Rising Tide 2017

RESEARCH AND SCHOLARSHIP AT THE UNIVERSITY OF NEW ENGLAND 2017

Outcomes are equally important when evaluating the growth of research and scholarship (R&S) at UNE, as these efforts are featured prominently in UNE's strategic plan and have received significant investments of both internal and external resources.

The conclusion of UN E's Vision 2017 strategic plan, as well as preparations for upcoming accreditation visits, have provided plenty of quantitative data indicating the progress we have made. Over the past 10 fiscal years, UNE has seen a 325 percent increase in R&S expenditures provided by external sponsors.

We rank first in NIH funding for the state of Maine for colleges and universities! UNE currently has 97 faculty and staff who are receiving active funding, representing a 7.7 percent increase from the last fiscal year. There has also been a correspondingly robust increase in peer-reviewed articles (225 percent over the past 10 years) as indexed in the Scopus data base.

But these numbers, as impressive as they are, only tell part of the R&S success story taking place at As I write this introduction in the first week of November, outcomes are front and center. From the World Series (congratulations, Chicago Cubs!), to the Election and everything in between - including this edition of Rising Tide magazine.

UNE. The number ofonline stories highlighting the R&S accomplishments of our faculty and students continues to increase and makes up well over 50 percent of new content found on UNE websites.

Through the efforts of the UNE Communications

Getting some inspiration while attending fall playoff games for UN E's successful athletic programs, I was reminded that sporting events generate some of the most definitive outcomes that can be tracked and assessed, including win-loss records, conference championships and the multitude of individual and team statistics that are constantly updated and pored over by athletic directors, fans and parents alike.

While these stats are important in tracking progress and performance, they do not tell the entire story. There are also the qualitative elements of education and the maturation that occurs over the student-athlete's tenure at the university, facilitated and guided by the coaching staff and others: the wisdom gained by experiencing wins and losses, the satisfactions of engaging in teamwork and successful goal setting, and the discipline of making a commitment to preparation - and then delivering a performance into which you have put all your effort.

Members of the new UN E women's varsity rugby team square off against their Harvard counterparts

department, these stories are appearing with increasing frequency in local, state and national news and print media outlets, expanding the visibility of our quality academic programs and attracting a broader pool of prospective students. These written and visual narratives fill in the who, what, where and why behind our R&S initiatives, giving faces and voices to the important work we are conducting, There is more work to be done as we assess the impact that our R&S efforts are having: on the education of our students, on our respective disciplines, and in addressing some of society's most pressing issues. One of the challenges is in categorizing a student as a scholar. For athletics, categorization is clear: a student is either on a varsity team or is not or participates in an intramural activity or does not For research and scholarship, what constitutes the minimum threshold for a meaningful experience?

Are there differences in how we classify undergraduates versus how we classify graduate or professiona I students? We also need to think of creative ways to accurately track students who are engaged in R&S endeavors, internships and community service-based projects that contain a scholarly component.

The featured stories, snapshots and profiles contained in this issue of Rising Tide help fill in the space between the quantitative and the qualitative, looking at the past six months of research and scholarship at UNE and providing it with the light, color and warmth of narrative. I can't help but be drawn into these stories. Then, taking a step or two back, I look across the broader scholarly landscape

We have encouraging preliminary data suggesting

and see how well integrated R&S has become with

that providing authentic R&S experiences increases

UNE - with our culture and our mission. It's a

student retention and academic performance - an

breathtaking achievement, and I am very fortunate

effect that is similar to what we see with student

to have worked with so many talented faculty, staff

athletes. From national student surveys we know

and students in helping create something so robust

that UNE undergraduates enter their academic

and meaningful. And that, surely, is an outcome of

programs with higher expectations of conducting

which we can all be proud.

R&S than their non-UNE peers. Exit surveys of UNE seniors indicate that UNE students do, in fact, conduct R&S at rates significantly higher than undergraduates at peer institutions and private colleges and universities in the New England region.

~ KY VICE PRESIDENT FOR RESEARCH AND SCHOLARSHIP

As you know, running and life become deeply intertwined, and this sport can be a great vehicle for inspiring greatness in other areas.

- Will Fulford

Will Fulford

To give anything less than your best is to sacrifice the gift.

One of Will Fulford 's favorite quotes, from legendary Olympic runner Steve Prefontaine.

This year's Rising Tide magazine is dedicated to the memory and legacy of Will Fulford, who passed away unexpectedly at the age of 29 while exercising with

One thing Will told me that has stuck with me is, 'One of the million ways running is like life is that you have to keep going, and it always gets better.' This past fall, with Will's training, my teammate Annelise and I ran a marathon and qualified for Boston, a life goal for both of us. Before the race we dedicated each mile of the race to someone important in our lives that had gotten us to that race ••• Will got mile 26.

- Taxia Arabatzis (M.S. in Biological Sciences, '17)

his wife, Ashley Potvin-Fulford. Will was the assistant coach to the UNE men's and women's cross country teams, as well as the head coach for cross country and track at Biddeford High School. He also helped start UNE's Track and Field Club and was always willing to offer his services when it came to running-related technique and form, offering sessions on running at the UNE All Sports Camp and the Girls Got Game camp.

Will had an enormous positive impact on countless

Will was the type of coach who believed in you even when you didn't believe in yourself. He inspired all of his athletes, myself included, to push ourselves more than we realized we could. This helped me find success not only in running but in other aspects of my life as well.

- Stephanie Ostrowski (Applied Exercise Science, '17)

young student athletes in the UNE and Biddeford communities, including my own sons, Jacob and Joshua, who ran for him at Biddeford. He was a quiet and humble man who was particularly effective in building athletes' confidence in themselves, instilling an admirable work ethic and inspiring a full and heartfelt commitment to the team.

I had the privilege of having Will as a coach for my four years at UNE, and he was one of the best and most dedicated coaches I've ever had. I wouldn't be the runner or the person I am today if it wasn't for Will.

- Brittney Sorbello (COP, ' 19)

Several UNE runners were also engaged in research and scholarship at UNE, and we asked them to share brief personal remembrances of the man they admired who had so profoundly affected their lives. The tribute that moved me the most was spoken by his grieving mother as she remembered Will and asked us to honor him by being gentle, kind and caring and by giving 100 percent to everything we do.

You will be missed, Will, but never forgotten.

~

Will was a quality-over-quantity guy when it came to his words. I had never met a coach who could change my entire mindset in two sentences until he came along. We all agreed we could hear his voice in our heads during races saying what he would always say to us: 'You're fine.' And that was just it, we were fine. Will knew the workouts to make us physically stronger, but, more importantly, he knew what to say to help us become mentally stronger. And for that, he will never be forgotten.

- Erin Edwards (Neuroscience, '15)

COLLEGE of ARTS and SCIENCES Small Fish Bring Big Opportunities to UNE

a 9

Research Experience a Factor in UNE Undergraduate Student Success

13

Digital Initiatives Prepare Students to Embrace the Future

14

The Role of Food Security in Public Health and Community Sustainability in the Year-Round Islands of Maine

15

Invasion of an Aggressive Crab

17

UN E's First Artist-In-Residence Moves Students Forward

19

Interview with Alex Campbell: UN E's Only Philosophy Major

21

The Digital Promise: Reshaping Teaching and Learning via Student Engagement to Improve Success and Retention 21 UNE Marine Science Center Acquires Two New Research Vessels

22

COLLEGE of OSTEOPATHIC MEDICINE

24

WADEM seeks Collaboration with UNE

25

Rapid Evolution of Zika Virus and its Study

27

Oh! The Places You'll Go! One Path to Research and Scholarship

29

COM Faculty Making Neuroscience Lesson Real and Fun

31

Student Research in the Mokler Lab at UNE

33

Bridging Critical Care and Neurology for Survivors of Cardiac Arrest

35

Up and Coming Researcher: Student Doctor Mark Unger

35

WESTBROOK COLLEGE of HEALTH PROFESSIONS

3a

Chronic Pain, Motor Output and Motor Learning in Knee Osteoarthritis

39

Supporting Adolescent Adherence in Vietnam

42

Assessing Carotid Artery Changes in Children in the Cardiovascular Health Intervention Program (CHIP)

43

The Cho Ro Test of Visual Perception Related to Driving

44

Supermarket Science: Multipronged Approaches to Increasing Fresh, Frozen and Canned Fruit and Vegetable Purchases

45

Introducing IHS 130: Health Profession First-Year Experience!

47

Learning Together for Future Practice Together

47

lnterprofessional Research Collaborations to Improve Outcomes in Athletes Post-ACL Reconstruction

49

Identification of Academically At-Risk Accelerated Bachelor of Science in Nursing Students to Support Development of Strategies to Promote Academic Success

51

UNE Researchers Investigate Head Impacts in Men's Lacrosse and Men's and Women's Ice Hockey

51

Self-Organizing Sensory Strategies Promote Occupational Performance

52

Outcomes a World Away!

52

The Maine Leadership Education in Neurodevelopmental Disabilities (LEND) Program: Making a Difference for Children and Families in the State of Maine

53

Screening Graduate School Applicants for Emotional Intelligence

54

Changes in Hydration Status during Pre-Season Training

55

Increasing the Public Health Nursing Workforce

55

5 I RISING TIDE

COLLEGE of PHARMACY

sa

UNE Student Involvement in the Scholarship of K-12 Educational Outreach

59

Tackling the Crisis of Antimicrobial Resistance

63

Student Perceptions about Mental Illness: Looking into Student Attitudes, Disclosure and Inherent Stigma

65

Alumnae Spotlight - Student Researchers Find Success in the Pharmaceutical Industry

67

Novel Prognostic Marker for Aggressive Breast Cancer

69

Molecular Determinants of Drug Resistance

69

Determining Whether Plastic Nanoparticles Change the Impact and Transport of Benzo[a]pyrene (B[a]P)

70

Investigation of Antifungal Activities of Polyalthic Acid Derivatives

70

COLLEGE of DENTAL MEDICINE

12

UNE CDM Students Rotate Through Dental Clinic at Portland High School

73

CENTERS of EXCELLENCE

1,

Outcomes Emerging from the Center for the Enrichment of Teaching and Learning (CETL)

77

Identification and Intervention for Students "At Risk" in Osteopathic Medical Knowledge

78

Utilizing Engagement-Oriented Teaching Strategies to Create More Dynamic Learning Experiences

79

Using Digital Technology to Improve Teaching and Learning Outcomes in Anatomy Courses

81

Assessing Curricular Reinforcement of Pharmacy Compounding Skills

83

Researching the Environment in Active Learning Spaces (REALS): Are There Impacts on Instruction, Student Engagement and Learning?

84

Center Support Yields Collaborations Between Neuroscientists

85

Providing the Groundwork for Future Careers in Neuroscience

87

A Career in Neuroscience

89

UNE Continues its Effort in Training PhD. Students in Biomedical Sciences

90

Maine Festival-Goers Greeted by Neuroscience Volunteers

91

Buzzing with Neuroscience Enthusiasm

92

lnterprofessional Team Immersion for Health Professions Students: Making It Real

93

Makerspace Technical and Project Specialist

95

Collaborating to Connect Health Care, Public Health and Education

97

RESEARCH and SCHOLARSHIP

100

Pain Awareness and National Recovery Month Pulls Communities Together

101

UNE's 2016 Brain, Body and Wellness Fair a Big Hit with Students and Families

105

Pain Summit at UNE

107

STUDENT SNAPSHOTS

109

RISINGTIDE I 6

Small Fish Bring Big Opportunities to UNE DEENA SMALL, PH.D.,ASSOCIATE PROFESSOR, COLLEGE OF ARTS AND SCIENCES J ERI FOX, PH.D., ASSOCIATE PROFESSOR, COLLEGE OF ARTS AND SCIENCES ~ AREl:-l_H_O USEKN.ECJ:il,21:Lfa,RROÂŁ E_S_S_O_&, C_O L_LEG_E OE._O_S_I_E02AD::LLC_M E.DJClliE.- - - - - - -

TEACHI NG. RE SEARCH. ENTREPRENEUR SHIP. OUTREACH. The goal of the UNE Zebrafish Educatbn and Research Fa: ility is to pre>1ide UN E faculty, staff and students with opp:,rtunities to pursue these essential UN Emissions. The eftbrtto establish the facility beg,,n after Doena J. Small, Ph.D., associate professor of chemistryand ph}'Sics,attended a taxtologyconference where scientists from all over the world were presentingdatathat used zebrafish as a model S'YStem.

I realized how useful zebrafish would be for not only reseaix:h but also as a hands-on leaming tool for students taking courses in a wide range of disciplines.

- Deena Smal I "I was amazed at the abilitytovisualize effects of chemicals and pharmaceuticals on cell ty~s and tissues in the embr~n t and adultflsh,''said Small.

"I realized how useful zebrafish would be for not only research butalsoas a hands-on earn ingtool for students takingcourses in a wide range ofd isciplines.''

Small soon identified faculty and staff from both the COiiege of Arts and Sciences (CAS) and the College of Osteopathic Medicine (COM)who had knowledge about the zebrafish model and were e>eited to establish a fa: ilityat UNE.A committee was formed, including Small; Jeri Fa<, Ph.D., professor of biology and marine sciences; Karen Houseknecht, Ph.D., professor of biomedical sciences; Megan Beauchemin, Ph.D., p:istdoctoral fellow in bbmed ical sciences; and Za:hary Miller-Hope, M.S., lecturer in biology. The committee's goals were toconducta feasibilitystudy, find spa:e for the facility, and seekfunds tofl nance the initiative. The grou pwas thrilled when CAS Dean Jeanne HeY, Ph.D., COM Dean Jane Carreiro, 0.0., and Vice President 1br Research and Scholarship Edward Bilsky, Ph.D., offered theirenth usiastic supp:,rt.

David Mokler, Ph.D., chairof the D,partment of Biomedical Sciences (COM),explained, "The COM dean and I supported the zebrafish facility because of the need to continually invest in our research

infrastructure with the latest science in order to supp:,rtthe research of our fa:u lty." CAS Associate Dean David Guay, M.S.,echoed this sentimentand remarked,"The establishment of a facility1bra new mo::lel organism will have a lasting im pa:t on the

universityfor decades."

c:,...n Tumer Q).q.iaillrn Sdence .n:I Maine Sden::e. '1 7)piw.res tie miaoirjeO:Or ~ loadngtie ~pette Y,Uh 1is:s1Jestain.

91 collegeofartsandsciences I RISINGTIOE

,, MEGAN BEAUCHEMIN, PH.D., POSTDOCTORAL FELLOW, COLLEGE 0 ~ OSTEOPATHIC MEDICI NB ZACHARY Ml LLER-HOPE, M.S., LECTURER, MARINE SCI ENCE TECHNICIAN \ . - - - - - - - - - - - - - - - - - - - - - - - sC_QLLEf; E 0£.ARISAND S_C_LE/'LCES

Desert Island Biological Labora1ory(MDI BL) in SalisburyCove, Maine, which she says "will elucidate the developmental pharmacologyu nderlying mco::1 disorders, includ ingADH D, using genetic, behavbral and pharmacologyapproa:hes in zebrafish:' Both Small and Fax also are workingon environmental 1D<icobgystudies with facu ltyfrom UMaine, M DIBL, Smith College and UM ass.

Zebrafish serve as an important model for studying human disease, as they share over lhe UN Ezetfa!im Edl£alion .n:I ResM'Ch F'adlitytearn ~rn left 1:0 tigh~ ~.v'l ~chertin, Fh D.. i<:.nn 1-bllSEIGlecht, Fh.D., Deula.lSmal, FhD.,JEr1 Rrx, FhD.,.n:1 Iadl<f'Y MillEr•l-bpe, MS.

70 percent genetic similarity with humans.

WHY USE ZEBRAflSH FOR RESEARCH? The zebraflsh, Donio rerio, is a small,striP3d, tropical minnow originally1bu nd in South Asia. The zebrafish has gained acceptance as a vertebrate mo::lel system in more than 11,100 laboratories and companies worldwide. Meg,,n Beauchemin, Ph.D., UNE p:,stxloc1oral fellow in the COiiege of Osteopath i: Medicine,explained, "Zebrafish serve as an imp:,rtant mo::lel for studying human disease, as theyshare ooer

- Megan Beauchemin

Meanwhile, Kerry Tucker, Ph.D.,asscc iate professor of biomedical sciences, plans to use zebrafish to study diseases caused by defects in ciliaorganelles

70 P3rcentgenetC similaritywith humans.Zebraflsh

are utilized in all asP3cts of biomedical research, includingdevebpment, re~neration, infectbus disease,cancer and toxicology.Advantages include amenabilityto genetic manipulatbn, costeffectWeness and rapid embryonic development. It is no wonder

8.

that these amazingcreatures have earned their rightful place in the wortl of biomedical research."

The establishment of a facility for a new model org-anism will have a lasting impact on the university for decades- David Guay

Several UNE facu ltymem bers are alreadyengaged in collatorations on a variety of projects. House knee ht is cond uctinga study with scientistsatthe Mount

C.

lhe de.elcpmEntal ~ s Of 2etnflm .re mcmn t'crn f'le liM tieeg:gs .re ~nilized Ullil tley read'l f'le jlM!f'lile St.¢e A. Iebratam b1~1a at tie 64ceil St.¢e. B. la'...al 10trn ota gEnelicallyen&in&nd zEb'a!lsh llSed 1:0 deted tie rn~aisrn Of en...irmMnY dYSl'licais sldl as diOion, <.

L<f'l.lal zeb'atash e.pres:si"' a green 11.Jct'esO?nt p-otein in n8J1t0pil cells otf'le inrnU'le ¥tin.

RISING TIDE

I college oh rtsand sciences I 10

~a 9.IStaoe Q).qllaiUll Sden::e,'1 7)t.b:s readirts en water q.i<11ityp.r.rnetErS f'crn wiks tlatoo~na wain Of:ebratam tlat1llletesoe 1,,pcn e:.posU'e 1:0 en...in:nnw?nt.11 end:laine disr1,,p~rs (EEDs)

that are imp:,rtantfor cellular motilityand resp:,nse toenviron mental cues.Joseph Kunkel, Ph.D., research professorofmarine sciences, will examine zebraflsh scales tostudybone met:atolism and osteop:,rosis using his lab's non-invasive ion protes.

All ofthese projects are expected to include student researchers,albwingstudents to gain desirable skills that are attra:tive foremploymentand graduate programs. Once established, the nu mterof facility users is exP3cted to grow as word spreads a tout the teneflts, including low cost, of this mo::lel organism.

ZEBRAflSHASAN EXPERIENTIAL LEARNING TOOL Zebraflsh are an easilyaccessible, inexP3nsive hands-on tool foreducatbn. UN Efacultyteaching in diverse disciplines sue has biology, chemistry, environmental science, marine science and neurosc ience can devebp innovatWe P3dagogies with zebrafish that sparkstudent interest. Students enrolled in the Aquaculture and Aquarium Science program in the Dep:artmentof Marine Sc enc es will clearly benefit from the facility, as Fa<, the program~

11 I collegeofartsandsciences I RISINGTIOE

director, explained. "UN E has one ofthe only a::i uarium science programs in the northeast,'' Fax said, "but until now, students' exP3riences were pri ma ri ly Ii mited to fco::I organ is ms and or nam en tals.

Although the program has been successful at p:,st-grad uatbn placement, the addition of the zebraflsh will augmentexperiences preparing students for employment in the growing number of zebraflsh centers associated with research hospitals, universites and businesses."

UNE has one of the only :aquarium science progmms in the northeast [...] the addition of the zebrafish will augment experiences preparing students for employment in the growing number of zebrafish centers associated with research hospitals, universities and businesses.

- Jeri Fox

I look forward to this exciting new science education - Deb Landry opportunity..

De to rah DuDevoir, Ph.D.,asscciate lecturer of biology,and Jess Wheeler, M.S., biology lal:ora1ory assistant, have already planned genetics courses such as Fish Geneti:s (BIO 205) in which students breed and examine zebraflsh embr~s to study Mendelian gen et Cs and chromosomal inheritance.

Finally,as part of UN E's outreach mission, zebraflsh will te accessible to local schools and other educational organizations in the community. For eo<ampe, D,b Landry, Ph.D., founder ofiXplore STEM, plans to incorp:,rate U NE zebraflsh into hersummer science program. "I bokforward to this e:xc iting new science education opp:,rtunity," Landrysaid.

ZEBRAflSH ASAN OPPORTUNITY FOR ENTREPRENEURSHIP The UNE zebrafish 1'1cilltywill also lend itself 1o biotech nologyand a::iua:u lture initiatives with local business partners. UN Eand the Fish Vet Group in Portland, Maine, have already signed an agreement for student internships. Discussions are also underway with this companyand others regarding collatorative projects on a::i uarium design and the de.elopmentofspecialtyfeeds.AnthonySantella,

MA., assistant lecturer of business and UN E Ma~rspace coordina1or, is e>eited that the t,,c ility can te used as a resource tosupp:,rtentrepreneurship initiated by UNE facultyand students who may te fee used on the biotech nologyand a::iua:u lture sec1ors. He thinks th is work may i:otentiallyopen new revenue streams thatsupp:,rt UNE programs.

Given the diversity of potential applications, these smrul fish will indeed bring big opportunities for teaching, research, entrepreneurship and outreach to UNE. The U NE Zebrafish Education and Research Facility is exP3cted tote the onlyfull-service facilityin the southern Maine and coastal New Hampshire area.

UNE P3rsonnel may use fa:ilityservices for nominal fees. User fees will also te generated from eel ucators, scentists and businesses interested in using zebraflsh in their classrooms, latoratories and businesses. The facility is eo<pected 1o be open bysummer 2017 and will offer workshops on research tee hniques and P3dagogyover the upcoming~ear. Given the diversity of p:,tential applications, these small fish will indeed bring bigopp:,rtunities for teaching, research, entrepreneurshipand outreach to UNE. •

lhe Aq!Slewi"', he. .o.q..wiasystern ~ 'MIi l'ollSe lP 1:0 7(XJ'J :Eb'atim "Mfin tie UN£ ?Eb'atish £d.icalicn .nd Ae:sffd'l ~lity 'MIi be located in MCl'g.ne ~I en tie Eliddetln:I <.np.Js. 1he e::$1ity 'MIi <11soprodJceawcwN1W?1y2(XJ'J:ebratishernl:t',.osper~.ndOffer seNoes ind1.1dng tie prodldon Of 11.nsgg-iictam.

RISINCTIDE I collegeofartsandsciences I 12

Research Experience a Factor in UNE Undergraduate Student Success GLENN W. STEVENSON. PH.D .. ASSOCIATE PROFESSOR. DEPARTMENT OF PSYCHOLOGY RRQGRAM.LQDRDI t-lAIOR, t-l EUROSC.IEt-1.C.E MAJOR,- - - - - - - - - - - - - - - -

A question we hear frequenttyfrom prospective students and theirfam ilies as theyshopfor colle~ is, 'Where do ~u r graduates end up?"There are many

variables that impact pla:ement for college gra:luates, includingthe amount of hands-on research exP3rience a graduate has. One salientfac1or at U NE is the opp:,rtu nity undergraduates ha11e 1ov.ork s ae-by-side with facultyin their research labs. The growth in STEM disciplines at UNE, includ ingthe interdisciplinary

neuroscience ma.Pr, has resulted in recruitmentand retentbn of nationally- and internatbnally-recognizd

fa: ultyand, imp:,rtantly, the attra:tion and retention oftop-ter students to our campus.

The behauioral pharma:obgy lal:ora1oryof Glenn Ste11enson, Ph.D.,asso: iate professor of ps}Chobgy, is but one eo<ample of dozens of U NE t..culty research lal:orator es that em ploy undergraduates tude nts with a primarymissbn of trainingthem to think and P3rform as sc entists. Students in the Stevenson Lab run all exP3riments, do all data recording,anatysis and interpretation, write software co::le to run equipment, take part in plann ingfuture directions, present data at national and international meetings,and serve as Cljauthors on peer-reviewed published journal

Cone, B.S. '15 (Neuroscience); Rebecca Krivitsky, B.S. '16 (Neuroscience); and Emily Warner, B.S. '16 (Neuroscience).

articles. Stevenson promotes one junior ea: h year to

Atherton currentlyserves as an RN at Newark-

serve as tab mana~r,and this student eadsall projects and is resp:,nsible fort he daily runn ingof the lab

Wayne Community Hosp Ital in upstate New York.

Cone isa ft rst-}ear student in the UNE College of

- a resp:,nsibilitytypically reserved for graduate or p:,stdoctoral students at most institutions. Students

student in the Doc1or of Op1ometry program at No,-a

Osteopathic Medicine. Krivitsky is a fl rst-year

typcallyj:)in the labasfreshmen or sophomores and stay

Southeastern Un Wersity, and Warner is a flrst-~ear

until gra::I uation. Since the Stevenson Lab was started

student in the Ph.D. program in neuroscience at the

11 years ago, its graduates ha11e had a 100 percent

Uni11ersltyof Rochester School of Medicine.

success rate for graduate school and job placement.

