avita’s patented and proprietary tissue-culture and harvesting technology provides unique and innovative treatment solutions using a patient’s own tissue to enhance healing rates, reduce scar formation and reintroduce pigmentation into the skin. ReCell (www.recell.info) is a stand-alone, rapid, point-of-care cell harvesting device that enables surgeons to treat skin defects using the patient’s own cells, accelerating the healing process, minimizing rejection and eliminating scarring. The procedure is performed on site, takes approximately 45 min to perform and requires no laboratory or specialized surgeons. ReCell has been designed for use in a wide variety of plastic, reconstructive, burn and cosmetic procedures. ReCell is being evaluated for cost-effectiveness at 10 hospitals in France as part of a medico-economic study Funded by the French Government. Respiratory Medicine: Avita commercializes innovative medical technologies for improved medication delivery and adherence in patients suffering from chronic respiratory diseases. The company manufactures and sells a range of spacers for the paediatric, adolescent and adult market and is the leading provider of spacers in Australia. The Company has recently implemented a major restructuring which has included introduction of a new management team, reduction in headcount, elimination of extraneous R&D costs, and improvements in manufacturing efficiencies. Brief development plans and/or business plan: Avita Medical has put in place a focused strategic plan built on five key components: - Drive sales in key markets with regulatory approvals in place, working through established distributors and where appropriate, creating a direct sales presence; - Implement ‘continuous improvement’ models in operations and manufacturing to improve efficiencies and maximize margins - Tight management of working capital - Obtain regulatory approval for current products in key markets to ensure access to global economies; - Enhance product portfolio and expand applications of intellectual property through acquisitions and partnering.

info@babraham.co.uk www.babraham.com Tel: 01223 496269 Babraham Research Campus, Cambridge CB22 3AT

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Babraham Research Campus Ltd Derek Jones

The Babraham Research Campus, home to both world-class academic research and commercial biomedical companies, has established itself as one of the UK’s leading enterprise hubs of bioscience innovation. Situated on a 450 acre estate six miles south of Cambridge, the campus has an ideal geographical location at the heart of the Cambridge biomedical cluster, close to many world-leading academic research centres such as the MRC Laboratory of Molecular Biology (LMB), the Wellcome Trust Sanger Institute, Cancer Research UK and the University of Cambridge. The campus Bioincubator offers bespoke, state-of-the-art research and development facilities, scientific support services for bioventures at any stage in the business development cycle and supports the full spectrum of science from R&D to commercial realisation. Companies have access to the Technology Development Laboratory, set up by BBT as a place to accelerate the translation of early stage concepts in the life science and biomedical fields. BBT also has the responsibility for Knowledge Exchange of the Institute’s research, facilitating industry collaborations, patents and licensing agreements.

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Beckman Coulter Genomics Liz Bland EBland@beckman.com www.beckmangenomics.com

Beckman Coulter Genomics is the preeminent provider of genomic services and nucleic acid purification products, serving life-science researchers and the pharmaceutical industry throughout the world. By providing technical expertise, combined with personalized service, Beckman Coulter Genomics delivers the highest quality data, robust analyses and innovative thinking.

Tel: 01279 873837 Hope End, Takeley, Essex CM22 6TA

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Bicycle Therapeutics Limited Dr John Tite johntite @bicycletherapeutics.com www.bicycletherapeutics.com Tel: 01223 497390

Bicycle Therapeutics is a biotechnology company developing a novel technology for the creation of a new generation of biotherapeutics. The Bicycle technology utilises biological selection techniques to select and optimise peptides with high binding affinities which are constrained by an organo-chemical scaffold. This enables the creation of novel molecules which combine many of the desirable features of small molecules and biopharmaceuticals. The technology is based on the work performed at the MRC Laboratory of Molecular Biology in Cambridge by the scientific founders of the company, Prof. Christian Heinis and Prof. Sir Gregory Winter and is based at the Babraham Research Campus in Cambridge, U.K.

Meditrina Building, Babraham Research Campus, Cambridge CB22 3AT

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www.onenucleus.com

BioFocus Dr Richard Gordon

B C D E

info@glpg.com www.biofocus.com Tel: 01799 533500 BioFocus, Chesterford Research Park, Great Chesterford, Saffron Walden, Cambridge, Essex CB10 1XL

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www.bio.org Tel: 00120 28570244 Fax: 00120 28570237 1201 Maryland Avenue, SW Suite 900, Washington DC 20024 USA

BIO members are involved in the research and development of innovative healthcare, agricultural, industrial and environmental biotechnology technologies. Corporate members range from entrepreneurial companies developing a first product to Fortune 100 multinationals. We also represent state and regional biotech associations, service providers to the industry and academic centers. Visit the BIO Member Directory to browse BIO members and Web site links as well as BIO state and international affiliates. Member services include: * Federal and state advocacy on issues affecting the industry * A dozen or more investor and partnering meetings throughout the year, with discounts for members * Communications services that disseminate information about the benefits of biotechnology * BIO Business Solutions discounts for a variety of goods and services Specific issues may have changed over the years, but our core mission of fostering biotechnology innovation through advocacy, business development and communications remains the same. BIO produces the annual BIO International Convention, the world’s largest gathering of the biotechnology industry. The BIO International Convention attracts more than 20,000 attendees from around the world including more than 500 members of the international press. Convention attendees hear from global biotechnology leaders, learn about the latest biotech innovations and network with their peers from established and emerging biotech companies, research institutions, service providers and biotech hubs. BIO also produces a series of industry-leading investor and partnering meetings held around the world.

Biotica Technology Ltd info@biotica.com www.biotica.com

Tel: 01799 532920

Chesterford Research Park, Little Chesterford, Saffron Walden CB10 1XL

• Integrated drug discovery: conducting gene-to-candidate discovery programs using multidisciplinary teams • Target discovery: identifying novel targets using human primary cells • Assay development and screening: compound screening using tailored biochemical and cellular assays • Natural products: hit finding and lead generation from 8,000 fungal and 15,000 actinomycete strains. • Structural biology: revealing protein-drug interactions by X-ray crystallography. • Fragment-based drug discovery: label-free binding, high concentration biochemical assay, protein/ ligand crystallography and NMR technologies. • In silico drug discovery: accelerating drug discovery using computational technologies • Medicinal chemistry: designing and synthesizing novel drug candidates • ADME/PK: performing comprehensive ADME and pharmacokinetics • Compound libraries: accessing synthetic and natural product compound libraries for high-throughput screening • Compound management: acquiring, managing, controlling quality and distributing client screening collections

Biotechnology Industry Organization (BIO)

BioFocus offers a comprehensive suite of discovery products and services. These are available separately or as an integrated drug discovery solution, backed by a centralized project management system.

Fax: 01799 532921

Biotica is a Cambridge (UK) biotechnology company focused on identifying novel therapeutics based on polyketides. The company uses its proprietary biosynthetic engineering platform to identify novel polyketides, with improved pharmaceutical benefits, which could not be made using medicinal chemistry approaches. The company has implemented partnerships based on differentiated compounds derived from its technology platform, including the following: Pfizer and Biotica are developing novel analogs of the immunosuppressant drug, rapamycin, in new indications. GSK and Biotica are collaborating to discover and develop novel erythromycin macrolides for treatment of inflammatory disease. There are more than 40 marketed polyketide therapeutics, including the statins, erythromycin, rapamycin and FK506. Six polyketide drugs have each achieved annual sales in excess of $1 billion. Polyketides are a successful drug class because they have diverse and complex chemical structures, resulting in important biological properties which are not attainable using synthetic small molecules. Biotica has developed a competitive advantage in the discovery of polyketide therapeutics. The company’s business model is to integrate with partners that have extensive therapeutic biology and other complementary capability. Biotica’s approach represents a transformational opportunity to discover a new generation of engineered polyketide therapeutics.

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Cambridge Research Biochemicals info@crbdiscovery.com www.crbdiscovery.com Tel: 01642 567180 Fax: 01642 567181 10 Belasis Court, Belasis Hall Technology Park, Billingham Cleveland S23 4AZ

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Cambridge Research Biochemicals (CRB) celebrates 30 years of providing custom-made research tools to the Life Science community. The company, founded in 1980 is the second oldest peptide company in the world and specialises in everything peptide from design, synthesis, modification and labelling. We generate target specific antibodies to novel proteins and their peptide surrogates. Our chemical expertise is further applied to fluorescent labelling of peptides, antibodies and proteins and we can advise on appropriate fluorescent dyes for FRET and other fluorescence based applications. Our business works in partnership with other complementary specialist businesses or research institutes to extend our portfolio to offer: unique fluorescent dyes (Cyanagen, Italian partner), monoclonal antibody production and chemistry services (Babraham Bioscience Technology, Cambridge), Radiolabelling (RC-Tritec, Switzerland) and PNA synthesis (Panagene, South Korea). CRB enjoys longstanding relations with top ten pharmaceutical companies and world renowned research institutes. In 2009, CRB was granted EC support of 196,400 Euros as a contributing SME partner in the FP7 BIOSCENT project for providing peptide design and synthesis expertise to develop self-assembling peptides within the context of biomaterials for heart patches. This followed shortly after a Capital Expenditure programme and the support from One North-East Development Agency for 35% towards funding. The company is privately owned by two female directors who were winners of the North-East Women Entrepreneur Awards, for the Innovation through Technology category.

Cambridge Theranostics Ltd info@cambridgetheranostics.co.uk www.cambridgetheranostics.co.uk Tel: 01223 497130 Fax: 01223 497133 Meditrina Building (260), Babraham Research Campus, Babraham Cambridge, Cambridgeshire CB22 3AT

Cambridge Theranostics has identified a new mechanism of atherogenesis, caused by a certain class of catalytic antibodies that cross-react with the host serum lipoproteins and cause their peroxidation. We have named these catalytic antibodies ‘AtheroAbzymes’. We show that the presence of these AtheroAbzymes correlates with the level of stenosis of coronary and/or cerebral arteries and with the severity of angina, and that this process is active in most cardiovascular patients.s Cambridge Theranostics has developed a new product Ateronon®/TM that inhibits these atherogenic antibodies. Ateronon will be sold as a prescription medical food in the US, and as a health supplement with medical claims in Europe. Cambridge Theranostics also developed the AtheroAbzyme®/TM ELISA tests which support the administration of Ateronon: identification of patients or asymptomatic individuals with active atherogenesis and monitoring and optimisation of their treatment CTL has clinical research partners in the UK, Russia, USA and Europe and works with major corporations to develop, manufacture and market it products.

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Cantab Biopharmaceuticals Ltd Dr Jim Mills, CEO jim.mills@cantabbio.com www.cantabbio.com Tel: 01223 423413 150-155 Cambridge Science Park, Milton Road, Cambridge CB4 0GN

Cantab Biopharmaceuticals Ltd (CBL) is a drug development company focused on the development of “biosuperior” products. Cantab is based in Cambridge, UK at the heart of the largest biotech cluster in Europe. The company uses its extensive experience in biopharmaceutical discovery, process development and GMP manufacturing to expedite the development of biosuperiors from inception through clinical development. The strategy of the company is to add value to previously marketed, off-patent, biologics by applying cutting-edge technologies that address suboptimal characteristics of the marketed product. Particular areas of drug characteristics that Cantab seek to improve upon are product presentation and stability, pharmacokinetics, pharmacodynamics, immunogenicity and drug delivery.

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Cellzome Limited Jane Dancer jane.dancer@cellzome.com www.cellzome.com Tel: 01799 532800 Cellzome Limited, Chesterford Research Park, Little Chesterford, Cambridge CB10 1XL

Cellzome is a privately-owned drug discovery and development company, and a leader in the use of chemical proteomics technologies to identify a new generation of drug candidates for the treatment of inflammatory and other important diseases. Our pipeline of small-molecule therapeutics is driven by Kinobeads™ and Episphere™, proprietary technologies for screening and profiling kinases and epigenetic targets in their physiological context. Our goal is to identify oral therapeutics for inflammatory diseases and to leverage our Kinobeads™ and Episphere™ platforms in all indications through partnerships with pharmaceutical companies. Cellzome has already established significant kinase and epigenetics collaborations with GSK in immuno-inflammation.

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Coherent Logic Ltd info@coherentlogic.com www.coherentlogic.com 2nd Floor, 145-157 St John Street, London EC1V 4PY

Our goal is to help life sciences organisations in the UK move from the desktop to the enterprise. We accomplish this by focusing on key areas of software development that are critical to keeping life sciences businesses competitive, agile, and able to proactively plan for change rather than reacting to change in the market - these include enterprise software application development, service-oriented software development, and business process management and workflow solutions.

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Crescendo Biologics Amanda Bettison

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info@crescendobiologics.com www.crescendobiologics.com Tel: 01223 497140 Meditrina Building 260, Babraham Research Campus, Cambridge CB22 3AT

Crescendo Biologics is a Cambridge-based company whose aim is to deliver next-generation antibody therapeutics based on novel class-leading platforms. The company is focussed on developing a transgenic mouse platform for in vivo generation of human, high-affinity, soluble, VH antibody fragments. These are the smallest fragments that retain antibody binding and have many desirable properties as potential therapeutics. Crescendo will utilise this platform for product development of inhouse targets or in partnership with other companies. Crescendo is led by a management and Board with exceptional experience in the antibody field and the biotechnology sector, backed by a syndicate of leading life science investors.

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Cresset BioMolecular Discovery Ltd info@cresst-bmd.com www.cresst-bmd.com Tel: 01707 356120 Fax: 01707 356118 BioPark Hertfordshire, Broadwater Road, Welwyn Garden City, Hertfordshire AL7 3AX

While conventional modelling approaches rely on the atom and bond representations of compounds, Cresset’s field technology provides a powerful ‘protein’s view’ of the key molecular features required for biological activity. Furthermore, using molecular field patterns to compare molecules enables a robust structure-independent method of identifying novel chemical classes that can take a project into new intellectual property space. This technology is especially valuable for certain classes of receptors such as GPCR and ion channels, which are highly valued by the pharmaceutical industry but which lack sufficient X-ray crystallographic structures to allow easy molecular design. Cresset has a global client base which includes six major pharma companies and more than twenty biotechnology companies. Access to Cresset’s field technology is currently through three business models: 1) FTE-based Projects Hit-finding, lead switching - >80% success rate; 2-3 week time frame Lead optimisation Library design 2) Technology Development Customised solutions incorporating Cresset’s Field Technology 3) Software Leasing FieldScreen - for ligand-based virtual screening without structural prejudice. FieldTemplater - generates bioactive conformation hypotheses enabling ‘structure based drug design’ on GPCR’s and Ion channels - Free demo downloadable from website FieldAlign - decipher complex SAR - Free demo downloadable from website XedeX creates diverse conformations for any molecule based on our XED force field.

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Cyclofluidic Ltd www.cyclofluidic.co.uk Tel: 01707 358673 BioPark, Broadwater Road, Welwyn Garden City, Hertfordshire AL7 3AX

Cyclofluidic is a young technology company integrating chemistry and biology for drug discovery application. We are developing an integrated chemical synthesis through biological assay platform utilising microfluidic technologies to dramatically improve the efficiency of structure activity data generation for pharmaceutical research. Small molecule drug discovery typically involves many iterations of synthesis of novel molecules and their characterisation both chemical and biological in an iterative manner. In a typical large pharmaceutical company each iteration will take a minimum of a couple of weeks. In contrast the platform Cyclofluidic is developing will be capable of undertaking the entire process in just a couple of hours. This dramatic improvement in efficiency will enable not only faster discovery but also provides greater oopportunity for the exploration of more areas of chemical space with the potential to improve the quality of clinical candidates. Alongside research and development of the integrated platform Cyclofluidic is also exploring an open access laboratory for microfluidics in chemistry and biology and would be interested in talking to companies who have an interest in this rapidly developing arena. Cyclofluidic shareholders are Pfizer and UCB with additional funding through a Technology Strategy Board grant.

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Cytocell Technologies probes@cytocell.com www.cytocell.com Tel: 01223 294048 Units 4 Technopark, Newmarket Road, Cambridge, Cambridgeshire CB5 8PB

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A small medical device manufacturing company, recently been acquired through a management buy-out from Cytomyx Holdings plc. Manufacturers of innovative screening solutions for a variety of genetic disorders using Fluorescence in situ Hybridisation as a core technology. Current strengths are in the routine cytogenetics field, though new developments based on a proprietary delivery platform for FISH probes are aimed at the Oncology market, specifically in Haematology.

Domainex Ltd www.domainex Ltd Tel: 01993 201801 Fax: 01993 200401 324 Cambridge Science Park, Milton Road, Cambridge CB4 OWG

A Domainex offers services including highly experienced computational and medicinal chemistry and a unique patented technology called CDH. Our unique LeadBuilder technology for finding in a highly cost effective manner robust developable hits. LeadBuilder has been used many times for clients in the academic or biotech areas with great effect. Our medicinal chemistry expertise is based upon a team of highly experienced medicinal chemists based in Cambridge with a history of working for leading European Pharma and Biotech. We specialise in tackling a broad range difficult targets for drug discovery, including peptidomimetics. Combinatorial Domain Hunting or CDH is a unique patented technology conceived by Prof Laurence Pearl’s team of leading structural biologists and is specifically aimed at expressing protein targets for drug discovery that can not be expressed by other approaches. CDH has been applied to targets from many leading Pharma. Domainex also has its own drug discovery pipeline. Domainex’s lead project is IKK epsilon which is in lead optimisation for breast cancer. Domainex also has a pipeline of lysine methyl transferases (KMTs) all targeted at cancer. Our unique CDH technology has been applied to a number of KMTs with the aim of producing unique x-ray structures and assays.

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Domantis Limited Domantis develop a range of platform technologies for the in vitro evolution and engineering of recombinant proteins. The field of recombinant proteins is showing immense potential and is expected to yield both new medicines together with vital diagnostic and proteomic tools.

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Eagle Genomics Ltd info@eaglegenomics.com www.eaglegenomics.com Tel: 01223 654481 Fax: 01223 281125 Babraham Research Campus, Babraham, Cambridge, Cambridgeshire CB22 3AT

Open-source bioinformatics software gives you unparalleled access to the very latest algorithms, data and techniques to use in your R&D. However, it can be hard to obtain timely technical support when things don’t go quite to plan. This can cost you time and money from lost productivity. Eagle Genomics provides that support. For a range of open-source bioinformatics technologies we guarantee our response times under a Service Level Agreement and provide you with fixes and customisations. This saves you time and effort, and helps minimise the cost of your projects. Our team of high calibre developers and researchers is drawn from both industry and academia with over 30 years combined experience in bioinformatics and software development. Eagle is extremely flexible in the ways we can work with our customers. Whether you are a big pharma or a university research group, a CRO or a small biotech startup, we can provide exactly what you need to make the most of your investment in open-source bioinformatics.

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Essen BioScience Ltd ics@essen-instruments.com www.essen-instruments.com Tel: 01707 358685 BioPark, Broadwater Road, Welwyn Garden City, Hertfordshire AL7 3AX

Essen Bioscience is a leading instrument and service provider in the life science research field, specialising in innovative cell-based assays. Products invented by Essen personnel include the first high-throughput cell-based assay platform, FLIPR; the first high-throughput planar electrophysiology platform on the market, IonWorks and the first live-cell imaging system to fit inside a standard cell culture incubator, IncuCyte. Our discovery services division deploys these and other technologies in providing bespoke solutions for our pharma, biotech and academic client base.

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Genzyme research.cambridge@ genzyme.com www.genzyme.co.uk

Tel: 01440 703522

12 Rookwood Way, Haverhill, Suffolk CB8 8PB United Kingdom

Fax: 01440 716269

Genzyme Europe Research is Genzyme’s first dedicated research facility in Europe based on the Cambridge Science Park. The science team is currently focused on Antibody Technology. Additional complementary therapeutic technologies will be imported to increase the repertoire of the team as opportunities arise. The team is using phage display technology to create reagent antibodies for target validation purposes as well as candidate therapeutic antibodies to targets of interest. Both single chain variable domain (scFv) phage display libraries, as well as FAb phage libraries are being employed. A close working relationship exists between the Cambridge Team and the Framingham (MA) based Molecular Immunology and New Protein Therapeutics Groups. Targets of interest to the Oncology, IMD and Renal Biology Portfolios have been identified and efforts are underway to create single chain and FAb fragments to these targets. Following attainment of proof of concept in pre-clinical models, a major goal for the Cambridge team will be the use of Antibody Technology to create candidate therapeutic antibodies for use in clinical trials.

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Gilead Sciences Ltd www.gilead.com Tel: 01223 897300 Fax: 01223 897282 Granta Park, Abington, Cambridge, Cambridgeshire CB21 6GT

Gilead Sciences is a research-based biopharmaceutical company that discovers, develops and commercialises innovative medicines in areas of unmet need. With each new discovery and experimental drug candidate, we seek to improve the care of patients suffering from life-threatening diseases. Gilead’s primary areas of focus include: antivirals (such as HIV/AIDS and chronic hepatitis), cardiovascular conditions (such as pulmonary arterial hypertension and resistant hypertension) and respiratory diseases (such as influenza and cystic fibrosis). Gilead Sciences has grown from one facility in California to 19 sites with more than 2,900 employees in 15 countries across North America, Europe and Australia. Outside of North America, we have offices in 15 European countries and Australia. Our European headquarters are located in Stockley Park, outside London, in the United Kingdom. Gilead plans to open additional commercial operations in Europe in the coming months. We have created a network of exclusive distributors that work to ensure access to our commercial products in many parts of the world. These distributors currently support Gilead products in more than 40 countries across Eastern Europe, Scandinavia, the Middle East, Asia, Africa and Latin America

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Horizon Discovery Ltd www.horizondiscovery.com Tel: 01223 655580 Fax: 01223 862240 Building 7300 (7340), IQ Cambridge, Waterbeach, Cambridge, Cambridgeshire CB25 9TL

Central to realizing this ambition is the deployment of a proprietary gene-engineering technology called GENESIS that enables any endogenous gene in a human cell-line to be altered quickly, reliably and without introducing unwanted and confounding genotypes and/or phenotypes. Using GENESIS, a wide panel of genetically-defined and patient-relevant X-MAN (Mutant And Normal) cell models have been developed and these are fast being adopted by academic and industry leaders to find and tailor the ‘right drugs’ to the ‘right patients’ based upon the unique genetic mutations that define their disease.

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Huntingdon Life Sciences strat.dev@ukorg.huntingdon.com www.huntingdon.com Tel: 01480 892173 Fax: 01480 892205 Woolley Road, Huntingdon, Alconbury PE28 4HS

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Huntingdon Life Sciences has considerable experience in supporting the development of biotechnology-derived pharmaceuticals, having been involved in the safety testing of these products since they were first introduced in the early 1980s. We have worked with a large number of companies in developing a diverse range of products including; recombinant proteins, monoclonal antibodies, vaccines, gene and somatic cell therapy, antisense products and conventional biologics. Our services include, - multiple species studies including transgenics histology / immunocytochemistry laboratory to assess cross-reactivity of monoclonal antibodies with human and animal tissues - methods to detect biopharmaceuticals and antibodies raised to them in biological matrices methods to assess the effects of biopharmaceuticals on immune status and function - in vitro and in vivo models to assess pharmacology and efficacy - range of safety pharmacology models - range of reproductive toxicity studies - range of genotoxicity studies

Hypoxium

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Illumina Ltd info@illumina.com www.illumina.com Tel: 01799 532303 Chesterford Research Park, Little Chesterford, Saffron, Walden CB10 1XL

At Illumina, our goal is to apply innovative technologies and revolutionary assays to the analysis of genetic variation and function, making studies possible that were not even imaginable just a few years ago. These studies will help make the realization of personalized medicine possible. With such rapid advances in technology taking place, it is mission critical to have solutions that are not only innovative, but flexible, scalable, and complete with industry-leading support and service. As a global company that places high value on collaborative interactions, rapid delivery of solutions, and prioritizing the needs of its customers, we strive to meet this challenge. Illumina’s innovative, array-based solutions for DNA, RNA, and protein analysis serve as tools for disease research, drug development, and the development of molecular tests in the clinic. leading-edge products and services Illumina has developed a comprehensive line of products that address the scale of experimentation and the breadth of functional analysis required to achieve the goals of molecular medicine. Our offering includes leading-edge solutions for: SNP genotyping Copy number variation DNA methylation studies Gene expression profiling Lowmultiplex analysis of DNA, RNA, and protein Our products and services are used by a broad range of academic, government, pharmaceutical, biotechnology, and other leading institutions around the globe.

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Isogenica Ltd www.isogenica.com Tel: 01799 533685 Fax: 01799 531940 The Mansion House, Chesterford Research Park, Little Chesterford CB10 1XL

“Isogenica specialises in providing protein engineering and molecular evolution services using its core technology, “CIS display”, to pharmaceutical and biotechnology companies for the rapid discovery, identification and design of new peptide polypeptide and antibody lead compounds. CIS display can quickly construct polypeptide libraries of unprecedented size and complexity in vitro, without the need for cloning. A library of up to a hundred trillion different clones can be easily generated in a few hours and quickly processed so that better products and motifs can be selected in just a few days. CIS display technology has provided hits and information against a wide range of targets and has advantages over alternative technologies. The technology is adaptable for the display of different proteins and licences are available for scFv and other polypeptide scaffolds. Isogenica has secured more than a dozen partnering and licensing deals to date and is seeking further collaborations with companies actively engaged in developing peptide and polypeptide systems”.

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Kymab Limited www.kymab.com Meditrina Building, Babraham Research Campus, Cambridge CB22 3AT

Kymab is using embryonic stem cell technology to develop its KymouseT platform, which encompasses the entire diversity of the B lymphocyte component of the human immune system. This will allow the discovery of highly selective, potent and well-tolerated monoclonal antibody-based biopharmaceuticals. These new drugs will include best-in-class antibodies directed against clinically precedented drug targets and first-in-class drugs against novel targets.

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Lab21 info@lab21.com

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www.lab21.com Tel: 01223 395450 184 Cambridge Science Park, Milton Road, Cambridge CB4 0GA

Lab21 is a rapidly growing global provider of state-of-the-art diagnostic products and services, supporting blood bank screening, medical diagnostics and drug discovery. Its customers include international healthcare providers, pharmaceutical and biotechnology companies. The product division of the Company manufactures immunodiagnostic kits and reagents that are distributed into 110 countries globally through both direct and indirect channels. A key focus is infectious diseases for the blood banking market, with assays available for syphilis, CMV and malaria. The service division has a growing test portfolio providing companion diagnostics and high technology molecular assays for the growing integration of personalised medicine into healthcare. These services are currently in infectious diseases, oncology, virology and pharmacogenetics areas with emerging interests in cardiovascular and metabolic disease. Lab21 has 5 sites in the UK with two highly accredited reference laboratories and 3 immunodiagnostic manufacturing sites. The Company also has two sites in the State of South Carolina for its US operations.

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London Technology Network www.ltnetwork.org Argyle House, 29-31 Euston Road, London NW1 2SD

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Lonza Biologics Plc

Philippe Stas, Head Applied Protein Services, Lonza Biologics

appliedproteinservices @lonza.com www.lonza-aps.com

Tel: 01223 895102 / 01223 895100

Lonza Biologics plc, Granta Park, Great Abington, Cambridge CB21 6GS

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Lonza’s Applied Protein Services division (APS) brings quality-by-design methodologies to the development of biopharmaceuticals to produce better and safer molecules. Our team integrates unique immunogenicity and stability risk assessment and re-engineering capabilities for the development of better and safer biotherapeutics. Our technologies have been extensively validated in different molecules with remarkable results. Lonza-APS offers comprehensive services on: • In silico and in vitro T-cell Epitope & Immunogenicity assessment • In silico Protein Aggregation & Stability assessment and avoidance • In silico Protein Engineering & Stabilization • Antibody Humanisation • In vitro Protein Design Validation (productivity, activity and stability) • Rapid supply of sub-gram quantities of recombinant proteins

Medivir AB Paul Wallace PhD, VP and head of business development paul.wallace@medivir.com www.medivir.com Tel: 01799 532100 Medivir AB, Chesterford Research Park, Little Chesterford, Essex CB10 1XL

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Lonza is one of the world’s leading suppliers to the pharmaceutical, healthcare and life science industries. Its products and services span its customers’ needs from research to final product manufacture. Lonza is the global leader in the production and support of active pharmaceutical ingredients both chemically as well as biotechnologically.

One Nucleus Directory 2011

Medivir develops pharmaceuticals against major diseases, focusing on infectious disease caused by viruses. We are conducting our first product launch in 2010, a pharmaceutical fully developed ourselves against labial herpes, to be launched in Europe and US with partners GSK and Meda. We have a significant presence in HCV addressing different approaches, including TMC-435, a protease inhibitor, which has completed phase IIb with partner Tibotec/J&J. Our R&D targets specific enzymes, such that we have projects outside our core segment: in OP, OA and metastatic bone disease. Medivir has several partnerships with pharma/biotech companies and is quoted on NASDAQ OMX Stockholm.

Melbourn Scientific Ltd Martin Westcott martin.westcott @melbournscientific.com www.melbournscientific.com

Melbourn Scientific are a Cambridge based provider of world leading contract analytical, formulation and product development services for the pharmaceutical, biopharmaceutical, biotechnology and healthcare industries. From lead optimisation to finished product testing our experienced team offer a extensive support including formulation/ reformulation projects and product development on a wide range of pharmaceuticals, biopharmaceuticals, drug delivery devices and medical devices.

Tel: 01763 261648

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Saxon Way, Melbourn, Cambridgeshire SG8 6DN

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Norwich Bio-Incubator Dr Jon Carter j.carter@norbio.com www.norbio.com Tel: 01603 450950

The Norwich Bio-Incubator delivers its mission by offering a combination of accommodation, business development and scientific services. Located at the John Innes Centre on the Norwich Research Park the Norwich Bio-Incubator is part of one of the largest clusters of world leading life science research. Other institutions on the Norwich Research Park include the Institute of Food Research, Norfolk and Norwich University Hospital, Sainsbury Laboratory and the University of East Anglia who together employ more than 6,500 research staff. The accommodation available includes modern purpose built office and wet laboratories which all benefit from extensive support infrastructure, dining facilities, free car parking and broadband internet access. A wide range of business support and incubation services are available both from the Norwich Bio-Incubator directly and through its extensive network of experts, specialists and business support service providers. Tenants of the Norwich Bio-Incubator are able to access a wide range of scientific support services including state of the art genomics and proteomics and specialist plant and microbial growth facilities. The Norwich Bio-Incubator works with prospective tenants to develop the service package their company requires to maximise its potential. To find out how the Norwich Bio-Incubator can assist you develop your business please call or email Dr Jon Carter (01603 450950, j.carter@norbio.com)

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Novacta Biosystems Limited Jane Whitrow PhD FCA VP Corporate Affairs jane.whitrow@novactabio.com www.novactabio.com Tel: 01707 356130 Fax: 01707 356131 Novacta Biosystems Limited, BioPark Hertfordshire, Broadwater Road, Welwyn Garden City, Hertfordshire AL7 3AX

Novacta is an R&D focused company developing new anti-infectives and providing services to the fine chemical & industrial biotech sectors.

Our therapeutics division is focused exclusively on the discovery and development of novel antibacterial agents to treat new and emerging infectious diseases, particularly those caused by antibiotic resistant â&#x20AC;&#x2DC;super-bugsâ&#x20AC;&#x2122;. Our lead product for the treatment of C.difficile is currently undergoing preclinical safety assessment.

Our services division works with customers in the pharma, agrichem, industrial biotech, flavours & fragrances and cosmetics sectors. Our expertise includes:

1) Microbial metabolic engineering 2) Biocatalysis 3) API/agrochemical metabolites

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Novus Biologicals Ltd novus@nobusbio.com www.novusbio.com Tel: 01223 426001 12 Cambridge Science Park, Milton Road, Cambridge CB4 0FZ

The mission of Novus Biologicals, Ltd. is to accelerate scientific discovery by developing and marketing unique products in the forefront of science. Novus Biologicals was organized to provide the biological research community with a mechanism for commercializing unique biological materials. We also focus on continually monitoring scientific trends and supplying materials to serve these trends. Novus Biologicals Ltd. core focus is the serve the research community of the United Kingdom and the European Union.

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Origin Sciences Limited Colonix Medical Limited is a UK based organisation with offices in mainland Europe and the U.S.A. The company is dedicated to researching, developing and commercialising new products for the early and accurate detection of bowel disorders, in particular colorectal cancer. Many thousands of hours of research by our own research and development team, combined with our clinical collaborators have enabled the launch of our first commercial IVD based product, ColoGenixTM Pre-View.

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ColoGenix™ Pre-View is an innovative, minimally invasive and inexpensive test that can be used as a colonoscopy qualification tool for symptomatic patients. This product is the first of a series of tests to be released. All of these products utilise the Colonix Cell Sampling device. This is an operator and patient friendly device that has been carefully designed and perfected with the assistance of many clinicians. The final product can be operated by a nurse and the virtually painless cell collection procedure takes less than five minutes to perform.

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As a company Colonix is interested in talking to global distributors, potential partners and customers with a view to driving this unique product forward.

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Pathology Diagnostics Ltd www.pathologydiagnostics.com

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Services include tissue distribution, tissue microarray manufacture, laboratory processing, immunohistochemistry, expert diagnostic analysis and delivery of detailed reports to clients for their commercial needs. From target identification to clinical trials, we provide a unique breadth of scienctific and medical laboratory and diagnostics expertise. Our team of experienced accredited pathologists and laboratory personnel ensures high standard of reporting of studies, and GLP compliance, ensuring quality results and peace of mind. Our additional core strengths are our quality consistency and reliability, fast turnaround times, complete confidentiality and competitive pricing. For further information, please visit our website: www.pathologydiagnostics.com. We are always willing to discuss projects with new clients in the UK and overseas.

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Pfizer Limited Nic Bowman

Pfizer is a leading pharmaceutical company, operating in 180 countries worldwide.

nic.bowman@pfizer.com

Pfizer employs over 4,000 staff in various sites over the UK, including two sites in Cambridge that are dedicated to the development of drug delivery devices and the research of regenerative medicines. Also, the UK is the location for Pfizer’s’ European R&D HQ at Sandwich in Kent.

www.pfizer.co.uk

Pfizer Ltd, Granta Park, Great Abington, Cambridge CB21 6GP

Pathology Diagnostics Ltd. is an independent Cambridge-based company delivering specialist tissue laboratory and diagnostic services to clients to support the development of novel drugs and companion diagnostics. We aim to provide a one stop solution to all your human tissue diagnostic needs from pre-clinical development to clinical trials. Serving major pharmaceutical, biotech and contract research organisations, tissue banks and academia, we provide a complete solution for novel drugs and companion diagnostics from early phase target discovery to clinical trials.

Tel: 01304 616161

Pfizer’s current key pharmaceutical products include – Lipitor, Lyrica, Celebrex, Viagra, Effexor, Xalatan/Xalacom, Novasc, Enbrel and Zyvox.

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Pfizer Regenerative Medicine www.pfizer.com Tel: 01304 643485 UCB Building, Granta Park, Cambridge CB21 6GS

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Pfizer Regenerative Medicine will operate as one of Pfizer’s new small, independent research units to help it foster a biotechnology culture and environment.

Pharmorphix Jayne Williams info@pharmorphix.com www.safcglobal.com/ pharmorphix Tel: 01223 425105 250 Cambridge Science Park, Milton Road Cambridge, Cambridgeshire CB4 0WE United Kingdom

A SAFC Pharmorphix® is a world leading provider of solid form research services to the pharmaceutical and biotechnology sectors. Our experience coupled with our state of the art facilities, places Pharmorphix® at the forefront of pharmaceutical solid form research and development.