Asamplingofolder alumni includes Amy Luginbuhl, The student lab experience is not limited to the

B.S. '11,currentlyan RN at Brigham and Women's

UN E campus,as the Ste11enson Labcollal:orates with

Hospital in Bos1on; Laura Benoit, B.S. '10, currentlya DY.M. in private practice; and Jim Corm er, B.S. '09,

other research facilities, includingones at Harvard Medical School, the Universityof Aria:ina, Virginia

who sP3ntseveral ~ears in the biotech sectorand is

Commonwealth Universityand the Maine Medical

currentlya second-}ear student in UN E's College of

Center Research Institute. These collatorations

Dental Medicine.

provide ourstudents with a:cess to other eaders in the sciences and, in some cases, an intro:! uction toa future gra:luate school mentor.

Stevenson believes that the combination of hands~n exP3riential research opp:,rtunities, a:tive learning in the classroom, world-classfacultyand supp:,rtive

Recent examples of students who exP3rienced

a:I ministratbn,and the unwaveringstudentcu riosity

successful outcomes afterworkingin this latoratory:

and work ethic synergize to result in the successful

Philip Ather1on, B.S. '15 (Nursing); Katherine

pla:ement of our students. â&#x20AC;˘

13 I coHegeofartsandsciences I RISINGTIOE

,, Digital Initiatives Prepare Students to Embrace the Futur~ JESSE MILLER, M.F.A., VI SITING ASSISTANT LECTURER . . . c . . - - - - - -MtCl:IAELCRli:>12.S, i:>1:1.D., AS.SOCIATE i:>ROEES.SDR_DF. Rl:I EJ_DRICAI\I D COM!:>0.SJIIOI\I

Preparingstudent:s <orthewortl after colle~ is among the mostimp:,rtantcanp:,nent:s ofan edu:atbn.

However, with an unknowable future, how will students be best prepared? The Colle~ of Arts and Sciences (CAS) recognizes that a fac ilitywlth digltal tools must

te in the mix. Since '.X:l13, with financial assistancefrom the Dau is Educational Foundation, 11 CAS t..culty members have participated in a semester-longseminar todevelopdigital projects in their courses. New this }'ear, CAS has launched ad igital makers pace and an eo<panded electronic portfolio ~Portfolio) in ltiative tosupp:,rtand extend existingwork in new directions to help students embrace the digital.

The ePortfolb initiati'le, UNE Portfolios, is a web space for students toe raft aspects of their digital identltes.

Launched in 2012as asetofsmall,course-based pilots in the English department, UNE Portfolios now has a domain name and serversupp:,rtto help it grow. Since

Vl\fl its 2& Macbook Pros. llis oobile lffling iab can ao::onrno&te a fUI das:s ots11.den1S as fleyblild flEir digital iden1i1ies at tie c:-g;spaoe.

OigiSpace is more than a computer lab. With fmanc ial support from the CAS Dean, the English department and the Davis Educational Foundatbn, the OigiSpace assists students with ePortfoliowork, cours&based video projects and more. Hund reds of students are engaged in digital work in CAS, making the DigiSpace an imp:,rtant resource.

September 2016, nearly 150first-}Oarstudents haue tegun ePortfoliowork. Byinclud ing projects assigned

Associate Professor of Spanish and Portuguese Ste'len B}'ld, Ph.D.,a recentdigltal literacyseminar parti:ipant, explained how his classes embrace the digital, saying, "In my previous Spanish classes, students wrote and

in a varietyofc lasses, as well as their own creative work,student:s can use ePortfolios to curate a to:ly of digital work over time. Eventually,students will use their ePortfolbs to showcase their learningand professionalism as theyapplytograduate programs

P3rformed scripted scenes live in the classroom.

These, typically, tecame just a live readingoftheir dialogues,and the only effort was put into the written text Now, with their digitalvtleo projects, students are spending more time on their scripts and

or prepare toenterthe workforce.

rehearsingtheird ialogues much more before they record and present them to the class.''

Jesse Miller, M.FA., visitingassistant lecturerand OigiSpace Labcoordinator,oversees all asp:cts ofthe new Mac-based digital ma~rspace called 1he DigiSpace.

Staffed with peer Digital LiteracyConsultants, the

Enth us ias m for the OigiS pace and e Portfolio is not ju st limited to faculty. Sandy Pham (Elementary Education, '20), working on a project for her Introduction to the Humanities class, raved, "I wenttothe OigiSpace and itwassoteneflcial! I'm glad lwent-1 think my ePortfolio looks awesome now!"

Miranda Hall (Ps}Chology, '19),a digltal literacy consultant, assisted Pham with her project. Hall, who boles helpingstudents with digitaltoo~. noted, '1 haue wor~d with students recordingsP3echesand on their ePortfolios. I am eo<cited fora class that isgoingto be using [the audioapplication] Auda:ityto 'vOiceovera Prezi [the web-based presentation application]!"

Although the future is unknowable, creating opp:,rtunities for students to gain fa:ilitywith an ever-increasingdigital tool tax may te the best way toensure theyare prepared to meet whatever tomorrow has to offer. a RISING TIDE I COIi~ ofa rtsand scieoces I 14

he Role of Food Security in Public Health and Community Sustainability in the Year-Round Islands of Maine.- - - - - - - - - - - - - - - -

Maine has teen called the pla:e whereAmerica reallybeg,,n (Caldwell, 2001). If Maine is where America tegan, then its fl rstcommunities were on the islands of Maine. These islands ha11e played and continue to playac ritical role in the history, economy, environment and social life of the state.

The nature of th is role and of these communities, however, is changing. Prevbus efforts on my part have fee used on the role of com mu nitysustainability in the year-round islands of Maine (Mc Reynolds, X:.14). Duringmyearlier research (Mc Reyno tis, 1997) it was evident that food availabilityand the costof1tod on the islands were growingconcerns.

Prices offco:I were, on average, 31 P3rcent higher on the islands. Furthermore, manyfco:ls were simply not regularlyavailable, such as fresh ve~tables and

meats (McReynolds, 2014).

Parallel to myworkon the islands was a growing to:lyofliterature thatexamined the imp:,rtance of

15 I collegeofartsandsciences I RISINGTIOE

foo::I security in economic and social devebpment (Swaminathan, 2001; Pothu loochi, 2004). More recently, literature has teen emergingon how to measure 1'co::I insecurityand its relatbnshipto de11elopment (Barrett, 2010). Th is work, however, has largely teen appled to developing nations and island communities in Asia, while little, if any, such work has teen done on island communities in the United States. Although housing (Satsangi, 2009) and jobs (Mc Reynolds, 2104) remain at the core of sustainability, fco:I is agrowingand often overloo~d elementof commun itydevelopment (Brocklesby and Fisher, 2003).

Preliminary results from the research ind Cate that island food prices relative to the mainland have fallen to 24 P3rcent indifference and that many islands have found new and c reatWe ways to cope with 1'co::I issues. Still, probe ms ofavailabilityand security remain. SP3ciflcally, the precarbus nature of island stores remains a central issue to island life.

,, SAMUEL A. MCREYNOLDS, PH.D., PROFESSOR, SOCIOLOGY CHAIR, DEPARTMENT OF SOCIETY CULTURE AND LANGUAGES ..__ _ _ _ _ _ _ _ _ _ _ _ ___.,D,,_1Rs,: ,,_EC ,,,,T uO ...,,, R, 0 FICE OF. CITIZENSHI P. AND CIV C ENGAGE E

More imp:,rtantlY, however, this research has raised imp:,rtant issues ofpublt health in island sustainability.

P3rcentofresp:,ndent:s telieved there were sufficient

Our intervews ~eld otherareas in need of further exploration. For example, the incidence ofd iseases, such as cancer, thatapP3ar to tewell atove state and national norms was noted. The next step is to obtain

resources for teal th ca re on the island, wh ie 44 P3rcent

theepidemiobgtal datatodetermine ifthese anecdotal

disagreed orstronglydisagreed with this conclusion.

incidents sP3aktoa greater health concern. •

For exam pie, our surveyind tated thatfewerthan 3:)

onmostiSl.rds.tlegrocevs-=,resd:lrotM\'ehs-=,r.¢ec.Jladt..,1:0b.,..in

b.ilkcr h diente1e1:0 d...e'SiY tleir tlod cp,ons. Fh°'° t,.. SA. t«Ae\m~s

Me<illh c.re resruroe:s nirn~n aai1iail sllS~n.bilityissi.,e or iSl.nd li'-'nt Fh:11:0bySA. M;Ae,µ,lds

RISING TIDE

I

college oh rtsand sciences

I

16

Invasion of an Aggressive Crab A.RKJJ_S£BE.DE.RLCl:l ,2l:I .Da,2.RD£ E_S_S_Q.R, DEeARIME.til..OF..MARLliE_S_CJ_EH_C_ES.__ _ _ _ _ _ _..

lhe 9Jl'(pEm Gl'Wl O'.b,Co atxcs t1108)0S,is one otf'lernost si.,o:es:s1U irNaSi...e spedes imt1d1Mde. se.er<ii sUies at lhe UN EMaine Sden::e <enw in.eSigate tie E!()jogyard pt"¥idogy Off'lis a.ib 101Jrderstnl its irNaSi...enes:s in h c:mtextotglobal diimte cm•

How do ~u get rid of an aggressive and destructive

h}'brid crabs from NCM> Scotia seem 1o be slowly

invasive marine crab? First, ~u need to understand the biologyof that inva::ler. This is exactlywhat Markus Frederich, Ph.D., professor of marine sc ences,and his team of graduate and undergra::I uate researchers

invading Maine waters. Frederich and his team are working on investigatingwhatdama~ th is new invasion will cause.

aim to do.

Frederich and his team are investigating the Euro~n

green crab, Corcinus moenos, including how the g:JneU:allydifferent p:,pulatbns in Maine, Nova Scotia, New1bundland and Iceland vary in aggressWeness, tehavior and stress toerance. By pla: ingc rabs from different p:,pulations into an artiflc ial eelgrass ted and mon itoringthe resultingdestructbn, by running the crabs on a treadmill,and byexposingthe crabs to changingtemP3ratures and salinities and assessing resulting protein and gene expression, a detailed understandingof the intricated ifferences between the p:,pulatbns sbwlyemerges.

Initial data show the crabs from Maine as the more

docie p:,pulation, while the crabs from Newfoundland are more aggressive. While Maine and Newfoundland crabs are ~reU:allydistirct p:,pulations, thecrabsfrom Nova Scotia are a h}Orid between toth and are so aggressive that theyeven jumpout of the water to attack. To ma~ matters worse, the veryaggressWe

171 collegeofartsandsciences I RISINGTIOE

.orober Jerkins (Miline Sdences, '19)sN'Ches fer irNa.<i...e spedes at tieooast ot Eiiddmn:I Pool.

Fh:11:0 byJesSica 9'1.!nper

ESTABLISHING A NEW INVASIVE SPECIES MONITORING SITE AS PART OFT HE MIMIC NETWORK Removingan established invasive sP3cies from an ecosystem is nearlyimp:,ssible. Therefore,several programs and precesses were established to track and monitor invasive sP3cies, to either remove the very first invaders or to understand the dynamts of

Frede rt h's team will continue to monitorthis MIMIC site monthly for the next few ~ears to evaluate trends in the abundance of present inva:lers and to identify potential new invalers.AII data will be included in the MIMIC database and will help in the ongoingeffortto manage and monitor invasive s~cies in New England. a

the respective invasions.

In New England the Marine Invasive Monitoringand Information Collaborative (MIMIC) monitors more than ti) sentinel sites on a monthlybasis 1br a sP3ciflc set of 16 invasive sP3cies. Frederich and his team of undergr.d uate and gral uate students established a new MIMIC moni1oringsite at the coast of Biddeford Pool and assessed itfor invasive sP3ciesfrom May X:.16 to Septemter X:.16. Eight invasWesP3ces were found: Botr-,loides violoceus. Botr-,lus schlosseri, Corcinus moenos. O:x:Uun frogile. Dkie.rmumvexillum, l-emi$"opsus sMguineus. Membrc::nip,ro sp.. and Ostreo edl.Jis. The abundance ofthese sP3cies varied throughout the summer, with seasonal trends for some spec es but not forothers. So far, no new, presentlyu nknown invasive s~cies was detected in the new MIMIC site.

L.IJtlfl Dllffn (~ine Sderoe:s ;17)1Jsesa 3D<ligiiizEr to o:rnpn lhe

roorpl'ology otgreen a a t'crn loel.n:I,<.nada .nd ~ne.

Maine Sderoe:s Protessor ~lo.IS F'h?deridl, Ph.D. ,.nd tis ~dents perlct'rn a roonlh1ysU'...ey tlr irNaSi...e spedes asp.not tie Maine lrNaSi...e Mmi~ng & htcrlmlion COll<ibcrall...e. Fh:11:0 ~ JesSica sunper

RISING TIDE

I college oh rtsand sciences I 18

UNE's First Artist-In-Residence Moves Students Forward JE_SSEMJ.L.L.E.R,M ..EA. ,.ILLSLII N__G_A_S_SJ.SlAlil L.EClU.RE."-- - - - - - - - - - - - - - - - - - - - -

"Everythingthat I do is an expbratbn of movement,"

exclaimed Kim Bernard, M.FA., UN E's first artist-inresclence, leaping from her chair te1brea classroom of smiling, wee-eyed students. Bernard~ work, much Ii~ the artist herself- kinetic, interactive and communityfccused - is often situated at the intersection of art and science.

Growing up, Bernard alwa}IS knew she wanted tote an artistbut ha:I no idea how imp:,rtantsciencewoutl be 1o her work. As Bernard explained, 'With each and every kinetic sculpture I create, I learned more a tout Newton's laws, me: hanics, resonance, harmonC oscillation, wave interference - the list goes on. Ha:!

I only known in high school what I'd become most curious a tout later, I might have paid more attention in science class."

As U NE's artist-in-residence, Bernard is charged with developingscience-inspired works of art and assistingfclcultyand students. Visiting Assistant Lecturer in English Jesse Miller invited Bernard into his classroom to speak with students in his An lntro::luction to the Humanities class. Duringan intimate seminar, Bernard descrited how the immobilityof several family memters - inc ludingthe paralysis of herfather- significantlyaltered her life.

From those difficult exP3riences, however, Bernard has found inspiration, transformingthem into art.

Lauren Gerhard (Education, '20)observes, "Taking the sympathy and pain she felt 1br her lo,ed ones, Bernard weaved her IOl!e ofart1ogetherwith physics, engineering, the studyof sound wa-,es and science to buitl her sculptures. The ways he fusesartand science to~thertoc reate such stunningyetsimplistic pie:es is trulyamazing."

Bernard's post on campus signals the vital imp:,rtance that toth science and art ha-,e in shapingthe lives of students at UN E. At the completion of her residency, Bernard will create one newworkofart, which will tecome part of UNE's P3rmanent collection.

To see of more of Bernard's artwork, visit w-vw.kimternard.com a

UNE's 1irst.r'1ist-in-reSidence ,l<irn 9Em.td,',tsitsv,UhJesse Miller's AA 1n1rod1ÂŁion 1:0 h 1-tirn.niies dass in f'let<111 Of 2016.

19 I collegeofartsandsciences I RISINGTIOE

STAY ON

TOP OFUNE NEWS From Maine to Morocco

at www.une.edu/news and follow UNE on

000(11)(1

.

~ RISINCTIOE

I

20

I

I

Interview with Alex Campbell: UNE's Only Philosophy Major DAVID LIVINGSTONE SMITH, PH.D., PROFESSOR, DEPARTMENT OF HISTORY AND PH I LOSOPHY Aleo< Campbell graduated in 2014:theoneand only philosophy major in the historyofthe Universityof New England. I caught up with him at Indiana University, Bloomington, wtere he is doing graduate study,and asked him

Camptell is now immersed in graduate study in the history and philosophyof science and isenjoying his exP3rience in Bloomington.

His main a:a::lemic interests are in bicethics, the philosophyofmedi: ine and the phibsophy of biology. I asked him a tout his future plans, and he eo<plained that he is looking forward to combining his philosophical and scientific interests. "I plan to attend medical school," he said. "I want tocombine philosophyand medicine to a::lvance the role of bicethics in Amertan hospitals.''

a learner-centric educational model.

Studentsofthe millennial and p:ist-millennial generation, raised on mobile devtes, digital games, texting,scc ial media and connectivity an'YWhere, are not novtes in usingd igital courseware fortheir success. Health professionsstudents at UNE are required to ta~ a two-semester anatomy and physiology course (A&P), which immerses them in an engaging learner-centric environment created with avarietyofdigital courseware.

These tools offer multiple remediation p:,ints toensure studentsuccess.

some questions atout his academic trajectory.

In particular, UN E's Bia: kboard learning 'When I firstcame to UNE, it was because of my interest in physical cceanographyand environmental science," Cam ptell said, "But

managements'YStem, coupled with the textbook publisher's SmartBookAdaptwe Learning platform, creates au nique in-class/ out~f-class digital learningsp:ace. Thisallows each ind Widual to progress at his or her own

during myfl rstsemester, I hapP3ned to pick two philosophycou rses with Dr. Smith to meet some of my core requirements and was soon enthraled."

He went on to tell me that he discovered that philosophydissects how people think a tout the relations between concepts in W'ilfS that he hadnt eo<perienced in any other field of study. "After I found this passion," he sat!, "I knew that I wanted to major in philosophy.

UN Edoesnt offer a phibsophy major, so I created myown P3rsonal major."

Next, I asked Campbell what he thinks the studyof phi bsophy has to offer to students at UN E. He was adamant atout the importance of phi la;ophyfor anyfie Id ofsbJdy. "Philosophy helps ~u to discover conrections tetween the disciplines," he remar~d. "In myexP3rence,

a lot of science majors thinkthat philosophy isn't relevanttotheir interests. That's just

not true! Philosophy is rigorous and

transformative. It tea: hes ~u how tothink clearly and precisely,and it greatlydeeP3ns your understandingof science." After a moment's thought, he added, "Maybe most importantly,stud}'ing philosophy helps you learn how to earn.''

211 coHegeofartsandsciences I RISINGTIOE

sP3ed th rough the course materials, which are tagged with Bloom's taxonomy levels.

Students can engage in remediatbn until they .oJe.c<.rrpbell, B.A '14(Ftiloscpl\,)

haveachieved theirdesired level of success.

The analytics from the adaptive learningtool help the instructortaibr in~lass tea:h ingand discussions to meet areas of student need.

The Digital Promise: Reshaping Teaching and Learning via Student Engagement to Improve Success and Retention KAUSHIK O<ASH) DU TIA M.S.,ASSOCIATE LECTURER OF ANATOMY ANDPHYSIOLOGY, DEPARTMENT OF BIOLOGY. In the A&P lal:oratory, students use a digltal Several advanced tech nologes have c han~d the landscaP3 of tea: hingand learning in higher education byofferingdigltal tools and resources to educators and learners. Many lowcost,lnocost solutions offer incremental change and a::lded value to the intrinsic quality of undergraduate 1ea:hingand helptodevebp

ca::laver program with la}eringtech nology to explore the anatomyofdeep structures.

They also use adigitaldataacquisitbn system, delivered via a cloud server, to engage in hands-on physiological exP3riments. Last but not least,a digitalsocial media platform fosters a sense of com mu nityamong earners where

students can engage in high-level ~er»~er intel'3:tions. Collectively, these technological implementations have incrementally improved studentsuccess and retention in A&P over the years.

• %0f~denl:Sachie-.t"' ¢ ~ • %0f~dentsachie-.t"' ~~

su rroundingth is Saco Bay island. The research vessel will carry upto 24 UNE

Afterstud~ng medical biology as an

students, fucultyand staffat a time.

UN E's master's program in biological sciences

Add ltbnally, Girard g,,,e UNE a 350 Marlin FM that will transport students, r.,cultyand staff offshore to conduct field science.

Christened "SharkologY,"the vessel is 35 feet longwith twin 2005Yamaha 3:10-horsepow-

23

er outtoard engines and can carry upto

15

eight U NE students, fucultyand staff.Adding these two boats to the U NE fl,etopens

•

o .__ _ _ _ _ _ _ _ _ _ __

undergraduateat UNE, Follansbee enrolled in and researched the mechanisms of pain using

the fruitflysystem in Geoffrey Ganter's lab.

The project, which was supported by the Center for Excellence in the Neurosc enc es

and its NIH Center of Biomedical Research Excellence grant,allowed Follanstee to identifyseveral ~nes required for injuryinduced pain sensitization.

exc itingnew p:,ssibilities for teachingand

These ~nes, the subjects ofa first-author

student research.

manuscriptcurrently in review, may represent

tar~ts for novel drugs fort he treatment of chronic pain. Follanstee presented his results 1terdsins1'.dents1.1X1eSs.n:I retenlicn h A&P:green indcates a deaeasi"' peroen~ Of ron-q.i<llif\i"' sil.dents ovu-lime ~dents rn1.1St adli~ a grade ot ~ 73peroent 1:0 progress in tlEir P'CW.rn).b11..e indcates tie iraeaSing peroen~OfA~~tsovu-lime.

atthe Genetics SocetyofAmerica's DrosoJ:ilila Research Conference in San Diego, California,

and at the Maine chapterofthe Society<or Neuroscence in Orono, Maine. In additbn, he hel~d Ganter prepare an application to the National Institutes of Health's Academic Research En hancementAward program. The

UNE Marine Science Center Acquires Two New Research Vessels

applCation was successful,and the three-~ear (F'h:rn left 1:0 tighO Micha,j Gr.rd,J.rnes SUikowstd. Fh D., Ed Elil*y. Ph.D.,At1hU' Gr.rd, Adjie <o.,iac, M.BA., .n:l lirn Alien1i, B.S. .enb.rk l,pcn f'le maiden Of S,o ,lob&(not picved r.ll~Ono,Ph.D., v.h:lwas <11soonbo.t'd)

..o-..

UN E marine programs are now moving

offshore. The recent gift of Ram Island from Arthur P. Girard allows forteachingcou rses in marine sciences, environmental sciences/ studies or biology on UN E's own island, just one and a half miles from campus. After acquiringthe island, UNE commissioned the construction ofa 31-footalum in um

He continued tosaY, '1"his environment

Maine Alumnus Continues Science Career in California

and research methodology,and it instilled in me the confidence to give presentatbns, which has teen essential to my risingcareer."

Ganter ho~s that many more students with talent, curiosityand determination Ii~

While he grew upcanoeingthe Kendus~ag

Follansbee's will ta~advanta~of transformative research e0<perences with UN E's r.,culty.

Stream in Maine, theseda}IS Taybr Follanstee,

B.S. '13, M .S. '15 can occasionally be found hikingin the mountainsof California. But most

Landing Craft. In addition totransp:,rting

days, Follansbee is workingon his Ph.D. in his lalx:ratoryat the Universityof Calirornia, Davis,

vessel will allowstudents toconduct basic

studying the sensation of itch with professor

oceanographic and marine biologCal field

Earl Carstens.

science on the way to and in the waters

allowed me to learn a tout rigorous sc ence

GEOFFREYK. GANTER, PH.D., PROFESSOR, DEPARTMENT OF BIOLOGY

Student-Centered Research Capable students, facu ltyand staff to Ram Island, the

Follansbee recentlycredited UN Eprofessors forcreatingwhat he called "an environment of approa:hability,centered on trainingstudents."

ADDIE COYAC, M.B.A.,ASSISTANT DIRECTOR, MARINE SCIENCE CENTER MARKUS FREDERICH,PH.0., PROFESSOR, DEPARTMENT OF MARINE SCIENCES

$443,4~ grant now supports Ganter and his group's continuing research on pain.

~er F'Oll.n~ee. B.S. '13. MS. '15hib:srnrunt.ains in'itlsemaie.

RISIHCTIOE I COll~Ofartsandscieoces I 22

I• •

lf fI} •.

····-4/NE HEALTnf.JUI,,_ -

t1mfs

,•,w·P(.1-tnh, ,,/TfllllV""' :rv1 ld11•

v

I

I

WAD EM- UNE. tie UNE Addeicn ~idne <11.b ,JOSEPh WOIOerg .~lll'Ct p-otessor in tie Pl'¥id.n AssiSWltprogr.rn .nd C.r1a J:ltnscn ,ox,n:lna\17 ot <runseiingser.;oes at UN E,pose v,Uh tie £./¢ala ~line Assis\l:d G'Olllh .nd Leatnng Assoda,on) 11~IY4's .nd iheir hcnes.

In October 2015, the World Associatbn for Disaster and Emergency Medicine (WADEM)extended an invitation to the UN E College of Osteopathic Medicine (COM), asking Its students to form what would be the flrststudentclub tote partofthis international organization, as a pilot, te1bre they consider enlisting students from other med Cal and health-science schoo~. WADEM links the militaryworld with the civilian world, and the potential for improving global emergency health care is greater than it would te with the two worlds functioning indeP3ndently.

WAD EM wants to involve anded ucate future health care professionals from around the world in its ongoing efforts to improve preparation and intervention in disaster and emergency medicine.