Our focus is to drive molecules in the clinic by understanding and modifying the physical properties of the drug substance to ensure patient benefit, rapid development and protection of intellectual property.

Pharmorphix’s® R&D support services include polymorph investigation, salt selection, physicochemical property determinations, pre-formulation profiling, co-crystallisation, classical chiral resolution and crystallisation studies.

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Phico Therapeutics Ltd info@phicotherapeutics.co.uk www.phicotherapeutics.co.uk Tel: 01223 496562 Fax: 01223 496563 Building 405, Babraham Research Campus, Babraham, Cambridge, CB22 3AT

Phico is a small biotechnology company developing a groundbreaking antibiotic platform technology known as SASPject. The technology is designed to target any harmful type of bacteria, including ‘superbugs’ such as MRSA and C. difficile. The technology utilises programmable delivery vectors to deliver genes encoding unique antibacterial proteins, SASP, to target bacteria. Phico’s first product, SASPject PT1.2 aimed at S. aureus, including MRSA, has completed a Phase I clinical trial. This product has shown rapid activity in culture against >200 clinical strains of S. aureus killing up to 99.9 % of MRSA bugs within 2 minutes. The technology is patent protected in the US, Europe, Japan and Australia, and pending in Canada. Each product is expected to have separate patent coverage with the PT1.2 product patent granted so far in the UK. Phico plans to licence PT1.2 post Phase II clinical trial and to license, post Phase I, its other products in development, including SASPjects targeted at C. difficile and a group of Gram negative bugs including E. coli/K. pneumoniae/P. aeruginosa. Phico has raised approximately £9 M to date, including a Strategic Translation Award for £1.03 M from the Wellcome Trust to fund the Phase I and II clinical trials with SASPject PT1.2.

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Population Genetics Technologies Ltd Dr Frank Massam frank.massam@popgentech.com www.popgentech.com Tel: 01223 497350 Babraham Research Campus, Cambridge CB22 3AT

Population Genetics Technologies Ltd (PopGenTech) has developed GenePooling© technology to characterise genetic variation in large populations, rapidly and cost-effectively. GenePooling© identifies novel genetic variants in candidate genomic regions that: (i) predispose individuals to disease, (ii) are useful for biomarker development for strati?ed clinical trials and personalised medicine and (iii) enable classification of pathogens for infectious disease. We tag individual genomes with unique DNA sequences, pool all genomes as a single mixture, and then extract and analyse candidate sequences in this population pool. Analysis together with clinical data allows direct hypothesis testing of candidate genes. From January 2011, PopGenTech will be offering GenePooling© as a service to pharmaceutical companies, CROs, and researchers studying the implications of genetic variation.

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ProMetic Biosciences Ltd sales@prometicbiosciences.com www.prometicbiosciences.com Tel: 01223 420300 Fax: 01223 420300 211 Cambridge Science Park, Milton Road, Cambridge CB4 0ZA

ProMetic Biosciences Ltd (PBL) is a wholly-owned subsidiary of Canadian-based ProMetic Life Sciences Inc., and since 1987 has pioneered the design, development and manufacture of affinity separation products and technologies. PBL specialises in synthetic affinity ligands - Mimetic Ligands™ - which are used by numerous companies making PBL a key supplier to the global life sciences industry. The chemical diversity of PBL’s synthetic ligand libraries allows application to almost any target protein. PBL’s bioseparation products are developed and manufactured in-house and the company is ISO 9001 accredited. PBL’s affinity technology may be applied to the capture of targeted proteins directly from biological source material, the separation of target protein from other components, or the capture of specific contaminants. Applications include the purification of: antibodies, antibody fragments, albumin, albuminfusion proteins, plasma proteins, glycoproteins, proteases and other recombinant proteins. PBL has also applied it’s technology to the capture and removal of prion proteins (vCJD) from blood, plasma and plasma-derived products. In partnership with the American Red Cross, PBL has developed the Prioclear™ range of prion binding adsorbents, applications of which include the revolutionary P-Capt® filter, a CE mark approved prion reduction device (developed in collaboration with MacoPharma SA) which provides a means of significantly reducing the risk of vCJD transmission by blood transfusion. Additionally, Prioclear™ adsorbents have been applied to plasma and plasma-derived products to improve prion safety margins and reduce the risk of vCJD transmission.

www.onenucleus.com

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Proximagen Robin Turner

www.proximagen.com Tel: 01223 497300

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Fax: 01223 496083

The company’s founders originate from a Pfizer Global Research & Development drug discovery team in what had previously been the Parke-Davis Neuroscience Research Centre. The founders, together with some key academic collaborators, created the company to exploit several opportunities in drug discovery as well as their world class “gene to lead” drug discovery capability. The company has well equipped modern laboratory and office facilities situated on the Babraham Research Campus. This location allows the company to forge links with a host of world class research groups based in the Cambridge area.

Minerva Building (250), Babraham Research Campus, Babraham, Cambridge, Cambridgeshire CB22 3AT

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Psynova Neurotech Barbara Baron barbara.baron@psynova.com www.psynova-neurotech.com Tel: 01223 421635

Psynova Neurotech is exclusively focused on the commercial development and exploitation of novel biomarkers for Neuropsychiatric and other mental illnesses. Building on 12 years of ground-breaking research by its founder Prof. Sabine Bahn, Psynova Neurotech is initially concentrating on Schizophrenia and Bipolar Affective Disorder. In 2010, our first product was launched in the USA by our partner Rules Based Medicine, Inc.; VeriPsych™ is the first and only blood test to aid a psychiatrist in the diagnosis of recent-onset schizophrenia.

St John’s Innovation Centre, Cowley Road, Cambridge CB4 0WS

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Quotient Bioresearch Ltd info@quotientbioresearch.com www.quotientbioresearch.com

Tel: 01638 720500

Newmarket Road, Fordham, Cambridge CB7 5WW

Fax: 01638 724200

Quotient Bioresearch provides specialist laboratory and clinical services focused on early phase drug development from discovery through to proof of concept. - Integrated preclinical and clinical DMPK with GMP chemistry/radiosynthesis - Bioanalytical sciences from the world’s leading sports drug surveillance laboratory Comprehensive microbiology for discovery and development of antimicrobials - Formulation development, GMP manufacturing and GCP Phase I clinic in the same facility With over 350 highly skilled scientists and facilities in Cambridgeshire, Northamptonshire, Nottingham, Edinburgh and Cardiff, Quotient Bioresearch has comprehensive capabilities and is the only drug development partner which provides a truly integrated service from discovery to proof of concept. This is demonstrated in our unique Synthesis-to-Clinic™ service providing carbon-14 labelled compounds through to pre-clinical metabolism studies and integrated 14C clinical programmes, supported by our purpose built bioanalytical and central laboratory facilities.

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Recombinant Antibody Technology Ltd Tel: 01223 497171

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Recombinant Antibody Technology Ltd. is specializing in the generation of large recombinant DNA constructs using YAC and BAC technologies. Currently, the company is working with Open Monoclonal Technology, Inc., a US based biotechnology company, on the generation of recombinant immunoglobulin loci for the generation of genetically engineered rats expressing antibodies with fully human idiotypes.

Selcia Limited contact@selcia.com www.selcia.com Tel: 01277 367000 Fax: 01277 367099 Fyfield Business and Research Park, Fyfield Road, Ongar CM5 0GS

A Selcia is a leading worldwide provider of contract research services in 14-C custom radiolabelling, integrated drug discovery and medicinal chemistry. Headquartered in a 2,500 sqm modern facility with a GLP analytical laboratory, in Ongar, Essex (UK). Selcia’s operating divisions are Selcia Radiolabelling a recognised international leader in 14-C custom radiosynthesis and Selcia Discovery which specialises in fragment-based drug discovery using a patented capillary electrophoresis screening platform – the CEfragTM Screen. Selcia supports clients from all continents including the pharmaceutical, biotechnology, crop-science, veterinary, chemical, household, personal care and nutrition sectors as well as academic institutions. Selcia Discovery - Integrated drug discovery - Fragment screening (CEfrag screen) - High quality fragment library - Lead discovery and lead optimisation - Medicinal chemistry Cell biology and screening - Help with grant applications - IP generation to optimise patent protection - R&D collaborations (FTE funding) Selcia Radiolabelling - 14-C Radiosynthesis - Radiolabelled API for clinical studies Compound storage, stock management - GLP certification - GLP NMR services - Synthesis of reference standards (process impurities, metabolites) - Comprehensive data package including NMR data and synthetic method With a passion for synthetic chemistry and a focus on personal service we build strong relationships with our clients and deliver to the highest standards.

www.senexis.com Tel: 01223 496160 Fax: 01223 496161 Babraham Research Campus, Babraham, Cambridge CB22 3AT

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Senexis Limited info@senexis.com

Senexis is a growing, small-molecule drug development company that is committed to revolutionising the treatment and diagnosis of diseases resulting from the inevitable process of ageing. Senexis is advancing a pipeline of novel treatments for diseases resulting from the toxicity of amyloid-like proteins. Our pipeline is currently focused on discovering potent and selective therapies for the treatment of Alzheimer’s diseases. Optimised lead compounds for Alzheimer’s disease have already shown pre-clinical efficacy in a variety of established models of memory and learning and are currently in development candidate selection studies. Senexis is actively seeking to enter into collaborations and licensing deals with established pharmaceutical and emerging biotechnology companies. Senexis plans to offer a balanced portfolio of pre-clinical or early clinical licensing opportunities to the pharmaceutical sector, particularly in the more costly areas of clinical development.

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Shire Pharmaceuticals Ltd www.shire.com Tel: 01256 894000 Fax: 01256 894704 Hampshire International Business Park, Basingstoke RG24 8EP

As one of the world’s leading specialty biopharmaceutical companies, Shire has emerged as a company fully focussed on a single purpose: to enable people with life-altering conditions to lead better lives. Shire HGT, a vastly experienced and highly dedicated business unit of Shire Pharmaceuticals Ltd, specialises in discovering and developing innovative treatments for rare genetic diseases such as Fabry disease, Hunter Syndrome, Gaucher disease, hereditary angioedema and metachromatic leukodystrophy. Products such as ELAPRASE for Hunter Syndrome, REPLAGAL for Fabry disease and FIRAZYR for hereditary angioedema are available in markets around the globe, with FDA and EMEA regulatory approvals for velaglucerase alfa for Gaucher disease expected in 2010. Shire HGT employs nearly 1000 people worldwide who work across range of research and development, production and commercial disciplines. Shire HGT has offices in Basingstoke, UK and Cambridge/Lexington, US and a network of offices and distribution channels throughout Europe, Middle East, Africa, South America, Canada and the Pacific Rim.

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Sphere Medical Ltd enquiries@spheremedical.com www.spheremedical.com Tel: 01223 875222 Fax: 01223 875201 Harshen Mill, Harston, Cambridge CB22 7GG

Sphere Medical develops highly innovative monitoring products to provide clinical and economic benefits in the critical care environment. The products, all of which are based on the company’s proprietary technology, allow minimally invasive, real time measurement of clinical chemistry parameters and therapeutic drug concentrations, giving healthcare professionals the information they require to more effectively manage therapy and optimise patient outcomes. Sphere Medical was founded in 2002 and is based in Cambridge, UK. Our focus is on the continuous improvement of critical care. Our vision is to lead the way in the provision of products that empower medical institutions with tomorrow’s technology today. Our purpose is to deliver real value to all of our stakeholders. Three major funding rounds raising over $30 million have enabled Sphere to grow and develop into one of the world’s leading medical device / diagnostic companies, winning a variety of awards including Frost & Sullivan’s Technology Innovation Award in the Field of Point-of-Care Technologies. Sphere is now working with world leading companies in a range of clinical areas to develop the next generation of critical care products incorporating Sphere’s unique micro-analyser platform.

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Stem Cell Sciences Ltd Dr Paul Bello (Site Head), Jo Kellet (Administration Manager) jo.kellet@stemcellsciences.com

www.stemcellsinc.com

Minerva Building 250, Babraham Research Campus, Cambridge CB22 3AT

Tel: 01223 499160

Stem Cell Sciences, a wholly owned subsidiary of StemCells, Inc., is applying its scientific and industry leadership in stem cell biology to discover, develop and commercialize game-changing therapeutics and enabling tools and technologies for use in stem cell-based research and drug discovery. The Cambridge branch is focussed on the manufacture and distribution our SC Proven range of specialty cell culture media and reagents enable the standardized and reproducible production and propagation of human and rodent pluripotent and tissue-specific stem cells.

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Takeda Cambridge Limited Linda Millett, HR and Communications Manager

Takeda Cambridge (TCB) is a drug discovery company specialising in identifying and validating innovative drug targets.

info@takedacam.com

TCB has established world-class target identification and validation capabilities. We have developed a promising pipeline of novel drug discovery targets and compounds in such key areas of unmet medical need as CNS disorders and metabolic-related diseases.

www.takedacam.com

Tel: 01223 477910

418 Cambridge Science Park, Cambridge CB4 0PA

Worldwide, Takeda develops, manufactures and markets a broad range of pharmaceutical products and strives towards better health for patients worldwide through leading innovation in medicine.

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TARRC (Tun Abdul Razak Research Centre) general@tarrc.co.uk www.tarrc.co.uk

Tel: 01992 585915

Brickendonbury, Hertford SG13 8NL

Fax: 01992 554837

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TARRC is the UK-based research and promotion centre of the Malaysian Rubber Board. TARRC’s Biotechnology Unit conducts research into aspects of plant genomics, molecular biology/genetics and proteomics of rubber and other tropical crops. A consultancy service is also offered. - Gene cloning and protein expression in plant or bacteria heterologous systems. - Generation of protein mutants for studies on stability and functionality. - Possibility of studying protein processing, maturation and targeting in vivo and in vitro. - Production of recombinant proteins in E. coli or plant systems eg. Arabidopsis thaliana and Nicotiana tabacum. - Protein purification from bacteria cultures or plant tissues and protein characterization. - Quantitative and qualitative analysis of total protein content using a ‘proteomic’ approach. - Measurement of stability and kinetics of protein-protein and protein-antibody interaction (Biacore system). - Genotyping using range of molecular markers – SNP, SSR, AFLP, RFLP etc. - Genetic mapping. - QTL mapping and Molecular Marker Assisted Selection (MAS); Molecular Marker Assisted Breeding (MAB). Sanger sequencing. - Sequence assembly and annotation using NG and Sanger sequencing data. Routine and specialized analytical techniques are available for nucleic acid and protein studies. Work on sequencing of the Hevea brasiliensis (natural rubber) genome is in progress.

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TiGenix www.tigenix.com Tel: 01223 496700 Byron House, Cambridge Business Park, Cowley Road, Cambridge CB4 0WZ

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TiGenix is a biomedical company that focuses on innovative local treatments for damaged and osteoarthritic joints. Based in Leuven, Belgium, TiGenix was founded in 2000 by Professor Frank P. Luyten, rheumatologist and renowned scientist and Gil Beyen MBA, bioengineer and CEO of the company since its inception. TiGenix is built on technologies developed at the universities of Leuven and Ghent. The company’s scientific background and expertise has concentrated on the developmental biology of cartilage, bone and other connective tissues. The insights TiGenix’ scientific founders gained into the biology of cartilage have led to the development of a technology platform focused on finding solutions for damaged and diseased cartilage.

TwistDx Ltd www.twistdx.co.uk Tel: 01223 4967000 Minerva Building, Babraham Research Campus, Babraham, Cambridge CB22 3AT

A TwistDx has developed an ultra-rapid DNA/RNA detection technology. Recombinase Polymerase Amplification (RPA) can detect DNA and RNA within 20 minutes using a revolutionary DNA amplification system which operates at low constant temperatures. No complex sample handling is required, and reaction behaviour can be monitored by fluorescence or in equipment-free formats. TwistDx is currently completing development of the first commercial assays, including a point-of-care test for MRSA. Reagents for the research market will be available during 2008.

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UK Trade and Investment (Sector Team) www.uklifescience.co.uk www.uktradeinvest.gov.uk

UK Trade & Investment (UKTI) is the Government organisation that helps UK-based companies succeed in an increasingly global economy. UKTI services are tailored to the needs of individual businesses to maximise their international success. We provide companies with knowledge, advice and practical support. UKTI also helps overseas companies bring high quality investment to the UK’s vibrant economy - acknowledged as Europe’s best place from which to succeed in global business. We provide support and advice to investors at all stages of their business decision-making. UKTI offers expertise and contacts through a network of international specialists throughout the UK, and in British Embassies and other diplomatic offices around the world. We work closely with colleagues in the Department for Business, and the Department for Health. UKTI deploys industry specialists to support the marketing of the UK Life Sciences and to identify commercial opportunities in overseas markets. Specialists are also tasked with increasing the level of international Life Science R&D investment in the UK, promoting the benefits of R&D in the UK to a targeted group of overseas owned companies.

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For further details see: www.uktradeinvest.gov.uk www.uklifescience.co.uk

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Vernalis Clive Evans admin@vernalis.com www.vernalis.com Tel: 01223 895555 Granta Park, Abington, Cambridge, Cambridgeshire CB21 6GB

Vernalis is a development stage pharmaceutical company with significant expertise in taking promising product candidates along a commercially-focused path to market. The Group has one marketed product, frovatriptan for the acute treatment of migraine, and eleven candidates in development, eight of which are designated priority programmes. Five of these priority programmes are currently unpartnered and three are partnered. Pipeline programmes are derived from both our own research activities where we have significant expertise in fragment and structure based drug discovery, as well as from collaborations. Our technologies, capabilities and products are endorsed by collaborations with Biogen Idec, Chiesi, Endo, GSK, Menarini, Novartis and Servier.

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Xention Limited Tim Brears tim.brears@xention.com www.xention.com Tel: 01223 493900 Iconix Park, London Road, Pampisford, Cambridge CB22 3EG

Xention is a biopharmaceutical company specialising in the discovery and development of ion channel-modulating drugs. The company’s proprietary discovery approach allows the company to design and optimise potent and selective small-molecule drugs that modulate ion channel targets. The Company is developing a portfolio of products that will address current limitations in the treatment of atrial fibrillation. It is currently focussing on the development of modulators of two novel, but well characterised, ion channels and expects to develop breakthrough products in this area of huge unmet medical need.

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Xiangcam TCM Research Centre Tel: 01223 497111

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Meditrina Building, Babraham, Cambridge CB22 3AT

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XiangCam, being established in Cambridge in November 2007 by Guangzhou Xiangxue Pharmaceutical Company Ltd. (Xiangxue) which is based in south of China, is interesting in promoting modernization and globalisation of Traditional Chinese Medicine (TCM) with international collaborative research. XiangCam is the first TCM research organisation in the UK invested by Chinese pharmaceuticals. In pursuit of innovative TCM discovery, XiangCam joints theoretical and practical experiences of TCM in China with high techniques and advanced research facilities in the UK. XiangCam has built close relationship with several prestigious universities or institutes both in the UK and China, and has started the mutual benefit research projects already. Our main strategies are: Investigating the mechanisms of TCM function; Developing the new generation Chinese Medicine and natural health care products; Being the platform for UK-China collaboration on TCM research. Our research projects are: Further development of the existing product on anti-flu and the perfection of its quality control method; Investigation of selected herbs and their active ingredients, evaluating their potential to become new drugs; Investigation quality control methods and standards of TCM.

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Zoragen Biotechnologies Dr. Igor Kojic igor.kojic@zoragenbiotech.com www.loxbridgeresearch.com Tel: 07827 237727 One Riverside, Granta Park, Great Abington, Cambridge, Cambrigeshire CB21 6AD

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Zoragen Biotechnologies LLP Inc. is a diagnostic research company dedicated to the discovery, development and commercialization of novel techniques to make prenatal testing safer. Zoragen is a dynamic company that undertakes proof-of-concept research work, specialising in the creation of innovative IP in the area of non-Invasive prenatal diagnostics (NIPD) for global commercialisation. Recently, Zoragen had ethical approval for clinical diagnostic trials with Oxford University providing samples and clinical support granted provisionally in 2008. Shortly after, Zoragen commenced clinical diagnostic R&D with receipt of first samples in mid-2008. To-date, an IPRprotected proof-of-concept is still being developed.

One Nucleus Silver Members

001 Limited Chris Smith

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chris.smith@001ltd.co.uk www.001ltd.co.uk Tel: 0845 389 2001 3 Prime Point, Bessemer Road, Welwyn Garden City, Hertfordshire AL7 1HB

42 Technology Ltd

www.42technology.com

Fax: 01480 32701

Our business model and driving ethic is that we WORK FOR YOU and not the energy supply companies. This is demonstrated by the fact that the majority of our fees are derived from a percentage of the actual savings achieved and not from beneficial sales commissions. Based in Welwyn Garden City, Hertfordshire and founded in 2001, we have successfully grown year on year and now manage energy portfolios for businesses across all sectors and geographical regions, which includes some of the UKâ&#x20AC;&#x2122;s best known brands.

Tel: 01480 302700

Meadow Lane, St Ives PE27 4LG

42 Technology designs and develops innovative products and processes for medical device, biotech and drug delivery applications. We have a strong team of industry experienced engineers, complemented by a network of associates which allows us to provide teams matched to individual projects and client needs. The services we offer range from technology road mapping and concept generation through to design for manufacture and process optimisation. We have extensive experience of product and instrumentation design for medical device, pharmaceutical and biotech companies. We also provide quality and regulatory support for:- Regulatory road mapping and planning- FDA submissions and CE marking- ISO 13485 and cGMP quality system implementation, training and audit- Risk analysis and management â&#x20AC;&#x201C; planning and implementation- Process and computer system validation to FDA standards- Supplier mentoring and quality improvement programs

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Abcellute Tissue Bank

www.abcellutetissuebank.org

BioPark, Broadwater Road, Welwyn Garden City AL7 3AX

The biomedical researchers source of ethically approved, donor consented human tissue. The tissue bank can provide you with the human tissue you need in order to conduct your research. Abcellute Tissue Bank has received UK NHS Research Ethics Committee approval as a Research Tissue Bank to procure, process and dispatch a wide range of human tissues, organs and cells to researchers in industry, academia and healthcare institutions across the world. The Abcellute Tissue Bank is a not for profit, cost recovery company formed in October 2009 to supply tissues and cells to support biomedical research

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Abingworth LLP John Shields

shields@abingworth.com

Tel: 020 7534 1500

www.abingworth.com

38 Jermyn St, London SW1Y 6DN United Kingdom

Abingworth is an international investment group dedicated exclusively to the life sciences and healthcare sectors. We invest across all stages of company development including early and late-stage venture financing, growth equity and public companies. Founded in 1973, Abingworth has a lengthy track record of building market leading companies. Our specialist team of over 20 professionals has a broad range of skills, including scientific and business expertise as well as investment banking, recruitment and legal knowledge. These resources are made available to portfolio companies. Abingworth has funds under management of over $1.25 billion and offices in London, Menlo Park (California) and Boston.

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ABS Laboratories Ltd Dr Mira V. Doig

mira.abs@biopark.org.uk www.abslabs.com

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Tel: 01767 358669 ABS Laboratories, BioPark, Broadwater Road, Welwyn Garden City, Hertfordshire AL7 3AX

One Nucleus Directory 2011

ABS Laboratories is a MHRA GLP and GCP accredited CRO who specialise quantifying drugs, metabolites and biomarkers in biological fluids. We are expert at developing, validating and applying sophisticated techniques to quantify drugs and metabolites in biological fluids using LC-MS/MS, GC and GC-MS. We also quantify a vast range of biomarkers using multiplexed assays on the MSD platform. Our skills, experience and state of the art equipment means that we can support a variety of companies: Small, medium and large Pharmaceutical R&D programmes with their pharmacokinetic and biomarker assays; the NHS for specialist assay requirements supporting clinical diagnosis, screening and therapeutic drug monitoring and University and charitable organisations research programmes.

Acacia Pharma Andrew Muncey andrewmuncey @acaciapharma.com www.acaciapharma.com Tel: 01223 875130

A Acacia Pharma is a pharmaceutical company focused on cancer supportive care - the management of the symptoms cancer, or the management of the side-effects of the treatments of cancer. Acacia Pharma discovers and develops cancer supportive care product opportunities based on established drugs which therefore have a high probability of success. This approach allows Acacia to capitalise on publicly available information, thereby lowering development risk, time and cost compared to new chemical or molecular entities, whilst delivering products of high value in areas of unmet need.

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Harston Mill, Harston, Cambridge CB22 7GG United Kingdom

Accentbio

contact@accentbio.com www.accentbio.com St John’s Innovation Centre, Cowley Road, Cambridge CB4 0WS

We are currently working in areas of Women’s Health, Oncology, Carbon Capture, and Rubber Recycling. We start up and nurture new businesses, perform technology audits for investors, raise funds, and assist with project planning and management of projects. We work in partnership with the originating scientists and share any revenue generated through the commercialisation of technology from the collaboration.

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ACM Global Central Laboratory Theresa Thackray tthackray@acmgloballab.co.uk www.acmgloballab.com Tel: 01904 699432

ACM Global Central Laboratory is a global force in central laboratory testing. It’s our flexible approach, attention to detail and customer service that sets us apart from the competition. With a staff of 400 laboratory experts, ACM Global is able to offer a broad and customised menu of safety and specialty tests for clinical trials. Our analytical team performs 13 million tests each year, featuring more than 1,500 individual tests spanning all medical disciplines. ACM Global has extensive experience conducting clinical trials across the globe with operations that extend to 60 countries, including the Americas, Europe, Australia, India and China.

Aviator Court, Clifton Moorgate, York YO30 4UZ

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Activiomics Mark Warne

Activiomics is a privately owned spin-out company from Barts Cancer Institute at Queen Mary, University of London.

info@activiomics.com

It has developed innovative technologies that utilise mass spectrometry to interrogate and interpret the activity of cellular signalling pathways, generating high value information for the pharmaceutical and biotechnology industry.

Its novel TIQUAS platform enables the label free quantification of phosphopeptides for biomarker discovery and drug profiling. Unlike other phosphoproteomics techniques, TIQUAS can comprehensively profile and crosscompare phosphopeptides, ensuring accurate and reproducible data.

www.activiomics.com Tel: 0845 5195 091 Fax: 0845 5195 092 24 Cornhill, London EC3V 3ND

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Adelphi Healthcare Packaging John Hockley John.hockley@adelphi-hp.com www.adelphi-hp.com Tel: 01483 760950 Mob: 07787 134140 Adelphi Healthcare Packaging, Olympus House, Mill Green Road, Haywards Heath, West Sussex RH16 1XQ

Adelphi Healthcare Packaging specialises in the supply of primary packaging to both the pharmaceutical and biotechnology industries and holds a comprehensive range of glass, plastic and aluminium containers, precision dispensing systems and various closures including stoppers, crimp seals and screw caps. Adelphi stocks a number of specialist vials and stoppers that are particularly suited to new product development and that provide a highly inert product contact surface. Our particular speciality is helping companies in the very early stages of development to ensure that primary packaging choices are the most appropriate, both commercially and technically for their products.

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www.onenucleus.com

Advanced Microbial Diagnostics Ltd Fax: 01234 824667

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Colworth Science Park, Sharnbrook MK44 1LQ

Advanced Microbial Diagnostics Ltd., was formed in 2006 as a separate entity from other business activities in order to pursue major innovations in clinical microbiological test systems. This was part of a diversification into several operations after some 25 years within Unilever’s Diagnostic business, with experience of R&D involving products such as Sensititre, Rapid Sensititre , Clearview Strep A, Clearview Chlamydia and others, plus generation of substantial diagnostics IP. Advanced Microbial Diagnostics has a very focussed interest in Antibiotic Susceptibility Testing , especially Rapid Methods and dealing with Antibiotic Resistance mechanisms within such tests . The company has some very advanced technologies in photonics, microfluidics and of course microbiology along with various ‘in house’ innovations at various stages. All of these are being integrated in order to implement a very novel product concept.

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Air Liquide UK Ltd

www.uk.airliquide.com

Fax: 01675 467022

Tel: 01675 462424

Station Road, Coleshill, Birmingham B46 1JY

Air Liquide UK have extensive experience in the Biotechnology and Laboratory and Analysis field, offering a wide range of products and services to help you increase yield, improve product quality and reduce production hazards. We are constantly looking at ways we can help our customers improve quality, safety and costs. We work closely with our customers to ensure they can concentrate and focus on their core business, leaving their production and laboratory gases, dry ice and equipment requirements to Air Liquide UK.

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Alacrita Robert Johnson

Alacrita provides expertise-based consulting services to the pharmaceutical, biotechnology and life science sectors.

rjohnson@alacritaconsulting.com

We combine extensive industry experience and broad functional capabilities to help our clients create sustainable value, providing:

www.alacritaconsulting.com Tel: 07884 183 560 The London Bioscience Centre, 2 Royal College Street, London NW1 0NH

• flexible managerial support, ranging from a single individual on a part time basis through to an entire management team. • multidisciplinary project teams to conduct specific assignments; • instant expertise: high-level strategic, commercial and technical; Alacrita’s team has industry experience and a consulting track record, ensuring that projects are delivered with both professionalism and real-world relevance.

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Albany Regulatory Consulting Limited www.albanyconsulting.co.uk 91 Impington Lane, Impington, Cambridge CB24 9NJ

Providing services to US, Australian, Canadian and European companies for: Regulatory strategy (Oncology, cardiovascular, anti-infectives, renal, orthopaedics, biotechnology, biosimilars and Orphan Drugs) Early strategic development advice to biotechnology start-ups Clinical Trial Applications (CTAs) (USA, EU, Switzerland) Orphan Drug Applications Scientific Advice and protocol assistance National Scientific Advice meetings Marketing Authorisation Applications (MAAs Due Diligence).

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Allmi-Care Ltd www.quool.co.uk

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BioCity, Pennyfoot Street, Nottingham NG1 1GF

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Development of innovative hydrogel topical patch formulations.

Almac Sciences www.almacgroup.com Tel: 028 383 32200 Fax: 028 3833 2200 20 Seagoe Industrial Estate, Craigavon, Northern Ireland BT63 5QD

A Almac is a financially stable, privately owned organisation with over 30 years experience. The Group provides integrated development solutions to over 600 customers worldwide including all the world leaders in the pharmaceutical and biotechnology sectors. Almac provides a seamless, fast and efficient route from drug discovery through to market. Our range of services includes: Research: Almac provides genomics based solutions, informing drug discovery and enabling personalised medicine. Chemical & Pharmaceutical Development: Almac accelerates the development of customers’ drug candidates through the effective integration of science and manufacturing to provide drug substance & product. Clinical Development: Almac is unique in the industry, offering fully integrated world class clinical trial supplies & IVR/IWR technology. Commercial: Almac provides solid dosage form commercial manufacture and packaging for EU & US markets. Commercial support services facilitate EU market access for non-EU product.

michelle.peake@alphabiologics.com www.alphabiologics.com Tel: 01223 496070

Alpha Biologics manufacture monoclonal antibodies and recombinant proteins from two sites: Cambridge UK: Research and process development laboratories that work on bacteria, yeast or mammalian cell lines. Activities include cell line selection, cell banking, process development in bioreactors or wave bags, product yield optimisation and downstream separation. Optimised processes are transferred for manufacture in Alpha’s own cGMP production facility, or to other plants specified by our clients. Penang, Malaysia: a major new cGMP mammalian cell protein manufacturing plant designed to be FDA / EMEA compliant, with bioreactors ranging from 10 to 500 litres, and advanced perfusion capability for higher product yields.

Alpha Biologics, Babraham Research Campus, Babraham, Cambridge CB22 3AT

robs@amphora-research.com www.amphora-research.com Tel: 0845 230 0160 PO Box 3940, Bracknell, Berkshire RG42 2XN

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Amphora Research Systems Rob Swan

Alpha Biologics Michelle Peake, Chief Operating Officer

Amphora is one of the world’s leading suppliers of replacements for the Bound Laboratory Notebook. Our solutions are in use around the world by companies large and small, helping scientists work better, collaborate easily with each other, and protect their inventions. At Amphora we focus on replacing the bound paper notebook with a searchable, shareable and secure electronic version. In the process we make sure that you don’t compromise your patent protection, in fact our customers and their lawyers report that they end up with much better IP records.

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AMS Biotechnology (Europe) Limited www.amsbio.com 184 Milton Park, Abingdon OX14 4SE

Founded in 1987, amsbio is recognised as a leading international source of unique & innovative products & custom services for life sciences research. The amsbio range includes over 68,000 polyclonal & monoclonal antibodies, peptides, recombinant proteins, extracellular matrix, molecular detection reagents, & tissue DNA, RNA, protein & microarray products. Key research areas include: apoptosis, cell invasion & migration, cell signaling, DNA damage, electrophoresis, glycobiology, posttranslational modification & stem cell biology.

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The Ann Hayes Consultancy Ltd annghayes@yahoo.co.uk Tel: 01763 281375

Ann operates as an independent consultant, working with biotech and pharma companies and investors, to help with drug discovery programmes, particularly in the areas of CNS diseases and pain. She specializes in helping with long-term discovery strategy, portfolio management and drug discovery project management. She has also helped cofound several small companies and has sat on various boards, helping particularly to develop corporate strategy. She also sits on various advisory boards, helping particularly with scientific strategy.

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www.onenucleus.com

Antitope Ltd www.antitope.com

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Tel: 01223 496190 Fax: 01223 496191

Antitope was formed in Cambridge, UK in 2004 in order to advance previous research of the founders by developing proprietary technologies for immunogenicity prediction, antibody humanization and engineering protein therapeutics. To date, we have entered into over 50 different agreements with pharmaceutical and biotechnology companies worldwide to apply our technologies for the development of improved biologics.

Babraham Research Campus, Babraham, Cambridge CB22 3AT

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Applied Medical Technology Ltd

support@applied-medical.co.uk

Tel: 01223 420415

www.applied-medical.co.uk

4 Orwell Furlong, Cowley Road, Cambridge CB4 0WY

Applied Medical Technologies Ltd based in Cambridge, is the UKs leading supplier of ambulatory systems for the continuous administration of drugs for a variety of clinical purposes. We also offer the most comprehensive range of high quality subcutaneous infusion administration sets. We develop bespoke solutions for therapies that benefit from a non-intravenous route of drug delivery by providing the most reliable, comfortable and convenient disposable systems available. Therapies which benefit from our technologies include: • Oncology • Pain relief • Primary Immunodeficiency • Intrathecal Infusion • Thallasemia • Hormone Therapy

• Pulmonary Hypertension • Asthma • Rehydration

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Aqix Limited

www.aqix.com

Imperial College BioIncubator, London, Exhibition Road SW7 2AZ

Aqix Limited manufacture the product to GMP for use as a blood expander, transplant solution and transporting human tissue samples. It also is in development for use in regenerative medicine. Aqix RS-I is a GMP, synthetic interstitial fluid designed from first principles to promote homoeostasis and membrane activity.

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Arco Limited burystedmunds.branch @arco.co.uk www.arco.co.uk Tel: 01284 702533 Fax: 01284 750529 Arco House, Easlea Road, Moreton Hall Industrial Estate, Bury St Edmunds IP32 7BY

Arecor Limited Sheridan Cook

info@arecor.com www.arecor.com

Tel: 01223 426060

2 Cambridge Science Park, Cambridge CB4 0FE

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Arco is the UK’s leading supplier of personal protective equipment, workwear and workplace safety products. As such it is widely recognised as a provider of expert advice, services and safety solutions for businesses in every market sector. Founded in 1884, the Hull-based, 4th generation family business now has over 110,000 customers. Through its team of product specialists, its product catalogue and a rapidly expanding 40-strong branch network, Arco offers a world-class range of quality assured, branded and own-brand products, carefully selected from ethically compliant suppliers. Products include personal protective equipment, clothing including front and backof-house career wear, footwear, gloves, workplace safety and hygiene products. Arco is dedicated to its Corporate Social Responsibility policy and continually demonstrates its support of local business communities and charitable organisations. In 2005, Arco became a member of the BITC Percent Club by donating 1% of pre-tax profits to charities. In 2007, Arco became a member of the Ethical Trading Initiative (ETI).

One Nucleus Directory 2011

Arecor Limited was established to provide formulation solutions to pharmaceutical and biotech companies developing drugs, vaccines, medical devices and diagnostics. Proteins and vaccines are often fragile entities, and stability can represent significant constraints in the development of new products and extending the use of existing products. Arecor has developed Arestat™, a patented set of tools for stabilization, to enable the presentation of labile biologicals as stable aqueous formulations even at high concentrations or in situations where cold storage is not practical or desirable.

Argo Consulting Ltd Stephen Lang stephenm.lang@btinternet.com Tel: 01799 513209 Oak Cottage, Catmere End, Saffron, Walden, Essex CB11 4XG

A Argo Consulting specialises in providing the full range of Business Development services to the Medtech industry, namely: identification of optimal development strategies, identifying and acquiring suitable companies or technology, selling or licensing technology to larger companies. I will work with you to identify the right strategic option, identify and work with partners, conduct valuations, manage diligence investigations, negotiate and draft agreements and assist with implementation of the deal. I bring over 20 years of expertise and experiences from many deals to bear on each Business Development project. I also present training courses in the art and science of negotiation.

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Arrow Therapeutics Ltd

www.arrowt.co.uk

Britannia House, 7 Trinity Street, London SE1 1DB

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Aseptika Ltd Jessica Auton jessica.auton@aseptika.com www.aseptika.com Tel: 01480 352821 14 Elizabeth Drive, Hartford, Huntingdon, Cambridgeshire PE29 1WA

Aseptika Ltd operates to support Life Science SME’s, the public sector, and academia to obtain public grant funding, connect with technology partners and commercialise innovative products.

We have expertise in business modelling, securing funding raised from grants, corporate partnerships, product development and commercialisation of basic research locked up in the public sector, academia or SME’s in the Life Sciences sector. Aseptika’s value-added approach to commercialisation of products is underpinned with expertise in the areas of Grant Proposal writing, Product ideation, Business modelling, Market insight, Product development, Project management and Manufacturing.

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ATPBio Ltd

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Avlar BioVentures Ltd info@avlar.com

Venture capital, start-up, funding, biotechnology, healthcare.

www.avlar.com Tel: 01954 211515 Fax: 01954 211516

Highfield Court, Church Lane, Madingley CB23 8AG

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Balanced Clinical Research Services Ltd www.balancedclinical.com

Tel: 01480 382132

10 Pavilion Close, Godmanchester PE29 2WQ

Considering the individual needs of all the stakeholders across the research process, from Sponsors to patients, Balanced Clinical Research has the expertise to develop products for market. These services include consultancy, project management, monitoring and associated clinical trial services. Drawing upon extensive industry experience and knowledge of research needs and using locally based experts. Balanced Clinical Research ensures the best study designs, locations and services to ensure each projectâ&#x20AC;&#x2122;s success.

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Barlow Lyde & Gilbert LLP Barlow Lyde and Gilbert LLP (BLG) is a full service law firm capable of providing legal advice and resources to entrepreneurs, companies and other organisations in the life sciences sector. Our headquarters are in London and we also have an office located in Oxford. Our life sciences team is led by Richard Pike and Simon Gamblin, both partners in the corporate department. In addition, we are pleased to announce the recent arrival of Michael Stone as a consultant to the team. He brings a wealth of experience in the sector, including 30 years in-house at Glaxo/Glaxo Wellcome. Associate Director Sheila Tormey handles competition and procurement law issues. We have lawyers across the firm experienced in advising those in the life sciences sector on all issues affecting their businesses, from starting out to realising the value of their endeavours.

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Barrett Webb Limited Sue Rossiter sr@barrettwebb.com

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www.barrettwebb.com Tel: 01727 857755 Dagnall House, Lower Dagnall Street, St Albans, Hertfordshire AL3 4PA

At Barrett Webb we provide our clients with a key competitive advantage â&#x20AC;&#x201C; exceptionally talented people who can deliver real value to their organisations. We are a leading UK-based executive search firm specialising exclusively in the life sciences industry. Our clients are major global companies, private equity backed organisations, start-up companies and NGOs across the biotechnology, pharmaceuticals, medical technology, consumer health and healthcare services sectors. Our consultants have deep industry expertise, backed by a multi-lingual research capability. We manage search assignments across all functional areas including R&D, Marketing, Sales, Business Development, Medical, Technical, Regulatory, Quality, Production, and Business Support areas.

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BBSRC Dr Alex Chaix, Senior Innovation Manager

To promote and support, by any means, high-quality basic, strategic and applied research and related postgraduate training relating to the understanding and exploitation of biological systems.

alex.chaix@bbsrc.ac.uk

To advance knowledge and technology (including the promotion and support of the exploitation of research outcomes), and provide trained scientists and engineers, which meet the needs of users and beneficiaries (including the agriculture, bioprocessing, chemical, food, healthcare, pharmaceutical and other biotechnological related industries), thereby contributing to the economic competitiveness of the United Kingdom and the quality of life.

www.bbsrc.ac.uk Tel: 01793 413237 BBSRC, Polaris House, North Star Avenue, Swindon SN2 1UH

Beremans Limited Dr. Nicholas Miller

nm01@beremans.com www.beremans.com

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Tel: 0044 1223969286 0044 1483890581 39 Parkside, Cambridge CB1 1PN United Kingdom

One Nucleus Directory 2011

Beremans provides business intelligence and independent research in the Life Sciences sector to support investment and business decisions. Clients include life sciences, healthcare and pharmaceutical companies, government bodies, fund managers and venture capital organisations. In addition, Beremans provides consulting services to selected pharmaceutical and biotechnology companies. These services typically comprise market research, market assessment, competitor intelligence or business development activities. Beremans has particular expertise in the fields of vaccines and immunotherapy, infection control, oncology, regenerative medicine, medical implants, and drug discovery.

Bio Nano Consulting Ltd www.bio-nano-consulting.com 85 Tottenham Court Road, London W1T 4TQ

We are the first consultancy in Europe to focus on the intersection between bio and nanotechnology, providing product development and strategic consultancy, project management and access to state of the art instrumentation.

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Bioanalytical Systems Ltd (BASi) Emily Chinn

echinn@basinc.com www.basinc.com

Established in 1974, BASi focus on developing innovative services and products that increase efficiency and reduce the costs associated with taking new drugs to market. From our facilities across the US and UK we offer an extensive array of contract laboratory services including: • Bioanalysis • Toxicology • Non-GLP Pre-Clinical Research • Immunoassay Services • Pharmaceutical Analysis and Stability Storage BASi’s UK Bioanalysis facility boasts a modern GLP-compliant facility fully equipped with AB Sciex analytical systems. Our team of highly experienced scientists provide full method development/transfer and validation to support both non-clinical and clinical projects. We have the capacity to analyze samples from small proof-of-concept studies through to late-phase clinical trials. The breadth and depth of our technology and scientific talent ensures that our clients receive the high quality data and fast turnaround they need, every time. A clear focus is placed on quality at all stages, supported by our dedicated, independent Quality Assurance Team. BASi scientific instruments include the Culex family of in vivo sampling systems (whole blood, plasma, microdialysis and ultrafiltration) and electrochemical detectors. For more information please contact Emily Chinn: echinn@basinc.com or visit our website www.basinc.com

mlloydevans@biobridge.co.uk www.biobridge.co.uk Tel: 01223 566850 45 St Barnabas Road, Cambridge CB1 2BX United Kingdom

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BioBridge Limited Mr. Meredith Lloyd-Evans

BioBridge® was founded in 1989 to address challenges to commercialisation for innovations in biosciences. We help our clients through the entire product chain, discovery development to market entry and maintenance, including due diligence for investors. Our achievements are in all bioscience sectors including human and animal health, medical technology and bioengineering, food, agriculture, general biotechnology and industrial biotechnology (green chemistry, biomass use for natural products, bioenergy and bioremediation). Our clients are public organisations, private companies and innovation-generators such as Universities and research bodies. Current and recent work includes monitoring, expert oversight and support for publicly-funded projects in industrial biotechnology; regulatory strategy for a novel pet food additive; global benchmarking survey for an international animal health industry body; product-finding for pharmaceutical companies; network creation in environment and algal technologies; strategic analysis of GM crops and food regulations; integrating low carbon strategies with life sciences; membership of an EU working group on marine biotechnology; & product safety and compliance oversight for a biomaterials company.

Biocair International Ltd Biocair operates a specialist logistics service, which focuses solely on the material produced by the pharmaceutical, biotechnology and medical research communities. We have over 20 years’ experience in this field. Biocair is a global organisation, with main offices in Boston USA, Cambridge UK and Osaka JP. We specialise in giving up to date advice on classification and regulatory requirements of hazardous material which can include infectious, toxic, biological, genetically modified and radioactive. We apply the correct procedures, supply all packaging and documentation and fulfil every legal requirement, while planning the most efficient routes globally, including clinical trial management. Biocair offer full temperature control including dry ice, refrigerated (2 to 8°C), ambient, warm and liquid nitrogen. Our staff, including science graduates and regulatory experts, have received training from accredited dangerous goods schools in the classification, documentation, packaging and labelling of hazardous materials.

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Bioedge Pharma Consultancy Limited mail@bioedge.co.uk www.bioedge.co.uk Tel: 01296 771126 Lower Farm House, Grendon Road, Edgcott, Aylesbury HP18 0TN

Bioedge Pharma is a company offering drug development services to virtual pharmaceutical and biotechnology companies around the world, with particular focus on CMC and Project Management services. Bioedge Pharma works with a wide range of companies at all stages of development from late stage research though to marketed products. The company has an extensive network of international service providers and other consultants and hence can offer assistance in virtually all aspects of drug development. Bioedge Pharma is particularly familiar with assisting small virtual companies make the transition from research to development and can either establish a virtual development team or form part of such a team to take drugs through to first in man studies. Assistance with selection and management of external service providers (CROs and CMOs) is a key aspect of development with which Bioedge Pharma is very experienced.

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BioLauncher Ltd Rowan Gardner

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rowan@biolauncher.com www.biolauncher.com Tel: 01763 837299 Chesterford Research Park, Saffron Walden CB10 1XL

Biolauncher is an expert advisory company that helps growing companies formulate their product, commercial and corporate strategy, prepare for funding and broker relationships. The company also provides technology scouting and evaluation services to companies seeking access to innovation. The company’s services are supported by our proprietary information and analytic system, ShowcaseBio that aggregates commercial life science information from over 350 sources. To find out more about our work with life science companies, investors and public sector bodies visit biolauncher.com

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BioMoti

www.biomoti.com

Innovation Centre, 42 New Road, London E1 2AX

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BioMoti Limited is a privately held UK based company engaged in the development of platform drug delivery technologies. In particular, BioMoti focuses on improving the delivery of active agents to the intracellular space. This is achieved by packaging the drug compounds into functionalised microparticles designed to access the interior of targeted biological cells. BioMoti is currently focussed on improving the delivery of drugs in cancer; helping to increase efficacy and reduce toxicity. Paired with the appropriate pharmaceutical agents, BioMoti technology can form a substantial portion of the worldwide market in the treatment of specific cancers by offering opportunities to target new intracellular mechanisms, reformulate compounds and contribute to the patent extension of marketed drugs. The total oncology market was worth over $66 billion in 2007 and strong doubledigit growth is expected due to increased demand from an ageing population predominantly affected by cancer and the on-going need for innovative medicines.

BioPark

www.biopark.co.uk

Broadwater Road, Welwyn Garden City AL7 3AX

Incubator: just 30 minutes by rail from Central London offering flexible, realistically-priced space for University spinouts and start-ups. Grow-on and Relocation: laboratory and office accommodation in various configurations. Inward Investment: ideally centred within the research ‘golden triangle’, Cambridge-London-Oxford offering prestigious accommodation for bioscience and health technology businesses intending to establish a base in the UK. Excellent location, close to the railway station and motorways - around an hour to Heathrow, Luton and Stansted airports. Professional Service Providers: flexible office accommodation with comprehensive meeting, conference and event facilities including a 66 seat lecture theatre and the larger ‘Pillars Suite’.

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BioPartner.co.uk www.biopartner.co.uk The Magdalen Centre, Oxford Science Park, Oxford OX4 4GA

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BioPharmaLogic LLC info@BioPharmaLogic.com

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www.biopharmalogic.com St John’s Innovation Centre, Cowley Road, Cambridge CB4 0WS

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One Nucleus Directory 2011

Biopartner.co.uk is a UK Government accredited Trade Organisation facilitating international partnering for collaborations with Life Sciences organisations across the UK. BioPartner supports UK SMEs and startups, and signposts organisations worldwide to UK expertise. Biopartner.co.uk organises international biopartnering events, projects and missions, operating both independently and in partnership with the UK government. As an Accredited Trade Organisation it disseminates tradeshow access grants to help UK-based SMEs exhibit their services and products in new overseas markets.

Biopharma Technology Ltd Dora Halmi btl@biopharma.co.uk www.biopharma.co.uk Tel: 01962 841092

BTL has unparalleled track record in freeze drying diverse and complex products including liposome, foodstuffs, vaccines, cells, nucleic acids, proteins, small molecule APIs, bacteria, various biomaterials and new drug formulations for our customers around the world. Using custom-designed analytical instruments and decades of experience, thermal behaviour of products can be characterised scientifically. This enables formulations to be developed rationally and safe and repeatable cycles calculated development, trial and production size batches. We also offer small scale batch processing for all applications.

Biopharma House, Winnall Valley Road, Winchester SO23 0LD United Kingdom

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BioScience Communications

www.bioscicom.net

Southside, 105 Victoria Street, London SW1E 6QT

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Biosynergy (Europe) Ltd info@biosynergyeurope.com www.biosynergyeurope.com Tel: 01223 579345 Fax: 01223 579349 12 Pembroke Avenue, Denny Industrial Centre, Waterbeach, Cambridge CB5 9PB

Contract manufacturer of biologics for immunodiagnostic, bio-pharmaceutical and environmental biotechnology applications. Contract RD; creation, development and optimisation of cell lines; process development and validation; production and purification of proteins (milligram to multi-gram quantities)to enable characterisation, pre-clinical testing, and scale-up for clinical trials. Specialist in hybridoma technology and production/purification of monoclonal antibodies and recombinant proteins from mammalian cell lines. Development of bioassays for environmental monitoring. Microbial and monoclonal antibody-based bioassays for identifying pathogens and determining toxicity of wastewater and groundwater. Technologies: Hollowfibre bioreactors; spinner/roller culture; stirred vessel bioreactors; Affinity, ion-exchange and size exclusion chromatography.

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BioTrans Tel: 01462 457568 Griffin House, 1A Coach Drive, Hitchin SG4 9AP

BioTrans has a wealth of knowledge and experience in progressing drugs from early compound discovery to regulatory submissions and registration. Biotrans provides pre-clinical interim and consultancy services including: Drug metabolism and pre-clinical drug discovery and development including the application of new technology to improve success rates in compound development. Process re-engineering to improve product delivery. Any process can be improved based upon systematic process mapping and analysis but even simple changes can yield marked improvements in productivity (e.g., study design, automation or reporting). Such analysis can also be highly beneficial in designing marketing and business development strategies and materials. Staff training and continued professional development is mandated in many professions and for good reason. However, in many organisations the sourcing and development of training materials can be problematic to resource. BioTrans can use its experience and pre-existing materials to help your organisation development your staff to their full potential.

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Biotrial International Dr. Matthew Konneh matthew.konneh@biotrial.co.uk www.biotrial.com Tel: 0207 060 9110 Biotrial International, Temple Chambers, 3-7 Temple Avenue, London EC4Y 0HP

Biotrial is a full-service partner, providing state of the art services in all key areas of the drug development, including: Phase I, Phase II-IV, Central Labs., Oncology, Biometrics and Preclinical Safety and Efficacy Pharmacology. Biotrial is a leading service provider in early development in Europe. Biotrial GLP non-clinical services include: safety pharmacology in vivo studies (core battery, supplemental and follow up studies), therapeutic efficacy and tailor made models. Biotrial has also established a strong group for oncology services with links to anticancer institutes and oncology departments throughout Europe, performing trials from early development up to Phase III. Biotrial is a pan European early development CRO with facilities and offices in France (Rennes & Paris), Belgium (Brussels) and UK (London).

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www.onenucleus.com

BOC www.boconline.co.uk

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The Priestley Centre, Surrey Research Park, Guildford GU2 7XY

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Boult Wade Tennant

Matthew Spencer, Partner

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mspencer@boult.com www.boult.com Tel: 0207 430 7500 CPC4 Capital Park, Cambridge Road, Cambridge CB21 5XE

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Andrew Glover

www.bridgepartners.co.uk Tel: 01223 750150 St John’s Innovation Centre, Cowley Road, Cambridge CB4 0WS

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Timothy Fitzgerald

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Tel: 01664 503700

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www.bridgehead.com

Bridgehead International Ltd, Pera Innovation Park, Nottingham Road, Melton Mowbray, Leicestershire LE13 0PB

Tel: 01234 266300 Fax: 01234 266488

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4 Shuttleworth Road, Elms Industrial Estate, Bedford MK41 0EP

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Bridge Partners specialise in helping small to medium-sized organisations to get the best from their information and communications technology. If you are starting from scratch, we can advise you on what to buy to support your business objectives. Where you have already made an investment in ICT, we will show you how to use it for maximum business benefit and support your systems on an ongoing basis. We also provide dedicated internet connections, specialising in provision to Business Parks and multi-tenanted buildings. We also provide hosting. This covers email, backup, disaster recovery solutions, servers as well as website and applications.

Bridgehead International is a leading biopharmaceutical consultancy group, offering a range of services designed to assist clients in achieving extraordinary growth across the product and technology value chain. Our mission is to work with commercial organisations, government agencies and the investment community to ensure that: • Life science organisations have the funding, structure and strategic focus to deliver high levels of innovation and financial return • Patients have rapid and broad access to new innovative medicines, medical devices and diagnostic tools, particularly in areas of high unmet need. For further information on our services and capabilities please refer to www.bridgehead.com

Briton EMS Ltd www.britonems.co.uk

Bridge Partners are an information and communications technology (ICT) support services company based in Cambridge.

Bridgehead International info@bridgehead.com

Our Life Science attorneys have expertise in a range of areas of biotechnology and biological chemistry including molecular biology, genomics, bioinformatics, diagnostics, array technology, human genetics, stem cells, pharmaceuticals, biosensors, drug delivery systems, research tool inventions, DNA sequencing techniques, lab-inchip technology, vaccines, and herbal medicines.

Bridge Partners info@bridgepartners.co.uk

Boult Wade Tennant is a leading UK and European firm of patent and trade mark attorneys advising on all aspects of intellectual property protection, management and enforcement worldwide. Services include patent drafting, filing and prosecution, EPO oppositions, freedom to operate searches, IP due diligence and infringement opinions.

One Nucleus Directory 2011

Briton EMS offers an Electronics Manufacturing Service. With long experience in the controls, sensors and instrumentation sectors, our assembly facility is geared to manufacturing small to medium runs of high reliability electronic systems. The markets we operate in are wide and varied E.g. Gas detection systems, condition monitoring, test instrumentation, control systems and broadcast electronics Our speciality is for complete product or subsystem build: PCBs, final assembly & test. We support prototype PCB and trial batch assembly through development stages. Our Engineering team will work with you or your third party designers throughout the production engineering stages of your development.

BSG Team Ventures

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BTG International Ltd

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Business Insights Dr. Raheel Shaban rshaban@business-insights.com www.business-insights.com Tel: 020 7551 9571 Business Insights, 119 Farringdon Road, London EC1R 3DA

Business Insights provides you with a clear understanding of the key trends, innovations, and emerging technologies within the life sciences space, to assist with your strategic and tactical planning and business decisions. Our Life Sciences portfolio of reports cover specific sectors such as healthcare markets and therapies, drug discovery, diagnostics, medical devices, wider issues like pharmaceutical outsourcing and strategy, and niche sectors such as drug delivery. These reports are designed to help you make well informed and timely business decisions, and can be used across a wide range of business functions to assess market conditions and devise future strategies.

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Business Relations Department www.business.bbk.ac.uk

Research-intensive higher education institution, member college of the University of London.

Malet Street, Bloomsbury, London WC1E 7HX

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Cambridge Biofreeze Ltd www.cambridgebiofreeze.co.uk Unit 12 Carlton Place, Shire Hill Industrial Estate, Saffron Walden CB11 3AQ

Cambridge Biofreeze Ltd provides 2 services. A BIOREPOSITORY; Safely storing your mission critical samples offsite in our secure facility across the temperature range; -196, -80, -40, -20 and +4 째C. This helps both free up space in your facility allowing for further research and greatly enhances business/research continuity management. Whether they are backup/mirror/archived samples or ones needed on a more regular basis, we can store 1 to a million samples and offer daily collections and retrievals. Our DISASTER RECOVERY SERVICE covers the samples you choose keep in your facility. It guarantees that in the event you have a power failure, freezer mechanical breakdown or flood in your facility, we would be onsite within 4 hours (on a 24/7/365 basis) with the necessary manpower and packing material to return your precious samples to the safety of our facility, where they will remain until the situation has been remedied.

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Cambridge BioScience Limited Mike Kerins

support@bioscience.co.uk www.bioscience.co.uk

Tel: 01223 316855

Cambridge Bioscience is a leading distributor of life science products with a passion for bringing new and exciting technologies to researchers. Working with over forty specialist suppliers around the world, we offer an innovative, extensive and diverse range of over 160,000 products supporting research in the following areas: Cancer, Cell Signalling, Endocrinology, Epigenetics, Inflammation, Innate and Adaptive Immunity, Metabolism, Neuroscience and more.

Fax: 01954 781 323 Cambridge Bioscience, Munro House, Trafalgar Way, Bar Hill, Cambridge CB23 8SQ

Cambridge Cognition Ltd

info@camcog.com

Tel: 01223 810 700

Tunbridge Court, Tunbridge Lane, Bottisham, Cambridge CB25 9TU

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www.cantab.com

Fax: 01223 810 701

Cambridge Cognition Ltd (CCL) develops and markets computerised cognitive testing software under the CANTAB™ brand name. CCL provides software to Academic Research institutions around the world and is the market leader in this sector. CCL is also a leading provider of specialist Cognitive testing products and services to the world-wide pharmaceutical industry, with experience in all phases of drug development in global studies and counts many of the world’s top 15 pharmaceutical companies as clients. CCL has offices in Bottisham outside Cambridge and Cambridge Mass.

Cambridge Design Partnership LLP www.cambridge-design.co.uk

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Cambridge Design Partnership works with both industry leaders and early stage companies to develop their innovative products for the healthcare market. In addition to core skills in product design and user testing, our multidisciplinary team provides expertise in electro- and biomechanics, microengineering, optics, digital imaging, ergonomics, physiology and biochemistry. We support clients from first concepts through to manufacture, user trials, regulatory approval and market testing. We specialise in: diagnostics, drug delivery, minimally-invasive surgery, imaging, wellbeing and exercise science and we are working on projects funded through Department of Health and East of England Strategic Health Authority innovation initiatives. We operate focus groups with health professionals at all levels from NHS Trusts across the country, to gain in depth understanding for each product. This has been pivotal to our clients’ success. Bring us your challenging projects. To see how we have developed products for our other clients, see www.cambridge-design.co.uk.

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Cambridge Enterprise University of Cambridge Shirley Jamieson, Head of Marketing Shirley.Jamieson @enterprise.cam.ac.uk www.enterprise.cam.ac.uk Tel: 01223 760339 Cambridge Enterprise, University of Cambridge, Hauser Forum, 3 Charles Babbage Road, Cambridge CB3 0GT

www.chandb.com Tel: 01799 530009

Fax: 0870 751 7505

Chesterford Research Park, Little Chesterford CB10 1XL

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Cambridge Enterprise provides access to angel and early stage capital through the Cambridge Enterprise Seed Funds and Cambridge Enterprise Venture Partners, and offers business planning, mentoring and other related programmes.

Cambridge Healthcare and Biotech Ltd info@chandb.com

Cambridge Enterprise is responsible for the commercialisation of University of Cambridge intellectual property and is a wholly owned subsidiary of the University. Activities include management and licensing of intellectual property and patents, proof of concept funding and support for University staff and research groups wishing to provide expert advice or facilities to public and private sector organisations.

One Nucleus Directory 2011

Cambridge Healthcare & Biotech is a knowledge-based consultancy serving all sectors of the healthcare industry across the globe. Its team of over 50 Consultants and Associates has steered major products through all aspects of research, development and commercialization. The company brings a unique perspective to solving client problems through in-depth understanding of technology, product development, marketing, healthcare systems and corporate finance embedded in its project teams. In particular, the track record of its team in due diligence is second to none, enabling its clients to maximize value and minimize risk in mergers, acquisitions, divestments and licensing transactions. Services delivered through our Consultants Associates: Business Strategy Licensing Strategy Marketing Strategy RD Strategy Due Diligence Support Mergers, Acquisitions Divestments Valuations Commercial Assessment Distribution Strategy Litigation Support Services delivered in combination with our alliance partners: Regulatory affairs Pricing reimbursement Medical device technology Medical Education Executive search In addition to our ‘normal’ consultancy projects, our fully searchable, unique proprietary database has proven to be of great value to our clients. The database includes: - Profiles of over 7,000 companies with links to external databases such as Pharmaprojects - Contact details for 30,000 people, with brief biographies for over 22,000 of them plus their links to social networking sites such as Linkedin and Twitter - Portfolios for over 450 investors cross linked to over 5,000 specific investments.

Cambridge Medical Innovations Limited info@cam-medical.com www.cam-medical.com Tel: 01223 225333 Fax: 01223 225322 181 Cambridge Science Park, Milton Road, Cambridge CB4 0GJ

Cambridge Medical Innovations Limited (CMI, part of Inverness Medical Innovations Inc) is a dynamic R&D organisation specialising in the development of medical diagnostic devices. CMI is dedicated to developing a series of devices that will help in the diagnosis of diseases and enable more efficient monitoring of human health. Our mission is to develop the diagnostics devices to be sold worldwide. The company is located at the Cambridge Science Park, Cambridge, UK. We have access to a number of biosensor platforms; our core technology is based on robust label-free sensing exploiting high frequency acoustics to specifically diagnose diseases. The systems can directly detect a range of molecules, bacteria and viruses in both crude samples and complex matrices with minimal need for sample processing or purification. This is achieved by attaching a specific target receptor to the surface of an acoustic resonator, using one of a variety of coupling chemistries, followed by delivery of a sample via a micro fluidic flow-based system. The resonant acoustic signal indicates not only the presence of target molecules but also their concentration in the sample.

Karen James

Cambreg has been providing regulatory solutions to pharmaceutical and biotech companies for more than 11 years.

karenjames@cambreg.co.uk

Offering a complete portfolio of regulatory services (advice, dossier preparation, regulatory procedure management and ad hoc support); Cambreg has satisfied over 200 clients worldwide, including those from emerging markets.

Tel: 01480 465755 2 Cabot House, Compass Point Business Park, St. Ives, Cambridgeshire PE27 5JL United Kingdom

The multicultural, highly experienced team helps clients at any stage in the lifecycle of their product from R&D, through registration, to the market and beyond.

Tel: 01223 559393 c/o Bidwells, Trumpington Road, Cambridge CB2 9LD

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Continuing to stay ahead of the game, Cambreg offers clients a commercially focused service.

Co-Director Dr Mike James, an ex-health authority regulator with more than 20 years experience in the industry, specializes in the field of biotechnology.

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Cambridge Science Park www.cambridgesciencepark.co.uk

Cambridge Regulatory Services Ltd

www.cambreg.co.uk

Established by Trinity College in 1970, Cambridge Science Park is the UK’s oldest and most prestigious science park. Now home to over 100 companies and 1,650,000 sq ft of buildings, Cambridge Science Park continues to attract new businesses, from small start-ups and spin-outs to subsidiaries of multinational corporations. For further information please visit www.cambridgesciencepark.co.uk

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CambridgeSoft Corporation info@eu.cambridgesoft.com www.cambridgesoft.com Tel: 01223 464900 Fax: 01223 464990 1 Signet Court, Swann’s Road, Cambridge CB5 8LA

CambridgeSoft is a market leader in software solutions and services for the chemical, biotechnology and pharmaceutical industries. CambridgeSoft has earned an enviable reputation as a supplier of Enterprise informatics solutions across a very broad range of scientific disciplines, including providing Electronic Laboratory Notebook systems to four of the world’s top five Pharmaceutical companies. CambridgeSoft provides: Enterprise solutions, desktop software, scientific databases, and professional services for biotechnology, drug discovery and chemical research, including software, databases, and web sites which enable customers to create, analyze and communicate chemical, biological, and scientific information more effectively. CambridgeSoft’s products are used primarily in the pharmaceutical, biotechnology and chemical industries, as well as in higher education and in academic and government research. The company’s principal software offering, Chem&BioOffice is the de facto standard and primary communication tool on the chemist’s desktop. Chem&BioOffice Enterprise enables research information organizations to manage and share life science information enterprise-wide.

Campbell Charles Associates (2000) Ltd Trials Without The Tribulations:

i.digiovanna@cca2000.co.uk

Campbell Charles Associates has a reputation for quality, timeliness and cost-effectiveness. We aim to provide sponsors with the commitment they would expect from their own clinical research team. We provide a full service CRO or perform individual tasks. CCA has a loyal client base and a high rate of return business. We are a member of PSN - an international network of highly qualified, owner-driven CROs, delivering high quality clinical research services on a multinational scale (www.psnglobal.org).

Tel: 01932 869933 Campbell Charles Associates (2000) Ltd, 48 Station Road, Stoke D’Abernon, Cobham, Surrey KT11 3BN

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Dr Ignazio Di Giovanna

www.cca2000.co.uk

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www.onenucleus.com

Canadian High Commission Caroline Martin

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www.dfait-maeci.gc.ca/london Tel: 0207 258 6600 Fax: 0207 258 6384 Commercial/Economic Division, Macdonald House, 1 Grosvenor Square, London W1K 4AB

The United Kingdom is by far Canada’s most important commercial partner in Europe and, from a global perspective, ranks second only to the United States. Two-way trade between Canada and UK was valued at more than £12 billion in 2008. The UK ranks second in Foreign Direct Investment (FDI), with UK FDI stock in Canada valued at an all time high of £22 billion in 2008. The UK is also Canada’s second largest science & technology partner worldwide, with over 40% of S&T collaborations being in the field of biomedical and clinical research. The Commercial and Economic Division of the Canadian High Commission in London works with Canadian companies, universities and research institutes that are seeking market opportunities, collaborative R&D partnerships or technology transfer deals in the UK. We also offer confidential advice and service to UK companies interested in investing in Canada or in finding collaborative opportunities with Canadian partners.

Cancer Research Technology Ltd

Sarah Austin

www.cancertechnology.com

Cancer Research Technology Ltd, Angel Building, 407 St John Street, London EC1V 4AD

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enquiries@cancertechnology.com

Tel: 020 3469 6300

CRT sources, develops and commercialises new cancer therapeutics, vaccines, diagnostics and enabling technologies. The company’s strategy is focused on both the discovery and clinical stages of the pharmaceutical development process. CRT sources novel discoveries through a network of alliances and partnerships in the UK, EU, North America (via subsidiary company CRT Inc, based in Boston) and Australia. We work closely with leading international cancer scientists and their institutes to protect intellectual property arising from their research. Discoveries are either partnered with industry for further development or progressed with translational funds either in the academic institute or in CRT’s Discovery Laboratories prior to partnering. CRT is wholly owned by Cancer Research UK, the largest independent funder of cancer research in the world.

Cancer Research UK

www.cancer.org.uk

61 Lincoln’s Inn Fields, London WC2A 3PX

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Capsugel www.capsugel.com

Tel: 01304 644791

Cambridge Research Centre, Building 4 - Granta Park, Great Abington CB21 6GP

Fax: 01223 892326

Capsugel is a global leader creating innovative dosage forms for the pharmaceutical and dietary supplements industries. Companies look to our leadership to formulate new products, enhance existing product lines, bring new products to market faster, and ensure their clinical trials are conducted without bias. In addition to it’s diverse capsule product line. Capsugel offers a range of systems for filling powder or liquid into capsules and other small dose containers: - Xcelolab™ powder dispenser: offers fast, flexible precise powder dosing for any laboratory, accurately and reproducibly dispensing tiny amounts of any powder into a variety of containers. - Xcelodose 120S and 600S precision powder micro-dosing systems: enable dispensing of active pharmaceutical ingredients (API) without the need for excipients or bulking agents. - CFS 1200 and CFS 1500 liquid capsule filling and sealing systems As an active industry supporter, Capsugel also gives presentations about dosage forms to pharmaceutical students at universities.

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Carpmaels & Ransford Sarah Kent

Carpmaels & Ransford - Patent & trade mark attorneys

skt@carpmaels.com

Our firm probably has the largest and most highly reputed team of biotech specialists in Europe. Our team is led by a number of individuals who have been practising in the field since its inception and have seen companies grow and prosper through their advice. In addition to representing global companies of considerable scale, we act for many academic institutions and small start-up life sciences companies across Europe. Working alongside the patent attorneys, we have trade mark attorneys and transactions specialists with proven expertise across all areas of trade mark work, and in transactions involving IP rights.

www.carpmaels.com

Tel: 020 7242 8692 Fax: 020 7405 4166

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Carpmaels & Ransford, One Southampton Row, London WC1B 5HA United Kingdom

One Nucleus Directory 2011

Carter Jonas www.carterjonas.co.uk Tel: 01223 368771 Fax: 01223 369950 6-8 Hills Road, Cambridge CB2 1NH

A Carter Jonas is one of the leading property consultants in the Science Park sector. The Technology Team looks after the property interests of funds, developers and occupier companies in the biotechnology and wider technology sector on a nationwide basis. Within the ERBI region, Carter Jonas act for a number of developer / investor clients on biotechnology focussed projects, including Chesterford Research Park, Cambridge, Colworth Science Park, Bedford and Norwich Research Park. We offer a broad spectrum of services to both public and private sector clients including feasibility studies, demands and needs studies, development agreements, creation of SPVâ&#x20AC;&#x2122;s, marketing strategy reports, lettings and acquisitions of incubators, laboratory and or R&D buildings in the eastern region and further afield. A multi-disciplinary practice Carter Jonas now has 31 offices in key locations in England and Wales, including London, employing 450 people with a turnover of approx ÂŁ30 million.

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CB1 Bio Ltd www.cb1bio.com 2 High Street, Histon CB24 9LG

CB1 Bio Ltd specialises in consultancy for small molecule drug discovery, from target identification and assay development to lead optimisation and preclinical studies. The areas we cover with special expertise include neuroscience, oncology and the use of zebrafish for drug discovery. We also have considerable experience in grant and home office licence application writing, FTO searches and patent preparation, outsourcing of preclinical studies and women in science.

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CellCentric www.cellcentric.co.uk

Chesterford Research Park, Little Chesterford, Cambridge CB10 1XL

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Cellexus Ltd

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Celtic Catalysts www.celticcatalysts.com Nova Centre, Belfield, Dublin, Ireland 4

Celtic Catalysts has a portfolio of internally-developed chiral technologies and the areas of chemistry in which we work falls into the following categories: Unnatural amino acid synthesis, Asymmetric catalysis, Phosphorus chemistry (particularly generating P-chirality), Enantioselective synthesis, Medicinal chemistry route development and process optimisation, Chiral HPLC method development and preparative HPLC We continue to develop our internal technologies and have experience of conducting research and contract synthesis projects for clients in pharmaceutical and biotechnology industries.