Guided by COL William Bograkos, MA., 0.0. '85, president 1brthe American Osteopathic Academy of Addiction Medicine QIOAAM) and advisor for the Association of MilitaryOsteopathic Physiciansand Sur~ons (AM OPS); Victoria S. Thieme, D.O. '93, advisor for the Addiction Med Cine Club; and Jennifer Gunderman, M.P.H.,assistant lecturer in the School of Com munityand Population Health, WAD EM UNE endeauors to mentor future health care leaders in thed isc ipline ofd isaster med Cine.

25 I collegeofosteopathic me:licine I RISING TIDE

Communication, collaboration and cooP3ration are the skills thatdefl ne ah igh-functioningteam and are absolutelycritical to disaster resp:,nders. As such, students in the WADEM-UNE clubseekto immerse themselves in new situations totesttheir abilites and encounter new opp:,rtunities for growth.

As UN Efunctions from two primarycampuses, the students are earningto bridge the ~ographical barriers while plan ningand workingtogetherto develop presentations,outrea:h and other learning a:tWities in the discipline of disaster management.

Compassion allows wisdom to grow within each of us if we are supported and encouraged to peoceive our similarities and our differences as human beings- Staceylhieme One such activity is leadershipand team buitl ing through Equine Assisted Therapy. After ad isaster, victims may need a wide ran~ of services and assistance,and disaster resp:,nders are sP3cially

trained and equipped 1o help. But the resp:,nse team~

that need mcdifying. This event inclu::led representation

theory and skills need 1o be developed in a safe environment - one that offers the opp:,rtunityfor discussion and refection, in order 1brthe students to fully understand the role theyplayon the disaster-

from the Colegeof Osteopathic Medi: ine and the COiiege of Pharma:y, from faculty in the Physician Assistant Program,and staff from the UN EPortland

resp:,nse team. Workingwith the equine therapy

mind-blowingand heart-o~ning,''sacl participant Garia Johnson.

staff at River Wind Farms allowed the WAD EM-UN E club (and also the Add i:tion Medicine Club)1osurpass their comfort levels, learn new skills and continue developing patientcompassion.

"Compassion allows wisdom to grcm within each of us if we are supp:,rted and encouraged to P3rceive our similarites and ourd ifferences as human teings,'' eo<plained StaceyThieme,D.O. Equine-assisted learning has grown in p:,pularity over the last few years as health care providers recognize the lim itationsof purely pharmaceutical

interventions. As WADEM-U NE is a meldingof the civilian and militarycommun ities, this four-hour

event was the fl rsteftbrtto reach outtothe greater UN Ecom munitytoteach and earn leadership and team-buildingskills. Horses were the patients. The

Counseling Servtes. '1"he ex~rience was

So, whoshou Id join WAD EM-UN E? Students with an interest in public health, global health and emergency medicine are the obvious participants. However, you should also join ifyou are interested in learningstrategy and o~rations as a team mem terwhile carrying out a health care intervention. WA DEM seeks both civilian and militarystudents. Our goal is to faster eadershipand team-buildingskills whileaccumulating knowledge around disaster preparedness and intervention. Otherareas of conversatbn with in this group include: What is a disaster?Who is affected by a disaster? Whats~cial p:,pulations need a plan in pla:e in case of a disaster?Whatare the differences tetween the intervention needed in an underserved p:,pulation versus a well-resourced p:,pulation duringa disaster?

patients were rather large and stubborn and enj~d

eatinghayand pla}'ingwlth ea: h other. The equine therapists chal i, n~ the srude nts 1D see hcnv the equine

Since everytx:dyin the health care field feels resp:,nsible in the aftermath of ad isaster, why not

tehavior was similar to that of a patient with Ty~ 2

join WAD EM-UN Eand learn 1o be a participantand

diabetes who does not want 1o attend 1o behauiors

an a:tive partofasolutbn! •

Joseph wcuberg, ~llrct p-o*s:scr in f'le Ft'¥id.n AsSiswit p-ograrn•.nd <.rla Jdlnsm ,ox,n:li~r Of UN£'s oo.,nseiingser..,;ces, ta~ great tisks 1:0 c.re fer lheir ~ent,dem:1nwaling coH<iboralion .n:I oonrni1rtienl

hn<obett~OM,"19).n:I LitbyManeo~OM, '19)hadtol1Se lheir assets .n:I omtk as a tN"l'l to ~gate tieheaiti c.re sys tel"!\

R1S1HCTIOE I collegeofosteopathic me:licine I 26

In May of 20151 recei\!ed the firstof what turned out

to be manyoutbreakalert notices describingcases of fever in Brazil associated with Zika virus. I raised my e~brows, mildlyinterested,and then scrolled on to

the next notice. I had heard of Zika in passing, but I cou kl n't ha\!e told }OU much about it other than that it was a disease no one thought of as a crisis. As 1br the cases teingrep:,rted in Brazil? I shrug~d them off too.

It is notsp:ctacularlyunusualtosee diseases leap from one part of the world to another in the age of air travel.

I had flippantly dee ided that these cases of fe\!e r and rash, none ofwh th were fatal or complicated in any Wa'f, were not remotely interesting. I was wrong.

surprised to receive an invitation to the Zika Global Health Sym p:,sium held in May of 2016,just u ndera }Oarto1he dayofthe first cases being reported in Bra2il.

Two things became very clear to me up:,n myarrival: 1) most others in the room weresimilartysurprised to have teen invited (as it turns out, there were almost noZikavirusexperts walking the planet prbr to 2015); and 2) ea:h invitee had a separate and transferrable skill that could be appled toZika research. There was one scientist who designed va:cines, twowhostudied the way that the immune system initially intera:ts with similar viruses,one who designed latoratorytests

These cases would lea:I to the alarmingclin ical discoverythat infection with Zika during pregnancy could lead to severe neurological defects in

newborns and a higher rate of stillbirth, a looming health infrastructure challenge as these profoundly disabled infants grow intochildren ,a swift and impressive mobilization of the scientific community toe reate p:isitive outcomes for those at risk,and for me,an u nexP3cted new line of research.

Firstthingsflrst: I am not a virobgist. I studyemerging diseases and the Wa'f infectious agents evolve, but I prefer ba:teria. Occasionally, I have been asked to measure the e\lOlutionaryp:atterns ofother pathogens (parasitic worms in particular), but I had never felt p:arU:ularlyintrigued byviruses. I was, therefore,quite

27

I

collegeofosteopathic me:licine

I RISING TIDE

~gtm M~. Fh D. ,desaibes tie p-ooe:ss Of ed1ing .n:I e...ai~nggE'tt seq.imngdata 1.1Sed in tie ÂĽtins t-ologyot Zika sil.d\l

to detect infectious a~nts, another who studied neurological pathology in infants during pregnancy, a few whostudied intera:tions tetween viruses and mosquitoes, and manyothers.

The reason for my invitation tecame cear immediately; it was tecause no one knew much of anythingabout how Zikaevolves and changes. We as a sc entiflc and medtalcommunity need tangibe outcomes to provide 1othe pu bli:, and, in order1oachieve that, we had best understand the fac1ors pressing on Zika that caused ittog:Jfroma relativelytenignvirustoone

These findings have great potential 1o inform the way we design laboratory tests and vaccines tecause it is far easier to hit a st:abletar~t than a moving one.

Further, our study found that some of the evot.led changes seemed 1o vary the function of the Zika~ proteins in meaningful Wa'fS. Most notably, we 1bund that a small chan~ that all ofthe Western Hemisphere isolates had in the envelo~ protein made them able to interact with neu rans, p:,tentiallyexplainingwhy we are suddenlyseeing impa:ts on the brain. We published this studyin September, just four months after the symp:isium.

that targeted the brains of fetuses.

My lab began 1ostudytheevolution ofZika virus by looking at its ~netics. We took the compete genomes of 33 different isolates, aligned them to find the differences, and then explored the bbbgical impactof those differences. Toensure that we were not biasingtheoutcome of our study, we were carefu I 1ochooseZi~ isolates fromalloverthe workl (11 from Africa, eight from Southeast Asia, 14 from South Amer ta or the Caribbean),over the course ofdecades (194 7-January 2016)and from a variety of sources (human plasma, infected wildlife, mosquito p:ols and p:ist-mortem isolates from bst pregnancies). When we bo~dateach Zi~geneand i,er1brmed ourevolutbnary analysis, it was very clear that the virus preferred to ~epsometraitsveryst:able and yet was at its biological test when others c han~d extensively.

It was ju stover ayearagothatZika infection was first lin ~d 1o the severe birth detect mi: rocephaly. Since that time, researchers from all over the world have coo~rated and shared their findings in Wa'fS that are almost unprecedented. Why? We need tangible,solid tools to apply to this crisis. Perhaps it is tecause of Zika's impacton the most vulnerable among us, but this disease has created a ferventdemand for rapid outtomes ct sbJd ies that is rarely seen. On be halfofthe UNE College of Osteopathic Medicine, I am pleased to have provided some context to choose Zikavirus targets and am similarly pleased to have provided continuing medical education trainingon Zika for COM alumni in October. The end goal for all of us is p:,sitive clinical outcomes for patients, and, on toth research and physt ian-training levels, COM has taken action

toward creatingp:isitive outcomes for Zika patients. â&#x20AC;˘

R1S1HCTIOE I collegeofosteopathic me:licine I 28

Among Middle-Aged and Older Persons" at UCLA Medical Center, California (UCLA Mentor: Ali son Moore, M .D.). The project led to a peer-reviewed publication.

Gioia Guerrieri, D.O., a 2008 graduate of the University of New England College of Osteopathic Medicine (COM), has worked diligently since her acceptance at the college in 2004 to advance knowledge and practice through research.

Upon Guerrieri's acceptance into the college, she jumpstarted her research career by applying for and receiving her first COM Dean's Research Fellowship, titled,"UNECOM First Year Medical Students Perceptions of Older Adults: Pre and Post Curriculum Measures:' She was awarded this fellowship even before her medical school classes started. As Guerrieri's research mentor from her arrival at COM to now, asherpeermentor, Marilyn R Gugliucci, Ph.D., professor and director of Geriatrics Education and Research, has witnessed firsthand Guerrieri's tenacity in advancing her career development and job transitions through research.

Thefoundation of Guer~e~¡s career continued to build as she progressed through medical school.

In the spring of her first year, Guerrieri was awarded the highly-competitive American Federation for Aging Research (AFAR) Medical Student Training in Aging Research (MSTAR) Fellowship, She researchedthe "I mp act of At-Risk Ori nking on the Development of Disability

29 I collegeofosteopathic me:licine I RISING TIDE

Guerrieri then presented the results of the AFAR M STAR research at the Northeast Osteopathic Medicine Education Network (NEOM EN) and was awarded first place for Student Original Research. She also presented this research at the American Geriatrics Society (AGS) 2006 Annual Scientific Meeting and was awarded theAGS President'sAward for Student Original Research. These honors were quite e>(traordinaryto attain as a second-year medical student and spoke to Guerrieri's talents as a researcher.

During the summer before herthird year of medical school, Guerrieri became the second COM student in ten years to attain the highlycompetitive Betty Ford Center Summer Institute for Medi cal Students (SI MS) Fellowship, which enabled her to work with patients and their families at the Betty Ford Center. Guerrieri expressed early on in medical student training her desire to pursue psychiatry as a specialty.

She was al so one of twenty medical students nationallyto be awarded the Boston University Medical School and American Geriatrics Society's Geriatrics Summer Institute Award.

Guerrieri's student leadership e>(tended beyond her roleswithin the Ame~can Ge~atrics Society/ UNE COM Student Chapter(co-president) and the UNE New England Research Club (co-president).

She was elected by her medical student peers as chair of the the American Geriatrics Society National Student Health Professionals Special Interest Group. Despite the AG S's strong allopathicfocus and leadership, Guer~e~ worked with medical students across the country to organize symposia sponsored by the AGS student organization at the annual meeting.

Through her clerkships, she continued to apply herself to research aswell as leadership, attaining a COM Dean's Research Fellowship during her fourth year.Her project, titled ''Timing and Referral Patterns of Hospitalized Patients on Medical Floors to Psychiatric ConsultationLiaison Services;' contributed to Guerrieri being awarded the Madeleine McCormick Osteopathic Education Scholarship, She was one of 20 medical students and residents selected to participate in leadership training forwomen in medicine and mentorship, She also authored a Medi cal Student Beginner Guide to Research, which she dedicated to UNE's COM students.

At graduation, Guerrieri matched at the Mayo Clinic, Minnesota, psychiatry residency program and continued her passion for healthy aging and clinical research by working with neuropsychiatrists on geriatrics depression, becoming the chair of the department's resident Neuropsychiatry Case Conference and becoming an Internal Review Board (I RB) member. At the Mayo Clinic, she received an academic appointment and was awarded the Resident Psychiatric Research Grant (an American Psychiatry Institute/Janssen Scholarship for"S-HTILPR Polymorphisms as Predictors of Response to SSRI and SN RI Treatment among Depressed Persons Aged 50 and Older·,. In addition, she received the Mayo Clinic Department of Psychiatry honors for"outstanding team member" and "significant contributor to geriatric psychiatry" in 2010.

In2011, Guerrieri was one of two residents in the nation to be accepted as afourth-year psychiatry resident to the National Institute of Mental Health (NI MH) Division of Intramural Research Program. During her fouryears of clinical research experience with Peter Schmidt, M.D., section chief of Behavioral Endocrinology, she became an associate investigator on several protocols in reproductive endocrine-related

M<lil\fl R. 04l1JOO, Fh D. ,has been GoiaO..erri(Si's reseadl meMOr shoe2003. 041~o:1 is tie dire;tt otOEriWk:S Edi.alien .nd Re:sN'th v,Uhin h

UN£ C.-.tsicn otGErialrlc ~ddne.

mood disorders, focusing herwork on the hypothalamic-pituitary-adrenal axis in premature and norm ally timed menopause, premenstrual dysphoric disorder and postpartum depression.

She has published in /Vlenopa use, JAMA, Neuropsycho/ogia andArchives of Women's Mento I Hea Ith. She al so started her private medical practice (Well-Minded) during that ti me, which is an outpatient practice focused on healthy aging, women's behavioral health and osteopathic principles.

Since 2015, Guerrie~ has served as a regulatory medical officer forthe Food and Drug Admi nistration (FDA), while continuing her professional development at the NIM Hand maintaining her private practice. Currently, she is revising the Medical Student Beginner Guide to Research by adding the pearls she gleaned as a resident "research-track" and clinical research fell ow.

Pub Iication is planned for 2017.

Guerrieri's awards, fellowships and publications attest to her multiple strengths: intelligence, training, passion and ability to work com passionately with people of all ages.Guerrieri is recognized for her numerous servicesto the UNE College of Osteopathic Medicine and its students.

She is a wonderful ambassadorfor research training of osteopathic medical students. • R1S1HCTIOE I collegeofosteopathic me:licine I 30

about the changing ado I escent brain. When the child i syoung, parents make decisions forthe child. As the child grows and the brain grows, the chi Id needsto be all owed to make some choices alone. Hopefully, you've learned how to make good choices by the timeyou are a young adult.

This takes practice and lots of communication."

But as we all know, not everyone has an opportunity to develop these skills equally well.

Thieme's goal was to really rei nforcethe fan that the decisions people make have real, tangible consequences. Students needed to examine their own behaviors and aaively, consciously change some of them.

Victoria Stacey Thieme, D.O., di rector of Community Medicine in the College of Osteopathic Medicine, has been encouraging the students of St. John's Cat hoIic School to cultivate a deeper appreciation for science and its application to their I ives. Forthe past four years, Thieme has been visiting her daughter's class and giving presentations on science topics.

A background in addiction medicine and health education made Thieme an e:,ccellent liaison for these activities. Thi syear, when a teacher sent out a letter to parents regardi ngthe changing bodies and brains of the students, Thieme knew she needed total k about the adolescent brain on her next visit to the school.

As Thieme explained, "When the sixth-grade teacher sent an educational arti de to parents describing the struggles of the parent-child relationship astheyoung brain and body matures, it made sense to make this year's presentation

31 I collegeofosteopathic me:licine I RISING TIDE

I want to be a doctor when I grow up, so this was a great learning experience. Getting to use a scalpel was especially cool.

I hope you can do more fun stuff with us next year!

- Clare.St. John's5thgradestudent To get students examini ngtheir own behaviors, Thieme began with an aaivity that refreshed them on the parts of the brain and the functions of the varying brain areas. From there, they moved on to communication - namely, how the different areas of the brain talk to each other (vi a electricity). The pre-frontal cortex wasthe leader, the midbrain wasthe emotional center, and the hind-brain served as the survival area. The students needed toforcethe pre-frontal cortex to Ii sten and understand the needs of the other two areas, without surrendering control. When the emotional and survival areas makethe ded sions, they are not as well thought-out and can have long-term negative consequences. The pre-frontal cortex is the "voice of reason" and needsto be taught how to lead, especially during times of stress.

If I can touch one young person's life in such a way that they say 'no' to drugs, say 'yes' to health, 'yes' to compassion, and learn to cope and deal with life's stressors, then I will be grateful for this time with these students.

- Victoria Stacey Thieme Armed with sheep brains and dissection kits donated by the UNE Center for Excellence in the Neurosdences K-12 Outreach Program, Thieme created several other activities forthe students.

Thieme utilized the sheep brains to explore brain anatomy- such as identifying brain regions and functions- and used bike helmets mapped with the cortex regions of the brain to explore how easily the brain can be damaged. The students al so created atim eli ne to evaluate different changes in the body, mind and mobility overtime, from infants to ado I escents.

These students will be some of our future community leaders; therefore, we must prepare them and arm them with knowledge and mentorship.

- Victoria Stacey Thieme The results of these vi sits seem to be overwhelmingly positive. Clare, a fifth grader from St.Joh n's, thanked Thieme with a note that read, "Thank you so much forteaching us about the brain. Di ssecti ngthe brain was really fun and interesting. The brain helmet was really funny and the Kit-Kat was delicious. I want to be a doctor when I grow up, so this was agreat learning experience. Getting to use a scalpel

Ci<ily O'l.rbmne<11.1 .n:I <I.re MacDoMd elÂŤl'lini"' abrain .nd o:nSidEring tow tleirs mght be sin'il.r.

was especially cool. I hope you can do more fun stuff with us next year!"

Thieme's teaching goal i sto inspire future passionate scientists, osteopathic physicians and amazingly awesome members of society.

"If I can touch one young person's life in such a way that they say'no' to drugs, say'yes'to health, 'yes' to compassion, and I earn to cope and deal with life's stressors, then I wil I be grateful for this time with these students;¡ she reflected. "These students will be some of our future community I eaders; therefore, we must preparethem and arm them with knowledge and mentorship."

Thieme is grateful to UNE for providing opportunities and sup po rt for herto pursue ongoing educational outreach in the local community. â&#x20AC;˘

R1S1HCTIOE I collegeofosteopathic me:licine I 32

---~.

A COMPARISON Of SEROTONIN, MEDIAL PRE-FRONTAi. CORT A ~ t . D.C. 80.ut. P I Ocpl ~1°'9Y. z

1""9C lolw Ch.ldr(ll·s

e. AND NOREPINEPHRINE IN THE feMAi.E AOOI.ESCENT RATS

Gotlu' 1 -,D..1 Molder'' ,dddiwd ME. 0400, Sc.kooa, los,on.MA Olll6

. ------~ - :j::·.:~ -.--_-:-----~--:;.-;

-----:: :;5-::

There is a btthatgces into an education .A goo::I education must include notonlyclassroom learning but also experiences outside the classroom. Students come to UNE for toth the classroom learningand for the uncommonly broad rang:J of opp:,rtunitiestowork with fa:u ltyin their research labs. An a:lvantag'J of doing undergraduate research at UN Eis that, unli~ large research un Wersities, UN Edces not have many graduatestud,ntsard p:,s~doctx:ralfelbws. Therefore, undergraduate students have much larger roles in the lab,often conductingtheir own projects and gaining authorshipon publications. And as fa:ulty, we teneflt from the hard work and enthusiasm of the students. I ha11e benefited from tv.ofantastic groups of students helping me with myresearch: the medical students from the Colege of Osteopathic Medicine (COM) and the undergraduate studentsfrom the Colle~ of Arts and Sciences (CAS).

The Federal Work Study program has been ah u~ benefit to my students and 1o the research. Th is program has albwed students 1o be paid tor their v.ork in the labwhiletheyare getting research exP3rience. CAS has attra:ted students whoa re interested in doingtheir undergraduate program at au niversitywith gra::I uate health sc ence programs.

Since the undergraduate students know that having research on theirapplications to advanced degree programs helps them gain admissbn tottose programs, they are motivated to join the research labs. Soon, however, they learn that the research, it:se If, is e:xc iti ng and imp:,rtant. Some become involved to the p:,intof teinggWen their own ~oject:s, leadingto presentations

at natbnal meetings and, finally, publication in p:errevewed j:,urnals. Regardlessof hcnvfar they~ in their projects, they always have a sense of accomplishment.

The COM students have so much 1odo in their two short ~ars here on campus, I am constanttyamazed bytheirability1oget research done too.

These COM research fellows have included Tammy Hay, 0.0. '90; Linda Stambaugh, 0.0. '91; Fran kPar~r.

0.0. '92; Kath een (Leahw COrreia, 0.0. '92; Robert Moore, 0.0. '93; Sherry Stadig, 0.0. '98; Gudbjorn (Karlsson)Asm undsson, 0.0. '99; Heidi Wennemer, 0.0. '00; Janice Grivetti, 0.0. '08; Jacqueline Ciancosi, 0.0. '11; Ethan Beaudette, 0.0. '14; Nicholas Church, 0.0. '15; Sandi Chen (COM, '18); Tim Newell (COM, '18); and Shiva Kolangara (COM, '18).

33 I collegeofosteopathic me:licine I RISING TIDE

The CAS students have included John Pare, B.S. '88 (Life Sciences), D.O. '92; Allison Gully, B.S. '93 (Life Sciences); Kristy Ch bda, B.S. (Marine Bblogy); Greg Cadman (COntinuing Educatbn); Barbra Whitten '93 (COntinu ing Education); Tracy Sklutas, B.S. '91 (Marine Biology); Sal Abbruzzese, B.S. '95 (Life Sciences), D.O. '99; Sherri Field, B.S. '94 (Life Sc ences), D.O. '98; Nancy Theriault, B.S. '96 (Medical Biology); Donna Laverrere (Occupational Theraiaj; N i:holas Clay1on, B.S. (Med i:al Biology); Mark Graves, B.S. (Medical Biology), Ph.D.; Eric Housner; Sarah Sine lair, B.S. '97 (Life Sc ences), D.O. 03; Heather Mastalong, B.S. (Life Sc ences), D.O. '00; Valerie Trumble, B.S. '96 (Life Sciences), D.O. 00; Charles Landry, B.S. '97 (Life Scences), D.O. OO;Jessica Paddock, B.S. '99 (Biobgical Sciences); Scott Vaughan, B.S. '99 (Life Sc ences), D.O. 08;John Nadeau,D.O. '04;Amanda Buglio,B.S. '01 (Biological Scences), M.P.H .; Broo~ Azie, B.S. (Medi:al Health Sciences) '01; Jennifer Blair, B.S. '08 (Medical Biology), D.D.S.; Jill Hoffman, B.S. '03 (Biological Scences), Ph.D.;Jason Dugal, B.S. 03 (Medical Biobgw; David Bagg, B.S. '04 (Medical Biology); Stephen Nystrom, B.S. 04 (Bbbgical Sciences), D.O.; Amanda Staiti, B.S. 07 (Medical Biology), M.P.H. '10, D.D.S.; Elizabeth Andrews, B.S. '10 (Chemistry), Ph.D.; Donna Bass, B.S. '10 (Ps}C hobiology); Janelle Blair,

AA'l.n:laStaii p-es~her~atlhe GO.ST<~Shewas .w.rdeda t'ese.r'dl f?l(NIShip t'Orn GO.ST.

B.S. 08 (Med i:al Biobgy), D.O.; Shawn Johnson, B.S. 09 (Bblogical Sciences); Fran Brym, B.S. '10 (Medical Biology), PA.; Megan Mc Burnie, B.S. '10 (Ps}C hology), M.D.;Julie Birch, B.S. '12 (Marine Biology); Leah Tustin, BA. '13 (Psychology); El}'Se Johnson, B.S. '12 (Neuroscience), RN; Eben Larrabee, B.S. '10 (Medical Biologw, D.D.S.; Andre Trzaskowski, D.O. '18; Marina Baran~vitth,B.S. '14 (Biochemistryand Neuroscence); Amanda Quinn, B.S. '14 (Neuroo:ience); Amber Rigdon, B.S.N. '17; Jacklyn O'Brien '17 (Medi:al Biobgw; Harey Neubauer, B.S. '17 (Marine Science); Megan Schanck, B.S. '17 (Med i:al Biobgy); and Samantha Schildroth, B.S. '17,(Medical Biologw.