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www.onenucleus.com

Central Europe Corporate Advisors (CECA) www.ceca.pl

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ul. Pulaskiego 24, Konstancin-Jerziorna, Poland 05-510

Tony Repa, CECA’s founder, has been working and based in Warsaw Poland since 1991. Formerly senior EU advisor to the government’s privatisation programme, then head of Chase Manhattan Bank’s corporate finance practice, he now heads up CECA which works on behalf of large and small international corporate investors seeking business opportunities in Poland - mainly setting up greenfield or JV operations or seeking out new export or supply markets.

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CenTRion Therapeutics Ltd

Amanda Lyne, CEO

CenTRion Therapeutics, a spin out from the University of Greenwich, is developing novel sodium channel blocking drugs for the treatment of diseases of the central nervous system (CNS), such as epilepsy, MS and pain.

alyne@centriontherapeutics.com

The company has world class know how and IP in ‘rationally’ designed cyclic triazo and diazo based therapeutics which have the potential to address unmet needs such as long term neuro protection and is currently undergoing pre clinical research and phase 1 trials needed to demonstrate their efficacy.

H I J K

www.centriontherapeutics.com Tel: 07966 341 805 Medway Enterprise Hub, Chatham Maritime, Kent ME4 4TB

Chesterford Research Park

Katherine Maguire, Park Manager

km.chesterfordrp@btinternet.com

www.thenucleus.uk.com

Chesterford Research Park, Little Chesterford, Essex CB10 1XL

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www.chesterfordresearchpark.com

Tel: 01799 532252

Set in 250 acres of open parkland within the South Cambridgeshire Biotech Cluster, Chesterford Research Park provides a secure and relaxed working environment for R&D companies of all sizes wanting to be positioned at the epicentre of UK drug discovery. It is not only an established development, but also a growing community. The vision for the Park was to create high-quality, state-of-the-art laboratory and office space specifically designed for research and biotech companies at all stages of their life cycle. Now in its eleventh year that vision is fast becoming reality as the Park continues to attract leading R&D companies. On completion, it will comprise 600,000 square feet of R&D facilities within a low-density, landscaped environment served by state-of-the-art amenities. The central facilities building at the Park, The Nucleus, sets new standards for the provision of amenities on science park developments, including state-of-the-art conferencing facilities, health club, shop, restaurant and café bar.

Chroma Therapeutics www.chromatherapeutics.com 93 Milton Park, Abingdon OX14 4RY

Chroma Therapeutics is focused on small molecule therapeutics for cancer and autoimmune/inflammatory indications. It has 3 drugs currently in clinical development in oncology, one of which, tosedostat is currently in phase III in AML patients. It is also developing a pipeline of agents for inflammatory diseases using its proprietary ESM technology which allows the targeting of small molecule drugs to cells of the monocyte and macrophage lineage.

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CK Clinical www.ckscience.co.uk

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9 The High Street, Stevenage Old Town, SG1 3BG

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One Nucleus Directory 2011

CK Clinical is a leading clinical recruitment company handling jobs in clinical research and drug development. Our clients include some of the top Pharmaceutical and Biotechnology companies from around the world and our reputation for honest and integrity is well known. We offer contract and permanent clinical research job opportunities to both experienced professionals and entry level candidates. Here at CK Clinical we pride ourselves on our strong candidate focus. We know that looking for a job can be a stressful and difficult experience and we aim to make the process as simple and enjoyable as possible. CK Clinical is a member of the Recruitment and Employment Confederation (REC) and uphold the highest professional standards in recruitment. We pride ourselves on an ethical and transparent recruitment service and believe that integrity and honesty are the founding principles in all that we do.

Clasemont Limited 42 Apthorpe Street, Fulbourn, Cambridge CB21 5EY

A Clasemont Limited is a company providing corporate finance advice to privately owned life science companies and their shareholders, both individual and institutional. In current markets Clasemont focuses particularly on fundraisings, disposals and spinouts. Clasemont was founded in 2006 by Rob Arnold, who had previously been a corporate finance partner and European life sciences leader for PricewaterhouseCoopers, before deciding to pursue a solo career. Although Rob leads all of Clasemontâ&#x20AC;&#x2122;s assignments, he is able to assemble appropriate teams as required from a network, built up over many years, of individuals with specialist skills.

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Clinical Development and Support Services Ltd www.cdssltd.com Tel: 01625 617447 Fax: 0870 094 0730 Suite 5, Silk House, Park Green, Macclesfield SK11 7QJ

CDSS was developed in 1998 and is a dynamic expanding CRO offering a wide range of clinical development services (including contract Research Nursing) to the Pharmaceutical, Biotechnology and Medical Device industries. CDSS deals with all phases of clinical development and have extensive experience in handling large volumes of patient data. Our staff have experience in numerous therapeutic areas including:- CNS, Pain, Cardiovascular, Dermatology, Endocrinology, Genitourinary, Immunology, Oncology, Respiratory, Neurology, Surgery and Infertility.

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CMP Therapeutics www.cmptherapeutics.com BioPark, Broadwater Road, Welwyn Garden City AL7 3AX

The company is developing natural products as intranasal devices and for functional food. Completed phase II clinical trails in seasonal allergy.

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CMS Cameron McKenna www.law-now.com Tel: 020 7367 2000 Mitre House, 160 Aldersgate Street, London EC1A 4DD

CMS Cameron McKenna is full service, international law firm. The firm has a network of offices in the UK, across Europe and the Far East. We understand that the lifescience sector presents its own unique challenges and needs. As such we have a distinct team who are focused on building the links and expertise required to deliver sector specific service to our clients. This means our clients benefit from commercial no-nonsense advice whether they are longstanding clients or prospective clients needing a second opinion or advice where others are conflicted. Our clients tell us that they value our commercial advice, which is delivered at competitive prices. We are recognised leaders in the industry and have a strong track record of working with the full spectrum of companies, from earlystage spin-outs and pre-IPO companies through to major global companies.

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College Hill Life Sciences Nicole Yost Nicole.yost@collegehill.com www.collegehill.com

College Hill Life Sciences provides a full service communications consultancy focused on science-based sectors. Within the life science field College Hill has established a leadership position by working in partnership with clients to deliver high quality communications that build corporate value and promote leading edge products, technologies and services.

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Tel: 020 7457 2020

The Registry, Royal Mint Court, London EC3N 4QN

Y Z www.onenucleus.com

101

Colliers International www.colliers.com/uk

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Tel: 020 7487 1603 Fax: 020 7344 6823

Colliers CRE is part of Colliers International, a global organisation with 267 office in 57 countries able to provide local real estate advice wherever required by our clients. Our Cambridge office, led by Edward Dodson and Michael Jones provide locally based occupiers, landlords, developers and investors with a full range of commercial property transaction and consultancy services.

Bishop Bateman Court, Thompson’s Lane, Cambridge CB5 8AQ

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Colworth Park

www.colworthpark.com

Fax: 01234 782214

Tel: 01234 222441

Sharnbrook MK44 1LQ

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Colworth Science Park is a regional enterprise hub and an established location for scientific excellence in food, health and wellness, which is being developed by Unilever and global property group Goodman. Set within 1,200 acres of natural parkland, Colworth Science Park provides a supportive open innovation environment where networking and collaboration are integral to the campus culture. It is home to one of Unilever’s global research centres and over 16 small and medium size enterprises in a variety of fields which undertake cutting-edge research, prototyping and product development. These will soon be complemented by a new innovation and amenities centre, known as The Exchange. Due for completion in January 2011, it will feature modern laboratory and office suites, a café-restaurant, and state-of-the-art meeting and conferencing facilities. It will also provide a research facility for IFR Extra Ltd, part of the Institute of Food Research, and house divisions of Cranfield University and the University of Cambridge’s Institute for Manufacturing.

CompChem Solutions info@compchemsol.co.uk www.compchemsol.co.uk

Fax: 01223 249312

St John’s Innovation Centre, Cowley Rd, Cambridge CB4 0WS

CompChem SolutionsTM was founded in April 2004, to provide computational chemistry and chemoinformatics services to the biotech and pharmaceutical industrial sectors. From 2009, complementary services such as patent searching, medicinal chemistry, process R&D chemistry and pharmacology are also available. Clients range from major pharma companies through to startup companies, where CompChem Solutions’ unique business model can offer flexible access to resources and software as needed. Services offered include: • Full computational chemistry support for medicinal chemistry projects such as - • Virtual screening • Structure-based drug design • Protein homology modelling • Pharmacophore modeling • Medicinal chemistry library design • Management of lead optimisation/discovery projects • Patent searching • Support for regulatory submissions • Management of GMP/PRD phases • Pharmacology protocol design (particularly ADMET) • Pharmacological CRO selection & management

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Competitive Drug Development International Ltd Nonna Casabayo Office Manager info@cddi.co solutions@cddi.co

We are an international biotechnology and pharmaceutical consulting company, led by a full time core management team of senior people who have developed more than 30 products globally from discovery to market. Our Managing Partners personally direct a global network of people that cover a wide range of drug development expertise with skills to operate in all project areas. Since formation, we have worked with both large pharma and small biotechs, as well as with investment companies.

www.cddi.co Tel: 0207 792 6845

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CDDI Ltd, 3 Courtnell Street, London W2 5BU United Kingdom

Connect Medical Resources Ltd www.connectbio.co.uk

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Tel: 01295 272996 13 William Close, Banbury OX16 0UE

Y Z 102

One Nucleus Directory 2011

Focussed in healthcare, Connect can provide all of the support required to get a new company established. We are skilled in recruiting all types of staff at all levels. We can help with funding, board structure and appointments and sales and marketing strategy.

Constellation Technologies Ltd www.constellationtechnologies.com Rutherford Appleton Lab, Harwell Innovation Campus, Didcot OX11 0QX

Constellation provides bioinformatics IT products and services on the “cloud” to Pharma and Biotech companies using technology developed at CERN and used widely. Applications are usually large data compute and storage services/products; they include data – accessing, management and long term storage, and; compute resources – access to many thousands of cores. Specific applications are any that involve IT expertise and resources but include specifically 1. Gene sequence analysis (human, animal, plant) 2. Large data set mining (useful information from large data sets) 3. Data manipulation using statistical analysis packages Advantages to customers are; 1. Cost reduction (outsource savings).

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Consultant, Fraser Campbell

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Consultant, Mia Williams

L M N O P Consultant, Richard Garraway

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Core Cambridge info@core-cambridge.com www.core-cambridge.com Tel: 01223 429998

Core Cambridge is a centre of excellence for injury rehabilitation and the development of athletic performance. Our unique blend of therapy, coaching and facilities can free you from injury faster than you thought possible, and can develop you physically to levels that you never thought you’d be able to achieve – whether that’s improving your long-term health or competing at an international level.

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Unit K, Trinity Hall Farm Estate, Nuffield Road, Cambridge CB4 1TG

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Covance Clinical Development www.covance.com

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7 Roxborough Way, Maidenhead SL6 3UD

Covance Inc., with headquarters in Princeton, New Jersey, is one of the worldâ&#x20AC;&#x2122;s largest and most comprehensive drug development services companies with global operations in 18 countries, and approximately 6,700 employees worldwide. Covance provides innovative solutions to your drug development challenges, enabling you to make crucial decisions, maximise economic objectives and speed time to market. With expertise and experience in every phase of drug development and the ability to conduct drug trials around the world, Covance is a recognised industry leader. Services include all aspects of preclinical and early clinical testing (toxicology, pharmacology and DMPK), and comprehensive clinical trial management services from phase I-IV.

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Creative Marketing and Research Ltd

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Crescent Diagnostics Ernest Poku info@crescentds.com

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www.crescentds.com Tel: 020 7558 8795 Crescent Diagnostics, Studio 5, 155 Commercial Street, London E1 6BJ

Crescent Diagnostics Ltd. is a venture capital backed diagnostics research and development company focused on developing a new predictive test for osteoporosis fracture risk, based on analysing human nail structure using a low-cost Raman spectroscopy based technique. Osteoporotic hip fracture is a serious health outcome which have a motality rate of over 20% within the first 12 months. Osteoporosis will affect 50% of all women in their lifetime. The company collaborates with biobanks around the world to conduct its clinical trials using longitudinal data. The companyâ&#x20AC;&#x2122;s prognostic solution consists of a unique combination of benchtop laboratory equipment, a nail sample carrier and proprietary algorithms to deliver the prognosis.

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Cyprotex Discovery www.cyprotex.com 15 Beech Lane, Macclesfield SK10 2DR

Cyprotex is a world renowned preclinical discovery/development contract research organisation with a core focus in analysing the ADMET/PK properties of potential new drugs.

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David Eichler Consultancy Ltd Dr David Eichler

eichler@btinternet.com Tel: 01780 480268

Stamford, Leicestershire

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One Nucleus Directory 2011

More than 30 years experience in non-clinical drug safety, including 22 years with the UK affiliate of F. HoffmannLa Roche and 10 years as an independent consultant. Principally involved at Roche in development of pharmaceuticals for global registration, including preparation for first exposure in man, programme planning and execution of regulatory and investigatory studies, NDA documentation and defence to health authorities worldwide. Major achievements include full (non-clinical safety) development of Vascace, Vascace Plus, Posicor, and Tamiflu, and the early phase development of Invirase. Services include writing research reports and regulatory documentation; independent evaluation of non-clinical dossiers; due diligence; peer review of documentation; design of studies and programmes; attachment to drug development project teams; setting up/monitoring non-clinical safety studies at CROs; literature reviews.

De Facto Communications

www.defacto.com

De Facto Communications, an integrated and long established brand within the Bell Pottinger Group, is a full service healthcare and life science communications agency. Its services include advocacy, corporate/trade/ technical media communications, financial communications, issues and crisis management, messaging, branding, digital and marketing comunications support. The agency is supported by Pelham Bell Pottinger and Bell Pottinger Public Affairs for investor relations and Governmnet relations services.

Tel: 0207 861 3019

The agency provides bespoke teams of dedicated personnel whose expertise are tailored to specific account work.

Tristan Jervis t.jervis@defacto.com info@defacto.com

De Facto Communications, The Bell Pottinger Group, 6th Floor, Holborn Gate,330 High Holborn, London WC1V 7QD

De Facto Communications’ offices are based in London with Bell Pottinger Group offices located in Europe, USA and the Middle East.

www.deliverplus.co.uk Tel: 0845 500 1050 1 Spruce House, Durham Wharf Drive, Brentford TW8 8HR

Deliver Plus offers both UK and International express courier delivery. ERBI members have access to extremely competitive courier tariffs with Deliver Plus, offering savings of up to 70%. Benefits include: • Online web login, enabling you or anyone in your organization to process and track shipments. • The combined services of UPS, FedEx and DHL under one umbrella. • A complete parcel management service, pro-actively tracking, monitoring and resolving delays on your behalf. • A dedicated, named account manager, with a direct dial telephone number. • Deliver Plus offers a completely portfolio of services, import, export, express, timed and economy delivery to over 220 countries worldwide.

www.delta-consultants.com Tel: 01480 495047 The Old Courthouse, Priory Road, St Ives, Cambridgeshire PE27 5BB

G H I J K

Delta Consultants diane@delta-consultants.com

For more information on how Deliver Plus can add value to your organization, please call us on 0845 5001050.

Diane Swain

Deliver Plus Limited Roger Sumner-Rivers

Based in St Ives, Cambs, and covering the UK and Europe, Delta Consultants Scientific and Medical Recruitment offer staffing solutions to the scientific community.

Constantly evolving, Delta recruit for customer facing roles in the sales, marketing and service areas while also having in-house expertise to help fill those more technical, administrative or executive roles that require a scientific background.

Delta offer 22 years of operation and over 75 years of industry recruiting experience to ensure that, along with our “Can Do” attitude, we are able to give the best possible chance of success to assignments entrusted to us.

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Department of Health

www.nihr.ac.uk 79 Whitehall, London SW1A 2NS

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Diamond Pharma Services Ltd info@diamondpharmaservices.com www.diamondpharmaservices.com Tel: 01279 441616 Fax: 01279 418964 Gemini House, Flex Meadow, Harlow CM19 5TJ

Diamond Pharma Services provides technical and scientific expertise to the Pharma and biotech industry through its dedicated group of 19 employees in the following areas: REGULATORY AFFAIRS DRUG SAFETY/ PHARMACOVIGILANCE COMPLIANCE/QUALITY Diamond Pharma Services specialises at providing support for smaller companies, particularly in the biotech and gene therapy sectors, by supporting companies based in Europe and North America and providing European technical expertise to support their development projects, planning and guiding the regulatory path through EMEA and other EU authorities, and ongoing support for marketed products across some or all of the above disciplines. Diamond Pharma Services was founded in 2005 by Dr Maureen Graham, formerly European Director of Regulatory Affairs at Amgen, and is supported by a team of people with broad and varied industry experience across all sectors, thus bringing a wide range of knowledge and skills to your business.

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www.onenucleus.com

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The Digital Office Richard Kirby

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richard.k@thedigitaloffice.co.uk www.thedigitaloffice.co.uk Tel: 01462 810071 The Digital Office (UK) Ltd, Manor Farm, Upper Stondon, Bedfordshire SG16 6LJ

TDO supply to the whole market place, the complete range of Ricoh products from copiers, MFDs, printers, scanners to software and audit devices. TDO is unique in it’s relationship with Ricoh, our product manufacturers. Ricoh, for the last 12 years, service all our machines in the field on a nationwide basis. It is an ideal relationship that ensures the best people with the maximum resource perform the most professional of service to you our clients. We provide to you a complete holistic approach to all your needs with a friendly local interface with over 30 years of experience in the industry.

Doubletree by Hilton Cambridge

Gayle Martin, Sales & Marketing Manager

H I J K L

gayle.martin@hilton.com www.doubletreecambridge.com Tel: 01223 259988 Granta Place, Mill Lane, Cambridge CB2 1RT

Surrounded by the historic sights of Cambridge the hotel is situated in anenviable position on the banks of the River Cam, boasting some of the best views Cambridge has to offer but only a few minutes’ walk from the centre of the city. With first class facilities for all occasions, business and pleasure, the hotel offers 122 contemporary bedrooms, a stylish Penthouse Suite, Riverside Brasserie, Twist Bar and Lounge, LivingWell health club and seven stylish conference rooms for up to 150 delegates. All bedrooms have been refurbished in a contemporary style with amazing use of light and space. Each offers airconditioning, a king size bed, Wi-Fi internet, plasma TV, mini bar and laptop safe. Why not host you event in one of seven stylish banqueting and meeting rooms, offering views of the River Cam and equipped with state-of-art audio-visual and communication technology organisers and delegates will have all the facilities they need for a productive and enjoyable event. Cambridge station is just a mile away and both Cambridge Airport and the M11 are only 3 miles from the hotel.

Drugmoldesign www.marquiswhoswho.net/ alandavidborthwick

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Senior Manager and successful Drug Designer / Medicinal Chemist now working as a consultant with considerable experience in the pharmaceutical industry. Accomplished in project management of multidiscipline research efforts, taking discovery leads to drug candidates. Innovative and creative illustrated by successes in 5 therapeutic area’s: Cardiovascular, Antiviral, Antibacterial, CNS and Pre-term Labour.Accomplished in organising collaborations, writing patents, publishing research papers / reviews and in delivering lectures on drug discovery to international conferences www.marquiswhoswho.net/alandavidborthwick

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EBD Group Philip LEDGER PhD

pledger@ebdgroup.com

Tel: 07768 217 607

www.ebdgroup.com

EBD Group AG, eethovenstrasse 47, 8002 Zurich Switzerland

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13 Burford Wharf Appts, 3 Cam Road, London E15 2SG

Y Z 106

EBD Group’s leading partnering conferences include BIO-Europe, BIO-Europe Spring®, BioPharm America™, ChinaBio® Partnering Forum, Biotech Showcase™. These events leverage the power of partneringONE®, EBD Group’s sophisticated webbased partnering system, which is also used by over 20 third-party events around the world. EBD Group is the leading partnering firm for the global biotechnology industry. Since 1993, life science companies worldwide have relied on EBD Group’s partnering conferences, technology, services and consultants to identify opportunities for collaboration and develop strategic relationships. EBD Group’s leading partnering conferences include BIO-Europe, BIO-Europe Spring®, BioPharm America™, ChinaBio® Partnering Forum, Biotech Showcase™. These events leverage the power of partneringONE®, EBD Group’s sophisticated webbased partnering system, which is also used by over 20 third-party events around the world.

Ecron Acunova Limited www.ecronacunova.com

EBD Group is the leading partnering firm for the global biotechnology industry. Since 1993, life science companies worldwide have relied on EBD Group’s partnering conferences, technology, services and consultants to identify opportunities for collaboration and develop strategic relationships.

One Nucleus Directory 2011

Manipal AcuNova, “India’s No 1 Emerging CRO**” is a venture between the Manipal Group and AcuNova. We conduct Phase I – IV Clinical Research and Bio -Availability/Bio Equivalence Studies to pharma, biotech and drug companies. We provide to CRO’s services like Clinical Data Management, Central Lab and Core Imaging. The company’s research facilities are located at Bangalore, Mangalore and Manipal. Manipal AcuNova has wholly owned subsidiaries in US and UK.

EG Technology Ltd info@egtechnology.co.uk www.egtechnology.co.uk Tel: 01223 710799 Fax: 0870 7877021 Burleigh House, 13 - 15 Newmarket Road, Cambridge CB5 8EG

A EG Technology is growing into one of the UK’s leading product engineering consultancies. Whether we are working with a small biotechnology start-up or an industry-leading blue-chip, our clients receive a level of service that forms the foundation for a long-term relationship. Based at the heart of the Cambridge technology cluster, we work with companies worldwide to develop engineering solutions to specific product needs. We don’t simply ‘solve problems’ - our experience ensures that we solve the right problems, managing risks and reducing time to market. Our team consists of bright, experienced, can-do people from a variety of backgrounds and disciplines, working together to create ideas - and turn them into reality. eg technology bring the engineering expertise to transform ideas into successful products. Our pragmatic approach combines innovation and experience to quickly and cost-effectively deliver: step-change innovation product design engineering development prototyping and testing risk reduction transfer to manufacture

Erl Wood, Sunninghill Road, Windlesham GU20 6PH

Lilly is developing a growing portfolio of best in class pharmaceutical products by applying the latest research from our own laboratories and from collaborations with eminent scientific organisations worldwide. In 2003 the company’s world-wide sales were more than $12 billion. Lilly employs more than 43000 people worlwide and markets medicines in 158 countries. Lilly Research Laboratories (the R&D division of the company) employs more than 8000 people from a wide variety of disciplines. The company has R&D facilities in 9 countries and currently conducts clinical trials in more then 60 countries around the world. Lilly’s internal research efforts are focused in the following major therapeutic areas: cancer, cardiovascular diseases, endocrinology, neuroscience, gene regulation, bone biology, immunomodulation and Inflammation Compounds in late stage development, and those currently being launched have promise to address the needs of patients with sepsis, cancer, diabetes, depression, osteoporosis, erectile dysfunction, urinary incontinence and attention deficit hyperactivity disorder. In pursuit of innovation Lilly seeks to incorporate those cutting edge technologies which support the high quality, rapid identification and investigation of novel compounds. The company approach to innovation includes a commitment to the philosophy of “ research without walls” - a stated commitment to partnership and external collaboration. Currently Lilly Research Laboratories has more than 120 active collaborations with external scientists.

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Elkington and Fife LLP www.elkfife.com

Eli Lilly and Co. www.lilly.com

Elkington and Fife is a leading firm of patent attorneys and trade mark attorneys with offices conveniently situated in central London and Sevenoaks, Kent. Our partners are acknowledged experts in their fields and have a good understanding of how intellectual property is best used by commercial and industrial organisations, having either worked in industry or worked closely with businesses. We work in all areas of intellectual property, including patents, SPCs, trademarks and designs. We give clear advice, practical solutions and advise with an appreciation of the commercial background rather than from a narrow legal standpoint.

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EMBL-EBI www.ebi.ac.uk/industry

The mission of EMBL-EBI is to: provide freely available data and bioinformatics services to all facets of the scientific community in ways that promote scientific progress; contribute to the advancement of biology through basic investigator-driven research in bioinformatics; provide advanced bioinformatics training to scientists at all levels; and help disseminate cutting-edge technologies to industry The research and service activities of EMBL-EBI span the entire spectrum of life science and remain at the cutting edge of the computational sciences. All our major data resources are the products of international collaborations. We work with other data providers to ensure that our data repositories, and those of our collaborators, are comprehensive and up to date. We also actively participate in international efforts to develop data standards. The EMBL-EBI Industry Programme engages our industrial users with the latest bioinformatics research, service development, standards activities, pre-competitive opportunities and training (www.ebi.ac.uk/industry).

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Enjay Services Ltd info@enjayservices.com www.enjayservices.ltd.uk Tel: 01354 657001 Fax: 01354 657218

We are an independently owned company, with more than 25 years experience in the service and repair of life science instrumentation manufactured by Packard Bioscience of Downers Grove, Illinois (now owned by and marketed by PerkinElmer). We can service almost the entire original Packard range, including products no longer marketed by PerkinElmer. We are proud of our fast response times and rapid repairs, which result in lower costs for our customers. We also offer on-site customer training and a consultancy service (see our website for more details).

P O Box 82, March, Cambridgeshire

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EOStrat Dr Claire Struthers-Semple

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css@eostrat.com Tel: 07880 600 362 Bartholomew Manor, Argyle Rd, Newbury, Berkshire RG14 6BZ

EOStrat offers you access to a highly experienced, multi-disciplinary Virtual Project Team to assist you in developing your new drug. We offer strategic advice in the planning stages, experienced operational resource in the implementation stages and robust issue resolution throughout the lifecycle. After an initial meeting to fully understand the scope, an EOStrat team, to fit your needs, will be compiled. All team members have >20y drug development experience and are flexible and entrepreneurial in their approach. We know what is needed and what is possible in drug development.

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Epistem ltd

info@epistem.co.uk

Tel: 0161 606 7258

48 Grafton Street, Manchester M13 9XX

www.epistem.co.uk

Fax: 0161 606 7348

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ERGOMEDClinical Research Ltd Marco Bocci Marco.Bocci@ergomed-cro.com

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www.ergomed-cro.com Tel: 01223 370111 Ergomed Clinical Research Ltd, Sheraton House, Castle Park, Cambridge CB3 0AX United Kingdom

ERGOMED is a European Clinical Development Company, providing consultancy and full clinical trial-related services as well as co-development partnerships which share the risks and rewards of clinical development. ERGOMED is also well placed to assist emerging and developing biotech and pharma companies by consulting them on strategic clinical development, pre and post-marketing pharmacovigilance and regulatory affaires. ERGOMED conducts operations throughout Europe and North America with special focus on Central and Eastern European countries and the MENA (Middle East and North Africa) region.

Europa Bioproducts Ltd info@europa-bioproducts.com

www.europa-bioproducts.com

Fax: 01353 624589

Epistem is a biotechnology company commercialising its expertise in epithelial stem cells in the areas of oncology, gastrointestinal diseases and dermatology. Epistemâ&#x20AC;&#x2122;s Contract Research Division has a track record of providing bespoke preclinical efficacy testing services to over 130 international clients in biotechnology, pharmaceutical and personal care sectors. Through specialist knowledge of epithelial diseases, the scientists at Epistem have developed a range of unique in vitro and in vivo assay methodologies which can be used to assess the mode of action and efficacy of new drug candidates. The information generated can assist in project decision-making and strategic planning for a variety of drug development programmes. With expertise in disorders of intestinal, skin and oral epithelia, as well as a strong oncology focus, Epistem screens new compounds to assess their potential as anti-cancer agents, IBD agents, mucositis modulatory agents, cell cycle stimulators or inhibitors and wound healing regulators. Novel services that Epistem has recently introduced into its research service portfolio include an adoptive T-cell transfer IBD model, in vitro and in vivo cancer stem cell and angiogenesis assays and a unique plucked hair follicle cancer biomarker platform with preclinical and clinical applications.

Tel: 01353 721118

Our main business is the supply of the GLYKO range of glycobiology reagents manufactured by ProZyme Inc. They are used in the characterisation of glycans associated with recombinant proteins. We supply all of the European Biopharmaceutical companies with one or more products. We supply a range of fluorescent proteins and conjugates used in flow cytometry, FRET technology and multiplexing applications. We use our Ecommerce web site to supply these same products to researchers throughout Europe.

15-17 North Street, Wicken, Ely CB7 5XW

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Evotec UK Ltd Angela Burt

info@evotec.com www.evotec.com

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Tel: 01235 861561 Evotec (UK) Ltd, 114 Milton Park, Abingdon, Oxfordshire OX14 4SA United Kingdom

One Nucleus Directory 2011

Evotec is a leader in the discovery and development of novel small molecule drugs with operational sites in Europe and Asia. The Company has built substantial drug discovery expertise and an industrialised platform that can drive new innovative small molecule compounds into the clinic. In addition, Evotec has built a deep internal knowledge base in the treatment of diseases related to neuroscience, pain, oncology, inflammation and metabolic diseases. Leveraging these skills and expertise the Company intends to develop best-in-class differentiated therapeutics and deliver superior science-driven discovery alliances with pharmaceutical and biotechnology companies.

Expedeon Protein Solutions Ltd info@expedeon.com www.expedeon.com Tel: 01223 873364

Expedeon manufactures and supplies novel and innovative products for use in protein research. Expedeon is a rapidly expanding company offering products for; - protein electrophoresis - protein purification - protein quantitation - protein stabilisation - protein refolding. In 2009 Expedeon’s RunBlue pre-cast PAGE gels were included in the successful Sigma Aldrich bid for ERBI Preferred Supplier status.

Fax: 01223 873371 Unit 1A, Button End, Harston, Cambridge CB22 7GX

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Field Fisher Waterhouse LLP www.ffw.com 35 Vine Street, London EC3N 2AA

Field Fisher Waterhouse is a UK Top 30 law firm with over 130 partners and over 260 other lawyers offering the full range of legal services. Life sciences clients choose to work with us because we have a substantial team of exceptional lawyers, each with their particular specialism, but who at the same time know the major commercial, legal and regulatory issues affecting this industry sector. They also appreciate that when we say full service, we really can deliver on all counts, be it advising on regulatory matters, corporate and commercial issues, IP licensing and litigation, competition law issues, compliance with data privacy requirements, complex tax arrangements, trade marks, employment and real estate. Through our network of offices in London, Manchester, Brussels, Hamburg and Paris our clients understand that they will get real value from our flexible approach to teamwork and our willingness to shape our structures and way of working to meet their specific needs. This commercial attitude, combined with our empowering and down-to earth style, means you can trust us to provide you with the best possible legal solutions. One of our key strengths is our focus on industry sectors such as life sciences, with expertise in the pharmaceutical, biotechnology and medical devices industries. By pooling our expertise in the life sciences sector across different legal disciplines and our European offices into an industry group, we can provide you with a joined-up approach to your legal issues. It enables us to keep up-to-date with developments in the sector, delivering realistic and practical solutions to our clients’ issues. Many of our lawyers have a scientific or medical background. This enables us quickly to understand the technology that underpins, and gives value to, our life sciences clients’ businesses. Our Life Sciences group works with clients at all stages of innovation, from bench to bedside and helps companies to develop and grow their businesses within the strict regulatory requirements that can apply in this sector. During the various stages of growth our lawyers help pharmaceuticals clients with: regulatory compliance, approval and issues arising with competent authorities licensing, collaboration and marketing agreements patent litigation data protection and privacy trade mark registration and litigation clinical trial agreements and regulation supply, distribution, manufacturing and tooling agreements corporate finance and M&A competition & EU regulatory (including REACH) outsourcing projects and services real estate, employment and pensions tax planning and valuation.

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Fire Safety Services

enquiries@firesafetyservices.co.uk www.firesafetyservices.co.uk

Tel: 01603 73199 Fax: 01603 749089

Unit 1 Robberds Way, Bowthorpe, Norwich NR5 9JF

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First Ascent Consultancy Ltd www.firstascentgroup.com 5 Wellingley Court, Lower Cambourne, Cambridge CB23 7EQ

Clients describe us as the most dynamic and engaged organisation in our field! Our expertise includes: leadership development, team performance development, management development, team building, coaching, talent and graduate development. Our uniquely experienced team of programme directors support you with energy, understanding and challenge. We offer mentoring to all our alumni .... for life .... for free. First Ascent service is personal, flexible and responsive. We live your challenges alongside you!

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Fisher BioServices www.fisherbioservices.com Tel: 01279 713320 Fax: 01279 713329 1 Woodside, Bishop’s Stortford CM23 5RG

V Fisher BioServices – your Critical Material in Safe Hands Part of Thermo Fisher Scientific, Fisher BioServices are experts in clinical trial supply, specialising in clinical services for Phase I to IV trials through to commercial supplies, biorepository services & cold chain logistics. Understanding the special needs involved in clinical studies and in the research and development process, we provide secure, controlled temperature storage, sample collection kit assembly, sample processing and logistics. We are licensed by the HTA, MHRA and HFEA and have ISO9001:2000 accreditation. Our key services include:

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• Import of supplies into the European Union • Qualified Person services • Secondary packaging • Labelling and assembly • Storage at all temperatures • Worldwide distribution • Returns and reconciliation

From our site in the UK, our facilities, systems and procedures are professionally managed and are regularly audited by the Medicines and Healthcare Regulatory Agency (MHRA), our clients, and other regulatory bodies worldwide.

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Fisher Scientific UK www.fisher.co.uk

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Tel:01509 231166 Fax:01509 231893 Bishop Meadow Road, Loughborough LE11 5RG

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Forecast Flow

Lynn Munday

www.forecastflow.co.uk

107 New Road, Chatteris, Cambridge PE16 6BT

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info@forecastflow.co.uk

Tel: 0845 873 0540

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Forecast Flow helps start ups and SMEs in the technology sector take control of their financial future by providing operational and financial management tools which are appropriate to each business. All companies should put in good financial systems, controls and reporting from day one. The services provided by Forecast Flow can help address this by providing budgets, forecasts, management accounts, cash flow forecasts for your reporting needs and help with systems and controls including the installation of accounts packages. In addition for SMEs Forecast Flow can provide businesses with the in house expertise of a part time Finance Manager.

Forresters Charlotte Dale cdale@forresters.co.uk

Fisher Scientific is a world-leading supplier of laboratory chemicals, consumables and equipment to the scientific community. Fisher Scientific realises that it’s future lies within the biotechnology sector and indeed, building relationships with networks such as ERBI. Fisher Scientific, therefore, recognises the need to support such important initiatives and take it’s role within these arrangements very seriously. As part of Fisher Scientific’s strategy, it looks to support the members of the ERBI community with specific offers and services designed for scientists and researchers within the biotechnology areas. Examples of these initiatives are: • Dedicated pricing and support on all chemicals, consumables and equipment to all ERBI members. • The new Lab Start-up Program: designed to help scientists give the start that their laboratory deserves. Over 30 different suppliers with over 70 different offers can help a new lab save over £50,000. As a member of the Lab Start-Up scheme, Fisher Scientific can assist with… Selection, purchasing, and delivery of all product requirements. - Planning and design of a new lab. - Tracking the participants’ Lab Start-Up spend - As a Lab Start-up member, they will automatically be entitled to lots of additional discounts, special offers, dedicated support plus much more. • bioSolutions: A twice-yearly brochure, in collaboration with world leading manufacturers’ designed to give up to date information on new products and promotions. • Specific offers aimed at the biotech sector. Investment in intelligent Customer Relationship Management software enables Fisher Scientific to be very specific in what it promotes to the individual, ensuring that person only receives what is relevant to them. Working with ERBI to bring their members the best in terms of service, support, value for money and high quality products has been hugely successful. Fisher Scientific look forward to working closely with ERBI and acting on their members needs to ensure the company continues to meet and exceed customer requirements for the future. Fisher Scientific is now part of the Thermo Fisher Group, the world’s largest manufacturer and supplier of products to the scientific community. For more information please visit www.fisher.co.uk

www.forresters.co.uk Tel: 020 8889 6622 Forresters, Forrester House, 52 Bounds Green Road, London N11 2EY

At Forresters, we provide clear, sensible and practical advice on intellectual property, including patents, trade marks, designs and copyright, in the UK and across the world. We like to take a collaborative approach with our clients, drawing on their knowledge to ensure that we understand what they want to achieve. We look to deliver our guidance in plain, jargon-free language and are not afraid to recommend a particular course of action, if we think it is right for you. We have a well-established and sizeable life-sciences department, with extensive experience in getting and litigating patents in the UK and Europe.

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G-S Consultants Tel: 020 842 2931 44 Aintree Avenue, London E6 1NX

Analytical development CMC Project Management, Laboratory set up, freeze drying, solid dose manufacture, technical trouble shooting in the areas of Cell Culture, Molecular Biology, Microbiology and Biochemistry.

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GB Innomech Ltd Steve Robertson

info@innomech.co.uk www.innomech.co.uk

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Tel: 01353 667394 The Innovation Centre, Common Road, Witchford, Ely, Cambridgeshire CB6 2HZ

One Nucleus Directory 2011

GB Innomech helps organisations in the pharmaceutical and medical device sectors to manufacture and/or inspect their products through automation. We are experienced with early stage development and with existing products and processes. We are able to offer a number of technologies including: • precision handling and placing • laser • precision gluing • precision welding • micro dispensing of liquids • micro dispensing of powders • multi-axis servo systems • design of intelligent control systems • vision and inspection technologies A thorough knowledge of these technologies enables us to automate even the most complex, highly labour intensive manufacturing, inspection or testing processes. Our systems are used by most of the world’s leading pharmaceutical companies, as well as many biotech and contract manufacturers. Our work is undertaken within an ISO 9001:2008 environment and our processes are based upon GxP practice.

GE Healthcare www.gehealthcare.com/uken/ Tel: 08702 407575 Fax: 08702 407534 Amersham Place, Little Chalfront HP7 9NA

A GE Healthcare provides transformational medical technologies and services that are shaping a new age of patient care. Our expertise in medical imaging and information technologies, medical diagnostics, patient monitoring systems, performance improvement, drug discovery, and biopharmaceutical manufacturing technologies is helping clinicians around the world re-imagine new ways to predict, diagnose, inform, treat and monitor disease, so patients can live their lives to the fullest. Scientific Asset Services from GE Healthcare offers a comprehensive life cycle asset management solution, going beyond equipment maintenance and designed to help Companies improve productivity while reducing costs. GE Healthcare customized programs can offer solutions for pre-purchase planning and predictive maintenance, as well as managing moves, redeployment and disposal of equipment. Data from the program is used by GE Healthcare to provide business intelligence that helps drive informed decision making. With 15 years of understanding life cycle asset management coupled with a global reach, change management and Lean Six Sigma skills, GE Healthcare delivers a consistent solution where companies need it.

Through novel approaches in genomics and bioinformatics the centre foucuses on the analysis of plant, animal and microbial genomes to improve food security, protect UK agricuture from exotic animal disease and exploit weaknesses in microbes to develop new ways to kill superbugs. TGAC partners with industry and non-commercial customers in genomics projects across three broad application sectors: • Agricultural - including food security, food processing and animal husbandry • Nutrition and ‘wellness’ • Sustainable energy, and bio-processing including bio-pharmaceuticals TGAC is committed to makings its facilities available to UK companies that could benefit from using advanced genomic approaches and its trading subsidiary, Genome Enterprise Limited, manages its engagement with commercial clients.

Rachael Spooner

The Genome Analysis Centre applies genomics and bioinformatics to key strategic areas of biological science.

tgac.enquiries@bbsrc.ac.uk

TGAC delivers projects with industry and non-commercial partners for:

www.tgac.bbsrc.ac.uk

• Animal health • Microbes and viruses

Hotley Bottom Barn, Great Missenden HP16 9PL

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• Crop production • Environment

TGAC is committed to making its facilities available to UK companies that benefit from using advanced genomic approaches and its trading subsidiary Genome Enterprise Limited, manages its engagement with commercial clients.

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George James Ltd www.georgejamesltd.co.uk

The Genome Analysis Centre (TGAC)

The Genome Analysis Centre, Norwich Research Park, Colney, Norwich, Norfolk NR4 7UH

The Genome Analysis Centre (TGAC)

Tel: 01603 450861

George James adds value to businesses through its expert services in recruitment and talent management. We have a combined experience of over 150 years in the business areas we support and over 50 years as a service provider. We have a global reach and work extensively throughout Europe and we also network into the US & Canada via our strategic partners. What makes george james unique are our flexible approaches that allows us to employ proactive search strategies at all levels not just senior appointments. Thus we can offer effective solutions to reduce the lost opportunity costs for business critical hires that may have no solution or take many months with less proactive approaches.

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Giles Insurance Brokers Ltd

www.thebroker.co.uk

12 Poverest Road, Orpington BR5 2TP

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Global Regulatory Services Mrs Greer Deal, Director

greer@globalregulatory services.com

www.globalregulatoryservices.com

Global House, Painters Lane, Sutton, Ely, Cambridgeshire CB6 2NS

Tel: 01353 774000

GoIndustry DoveBid

www.go-dove.com

1-6 Lombard Street, London EC3V 9JU

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Global Regulatory Services (GRS) is a UK based consultancy offering resource, support, advice and solutions to life-science and healthcare companies worldwide (with a focus on regulatory affairs and innovation). With a global network of several thousand high calibre professionals and specialists, we can provide strategic advice as well as ensuring compliance with all the current and relevant rules and regulations. The company is well placed to support companies with emerging, novel products and technologies from herbals to stem cell therapy and devices to borderline products. We enjoy the challenges presented in taking our clients’ innovative products from lab to market.

GoIndustry DoveBid is a leading provider of asset management services. If surplus or idle assets are no longer needed, we can help you understand what they are worth, whether they can be re-deployed elsewhere in your organisation, and if not, sell them at auction on your behalf. GoIndustry DoveBid approaches the market with three distinct advantages. First, we have significant global reach so we are able to provide these services wherever they are needed. Second, most of our business is online, making it more efficient and convenient for both buyers and sellers whether it’s for a single piece of equipment or a whole production line. Third, our knowledge of the market across multiple industry sectors is unsurpassed. Since 2000, we have collected information gathered from auctions all over the world, numbering over 1500 in 2007 alone. We leverage this rich data on a daily basis through accurate valuations and appraisals for the benefit of all our customers. Our customers fall into five categories: • Multinational manufacturing corporations with whom we have long term forward flow contracts to provide a range of asset management solutions • Asset based lenders, financial institutions and banks who require our valuation services in order for them to put the right numbers on the value of equipment, inventory and receivables • Bankruptcy and insolvency practitioners, who need our services to help them clear factories • Small-to-medium enterprises, for whom we provide a variety of asset management and valuation services • Dealers, with whom we work to increase the flow of assets to our auction sales Each engagement features an evaluation of your assets to help you make sound financial decisions. To ensure that your company gets the maximum return on its investment and the quickest route to sale, we will: • Determine the best sales channel such as online auction, live and webcast auction, industry specific online Exchange, or sale by Private Treaty. • Support your asset sale with extensive marketing resources, technology and tactics, which make the most of the global marketplace. • Facilitate the sale with cuttingedge Internet technology that streamlines the buying process.

GOLD Biosciences

Tel: 0141 3341656

• GOLD develops novel oxygen carriers and specialized software for use with MRI.

206 St Vincent Street, Glasgow, G2 5SG UK

• Lead product is a synergistic diagnostic / therapeutic.

• Lead indication is acute stroke; cardiovascular, oncology and epilepsy pipeline.

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GrahamJeffery.com Graham Jeffery

graham@grahamjeffery.com

Tel: 07785 378 512

www.grahamjeffery.com

PO Box 45703, London SW16 2YX

I am an independent strategy consultant and decision analyst, which means I help pharmaceutical and biotech client make the big one-off strategic decisions that determine their future. I can help you: • identify the risks and opportunities—the possibilities and their probabilities • forecast how that uncertainty will affect value—the things you care most about • evaluate how what you can do—the decisions you face—will affect both uncertainty and value • decide and commit to your best course of action. I help people make high-quality decisions in the face of uncertainty.

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Gram UK Scott Gibson

scgi@gram-bioline.com www.gram-bioline.com

Tel: 01322 616900

2 The Technology Centre, London Road, Swanley BR8 7AG

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One Nucleus Directory 2011

Gram BioLine refrigeration for scientific & medical applications where temperature control, energy efficiency and green production values are important. Designed for lab needs, built to exceed!

Great Eastern Investment Forum (GEIF) geif@nwbrown.co.uk www.geif.co.uk Tel: 01223 345616 Fax: 01223 345617 Ravenscroft House, 61 Regent Street, Cambridge CB2 1AB

The Great Eastern Investment Forum (GEIF) was established by Nigel Brown in 1995, and is one of the UK’s premier business angel networks. GEIF works with both early stage technology companies and later stage ‘non-tech’ businesses helping to attract investment from its members, typically in the range of £100k to £1.5m. GEIF has a diverse range of investor members with a wide range of knowledge and experience in a variety of sectors. Its members have invested in many successful businesses including Artimi, Camrivox, Coffee Nation, DanioLabs, Novacta Biosystems, OnRelay, Revieworld and Quotient Diagnostics. The primary method of introduction between companies seeking funding and the business angels is a Presentation Day, when up to six companies are given an opportunity to present to the GEIF business angels. Companies applying to GEIF represent a range of sectors, including biotech. In addition, GEIF holds a series of quarterly breakfast meetings with keynote speakers, focussing on topics of interest to the wider investment community. The ongoing quarterly breakfast meetings continue to attract a high-quality audience from the investment community, with keynote speakers such as Edward P. Gibson, Chief Security Adviser Microsoft UK. Funding Opportunity GEIF welcomes applications from a wide sector of companies seeking business angel funding of between £100K - £1.5million. To be selected as one of the presenting companies at a Presentation Day, all applicants have to proceed through a two-stage application process, which is free of charge. Once a company is selected, an initial fee is incurred followed at a later stage by a success fee should the company be successful in sourcing funding from the GEIF angels. Applicants should send a full business plan to arabella.wright@geif.co.uk. Full details and costs can be found on www.geif.co.uk.

www.greatspur.co.uk Tel: 01953 714942 Fax: 01953 714942 42 Kenninghall Road, East Harling, Norwich N16 2QD

Greatspur Clinical Development Limited is a small, privately owned Limited Company providing a range of advice and support services to pharmaceutical and biotechnology companies on the planning, preparation and conduct of clinical trials. Working with clients from the late pre-clinical stage to develop and manage Phase I trials, Greatspur can provide product development and clinical trials support throughout the development process. The company can offer in-depth knowledge and experience of the clinical research environment and a network of regulatory and other industry associates. Services include project management, medical writing and quality management services, including clinical systems and procedures development and support for regulatory inspections. Our aim is to deliver a professional service tailored to our clients’ needs, coupled with a commitment to high quality and timely delivery.

www.gf-associates.co.uk Tel: 01353 645590 Fax: 01353 645599 30 St Thomas Place, Cambridge Business Park, Ely CB7 4EX

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Gregory Fryer Associates Ltd info@gf-associates.co.uk

Greatspur Clinical Development Ltd enquiries@greatspur.co.uk

GFA is an expert regulatory, clinical research and GCP QA contract company, providing practical advice and support to the biopharma industry to move products from early concept, into the clinic and on to Marketing Authorisation. Our range of services includes: Agency meetings and briefing document preparation, clinical trial approvals, Orphan Drug applications, MAA, Clinical trial management and monitoring, GCP QA audits and SOP writing, medical writing, US Resident Agent services and EEA Legal Representative services. GFA has an excellent understanding of the global regulatory arena, and with staff in the UK and USA, GFA supports in particular European companies seeking to expand development to the US but also US companies coming to Europe. What sets us apart is our combination of both clinical and regulatory expertise within the one consultancy group, allowing a comprehensive approach to product development encompassing the needs of regulatory requirements and the clinical research process.

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Grundon Waste Management Limited clinical@grundon.com www.grundon.com Tel: 01628 501590 Fax: 01628 501590

Established in 1929, we are proud to be the largest family run waste management company in the UK. We have developed our service over the years to specialise in establishments that require a high level of expertise and technical knowledge. We have established a large customer base of scientific research companies providing consultancy, collection and subsequent high temperature incineration of their hazardous wastes. At our facility near Heathrow Airport. We employ a variety of collectin vehicles operated by fully trained drivers and provide documentation to ensure compliance with all relevant legislation and guidelines.

Clinical Waste Division, Star Works, Star Lane, Knowl Hill RG10 9XY

www.hannahreed.co.uk Tel: 01223 882000 Fax: 01223 881888 Telford House, Fulbourn, Cambridge CB21 5HB

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Hannah-Reed cambridge@hannahreed.co.uk

Project Management consultants focussed on the design and procurement of research facilities. Working on behalf of the end user, we have acted on behalf of the majority of the major occupiers locally. Clients include Acambis, Amedis, Astex, Biofocus, CAT, CCD, Celltech, Cellzome, Domantis, Intercytex, Ionix, Lorantis, MedImmune, Medivir, Millennium, Paradigm, Peptide, Pfizer, PPD, Ribotargets, Vernalis and others. Also teaching and research facilities for the University of Cambridge and University of Nottingham. Total portfolio of developments exceeds 105,000sqm of new build and refurbishments. Services range from site selection and negotiation of agreements, with, and financial contributions from, landlords - through to design management and fit-out procurement. We have established an extensive database of design solutions, benchmark costs and development programmes and can give an early indication as to what can be achieved, at what cost and by when.

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Harley Street Cosmetic Ltd www.harleystreetcosmetic.com

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29 Harley Street, Research and Development Department, London W1G 9QR

We have our own successful range of natural herbal gels that have been successful selling for 10 years. We also develop formulations and testing for many pharmaceutical, biotech, cosmetic and spa companies/brands. Our expertise is in the development, testing and marketing of cosmetic products.

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Harpum Consulting

www.harpumconsulting.com

8 Kings Lane, Harrowden NN9 5BL

Tel: 01933 675079

Project management capability will be one of the deciding factors when looking at the successful biotechs of the future. Throughout industry those companies that have grasped project management and made it work for their industries are the ones that have been successful. Harpum consultants through their many years of experience within the life science sector and across industry can help you to understand your project environment. Through our database of academic research we know what best practice looks like and can help you to implement it. We work with your project organisation to identify the areas of need and develop bespoke solutions. Everyone at Harpum has one overriding concern – guaranteeing business benefit is created for you. Our ethos demands that in return for investing with us, you and your people gain high value returns staying with you until you are confident those outcomes, and business value, have been achieved.

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Harrison Clinical Research Ltd www.harrisonclinical.com Tel: 01353 668339

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Fax: 01353 661580 Gemini House, Bartholomew’s Walk, Cambridgeshire Business Park, Ely CB7 4EA

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Harten Group Ltd Dr Vernon Harten-Ash enquiries@hartengroup.co.uk www.hartengroup.co.uk Tel: 01223 233777 Harten Group, Explorer House, 7 Pioneer Court, Chivers Way, Histon, Cambridge CB24 9PT

www.hartsdirect.co.uk Tel: 01799 510128

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Harten Group is one of Europe’s leading providers of consultancy, interim management and executive search for the pharmaceutical and biotech industries. With over 2000 highly qualified specialists the company, which has been established for 15 years, delivers flexible resourcing solutions to meet specific needs - mostly in the UK but also in Europe. This bank of expertise can be harnessed in many different ways, from the recruitment of a single interim manager on a contract basis, finding a permanent employee through executive search for a ‘difficult to find role’ or fielding a team of consultants to address a more complex challenge.

Harts Office Supplies sharon@harts1836.co.uk

Harrison Clinical Research was founded in 1987 and is a privately owned full-service CRO with its headquarters in Munich, Germany. Regional offices are located in Austria, Belgium, France, Israel, Italy, Japan, Spain, Russia, the Ukraine, USA and UK. From these offices the clinical development needs of both Eastern and Western Europe as well as the USA can be achieved. In addition, HCR can offer a truly global approach to trials through its partnerships with like-minded companies in countries such as India, China, Japan and other Far Eastern locations. We can assist at every stage of the clinical development and registration of new pharmaceutical and biotechnology products and medical devices from Phase I through to Phase IV, from protocol design to final reporting, both locally and worldwide, including: - Study Design - Data Management Statistics - Phase I healthy volunteer studies - Analytical Services - Phase IIa POC/POP* patient studies - Medical Writing - Phase II III confirmatory studies - Independent Auditing - Project Management - Outsourcing - Study Monitoring - Training * POC/POP Proof of Concept/Proof of Principle As a mid-sized CRO, we pride ourselves in being able to provide a highly flexible and individualised service, which is supported with specialised knowledge and expertise, to assist the smaller and medium sized Device, Pharma and Biotech companies with early and late phase clinical development solutions. In our modern Clinical Unit (Munich) we specialise in performing Phase I first-in-man safety and tolerability studies (single dose and multi-dose) as well as pharmacokinetic, pharmacodynamic, drug-drug interaction, drug-food interaction and bioequivalence studies. We also specialise in performing studies in special patient populations (e.g. hypertension, hyperlipidemia, diabetics, rheumatoid arthritis, and elderly, etc.), as well as studies in renal impairment and hepatic impairment. Clearly, all CROs should complete every study to the highest quality standards. Indeed, Harrison Clinical Research has gone one step further for its clients. We are proud to be one of the first CROs worldwide to have been awarded the ISO 9001:2000 certification for ‘Design and evaluation of clinical trials for the pharmaceutical and device industries, including performance of Phase I trials and management and monitoring of Phase II/III/IV trials.

Fax: 01799 528082 Hart House, Shirehill Industrial Estate, Shire Hill, Saffron Walden CB11 3AQ

One Nucleus Directory 2011

Harts have been established since 1836 and is a leading UK independent dealer providing a ‘Single Source’ for all ERBI Members office requirements. We have built a reputation within ERBI over the last several years based upon competitive pricing, excellent, fast and professional customer service dedicated to ERBI members with a Local and National Distribution network in place, and a stock holding in excess of GBP5M of products, all available for next day delivery. Additional Value Added Services: *Shopping Service for daily consumable/catering/cleaning requirements normally purchased through a Cash Carry/Supermarket *’Try before you buy’ on a range of office Seating - no more costly uncomfortable purchases *Ergonomic Surveys - we have a range of ergonomic products for all requirements *Office Refurbishments/Project Management *Space Planning (CAD) - Help visualise final environment *Furniture Installations by our own dedicated Team *Leasing solutions - spread your costs *Used Toner Collections - Bins supplied *Print Audits - We can reduce your expenditure with our print solutions *Print Management - We can hold bulk stock for you in our secure storage area *On-site Design Print - All under one roof *Business gifts - any product can be sourced *Audio Visual Products and Installations *PAT Testing (Electrical) *PPE Equipment (Personal Protection Equipment) Benefits: *Service Level Agreement - ‘Guaranteed’ *Weekly and Monthly KPI’s monitored *Quarterly reviews *Competitive pricing for ERBI members *Solutions to help reduce expenditure *Stock replenishments (cupboards) *Single Sourcing of all non-core office products *Specials sourced *Dedicated single point of contact *Web enabled ordering system /Online catalogues *Next day delivery *No quibble collection of returns *Management information reporting *Invoices in required format *Credit procurement cards accepted *Environmental awareness and products to suit requirements ERBI Office Supplies Discount structure: *ERBI Core Contract Price List for office supplies - with up to 80% off RRP *Unique Contract Price List on your most commonly used office supplies items *Set discounts with up to 70% off RRP prices *Additional discounts off RRP on ‘Value for money ranges’:(5 Star) *Own brand Toners - 100% guaranteed - up to 10% additional page life - significant comparable savings.

Health Enterprise East Dr Anne Blackwood anne.blackwood@hee.org.uk www.hee.org.uk Tel: 01480 364925 Papworth Hospital, Papworth Everard, Cambridge CB23 3RE

A Health Enterprise East (HEE) is the NHS partner organization for Innovation in the East of England. HEE understands NHS clinical needs and how to overcome the operational and commissioning issues that hinder the assessment, purchase and use of new technologies within the NHS. HEE can help companies align their products and services to the needs of the NHS for win-win business solutions. HEE also provides access to products devised by NHS clinicians in response to identified unmet clinical needs which are available for in-licensing.

business@hpa.org.uk www.hpa.org.uk/business Tel: 01980 612221 Health Protection Agency, Porton Down, Salisbury SP4 0JG

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The UK’s Health Protection Agency provides solutions to infectious diseases and environmental hazards in partnership with industry, governments and universities.

With expertise in developing diagnostics, vaccines and other countermeasures, allied with our capabilities in process development, scale-up and GMP manufacture, the HPA is unique in being able to undertake translational research and turn ideas into new healthcare interventions and products.

By combining our experience in emergency preparedness and planning with specialist testing, research capabilities and internationally recognised EQA schemes the HPA is one of the world’s leading organisations dedicated to combating world wide health threats.

Tel: 01707 358627 Biopark, Broadwater Road, Welwyn Garden City AL7 3AX

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Heptares Therapeutics www.heptares.com

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Health Protection Agency Dr David Rhodes, Deputy Director Business Development

Heptares Therapeutics is a drug discovery company focused on identifying novel drug candidates targeting high-value, validated G-protein-coupled receptors (GPCRs) in multiple disease areas. The Company’s unique StaR™ technology enables Heptares to engineer and purify stable GPCRs to which it can apply contemporary drug discovery approaches, such as crystallisation and structure-based design, biophysical analysis of ligand interactions and fragment screening. This unique approach is expected to radically improve the chances of finding novel drug candidates (small molecules and biologicals) to previously intractable targets and will enable the development of safer and more selective therapeutic agents. Based on this integrated drug discovery capability, Heptares aims to progress promising candidates internally and through strategic alliances.

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HLBBshaw Dr Marc Wilkinson Senior Attorney marc.wilkinson@hlbbshaw.com www.hlbbshaw.com Tel: 01992 561756 Merlin House, Falconry Court, Baker’s Lane, Epping, Essex CM16 5DQ

HLBBshaw is a firm of European Patent & Trade Mark Attorneys established in 1989 with offices in Birmingham, Cambridge, Epping, Leeds and Reading. We incorporated in March 2006 to provide a modern business model and are now managed on corporate lines. Our professionals operate within six groups: Life Sciences, Pharma & Nutritional Sciences, Chemistry & Materials Science, Engineering, Electronics, Telecoms and Computer Science (ETC) and Trade Marks. HLBBshaw has an enviable success record of about 80% in contentious IP ranging from vaccines to packaging to neural networks. Further information about our professionals and HLBBshaw generally can be found on our website.

ceri@hma.co.uk www.hma.co.uk Tel: 01226 209450 HMA Digital Marketing, The Coach House, 51 Sackville Street, Barnsley, South Yorkshire S70 2BZ

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HMA Digital Marketing Dr Ceri Batchelder

HMA Digital Marketing is a leading brand and digital communications agency specialising in the life sciences. Dr Ceri Batchelder, HMA’s Business Development Director, is a life sciences & healthcare professional. Ceri has held business development roles at global medical devices firm Smith & Nephew PLC and at Manchester-based biotechnology company Epistem Ltd.

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Clients include 3M Healthcare, Kent Science Park, MEPC (owner of Granta Park), the University of Sheffield, the University of York and UK Trade & Investment.

Services include online brand strategy, website design and development, 3D animation, design and creativity, e-mail marketing, mobile phone applications, search engine optimisation (SEO) and social media.

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Hot To Trot Marketing Group www.hottotrotmarketing.co.uk

Tel: 01273 325523

Norwood House, 9 Dyke Road, Brighton BN1 3FE

Marketing and communications agency with broad experience in new business formation, launches, Mergers and Aquisitions, Venture Capital fundraising. We deliver all forms of marketing from strategic to social media and events.

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Immodulon Therapeutics

www.immodulon.com

69 Harley Street, London W1G 8QW

Tel: 0207 487 2787

Immodulon is interested in mycobacterial-based immunotherapies aimed at restoring appropriate immunoregulatory responses in conditions characterised by immune dysregulation. These products have potential in a wide range of indications and are expected to complement established and emerging clinical therapies. We are presently concentrating on developing immunotherapeutic options as adjunctive therapy for certain cancers with the aim of extending survival and enhancing quality of life. Through collaborations we are also supporting mycobacterial immunotherapy for the prevention and treatment of tuberculosis, following encouraging data from a recent Phase III trial in Tanzania.

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ImmuPharma www.immupharma.com Tel: 0207 152 4080

Fax: 0207 152 4001

50 Broadway, Westminster, London SW1H 0RG

ImmuPharma plc is a drug discovery and development group in London, U.K. with operations in its subsidiaries in Mulhouse, France and Basle, Switzerland. The company aims to develop novel drugs to treat serious medical conditions for which there is a high unmet need. It has five drugs in development to treat 1) Lupus, 2) Cancer, 3) Severe Pain, 4) highly resistant infections like MRSA and 5) Inflammatory and Allergic disorders . Each would represent a significant breakthrough in its field. The company also has a strong proprietary and collaborative drug development pipeline. ImmuPharma plc is publicly listed in London.

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Imperial College London www.imperial.ac.uk Tel: 0207 594 5880 Exhibition Road, London, SW7 2AZ

The Imperial Drug Discovery Centre was set up in January 2007 to address the growing gap between early stage academic research and commercial development by the pharmaceutical industry. Our strategy is that of a â&#x20AC;&#x153;virtual biotechâ&#x20AC;?, bringing the best expertise to the project in a timely manner. We are a small core of scientists that collaborate extensively both within the college and externally with industry and outsource blocks of work to contract research organizations . We work across therapeutic areas and have portfolio of projects ranging from target validation through to pre-clinical . http://www1.ic.ac.uk/medicine/research/institutes/drugdiscoverycentre/

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Imperial College London - Department of Immunology Chelsea & Westminster Hospital Campus, 369 Fulham Road, London SW10 9NH

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One Nucleus Directory 2011

Imperial College London - Toxicology Unit Tel: 0207 594807 E501 Burlington Danes Building, Hammersmith Campus, Ducane Road London W12 0NN

The Toxicology Unit is not a company, it is financed by the Health Protection Agency and works within an academic institution, Imperial College London.

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Imperial Consultants Dr Paul M. Cray consultants@imperial.ac.uk www.imperial.ac.uk Tel: 020 7594 6565 58 Prince’s Gate, Exhibition Road, London SW7 2PG

Imperial Consultants is the university consulting and knowledge transfer company of Imperial College London, Europe’s leading science university. The largest university knowledge transfer company in the UK, Imperial Consultants facilitates access by commercial, government and third sector organisations to the world-class researchers and facilitates at Imperial College in order to undertake complex consulting projects of all kinds. A particular focus for Imperial Consultants are projects across the entire spectrum of the life sciences including biodiversity, bioinformatics, biomedical materials, bionanotechnology, clinical medicine, drug discovery, ecology, genomics, medical imaging, proteomics, public health and synthetic biology.

www.infotogo.org.uk Tel: 01223 354097 Fax: 01223 847487 17 Priory Road, Cambridge CB5 8HT

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Info To Go Ltd info@infotogo.info

Info To Go Ltd is a Cambridge based information research and analysis service, working primarily for companies in the pharmaceutical, biotechnology, medical device and related industries. In effect, info to go acts as a virtual library for small to medium sized companies which do not have the need, or perhaps the budget for a full time in-house information specialist. info to go accesses scientific papers, news, technical and product literature, market reports by the section, patents, conference material, clinical trial details and deal and licensing information from some of the world’s most authoritative sources. By filtering out only the relevant information from a combination of these sources, info to go delivers timely, concise results without information overload.

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Institute of Biotechnology enq@biotech.cam.ac.uk www.biotech.cam.ac.uk/mbe Tel: 01223 334168 Fax: 01223 334162 University of Cambridge, Master’s in Bioscience Enterprise Programme, Tennis Court Road, Cambridge CB2 1QT

The MBE programme is an intensive, taught business course intended for those who have the ambition to found technology companies or take up leadership, executive or consultancy roles in the life science sector. Students are based at the University’s Institute of Biotechnology and have a close affiliation to Judge Business School. The nine month programme comprises a series of compulsory interdisciplinary modules that cover the commercial exploitation of the latest advances in biotechnology, together with the business and management skills associated with bringing scientific opportunities to market. Lectures and case studies are frequently delivered by senior company executives from the life science business sector. There is an opportunity to gain practical experience through consulting and internship projects, together with an international perspective of the industry sector during a study tour to Boston, USA. Attainment is continuously assessed and graduates are awarded the MPhil degree.

2nd Floor, Sir Richard Doll Building. 15 Cotswold Road, Belmont, Sutton SM2 5NG

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The Institute of Cancer Research www.icr.ac.uk

The Institute is a college of the University of London and works in partnership with The Royal Marsden NHS Foundation Trust. It employs approximately 1000 staff and students based in 3 sites in London and Sutton, Surrey.

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Insync Business Consulting www.insyncconsulting.co.uk

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Tel: 01794 341510 Fax: 01794 341510 Spearywell, Mottisfont, Romsey SO51 0LS

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Integrated Medicines Ltd

Dr Eddie Blair, Managing Director

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eddie.blair @integratedmedicines.co.uk www.integratedmedicines.co.uk Tel: 01954 718122

Integrated Medicines (IML) aims to introduce companion diagnostics into the drug development and commercialization pathways at appropriate time points. It does this by providing both services and products of interest to the healthcare sector including product value assessments, relationship brokering and tunable magnetic proteins (see integratedmagnetics.co.uk). Since inception in 2003, IML has worked with large and small companies, academics and applied research centres, as well as providing due diligence support to private investors and public sector organizations. Please visit our website to find out more, download information and join our newsletter mailing list.

Topfield House, Ermine Stree, Caxton, Cambridgeshire CB23 3PQ

IP Asset

www.ipasset.com

4th Floor, 33 Cavendish Square, London W1G 0PW

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IP Pragmatics Limited Elaine Eggington, Senior Business Development Manager info@ip-pragmatics.com www.ip-pragmatics.com Tel: 0203 176 0580

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Our successes include creating value through licensing, spin-out company creation and enhancing commercial service offerings for clients in the UK and overseas. Typical clients include companies both small and large, universities, research institutes and investors.

1 Quality Court, Chancery Lane, London WC2A 1HR

iRegulatory Ltd iRegulatory are a UK based European Regulatory Affairs consultancy. We provide regulatory advice for drug development, including input at early stages to advise on regulatory strategy. Other services include preparation for scientific advice meetings with regulatory authorities, clinical trial applications and regulatory writing. We have expertise in Quality, Biotechnology, Non-clinical and Clinical aspects of applications at all stages. We have a core team of experienced regulatory affairs consultants supported by the iRegulatory Panel, a group of external consultants with whom we have strong working relationships. The Panel combines the advantages of independent consultants (strength in specific areas of expertise) with the advantages of a regulatory team (depth and breadth). iRegulatory also have expertise and experience in paper and electronic publishing of all application types, including eCTD and NeeS, of clinical trial applications through to full MAAs.

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IP Pragmatics works with growing biotech companies and universities to create and realise value from their life science intellectual property, through provision of cost effective and commercially relevant business development, IP valuation and patent management services. We help our clients to identify, manage and create value from a broad range of intellectual property (IP) assets.

One Nucleus Directory 2011

Ithaka Life Sciences Ltd Paul Rodgers info@ithaka.co.uk www.ithaka.co.uk Tel: 01223 703146 St John’s Innovation Centre, Cowley Road, Cambridge CB4 0WS

Ithaka is a leading advisory and interim management business specialising in commercialisation of life science technologies. Our clients include companies, investors, public sector bodies, Universities and other research institutions. Our services include: • Technology, IP, commercial and market reviews, including due diligence; • Development and implementation of commercialisation strategies and business plans; • Start-up company creation and sourcing funding; • Provision of interim directors or senior management for growing companies. In addition to wide ranging business experience we have in-depth expertise in the following technology sectors: • Therapeutic proteins and antibodies • Biomarkers and diagnostics • Life science research tools • Regenerative medicine and medical devices • Drug discovery

Tel: 0121 4148777 Birmingham Research Park, Vincent Drive, Birmingham B15 2SQ

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IXC UK www.ixc-uk.com

IXC UK facilitates open innovation across sectors and industries providing ready access to pre-commercial, precompetitive and emerging technologies. IXC Intermediaries provide our core service provision: focused exposure to new technologies, methods and best practices: enabling the client to accelerate product development, access new markets, increase operational efficiency and improve revenue streams. Operating across disciplines and industries we interrogate a global network of people, knowledge and organisations to identify appropriate technical solutions for our clients. IXC UK, like its sister organisations IXC Australia and IXC Malaysia, is commercially neutral.

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JA Kemp & Co www.jakemp.com 14 South Square, Grays Inn, London WC1R 5JJ

J A Kemp & Co is a leading UK Patent and Trade Mark Attorney firm with a long-established reputation for high quality work. The Legal 500 described J A Kemp & Co as an ‘excellent’ firm with many world-class organisations amongst its patent and trade mark clients. Chambers & Partners identified the firm as ‘one of the more established and well respected players in the sector’, while Managing Intellectual Property commented that ‘J A Kemp & Co boasts one of the UK’s most highly qualified collections of attorneys’

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John Innes Centre jic.communications@ jic.bbsrc.ac.uk www.jic.bbsrc.ac.uk Tel: 01603 450902 Fax: 01603 450045

JIC has been designed and is managed as a centre for integrated bioscience. Its research approaches exploit cell biology, biochemistry, chemistry, genetics and molecular biology. Research on model organisms is carefully integrated with work on economically important species. JIC maintains an appropriate mix of fundamental, strategic and applied research that is continually being focused at the frontiers of discovery. JIC has over 30,000m sq of laboratory buildings, 8,000m sq of glasshouses and 187m sq of controlled environment growth rooms on a 50 acre site in Norwich. JIC leases these extensive facilities from the John Innes Foundation (JIC), a charity established from the will of our founder John Innes (1829-1904). JIC also has 400 acres of farmland for field trials.

Norwich Research Park, Colney Lane, Norwich NR4 7UH

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John Strafford

BioPark, Broadwater Road, Welwyn Garden City AL7 3AX

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Jon Jamin Designs jon@jonjamindesigns.co.uk

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www.jonjamindesigns.co.uk

We are a design company offering a personal, professional service in design prototyping over a wide range of engineering including the bio-tech and pharma industries. We can project manage and design from concept to prototype. Please see our website for more detailed information and examples of our work.