R1S1HCTIOE I collegeofosteopathic me:licine I 34

I Bridging Critical Care and Neurology for Survivors of Cardiac Arrest DAVID J. MOKLER, PH D., PROFESSOR OF PHARMACOLOGY, CHAIR OF THE DEPART ME NT OF BIOMEDICAL SCIENCES

Teresa May,D.0.'08

Teresa May, D.O., received her medical degree from the University of New England College of Osteopathic Medicine in 2008. She did her interna I medicine res idency at Maine Med ica I Center (MMC), receiving the Intern of the Year award in 2009. During her residency, she became interested in er itical care medicine and began work ingwith David Seder, M. D., and Richard Riker, M.D. From 2011 to 2014, May did a pulmonary and er itica I care tel lowship at MMC, went on to complete another fellowship in neurocr itica I care at Columbia Presbyterian, and then received a certificate in Clinical and Translational Sciences from Tufts University. She has co-authored eight peer-reviewed publications in the area of critical care and is part of an active research program at Maine Medical Center, while simultaneously completing a master's degree in cIin ica I and trans Iationa I sciences at the Tufts Sack Ier Graduate School of Biomed ica I Sci enc es.

May's current research focuses on the influence of sedation and cognitive outcomes in patients surviving cardiac arrest. This year, she was awarded a KL2 grant titled "Variation in Sedation and Neuromuscular Blockade

35 I college of osteopathic medicine I RISING TIDE

Practices on Outcomes after CardiacArrest" and has a separate grant through the Maine Medical Center Cardiovascular Research Institute to study outpatient neurocognitive rehabilitation in cardiac arrest patients.

At MMC, May works with UNE students on various projects. This summer, she and Pasquale Marotta (COM, '19) initiated a study titled "PROspective Validation of sEdation and Neurological Scales" (PROVEN) and a retrospective review of antibiotic prophylaxis in cardiac arrest patients. They are continuing their collaboration throughout this year.

May speaks readily about the importance of student involvement in research, saying, ''There is a big learning curve when it comes to study design, implementation and statistica I methods. Obviously, having more exp er ience early in someone's career would be helpful.

There is a robust student research program at UNE that complements a variety of interests.

I am looking forward to combining the research we are doing at Maine Medical Center with what is being done at UNE."

Up and Coming Researcher: Student Doctor Mark Unger JANEE. CARREIRO, D.O., DEAN, COLLEGE OF OSTEOPATHIC MEDICINE, VICE PRESIDENT FOR HEALTH AFFAIRS

program. As part of that program, Unger worked under the direction of Frank Willard, Ph.D., professor of anatomy, preparing and presenting anatom ica I mater ia Is at nati ona I seminars for interventiona I anesthesiologists and radiologists. During one of these UNE-led training sessions, Unger had the opportunity to work with physicians and researchers from Mayo Clinic. Subsequently, when the Departments of Anesthesiology and Diagnostic Radiology at Mayo Clinic reached out to W iIlard with an opportunity for a student research trainee, Unger was identified as a potential candidate. Now, as part of an osteopathic research fe Ilowsh ip affiliation with Mayo Clinic, Unger is a research trainee in the Beutler Chronic Pain Lab under the supervision of Andreas Beutler, M.D., and Timothy Maus, M.D. In addition to gaining exposure to translationa I res ear ch paradigms, Unger works with mentors in the Neuroradiology, Diagnostic Radio logy, Oncology and Anesthesiology departments to develop clinical skills around MRI and ultrasound interventions, postoperative recovery, catheter ization, sedation, intubation and induction of gen er aI anesthesia. He is also responsible for teaching clinical and biomedical material to the laboratory technicians and personnel and for assisting with the design of cl in ica Ily faithful chronic pain models. When asked about his experience thus far, Unger noted that one of the key ski Ils he hopes to have refined when he is finished with the fellowship is that of" interpreting and applying the cIinica I evidence base to best help his future patients."

When he app Ii ed to med ica I schoo I in Maine, Mark Unger never expected hewould end up in Minnesota, but that is exactly where his UNE College of Osteopathic Medicine (COM) journey has taken him.

During his second year at UNE, Student Doctor Unger was accepted into the Pr edoctora I OPP/Anatomy Fel Iowsh ip Marl< Unger (COM; 18)

..

, liil

.

.

.

UNIVERSITY OF

NEW ENGLAND

â&#x20AC;¢

:.

~

t

:.

TANGIER CAMPUS

i

I

I

Chronic Pain. Motor Output and Motor Learning .in Knee Osteoarthritis t ~Il::LERIH ER UDO L.E'.1::1 ,.El-T,.El::L.D, ,A S.SOCJAlÂŁÂŁRQF..ES.S_OR, DEPARIMENT QF E'.l::IYSl CAUJ::1 EM.PY .

Sitting in a conference room, three students well on their wayto tecomingdoctors of physical therapy

are engaged in a livelydiscussion of what influences human motor control. One student notes, "I th ink we talked a tout this in our "neurd'c lass the other day; is that the same principle?"ltisassimpleas

that, the "ah ha" momentofclassroom learningteing applied to real life. The meeting is a "journalc lub" in

which students rea::I and present research paP3rs from scientific journals to understand the science behind ph}'Sical therapyand engage in an ongoing research project

Tited "Chronic Pain, Motor Outputand Motor Learning in Knee Osteoarthritis,"the research project was awarded an Academic Research Enhancement Award QIREA)from the National Institutes of Health.

The goals of the AREA Program are tosupport

meritorious research, exp:ise students to research and strengthen the research environmentofthe institution.

Directed by Katherine Rudolph, PT, Ph.D.,associate professor in the Department of Ph}'Si:al Therapy, the research investigates whetherch ronic pain interferes with motor learning, which has imp:,rtant implications for the care of P3ople with chronic pain.

39 I westbrookcollegeofhealthprofes:sions I RISINGTIOE

r.llkine ~d:IIP'l, PT, Ph.D. ,rneasU'es pressi.,re pain ~mdds in tle.r'rn bec.ai.ise l4'l8e pain rn~resa.,ltin ligt'ler pah SU'ISiivily <ill OM tie bodt,.

Motor learning involves a complex precess in the nervous system thatcccu rs in response to the practice or exP3rienceof askill. When error in a desired movement is detected, the information is used to adjust the output of the muse u la r S}IS te m to reduce the error the next time the movement is

9'1.Jdents nub c:mnei;ions bel<M?ien bl' dassroorn le.r'ling.~ent c.re e,;iE'S'ien::es .n:I ihe rese.,-dl ihat p-o',tdes -~ ha!""rncrnents tm rnff rese.rch M .nd reW/l'di~

performed. Chronic pain changes the way that sensoryin1brmatioo isdetec1ed bythe nervouss}'Stem, and Rudolph's research investigates whether sensory changes due toe hron ic pain from knee osteoarthritis reduce the abilityto learn new wa}IS of moving. Motor learning is the cornerstone of ph}'Sical therapy,and a thorough u nderstandingof the scientific principles under tying motor earning is vital to physical therapists' practice. The results of the study will be used to develop rehabilltation programs to help people with knee pain to move toth without pain and in W'iJ'/S that mights low progression ofthe osteoarthritis.

and this AREA award provides the means to a:complish those goals."

The results of the study will be used to develop rehabilitation programs to help people with knee pain to move both without pain and in ways that might slow progression of the osteoarthritis.

Rudolph is the director of the Moton Analysis Labat UN E~ Portland campus. She came to UN E in 2011 from the Universityof Delaware where she was an associate professor in ph}'Sical therapy and director of the interdisciplinary Ph.D. program in biomec han Cs and movement see nee. Her mission is to help grcmthe research capac lty in the Westbrook COIie~ of Health Professbns,and involvingstudents is an integral part of the precess.As Rudolph explains, "I love doing research, and my favorite way to teach students is to demonstrate the principles theyare learningand provide them with opp:,rtu nities for discovery. There is no better waytodothatthan through research,

In 2013, Rudolph developed the WCHP Summer Undergraduate Research Fellowship program, which she continues tocoordinate.Arou nd the same time, the Motbn Analysis Lab moved from a site in Saco to the Portland Campus and, as Rudolph notes, "Since that time research and tea: hing in the lab has eo<ploded:' More than twenty W CH P undergraduates have teen in\/Oh/ed in summer research fellowships, workingwith research mentors in the College of Health Professions as well as the Colege of Arts and Sciencesand CdlegeofOsteopathi: Medicine."ln2016,

RISING TIDE I west brook college of health professions I 40

I

I

Rudolph's NIH¡fu nded research project is in the early stages,so resu Its have ~etto te develoP3d; buts he is more than satisfied with the eel ucational outcomes that participatingstudents have a:h eved thus far. As the project progresses, Rudolph is already planning her next grant prop:isal totestan intervention to reduce pain, improve function and slow progression of knee osteoarthritis, and she is alrea::ly lining up students to help in that precess. "It is extremely rare

1br physical therapyprograms at institutions Ii~ UNE to have research facilities Ii~ the Motion Analysis Lab,"she says. "It is verye:xc itingtowork with undergraduates whoa re justst:artingto explore physical therapy as a profession as well as with budd ingph}'Sical therapists in the D.PJ. program, because I know thattheywill ha11e the capacity to thinkcriticallyatout the treatments they provide their patients so that our professbn will continually a::lvance and improve the lives of those in ourcare.'' â&#x20AC;˘ D. P.T. sil.dents tone hir cbse'\>alim<il skms .nd .iw1y pind~es le<l'ned h dass 1:0 acions perict'Md in h MOlion AA<ilysis L.ab

-

O>Jer half of the D.PJ.class, 31 of 59students, opted to participate in a research project,and 11 ofthem are working on my NIH funded research;' notes Rudolph.

In 2016, over half of the D.P.T. class, 31 of 59 students, opted to participate in a research project, and 11 of them are woiking on my NIH funded research-

-

1

- Katherine Rudolph One student who wor~d with Rudolph commented in an evaluatbn that theexP3rience "Realtychallen~d my critical thinking! "while another wrote, "I can't waittocome ba:k in the fall and con tin uethe project" Two of the students contacted her while on their full-time clin Cal internships tod iscuss applying the information theyha::l learned from their research to patients theywere treating in the clinic. That was the outcome for which Rudolph had been hopingtranslating research into clin Cal pra:tte.

AeSN'ch p;,1idp.nt <had L't(lns steps cn10 tie stalicn.ry be1tota 1readrtill, cne Off'le cordi1icns 1Jsed 10 assess

mO\Orleanirt,

41

I

westbrook college of he.a Ith professions

I RISING TIDE

-

--

Supporting Adolescent Adherence in Vietnam MARU.ACl:I MAN D_ESJ.L'l/A, S_C.D~.A DJ Uli.Cl RE.S_EARCJ:LÂŁROÂŁ E.S_S_QB

Emergingtechnologes, includingeectronic drug monitors (EDM), have demonstrated p:,tential as adherence supp:,rts in adults. The SAAV study will extend EDM toadolescents. In formative workduring the first phase of the study, investigators willexamine facilitators of,and challenges to,adherence among a::lolescent ART patients and theircaregivers,d iscuss strategies for improvingadherence and refl neoptions for the intervention. Investigators will also explore with clin t ians their exP3riences caringfor ~uth and managing the transition toadultcare. Usingthis input, they will then tailoran EDM-based real-time a::I herence supp:,rt interventbn.

Mary Bachman De Silva, who joined the Westbrook Colege of Health Professions this June as an adjunct research professor, was recentlyawarded a two-year grant for $345,455fromthe National Institute of Mental Health~ Dwision of AIDS Research. The "Supp:,rtingAdolescentAdherence in Vetnam" (.,AAV) study, just tegun in August, will assess the feasibility, acceptabilityand efflca:yofan innovative approach to improvingadherence to antiretroviral treatment among HIV-p:,sitwe adolescents (at,, 12-15) in vetnam. De Silva will work with an exP3renced team of researchers in Hanoi, with strongsupp:,rtfrom vetnamese officials and clinicians.

In X:.12, there were an estimated 2.1 million global adolescents (10-19 }'ears old) infected with HIV. The benefits ofantiret10>1iral therapy QIRT) haue been well documented. Thus, achievingand sustaining high adherence to ART remain vital to treatment success. Recent data suggest that mortality is rising in HIV-infected adolescents compared 1othe general

In the second phase of the study,a small randomized clinical trial with SO adolescent patients from an HIV clinic in Hanoi will ~nerate preliminarydata on the effica:yof a real-time feed ba: k pac ~ge (which users may P3rsonalize)on a::lherence and clinical outcomes.

The interventbn over six months will measure two forms of a:! herence outcomes: 1) continuous feed back from wireless pill containers via telephone or totl:l&based reminders when doses are missed; and, 2)clinical data from monthlycounselingsessions with ac linician informed by the real-time data.

Comparison subjects will also provide adherence data via wireless pill containers and receive usual care along with an offer ofcounselingat monthlyclinic visits.

Additional quantitatWe and qualitative data will te collected usingsurvey instruments and in~epth interviews.Anal}'Sis of these data will contribute to the currently limited scientific evidence base on ART a::I herence-supp:,rtstrateges in adolescents. The research team exP3cts that findings will have a high p:,tential for p:,ltyand program impact. â&#x20AC;˘

p:,pu tation, makingadherence to ART in this p:,pu lation esP3ciallyc ritical.

In Vietnam, more than 4,300 HIV-positWe children and adolescents are currenttyon ART,and the first survivingcohorts of P3diatric ART recipients are transitioningto a::lu It care. More than 10 percent of these patients are alrea::lyon second line therapy, raising concerns regardinga::lhererce,drug resistance and the ultimate effectiveness of Vietnam's HIV treatment program.

RISING TIDE I west brook college of health professions I 4 2

I

~ ssessing Carotid Artery Changes in Children in the Cardiovascular Health Intervention Program (CHIP)

I

h u LS.c'ilSLCl::l ,2.J:l,D., lxL P,J:L., CJ:IALR. DE~IMEtn OF EXERCJ-3.EAt:l.D SP_QRLf'.EBFO RMANCE.

Cardiovasculard isease (CVD)continues tote the lea:I ingcause of death in our country,and the rise in childhoc:d obesitythreatens to promote premature CVD in our }Outh. The Cardiouascu lar Health Intervention Program (CH IP)was started 1bur}'ears ago at UNE with Paul S. Visich, Ph.D.,as the site primary investigator folbwing grant supp:,rt. The primary purp:,se of the study is to prov tie children with self-awareness and education a tout CVD, in the hope of encouraginga healthy lifestyle.

This past spring, a new test was added to the study

to assess the thickness of the carotid artery, which

These results suggest that phys Cal changes in one's carotd arteryta~ place ata fairlyearlya~ in children with risk factors for CVD. Previous research has observed favorable changes in Cl MT amongotese

shown tote associated with an increased risk of CVD, and, more sP3c iflcal ty, ccrooa ryarte ryd isease,w hie hcan lead toa heartatt:ack The test, which uses ultrasound, is normallycompeted in a::I ults who are suspected of

diabetic children after participating in a ~arlong lifestyle intervention program. The take-home message? If the assessment of CIMT can identify children at a greater risk1brdevelopingCVD, th is could tea very motWatingtool to encourage lifestyle changes in individuals and families.A second cohort

having carotid arterydisease (a form of CVD) that mayrequire surgeryto reduce the riskofastro~.

of children will be tested th is comingspringto validate these results.

The purp:ise of measuring Cl MT in children was to see ifthere was an association tetween CVD risk factors and Cl MT (ie., whether children with more CVD risk factors ha11e a greater CIMl). A licensed

White presented this research at the New England American College of Sp:,rts Medicine in Providence, Rhc:de Island ,duringthe 1'111 of 2016. The research was funded by the Clark Charitable Foundation.

is referred toas carotid inti ma thickness (CIMl), in

a sub-sample of children. Elevated Cl MT has been

sonographer, usinga p:,rtabe ultrasound unit,assessed CIMT of the right and leftcarotd arteries in a random sub-sample of 119 5th grade students in two local elementaryschools. The average age of the students was 10.5 }'ears.

Dan White (Applied Exercise Science, '17) received an Undergraduate Summer Research Fellowshipfrom the Westbrook Colle~ of Health Professions to LTCIMT in t-llmberofCAD RF

056 055 054 053 052 051

as p<DS• p<Dl-

• O llil1 • 2 • 3

Vhlen o:rnparirt <IMT 10 runtier otrisktactts. aposiii~ lhu relalicnmip was obs~d f'rollgh 3+CAD ri* tao:ors

43

complete theanal}'Ses. Results showed that elevated bc:dy mass index (BMI), bloc:d pressure and glucose levels were associated with higher Cl MT. Children identified as obese based on BM I had a greater CIMT than children with a healthy BMI. In addition, higher Cl MT was observed in children with two or more risk fa:tors for CVDwhen compared to children with no CVD riskfactors.

I

westbrookcollegeofhealthprofes:sions

I RISINGTIOE

"I would h ighlyencou rage undergraduates tota~ part in a research o~rtunity,"Whitesaid. "Performing research differs from the classroom te:ause ~u have toenga~ real world probem-solvingskills such as critical thinking. It may te intimidatingtota~ part in research, but I telieve it is essential tostepoutside ~u rcomfort a:ine,esP3ciallyas an undergraduate." •

--

The ChoRo Test of Visual Perception Related to Driving

I

REGJ..BOBHEU, f't!,D., QT_RLL, EAOJA, PRO..EESSQR,_QEeARTul EJH Q&_O.CG_U2AIL01-l.AL.JJ::LERA8Yi

lheo.,mintOTrese.tdltN"l'lle.rns.bruu.1Si"'h<to~.Fh:rnlefttotightJ:1sll.iaDErners,Gn.<bergc...~.Madsm Q\inrnm:I .PeW<toweitll~.n:l l<iraShctWlber';Er (all dass 01201&>..n:I p-oil:Sscr ~ ~nett.. lheir a::uy resM'dl meMCr.

Visual P3rception,orthe ability to interpret visual in1brmatbn sothatonecan resp:,ndto itappropriatelY,

is a vital skill needed for drWing. For ex:ample,driving requires us to determine how far awayanothervehicle is, toq uCklyfmd landmarks, and to recognize obsta:les anddrivingroutes-even in inclementweather.ln the field of rehabilitation,clinicians are often required to assess ac lient's visual P3rceptual skills.

Based on feedbackfrom occupational therapists (OTs) in the community, who said that an adequate assessmenttcolwas notavailable, Regi Robnett, Ph.D., professor in the Departmentof O:cupational Therapy, a numter of master's students in UNE's ccc upatbnal studies program,and alumni develoP3d the ChoRoassessmenttool, which uses photos, figures and concepts related sP3ciflcallytod riving.

Initial psychometrC analysis on hard copies of the ChoRo, given 1o more than 100 adults from the local community,demonstrated that it had promise as a test ofvisual P3 rception and also that it see rred appropriate for on line a:I ministratbn. The ChoRo, which is a UN E-sp:,nsored on line tool, is now available for clinicians at https://unechoro.word press.com. In return for using it, Robnett and her research team asktestadministrators to send in de-identified client data,sothat the test can continue to evolve. This is an IRB-approved research project, and, to date, more than 500 cIi nic ians have visited the site. Further analysis and upjates are planned on a yearly basis.

Reg,,rdingthe experence ofdevelopingthe ChoRo, Kimberly Chon kl, OJ. 01sa}'S, "Having the

Mastr4's0fSdeminO~CM11Y4<Pto~1S¢1ass0f201$)

MadsonE!t\,nrnm:l.nl~Olowwotkcntie<h:l~.hoMne..;s~ ~ tesouatedtlOi'-'~

opp:,rtunity1o workcloselywith fa: ulty, whom I studied underand gained resP3ctfor during my educational exP3rience at UN E, speaks \IOlu mes to the qualityof UNE~ occupational therapyprogram.

Collal:oratingwlth fa: ulty1o helpwlth the research p:,rtion and with clinicians who work in the field on a daily basis is essential to developing research that has functional outcomes 1br our patients.

'1"he ChoRooffers clinicians a new Wa'f of looking sP3ciflcaltyatthe visual P3rceptual skills involved in driving. There are several tests that look at cognitive and visual perceptual skills from c hikl ren 1o a:l ults, but none of them directtycorrelate to driving. Orr.ling rehabilitation is asP3cialtyareafor cccu patbnal therapists,and was brought to my attention after a conversatbn I ha:I with a colleague workingatAlpha One, which provides independent livingservices in Maine. After looking at what tests were currently availa~e toaddressthis concern, we found there was nothingon the market.So, that~when I brought this 1otheattentbn of Regi Robnett. I knew she had develoP3d the 'Safe At Home'testand was wondering ifs he ha:I interest in working on this project. That's how we got the creative idea ofcallingitthe ChoRo, which is short lbr 'Chonko/Robnett:" Among the other alumni that deserve credit 1br their i n\lOlve men t in the p reject from its ear Iies ts tages are Jessica Bolduc, B.S. '04, AmandaAll:oth, B.S. 09, Ja:queline Aldred, B.S. '10, Cassi, Ames, M.S.OJ. '10, Retecca Lindquist, B.S. '09 ,and Laura Wallace, B.S.'10. a

RISING TIDE I west brook college of health professions I 44

I

I

I

'Supermarket Science: Multipronged Approaches to Increasing Fresh, Frozen and Canned Fruit and .Vegetable Purchases i lCl:lELE_E_OLA_C_SEK,E.H.D.,ASSOCJA[E eRQEES,SQE, WESIBRQQK COLLEGE OF.HEALIH PROÂŁE.SSJQNS..

Associate Professor Michele Polacsek, principal investigator (Pl), and Universityof Southern Maine

Research Associate Rebecca eoulos 4:o-Pl)are collaboratingwith Harvard University, the

Un iversityof Southern Maine and the Foo::I Trust of Penns~vaniatocond uctoutcomes research and

change practices to combat chronic disease under a newlyfunded 1bur-}'ear, $8::>0,(XX) grant from the National Institute of Fo::d and Agriculture and the U.S. D,partment of Agriculture.

Few U.S. youth and a::lu Its a:h eve the recommended inta~ of fruits and 11egetables (F&V). Increasing inta~ of F&V and whole grains can helpclose the "energy gap"that has led toe:xcess weight gain among children. Children who consume a diet rich in F&V, low-fat dairy products and whole grains, that is also low in energy~ense, nutrient-p:or 1bo::ls,are less li~lyto be ouerweight and obese than peers who consume more energy-dense, nutrient-p:orfco:ls.

Barriers to healthyeatinginclude the aflbrdabilityand availabilityoffresh produce and other nutrient-dense fco::ls. Research has shown that low-income

45 I westbrookcollegeofhealthprofes:sions I RISINGTIOE

p:,pulations sP3nd ess on F&V P3r P3rson than higher income p:,pulations. Cost, time,convenience, litera:Y, know led~ and skills are major barriers cited to pu rchasingand prep:aringF&Vin Maineand elsewhere.Additionally, maternal intake of F&Vis p:,sitivelyasscciated with children's inta~ of F&V; this, in turn, is inverselyasscciated with child weight status. These data suggest that efforts to increase F&V purchases and intake byadu Its in the house ho kl will p:,sitively imp:actch ildren's consumption and weightstatus.

The large chain suP3rmar~tsettingis an ideal pla:e to help address thea1brementioned barriers.And while nutritional interventions are currentlyof interest to grccery retailers, public health professionals, p:,licyma~rs and federal agencies, there are limited data available using lar~ suP3rmar~tchains. There is also much interest in incentWizingthe purchase of health er 1bo::I items among low-income p:,pulations, instead of restrCting pure hases (such as restrictingsugary bevera~ J>Jrchases with dollars from the Supplemental Nutritbn Assistance Program, known as SNAP).

-

This project uses implementation metho::ls from the highlyeffective,double-value cou p:,n incentWe

The primaryobjectives of the study are to obtain data on: 1) participants' total and relati11e percent of F&V

program used at farmers' mar~ts,as well as the Cooking Matters at the Store eel ucational program (a partofthe national No Kid Hungry/Share Our Strength initiative) to incentWize the purchase and

purchases per shoppingweek; 2) participant-rep:,rted consumption of F&V ;and 3) participants' rep:,rtingof children~ F&V consumption at home. The Fo::d

consumption of fresh pro::I uce,and healthful frozen and canned F&V (withoutsyruporsalt)aswellas nutrient-rich and affordabe year-round alternatives to fresh pro::I uce. Some 600 shopP3rs from one suP3rmar~t location in a bw-income setting will be enrolled and incentivized to use a store byaltycard.

Participants 'shopping ~tterns will te assessed during a two-month baseline P3rio::I te1bre teing randomly assigned to a control arm or toa fruit and vegetable discount plus a CookingMattersarm. The intervention will continue 1br six months and participants' purchases will continue tote assessed 1brthree months p:,st-intervention.

Frequency Questionnaire (FFQ)will te used to assess participants'd etarypr3:tices while suP3rmar~t

The process made me keenly aware of the many barriers that low income 11ainers face in accessing and preparing healthy foods; I'd learned about those barriers while in school for my :MPH degree, but talking with individuals about their experience was eye-opening in a very impactful way. This awareness and experience will certainly shape my future work in the field of public health.