Tel: 01449 736707 Fax: 01449 736104 Barleydale, Cockfield Road, Felsham, Bury St Edmunds IP30 0QJ

Juice Resource Solutions

Maureen Park

www.juiceresourcesolutions.com

3 Soothouse Spring, St Albans, Hertfordshire AL3 6PF

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mpark@juicegroup.com

Tel: 01727 867772

A full service human resource business specialising in the life sciences sectors. We cover all functional areas in Healthcare, Medical Devices and Drug Development. Juice Interim Management Solutions: We provide experienced Interim Managers at short notice, for temporary assignments at specialist or senior level. All are hands on executives and managers with proven track records in their areas of expertise. Juice Permanent Recruitment Solutions: Our recruitment process is designed to take the pressure away from the managers and HR departments. We telephone interview all candidates and shortlist down to 3 or 4 specialists that match in skills, personality fit, salary expectation and location. We are extensively networked in the industry across the UK and Europe and use a mixture of database, advertising and head hunting recruitment to make sure that candidate and client are the right fit for each other.

Kelly Scientific Resources www.kellyscientific.co.uk Tel: 020 8481 1324

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Apple Market House, 17 Union Street, Kingston-Upon-Thames KT1 1RR

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Kilburn & Strode LLP www.kstrode.co.uk Tel: 0207 539 4200 20 Red Lion Street, London WC1R 4PJ

Kilburn & Strode LLP is a leading, top-tier London partnership of European Patent Attorneys, Chartered Patent Attorneys and Trade Mark Attorneys, dealing with all aspects of Intellectual Property, including patents, trade marks, domain names, design, copyright, passing-off and confidential information. The acquisition, enforcement and licensing of worldwide IP rights on behalf of our clients forms a core part of the business. It is consistently rated in the top tier in all independent surveys and the qualified patent and trade mark attorneys and litigators are made up of eighteen partners, seventeen associates and two consultants, each of whom specialise in dedicated fields of interest ranging from chemistry, through life sciences, engineering and IT & electronics.

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King’s Business, King’s College London Susan Foynes

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kingsbusiness-info@kcl.ac.uk www.kcl.ac.uk/innovation/ business Tel: 020 7848 6795 8th floor, Capital House, 42 Weston Street, London SE1 3QD

One Nucleus Directory 2011

King’s Business is a wholly owned subsidiary of King’s College London, responsible for driving innovation within one of the UK’s leading research universities. Our mission is to optimise the impact of research at King’s College London through the development of new opportunities and partnerships and to create value for the College in its externally-facing activities. The team supports the development of relationships with a broad range of external partners, including public sector, charities, cultural organisations, industry and SMEs across the whole range of our academic disciplines. This occurs via research collaborations, consultancy, executive education, the protection and licensing of IPR and the creation of new ventures.

Kings College London MRC Centre for Neurodegeneration Res

www.iop.kcl.ac.uk

De Crespigny Park, London SE5 8AF

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KISS Communications Simon Fryer simon@kisscom.co.uk www.kisscom.co.uk Tel: 0208 123 4575

KISS Communications is the integrated agency dedicated to keeping it simple. Our experienced team energise brands that aspire to be number one in their category, gain distribution and increase sales around the world.

We provide advertising, design, branding, digital, exhibitions and public relations services prepared against strategic plans with concise success measurement. The KISS guiding principles are to have a lack of unnecessary complexity in everything we do whilst delivering maximum effect with minimum means.

Church House, Kneesworth Street, Royston, Hertfordshire SG8 5AB

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KWS BioTest Ltd William Parish William.parish@kwsbiotest.co.uk www.kwsbiotest.co.uk Tel: 07900 240 692

KWS BioTest is an established contract research organisation that brings together internationally renowned scientific expertise in a commercially managed environment for the testing of prophylactic and therapeutic agents as treatments for human disease. We work closely with clients to to develop a truly bespoke and individual program. KWS BioTest offers a range of in vitro and in vivo preclinical services in the core areas of inflammation, infection, autoimmunity, allergy, CNS and pain.

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La Playa Limited Headquartered a short distance from Cambridge Science Park, and also with offices in London, La Playa provides expert, independent insurance and risk management advice for life science enterprises of all sizes. Our clients work in some of the most innovative, game-changing sectors in the UK, including drug/vaccine development, medical devices & healthcare sciences, bioinformatics, electronics and nanotechnology - so we know a thing or two about unconventional risk. And how to manage it. We offer FREE Enterprise Risk Planning for all ERBI members, helping start-ups to become investor-ready and helping more established firms to benchmark their insurance portfolios against current ‘best practice’. Advice & consultancy encompasses: • Asset Protection & cover for R&D activity • Intellectual Property • Professional Negligence • Clinical Trials Liability • Crisis Management & Disaster Recovery

• Consequential Losses • Employers’, Public & Product Liability • Directors & Officers Liability • Environmental Liability • Product Contamination & Recall

Fax: 01442 874354 London Associates, 105 High Street, Berkhamsted HP4 2DG

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LA-Design Tel: 01442 862631

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KWS BioTest Ltd, School of Medical Sciences, University Walk, Bristol BS8 1TD United Kingdom

www.La-design.co.uk

LA is a well-established Product Design and Development Consultancy, structured for brand-led companies with serious products to deliver. Experts in medical & scientific equipment, LA have clients in the US, Europe, Africa and the Far East. LA differentiated from its competition by implementing a system where a partner always takes both client and project responsibility with project teams structured to provide the optimum mix of skills and experience for specific project needs. These methods have resulted in five International Design Effectiveness Awards for products commercially proven to have had a major impact on company profitability and market share. Recent DBA ‘league tables’ ranked LA as one of the best Product Design Companies in the UK

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Labute Limited Dave Jones

Founded in 1978 Labute is Cambridge’s oldest commercial printing company.

dave@labute.co.uk

Incorporating a wide range of both modern and traditional printing technologies our aim is to help our customers achieve their marketing objectives by communicating with whichever printing discipline is most effective.

www. labute.co.uk Tel: 01223 424444 Cambridge Printing Park, Milton, Cambridge CB24 6AZ

Law for Life Science Suzanne V. McLean smclean@lawforlifescience.com www.lawforlifescience.com Tel: 0207 736 0833 17 Elthiron Road, London SW6 4BN

Law for Life Science provides flexible legal services to emerging and established life science companies that need pragmatic, commercial legal advice from lawyers who have worked in the industry. We have over 20 years experience working with many different types of lifescience companies in UK, Europe and the US. We hit the ground running, understand tight timescales and tight budgets. Law for Life Science provides a cost effective way to obtain professional knowledgeable industry expertise.

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LE Executive Resourcing Ltd

LE Executive Resourcing provides Talent Management solutions tailored to your specific requirements. Specializing in finding people for senior management roles and Board positions, we have successfully completed a wide range of assignments for companies ranging from start-up Biotechs to global industry leaders. Regardless of the size of your business, we recognize the importance of your project, and value each client equally. You will receive a dedicated bespoke service, the chief goal being to ensure that the appointment will make a measurable difference to your organization. We have an unsurpassed track record in recruiting for all functions and disciplines including: Business Development Discovery Research Finance Human Resources Manufacturing Marketing Operations Product Development Quality Regulatory Affairs We look forward to helping you.

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Leads to Development Dr Jonathan Kearsey jkearsey@leadsto development.com www.leadstodevelopment.com Tel: 0207 183 6415 London BioScience Innovation Centre, 2 Royal College Street, London NW1 0NH

Tel: 020 8943 7000 Queens Road, Teddington TW11 0LY

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Our services allow our clients to reach clinical milestones rapidly and cost effectively, without building headcount and infrastructure. We assess project potential, design development strategies and deliver effective project advancement in order to minimise risk and increase project value. Our experience of the biotechnology sector also allows us to offer a range of business services and strategic advice (including due diligence) to investors and drug developers.

LGC Genomics www.lgc.co.uk

LEADS TO DEVELOPMENT (L2D) manages the development of its clients’ novel therapeutics, from in vivo proof of concept through to phase I clinical trials, using scientific, project management and business expertise.

One Nucleus Directory 2011

LGC is an international leader in the laboratory services, measurement standards, reference materials and proficiency testing marketplaces. Our business is focused upon customers in: forensic science; pharmaceutical and biotechnology research, development and quality control; food chain and environmental surveillance and safety; life science, genomics, proteomics and basic research. LGC is the UK’s designated National Measurement Institute for chemical and biochemical analysis , the National Reference Laboratory for a range of key areas, and is also the host organisation for the UK’s Government Chemist function.

LGC Ltd

www.lgc.co.uk

Queens Road, Teddington TW11 0LY

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Link China Solutions Ltd info@chinapharma.co.uk www.chinapharma.co.uk Tel: 01223 598070 Fax: 01223 598001

LCPS support UK small, medium and large biotech and pharmaceutical companies to build the collaboration with Chinese partners and provide a full suite of services across each phase of the outsourcing lifecycle from strategy alignment, partnership selection, collaborative partnering, outsourcing transaction in drug discovery and development, clinical trial, contract manufacturing, to China market entry and development. Our clients can minimize the cost; gain the competitive advantage in the global market and access one of the world largest pharmaceutical market-China.

1010 Cambourne Business Park, Cambourne CB23 6DP

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Lipoxen

www.lipoxen.com Tel: 0207 691 3584

2 Royal College Street, London NW1 0NH

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London BioScience Innovation Centre www.lbic.com Tel: 0207 691 2069 Fax: 0207 419 5983 2 Royal College Street, London NW1 0NH

The London BioScience Innovation Centre (LBIC) provides a focus for life sciences activity in the UK capital, offering laboratory and office facilities of an exceptionally high standard and a professional front door that cannot fail to impress. Owned by the prestigious Royal Veterinary College, LBIC is home to over 30 biotechnology and life science companies in central London, including small start-ups and more established players. We attract biotechnology, life science product and diagnostic companies, contract research organisations, medical device companies and service providers. LBIC clients benefit from shared networking space and meeting rooms as well as close proximity to the various financial services available throughout the Capital. Our management team is experienced in building and supporting biotechnology businesses. We understand both the pitfalls and the drivers for success.

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London Genetics Dominique Kleyn dkleyn@londongenetics.com www.londongenetics.com Tel: 020 7594 1838

London Genetics provides consultancy services to pharmaceutical, biotech and other life science organisations on the use of genetics and biomarkers in drug and diagnostic development. We sit at the interface of industry and academia, helping the research community to harness commercial benefit from their research and resources. Industry comes to us with their key clinical development questions, we advise on the design of clinical studies and analysis of results, and our members contribute samples and patient cohorts along with their expertise in biomarker selection, data gathering and storage and further analysis.

Imperial BioIncubator, Prince Consort Road, London SW7 2BP

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Lumora Ltd www.lumora.co.uk

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Tel: 01353 646285 Fax: 01353 646282 Denmark House, Cambridgeshire Business Park, Angel Drove, Ely CB7 4ET

Management Forum

Sarah Packham

98-100 Maybury Road, Woking GU 21 5JL

www.management-forum.co.uk

Management Forum uses its skills, expertise, links with regulatory bodies and industry-wide speaker network to deliver enlightening events and training programs. Management Forum is a state-of-the-art training provider offering: • Face to face events • In-house training • Online packages • Event Management For professionals from five key industries: • Pharmaceutical/Biotech • Medical Devices • Intellectual Property • Legal • Animal Health For further information please visit: www.management-forum.co.uk

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Managing Resources Ltd info@managingresources.com www.managingresources.com

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Tel: 01223 566158 Fax: 01223 566159

Many of our present and future clients are based in countries like USA, Canada, Australia and New Zealand. They recognise the European potential for their products; they require our help in understanding the market opportunity, appreciating the varied healthcare structures in different countries, determining the best entry strategy and finding the right partners, possibly including M&A. We provide support in regulatory affairs, finding finance, addressing legal issues and recruiting permanent staff recommending specialists that we work with regularly.

18 Topcliffe Way, Cambridge CB1 8SH

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Marks and Clerk Tim Andrews

TAndrews@marks-clerk.com

Tel: 01223 345520

www.marks-clerk.com

62-68 Hills Road, Cambridge CB2 1LA

Marks & Clerk is one of the most highly regarded intellectual property firms in the UK. Our patent and trade mark attorneys and solicitors offer clients single point access to a comprehensive range of IP services across a full range of sectors - with notable experience in life sciences. Services include strategic IP and practical advice on patent and brand protection and portfolio management, licensing, enforcement, due diligence and litigation. Working closely with clients to understand their specific business requirements, we produce commercially effective work at a competitive price. We have a network of offices in the UK (11 locations), in Europe, Asia and North America providing clients with an integrated local and global service.

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Mathys & Squire LLP Martin MacLean

mrmaclean@mathys-squire.com www.mathys-squire.com

Tel: 0207 783 00000

120 Holborn, London EC1N 2SQ

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Mathys & Squire has over 100 years of experience in providing Intellectual Property services to UK industry. Our attorneys work across a number of technical disciplines, including biotechnology, pharmacology, healthcare & medical devices, and chemistry. We have a global track record in securing valuable Intellectual Property rights for universities, government, start-ups and spin-out companies. Our attorneys also specialize in freedom-to-operate and due diligence activities, and we are particularly proud of our extremely high success rate in both defending and challenging patents before the European Patent Office. Most importantly, we develop IP strategies that align with our clients’ commercial plans.

Maxwell Safety & Health Ltd Chris Maxwell info@maxwellsafety.com www.maxwellsafety.com Tel: 0845 519 2760 St John’s Innovation Centre, Cowley Road, Cambridge CB4 0WS

Maxwell Safety was formed in 2005 with the aim of providing practical, cost effective health and safety solutions for small and medium enterprises. We have particular expertise within the biotechnology, pharmaceutical and ‘hitechnology’ sectors. The company has very close links with One Nucleas providing health and safety training for its members, including Biological Safety Officer and Laboratory Safety training. Our H&S consultants are Chartered Health and Safety Practitioners, with extensive experience in delivering pragmatic health and safety solutions and dynamic training. We are committed to supporting managers responsible for health and safety to comply with legislation and to adopt a sensible approach to health and safety that is a benefit to the business, not a hindrance.

licensing_europe@merck.com jacqueline_canham@merck.com www.merck.com/licensing Tel: 01992 452840 Hertford Road, Hoddesdon, Hertfordshire EN11 9BU

E F Merck Sharp & Dohme Limited (MSD) is the European subsidiary of Merck & Co., Inc., of Whitehouse Station, New Jersey, USA, a leading research-based pharmaceutical company that discovers, develops, manufactures and markets a wide range of innovative pharmaceutical products to improve human health.

Today’s MSD is a global healthcare leader who is working to help the world be well. Through our medicines, vaccines, biologic therapies, and consumer and animal products, we collaborate with human and animal health professionals across the UK and in more than 140 countries to deliver innovative health solutions.

A comprehensive list of our interests is available at www.merck.com/licensing and includes: atherosclerosis and cardiovascular disease, stroke, diabetes and obesity, asthma and COPD, pain, oncology, antibiotics, antifungals, antivirals (HCV and HIV), novel vaccines, Alzheimer’s disease, neurodegeneration, schizophrenia, ophthalmology, osteoporosis, and women’s health. For Phase III-ready candidates and beyond, Merck is interested in any therapeutic area. We are also seeking to integrate key product enablers (e.g., biomarkers, diagnostics, devices, and information) into the development of our products.

Newnham House, Cambridge Business Park, Cambridge CB4 0WZ

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Mewburn Ellis LLP www.mewburn.com

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Merck & Co Inc Licensing & External Research Europe

Mewburn Ellis LLP has one of the largest groups of patent attorneys specialising in biotechnology and life sciences in Europe. Our proactive approach and expertise reflect the high level work we do for a wide range of clients, from world renowned biotech companies based in the US and Europe, acting either directly or through their outside counsel, to small and medium sized companies, universities, charities, and funding bodies. We handle a substantial number of oppositions and appeals at the European patent office and have considerable expertise in drafting and prosecuting patent applications, due diligence work, infringement opinions, portfolio management and strategic patent advice.

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Micron Research The Micron Group is a contract clinical research company offering global services (consulting, clinical trials [Phase I-IV], communications data management) with offices in the UK, USA S. Africa. The Micron Group has four Core Business Units: 1) Consultancy - Strategic advice planning project management from discovery to market support. 2) Clinical Research - Clinical trial (Phase I-IV) planning, organisation, management and monitoring - Electronic data capture (EDC) analysis 3) Communications - Integrated strategic planning - Medical writing (papers, posters, slide kits) - Regulatory submissions - Symposium meeting organisation - Key opinion leader development - Advisory boards 4) Data Management Technologies - Standard (SAS) innovative (SILK) technologies - EDC - Graphic design Website design hosting

Midven Limited www.midven.co.uk Cavendish House, 39-41 Waterloo Street, Birmingham B2 5PP

Midven is an owner managed, entrepreneurial, venture capital company located in the heart of Birmingham. We have been successfully investing in dynamic, small and medium sized businesses since we started in 1990 when six Midlands based entrepreneurs established the business. Like many of the companies we invest in, we completed a management buy-out in October 2007, when the investment team acquired the business from the original founders. This personal investment by the members of the team reflects our confidence in the future of Midven as well as the companies we have invested in. We have ambitious plans and are targeting new funds focused on the early stage, technology and SME markets, capitalising on the expertise we have gained in these areas over the last 18 years.

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Millipore (UK) Ltd www.millipore.com

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232 Ugg Mere Court Road, Huntingdon PE26 2RJ

Millipore carries out cell and biochemical assay services across primary screening, hit to lead, lead optimisation, profiling and into preclinical. Key strengths include a large range of functional cell-based assays for GPCRs and ion channels, and the broadest commercial panel of kinase and phosphatases. Millipore also specializes in the analysis of biological therapeutics. Providing services for biomarkers, toxicokinetic / pharmacokinetic analysis, immunophenotyping, immunogenicity (ADA) and potency testing.

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Mills and Reeve LLP

www.mills-reeve.com

Fax: 01223 324549

Tel: 08706 000011

Francis House, 112 Hills Road, Cambridge CB2 1PH

Mills Reeve is one of the UK’s leading healthcare law firms and advises government, health and academic institutions on IP and related issues such as licensing, MTAs, supply of human tissue, stem cells, clinical trials and medical devices. We have extensive experience in the EU, USA, China and other countries, which allows us to help you achieve your global aspirations. We can help you with the concerns you may face with outsourcing agreements and collaborations, manufacturing and distribution. Our life sciences group is a full service practice and with top ranking lawyers in corporate finance and funding we can support your company from seed to listing and beyond. Our clients include leading biotech companies, investors, key NHS organisations, and world-class universities. Recent work has concerned new tissue legislation, patent licences and litigation, major research collaborations, clinical trials, international stem cell and blood supplies and the supply of pandemic vaccines.

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Mintz Levin Cohn Ferris Glovsky and Popeo LLP Ms Susan Foster

Mintz Levin is a full-service law firm with 450 lawyers in the UK and US.

sfoster@mintz.com

Working with biotech, pharmaceutical, and medical device manufacturers - and their investors and underwriters - our Life Sciences practice is one of the largest in the world. We also work extensively with academic and medical institutions, hospitals and physicians, and other health care clients. Because our UK and US offices work seamlessly together, we have a unique ability to advise clients on their trans-Atlantic and international operations.

www.mintz.com Tel: 020 7776 7300 Alder Castle, 10 Noble Street, London EC2V 7JX

Our clients include emerging companies as well as established privately-held and publicly-listed companies. With practice strengths in areas such as intellectual property, company formation and governance, and venture capital and financing as well as deep industry experience in life sciences, health care, energy, clean technology, and information technology, we serve as a springboard for many UK firms entering the US market and expanding internationally.

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Miranda Weston-Smith Consulting Miranda Weston-Smith

Miranda@mws-consulting.co.uk

Tel: 01223 511664

www.mws-consulting.co.uk

St John’s Innovation Centre, Cowley Rd, Cambridge CB4 0WS

Miranda Weston-Smith advises entrepreneurs, companies and universities on business development in healthcare and biotech. She is experienced in intellectual property negotiations, business planning and fund-raising. Starting a Technology Company, the book Miranda wrote while at Cambridge Enterprise, University of Cambridge is available at enquiries@enterprise.cam.ac.uk. Partner organisations include 4D Biomedical, Cambridge Healthcare and Biotech, Centre for Entrepreneurial Learning and St John’s Innovation Centre. Miranda is a graduate in Natural Sciences, University of Cambridge, holds the AAT Diploma in Accounting, and a Fellow of the Linnaean Society.

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Mitsubishi Pharma Europe Ltd David Brocklebank

www.mitsubishi-pharma.eu Tel: 0207 065 5002

Fax: 0207 065 5002

Dashwood House, 69 Old Broad Street, London EC2M 1QS

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Mitsubishi Pharma Europe is the European Headquarters of one of Japan’s largest pharmaceutical companies, Mitsubishi Tanabe Pharma Corporation. Based in London, Mitsubishi Pharma Europe is engaged in the clinical development of new drugs for the European markets. Mitsubishi Pharma Europe is conducting trials in Europe in the following therapy areas; cardiovascular, diabetes, CNS and renal conditions. The staff include regulatory, QA, clinical, biostatistics, medical information, pharmacovigilance, pharmaceutical technology and marketing.

Modern Biosciences plc www.modernbiosciences.com 24 Cornhill, London EC3V 3ND

Modern Biosciences is a drug development company that sources late-stage discovery projects from academia and spin-out companies, conducts early proof-of-principle clinical studies and subsequently out-licenses the resulting programs to the pharmaceutical and biotechnology industries.

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Morrison & Foerster (UK) LLP info@mofo.com www.mofo.com Tel: 0207 9204025 Fax: 0207 4968500 7th Floor CityPoint, One Ropemaker Street, London EC2Y 9AW

Morrison & Foerster provides a full-range of legal services to clients in the biotechnology, medical device, pharmaceutical and healthcare industries. The firm’s Life Sciences Group work with life sciences companies at every phase of their growth cycle, including formation and financing of early-stage ventures; start-up technology transfer; structuring and negotiating licenses, R&D collaborations; planning and developing IP portfolios; M&A; IPOs and follow-on securities offerings; protecting and defending IP rights; and developing and financing new research and manufacturing facilities. We are uniquely positioned to serve the global life sciences industry with over 130 lawyers in the U.S., Asia and Europe. Our European life sciences practice offers unrivalled transactional expertise. Led by Julian Thurston, one of Europe’s top commercial life sciences attorneys, Paul Claydon and James Gubbins, two of Europe’s top corporate life sciences attorneys, we provide advice on the full-range of issues relevant to Life Science Companies, their investors and their Investment Bank Advisers.

The MRC’s mission is to improve human health through world class medical research.

techtran@mrc-centre.cam.ac.uk

It invests around £70 million annually in the 7 Cambridge based MRC research establishments including the Laboratory of Molecular Biology, a world-class institute for understanding biological processes at the molecular level, applying novel methodology and generating underpinning science for human health advances. Other MRC units in the Cambridge region specialise in a variety of key areas including cognition and brain sciences, human nutrition, cancer, epidemiology, biostatistics and mitochondrial biology. The MRC’s expertise in these important areas offers great opportunity for fruitful interactions with industry and academia alike.

MRC Centre, Hills Road, Cambridge CB2 0QH United Kingdom

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Megan Davies

Tel: 01223 248011

MRC Centre

www.mrc.ac.uk

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MS Therapeutics Limited www.mstherapeutics.com Beechey House, 87 Church Street, Crowthorne RG45 7AW

MS Therapeutics Limited is a Speciality Pharmaceutical company focussed on the development of new medicines for multiple sclerosis and related disorders.

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Mundipharma International Ltd www.mundipharma.co.uk Tel: 01223 426626 194 Cambridge Science Park, Milton Road, Cambirdge CB4 OAB

The Purdue/Mundipharma/Napp independent associated companies are world leaders in the development and marketing of proprietary analgesics for the treatment of moderate to severe pain, with products such as Targin, BuTrans, Norspan, OxyContin and Palladone. A growing franchise in novel oncology therapies comprises the marketed products DepoCyte and Ribomustin, and Fodosine, which is currently in clinical development. Mundipharma has the European rights to FlutiForm and is conducting Phase III clinical trials as an entry strategy into the respiratory market. Product sales are made in over 100 countries worldwide, supported by a worldwide sales and marketing operation that comprises over 1 000 field sales representatives in Europe. The companies are committed to building their presence in the areas of analgesia, oncology and respiratory medicine. In-licensing is a key component of the companies’ portfolio building strategy. Substantial medical research and regulatory affairs functions are located in the UK (Cambridge) and Germany, with expertise in handling European clinical research and worldwide product registrations.

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National Skills Academy Process Industries www.process.nsacademy.co.uk

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Tel: 01325 740900 Fax: 01325 740901 5 Pioneer Court, Morton Palms Business Park, Darlington DL1 4WD

The National Skills Academy Process Industries is an employer-led centre of excellence launched to address skills and training needs throughout the chemical, polymer, pharmaceutical manufacturing sectors. The Skills Academy aims to create a highly skilled workforce capable of competing on a global stage as well as promoting the Process Industries as a progressive and exciting career choice. Its main aim is to encourage employers to engage in frontline staff training so that their current workforce can achieve accredited qualifications to an industrywide Gold Standard. The Skills Academy works alongside training providers and educational bodies to ensure that more people enter the industry equipped with the skills the industry needs. The Skills Academy has extensive commitment from Process Industries employers to support its inception and its aims—through this involvement, companies can play a key role in helping create the high performing workforce of tomorrow.

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Nature Publishing Group

Samantha Savalio

www.nature.com

The Macmillan Building, 4 Crinan Street, London N1 9XW United Kingdom

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s.savalio@nature.com

Tel: 020 7833 4000

NBS Biologicals Ltd Chris DeStefano chris@nbsbio.co.uk

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Nature Publishing Group (NPG) brings leading scientific and medical research to your desk top. The NPG portfolio combines the continued excellence of Nature, its associated research and review journals, and over 50 leading academic and society journals in the life, physical and clinical sciences. Open access options are offered through both the academic and society journal as well as through a new multidisciplinary journal: Nature Communications. NPG also provides news content through Nature News and scientific career information through Naturejobs. For more details about our products and services and sponsorship and advertising opportunities please visit our website.

NBS Biologicals Ltd is a supplier of molecular biology reagents, kits and chemicals to the research industry. In addition to representing several major international brands in the UK we have also introduced our own ‘NBS’ range of electorphoresis products and are able to source reagents and chemicals in research and bulk quantities.

www.nbsbio.co.uk Tel: 01480 433875 14 Tower Square, Huntingdon, Cambridgeshire PE29 7DT

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New England Biolabs (UK) Ltd Ed Bagenal

info@uk.neb.com

75/77 Knowl Piece, Wilbury Way, Hitchin SG4 0TY

www.neb.uk.com

Both NEB and CST produce reagents for drug discovery, basic research and scale up in cellular and molecular biology, including custom and bulk preps. NEB’s interests include enzymes used at the DNA, RNA and protein levels. These extend from PCR and Next-gen sequencing to protein expression and analysis. CST’s interests cover cell signalling and including phospho-analysis/profiling. CST produces antibodies that are screened and validated for particular applications (HCS, Flow, IHC etc). CST has novel antibody generating technologies. For more information on CST products and services, please email info@uk.neb.com

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NHS Innovations London Ltd www.nhsinnovationslondon.com

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Tel: 0207 380 1701 6th Floor, West Wing, 250 Euston Road, London NW1 2PQ

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NHS Innovations London (Ltd) aims to aid the financial health of London NHS Trusts, the physical and emotional health of patients and the economic development of London and the UK. We work with London NHS Trusts to identify promising innovations, provide a swift, objective analysis of their commercial potential, secure appropriate intellectual property protection and support inventors and their teams to fast track ideas to market. Through the endeavours of NHSIL, patients and NHS Trusts benefit from new and enhanced therapies, diagnostics, medical devices, equipment, software and health education products. Inventors gain appropriate recognition and reward for their ideas and revenue derived from their inventions can be reinvested into the NHS to promote better healthcare for the future.

Norwich Research Park Dr Matthew Hills matthew.hills@nrp.org.uk www.nrp.org.uk Tel: 01603 450925 The Norwich BioIncubator, Norwich Research Park, Colney Lane, Norwich NR4 7UH

The Norwich Research Park is a community of innovative businesses and research scientists with over 11,000 staff based at the University of East Anglia, four life science research institutes and a teaching hospital. The Park has 60,000 sq ft of commercial laboratory and office space in its NRP Innovation Centre and Norwich BioIncubator. Land is available for new-build to suit. Enquiries to the NRP office are welcomed. The NRP has a great deal of biotech, biomedical and clinical expertise and facilities that can be accessed via the NRP office (see website). The NRP office promotes the research capabilities and expertise of the partner organisations and fosters business development on the Park.

c/o Biological Sciences, University of Warwick, Gibbet Hill Road, Coventry CV4 7AL

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Novolytics Limited www.novolytics.co.uk

Novolytics was formed in 2002 as a spin-out from the University of Warwick, Coventry, UK, to exploit the results of research into the use of bacteriophages to combat bacterial infection (phage therapy). The unique proprietary technology of the company is the basis for its success and its market readiness.

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Novus Environmental Novus Environmental is a fully licenced waste management company providing high quality, value-for-money solutions for the collection and disposal of your wastes. Our service is based on strong ethics, the professionalism of our staff and the speed of our response. Your organisation, like many others, has a legal requirement to dispose the waste it produces in a compliant manner. Whether you are from the commercial, or public sector, to have this responsibility managed quickly, efficiently and legally is of paramount importance and convenience. The company has established itself as one of the leading experts in the disposal of a multitude of wastes including: clinical, sharps, medicines, human, animal, food, seized goods, electrical equipment and confidential. Working with novus environmental gives clientâ&#x20AC;&#x2122;s piece of mind by ensuring compliance with current legislation, protecting an organisationâ&#x20AC;&#x2122;s reputation and providing certification documenting waste movement right through to destruction.

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O2h Sunil Shah sunil@o2h.com www.o2h.com Tel: 01223 437014

O2h is a privately owned, medicinal chemistry service company founded in 2003. The group has two sites, a project management office in Cambridge, UK and its operations in Ahmedabad India. Our Indian base allows us to provide incredible speed/value compared to companies with operations in the West. O2h has developed a 10,000 sq m research facility, this has capacity for 28 dedicated 12 FH lab units. Aside from our core chemistry strengths, O2h have also been enhancing its in-house ADME capability. Together with the new state-of-the-art campus and ADME facilities, O2h is geared towards providing teir1 services for managed discovery research.

23 Cambridge Science Park CB4 0EY United Kingdom

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Office Team Rod Weedon rod.weedon@officeteam.co.uk www.officeteam.co.uk

OfficeTeam are the leading independent Office Services and Supplies Company in the UK. Uniquely structured to provide a local next day service nationally.Specialist areas: Office Supplies, Furniture, Print and Print Management, File Data and Storage, Digital Dictation & Transcription, Document Production, Workware, Computer Consumables, Copier and Printer Supply and Maintenance.

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Tel: 01284 767711 Mob: 07967 348150

29 Eastern Way, Bury St Edmunds, Suffolk IP32 7AB

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OncoLytika Ltd www.oncolytika.com

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Tel: 07812 046749

Oncolytika is an integrated theranostics company developing diagnostics, imaging agents and therapeutics in the oncology area

Fax: 0560 1078911 1 The Firs, Wilburton, Ely CB6 3FL

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Orion Automation Ltd

Keith Reeds

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keithreeds @orionautomation.co.uk www.orionautomation.co.uk Tel: 01480 891801 Orion Automation Ltd, 2 High Street, Alconbury Weston, Huntingdon, Cambridgeshire PE28 4JP

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Using leading edge hardware and software products we offer custom built, precision, high speed inspection systems using 2D and 3D technologies, where accuracy, reliability and repeatability are paramount. Our customers are in many diverse areas including pharmaceutical, medical, biotech, nuclear, automotive, electronics, printing and packaging, food, agriculture and general manufacturing. Typical uses include checking, measuring, counting, classifying and recording. We are also able to include any mechanical handling, electrical and control requirements to form a total turnkey solution if required.

Osborne Clarke Dr Janita Good janita.good@osborneclarke.com

Orion Automation provides high performance, intelligent, automated vision systems for use in laboratory, R&D and manufacturing applications.

www.osborneclarke.com Tel: 0118 9252146 Apex Plaza, Forbury Road, Reading, Berkshire RG1 1AX

Osborne Clarke is a leading European law firm providing business-focused solutions that take full account of the commercial drivers and current trends in the market practice. We have strength in depth and breadth. Osborne Clarke boasts a headcount of around 600 staff across Europe We have a strategic focus on key sectors. As a firm, we focus on the chosen sectors of our client base. For example, digital business, lifesciences & healthcare are key sectors for us. We are top ranked in legal directories. For instance we are ranked highly for mid-market M&A, venture capital, intellectual property, commercial and competition.

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PA Consulting Group www.paconsulting.com

Tel: 01763 261222 Fax: 01763 262862

Cambridge Technology Centre, Back Lane, Melbourn SG8 6DP

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Page White and Farrer www.pagewhite.com

Tel: 0207 8317929 Fax: 0207 8318040

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Bedford House, John Street, London WC1N 2BF

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With each of our practitioners focussing on particular technologies or legal disciplines, we can provide you with a winning combination of technical knowledge, business acumen and a sound appreciation of the workings of the law. IP has become a global issue as national boundaries are transcended by new technology, so an international approach is now vital. We have expertise in handling IP in all countries, and we maintain a strong working relationship with highly respected firms throughout the world. Our biosciences practice serves all areas of biotechnology including drug discovery and delivery, molecular biology, immunology, diagnostics and bioinformatics. We represent clients before the UK and European Patent. Our patent services include the following: - drafting, filing and prosecution of patent applications - defending clientsâ&#x20AC;&#x2122; European patents against opposition - drafting and filing oppositions to third party European patents - applications for supplementary protection certificates - opinions on infringement and validity of third party patents - surveillance of third party patent activity assistance in due diligence process - assistance in litigation.

PAION UK Limited www.paion.com Compass House, Vision Park, Chivers Way, Histon CB4 9ZR

A PAION UK Ltd (formerly CeNeS Pharmaceuticals) is a subsidiary of PAION AG, a biopharmaceutical company headquartered in Aachen, Germany. PAION is specializing in developing and commercializing innovative drugs for the hospital-based treatment of central nervous system (CNS) disorders and thrombotic/cardiovascular diseases, indications for which there is a substantial unmet medical need. The company intends to further expand its portfolio of drugs by exploiting its core expertise in identifying high-potential compounds, licensing or otherwise acquiring them and advancing them through the clinical development and regulatory approval process. PAION is listed at the Frankfurt Stock Exchange (Prime Standard Regulated Market, Stock Symbol PA8, ISIN DE000A0B65S3).

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PALL Life Sciences www.pall.com Tel: 02392 303358 Walton Road, Portsmouth PO6 1TD

The life sciences industry is both driven and united by its need for speed to market, product reliability and economics. Pall’s leading edge filtration, separation and purification technologies and services play an essential and pivotal role in this industry’s ability to achieve these goals. In the laboratory, Pall products help to facilitate the drug discovery and development process to get innovative drugs to the market faster. In Biopharmaceuticals, Pall filtration, chromatography, sampling, monitoring and quality assurance products, together with technical services in validation, assays and process optimization are applicable to laboratory and pilot-scale development, aseptic processing, biologicals, bioprocessing, fermentation and downstream processing.

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PASS Tel: 01379 672379

Wooley Road, Alconbury, Huntingdon PE28 4HS

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Peakdale Molecular Ltd enquiries@peakdale.com www.peakdale.com Tel: 01298 816771 Fax: 01298 816701 Peakdale Science Park, Sheffield Road, Chapel-en-le-Frith, High Peak SK23 0PG

Peakdale Molecular offers a class-leading range of products and services to its pharmaceutical and biotechnology customers to accelerate their drug discovery initiatives. At its very core, Peakdale’s approach is based upon its long & successful track record of problem-solving within our customers’ discovery projects. We are renowned for completing difficult synthetic organic and medicinal chemistry against time & cost constraints for customers big and small the world over. This we do through a huge variety of FTE or Fee-for-Service models designed individually to suit customer requirements. Whether it is a process development project, a small molecule discovery programme that needs computational, chemistry & ADME services or “design & make” projects for cores, scaffolds, back-up lead series, Peakdale offers flexible, creative and confidential support for your discovery project. Put our experience to the test.

heather.whitaker @people-strategies.net www.people-strategies.net Tel: 07949 349 925 8 Home Farm Court, Shantock Hall Lane, Bovingdon, Hertfordshire HP3 0NQ

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People Strategies Ltd Heather Whitaker

HR consultant and senior HR interim provider who established People Strategies in 2005 following a successful career in blue chip companies. Previous accountabilities in Sales and R&D (globally), Corporate HQ (pan European) and manufacturing (UK). Looks for large and small assignments, including • HR Transformation - HR strategy, accountability design, upskilling of BPs • M&As - due diligence, TUPE and benefits costings and transfers • Performance management and reward systems - systems implementation • Organisation change - site relocation, closures, re-structuring

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Permedx Consulting Ltd www.permedx.co.uk

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Baillie Court, Dunbar EH42 1SS Scotland

Permedx Ltd is a life science consultancy devoted to increasing R&D efficiency and Return of Investment in both pharmaceutical and biotechnology firms by the integration of personalised and translational medicine strategies. We have proven, hands on expertise in biomarker driven translational medicine in large pharmaceutical companies. As well as development and commercialisation of personalised medicine within biotechnology/diagnostic companies. We are passionate about developing state of the art strategies within life science companies to enable the availability of personalised medicine to all patients. Our expertise includes: Strategic planning for Translational/ Personalised medicine Biomarker discovery and validation Gene expression using formalin fixed paraffin embedded (FFPE) tissue Set up and management of early stage life science companies Diagnostic Commercialisation Regulatory compliance Reimbursement planning Investment

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PharmaWave Ltd

Paolo Bessieres, CEO

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paolo.bessieres @pharmawave.co.uk www.pharmawave.co.uk Tel: 0207 193 4588 Mob: 0796 4925349 232-238 Bishopsgate, London EC2M 4QD United Kingdom

Pharmidex Pharmaceutical Services Ltd Nicholas Traynor business@pharmidex.com

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Thanks to its extensive network of contacts, PharmaWave is able to reach decision making people in Japan and throughout Asia. PharmaWave supports Western biotech and healthcare companies by identifying the most suitable partners, structuring and negotiating corporate transactions, and keeping in touch locally with may-be partners, until after the deal has been secured. PharmaWave strongly advises Western companies wishing to enter Japan with their products and technologies to approach this market simultaneously to Europe and US, not to lose valuable royalty income. Pharmawave adopts flexible business models.

www.pharmidex.com Tel: 0870 240 5978 72 New Bond Street, Mayfair, London W1S 1RR

Pharmidex provides an extensive range of ADMET/PK (in vitro/in vivo) and safety expertise to underpin its world leading position. Existing platform technologies or bespoke studies address client specific needs and are rapidly undertaken by highly qualified scientists with academic and industry background. With extensive in-house expertise, we risk manage all project issues and associated regulatory challenges, focusing on the key data, decision-points and milestones, allowing our clients to progress their programmes and portfolio. Focused customer interaction, tailored support, high quality data, fast turnaround times and cost efficiency are attributes that makes Pharmidex your partner of choice.

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PHASTAR www.phastar.co.uk

Tel: 0207 183 7061

Unit 5 Barons Gate, 33-35 Rothschild Road, Chiswick W4 5HT

PHASTAR is a company providing statistical services to drug development companies. We are experts in the design and analysis of clinical trials

Fax: 0208 994 5730

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PHG Foundation Carol Lyon

carol.lyon@phgfoundation.org www.phgfoundation.org

Tel: 01223 741934

2 Worts Causeway, Cambridge CB1 8RN

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PHG Foundation is a registered charity whose mission is â&#x20AC;&#x153;to make science work for healthâ&#x20AC;?. We undertake policy and service development projects that accelerate the effective and responsible use of bioscience in health care. Our expert research, analysis and change management services help governments and health systems exploit developments in bioscience to improve population health. We are also a think-tank, contributing ideas and stimulating and creating space for debate on technological innovations for policy makers, health professionals and the public.

Philip Bedford Consulting Ltd pb@philipbedford.com www.philipbedford.com Tel: 0778 8410 098 234 Queen Edithâ&#x20AC;&#x2122;s Way, Cambridge CB1 8NL

Philip Bedford Consulting Limited is a Cambridge-based consultancy specializing in clinical development and regulatory services for companies developing biological pharmaceutical products targeted for licensure in Europe and the United States of America. Services include: Formulation of regulatory and clinical development strategy Creation of product development plans Preparation of regulatory and clinical documentation Advice and help with preparation for meetings with regulatory authorities Project management from laboratory bench to product licence submission Due diligence of business opportunities Philip Bedford Consulting offers a unique blend of scientific knowledge with hands-on experience covering most aspects of the biopharmaceutical development process.

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PHS

chemicals@phs.co.uk

www.phs.co.uk Tel: 01438 759850

Fax: 01438 759855 Chemical Division, Leyden Road, Stevenage SG1 2BW

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PiR Group Maurice Herring, Managing Director mh@pir-group.com www.pir-group.com

PiR Group is an international executive search firm specialising in the life sciences sectors. Established in 1990, we have a 20-year track record of placing senior business leaders from Board level to middle management across a range of key disciplines. Our client list includes over 100 life science companies from big pharma and medical devices to emerging biotech. Our personalised service, extensive market knowledge and determination to deliver results, has ensured an enviable reputation and high levels of repeat business.

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Tel: 01223 300924 18 Brooklands Court, Brooklands Avenue, Cambridge CB2 8BP

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PiR Interims Limited Sally Hope, Director of Interim Services www.pir-interims.com

PiR Interims has built a reputation, since 2005, as a significant provider of interim management solutions to international life science organizations. Our exclusive focus on the sector means that we understand the key issues and challenges faced by client companies.

Tel: 01480 499580

Functionally we provide interim managers across a broad array including Medical, Clinical Development, Regulatory Affairs, Project Management, Commercial, Marketing & Market Access, Manufacturing, Quality, HR and Finance.

3 Cabot House, Compass Point Business Park, St Ives, Cambridgeshire PE27 5JL

PiR Interims complementary businesses and alliances include Bioscience NEDs www.bioscienceneds.com placing NEDs and NECs in emerging European life science businesses; and Remtec Search www.remtecsearch.com whose expertise is in executive search for medtech companies.

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Plant Bioscience Ltd (PBL) info@pbltechnology.com www.pbltechnology.com Tel: 01603 456500 Fax: 01603 456552 Norwich Research Park, Colney Lane, Norwich NR4 7UH

Intellectual property management and technology investment / transfer: plant, microbial and biomedical science, food and nutrition. FOR RESEARCH INSTITUTIONS AND UNIVERSITIES: No fee patent management, investment in technology development and proof of concept, technology marketing, licensing, business development. FOR BIOSCIENCE COMPANIES AND INVESTORS: IP / patent management and advice, and patent due diligence services.

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TECHNOLOGIES SOUGHT: All biosciences, functional foods, agri-biotech and plant science.

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Plastid AS Rosalind Russell

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rosalind.russell@plastid.no www.plastid.no Tel: 04792 469 096

Plastid AS has a unique technology for the simple transformation of a plant’s plastid genome. New proteins or traits can be introduced into the plants that may contribute to crop improvement - pest resistance, drought tolerance etc. The technique has efficiency advantages over existing competition through simplicity and repeatability, as well as the plastid feature of no gene silencing. The transformed plants can also be used as biofactories - average protein expression levels are 10% of total cellular protein and the method can be used to express protein that cannot be made in any other system.

Prof Olav Hanssensvei 7A, 4021 Stavanger Norway

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Polytherics

Sally Waterman

www.polytherics.co.uk

The London BioScience Innovation Centre, 2 Royal College Street, London NW1 0NH United Kingdom

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sally.waterman@polytherics.co.uk

Tel: 020 7691 3561

Potter Clarkson LLP

Miss Jane Wainwright, Senior Associate

jane.wainwright @potterclarkson.com

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www.potterclarkson.com Tel: 0115 9552211

Barbara Fagg

Tel: 01462 491171

www.prescript.co.uk

15 Royston Road, Baldock, Hertfordshire SG7 6NW

PreScript is a communications agency specialising in global scientific, medical and marketing communications. Our projects are mostly commissioned by international biotechnology and pharmaceutical companies and are targeted at both professional and public audiences. Our company has particular strengths in: training and project management, copywriting, design and production, and IT, which translate into a high level of service and attention to detail. PreScript offers an exceptional combination of experienced personnel, a comprehensive skill base, timely execution, quality and a commitment to customer service and satisfaction. We work in partnership with our clients, listening closely to your requirements and feedback in order to pro-actively deliver a creative, appropriate and cost-effective solution. Whether you need help producing patient education material, product or skills training programmes, congress support, marketing materials or to revamp your website or corporate identity, then look no further. We will see your project through from concept to completion. No job is too small and no project too challenging. You can count on PreScript to deliver timely, quality material to your specifications and within budget. Our major clients include: • Novartis (multiple products/accounts) • Dako • Johnson & Johnson • Almirall • GSK

Pressplan Travel Limited www.pressplantravel.com

Tel: 01727 833291

17 Verulam Road, St Albans AL3 4DA

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The biotechnology and chemistry sectors are covered by 23 Potter Clarkson patent experts, most of whom hold a PhD in a relevant biological or chemical discipline and have research expertise in the pharmaceutical industry or academia.

PreScript Communications Ltd

Potter Clarkson LLP is a leading European firm of patent and trade mark attorneys based in Nottingham, UK. The company advises clients worldwide on patents, trade marks, designs and related aspects of intellectual property (IP). Potter Clarkson works with start-ups and early-stage companies to multinationals, turning inventions into commercial products.

Park View House, 58 The Ropewalk, Nottingham NG1 5DD United Kingdom

barbarafagg@prescript.co.uk

PolyTherics is a biopharmaceutical company that applies precision chemistry to develop improved protein and peptide-based drugs. It has developed three proprietary technologies for attaching the polymer poly(ethylene glycol) (PEG) to any therapeutic peptide or protein in a targeted fashion. PEGylation slows elimination of the protein or peptide from the body, thereby improving half-life and potentially reducing drug treatment frequency, decreasing side effects and improving patient compliance. The Company has received two rounds of investment, totalling £5.3 million, from Imperial Innovations Group plc, Longbow Capital LLP and The Capital Fund.

One Nucleus Directory 2011

PricewaterhouseCoopers LLP Tamzin Close www.pwc.co.uk/southeast Tel: 01223 460055

PwC is founded on a culture of partnership with a strong commercial focus. This is reflected in our vision:”One firm a powerhouse of a commercial enterprise that does the right thing for our clients, our people and our communities.” Our goal is to build the iconic professional services firm, always front of mind, because we aim to be the best. We set the standard and we drive the agenda for our profession.

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Abacus House, Castle Park, Cambridge CB3 0AN

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PRISM Training and Consultancy Ltd Iain Wilson

At PRISMTC, we solve problems.

iainw@prismtc.co.uk

We provide specialist statistical support to scientists and engineers.

www.prismtc.co.uk

Whatever your statistical background, we can help improve the effectiveness of your Design of Experiments, Multivariate Analyses, Six Sigma, and more....

Tel: 01223 844274 PRISM Training & Consultancy Ltd, St. John’s Innovation Centre, Cowley Road, Cambridge CB4 0WS

We provide statistical training, a consulting service and software tools.

We are based in Cambridge (UK) and we operate internationally.

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ProPharma Partners Ltd Diane Janicki djanicki@propharma partners.uk.com www.propharmapartners.biz Tel: 01293 425300 10 The Courtyard, East Park, Crawley, West Sussex RH10 6AG

ProPharma Partners is a global biopharm consultancy able to assist clients with commercial, preclinical, clinical and regulatory needs.

ProPharma Partners provides a broad and extensive range of business development expertise including strategy and partnering, pre-clinical and clinical development management services, regulatory assistance, due diligence, valuations and early stage financing advice. ProPharma Partners is present in the three major pharmaceutical markets Europe, Japan and USA and has therapeutic expertise in the major disease areas. ProPharma Partners employs a proven and successful multidisciplinary team approach working closely with clients to quickly and efficiently assist clients in achieving their business goals and initiatives.

bill.hamilton@prosarix.com www.prosarix.com Tel: 01223 870400 Prosarix Ltd, Newton Hall, Town Street, Newton, Cambridge CB22 7ZE

Prosarix specialises in the development and application of computational chemistry approaches for pharmaceutical and biotech companies, primarily focusing on drug discovery. Prosarix has developed ProtoDiscovery™, a validated, state-of-the-art computational platform with which it is pioneering novel approaches for the identification and optimisation of small molecules. The Company has three main business activities: the provision of servicedbased discovery projects for third parties; in-house discovery, developing preclinical candidates for early-stage out-licensing; and chiral products, whereby Prosarix designs novel chiral reagent panels, EnzaCore™ SAR Explorer panels, which are manufactured using specialist biocatalysis chemistry for sale to R&D medicinal chemists.

www.prosynth.com Tel: 01787 883320 Fax: 01787 883301 Unit 2 Bull Lane Industrial Estate, Acton, Sudbury CO10 0BD

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Prosynth Ltd info@prosynth.com

Prosarix Ltd Dr Bill Hamilton

For the past 16 years we have amassed significant practical production experience and have produced well in excess of 7,000 compounds, which we have supplied worldwide. We have a database of over 14,000 procedures actually carried out in our laboratories. We work closely with our customers and are equally comfortable using information supplied by our customers or developing routes to target molecules ourselves. Providing weekly updates and project reports is standard practice and our chemists are always available to discuss the work if required. ProSynth offer a very cost-effective production service to support your project - on an individual ‘fee for product basis’ or FTE project based work.

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Proteintech Europe Ltd www.ptglab.com

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Tel: 0161 226 6144 Fax: 0161 232 1272 Kilburn House, Manchester Science Park, Lloyd Street North, Manchester M15 6SE

Proteintech is a global biotech company and a renowned centre of excellence for the manufacture and supply of antibodies and proteins to the life sciences research community. With offices in the US (Chicago), UK (Manchester) and China (Wuhan) we are always available to support your research. We believe in working closely with the life sciences research community; a research partner that provides every possible antibody you might need at a reasonable price. As all the founders of the company began as bench-side researchers, we have the deepest appreciation for the high standards that all scientists hold for their projects; we hold our products to the same standard. We profoundly believe that only if you succeed, we will succeed. In addition to pre-made antibodies, Proteintech Group also provides a wide variety of custom services including: cloning, expression, peptide synthesis and custom antibody development, visit our website to find out more.

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Protogenia Consulting Ltd

Julie Warneck

www.protogeniaconsulting.co.uk

PO Box 289, Ely, Cambridgeshire CB7 9DR

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info@protogeniaconsulting.co.uk

Tel: 07905 321 515

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Timothy Broke-Smith

www.proximaconcepts.com Tel: 020 7193 3008 The London BioScience Innovation Centre, 2 Royal College Street, London, NW1 0TU United Kingdom

Tim Sparey

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Tel: 0207 400 7700

www.proximagen.com

91-93 Farringdon Road, London EC1M 3LN

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PULSE Scientific www.pulsejobs.com/uk/scientific/

Tel: 0845 459 0820 Fax: 0845 257 7926

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We also assist with R&D pharmacology, screening toxicology and ADME, (lead optimisation through to development candidate selection) identifying appropriate CROs, designing and managing contracts/studies and assisting with candidate nomination. In addition, we have a broad network of Drug Development contacts, and can provide expert advice on IP Strategy, Chemistry Process Development and Manufacture, Analytical Services, Pharmaceutical Development and Manufacture, Regulatory Affairs and Quality Assurance.

Biopharmaceutical R&D company employing proprietary oral drug delivery and discovery technologies to develop novel therapeutics and diagnostics. Technologies include: • Axcess™ - Oral delivery of macromolecules, four products in phase II • Vaxcine™ - Vaccine carrier for mucosal and parenteral administration • Mozaic™ & Lexcicon™ - Rapid & cost-effective development of personalized/targeted therapeutics or diagnostics These technologies are employed in four therapy areas by: • Diabetology Ltd - oral therapies for diabetes (www.diabetology.co.uk) • Bone Medical Ltd (ASX:BNE) - therapies for musculoskeletal diseases (www.bone-ltd.com) • Kancer Ltd - orally available and personalized therapies for cancer (www.kancer.co.uk) • Infexion - prevention and treatment of infectious diseases (www.infexion.co.uk)

Proximagen Neuroscience plc tim.sparey@proximagen.com

• strategic planning to enable early clinical development • regulatory submission document writing, review & sign-off • CRO selection, contract negotiation and management • protocol design, study monitoring and report review for toxicology, safety pharmacology and ADME studies • programme management up to EOP2

Proxima Concepts Ltd t.broke-smith@bonobo.co.uk

Protogenia Consulting Ltd offers pre-clinical development consultancy services to the pharmaceutical / biotech industry. With 15 years non-clinical outsourcing and project/programme management experience gained through virtual and medium sized pharmaceutical companies, the services we offer include:

Suite 4, The Mansion House, Chesterford Research Park, Little Chesterford, Saffron Walden CB10 1XL

One Nucleus Directory 2011

Proximagen Group is UK biotechnology company primarily focused on the development and commercialisation of novel therapeutics for diseases of the central nervous system. Proximagen is well capitalised following a £50m fund raising in June 2009 and has a broad pipeline of proprietary drug candidate programmes under development. Proximagen’s licensing interests include novel small molecules, targets with a pre-clinical or clinical proof of concept and technologies with strong patent protection in Parkinson’s disease, Alzheimer’s disease / cognition, epilepsy and neuropathic pain. Programmes in late lead optimisation through to Phase II will be considered. Proximagen also has an active out-licensing strategy including a number of clinical and pre-clinical stage assets.

Q Chip Ltd

Q Chip Ltd www.q-chip.com

Oddfellows House, 19 Newport Road, Cardiff CF24 0AA

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Quality Care Cleaning Limited Paul Heales paul@qualitycarecleaning.co.uk www.qualitycarecleaning.co.uk Tel: 01223 833300 Copley Hill Business Park, Cambridge Road, Babraham, Cambridge CB22 3XE

Quality Care is a leading independent provider of commercial cleaning services to customers in Cambridge and a 30 mile radius.

Trading for 30 years, the Company has developed particular expertise working with life science and pharmaceutical companies.

The company provides daily office cleaning and laboratory cleaning to a range of premises and is experienced in servicing laboratory situations. Quality Care is an ISO 9001 registered company and can provide complete Health and Safety documentation for the services that we provide.

As a partner in the One Nucleus Support Supplier scheme, discounts are available to members according to their level of membership.

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Queen Mary Bioenterprises Ltd Dr Ramsay Richmond r.richmond@qmul.ac.uk www.qmbioenterprises.com Tel: 020 7882 8952 42 New Road, Whitechapel, London E1 2AX

The Queen Mary BioEnterprises Innovation Centre (QMB) based in London E1 is an incubation and follow-on space for bioscience and environmental companies. QMB provides 39,000 sq ft of modern, laboratory and office space. It is situated on the research campus of Bartâ&#x20AC;&#x2122;s and The London School of Medicine and Dentistry, providing tenants with a wealth of local advice and expertise.

Accommodation is available in suite sizes from approx. 500 sq ft to 2,100 sq ft, with competitively-priced leases to other London-based offerings. QMB is just one mile from the City of London, and seven minutesâ&#x20AC;&#x2122; walk from Whitechapel Underground station.

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Queen Mary College

www.qmul.ac.uk Tel: 0207 882 7867

Fax: 0208 983 1007 Barts and the London School of Med & Dent, Blizard Building, 4 Newark Street, London E1 2AT

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Queen Mary Innovation Ltd

www.qminnovation.co.uk

Tel: 0207 882 5278 Queen Mary University of London, Mile End Road, London E1 4NS

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Quest Diagnostics Clinical Trials Lynn Murphy

Quest Diagnostics Clinical Trials- Providing Unique Solutions for Drug Development

lynn.x.murphy @questdiagnostics.com

• One of the largest central laboratory and biomarker companies • More than 600 employees • Operates in 4 proprietary labs (USA, UK), complemented by 5 alliance labs (China, India, Singapore, South America and Australia) • Broadest test menu in the industry, with experience in central lab (safety) and more than 500 validated esoteric and routine biomarker assays • Proprietary predictive biomarker assays already in use in clinical programs • Broad therapeutic expertise • Global supply chain and logistics expertise • High-calibre project management team • Real time data access via Result/View™

www.questdiagnostics.com/ clinicaltrials Tel: 07827 350 352 Unit B1, Parkway West, Cranford Lane, Heston, Middlesex, TW5 9QA

Questrax Ltd

www.questrax.com

Stoneacre, Binscombe, Godalming GU7 3QL

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Raumedic Mark Laycock Mark.laycock@raumedic.com

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www.raumedic.com Tel: 07802 333 916 Hill Court, Walford, Ross-on-Wye, Herefordshire HR9 5QN

RAUMEDIC have established a reputation for supplying high quality medical tubing and injection moulded products for a variety of medical applications including Extra Corporeal Circulation, Dialysis, Enteral Feeding and speciality catheters, and are approved suppliers to most of the leading international medical device companies. RAUMEDIC offers a one-stop development and manufacturing program for medical tubing, injection moulding and full low volume to high volume contract manufacturing services. Our engineers will work with you to advise on materials, design and construction, together with packaging and sterilisation. We also offer full Regulatory support to enable you to CE mark your medical devices.

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Reading Scientific Services Ltd Rebecca Thomas enquiries@rssl.com www.rssl.com Tel: 0118 9868541

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Fax: 0118 9868932 Reading Scientific Services Ltd, Reading Science Centre, Whiteknights Campus, Pepper Lane, Reading RG6 6LA

Recombinant Antibody Technology Ltd Tel: 01223 497170

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Maia Building 270, Babraham Research Campus, Cambridge CB22 3AT

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We provide a comprehensive range of services including: pharmacopoeial testing, release testing, residual solvent analysis, dissolution testing, method development, stability storage management, microbiology, spectroscopy, physical sciences, microscopy, clinical sciences and training. We continually invest in technology and people to ensure our business maintains its foundation in scientific excellence. Our multi-disciplinary teams guarantee to meet your needs for rapid results, expert personal interpretation and sound advice. We operate within a framework of accredited quality systems and have gained extensive regulatory compliance having been inspected by the MHRA and US FDA.

One Nucleus Directory 2011

Reddie & Grose Chartered Patent Attorneys & Trademark Attorneys enquiries@reddie.co.uk www.reddie.co.uk Tel: 01223 360350 Fax: 01223 360280 5 Shaftesbury Road, Cambridge CB2 8BW

With a client base representing companies from the FT Global 500 and FTSE listed companies, Reddie & Grose is recognised as a leading patent and trade mark firm. In 2009, the Managing Intellectual Property global patent survey ranked the firm as one of the UK’s top patent prosecution advisors. It consistently continues to achieve high rankings in all professional surveys. Reddie & Grose prides itself on delivering intellectual property protection for businesses in both the domestic and international marketplaces with a strong professional team of over 30 people from varied scientific backgrounds. The firm’s Cambridge office offers particular expertise in biotechnology, pharmaceutical, chemical, engineering, cleantech, instrumentation, medical device, materials, and software related inventions. Companies/academic institutions represented in this field by Reddie & Grose include: Diagnostics for the Real World, Haemostatix, Funxional Therapeutics, TCP Innovations, Trillion Genomics, Brax, Cambridge Biopolymers, Metalysis, University of Cambridge, Cambridge Broadband, i2, Cambridge Biotechnology Ltd and nCipher. Talk to us ...

www.remtecsearch.com Tel: 01223 550860 Fax: 01223 847630 Unit 1, Breaks House, Mill Court, Great Shelford CB22 5LD

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Remtec Search & Selection Ltd enquiries@remtec.co.uk

Remtec Search and Selection is a Cambridge UK based specialist executive search company working across the lifescience and medical device industries. Remtec manage UK and international search assignments for a range of roles including those listed below. Our many years of industry expertise as well as our research and project management experience enable us to manage search assignments in a high quality and timely manner. We work with large global corporations as well as small investor backed start up companies. We can offer a range of flexible service levels enabling us to tailor our offer to meet the timescales and budget requirements of our clients. Search Assignments we undertake: CEO HR and Finance General Managers Health Economics Sales and Marketing Regulatory Affairs Quality Managers Technical and Clinical.

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Richard Anderson PR Richard Anderson PR provides senior level public relations and broader communications advice to entrepreneurial healthcare and life science companies. We provide a dynamic, strategic PR resource dedicated to building reputations that reflect and amplify the successes of our clients.

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Riverbank IT Management Ltd Chris Jones, Business Development Manager

Riverbank helps growing bioscience companies by taking responsibility for all aspects of their IT. It provides all the facilities that a company would expect if they had their own IT department.

Chris@riverbank.co.uk

Over 100 companies depend on Riverbank as their outsourced IT department. They benefit from fixed IT costs, a help desk, and management of their vital IT infrastructure – in their office, working remotely or in the cloud.

www.riverbank.co.uk Tel: 0203 384 2822 Oxford Office: 01844 278036 Standhill Court, Little Haseley, Oxford OX44 7LN

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Riverbank is a Microsoft Gold Partner with a Small Business Specialist qualification, and an accredited Investor in People.

All work comes with a guarantee to provide unbiased advice. As one client commented about Riverbank, “You’re on our side”.

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RNID

www.rnid.org.uk

19-23 Featherstone Street, London EC1Y 8SL

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Royal Veterinary College Royal College Street, London NW1 0TU

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RSA Consulting Limited

Dr Kay Wardle

www.theRSAgroup.com

Fax: 01707 271366

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kay.wardle@thersagroup.com

Tel: 01707 259333

RSA is a global leader in the provision of Executive Search, Interim Management and Talent Lifecycle Services to the Life Sciences industry with offices in China, Germany (2), Singapore, Switzerland, UK (2) and USA. With three decades of specialist experience, our expert team supports you in attracting, retaining, developing and making the most of your talent, wherever and whenever you need to. To discuss your organisation, its strategy and how people will contribute to your success, call us now.

The Melon Ground, Hatfield Park, Hertfordshire AL9 5NB

Ruston Poole International plc www.rustonpoole.com Tel: 0207 930 3001

Fax: 0207 7930 3002

Cording House, 34 St James Street, London SW1A 1HD

Europe’s leading Executive Search firm specialising in the healthcare industries, including pharmaceuticals and biosciences, across all functions. Our core expertise lies in international executive search for senior management positions, as well as for Board Directors (including Non-executive Director and Chairman positions). We also work in the US, SE Asia and Australia through our regional branch offices and associate companies, details of which may be found on our website. Key Contacts: David Collingham Executive Chairman Paul Edwards, MBE, Chief Executive Officer.

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RWM Data Management Limited Bill Stolworthy bstolworthy@rwm.co.uk www.rwm.co.uk Tel: 0844 800 4896 Fax: 01493 667657 Hewett Road, Gapton Hall Ind. Est, Great Yarmouth, Norfolk NR31 0NN

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We have current contracts with several Government Agencies including the Serious Fraud Office, HMRC and the CPS. These require all of our employees to be cleared to SC level allowing us to handle documents marked as Secret. Our procedures have been developed to enable us to guarantee the security and confidentiality of your documents. RWM has also worked with major companies in the life science sector and our staff are fully experienced in handling Essential Documents relating to the regulatory authorities.

RWS Group - Medical Translation Division Charles Morris Denholm

RWS Group - Medical Translation Division

charles.morris-denholm@rws.com

Specialising in medicine and pharmacology for more than 50 years, we serve many of the world’s leading pharmaceutical companies, CROs, medical device manufacturers and medical communications agencies. Translating from and into over 50 languages, we are equipped to handle projects of any size or complexity. ISO 9001 accredited. Translations into English from the more common languages are produced mostly in-house by a team of highly qualified, subject specialist translators and editors, supported by RWS’ strict quality procedures. Work out of English is produced in the target country and also subject to the same rigorous quality controls.

www.rws.com

RWM has been providing high quality data management and document scanning services since 1994. Our expertise is in dealing with extremely important and sensitive documents.

Tel: 020 7554 5400 RWS Group, Tavistock House, Tavistock Square, London WC1H 9LG

One Nucleus Directory 2011

S-Tech Insurance Services Ltd www.s-tech.co.uk Tel: 01223 324333 Fax: 01223 464150 154-156 Victoria Road, Cambridge CB4 3DZ

We have successfully supported Life Science and related industries since 1982 by arranging insurance cover for a wide range of asset, liability and financial risks. Our aim is to fully understand your business including the operating and financial exposures to achieve the widest possible protection. We are fully independent brokers with access to a broad range of UK and overseas insurers including the Lloyds market. Our clients range from Start Up Companies to International Organizations. We have a wealth of experience in supporting new ventures through their growth cycle to the conclusion of a successful trade sale exit, merger, acquisition or an IPO.

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SafeBox James Merrells sales@thesafebox.co.uk www.thesafebox.co.uk Tel: 01223 291133

Safebox offers bespoke storage solutions for the lifelong management of all archival data, including physical files and all back up media. Storage areas are secure, fire rated and dehumidified to maintain the integrity of all stored material. Daily deliveries across the Eastern region, including 2 hour delivery for items required urgently, ensures easy recall of items as and when required. Back up rotations to suit your schedule and disaster recovery deliveries are available. Barcode technology guarantees the traceability of all items throughout storage areas, during transit and whilst with customers. Servicing clients across a wide range of sectors and meeting the stringent audit criteria of meditech and biotech research companies. As an ERBI Support Supplier excellent rates of storage and management are available to member organisations. To enquire about our ERBI rates or for any other queries please call 01223 291133 (Option 2) or email sales@thesafebox.co.uk

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Sagentia Ltd (UK) Katharine Oldak katharine.oldak@sagentia.com www.sagentia.com Tel: 01223 875200 Harston Mill, Harston, Cambridge CB22 7GG

Sagentia is a technology and product development company, working with clients from front end needs analysis to transfer to manufacture to deliver real commercial value.

Established in 1986, Sagentia operates in the medical, industrial and consumer products sectors worldwide. Our uncompromising commitment to innovation has led to the launch of new technologies and products that change the basis of competition for our clients. The company also assists business leaders to create strategies for technology, innovation and growth.

We can work with you wherever you are in the world. Our resources are situated in state-of-the-art facilities in Europe, the USA and China.

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Sagittarius IP Dr. Mark Gibson camb@sagittariusip.com www.sagittariusip.com Tel: 01223 833933 Sagittarius IP, 3 The Mill, Copley Hill Business Park, Cambridge Road, Babraham, Cambridge CB22 3GN

Sagittarius IP are a firm of Chartered and European Patent Attorneys who specialise in chemical, pharmaceutical and biotechnology subject matter. We provide the following services: • ‘invention spotting’, drafting, filing and prosecution of patent applications and representation before the UK and European Patent Offices, including oppositions and other contentious work • filing of international patent applications (PCT) and control of worldwide patent prosecution - advice on IP strategy • freedom to operate investigation • IP due diligence and • IP education Sagittarius IP was set up in 2002. On 1 April 2009, Sagittarius IP opened a Cambridge office and Mark Gibson was appointed Managing Partner of the Cambridge office. In Aug 2009, the Cambridge office relocated to larger premises in Babraham.

SANYO E&E Europe BV Zoe Millington zoe.millington@sanyo.com www.sanyo-biomedical.co.uk Tel: 01509 265265 SANYO E&E Europe BV, 9 The Office Village, North Road, Loughborough, Leicester LE11 1QJ

SANYO E&E Europe BV manufacture’s, supplies and services specialist laboratory equipment. SANYO’s core expertise is in the fields of Incubation, Refrigeration and Sterilization. SANYO Incubators suit a wide range of applications with some offering unique features such as Hydrogen Peroxide Decontamination Systems for GMP applications, precision Temperature and CO2 control systems and Zirconium controlled CO2/O2 Mixed Gas Environments. Refrigeration products provide temperatures in many ranges down to as low as -190C including mechanical freezers providing -152C. Portable Autoclaves are available in a range of sizes. Service also includes Validation and Calibration packages.

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The School of Pharmacy, London www.pharmovation.com

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Tel: 0207 753 5967

The School’s primary research areas are in pharmaceutical formulation research and targeted drug delivery. We offer consultancy and collaboration in these areas. The School is active in licensing of patented inventions and spinout formation.

Fax: 0207 753 5968 29-39 Brunswick Square, London WC1N 1AX

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Schwartz Communications

www.schwartzcomms.com

Fax: 0208 973 2631

Public relations, marketing communications, strategic planning and media training.

Tel: 0208 973 2630

2 Sheen Road, Richmond TW9 1AE

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Science Warehouse Ltd info@sci-ware.com www.sci-ware.com

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Tel: 0113 3844200 Fax: 0113 3844201 Suite B2, Half Roundhouse, Roundhouse Business Park, Wellington Road, Leeds LS12 1AH

Declan Cunningham declan@selectiveantibodies.com www.selectiveantibodies.com Tel: 01732 468672 Mobile: 07887 633888

Contact us today to find out how you can benefit from a triple whammy of benefits: cash savings, greater productivity and spend control.

Selective Antibodies Ltd is a UK based diagnostics company with the prime focus of overcoming key technological problems central to the production of high performance point of need systems for small target molecules such as: medicaments, natural and unnatural toxins (such as fungal toxins and pesticides), drugs of abuse, CBRNE substances, and other substances of importance to forensic investigation, the environmental and food and water industries.

Fax: 01732 459541 Selective Antibodies Ltd, 145 High Street, Sevenoaks, Kent TN13 1XJ

Sera Laboratories International Ltd Unit 44, Bolney Grange Business Park, Haywards Heath RH17 5PN

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Our partnership with One Nucleus delivers a dedicated web-based purchasing solution for members – providing big company benefits to businesses at all stages of development. Implementation is fast so making savings on your purchasing is as easy as Search, Compare, Save.

Selective Antibodies Limited

www.seralab.co.uk

We’ve been delivering web-based purchasing solutions to leading life sciences organisations for a decade. Our e-procurement solution is loved by scientists and purchasing professionals alike providing fast, efficient and controlled spend.

One Nucleus Directory 2011

Seroba Kernel Life Sciences Limited www.seroba-kernel.com 15 Molesworth Street, Dublin, Ireland 2

Seroba Kernel is a pan-European life science venture capital firm with funds under management of Euro100m. The firm is currently investing from its second fund, which achieved a Euro75 million first close in 2009. Seroba Kernel invests across the spectrum of the life science industry including therapeutics, diagnostics, medical devices and other selected opportunities that have the potential to fundamentally change medical care. The fund focuses on innovative opportunities that address market needs, investing on average Euro5-7 million over the life of each investment. Seroba Kernel has an experienced venture team based in Dublin and London.

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Shant Laboratories Ltd www.shantlabs.com Tel: 0208 998 3820

Shant Laboratories is the developer and the sole manufacturer of Pathfinder high performance liquid chromatography (HPLC) columns.

14 Amherst Avenue, Ealing, London W13 8NQ

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Sigma-Aldrich customerservice@ sigma-aldrich.com www.sigma-aldrich.com

Sigma-Genosys is a leading supplier of custom synthetic DNA (oligos) and synthetic peptides to the life science research community. Synthesis of oligonucleotides and peptides uses patented, high throughput instrumentation. Sigma-Genosys is part of Sigma-Aldrich Company Limited.