- Zoe Hull checkout data linked to UPCcodeswill be used to track all J>Jrchases.Allthreeaimswill betestedamongallstudy participants as well as amongSNAP-recipients on ty.

This studypresents a unique opportu nitytotestthe effectWeness ofa pricing incentive lin~d toscalabe, p:,intÂŤ-purchaseeducation within a large grccery chain to promote F&V purchases among rural, low-income, high SNAP-usingfamiles. Research findings will help inform food retailer efforts to encourage health er purchases for low-income p:,pulatbnsand help p:,li:ymakers identifystrateges

Alyssa Mmn, adca:irai c.nddate at 1-hMrd Sctod Of Pl.it4ic ~ti ,.nd zoe MUI ,a reSN'ch assistant at tie UN ESdlool ot<onrnUlity .n:I Pop.,lalicn Me<iltl,rea,,,itstowers ata local SIJPE'f'!M'kel

that include toth education and incentivestosupp:,rt regional system drivers designed to reducethe prevalence of obesity. Findings and dissemination eftbrts will contribute to the overall eftbrtto prevent childhood obesity in the U.S. â&#x20AC;˘

RISING TIDE I west brook college of health professions I 46

I

I

Introducing IHS 130: Health Profession First-Year Experience! learning Together for Future Practice Together l AREN J . PARDUE, PH .Q,, Rt{,.AfilE, PRO FESSQR, ..A.SSQCI.Alti)J:j,.filQ R ACADEl,11 C AFFAIRS

saco Ma,µ ~l.nd Mch.ul. UN£ President Donielle r.si:-ch. Fh D. ,.nd E!iddeford Ma,p .oJ.n Olsawfltgi...e a Gale;i,..e lhUllbs·lP at tie seo:nd ~ll.11 UN£ DayOfSIEr',tce.

The Westbrook College of Health Professbns (V'JCH P) is pleased to announce the launch of a new course duringthe Fall 2016semester. lH S 13:>: Health Profession First-Year ExP3rience (FYE) representsa new a:ldition to interprofessional educatbn atUNE and is required rorall undergraluatefi rst-}'ear students majoring in applied exercise science,athletic training, dental hygiene, health wellness and occupational

learningobjectives, identifyingappropriate course content,and creatinglesson plans tosupp:,rt consistencya: ross multiple sections. In the Fall X:.16 term, 18 FYE sections were offered to 3:)6

studies, nursing, nutritbn, public health and so: ia Iwork The course is also a requirement for all students admitted to the pre-pharmacy program.

effectively with flrst-~earstudents. Content for the FYE includes material coveringthe transition to colle~ and academic studystrategies; enhanced self-awareness through the com pletbn of a Myers-Briggs personalityassessment, learningst~es and emotional intelli~nce inventores; guidance on healthycollegiate lifestyes; information about the roes and resp:,ns i bi lities of var bus hea Ith profess bns; and discussbn of how to IWe resp:,nsibly in a global sccety.

The goals of this FYE are to ensure a successfu I student transition to college, provide affirmation of "flt"forastudent'schosen health profession major, tegin demonstrating interprofessional collatorative com ~encies, and fa: ilitate student self-appraisal for optimized P3rsonal decision-makingand the maintenanceofa healthycollegiate lifestyle. The design of the course refects a unique a:ademic/student affairs partnership, involving16 undergraduate and graduate faculty members from WCH P, facu ltyfrom the Colle~ of Pharmacy (COP), representation from the StudentAcadem i: Success Center (SASC) and a coach from varsityath Btics.

Usingawreciattve inquirythecryas a framework, teams of p:artt ipants envisbned the course -designing 4 7 I westbrook college of he.a Ith professions

I RISING TIDE

students bya talented and committed teachingteam.

The team approach includes b~monthly meetings that a lbw instructors tocritique established esson plans and provide mutual support in working

The F'YE incorporates high-impact, a:twe pedagogi:al pra:ttes promulgated by the Assa:. iation ofAmerican Colleges and Uni\!ersltes QIAC&U). Learning a:tWities in thecourse highlight the Inter professional Collaborative Competencies OPEC, 2016), proua ing students with opp:,rtunitiesto learn atoutand pra:tice effective communication, 1eamwork,confl ct resolution and knowed~ of health profession roles and resp:,nsibilites. The course is anchored bya common

·~

JL

·- -

reader: lllis IBe/ie,e; Personol Plv/osop/ves of 11emorkof>le Men <>'ld \M>men Qlllison, 20:>6). Thistextlxx,kpro,aes a plat1brm for students to exc han~ diverse ideas, vewp:,int:s and ex~riences as well as furtherclarify their own thoughts and beliefs. The pedagogies described above are intentbnally interwoven, addressinga contemp:,rarychalenge in higher education to enhance student development of "sottskil~"wlth in the 1brmalc urri:u la QIAC&U, 2015;1PEC, 2016; Pew,2016).The inclusbnofeffective communication, teamwork,confltt resolution and appraisal of self provides a strong underpinningfor sustained a:a:lemt and career success (A.AC&U, X:.15).

A comprehensWe evaluation plan has teen created

to assess the outcomes and institutional impa:tofthis FYE course. Approa: hes inc Iude the review cr reflective essays byFYEstudent:s,student participation in a Dayof Servte orcommunityservte,tivt enga~ment assignment, parttipation in a human patent simulatbn activity, student eadership of a This I Believe rea::1 ing group and authorship ofa This I Bel.ieve p:aP3r. Indirect assessment metrics include cohort analysis of grade p:,int averages (GPA), retention rates and timely graduation rates.At the conclusion ofthe course,

UN£ Assodate D9'110rAcademic A~rs W<illaoe M.rsh, Fh D. ,.n:1 lis FY£ dass pose before he.adngoot en b DayOfSU'\1ce. P.r1idp;nts m:rn h<lass0f2020indlde~pn:,.,.i) JIJia Ft\6:<lk(NJrsirt, '20). ~rm L\flch (NU'Sing;2a,, Elllily M.te01.D( (JllJrsirt, '20). ~ i <ortpqia(P\blic Me<ilfl, '20). Madeline Gen:lron ()-le<lltl, wenness.n:I ooo.p~en<11SUies.'20).nd<Gi11in ~(N.l'Sing,'20)..n:1(1h:ntrON) ~•ey M:X:oHett(N.l'Sing, '20). Fh:ntright w<111aoe Mif'sh, Fh D. ,dilical as:sodate professor .n:I as:sodate de.n 1Ct' AcadernicAffGirs <<OP).

students will complete a First-Yeor Experience Questionnoire (Krause & Coates, X:08) capturing self-rep:,rtdata addressingthe transition to college, studystrategies, peer relationships,enga~ment with fclcultytt:aff and campus-wide engagement.

Future plans include the integration of sophomore ~ar"peer tea: hers"as Cljfa:ilit:ators and course leaders alongside facu ltywhen the FYE is offered again in Fall 2017. • REFEREN:ES: Assochd:n Of kl'lert.n co •ieaes & Uliv8'S ities. (2015) ~11~ shcn? co 11ege ieam ~ ard career si.,coe:ss. Reu" ieved 1l"Orn :ht1Ps:.owv.w. aao.,.oratieap.lp1Jb 1.:-cp h kln-rese.rdl/201S-s1Jrve,,.fa Hha-shon AssochtOO Of kl'lert.nco1ieaes& Uliv8'Sities. ti.d)Hi£1'l·irtpact edll::atOOal practbes. Rtt ilh~d 1l"Orn: htlPS;/,W.,.,W.aaCIJ.01'8/le..p,oh l)s hwp-otess klnal Ed1.1:atien co lhborat~~. (2016) ccre mrnpwsicie:s fer hwp-otessklnalpracta:An1Jpdai::e. Ae1rie)Ed f'crn:ht,p;,',w.,.,w. aaaindle.edwe:lllcatkln-resruroe:s/1 PEC·2016-Ll)dated.Core.cornpewicie:s· Reportpdf

ltause. KL,&Coates, tt (200$Sulen,s'e~gallem hflm•year Ul~~rsity.Assessrnem& &allatkln h Hi£1ler EdJcatkln, ~~).

493-505.

Ptw Aese.rdl cem:er. (2016) 1hestai:eotAA'leria1n ,>bs. Reu-ilh«I fl"Orn: htlP ~w.,.o.pewsoda1ttrds.ora/2016/10,l06/,he·mte-of ¥1'1Er t.n-J) bSI

Madsen Bao:n(Pre-Pl'wl'l'la0t'.'2Qlard 1<Hswic.-1;s1e(De~ ~iene,'20)checkp1,pill.ty re.acion v,Uh Assodate R'otessor Of NJrsi"' D.N.ne- Maie C...rb.r in .n inlrodl£\O'ysirnlJ~on e:.erdse.

RISING TIDE I west brook college of health professions I 48

I

lnterprofessional Research Collaborations to Improve .Outcomes in Athletes Post-ACL Reconstruction

I

路~

JL

路- -

t RlliJ:lAlilLGAN ,JIT,__el:l ,D.,.AIC,..Q CSAS_SQCJAIE PRQF.ESSQR, D.EeAATM ENT QF..EHYSLCALIJ::LERAPY

UN E researchers Erin Hartig,ln, D.P.T., Ph.D.,ATC, associate professor of physical therapy, and Michael Lawrence, M.S., MotionalAnal}'Sis Lab manager, have teamed with orthoP3dt surgeon Thomas Murray, M.D., and physician assistant Bernadette Shaw, PA-C, l:oth from OrthaAssociates (OA) Centers for Orthopaedics, to improve outcomes for individuals sufferingfrom knee injures, spec iflcallya rupture of

equipmentgain a tetterconceptualization of joint lbrres. Since towingasled with 20 perrent tx:dyweight increased knee 1brces in healthy individuals, students hypothesized that th is weighted gait task wou kl he Ip ind iv cl uals after A CL reconstruction. However, it proved tote ineffective,as individuals with ACL reconstructbn used their hiptocomP3nsate instead of increasing1brces in their ACL-reconstructed knee.

the anterbrcruciate ligament (ACL).

As these researchers and students 1brged on, they discovered that athletes did increase the 1brce in their ACL- reconstructed knees while towing the sled and wearingaweighted vest loaded with ~ percent to:ly weight com pared to normal walking.

Though many individuals who rupture their ACL undergo reconstructive sur~ry, not all return tosp:,rt:s.

Manycontinue to favor their A CL-reconstructed limb,creatingdifferences when they return to athletic tas!G and even when they walk normally. Limb differences, partt ularlypoor 1brce pro::luctbn in the ACL-reconstructed limb, reduce theabilityto return to sp:,rts and increase thee hances ofreinjuringthe knee.

This research project real! y allowed me to explore the depths of what physical therapists can provide beyond treating patients in a clinic and to understand how we can provide knowledge to

For more informatbn a tout this study, please see the full research report published in the September 2016 edition of Sports Heolth: A /vi u/tidisciplinoryApp-ooch.

Interestingly, otherstudents in the Hartigan lab lbu nd that tte 1brce increase in the recons true led kneed uring these two weighted tasks was still less than those in the individual~ "healthy' limb. This persistent limb difference may increase the athlete's riskof re-injury;so wa}IS to restore lim bs'Yffi metryare needed. Recently, three 2016 D.PJ. graduates found that specific muscle

P3rformance measures influence knee forces during the weighted sled and vest tasks. They also found that these measures were unique for men and women,

others through our research.

- Morgan Wilson

This groupofresearchers has teen studying the effectiveness of usingweighted gait to increase forces in the ACL-reconstructed limbto ultimately improve knee function after ACL reconstruction.

This interprofessional team has engaged UNE students in its research as well. Researchers help students integrate concepts learned in theclassroom, create hyp:,theses of how to improve function, and then test their hypotheses usingstate-of-the-art motion analysis equipment.

Since joint forces cannot be seen, it is difficult to determine whether individuals are walking normally after an ACL injuryand reconstruction. Students who measure force data with UN E's motion anal}'Sis

49

I

westbrookcollegeofhealthprofes:sions

I RISINGTIOE

Din Collins, D. P.T. 路15, Jcrnes lbv.nsiend, D.P.T. '15 ,.nd Kaiiin Ftlv.e-s, D.P.T. 路15 ,galher at UNE's Ff\,sical lher.ipy Dep;,1mE'f'lt'S 2014 Re:sN'Ch .nd Sdld.r'ship ~

<las:s Of'1 7 D.P.T. n.deni:S ~e Midollsen, Mct'g<Yi \'f\lscn (btJi"' tie sled).n:I Staiciey i,t,.,.,ard .re piloting tie Sled-~ng Wk 10 fe,j tow tie drae:ging ferces aeated ~ tie s1ed aiw tie e«ort re:ilired at tie ltte corrp.red 10 rorrnai wakl~

sug~stingthat men and women should te treated differentlyafter ACL reconstruction. These fl ndings were presented at the 2016American College of Sporis Medicine Conference.

Motion Anal}'Sis;'at the 7th Annual World Congress of Biomechanics in X:.14.

• Sarah Lamberton, B.S. '15 QIJ:l)lied Exercise See nee) presented her poster, titled "AssessingM uscle

Notonlyare D.PJ.students included in the research

Activityd uring Normal and Challenging Walking

which uses state-of-the-artequipment, theyare proud to generate novel information to gu tie test practice

Tasks After ACL Reconstructbn;'at the New England

to help individuals improve outcomes after such a

American Colle~ of Sp:,rt:s Med tine Conference in 2014. Lamberton also Cljauthored a publication

devastating injuryand major surgery. Undergraduate stu::lentsare alsowelcorre to p:artici~te in researching outcomes after ACL injury.Hartigan advises UNE

ofthe Functbnal movementScreen,"whth apP3ared in the February X:.15 issue of lCAver Extremity

undergraduate students who receWe WCHP Summer Felbwshipstip:rnds, which advances her research whie givingstudents the opportu nitytoexP3rence laboratoryresearc h firsthand. Since the inception of

the fellowship in 2014, each undergraluate student has disseminated his or her findings at professional conferences and via P3er-reviewed pu blicatbns: • Jonathan Lester, B.S. '14 (Appled Exercise Science) presented his p:ister, tited "Precise Mar~r

with Hartigan and Chimera, titled "Clinical Utility

Review MO$'Zine.

• Current undergraduate Anna Michaud (Applied Exercise Sciences, '17) received the 2016

Undergraduate WCHP Summer Fellowshipand worked with the research team in the Motbn

Analysis Lab. Her findings will be presented abng with those oftwoc urrent D.PJ.students from the Class of 2017,Abbey Karns and CarlyKeafer, and

Placement Produces Good Int~ and Inter-rater

those of Adrienne McAuley, D.PJ., M.Ed., OCS, FAAOMPT, at the annual Ameri:an Ph}'Sical

Reliabilityof Lower Extremity JointAnges During

Therapy Association NEXT conference. •

RISING TIDE I west brook college of health professions I SO

I

I

Identification of Academically At-Risk Accelerated Bachelor of Science in Nursing Students to Support Development of Strategies to Promote Academic Success DEBRA KRAMLICH, PH.D.(C), RN, CCRN, CNE, ASSISTANT PROFESSOR OF NURSING JUDITH BELANGER.RN, M.S.N/ED., CNE, ASSOCIATE PROFESSOR OF NURSING DANA LAW-HAM,PH.D., RN, FNP,CNE, ASSISTANT CLINICAL PROFESSOR OF NURSING NORA KREVANS,M A., LEARNING SPECIALIST, STUDENT ACADEMIC SUCCESS CENTER Assistant Professor of NursingDebra Kram lich, Ph.D.,and hercolleagues were recentlyawarded a Scholarshipof Teaching and Learning mini-grant from the Center for the EnrichmentofTeachingand Learningto identifya:ademic factors that may put the

accelerated second-degree baccalaureate nursing(ABSN)studentat risk of program competion failure. The results will te used

students whoalready possess a BA. or S.S. and have met prerequisite requirements. The first cohort of ASSN students was admitted in the springof 2012; four cohorts have nCNI completed the program, with a fifth currently enteringthe second semester. Sincethe first class was admitted in X:.12, the program has doubled in size and is expbringfurther

UNE Researchers Investigate Head Impacts in Men's Lacrosse and Men's and Women's Ice Hockey

expansbn.Although the a:ademic strength of the ABSN students is increasing, attrition ratescontinue tote a cause 1br concern.

JOHN M. ROSENE,D.P.E.,ATC, CSCS,ACSM EP-C,ASSOCIATE CLINICAL PROFESSOR, DEPARTMENT OF EXERCISE AND SPORT PERFORMANCE

An admissions test provaed by the UN E nursing program's contra:ted standardized testingvendor,considered to be a test practice in nursing, is designed tote used as a pre-ad mission assessment oras a p:ist-entryevaluation for identification of at-riskstudents. The admissions test was administered as a pilot to the c urrentABSN cohort du ring the firstweekof the program in January X:.16. Du ring the flrstsemester, fa:ultyidentified possiblecorrelatbns between admissionstestscoresandcourseexam grades, partic ula rly among s truggl in gs tu dents.The team antici~testhatexamination ofthisdata may reveal p:,tentially mo::liflable factors that put students at risk of non-progression or d ism issa I and that ide ntiflc ation of such factors maythen supp:,rtthe devebpment of targeted indivD ualized interventbns to promote success.

tosupport the de11elopment of strategies to promote academic success.

resulted in a more diverse student profi e in terms of age,gender, race and eth nicity,and life experience than tra::litional entry-level nursing programs usualtyattra:t. Some studies have reported higherattrltion rates for ASSN students than 1brtra::1 itbnal entry-evel nursingstudent:s,and this attrition is related

signiflcantfccus than ever te1bre. With the d iscoveryof chronC traumata: encephabp:athy (CTE) and the settlement between the NFL Players Associatbn and the NFL with regards to cone ussions, there is increased interest in u nderstandingthis injury.

Researchers John M. Rosene, D.P.E.,ATC, and Paul S. Visich, Ph.D., M.P.H., ofthe Department of Exercise and Sp:,rt Per1brmance, have been examiningsp:,rts-related concussions beyond the gridiron. Rosene and Visich are examiningthe inc Dence of cone ussions in men's and women's collegiate ice hcc~yat the Division I and DWision 111 evels over the past five seasons. Th is research has ~elded several interestingfl ndings, such as a higher inc Dence of cone ussions in Division I versus Division 111 men's ice hockey; a higher rate of concussions in forwards versus all other p:isitions; and most interestingty,a higher rate ofconcussions in women's Division 111 goal es versus a II cthe r goalies. The results of th is study will ead to valuable insight intoconcussbn

The rape proliferation of ASSN programs to a::ldress the critical nursingshortage has

to both academic and non-a:ademic factors.

Sp:,rts-related cone ussions have teen a growingconcern in recent years. With more P3ope particip:atingin sportatall levels, athlete health and safety has become a more

managementand prevention strategies in colegiate ice hockey.

Deb'a 14'.ntich, Fh D. ,as:siswrt p-otessor otmrSing.stows

sEnior rursirt sUEnl:S aresoU'ce torpalient teadlirt.

The UNE ASSN program is a fast-paced, 16-month ,second-degree program for

S 1 I westbrook college of he.a Ith professions I RISING TIDE

Additionally, Rosene and Visich,alongwith applied exercise science students, used head-impact monitors to collect information on the num terand force of head impacts during lacrosse practices and games. The

outcomes of the studyfound that lacrosse pl~rsexP3rence asimilar numberof hits and force of hits to the head in l:oth practices and games. However, none of the hits measured were signiflcantenough to cause aconcussion.

These resu Its suggest that lacrosse players are susceptible to reP3ated head im~ts in toth games and pra:tCes.

FA OTA, has partnered with Spurwink:s O:c up:ationallherapy Services, which is ed byAnna Brown, M.S. '12, OTR/L,tostudy the useofsensorystrategies as an alternative to behavior interventbns in thedaytreatment setting. Spurwink,a nationallyaccredited nonpufitorgan ization, provides behavioral health and educational serve es throughout Maine.

In addition to Loukas and Brown, the research team includes Professor Regula Robnett, Ph.D., OTR/L, FAOTA, Tina Champagne, OTO, OTR/L,and Nathaniel Fu lier, BA. The occupational therapystudent researchers include Class of 2017 members Kelcey Briggs, Kelly Doiy,,k, Calley Rock,Arynne Siple and Aleo<andra St. Clair.

This collatorative research project includes the entire staff of Spurwink's sixsP3c ialpurp:ise schools in an effort to change the paradigm of mental health interventions for chitlren and youth with significant behavioral challenges. Spu rwinkwas awarded a grant by the Davis Family Foundation to implement sensory rooms at each school location and to begin the study. The SensoryStrategies Study includes natbnal consultant Tina Champagne, O.T.D., OTR/L, Spurwin kadministrators, mental healthwcr~rs,oo:upatbnal therapists BliomeTl.l'Cotte Q)p~ied ÂŁ>Erdse Sdenoe,'1 7) p-epns 1:0

hita Soo::e' b.:tl v,Uh her head 1:0 galher re<Mlrne data en h fOn::e Offle inpact.

Self-Organizing Sensory Strategies Promote Occupationa I Performance KATHRYN LOUKAS, O.T.D., M.S., OTR/L, FA OTA, DEPARTMENT OF OCCUPATIONAL THERAPY,WCHP ANNA BROWN,M.S.'12, OTR/L, OCCUPATIONAL THERAPYSERVICES, SPURWINK Atone social servCe agency, ~u might see youngclients tossing a medicine ball,jumping on a min itramp:,lineor using mindful coloring activities instead of sittingalone in an empty space. Clin Cal Professor of Occupational Therapy Kathryn Loukas, O.T.D., M.S., OTR/L,

and students and faculty from the UNE Occupational Therapydepartment. The team has created sensorystrategies to su pp:,rtchildren with autism and mental health challenges in the day treatment setting. These strateges can be utilized when the children are feelingoutofcontrol and are, therefore, fl nding it more difficult than usual toenga~ inc lass room learning.

The proj?ct uti Iizes a dynamical S}IS terns-based approach grounded in the Reco,ery Model to create and implementtraum~informed ,selforganizingsensorystrategies tosupp:,rt occupational P3rformance, posit We behavior and self-regulation. 0cc up:ational the rapists at Spurwink implemented thesensorystrategies to meet the needs of the sP3c iflc p:,pu lation or individual th rough the use of a sensory room, cart, sensoryactivities,"d iet,'br other safe and self-selected environmental enhancements aimed at helpingclients mo::1 ulate their own ner""us S}'Stem. Westbrook COIie~ of Health Professionsoccupational therapyfclcultyand students supported the proj,ct bydevebping, impementingand anal'Y7ingoutcane rreasures of th is twlj~ear project.

9'1.Jdent Ae:suchers casey ~ck(OOOJ~oM 1'1Y4'.ipy.

'17),Pl''tf'rle st~e (000,,palicna lhEr.ipy.¡1 7). ~oey E'tiggs ~oo.palicnGI lhEr<Pt','1 7), !<Elly Dayal< ~oo.palicnGI 1'1Y4'<Pt'.'17>.n:IMeauhSt<lair~a,.p~oMlhet<Pt'.'17>

Outcomes a World Away!

JENNIFER LEE MORTON, D.N.P., M.P.H ., APHN-BC,ASSOCIATE PROFESSOR, DIRECTOR, DEPARTMENT OF NURSING R. DENNIS LEIGHTON, P.T.,D.PJ., ASSOCIATE PROFESSOR.DEPARTMENT OF PHYSICAL THERAPY For several ~ears, UNE students and faculty haveenga~d in a cross-cultural immersbn program with the Ghana Health Service (G HS), the Universityof Gape Coast (IJCC), the private sectorand, most imp:,rt:antly, the communities surround ingSekondi in the Western Regbn of Ghana.

The trust-based relationship has now evolved to a new level with measureabe outcomes accordingtothe Triple Aim

RISING TIDE I west brook college of health professions I 52

• UN Estudents are now a part of the ongoingquality improvement realized in this cross-cultural learningexchan~.

Initiatives that have teen Cljgenerated from student ideas toward clinical improvements include: 1. Refined clinic in put card with co::ling 2. Out-take precess that serves as a feedback loop toensure all care needed Arursi"' sUentpErlerms a rn<11<11a tenon apalientin

was received

Slt?klrdi Oinic.

3. Tra:king malaria rapid p:,int-of-care

Framework. '1"riple Aim" refers to the three goals of the program: improved population

testingand outcomes

4. Mo::lifled communityassessments

health, lower costs and p:isitive patient exP3rence.

5. Monitoringexercises prescrited by physiotherapy

The followingdevelopmentsdemonstrate the progress we have made:

6. Tra:king return-to~ linic outcomes

• Demographically, in '.X:l14,our reach was in Sekondi and Kansarafo. By 2016, our rea: h extended to two more rural communities: Mpintsin and Diabene.

The Universityof New England has recei'led fund ingand currently has nine trainees who are being mentored in Leadership Education in Neurodevelopmental Disabilities 0.END).

LEND programs are established to train future

• In 2010, we were fortunate tote joined in a learningexchange by two doctors and

the Ukraine; and a pharmacist and two pharmacytechnicians from the private sector. Collectwelytheysaw 902 patients.

UNE ~dents.fdOJlty .n:I OOl"l'rnUlityhe¥1h v.otm's oeiebrate lheir SllXle:Sffl.11 omtk 1:0geta'.

inter professional eaders to improve the health and well-beingofc hitl ren who have, or are at riskofdeveloping neurodevelopmental disabilities sue h asautism, cerebral palsyand intellectual disabilities. The Maine LEND program is partofa networkofprograms throughout thecountryfunded by the Health Resources and Services Ad ministratbn's (HRSA) Division of Maternal and Child Health.

This five-year, $2.2-million grant and the associated curriculum was develoP3d and is being implemented through the lea:lersh ip

1nb3'p-otes:sicn<il g,'OlPS Of ~dEnts pErlerrn 111• in Slt?kmd Clilic.

53 I

EILEEN RICCI, PT, D.P.T., M.S., P.C.S., ASSOCIATE CLINICAL PROFESSOR, DEPARTMENT OF PHYSICAL THERAPY, MAINE LEND PROGRAM DIRECTOR KATHRYN M.LOUKAS,OJ.D, M.S.,OTR/L, FAOTA, CLINICAL PROFESSOR, DEPARTMENT OF OCCUPATIONAL THERAPY, MAINE LEND TRAINING COORDINATOR

• In 2011, in philosophical alignment with our Ghanaian partners, we started a longitudinal prosP3ctive sc reeningfor outcomes, and we started contributingto the cost of an annual insurance premium ratherthan paying for needs on an individual basis. A 1otal of 122 patients were insured through this framework. In 2016, more than 340 ind widuals a: ross fou rcommunities were insured th rough this framework.

two nurses from the GHS. In 2016, we were joined bythree physt ians, two n urses,an optometrist and herstaff,and a physiotherapist, all from the UCC; a ph'YSician,a physician assistant and a nurse pra:titioner from the GH S;a med i:al student from Sekondi studying in

The Maine Leadership Education in Neurodevelopmental Disabilities (LEND) Program: Making a Difference for Children and Fam iii es in the State of Maine

westbrookco11egeo(healthprofessions I RISINGTIOE

of Program Director Eileen Ri:ci, PT, D.PJ., M .S., P.C.S., associate clinical professor of physical therapy,and Training Coordinator Kathryn M. Loukas, 0.T.D., M .S., OTR/L, FAOTA,c linical professor ofccc up:atbnal therapy. Familyinput,as well as grant

administration supp:,rt, comes from Peter

El is deft ned asa setofemotbnal and social

Herrick, M.S. Ed .,assistantd irector of

skills that influence the way we ~rceive and expressourselves,developand maintain social

Sp:,nsored Programs at UN E. Alison Barker serves as the administrative assistant.

The UNE group is workingwith practitioners from Maine Medical Center and associated

Screening Graduate School Applicants for Emotional Intelligence

relationships, co~ with challen~s and use emotbnal information in an effective and meaningful way.

clinCsto ma~ a difference in manyaspects of

Iife for }OU ng people with neu rc:deve bpme ntal disorders and their families statewide. The Maine LEND program received fundingon July 1, '.X:l16,and will continue with a new

grou p of trainees, fellows and p:,s t-da: tora I felbwsevery~ear forflve~arsasthe ~ogram builds. Program goals include increasing interprofessionaltrainingin autism s~ctrum disorder and other ne uro::levelop mental conditions; increasinga:cess to intervention and support; en hanc ingclin ical ex~rtise and leadership of practicing professionals; research su pp:,rt; strengtheningcommu nity links and access; and a::ldressingthe needs of underserved p:,pu lations.

Other UNE t..cultyand mentors involved in the program include: Kira Rodriguez, M.H .S.; Audrey Bartholomew, Ph.D.; Shelley Cohen Konrad, LCSW., Ph.D.; Christine Ro~rson, LCSW; Valerie ..bnes, LCSW; Jennifer Morton, D.N .P., R.N.; and Karen W..dman, D.N .P., RN, N NP-BC. For more information on the Maine LEND

program visit: http/t,,ww.u needu/LEN D

LEND LeaderslipgrrupO,Ontrow,l:R) Kall"r,.n t.rukas,

ALLISON MORRILL,J.D.,PH.D., INTERIM ASSOCIATE DEAN FOR RESEARCH, WESTBROOK COLLEGE OF HEALTH PROFESSIONS KAREN T.PARDUE,PH.D.,RN,CNE,ANEF, ASSOCIATE DEAN FOR ACADEMIC AFFAIRS.WESTBROOK COLLEGE OF HEALTH PROFESSIONS,ANDASSOCIATE PROFESSOR OF NURSING

El is detned as aset Oferoo1im<il ard sod<il skl11s lhat inRllen::e lhew~'M? peroeive .vld e:.;tess rurselves, develcp

SCOTT D.MCNEIL, 0.T.D, M.S., OTR/L, ASSISTANT CU NICAL PROFESSOR AND ACADEMIC FIELDWORK COORDINATOR, DEPARTMENT OF OCCUPATIONAL THERAPY

.vld mn~n sod<il relalionslips,oope 'MIil ch<111~s .n:I llse emOlioM infOrrnalim in .vl effel;1ive .vld me.nngt,I ~

MARIBETH L.MASSIE,CRNA,M.S., PH.D. (Q,ASSOCIATE CLINICAL PROFESSOR AND PROGRAM DI RECTOR, MASTER OF SCIENCE NURSE ANESTHESIA PROGRAM

professbnal ~rformance. There are two parts

RHONDA FELDMAN, M.H.S., MSS,PA-C, ASSISTANT CU NICAL PROFESSOR AND PROGRAM DIRECTOR, MASTER OF SCIENCE PHYSICIAN ASSISTANT PROGRAM In 2016, UN E's graduate programs in nurse anesthesia, ccc upational thera pyand ph}IS ic ia n

resu Its on students' long-term a:ademic and

to the studysdesign: 1)acomparison between the performance of students admitted after El screen ingbegan and the ~rformance of students a::I mitted in previous years; and 2) a comparison amongstudentsadmitted in '.X:l16 and after, lookingforasscciations tetween ~rformance and El score.

Outcomes tote examined include gra::le point average, probation or marginal status,

assistant in the Westbrook Colle~ of Health

~rformance on simulated p:atientencounters

Professionsadded a new element to their a::lmission precesses.Appl Cants werescreened

or pra:tical exams during latoratorycou rses,

for Emotional Intelligence (El) usinga

su~rvisor assessments in clinical settings, on-time degree completion,and passing toard

combination of interview questions, writing

exams on the flrstattemptor with in one year

samples and/or role playactivites s~cially

ofcompletingthe program. Investigators will

tailored forea:h program byeo<pert

also examine q ual itatWelyw hethe r the reasons

consultant Korrel Kanoy, Ph.D., of Developmental Assa:iates.A fourth graduate

for less than optimal ~rformance are related to the erootionaland so:ialskillsthatcomprise

ircgram, Jn}'Si:altherapy, collected El data

El. Resu Its will help the Westbrook College of Health Professions determine whetherto

o.,: D., 1r~ni"' ox,n:liM\Or. &1een r.soo, D. P.T. ,P'CV'.rn

from applicants butdtl not use that information

dire;tt~())ad< row, I: R) Alison B.r'ler, fflilis1ralive

to inform its a::I mission decisions.

asSiswrt,.oJ~<r~g.MD.,ot~ne ~deal Rf'1'Y4's¡ F'eji~cNerdogy..n:I Peter ttlrrick,MS. Ed.,as:siswit dire;ttotSpmsored Progr.rns

Fa:ultyfrom each program have now tegu n a

collal:orativesbJdyofthe impactof El screening

expand the use ofscreeningfor El into the admission precess for its other graduate

health profession programs.

RISING TIDE I west brook college of health professions I 54

I

I

Changes in Hydration Status during Pre-Season Training JOHN M.ROSENE, D.P.E.,ATC,CSCS,ACSM EP-C,ASSOCIATE CLINICAL PROFESSOR, DEPARTMENT OF EXERCISE AND SPORT PERFORMANCE Hydration evels may im pa:t P3rformance in numerous ways. Specifically, lackof adequate h}d ration has been shown 1o impair athlete abilites in areas such as skill P3r1brmance, endurance capa:ity, muscularstrength and cognitive function. When in a dehydrated state,athletes haue been rep:,rted 1o need longeramounts of time to P3rform sP3ciflc tasks compared to when exP3rencing normal h}'dration le.els.Additbnally, deh}'dratbn may result in slower decision-makingability.

Preseason camp, which follows off-season train ing,commonly includes multipe sessions per day of high intensityactivity. In addition to these m ultiplesessions,activity may te of a higher intensitycompared tooff-season trainingdue to the tyP3 of exercise and duration of practice sessions.An increase in

re lat We to heat illness and will,subsequently, improve P3rformance.

Increasing the Public Health Nursing Workforce JENNIFER LEE MORTON, D.N .P., M.P.H., APHN-BC, ASSOCIATE PROFESSOR AND DIRECTOR OF NURSING JUDITH A. METCALF,APRN,BC, M.S., CLINICAL ASSISTANT PROFESSOR OF NURSING KAREN T. PARDUE,PH.D., RN, CNE, ANEF,ASSOCIATE DEAN FOR ACADEMIC AFFAIRS, WESTBROOK COLLEGE OF HEALTH PROFESSIONS,ANDASSOCIATE PROFESSOR OF NURSING The Universityof New England Department of Nursingwas recently awarded a Nurse, Education, Practice, Qualityand Retention HRSA award 1o increase the Public Health NursingWorkforce. UNEconcursthatoptimal

initiatingph}'Sical a:tivityand subsequently, toappropriately replenish fluid loss after

~ I College of Nursing~ "Upstream Nursing'' mo::lel that recognizes the p:,werfu I role of nurses in creatingthis meaningful paradigm shift within communities.

John M. Rosene, D.P.E.,ATC,clinical associate professor in the Department of Exercise and Sp:,rt Performance, alongwith 12 applied exercise science and athlete

I

westbrookcollegeofhealthprofes:sions

community-based clinical sites at Greater Portland Health's (GPH) fivec lin i:s and involves the following five objectives: 1. UNE~ DepartmentofNursingde.elops and integrates a series of didactic and community-based clinical curriculum advances designed to increase the capacity of new nursing graduates to practice in community health primarycare settings.

2. UNE~ Departmentof N ursingestablishes a community-based partnershipwith GPH

the inte ns ity of activ ityc onseq ue ntly pla: es a greater ph}'Si:al demand on the athlete.

When this increase in intensityof a:tivity is combined with the summer climate, environmental risk factors may te increased.

Therefore, h~ration levels ofpreseason athletes tecome esP3ciallysigniflcant. In an eftbrt to avoid exe rtiona I heat illness, it is imp:,rtant1o be adequately h}'drated prbr1o

ea: h activitysessbn.

SS

trainingstudents recentlycompleted an investi~ion into how preseason camp affects hydration status ofathletes. The athletes were evaluated teforeandaftereach pr3:ticeduring the preseason for chan~s in weight and h~ration. The information gained from this investigation will lead to protccols that will aid in improuingathlete health and safety

com mun ltyhealth is bestachie.ed through health promotion and prevention ratherthan disease treatment. UNE's nursing program design is thoughtfully informed by the UK

UNE's strategy in this a:ademic/practice partnership is to provide senior-level nursing students with meaningful experiences in

I RISINGTIOE

and its clinical sites that promotes the knowledge,skills and attitudes of community-based learningfor students, while improvingthe health ofclents.

3. UNE will rec ruita total of 12senior-evel nursingstudents to partC ip:ate in the Upstream Practicum.

4. UNE~ DepartmentofNursingand GPH will provide the Upstream Practicum toa 1otal 12 students.

5. UN E's Department of N ursingexpands its Nurse Leader Institute toa statewide consortium that includes sen br-level stud3ntsenrole::I in the Upstream Pr3:ticums.

Jennifer Morton, D.N.P., M.P.H .,APHN-BC, serves as the project director for the program while Jud Ith A. Metcalf,APN-BC, M .S.N ., will coordinate the partnership pra:ticums with Greater Portland Health.

Karen Pardue, Ph.D., associate dean, WCH P, will coordinate the Populatbn Orientated Nurse Leader Institute, which continues from the CHANNELS proj,ct.

u.ne~l 8.S. '15 pridpatesina F11.1Clilic.

~ 81n .,..,,,.,,Os.•,s.,, c,s,.,,,.,m,.,...., 15 «>•-•cro""•·'"' .,.,d..,.ons<r.<onOf""''"'°"'°" R1S1NCTIOE I collegeofpharmacy I 58

and the students haue been v.orkingtowards: (1) K-12 educational outrea:h efflcacyoutcomes, and (2) UNE studentsuccessoutcomes.

This pho1Dof Sam EsPJSito(l}'Seth Elementarystudent) and Erica Paulette (Pharmacy, '16)was taken during the 2015 STEM Exp:,. This activity, which centered on brain reward pathways,was presentedtomanyK-12 studentsooerthe courseoftheday.Although this time and effort was well sP3nt, tangible outcomes that might supp:,rt the "efficacy• of this educational a:tivitywere notcollected. In fa:t, there is a paucity of evidence in the literature that has documented K-12outrea:h efficacy.

Hence, a recent UN E-driven studyadministereel a cannabinoid educational intervention among college students with theaim toeo<amine the feasibilityof this approa:h and refine the metho::lobgy, priortoentering K-12sdoolsthroughoot Maine. The UNE research team hoped toga in a better understandingas to complexity of the intervention ~,g.,grade-level comprehension), tefore administering itto K-12 students

S-.rl'l Bposi~().ySetl EJg-n~~~().n:l 91caP<IIJette

<Jti<f1'na0t','16)atlhe2015 STEM £l4IO.

Kindergarten-12th grade (K-12)educatbnaloutreach has grown at UN E over the years. Please visit www.une.ed uft esearc tvten/out reac hforexamples of UN E-drwen outreach eflbrts.As a UNE faculty memter, Professor Christian Teter, Pharm.D., has worked with UNE students from a variety of disciplines to offer K-12educatbnal outreach to Maine schools. There are two outcomes that Teter

K-12 OUTREACH PHASE 1: feasibility: Consisted of a cannabinoid eel ucational intervention (accompanied bya pre/p:lst assessment) given to small samples of UN Ecollege students.

59 I collegeof pharmacy I RISING TIDE

-

PHASE 1: The UNE research team spent thoughtful time and eftbrtdistillingan abundance of publicly availableand vetted materials from resp:cted sources, such as the National Institute on Drug Abuse (NIDA; w-vw.teens.d rugabuse,gov), into a relatively brief educational intervention. The team fee used on can nabi noid effects on the bra in, in add itioo to methcds of educating K-12 students. The intent was to include five levels of knowleel~ regard ingthe central nervous system (CNS) and substancesof use Qe.,cannabinoids).

Each level was meant to provide increasingly granular information:

K-12 OUTREACH PHASE 2:

•Refinement: cannabinoid

.

K-12 OUTREACH PHASE 3:

•Target Population: Final

eel ucational intervention (and

cannabinoid eel ucational

pre/p:,stassessment) was refined based u p:,n feedback obtained during Phase 1 and then given to add itbnal samples of UNE college students.

intervention (and pre/p:lst assessment) will te given to high school samples in the state of Maine.

Active Participation: Duringthe intervention development and refinement phases, the UNE research team exP3rimented with var bus a:tivities chosen sP3ciflcallyto increase student participation.

3- D BRAIN MODEL: Two-dimensbnal posters

were paired with three-dimensional brain mo::lels to enrich discussions. Potential effects of various substances (most not:ablycannabinoids)on the brain were discussed. Studentswere encoura~d to handle the brain model and sP3nd time latelingrelevant structures imp:,rt:antto su bst:ance use.

Pi0:I.Rdisatfains\f'l<4)Slt?,v.hicha:n1ainsapre-.n:lpos\~icMt.Jrm

<~ro,jaci-.t\'iSo:rnllU'l~acrosstie~e. htlis~e. ca'l~ro,js.re 1rMli"'fh:rn poSM\fl.iplic10 p-e-~cMt.Jn:n .nl ac$rt artr.b:s'·tirfis rYUWa1srnittr4'syswa SW'oe~torn·'Jhescm::eotMai)sla 1-r.JW'TMC.0.ffa hEtairt; Sd'dasic.nl tie ~CM lnsi-.tecn cn.g.ob.ise, trstp.bliShed 2011 (l),.41~1eat"'*.the.adsl.p.sdlewioxnvstJdEnts,,1he-sdE'n:e-Of-!MjlSla)

1. Brain: comp:mentof CNS (along with spinal cord)

2. Brain structures: cerebral cortex (among others) 3. Neurons:"brain cells" 4. Neurotransmitters: dopamine (amongothers) 5. Synapses: location in the brain where brain cells communicate

VETTED HANDOUTS: The UNE research team

thoroughly reviewed publiclyavailable materialsand used them to create a:tivityworksheet:s.

K-12 Outreach outcome assessment: The effica:y outcome chosen for the educational intervention was derived from multiple "risk of harm" items in the Monitoringthe Future Study (Johnston et al, 2016).

Students were as~d: "How much do }OU think

P3ople risk harmingthemselves physicallyand in other wa}IS when they smoke marijuana once or twice a week?" Resp:,nses included "no risk,""slight risk,""mo::lerate risk," and "great risk."

lhe UN Ereseadl te.Mn spent lh:11,thW 1iM .nd eff:lrt ds lillirt .n abUldaroe otplblidyavail~e .nd \-etted rnal:Eriais iMO a reia,...e1ybtief edl.£alional intEr\'EflllOn

RISIHCTIDE I collegeofpharmacy I 60

''

•

•''

•I I

I

2-drnenSional posws v.'1r'e ~red v,Uh 3-drnensional tf~n roodeis 1:0 ent1ch dsOJSSions

PHASE 2: As a resultof our intervention, partCipant:s

PHASE 3: Buildingon prior K-12outrea:hefforts,

demonstrated an increased P3rception of harm associated with cannabinoid use as well as increased

Christina ('Chrissy'' Fields (Pharmacy, '18) has obtained a list of Maine school health educators.

The UN E resea re h team plans to reach out to these schools, pending UNE IRB approval, 1br potential study recruitment.

competencyofcan nabinoid-sP3ciflc knowledge.

Based on student feed ta: kfrom sessbns, we revised our intervention and assessments to ultimatelyuse in the tar~t population of adolescents.

-

\m -

~ .re ZMl!a(Jtmna:y.'17)aid1t.n <Jtmn.o.,.'17).<il~ vMh ~rnfnber MEtfy.,i <JtmnGC\'.'1&).p-esEnli"' ~12 ~ at a poswsesSicn, tie:sesesSims .re.n tl'lpcrWltstep h p.rSl.i"'PMi"ad.icte plamG(\I resi~o.,.ndfti»W!lip CWortui1ies.

61 I collegeof pharmacy I RISING TIDE

t-wo.,s za...aia (Fh.rmac:y. '1 7).nd um 1t.n (Ftmnac:y. '1 7)asSisted v,Uh aealim .nd deli..UV oth edJcalional inter\'Efllion

How does THG affect behavior? It depends on whBl'B the CB receptors Bl'B In tbs brain.

Basal Ganglia

Amygdala

Hlpl)()Campus

Cerebelh.m Br.iln Structure Amygdala

Regulates emotions. fear, .anxiety

ea..lGanglla BratnStem

piitnning/$1:arting a movement

THC Effect on User

information between brain and spinal column motor coordlnatk>n. balance learning new information HyPOtllalamU> eating. sexual behavior Neocortox complex thlnklng, feeling. and moveme.nt Nucleus Accumbe.ns mottvatJon and reward Spinal Cord transmission ot lntormauon between body and brain Cerebeltum Hlppocampus

1

panl(/paranola $k>Wed reaction time andnausea effects Impaired coordination impaired memory increased appetite altered thlnklng,judgmen~ and sensation euphoria (fHllng good) attered pain sensitMty

vetted Mnlruts: lhe UN Erese<l'Ch tun tlct'rugl1y re',tev.Ed p.blidyMl<ible matr41<11s ,.n:l llSed ihErn 10 aeateaci',tty wotksheets. F'ct' ~~e, panidp;nts 'Mln? asbd ~ oonplete tie tablein b

'el.ft v.hile tlHOMng tie l~re

SOU'ce: A~ted ffOrn '1he Sdenceot M.rijll<V'la 1-klwTMC AHe;ts tie Br~n:¡sd'ldaslic.nd ihe Nalimal lnsli-.te on cr14 .ob1.1Se, 1irstplb1imed 2011

UN E student involvement: Pharm.D.candidates Marc us Zavala Ci 7)and Linh Tran Ci 7)were engaged in everystepof the research precess. Theyassisted

Portland Gampustoserve acomplementaryroe to the Btlde1brd Campus student neurosc ence group.

NHPC will help increase outrea:h efficiencyacross

with h}IP:ithesis and sP3c ilic aims development,

UNE campuses and help refine a scholarly K-i2

creation and deliveryofthe educational intervention, and outcomes assessment.

educational outrea:h approach. â&#x20AC;˘

In a::ldition to a:q uiringvaluable research skills, UN Estudents presented our findings at the American Sec ietyof Healthsystem Pharmacists QISHP) M id}ear Meeting. This pharmacy-centered conference isa ~element in the precess ofobtaining p:ist-gra::luate pharmacya::lvancementopp:,rtunities. future directions: Teterand U NE students from various programs have formed the Neuroscience in the Healthcare Professions Club (NH PC)on the

<lirm,.e<>blo?<N.Jni"','l&).duiSinaF"~ds(Fha-ffiaOt','1$,KEiy ~(JtlamG(\l,'1$.Vhlilney~(FhamG(\l,'1$..n:lff'stNMP< PresidEnt,Asl1ey<hace<Jtmn<l:>t','1&)

RISIHCTIDE I collegeofpharmacy I 62

I

I

It is no exaggera tiOn to say that the development of antibiotics revolutionized medicine. Unfortunately, antibiotics, once considered miracle drugs, are losing their effectiveness. The continuing emergence of antimicrobial resistance is a global health crisis and some fear that we are approaching a post-antibiotic era in which some infections are untreatable.

Shigell osi s, ca used by the bacterium Shigel/a fl exneri and related species, is one such infection. lnfact, in 2013, the Centers for Disease Control and Prevention designated antimicrobial-resistant Shige//a as a serious antibiotic resistance threat, one of only 12 microorganisms given that priority category.Although illnesses caused by Shigel/a are more common in developing natiOns across the world, in the United States each year Shigel/a causes approximately 500,000 diarrheal i Ilnesses, 5,500 hospitalizations and 40 deaths. The treatment of shigel Ios is is now complicated by the emergence of multi drug resistance to first-I ine therapies such as the anti microbial s ampicillin, chloramphenicol, tetracyclines and tri methoprim/s ulfamethoxazole.

Kayla Harris p:) P, '18) <ests the anti microoial susre pti bil ity of Sl>igella flemeri.

63 I college of pharmacy I RISING TIDE

George P. Allen, Pharm.D., associate professor and chair of the Department of Pharmacy Practice, has studied a variety of antimi crobia I-resistant bacteria in his laboratory in the College of Pharmacy, and his research has consistently involved Doctor of Pharmacy students. Allen has recently worked with Kayla Harris (COP, '18) to evaluate new antimicrobial therapies that may be options for the treatment of Shigel/a infections. Fluoroquinolone antimicrobials, such as ciprofloxacin and levofloxacin, have long been used to treat shigellosis, yet resistance to these agents, particularly ciprofloxacin, has recently increased.

Allen and Harris sought to determine whether fluoroquinolones other than ciprofloxacin might represent new potential therapies for shigellosis, and they also studied azithromycin and ceftriaxone, two agents that are currently recommended for shigel Iosis. They found that the continued use of either azithromycin or ceftriaxonewill lead to the development of resistance to these agents in S higella flexner i. On the other hand, they found that the fluoroquinolones levofloxacin and moxifloxacin only

assistant professor in the Department of Biology, with whom Harris investigated intra cellular mechanisms of survival for the infamous pathogen MRSA (methici II in-resistant Staphy/ ococcus aureus). Upon entering the UNE College of Pharmacy, Harris' curiosity regarding antimicrobial resistance was again piqued when she learned about Allen's research.

Explained Harris, ''.'1.ntimicrobial overuse in the medical community threatens the continued effectiveness of these medications. My concerns about increasing resistance and resulting treatment failures motivate me to continue Iearning more to understand the problem of antimicrobial resistance and investigate solutions for this threat to public health:'

..... - .......

-·'"" .........

•

A

'

George P. Allen, Pharm.D,aso::ciate professor of pharmacy pra;1ice,ard Kayla Harris ~OP, ·l8)attend the ASM Mtrol:econference in Beston, X:.16.