Tel: 01440 767000

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Fax: 01440 767099 Fancy Road, Poole BH12 4QH

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Simbec Research Ltd www.simbec.co.uk Tel: 01443 694309 Fax: 01443 692499 Merthyr Tydfil Industrial Park, Cardiff Road, Merthyr Tydfil CF48 4DR Wales

Services offered: Phase I Safety, Tolerability and PK/PD Studies in Healthy Volunteers & Phase IIa Proof of Concept Studies in Patients. Bioanalysis, including Assay Development. Central Laboratory Data Management and Statistics Quality Assurance Human Pharmacology Consulting Niche Services include: Simbec Scintigraphy - gamma scintigraphic imaging for proof of concept of drug delivery systems SimTest dermatology service for the development of dermatology products and transdermal drug delivery systems. All facilities on one site. Specialist in First-into-Human, Phase I Studies. Optimized services for faster recruitment and study completion. Services tailored for Biotech companies requiring advice on development of new active substances, particularly early (Phase I IIa) exploratory and confirmatory clinical research.

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Simon Greene Associates Specialist provider of business communications, including online video, podcasts, multimedia, presentations and live events. Track record in supporting biotech companies and the scientific community in Cambridge and the East of England.

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Smerud Medical Research UK Ltd Mr. Paul Cronin, Business Development Manager paul.cronin@smerud.com

www.smerud.com

Manchester Science Park, Units 10 & 19, Enterprise House, Lloyd Street, North Manchester M15 6SE

Tel: 0845 803 9665

Smerud Medical Research is a clinical Contract Research Organisation operating in the European area with offices in Denmark, Finland, Norway, Poland, Russia, Sweden and United Kingdom. Our activities are focused on general drug development consulting, executing clinical project management, monitoring of phase I-III studies, regulatory affairs, data management and medical writing projects. The company employs about 80 persons, of whom 65 are clinical research, regulatory or biostatistical professionals. We have been operating since 1993 with involvement in more than 600 clinical trials and more than 300 regulatory projects, in addition to approximately 100 projects related to data management, biostatistics and medical writing.

Softwerx Ltd

Sean Kiernan

Research and development organisations face unique challenges on a daily basis - IT should not be one of them.

Sean.kiernan@softwerx.com

www.softwerx.com

Softwerx has a renowned track record for delivering value. We give our clients time to focus on core operations by delivering a range of proactive IT services at an agreed fixed monthly cost.

1 Riverside, Granta Park, Cambridge CB21 6AD United Kingdom

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Tel: 01223 834333

With over a decadeâ&#x20AC;&#x2122;s experience, we have a proven track record in delivering projects on-time and on-budget, typically saving our clients circa 40% year-on-year. Our clients include both local and national organizations like Oval Medical, Kidney Research UK, Cambridge Assessment and ARM.

Somaxa Ltd www.somaxa.com Tel: 07747 765 069

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40A Market Square, St Neots PE19 8DX

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South Cambridgeshire District Council www.scambs.gov.uk Tel: 01954 713 454 South Cambs Hall, Cambourne Business Park, Cambourne CB23 6EA

South Cambridgeshire District Council is a Local Authority. The District is the second largest district in Cambridgeshire. It completely surrounds Cambridge City and shares its boundaries with Huntingdonshire, Fenland and East Cambridgeshire on the northern part of its borders. In the south the district has boundaries with Bedfordshire, Hertfordshire, Essex and Suffolk. South Cambridgeshire is highly rated in independent surveys scoring highly on factors such as house prices, labour market, environment, education and health. South Cambridgeshire has played a key part in the economic growth of the Eastern Region. It successfully combines traditional industry such as agriculture and engineering with new sectors such as IT and biosciences, many of which are situated on state of the art business and science parks. It is well connected to the regional, national and international communications network, including airports, sea, rail and road transport.

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SPD Development Company Limited Dr Adam Hajjar, External Opportunity & Business Intelligence Manager adam.hajjar@spdspark.com

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www.swissprecision diagnostics.com Tel: 01234 835472 SPD Development Company Ltd, Priory Business Park, Stannard Way, Bedford MK44 3UP

One Nucleus Directory 2011

Swiss Precision Diagnostics (SPD) is a consumer diagnostics company formed in May 2007 as a 50/50 joint venture between the world leading medical diagnostics and consumer products companies Alere (formerly Inverness Medical Innovations) and Procter & Gamble. SPD is currently interested in identifying new diagnostic technologies/products to support/improve its existing products and to fill its product pipeline. Examples of technologies being sought include novel sampling systems, disease/condition biomarkers, assay reagents, assay systems, signal creation and detection systems and high sensitivity diagnostic technology platforms. SPD are looking for collaborations with academic/research organisations and companies with relevant diagnostic technologies and/or products.

SRA Global Clinical Development

info@constellagroup.com

www.constellagroup.com Tel: 01235 437400 Fax: 01235 437437

20 Milton Park, Abingdon OX14 4SH

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SRG Executive www.srg.co.uk Tel: 0161 868 2201 11th Floor, Trafford House, Chester Road, Stretford, Manchester M32 0RS

Having pioneered contract recruitment for the scientific community in the early 1990’s, our executive recruitment operation was established more than a decade ago and is retained by clients ranging from multi-national pharmaceutical businesses to SME and start-up organisations. Our portfolio of successfully delivered search assignments is as wide and varied as our client base and includes highly complex technical appointments as well as many confidential commercial roles, all carried out within the sensitive world of life sciences and biotechnology. Our Consultants carry out all research in-house and possess an unrivalled knowledge and expertise within this niche market, meaning all clients are assured of a truly expert consultation and search process Interim Management All our Interim executives are ‘career interims’ with impressive track records of adding value within a wide variety of organisations where specific business skills, technical expertise or change management and systems knowledge are required on a project basis. All assignments are costed on a case by case basis and are tailored to your specific requirements or recruitment budget.

www.stjohns.co.uk Tel: 01223 420252 St John’s Innovation Centre, Cowley Road, Cambridge CB4 0WS

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St John’s Innovation Centre Ltd David Gill

St John’s Innovation Centre was established by St John’s College in 1987 to provide early stage knowledge-based companies with business advice, strategic consultancy, introductions and flexible accommodation. The Centre is located at the heart of the Greater Cambridge technology cluster, in which it plays a pivotal role. The Centre offers business address and serviced office accommodation to early-stage businesses through a full business incubation service, incorporating a range of support, training and advisory facilities. As part of a vibrant community with an entrepreneurial spirit, tenants are start-up and early-stage companies operating in a wide range of technologies.

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Stabilitech Ltd www.stabilitech.com Tel: 0207 594 6146 Fax: 0207 594 6119 Imperial Incubator, Bessemer Building Level 1, Imperial College, London SW7 2AZ

Stabilitech has developed a proprietary technology for stabilisation of vaccines and biopharmaceuticals, removing the need for refrigeration. Stabilitech started research in late 2004, and received its first significant funding in 2007, from business angels. Stabilitech has developed a novel proprietary technology which stabilizes vaccines (including live viruses, inactivated viruses and subunit vaccines), biopharmaceuticals (including antibodies, enzymes, growth factors etc) and other biological products. Stabilitech is based in the Imperial College incubator, and currently has 12 employees.

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STARLAB (UK) Ltd infoline@starlab.co.uk www.starlab.co.uk Tel: 01908 283800

STARLAB are liquid handling specialists whose success is founded on their expertise in automated injection moulding processes for the manufacture of high-quality laboratory consumables. STARLAB’s portfolio includes, alongside its own TipOne pipette tip range and award-winning ErgoOne pipettes, an extensive range of laboratory consumables, disposable gloves, benchtop equipment and sample storage solutions, as well as a competitive UKAS accredited pipette calibration service. As an ISO 9001 accredited company, STARLAB provides a high quality service from order through delivery to after sales care. STARLAB was one of the first UK companies in its sector to be awarded the ISO 14001 for their day-to-day environmental management and award-winning plastic laboratory waste recycling service. STARLAb’s green office and warehouse policy mirrors their ‘REUSE! REFILL! RECYCLE!’ philosophy of their TipOne Pipette Tip system.

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Sterling IP www.sterlingip.co.uk

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Tel: 01707 358636 Fax: 0208 428 3301 BioPark, Broadwater Road, Welwyn Garden City AL7 3AX

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Stratagem IPM Ltd

mail@stratagemipm.co.uk

Tel: 01223 550740

Fosters Wing Anstey Hall, Maris Lane, Trumpington, Cambridge CB2 9LG

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www.stratagemipm.co.uk

Fax: 01223 550748

Stratagem Intellectual Property Management Ltd is a full-service, Cambridge UK-based, out sourced intellectual organisation and management company with global reach. Stratagem IPM Ltd fills a developing need within industry for the provision of strategic advice and intellectual property management for life science, medtech, cleantech and high technology companies. Stratagem’s qualified patent and trade mark attorneys use a commercial perspective and hands on management approach to enhance the value of IP assets.

Swanton Associates Ltd Tel: 01362 637724 Pond Farm, 40 Greengate, Swanton Morley, Dereham NR20 4ND

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Sygnature CSL www.sygnaturechem.com Tel: 0115 941 5401

Founded in 2004, Sygnature CSL provides premium Med. Chem, Synthetic and Computational Chemistry Services from it’s state of the art facilities in BioCity Nottingham.

BioCity, Pennyfoot Street, Nottingham NG1 1GF

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Synapse Clinical Research Services Ltd www.synapsecrs.co.uk

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6 Harding Way, St Ives PE27 3WR

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Synapse Clinical Research Services is a flexible and independent QA consultancy. It provides a range of GCP and GMP Quality Assurance Services tailored to meet client’s needs. Services include MHRA inspection preparation, internal system and facility audits, process improvement, GCP and GMP training, SOP writing and review. Synapse also undertakes supplier audits with particular expertise and experience in Clinical Trials Manufacture and Packaging, Clinical Research Organisations, Phase I Units and Clinical Laboratories.

Synapse Medical Resourcing Ltd Dr Stephen Jones sjones@synapsemr.com www.synapsemr.com Tel: 0207 692 0555 100 Eton Place, Eton College Rd, London NW3 2DT

Synapse Medical Resourcing Ltd are dedicated to finding companies talented medical doctors, at every level. Founded by a pharmaceutical physician Synapse has excellent contacts with medical organisations and networks allowing us to find the best candidate for the role. Synapse has built good working relationships with pharmaceutical companies and physicians, providing an excellent service for both. By taking the time to get to know and understand our clients needs, we find the most suitable partnerships. For Recruiters: Company requirements are reviewed, and our candidates screened by an experienced pharmaceutical physician ensuring that only the most suitable candidates are submitted for interview. For Jobseekers: We provide candidates with all the required information to decide whether a job is right for them. Our support helps candidates obtain the role they want and most suited to their needs.

Gostling House, Diss Business Park, Hopper Way, Sandly Lane, Diss IP22 4GT

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Syne qua non www.synequanon.com

Syne qua non is the preferred clinical development partner for many pharmaceutical and biotechnology companies in the UK, Europe and the rest of world. They have a breadth of experience in many therapeutic areas as well as clinical development phases. Noted for their flexibility they support the diverse needs of large and small organisations alike but always provide the assurance that advice and services offered will always meet development and regulatory needs. Specialist service in: Data Management Statistics consultancy Data analysis and reporting CRF Design Medical Writing Quality Assurance auditing Electronic data collection systems deployment & support.

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Takeda Pharmaceuticals www.takeda.com 61 Aldwych, Suite 300, London WC2B 4AE

Takeda Cambridge is a drug discovery company specialising in identifying and validating novel drug targets derived from the human genome alongside well-established literature targets. Worldwide, Takeda develops, manufactures and markets a broad range of superior pharmaceutical products to strive toward better health for individuals and progress in medicine. Our key therapeutic focus is in metabolic disease and CNS disorders.

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Talentmark enquiries@talentmark.com www.talentmark.com Tel: 0845 095 2626 Vintage House, 37 Albert Embankment, London SE1 7TK

Main Contact for Communications: Sharon Shields, Consultant Other Consultants: Richard Adams - VP Bill Steggals - VP David Nolan - VP Expertise: First in this specialist field and still setting the standard in executive search and selection. Recruitment to the most senior levels in all key functional areas. Nine full-time consultants with broad â&#x20AC;&#x2DC;hands onâ&#x20AC;&#x2122; experience, spanning most sectors of the pharmaceutical and healthcare industries. Specialist in-house research team, with multilingual and global capability. Extensive UK and international coverage, with recruitment success in more than 30 countries. Services: Comprehensive recruitment service, primarily by executive search, but also using advertised selection, TalentBank the candidate database service and interim management. Associated companies in Continental Europe, USA, Australia and South Africa.

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Tangent Reprofiling www.tangentreprofiling.com

Tangent has a lab based technique to identify drug-protein interactions for their own R&D pipeline.

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Central Point, 45 Beech Street, London EC2Y 8AD

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TCG Medtech www.tcgmedtech.com

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Tel: 919-941-0700

We develop sales and markets for innovative medical products, with a strong focus on helping companies develop their transatlantic business – in either direction.

1009 Slater Rd, Ste 450, Durham NC-27703 United States

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Team Consulting Ltd

info@.team-consulting.com

Tel: 01799 532700

Abbey Barns, Duxford Road, Ickleton, Cambridge CB10 1SX

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www.team-consulting.com

Fax: 01799 532701

Team is a leading product development consultancy working primarily in the pharmaceutical and healthcare industry. We’re acknowledged experts in medical and drug delivery device development and we work globally with all kinds of companies, from start-up ventures to multinational organisations. We help our clients at all stages of the product development process. If you need to ensure you have the right product strategy, we can help you map the future. If you need to assess a licensing opportunity, we have a wealth of experience in technical due diligence. We’ll bring creativity to generating product concepts, then test them with hands-on user trials. We can guide a product safely through every stage of development to industrialisation, and throughout we’ll manage and minimise risk. As you’d expect, we have an outstanding team of industrial designers and mechanical, software and electronics engineers, and we’re accredited to ISO 9001-2000. We pride ourselves on the quality and independence of our advice, and the relationships we build with our clients. We will sometimes consider working with companies at reduced rates in return for equity or royalties. Team services: Product Strategy, Product Engineering, Due Diligence, User Research, Industrial Design, Risk Analysis, Industrialisation.

Technomark Life Sciences

www.technomarkls.com

Crown House, 72 Hammersmith Road, London W14 8TH

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Terry Parlett Tel: 0207 188 3846 3rd Floor Chapel House, Great Maze Pond, London SE1 9RT

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Tessella plc www.tessella.com

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Tel: 01438 749886 Elopak House, Meadway Technology Park, Rutherford Close, Stevenage SG1 2EF

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Tessella solves problems and adds value to our clients’ businesses through the application of scientific methods and information technology. Innovative Informatics and Consultancy for RD Tessella has worked with some of the biggest names in the pharmaceutical industry for over 30 years. We help clients address a wide range of business goals, including, improving efficiency and productivity in drug discovery, delivering the business benefits of translational medicine, and faster more effective clinical trials. What makes our technology and consulting services effective is our understanding of both the science and informatics of pharmaceutical RD, as well as unique software assets and intellectual property that reduce project risk, cost and time. With offices in Europe and North America, global companies rely on Tessella for business critical assignments.

Thomson Reuters (Scientific) Ltd

www.thomsonreuters.com Tel: 0207 433 4384

The Johnson Building, 77 Hatton Garden, London EC1N 8JS

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Total Cost of Ownership Support

Tel: 01763 247681

161 The Causeway, Bassingbourn, Royston SG8 5JD

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Total Scientific www.totalscientific.com Tel: 01223 835968 Babraham Research Campus, Cambridge CB22 3AT

We provide a range of biomarker services to clients, to assist with many aspects of the drug discovery process and development of novel diagnostic tests.

These services include:

• Biomarker discovery • Bioanalysis

• Clinical studies • Data management and biostatistics

• Assay development

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TPP Global Development Ltd sales@ttplabtech.com www.tppgd.com

Drug development company based in Edinburgh looking to in-license novel IP from universities, research institutes and industry sources.

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Tel: 0131 523 1424 10 York Place, Edinburgh EH1 4EP UK

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Tranziger Limited

www.tranziger.com

Tel: 0208 563 0368 Fax: 0870 705 2028

Lygon House, 50 London Road, London Borough of Bromley, Bromley BR1 3RA

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TTP LabTech Limited Jason Mundin

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sales@ttplabtech.com www.ttplabtech.com Tel: 01763 262626 Fax: 01763 261964 Melbourn Science Park, Cambridge Road, Melbourn, Royston SG8 6EE

Tudor Reilly

www.tudor-reilly.com

Fax: 01494 680 130

TTP LabTech provides an integrated suite of products and services to support research in the healthcare, biotech, pharmaceutical and academic sectors. By covering a wide range of application areas including sample management and storage, low volume liquid handling, fluorescence based assay platforms, work flow management and data management software and cell based contract research services; TTP LabTech can support life science research by improving the efficiency and throughput of data generation. If you would like further information concerning TTP LabTech’s products and services visit us at www.ttplabtech.com, email us at sales@ttplabtech.com or call us on +44 (0) 1763 262626.

Tel: 01494 687 862

Wilson House, 23 London End, Beaconsfield HP9 2HN

Tudor Reilly is a fast-growing corporate communications agency focused on healthcare. Established in 2007, Tudor Reilly has a growing client base both in the UK and internationally. Tudor Reilly has two outstanding characteristics – a hands-on senior team, with experience in journalism, broadcast media, healthcare PR, marketing and sales and a rigorous approach to project implementation. The team combines in-depth media knowledge with a solid understanding of science and the pharmaceutical industry to provide strategic counsel and high-level coaching to companies involved in developing the medicines of tomorrow. Media relations Leadership conferences Corporate positioning Franchise positioning Issues and crisis support Media training Presentation skills Digital media For more information visit www.tudor-reilly.com

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Tukan Partners Ltd www.tukanpartners.com Tel: 01223 719518

Fax: 01223 719518

166 Gilbert Road, Cambridge CB4 3PB

Tukan Partners is able to provide both strategic and transactional regular, hands-on input and support to its’ partners’ commercial activities. Nigel Crockett, Director of Tukan Partners has more than 15 years of industrial experience in the biotech-pharma business and has an established and respected commercial network which has resulted in the closing of a multitude of highly valuable, sector-leading collaboration and licensing deals.

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TWI Ltd www.twi.co.uk

Tel: 01223 891162

Granta Park, Great Abington, Cambridge CB21 6AL

Fax: 01223 891284

TWI is one of Europe’s largest independent research and technology organisations. TWI is a non-profit distributing, membership based company, with 3,500 members from 60 countries around the world. Over 520 skilled staff are dedicated to helping industry apply new materials and manufacturing technologies efficiently and cost effectively. Over the last 20 years, TWI has built up its capability to support the medtech and diagnostics sectors, covering such topics as: drug delivery, implantable devices, orthopaedics, ultrasound devices, novel coatings and packaging. It supports members through its engineering, materials and manufacturing expertise, as well as in sourcing funds for collaborative R&D. TWI is one of the UK’s leading organisations attracting funds from national and European funding programmes. TWI is also a core partner in the Technology Strategy Board’s HealthTech & Medicines KTN.

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Ubichem plc www.ubichem.com

Tel: 02380 258 319 Fax: 02380 263 013

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Mayflower Close, Eastleigh SO53 4AR

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Ubichem provides a comprehensive range of chemistry services (on lab to pilot plant scale) to support pharmaceutical development and meet your drug substance requirements: • cGMP API and intermediate manufacture for preclinical and clinical trials • Process Research and Development • Process validation • Salt screening and crystallisation studies • Stability studies (stress tests, accelerated and long term) • Analytical method development and validation • Radiolabelling • Impurity profiling • Synthesis of Impurities and Reference Standards. Our experienced team minimise the risks associated with scaling up medicinal chemistry routes, and have particular expertise in heterocyclic and organometallic chemistry. We are approved by the regulatory authorities for the manufacture of API from preclinical through to commercial supply. Reliability and excellent problem-solving skills make Ubichem a preferred partner for many pharmaceutical and biotech companies.

Universal Sensors Ltd www.universalsensors.co.uk Tel: 01799 533 160 Unit 4, Abbey Barns, Duxford Road, Ickleton CB10 1SX

A Universal Sensors designs and manufactures biosensors that are sensitive, fast and versatile. Its unique biosensor technology works with existing immuno, enzyme and DNA tests and it allows tests that traditionally take several hours of laboratory time to be performed in minutes. The universal biosensor platform technology, called Vantix™, can be adapted for applications in a range of sectors including medical, veterinary and environmental. Vantix™ opens up a new market opportunity for assay developers. It offers, for example, the potential for mobile screening of infectious diseases, or for enabling a vet or GP to perform a battery of tests in the surgery quickly and safely. Sensitive, fast and versatile – moving tests out of the laboratory. Universal Sensors Ltd is a Sensortec company.

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University College London - Biochemical Engineering www.ucl.ac.uk/biochemeng Biochemical Engineering, Gower Street, London WC1E 6BT

Extraordinary advances in the life sciences have great potential to improve our quality of life through better medicines and a cleaner environment. Biochemical Engineering provides the foundations for translating such exciting new discoveries into products and processes for improved health and wealth creation. At UCL, we offer education for undergraduates, postgraduates and industry professionals in our top-ranked department. Staff are engaged in cutting-edge research, both within the Department and as part of a number of European and international collaborations. In the 2008 Research Assessment Exercise 75% of Academic Staff were rated as “World Leading” or “Internationally Excellent”.

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University College London - Regenerative Medicine Bioprocessing

ACBE Roberts Building, Torrington Place, London WC1E 7JE

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University of East London Dr Richard Zheng r.zheng@uel.ac.uk www.uel.ac.uk Tel: 0208 223 2854

Dr Richard Zheng is the Director of Intellectual Property (IP) Development of the University of East London, covering a wide range of IP areas, including STEM, arts, and social sciences. UEL is one of the leading research institutions amongst modern universities according to the latest research assessment exercise. Its strong research profile has led to the generation of valuable IP, the exploitation of which benefits the economy, society and the scientific development of the world.

Room 2.24, Knowledge Dock Building, Docklands Campus, University of East London, University Way, London E16 2RD

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University of Essex The University of Essex, based at Wivenhoe Park, Colchester, received its Royal Charter in 1965. It is one of the UK’s leading academic institutions and has an international reputation for the quality of its research and teaching. The University has 19 departments spanning the Humanities, Social Sciences and Science and Engineering. There are currently around 8,800 students at the University, 25% of these within the Graduate School. The University is an international community with students from more than 125 countries. In recent assesments Essex has regularly ranked among the top 12 UK universities for the quality of its reseach and teaching, with many of its departments rated as ‘outstanding’ by international standards. Research Groups in Biological Sciences: Molecular Medicine Biophysics and Chemical Biology Marine Sciences Plant Productivity and Sustainable Agriculture Sports and Exercise Science The department has a unique research capability in the detection and imaging of ‘stress’ in biological systems in particular due to reactive oxygen species.. This expertise spans the molecular, cellular and whole organism levels and encompasses microbial, plant and mammalian systems. Research areas of biomedical interest include: GPCR structure and experimental biology Cancer, regulation of cell growth, biomarkers, cancer prevention and chemotherapy Diabetes and complications, advanced glycation end products (AGEs) Immunological receptors and recognition events Molecular biology of picorna viruses The department is equipped with state of the art facilities for cell and molecular biology, spectroscopy and biological imaging; and has pioneered the development of single particle fluorescence and other imaging techniques. In addition we have established multidisciplinary research groups Essex Biomedical Sciences Institute Centre for Systems Biology The Health Exercise and Active Life research Unit Centre for Environment & Society Coral Reef Research Unit.

www.onenucleus.com

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University of Reading www.reading.ac.uk

Tel: 0118 3788899

Harbourne Building, Whiteknights, Reading RG6 6AS

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University of Southampton

www.soton.ac.uk

University Road, Highfield, Southampton SO17 1BJ

Tel: 023 8059 8582

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University of Surrey Helen Ellis h.ellis@surrey.ac.uk

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www.surrey.ac.uk Tel: 01483 689063 The University of Surrey, Research and Enterprise Support, Senate House, Guildford, Surrey GU2 7XH

UroSens Ltd Dr Nick Miller-Jones

millerjones@urosens.com

Tel: 01223 836556 Mob: 0791 3801443

UroSens Ltd, Babraham Research Campus, Cambridge CB22 3AT

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www.urosens.com

UroSens develops rapid urine tests for prostate and bladder cancer. There is an urgent and unmet clinical need for cost-effective, non-invasive and accurate tests for these diseases. The widely used serum PSA test for prostate cancer gives a high rate of false positive results and therefore cannot be used in population screening. In bladder cancer, endoscopic examination is the current method of detection, which is invasive and expensive. Our test detects the protein Mcm5 in urine and is based on intellectual property in-licensed from Cancer Research Technology Ltd. Initial clinical work has demonstrated high accuracy for both indications.

Urszula Beckford Consulting urszula.beckford @googlemail.com Cleve, Seal Hollow Road, Sevenoaks TN13 3SH

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The University of Surrey has expertise in many areas of life science with key research themes in Cardiovascular Disease, Diabetes & Metabolism, Drug Design, Cancer, Toxicology, Infection and Immunity, Materials and Nanobiology, Sleep, Chronobiology, Neurological disorders, and Healthcare Practice and Well-Being. This also includes research into devices and diagnostics using novel biosensors and the development of enabling technologies for drug development. The Surrey Clinical Research Centre is part of the University and specialises in Phase 1 trials in sleep and CNS and has the ability to undertake Phase 1 to 4 trials in a wide range of areas.

One Nucleus Directory 2011

Consulting and interim management on technical aspects of in vitro diagnostics industry (design, transfer and manufacture of immunoassays and biologics).

UVP Ltd (Ultra-Violet Products Ltd) uvp@uvp.co.uk www.uvp.com Unit 1, Trinity Hall Farm Est, Nuffield Road, Cambridge CB4 1TG

UVP, established in 1932, is the global leader in life science imaging, supplying BioImaging Systems for academic, biopharmaceutical and biotechnology applications. With core expertise as the leading manufacturer of ultraviolet products, UVP combines its innovative technologies with a specialisation in fluorescent and luminescent-based imaging applications in the life sciences at the molecular, cellular, and whole organism life levels. UVP offers a wide range of BioImaging Systems from basic entry-level to advanced multifunctional systems for 1D and 2D gel documentation, chemiluminescent, fluorescent and colorimetric imaging plus fluorescent protein, small animal in vivo imaging. VisionWorks LS and VisionWorks 2D Software complement the BioImaging systems - combining powerful image capture capability with sophisticated analysis options. Ultraviolet Products cover a large selection of UV lamps, Transilluminators, PCR workstations, UV cabinets, UV intensity meters, UV Crosslinkers and UV incubator. Laboratory Products includes Hybridization ovens. Light Sources are configured with standard and custom designs.

www.veedacr.com Tel: 01738 850285 Fax: 01752 766933 Old Convent of Notre Dame, 119 Loosleigh Lane, Derriford, Plymouth PL6 5HH

Veeda Clinical Research is a full-service early phase global CRO with over 20 years of experience in phase 1/2a clinical research. Why Choose Veeda? Largest and most experienced Phase 1 CRO in India Phase I units in UK, India, Japan and Malaysia >700 studies completed to date >160 studies completed for USFDA submission 4 successful FDA audits and holds MHRA Phase I Supplementary Accreditation >180 analytical methods offered to date An established Biometrics team in Belgium and India Veeda Oncology is a global oncology CRO providing outstanding oncology expertise that the pharmaceutical and biotech companies require and expect to facilitate successful phase I to phase IV global programs. One of the few CROs whose focus is only Oncology. 77 Oncology trials conducted since 2001 at over 400 sites. Worked with over 440 investigators Access to over 110 ION sites in the United States. Screening possibilities of over 100,000 new patients a year. Exclusive relationships with several oncology hospitals in India which treat over 7,000 new oncology and hematology patients every year. Areas of Expertise include Diabetology including Glucose-Clamping CNS and Pain Women’s Health Renal-impairment Studies Cardiovascular Elderly Studies.

Executive Director Tel: 07725 312 567 First Floor, 165 Victoria Road, Alexandra Park, London N22 7XH United Kingdom

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Veltion Cell Therapeutics Ltd Tariq Osman

Veeda Clinical Research Ltd info@veedacr.com

Veltion Cell Therapeutics Limited (Veltion) is a biotech start-up founded in April 2010, headquartered in London. Veltion develops disease-modifying live cell therapeutics using allogeneic Mesenchymal Stem Cells (MSCs). Veltion combines a hybrid culture uniting pharma, biotech, and academia capabilities to create and deliver innovation using “pharma-ready” processes. Initially, the company aims to develop with its strategic partners novel medicines that leverage the potent fundamental attributes of MSCs (immunomodulation, cytoprotection and regeneration) in paediatric and adult patient populations. Specifically, the company targets autoimmune and inflammatory disorders, with an initial focus on gastro-intestinal diseases, GvHD, and cutaneous lesions resulting from radiation therapy.

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Venner Shipley LLP Dr Allie Elend mail@vennershipley.co.uk www.vennershipley.co.uk Tel: 01223 437979

Venner Shipley is one of the leading firms of European patent and trade mark attorneys. We have extensive experience of filing and prosecuting patent applications at the British and European Patent Offices, including post-grant opposition and appeal proceedings, and worldwide through our network of associates overseas. We also carry out infringement clearance work, prepare due diligence reports before launch of new products and organise litigation. We seek out the issues involved in order to understand the commercial objectives and achieve a successful, cost effective outcome.

Venner Shipley LLP, Byron House, Cambridge Business Park, Cowley Road, Cambridge CB4 0WZ

Tel: 020 7717 1560 90 London Road, London SE1 6LN

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Verdant Venture Management www.verdantvm.com

Verdant is a London-based company focused on developing start-up and early stage companies. Our experience has been gained mainly in the biotechnology sector, where we have worked with several companies in the UK, Sweden, Denmark and Switzerland. Among the services we offer are: Interim management Project management Non-executive directorship Financing Business development Partner search.

V W X Y Z

www.onenucleus.com

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Versant EuroVentures www.versanteuroventures.com

B C

Aeschenvorstadt 36, Basal CH-4051 Switzerland

D E F

Visionrt Ltd

www.visionrt.com

Dove House, Arcadia, London N3 2JU

VisionRT’s technology allows radiotherapy treatment to more effectively target the tumour site reducing damage to healthy tissue thereby improving outcomes, survival. It also can enable a reduction in the number of treatment fractions and minimise patient discomfort.

I J K L

W P Thompson and Co Simon Eddowes see@wpt.co.uk

M N O

www.wpt.co.uk Tel: 0207 240 2220

W. P. Thompson are a well established company of patent and trade mark agents. We have an international reputation for our expertise in all areas of intellectual property and we provide advice in all technical fields, including pharmaceuticals and biotechnology. We not only help our clients to obtain protection for, and defend, their own intellectual property but also help them to avoid infringement of third party rights. Our advice is tailored to our clients’ needs and we are well known for our commercial focus.

55 Drury Lane, London WC25SQ

P Q R S

Walker Graham Pharma Consulting info@walker-graham.com www.walker-graham.com 2 Park Farm Court, Carriage Drive, Clapham MK41 6EF

Walker Graham Pharma Consulting Ltd specialises in the provision of Qualified Person and Regulatory Affairs services to the pharmaceutical, medical device and healthcare sectors. Indira and Paul are two highly experienced qualified persons providing a range of QA and Regulatory solutions on a consultancy basis. They have current experience as QPs and RPs on IMP, Commercial and Wholesale Dealer’s Licences. Our services include: • Quality and Regulatory Consultation Services • Nomination as Qualified Person on manufacturers licence MIA, IMP and Responsible Person on wholesaler licence • GMP and GDP auditing • Quality Risk Management

U V

Wallder Capital Limited David Wallder

W X Y

Tel: 07887 540 035 Vectis House, 7 Nightingale Lane, St Albans, Hertfordshire AL1 1DX

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One Nucleus Directory 2011

Wallder Capital Limited - Investors in early stage life science companies.

Wangi Ltd 16 The Atrium, 30 Vincent Square, London SW1P 2NW

A Corporate finance: capital raisings, IPOs, M&A, in/out-licensing, due diligence, valuations; Wealth manager; Investor relations; Management consulting: corporate strategy, business and marketing plans, restructuring.

B C D E F

Warwick Effect Polymers Ltd Dr Jill Ogden jill.ogden@wep-ltd.co.uk www.wep-ltd.co.uk Tel: 0247 669 2476

Warwick Effect Polymers (WEP) specialises in novel technologies to enhance biological and small molecule therapeutics. WEP has two proprietary technologies: GlycoPol™, an innovative glycopolymer-based drug targeting and delivery technology and PolyPEG®, a next generation PEGylation technology for half-life extension based on very low viscosity polymers. The company’s objective is to develop partnerships with third parties to produce GlycoPol™ and PolyPEG® enhanced therapeutics.

Vanguard Centre, Sir William Lyons Rd, University of Warwick Science Park, Coventry CV4 7EZ

Tel: 01223 494714 Wellcome Trust Genome Campus, Hinxton, Cambridge CH10 1SA

H I J K

Wellcome Trust Sanger Institute www.sanger.ac.uk

Our research at the Wellcome Trust Sanger Institute builds understanding of gene function in health and disease as well as creating resources of lasting value to biomedical research. We study diseases that have an impact on health globally by investigating genomes. Building on our past achievements and based on priorities that exploit the unique expertise of our Faculty of researchers, we will lead global efforts to understand the biology of genomes. We are convinced of the importance of making this research available and accessible for all audiences.

L M N O P

WOCP

info@wop.org www.wocp.org

12 Grange Avenue, Cambridge PE1 4HH

S T U V W X Y Z www.onenucleus.com

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Notes

156

One Nucleus Directory 2011

Advertisers Index Alpha Biologicals

Mangement Forum

AMS Biotechnology Europe

Mathys Squire LLP

Ascot International (1996 Ltd)

Melbourn Scientific Ltd

Babraham Bioscience Tech. 142 & 160

MEPC Granta Park

Beckman Coulter Genomics

Mircon Research

NeuroSolutions Ltd

Bio Nano Consulting Ltd

54 & 159

Bioannalytical Systems Ltd

PAA/VQ-SET

Biocair International Ltd

Parker Dominic Hunter

Bridge Partners

Pharma Matrix UK

Bridgehead International Ltd

Pharmidex Pharma Services

Briton EMS Ltd

Popharma Partners Ltd

Cambridge Research Biochemicals 17

Potter Clarkson LLP

Cambridge Science Park

Protein Tech Europe Ltd

- Trinity College

158

One Nucleus Directory 2011

Q Chip Ltd

Carter Jonas

Queen Mary Bio Enterprises Ltd

Delta Consultants

Raumedic UK Ltd

RSA

Distinctive Publishing

40 & 60

Double Tree by Hilton

RWS Group - Medical Translation

Dr Reddyâ&#x20AC;&#x2122;s Laboratories (EU) Ltd

Safety Information Services Ltd

Eagle Genomics Ltd

Science Warehouse

Eurosolve Ltd

Starlab UK Ltd

Forest Heath District Council

S-Tech Insurance Services

Forresters

Sygnature CSL

Harten Group Ltd

Synapse Clinical Research

Health and Safety Works Ltd

Team Consulting Ltd

Heptares Therapeutics Ltd

Thermo Fisher Scientific

Jag Express

Twist DX Ltd

Jenkins and Jenkins

University of Sheffield

Kelly Services

Verius Ltd

Kershaw Technology Services

Vivos Technology Ltd

London Associates

3 157