(but not ciprofloxacin) may prevent the emergence of further resistance in Shige/la fl exneri isolates with some degree of pre-existing fl uoroqui nolone resi sta nee. Si nee such Shigella flexner i organisms with baseline fluoroquinolone resistance are now circulating in many communities, this finding may have important implicatiOnsfor the treatment of this infectious disease.

Allen and Harris'workwas presented at the American Society for Microbiology (ASM) Microbe 2016 conference in Boston, Massachusetts, in June 2016.

ASM Microbe is an important international conference in which cutting-edge research concerning all aspects of microbiology and infectious diseases is presented.

All en is continuing his work WI th Harris and other Doctor of Pharmacy students to explore additional new therapeutic options for shigel losi s. •

Antimicrobial resistance has been an interest for Harris si nee her time at UN Eon the Biddeford Campus.

She was first exposed to this area of research as a student researcher with Kristin M. Burkholder, Ph.D.,

My concerns about increasing resistance and resulting treatment failures motivate me to continue learning more to understand the problem of antimicrobial resistance and investigate solutions for this threat to public health.

- Kayla Harris

Kay la Harris ~OP, '18) i:erforms workthat will QJantify the a:tivity of varOJs antimicrobialsagainst9>igella flemeli.

RISING TIDE

I college of pharmacy I 64

II the barriersthat stigma creates between patients and providers.As faculty members, we regularlyobsef\e students' discomfort toward treating patients with mental illness. We decide::I to take a closer look to observe whether psychiatric coursework has a mitigating effa:ton student stigma and whether interventions can improve student perceptionsof mental illness. These investigationswere successful due not only to student pan:icipation but also due to student involvement in the planning and e,,ecution of the design.

De'°' ShE'!'v.o:d, Pham\ D., BCPP

SURVEY OF STI.JDENTSTIGMABEFOREANDAFTER CORE DIDACTIC PSYCHIATRY COURSEWORK

Stigma 11:lWards mental illness hasexiste:lforcenturies Despite major improvements in psychiatric care over the last several da:ades, health care providers are lesscomfon:able providing services for patients With psychiatnc conditionsthan those with physical illnesses. This isespa:iallyconcerninggiventhat about one in five adults i nthe Unite::I States is living with a mental illness, and psychotropi: me::lications makl up nearly 20 percent of the most common me::lications dispensed in pharmacies. The issue raises the question ofwhethertheeducation health care providers ra:eive addresses student stigma towards mental ii lnessor

o•

...

Q2

OJ

~

"·

....

....

\!• ..

"'

12•.

"' 010

-

I !

.,,..

'

"""

65 I college of pharmacy I RI SI NG TIDE

.,...

1,,...

.;l\r"o

,...

'

11":.

1~··

.Jr:. !!-".

......

01 I QI

.,,...

-

:s•i.

I

u,.

~1'~111tfll¥J"« oot d1~

11i-.

!,·.

~

'"'

--

!&"•

·""

"'·

I

I

.,1%

""' -

.....

,,..

1)1•.

-

.n•.•

,_

Ju•.

11%

-

J.I~:.

,..,

u-..

...

In an effort to better understand pharmacy student stigma toward mental illness and how it compares to students in other health care professions, a study was developed to anonymously survey students in three UNE health professions programs (pharmacy, nursing and social work) using the Opening Minds Stigma Scale/or Healthcare Providers both before and after core didactic psychiatrycoursework. The impact ofcourseworkwas not statistically significant, as all programs yielde::I similar results with no remar1<able score change.

II",

I

I

health cnsis,e::lucated students aoout risk factors and warning ggnsfor mental health and addiction concerns, andexplaine::I wheretoturnfor help. Various methods to humanize mental illnesswere used, including bringing in a panel of speakers from the Nationa I Alliance on Mental Illness (NAMI) to discusstheir journeys living with a mental illness, having an autobiography book review le::I by awoman diagnosed with schizophrenia, reviewing the neurobiology thatcauses psychiatric illness, and holdingfocused topic reviews on pnmary pS)Chiatnc disorders. Resultsobservedwere remarkable with all 20 pharmacy studentsdemonstrating significant improvement in stigma toward mental illness. Thesefindings, which were obtaine::I by one UNE faculty member and t'WO pharmacy students completing independent study research, were presented at the 2016 COiiege of Psychiatric and Neurologic Pharmacists (CPNP) annual meeting and are currently being prepare::I for publication.

OMS-HC Average S.:Ores In Pharmacy Stuck>nts

• •

---

·-

••

---

• • • • RE:S1J Its demaisb'ate a o:rrp.,' isoo p-e/postclas:svak frcm 1he pl.rmGCy sbJdE'f'lt groop; n 2013 .nd 2014 • si.,~st~elediveoo..rstYJak hadap:isiti,,,~ irpad n red1.1:~st9Ntcw.rd rrmtalilhess.

SURVEY OF STUDENT STIGMA BEFORE AND AFTER A FOCUSED PSYCHIATRY ELECTIVE After learningthat psychiatry coursewor1< cbes rot appear to alter student stigma, the nert phaseofthe UNE studyevaluated if inter,entions in the classroom environment could improve stu::lent perceptions. A pharmacy ela:tive course was designed to address stigma and the propertreatmentof pS)Chiatric patients.

Thiselecti,e was the first pharmacycourse recorded in the United States to inclu::le Mental Health First Aid USAcertification. Thiseight-hourprogram provide::I training to assist some::,ne experiencing a mental

Health care stu::lents have been previously describe::I as prone to stigma and discomfort when interacting with patients with mental illness. Ourfindings are similar to previous stu::lies evaluatingother health care professionals and stu::lents aoout stigma. Engaging stu::lentsthrough focused ela:tivesor other activities beyond a didactic curriculum can da:rease social distance and stigma and ultimately improvetreatment of pe::,ple with psychiatncdisorders. •

Individual Student Scores - - - - - - - - - - - - - - - - - - - - i Ll Pre-Elective 50 - -45 44

., Post-Elective

43 42 42

-

_n. 39 38 38

.. 40 0

u

2

"' 30 (.) :c en 20

2

7

n

37 37 36 35

('

~

3 ~ 33 33 32 31

sJ

2828

1

::E 0

10 0

1 2 3 4

5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 Students

RISING TIDE

I collet"QOf pharmacy I 66

Theresa Foster, Pharm.D. '13and Alexandra Malinowski, Pharm.D. '14 were parttulartya:tive researcherswhile at the Uni\!ersityofNew England Colegeof Pharmacy, engaging in avaretyotresearch projects with memters of the faculty. Since their graduation, Fosterand Malinowski have pursued successful careers in the pharma:euttal industry,and toth attribute some of

their success to their research activities at the Colege of Pharmacy.

Foster is cu rrentlyempbyed as a pharmacovigilance sP3cialistat Biogen, Inc., based in Cam bridge, Massachusetts. Biogen sP3cializes in research and developmentof novel therapeutic a~nt:s for

neurologtal conditions such as multiple sclerosis, Alzheimer's disease, spinal muse ular atrophy, Parkinson's disease and am~trophic lateral sclerosis.

The company is also pu rsuingtreatment:s for rare genett disorders and is investigatingcutting,edge

technobgies such as ritonuceic a:id (RNA) medicines and genetheraPf. While a student at the College of Pharmacy, Foster primarilyworked with Olgun Guvench, M .D., Ph.D., associate professor and chair of the Dep:artmentof Pharmaceutical Sciences. Their work included

_._ .. ..

----

-QMPUTATIQNAL _..

E

Joumolof

---

HEMISTRY-....;...~-Z""

lheresa F'os w, Pham.D. '13 swids by h <M'les ~...er h Qnbtidge, Mas:sach.,setts,v,Uh ihe so~n sk..ÂŤine in tie b~Uld

computer-aided fragment-based drugdesign that may te used to discover novel targets for drugs, p:articularlytargets in\/Olved in protein-protein interactions. Some oftheirworkwas featured as a cover article in the Journol of Computotionol Chemistry in X:.12.

"PartC ipating in research projects duringmytime at the College of Pharmacyenabled me to develop skills outscle of the classroom that are fundamental to my roe as an industry pharmacist,''sacl Foster.

"Independent research projects cultivated my skills in bng-term project management, working in a group to reach a common research goal, and learningor exploring new skills such as computer co::ling, using biost:atistCs software and conductingextensive literature reviews.''

She added, 'Working on research artic es with Dr. Guvench allowed me toactivelycreate, analyze and convey my results toa sc entiflc community, all ofwhic h encompass my routine resp:,nsibilities as a pharmacovigilance scientist.''

6 7 I college of pharmacy

I

RISING TIDE

Bio::lefense and Emerging I nfectbus Diseases eighth Annual Retreat.

"Recognizingthe decline in research and development of novel antimicrobial agents by the pharma:eutical industrY, I tecame ~enlyinterested in research fee used on antimicrobial resistance,'' said Malinowski. "My v.orkwlth Dr.Allen largelyfo:used on pharma:okineti:/ pharmaco::l¥1am ic ana tyses of im p:,rta nt antimicrobialresistant bacteria. Through this v.ork, I fostered the skills to research relevant literature and identify knowledge gaps as well as wa'YS in which our work could contribute to the broa::ler infectious diseases and medical communities. I develop:d the abilityto criticallyanalyze data and com mun Cate fl ndings to the scientific community."

Malinowski continued, "In tandem with the required curriculum, indeP3ndent research demanded the capabilitytode11ebp, manage and eo<ecute l:oth shortand long-term projects with a clear objective in sight.

M~O'a M<lirowsSd, FtwmD. '14Sel:Sllp.n ELISAas:s~ toas:sess p-OtEin epressicninihel<ibor~yotDinel Sra:NJ,rese.rch

assodatepro*s:scrotbiCfl'ledcal sdenoes.

Malinowski is currentlyemplO)ed by Ultragen}'X Pharmaceutical, Inc., as a medical science liaison for the greater Boston, Massachusetts, area. She has also wor~d for Aexion Pharmaceuticals, Inc .and Synageva BioPharma Corp. Ultrageny,,c is a clinica~ sta~ biopharmaceutical company that is fee used on the devebpmentof novel therapies 1br rare and ultra-rare diseases, par tic ula rly serious, debilitating genetC diseases. The company's work is particularly imp:,rtant tecause of its fee us on diseases 1br which there are noapprooed therapies.

These skills translate well to mycu rrent roe as a medicalscience liaison supp:,rtingrare met:atolic tone diseases in the biopharmaceutical industry. In this role, I serve as a conduit for the broader medical communitybydevelcpingand maintainingprofessbnal relationships with current leaders in the field through the eo<change of knowledge concerningthe latest scientific informatbn available regardingrare diseases and related interventional therapies.'' •

At the College of Pharmacy, Malinowski v.or~d extensively in the latoratoryof George P.Allen, Pharm.D.,asscciate professorand chairofthe Departmentof Pharmacy Practice. Their research in\lOWed evaluations of novel antimC robial therapies for highly resistant bacteria, including Neisserio gonorrhoeoe and Klebsjello p,eum,njoe. Theirfmdings were presented ata num terof influential sc ientiflc conferences, includingthe I ntersc ence Conference on Antimicrobial Agents and Chemotherapy, the first International Conference on Polymy,,cins,and the New England Regional Center of Excelence in

M~O'a M<lirowsSd, FtwmD. '14\tjfl Lll<as: Lakoma,FtwmD. '13in oeorgeAHen'sl<ibcratoryattie<a1•otPh.rma(\'

RISIHCTIDE I collegeofpharmacy I 68

Novel Prognostic Marker for Aggressive Breast Cancer SRINIOI MOHAN,PH.0.,ASSISTANT PROFESSOR, DEPARTMENT OF PHARMACEUTICAL SCIENCES

and testcells in the latoratorysetting. Now,

Mohan'sworkhas resulted in his discovering "N OHA"(Nw-h}(lra<y-l-Arginine)asa sensitive and reliable ethnic-sp:ciflc indCa1Dr for ER- breastcancer early-prognosis, disease progression and treatmentoutcome. This means that NOHA has potential to be used as a way to detect aggressive ER- breast cancerearly, which means patients can start treatment early. Add ltionally, N OHA can be trac~d in these patents to ma~ sure their P3rsonalized therapy is helpingthem as exP3cted. The fl nding is so promisingthat the Universityof New England has filed for

To understand drug resistance, the latoratory of Assistant Professor Ron Hills, Ph.D., in the College of Pharmacy's Departmentof Pharma:eutical Sciences,develops mu It isca le mo::le Is to predict the molecular beh'J>liorofprotein transp:,rters involved in the absorption of drug mole: ues. In supp:,rt

of theirfull-time summer research in the lab, students Rachel Mc Devitt (COP, '18)and Cody Bia: k(COP, '18) won a U NE-wide fellowshipcom~tition and wor~d alongside p:,stdcctoral associate Jacob Fosso-Tande, Ph .0., in the Hills Lab.

U.S.and international patent protection to ensure that this new flndingiscommercialize::I so that Mohan 's workcan help as many breast cancer patients as p:issible.

Breastcancer is now known tote a varied disease, with different patients having different subtypss of breastcancer. Advances in treatment have included tlentifyingthe

subtype and indwiduallytaibringthe therapy on a patient-by-patent basis. looking at the differentgenes indifferent subtypes hasslown

Molecular Determinants of Drug Resistance

large differences in g:Jneexpression signatures tetween estrogen receptor-negative (ER-) and estrog'Jn receptor-p:isith'e (ER+) breast cancer tumors.Amongthem, ER- is a more

RONALD HILLS, PH .0., ASSISTANT PROFESSOR, DEPARTMENT OF PHARMACEUTICAL SCIENCES

FossljTande, who is a scholar from the Republic of Cameroon, stated, "Nothing isas exciting as applying the knowledge of

aggressive subt~, more diflicultto treat, has greater ethnic d isparityconcerns, worse prognosis and alma;t twice the risk cf roortality.

computational science toexpbre precesses ne:essaryfor life.''

Assistant professor Srinidi Mohan, Ph.D. in the Colle~ of Pharmacy's Department of Pharmaceutical Sciences has been working with Pharm.D. student researchers to grcm

R'Orn left 1:0 rtht, Rachel McDe-.ttt(<OP,'1$.nd Cody Blad< (<OP, 'l&)p.r1idpw!d in <Yi NSF' resudl tdlowship lln:IEr ties1,,per\tsicnotpostoo0:0r<11 as:sodate Jao:b F'oss~nn:le, FhD.,.n:I Rm Hills,Ph.D.â&#x20AC;˘in h<011~eOf Ph.rrnGOii

The d'Yflamics of biomolecules at the cell surface, includinghow molecules move a:ross the cell membrane,are crucial to our basic urderstandingof life precesses. Tte m01ement of molecules inscle and outside of cells is vital for taking in nutrients and eliminating wastes. It can also lead to the development

of drug-resistant bacteria and cancer.

69 I collegeo( pharrmcy I RISING TIDE

hsighl:s in~ rnaerul.r' mech.nsrns tro1Jgh oodeii~ 9'1.Jdent-gg-ierated rese.rch disc:o',(ftlj ~patb!ffl ot o:nsel\Ed <l"giline residJes on tie SU'flOe ottie M~A 1r.nspcner p-otEin,v.hk:h .r'e p-edcted 10 dth~ tie 1r.nspcrtot0'14S f'crnOEIIS.

The student-generated research resulted in the working hypothesis ofa pathway that allows for substrate transp:,rt in the P-gtycoprotein transporter resp:,nsible for acquired cellular multidrug resistance. The work was su pp:,rted by National Science Foundation grant MCB-1516826 RUI: "M ultiscale Models for ABCTransporter Mole: ular Dynamics,"with Hills servingas principal investigator.

Determining Whether Plastic Nanoparticles Change the Impact and Transport of Benzo[a] pyrene (B[a]P)

With regard 1o the unpredictable nature and rewards ofscientiflc research, Sutton said, "The students were a big helpand created a necessaryc ritical mass in the lab.

We search and search, then we sea re h again - but when it works, there is a great feelingof a:complishment!"

Presently, she is investigatingthe antifungal effect of poly.,lth i: ac a, which is a natural comp:,und found in this oil.

Just as patients with serious bacterial infections have to face the possibilltyof antibiotC-resistant ba:teria, others will *-:e the possibilityof fungal infectbns that ha'Je

STEVEN C. SUTTON, PH.0.,ASSOCIATE PROFESSOR, DEPARTMENT OF PHARMACEUTICAL SCIENCES

devebP3d resistance toexistingantifungal medicines. Amazingly, from Mizuno's studies,

Ben,o[a]pyrene (BaP) is a chemical than can result from the burningof cigarettes,gasoline and wcx:d. BaP is known 1o atta: h 1o DNA, which is the "cede of life"within all of our tx:dys cells. The attachment mayaffectthis

fungal infections. These compounds,de'Jeloped

by Mizu nds lal:ora1ory, may interfere with the abilityofa fungus to expel medicines. By bbckingthe ability of the fungus 1o eo<pel medicines,such poiy.,lth i: acid-based comp:,unds could ma~ existinganti-fungal therapes effect We again.

itap~ars that p:,lyalthic acid derivatives ha'Je the potential 1ofightotherwise resistant

co::le, resulting in diseases such as cancer.

Du ring the summer of 2016, twostudents worked to investigate BaPalongside

Associate Professor Steven "Steev" Sutton, Ph.D., felbw oftheAmerican Associatbn of Pharmaceutical Scientists.

Amelia F'<ffllml (<OP, 'l&)rneasu-es tie inb~,ny oth

oellrnmaÂĽ.

The work, performed in the College of Pharmacy's Departmentof Pharmaceutical Sciences,stud ed the effect of plastic

nanopartt es laden with BaP, as measured by their effect on intestinal barriercells in culture. In a::ldition to the deltate cell culture techn q ues, wh th require sP3cial care and feed ingofthe eel~. the research efforts empl~d specialized analytical instruments in the Department of Pharmaceutical Sciences

that can veryaccura1elydetectsmallquantites ofsP3ciflc chemicals.

Investigation of Antifungal Activities of Polyalthic Acid Derivatives CASSIA M 12 UNO, PH .0., ASSISTANT PROFESSOR, DEPARTMENT OF PHARMACEUTICAL SCIENCES The oil ofthe Brazilian copaibatree has bng teen used in tra:litional medicine for its healing proP3rties. The tree is found in the Amaa:in region ,and the oil can te tapP3d from the tree trunk in a manner similar to thewaymaples}'rupis tapped in New England.

s.,a 9taHml (<OP, 'l9)1ooks lhro'4fl a rniaoso:pe,ched<il'I tieq.i<11ityotoe11s inruve

Assistant Professor Ca5sia Mizuno, Ph.D., in the College of Pharmacy's D,partmentof Pharma:eutical Sc enc es, has develoP3d ongoing research effortsfo:usedon copaibaoil.

1he label on h botlle reads O tod);i 4?CCJ'l.)ijtro dcd>ei, Ftlrt1.1goese fCt' <opaifU'a dJcbi oil resin

Mizuno has engaged UN EPharm.D.students in her research ,as well as visitingsc holars on J-1 visas from Brazil, which is aft rstfor the College of Pharmacy. She is currentlyapplying for multi-~earfundingfrom the National Institutes of Health 1o further supportand expand this research.

RISINCTIOE I

co11egeo(pharmacy

I

70

.,..._...- 71 tc"otege-:f°O?ntal medicir.e I RISll'C TIDE

I

I

In 2014, Portland High &hool re-opened and dedicated the Amanda Rowe Heath Center, funded bya federal capital improvementgrant. The health center includes a dental clinic,albwingthe City of Portland 1o pre>1ide dentalcare 1ochildren from ages six months 1D 21 ~ears in Greater Portland, regardless of income or insurance.

The dental clinic is small, with on lyth ree chairs, but it is having a lar~ impact and growinglarger. Than ks to

a newly formed partnership, thirchearstudents in the Uni\lersityofNew England College of Dental Medicine (CDM) haue the opportu nity1o rotate through this

particularly rich forstudents as they get to intera:t with diverse patients from a variety of backgrounds.

Hillary Creed (CDM, '18)and Peter Pellegrini (CDM, '18), who ha\le justcompleted a rotation at the Portland High School dental clin i:, recently had a patient named Frankwhowas from Burundiand had only been in Maine fcr a 1:oJt fi\le months. Students Iike Creed and Pellegrini may also haue 1o nauigate the chalenge of provid ingservice to patents who

clinic to treat underserved P3diatric patients. U NE dental students s ~ nd fou rdays under the s UP3 rvision of JennyFultz Brunacini, M.S.W., D.D.S, providingexams, cleanings, fillings and oral health eel ucation. But they also earn about underserved p:,pu lations, navigating complicated langua~ barriers and the challenges of educatingpatient:s on how to test care for their teeth.

Students' exP3riences atoffsite clin ts and rotations directlysupport the mission of the College of Dental Medicine: to improve the health of northern New England and shape the future of dentistrythrough excelence in education, discoveryand service. Our ho~ isto instill in our students the call to serve others in need. The Portland High School Dental site is

HH.rv<reed(<DM,'1&).n:I Pew Nlqhi (<DM,'1&)1Jseahardsca1er .n:I g.ue 1:0reroovec:.1ru11JS ffOrna

~ent's teelh.

73 I collegeo( OOntal m::!dicire I RISII\C TIDE

privilege. These students are atan a~ when it is reallycrucial tosculpt the directbn of their oral health for many~ears to come. This is what we are tr}lingto doattheclint,and itfeels~dtobe involved in making a difference. The bigt,,stth ing I have learned so fur working at Portland High School is that even among all the cultural differences and age groups, it's imp:,rtant to keep a common goal in mind to promote oral health inscle and outside of thec lint."

This rotation is just the beginningofthe UNE dental students'off-site exP3riences.After two and a half lNs roodel disi,1a.,,"' tie 1:00lh d ~ p-ooess is llSed 1:0 derncnwate poWli<ild~iSSIJeS1:0~1S.n:lwai,,s1:0ttat~~dec:ayatlhediliC.

~ars learningdentistryand public health in their rigorous curriculum and treating patients in the Oral

require a interpreter, who have only been to a dental

Health Center, our students are rea::lyto hea::I out to

office once or twice in their lives, or who have

p:,sitively impa:tthe community. These partnerships

extreme emotional reactions to need ingdental care.

are teneflcial to all involved; our students are able to learn more atout public health service, clinics and

But these exP3riences -which unfotl under the watx:hfu I eye of Dr.Jenny- serve them well fortheir future careers

The patients at the Portland High School clinic truly value the om!

dental care, while patents receive high-level, compassbnate care.

The Collet,, of Dental Medicine is eoo: lted 1o be of servte to our local and state communities in supp:,rt

of our mission. â&#x20AC;˘

health care they are receiving, and I am thankful to have had such a motivating clinical experience.

- Hillary Creed

"The Portland High School rotatbn has given me the opp:,rtunity1o imp,ctthe Greater Portland community outside of the UNE Oral Health Center setting;' remarked Creed. "It has allowed metoprovidecareto avulnerable p:,pulation, whie appl}lingtheclintalskills that I have learned through myeducation at UNE. The patients at the Portland High School clinic truly value the oral health care tteyare receiving,and I amthankful to have ha::I such a motWatingclinical experience.''

Pellegrini echced his classmate,saying, "Working at Portland High School is a unique exP3rience for me compared 1oworklngatthe U NE Oral Health Center.

Beingable toworkwith ~unger patients whoare, in some cases, underserved or of foreign descent, where English is not theirfi rst language, has really been a

Hll.ry<reed(<DM,'1&).n:I ~ - Nlqili (<DM,'1$re-.t(Mla paient's CM'tbefcnplltllng en f'leir p-Ob:l;ive dOlhi~

RGINC TIDE I conegeo( dental m::i!dicine I 74

The Center for the EnrichmentofTea:hingand Learn ing(CETL)ser11es as a catal}'Stand su pp:,rtfor innovative, vibrant and effective teachingand learning at UNE. Tothatend, CETL last}'ear supp:,rted more than 160 events,tontacts im.ot.ling 386faculty, with CETl videos receiving more than 1600 vews.

Two CETl areas in which direct studentoutcomes are specifically measured are 1) the Scholarship of Teachingand learning (Soll) mini-grant program; and 2)the c urrentactive learningsp:aces research project, in which CETL is partneringwith global design man ufa:turer Herman Miller, Inc., toexamine the impact that a:tive learningclassrooms can have on instruction ,studentengagementand learning.

Eight Soll projects were funded for the 2015-16 }'ear.

Four of ttese projects a rd their outcomes a re desc rited in the followingfeatures. The fifth article describes the Researchingthe Environment in Active learning Spaces (REALS) project that is ongoing th is year. â&#x20AC;˘

77

I centers for excellence I RISll'IC TIDE

N~oM eperton ligher edJcalion ped.gogy, Urda N1scn. Fh.D. . s ~ on ou;cai tihld"' ata <E'TL aoss,o:,legeworksh:p.

Five }'ears ago, the U NE College of Osteopathic Medicine adopted an innovative fl rst-~ear integrated curriculum. The objective was to improved urable learningand its application to diagnostic reasoning skills byteachingthe traditional basic sciences in the contextof clinical cases. Because ofthe integrative and interactive nature of the course, remediation of a student who is not passing the course almostaM'ays requires re~atingthe year. This is acostlypros~ct toth in terms of time and money.

Several rep:,rt:s in the literature showed the risk of failure could be essened if students at riskoffailing

could te identified early in the course and concurrently enrolled ina remedial program.Topursuethisappl'C9:h, we needed away to identifystudents who might be at risk for failure as earlyas p:issible in the course.

One oftheteaching methods we adopted 1brthe course was the use offreq uentand mu ltipe assessments to assess student progress. These assessments are primaritycomp:ised of multiple-choice q uestbns and include weekly Format We Tests (Fl) containing X> questions each; Progress Tests (Pl) given every two to three weeks, which each have~ questions; and summatWe, 1»question Comprehensive Exams (CE) given at the end of each six-week block. In this study, we asked which of these assessments could te used to identifythe at-riskstudentand how early in the course

Todothiswedetermined at which p:,intduring Blcck1 we would be able to differentiate the top and tottom quarter ofthe class (asdetermined bystudents'final course grades)from analyzingstudent performance on the assessments. Using historical P3rformance data from the class of 2018, wefoundthatthe student performance on the FTs was quite variable and would not tea useful d iscriminatorfor identifyingat-riskstudents. Results for the three PTs and the CE during Bicek 1 were more promisingand are presented in Figure 1. These plotsshowa sep:aratbn between the top and bottom students that increased as the block progressed. In PT2, the !=es no longer ooerlapP3d, and they continued to separate in PT3 and CE.

fi1

'"•

I

"°"""THI' ' ' I • I I 11 I I , I II ,I , .

A,ul Course Gnde

____ • ,,....,_ • I

II

j """"'""'""'"'"'' . , ...11111111 11 11111. 1h11l1II .. :

F1n~ Course Grad•

Figu-e 2. ti ihese t'eq..en(\' pklts tiered dots rep-esent s11.dents wto 'Mlr'ebelowao.,tsononeiiher Progress ~t2 crihe<crnp-etmsi...e ~(1':9).n:lv.hat tleirflM oo.,rsegradewas¢,ottcrn)

this cou Id cccu r.

These data sug~st that we should be able to identify at-riskstudents by PT2 and certainly by CE1. Indeed, using these parameters and the P3rformance data 1br the class of X>19, we found thatthec utscore on the PT2 captured most of the students who failed the course butalsocaptured a numter of students who passed, while the c utscore on the CE captured all of

•

•

•

•

•

Figu-e1. 1hese ~ots show tiepErlOrrn.n::e Of tie 1:i:p ard bottom ~dents on tie Progress ~ .n:I <ortpl'UlenSi...e ~ in Block 1 1he bo,es ~resentsopercent Ofihe ~dents in each trOlP v.hile tie ~1s ateik side oo~n 25 percent Ofihe ~dents.

the studentswho failed and fewerstudents who passed (Figure 2). Therefore, in order to identify at-riskstudents as early as p:issible, we will use this cut score on PT2to initially identifythesestudents and referthem to the StudentAcademic Success Center. Studentswhodo not ma~ the cut score on the CE will be stronglyencouraged totakeadvanta~ of this program. Weare currentlyassessingthe outcomes of the implementation of this precess. •

R1S1NC TIDE I centers for excellence I 78

In an efforttoexpbre teaching metho::ls that can helpstudents make more connections among the

Withadditionalfundingin the form ofan Soll mini-grant last year, Stiegler-Bal1bu rwas able to

things they are learning,Jennifer Stieger-Balfour, Ph.D.,associate professor of ps}'(hology, recently

conduct a 1bllow-upstudytofurtherexplore tea:hing

launched two research projects totestwhether employingseveral new learninga:tivities would te

ex~rience forstudents by implementingthe flip~d

metho::ls that create a more dynamic learning classroom method. This method typi:ally has the

viable metho::ls forstrengtheningstudent interest in and retention of keyas~cts of course material.

In her Memoryand Cognition class, Stiegler-Balfour used s~ciallydesigned interactive we IF based ex~riments and comprehensive lab rep:,rts as a supplement to traditional lectures. Assessing the success of this strategy required comparingstudent ~rformances on essay exam questions in preparation fer which some students ha:I recewed ontyatraditional lecture whileothers had participated in the on line

ex~riment and,br prepared a sc entilic lab rep:,rt.

The results showed that the use of ex~riential learning ~nerated significantly tetter recall among students when compared tothosewhoonlyreceived a traditional lecture.

,, S~MS dsrus:s one Of tie hWd.<e 'Mlb-based e,periments in lheir ~oofy.nd <og,i1icn das:s.

79

I centers for excellence I RISll'IC TIDE

and shared with the students ahead of time so they

fa: ultycreate video lectures that are then uploaded

These results show that the flipped classroom method lends itself parti:u larlywell todifficult topi:s because

can view the lecture outside ofc lass. This allows for

students can watch the videoc lips mu ltipB times at

time in class tote devoted to a:tive learning in which the students applythe content and tecome involved in

home and have the opp:,rtu nity 1D ask questions in class while the professor is present as theycomplete

higher level thinking. Th us, totestwhether the flipped classroom metho::I would enhance problem-based learningskills, Stiegler-Balfour created multimedia

worksheetson putt in gt he concept into pra:tCe. Thesefmd ings were also reflected in the survey results, ind i:atingthatstudents benefited from having the proP3rsu~rtwhile completing the worksheets

videoclips forsomeofthe concepts covered in her Research Metho::ls course to compare the learning outcomes when usingthe video clips to more

in class and would welcome either aflipP3d classroom or a mix between flipP:(i and tra::1 itional

traditional teaching metho::ls.

classroom approa: hes for theirother classes.

Each exam was analyzed todetermine how effect We the flipped classroom method was for helpingstudents

Overall, the resu Its of l:oth studies indicate that encouragingstudent:s to tecome more self-directed

grasp toth relativelyeasyand mored iffic ultcou rse

learners byseekingout in1brmation and precessing it

concepts. I nterestinglY, it made no difference if the instructor used the tra:litional or the flipP3d classroom

at adeeP3r level ~elds tetter learningoutcomes compared to more traditional teachingapproa: hes. â&#x20AC;˘

metho::I for easer concepts; however, there was a sign iflcant improvement in earningoutcomes for more difflcultcourse concepts.

I

~

R1S1NC TIDE I centers for excellence I 80

The scholarshipof teachingand learning (Soll) in\lOhles inquiry into the effectWeness of new ~dagogical practices, with the ultimate goal teing improved student learning. The project descrited here was designed to integrate a new technobgy, the iPad Pro tablet, into the teachingtools of two anatomy courses offered last spring- I ntro::luctbn toAnatomyand Physiology I, taught byKaushik Dutta, M.S.,asscciate ecturer of Anatomy and Physblogy, Departmentof Biology, Colle~ ofArts and Sciences, and Biological Topics: Anatomy in ltaly,a new travel course, taught by Dutta and Mary Schwan~. Ph.D., adjunct pnofessorof Online Pathophysbbgy, College of Graduate and Professional Studies. The study, funded with a Soll mini-grant from UN E's Center for the Enrichment of Teachingand Learning, had two aims: to descrite how the iPad Pro could assist in the delivery of anatomCal contentand toexamine its impacton how students viewtheir learning.

The iPad Pro was used todelWer lecture material with split-screen capabilityvia projectbn toa large screen toenhance lab instruction to small groups, to provide a p:,rtable instruction device duringtravel in ltalY, and tocarryout "just in time" tea:h ing. Given the critical imp:,rtance of geed visual materials foraidingstudents in acquiringan u nderst:andingof the bcatbn and spatial relations of anatomical structures, the iPad

81 I centers for excellence I RISll'IC TIDE

Pro was extremely useful for enhancing interactive anatomy learning.

The most useful appforthe iPad Pro was a new version of 304Medical, which provided access to incredibly detailed and accurateanatomtal flgu res that could te dissected, isolated, rotated or viewed in su~rimp:,sed layers. Whie in Italy, the iPad Pro provaed a mobile tea: hing resource 1br identifying and explaining undertyingstructures while observingvarbus works

have priorexP3rience with tablet tee hnology in their courses, they resp:,nded veryfcl\lOrablytothe use of the iPad Pro. The surveydata also showed positi11e outcomes 1br students' P3rceptbns of their learning.

In I ntro::luctbn to Anatomy & Ph'YSiology I, a majority of students found that the iPad Pro, and specifically the 3D4Med i:al a pp for this tablet, helped them tetter understand the course material. In Anatomy in Italy, there were similar findings, espec iallywith reg,,rd to the use of the iPad Pro du ring the travel p:,rtion of the course.

I

In summary, this studysupp:,rts the incorporation

~

_______..

,

~ e s Ofh <4P, 3D4M?dical ,.:l'estov.n IYft .lighighli"' tie ce~ic-.Ein .nd m.,soJ~e1JrdEr1\I"' tie tight ..rn .nd dle:st Of Midlet.,.IO'S "Dao..d'1e1\).<Yid h toracoepigas1'ic~n .nl 1J1Jrk m.,soJ~reoth dassical SOJIP'l,l'e,·om"' sal\t''()ighO. ''D~d"was '-'e<M?d by UN£ ~dEnts h Bidogical 1t1i:-cs hm\00\' h ltaiyat tie ~1er1a DEll'accadEn'liain Flcnnce~''D;n::$"' $a¥'' was ct,~dbysil.dents at tie Gntia 9orthese in ~me.

of digital tee hnologysuch as the iPad Pro into the mo::lern tea: hing"toolkit"to improve anatomy

instruction. Stude ntcom me nts from course evaluations perhaps say it best: "I really liked how[Dutta]triedto use methc:dsother than just lectures to teach us the material. He used a few apps on his iPad Pro that helped:•

of Classical and Renaissance art and historicaldisplays

of anatomical specimens, including teautiful wax med els from the 18th cen tu ry.

Surve'YS were used to assess studentattitudes and pe re eptions a tout the use of d igita I tee hnology, includingthe iPad Pro,and its impact on their learning.

The results indicate that while most students d not

"I reallyenjO)ed havingthe technobgyavailable to help us tetter our understand ingofasubject in the field .... ltwasvery helpful to have the professor pull updifferent illustrations and 3Dviews of modules we were viewing in museums as questions came up." •

a

lhe i Pad Prow• 1Jsed h tle''fteld'dllingtle1"M cortpcnentot Elioklgical ltpiG: AAmllyin ~y. !Quslik C...1:ta, MS.,i~Silgates tie aco.,rclC>t'Of ~ modelS h tie ins ti11.JteotAAatll'l'\', Ui..e-Sityot SOklgna,wilh sU~ ~ Zffl'Chel'l'f'\' <,'1edcal Bidogy,'1&). ~er W~d (~ical Elidogy.'1$.nd Sl:maPM(~ical Elidogy.'1$.

R1S1NC TIDE I centers for excellence I 82

I .

.

I

Pharmaceutical comp:,unding is the art and science

were tested <or 1he level of concept and skill retentbn

of creating P3rsonalized pharmaceutical pro::I uct:s or medications, that are tailored to meet the unique requirements ofa patient The principles of pharmaceutical comp:,undingand its associated skills go be}'Ond dosages and formulations and often

qualitativetyth rough pre-session and p:,st-session

provide immense contributions to manyas~ct:sofdrug

research and development. A strongfoundation and thorough knowledge ofcomp:,u ndingwill always be beneficial for UNE College of Pharmacystudents for improvingtheircareeropp:,rtunities in pharma:eutical

and other health care sectors.

Recent studies have rep:,rted a grCN1ingtrend of diminished comp:,und in gs kills among graduating

surveys and also via analytical assessmentof their overall preparation.

Studentsurvey results showed a 91 P3rcent p:,sitive resp:,nse rate favoringreP3tition teyond instructor gu Dance tote an effective tool in providing improvement in their understandingof skill and comp:,undingconcepts. This result was additionally found tosigniflcantlycorrelate with an at least 33 P3rcent improvement in theoverall prescription qualityand active ingredient a:cu ra:y 'as determined

by analytical q uantitatbn). Thus, the methodologyof instructor-indeP3ndent reP3tition has shown initial teneflt towards improvingoverall student skills,

pharma:ist:s, which is a cause for concern. To address this concern and to improve student pharmacist compoundingskil~. Srinidi Mohan, Ph.D.,and Gurkishan Singh Chad ha, M.Sc., Ph.D., with funding supp:,rtfrom a Center for the EnrichmentofTea:hing

comp:,unding, to tetter suit the curricular delivery

and Learning mini-grant, evaluated the impactof

fordrugcompounding in the near future. â&#x20AC;˘

confldenceand trouble-shootingabilites. The current

methodobgywould need to be refined further, along with add itbnal elective courses on advanced drug

compoundingskill reinforcement through instructorindeP3ndent reP3tition mo::lules, wherein,students

in their ft rs t didactic }ear of their Doctor of Pharmacy

Co,npoo rded Cord iton

program were trained in comp:,undingskills.

In this study, <or the first three weeks, the students were asked to prepare prescriptions based on instructor~oordinated labs and were prov tied with additional instructbnal materials, namelya lab manual and instructor-develoP3d on line demonstration

videos that are available at www.une,edu/phs104.

Fort he next three weeks, in addition toan instructorguided com p:,unding lab session ,students were instructed to reP3ata prescriptbn without any instructor gu tlance.Atthe end of each three-week session,studentswere gWen an opp:,rtunityto reP3at or prepare a formulatbn without reP3titbn. They

83 I centers for 00:e11ence I RISll'IC TIDE

a skm a 1trut4eshooli'lg a OvEr<ill cordaderoe â&#x20AC;˘ rep-eSUli:S sig,iflc.n::e be\'M?t"Sl gro.,ps, P,QOl. n =e6 [pos~h:lc.rl<ilySis: Tl.m?y.rld Bontu'cnli] lhereialicnmip~sUentS1JI\Eysons.restov.n.v,Uh.n:I ....uroot corrpWldngreinfet'anlent ~ sklll ,.bilityto wlbiemoot .n:I o.Er<ill CDl'dldEnce.

set-u pof these renovated rooms.

Craig Owens, ac linical assistant professor of social work, is among the fucultyteac hing in Blewett 108, and he calls it his ' <:I ream classroom."

Caryn H usman,assistantc lin Cal professor and coordinator for Health, Wellness and Occu patbnal Studies, is one ofeightfucultyteac hing in Marcil 303.

She described the classroom as being'equipped with fexible and variable seatingarrangements that allow <or optimal fluidityand fle0<ibillty. Students can select seating to match their learningstytes -theycan choose a standard table,a high-toptable, bench seatingora comfortabe chair with aside table. The room design is chan~able; therefore, the environment facilitates use ofvaried learningexP3riences. Media sc reensand white toardscoverthewalls to facilitate group earning a:tivitesand use of the newesteducational technology.

The rooms are also designed with comfortand aesthetics in mind, makingthec lass room a pla:e where learn ingis a pleasure.''

The U NE Center <or the En ric hmentofTeac hing and l.earni ng (CETL), alongwith UN E Fae ilities and ln<ormation Tee hnology Servi:es (ITS),are collatoratingwith Herman Miller, I nc.,a mapr

American manufa:turer of office furniture and equipment, whth conducts an ongoingprojectcalled the Learning Spa:es Research Program.

By participating in the program, U NE will test ways to design space that supports the latest pedagogical metho::ls and learningst~es.

In January '.X:l16, a visioningworkshopwas hetl with

fac ultyfrom the Colle~ of Arts and Sciences and the Westbrook Coll,ge of Health Professions whoa re interested in tea:h in gin a:tWe learningspa:es. They were joined bytwostudent representatives, along

with CETL, ITS,and Fae ilities staff, to work with Herman Miler, I re., to redesign two mid-size classrooms tapacityof 32)thatwould be renovated over the summer: Blewett 108 and Marcil 303.

In August, fa:u ltymembers assigned to teach in the two classrooms partt ipated in a one-daytrainingon actWe earningtechniques, with a focus on thesP3ciflc

Anecdotallythus far, Hus man indicates that students rep:,rtenjoyingthe different seatingoptbns and that they are more likely to participate in discussions.

Students also note that theyenter the class room ready tote active participants.Hus man also rep:,rt:s that the room affords opp:,rtunities toemploya:tive learningstrategies with ease. She stated, "More broadly, Health, Wellness and Occupational Studies professors are considering how the environment impa:ts the ccc upation of learning. Usingan occupational science lens, they p:,stu late that interaction with the objects in the room affords learningthat is creative, student-centered and individualized. Theyfu rthercontend that this learning environment impacts the culture of tea: hingand learning in a mannerthat promotes the value ofdeep thought, problem solving and lifebng learn in gas exP3rienced through a:tWe learning.''

Cu rrentty, research is beingconducted focused on students' P3rceived evel ofstudentengagement in traditional classrooms versus these new learning spa:es. Add itbnally, observatbns will cccu r using a proto:ol centeringon buitlingattributes and a:tWites as well as structured interviews with*-: ultyand students. Resultswill bed isseminated in thespring. â&#x20AC;˘

RISING TIDE I centers <orexce11ence I 84

have grown in stepwith the growth of the cores, developingand ~rfecting new techniques in the fletl, which, in turn,stimulates the success of the cores.

NEW EXTERNAL FUNDING The Center has wor !al tireless ly1o provides uJ:IX)rt and gu Dance to several junior scientists as theyest:ablish inde~ndent,extramurallyfunded research programs.

Peb"4' c,,admna, S.S. ¡13, lab rn~roth Mn:,logy .n:l l~ning

<ere ,hasber4lins1ru"l'lental 10itss1.1X1eSS. The Center of Excellence in the Neuroscences (CEN) is an umbrellagroupthat brings to~ther neuroscientists from multiple colle~s to a::ld ress neurosc enc& related initiatives at UNEand in the greater canmunity.

The CEN is heavily in'-'Olved in undergraduateeducatbn and has a11erya:ti11e K-12 Outreach program.Another major arm of the CEN is neuroscience research. Within this arm lies the Center for Biomedical Research Ei<x:ellence (COBRE)forthe Study of Pain and Sensory Functbn. The Center is made-up of COBRE-funded neuroscience latoratories at UNE that workto~ther 1oadd 1oa better understand ingofthe neurobiology ofacute and chronC pain. The Center recetved a COBRE grant from the National Institute of General Medical Sciences in Septemter 2012 and, since then, this grant has provided support 1br a collatorative group of neuroscience researchers at U NE.

Recently, those efforts proved successful as two COBRE project lea::lers received external funding.

Geoffrey Ganter, Ph.D., professor of biology, College of Arts and Sciences, received an R15AREAgrant in early 2016, and proj,ct leader Ling Cao, M.D., Ph.D., associate professor of biomed Cal sciences, Colle~ of Osteopathic Medicine, was awarded an R01 in Ju ty.

These new awards have made it p:,ssible to su pp:,rt a::lditional neuroscience researchers, including Michael Burman, Ph.D.,associate professor of psychology, College of Arts and Sciences,and a new ta:u lty memter, Ben Harrison, Ph.D.,assistant professor in the Department of Biomedical Sciences, College of Osteopathic Medicine. eoth Burman and Harrison are taking on new roles as COBRE project eaders.

Furtherroore,a numtercfother research programs have received awards for projects in which collatoratbns tetween neuroscience investigators have led to add ltbnal funding1br COB RE project leaders. Tamara King, Ph.D., associate professor in the Department of Bbmedical Scences, Cole~ of Osteopathic Medicine, and Lei Lei, Ph.D.,associate professor of biology, College of Arts and Sciences,are Cljinvestigators on R01 grants recei11ed by caoand Ian Meng, Ph.D.

NEW RESEARCH CORES One of the ft rsttangible outtomes of the COB RE grant was thecreationoftworesearch cores:a Behavior Core and a H istobgyand Imaging Core.

These research cores were designed to provide ex~rt a::lvice, training and servCes to COBRE project ea::lers.

More recently, the cores have extended their services to irwestigators toth within and outside UNE, including collatoratingon projects with external contributors.

The cores have provided trainings tofaculty,st:aff and students. In the pasttwo~ears alone, the cores have performed more than 240 individual trainings inn umerous tee hniques. Core managers and staff

85 I centers for excellence I RISll'IC TIDE

S6M

115M $4M $3M $2 M

$1 M

2014-15

2015-16

GOhr a NIM Bcr's~resentn(Mlg,-.ntda1.rsre:iei...ed~neu-osder.::ei1MS1ig~rs o.erf'le pasttou- ye..,'S. 'Oita'' is rep-esentall...e Of e:dem<il s1,,pport lmtisnot Nll+nitated.

Katherine Hanlon, Ph.D., assistant professor, Colle~ of Osteopathic Medicine, used data from the project for a prestigious Rita Alien Fou ndatbn grants ubm ission.

$16M $14M $12M $10M SOM S6M S4M $2M

so

2012-13

2CQ.3-14 201~15 1iOtlE'S' a NIM

2015-16

B.rs rep-esent tie total gr<flt OOH.rs req.iestEd bynei.irosdenO? in..,,e:s1lg~s~rflepasHoU'yEWS. 'Ok'isrep-esentali~Of ~IM s1,,pport tlatis rot N11+re1ated

Alto~ther, since receivingthe COBRE award, six external grants have been awarded with notices totaling more than $2.7 million.

NEW PILOT PROJECTS.NEW COLLABORATIONS Collatoratbns among COBRE researchers have eo<tended in1othe COBRE pilot projects. A pibt project

by Katherine Rudolph, PT, Ph.D.,associate professor of ph}'Sical therapy, Westbrook COiiege of Health Professbns, was converted into an R15AREAgrant, awarded in April X:.16, in which she is collatorating with Tamara King. Kingalsoworked with Glenn Ste.enson, Ph.D., professor of biology, College of Arts and Sciences, on a pilot project investigating osteoarthritis for whCh Stevenson was awarded a three-}'ear R15 AREA grant. In another pilot project,

Derek Molliver, Ph.D,asso:iate professor of bbmedical sciences, Colege of Osteopathic Medicine, offered gu Dance on Han Ion's project Finally, recent pibt recipients from the Colle~ of Osteopathic Medicine, KerryTuc~r. Ph.D.,asscciate professor of biomedical sciences,ard Meghan May, Ph.D.,asscciate ~ofessorof biomedical sciences, have teen workingcloselywith COBRE men1ors and project leaders. Both Tuc~rand May will haue their pilot projects extended forth is }ear. Tot,,ther, these faculty members haue helped create a dynam C and diverse center.

The impa:t of the COBREgranton our institution has teen trulytrans1brmatWe. One final collatoration, and the most critical, has teen institutbnal investment in the center's program bya num terof UNE departments and collet,,s. The center has been 1brtunate for such institutional investments in the recruitmentof new fa: ulty, increased research infrastructure through latoratory renovatbns, a:quisitbn of new instrumentation and supp:,rtfor investigators through research cores. Furthermore, the COBREand the CEN haue v.or~d with other colle~s and departments to bring more than 75 invited spea~rs from across the world to UN E over the past four ~ars. With continued investment prouided th rough Phase II fundingand institutional supp:,rt, we will build on ourearlysuccess and further establish thecenteras a eader in pain research. â&#x20AC;˘

t-m.,

Stehao..ct'Ccre t..., SU"gqlist,8.S..RlA,t,llSes tie tuoO'cp sp~to~me\?rto qlallifyrbmldeicadd <RNO.)coroenfalions in

as.nple.

<OBREi1MS1igat1rs.~dEn1S.ndNffattEl'dihefltlt1heastR~mGI IDeA<onteninceinSiepWl'ber2015.

R1S1NC TIDE I centers for excellence I 86

Since the o~n ingof the Center of Excellence in the Neurosciences (CEN), the numter of master's degree seekingstudents, Ph.D. candidates and p:,st-doc1oral fellows working in UNE's neuroscience labs has

To date, five students have receWed their master's degrees. UC Davis professor Earl cars tens testified to the success of the training received by these students when he praised Ph .D.studentand center alum Taylor

increased exp:,nentially. U NE neuroscience has come a longwaysince the da}IS when there were mostly undergra:I uates or medical students in the labs. The larger num ters of projects and lab empl~ees have allowed 1br increased collatoratbn with ex~rt:swithin and outscle ofone's own subjectarea,greatera:cess to shared resources, greater networkingopp:,rtunities, and tetter problem-soh/ingopp:,rtun ites, as a larger and wider ran~ of ~rs~ctives are availabe to assist with technical problems.

Follanstee in a recent letter to CEN Director Ian Meng, Ph.D., which said, "Taylor has benefited from outst:andingtrainingand scientific process,as well as technical skills that were offered to him as an

The CEN and Center 1br Biomed Cal Research Excellence (COBRE)for the Studyof Pain and Sensory Function have provided supp:,rt 1br nine students enrolled in the Master of Science in Bbmedical Sciences program who have worked in neuroscience labs.

Even though it was only a few short years ago when undergraduates sue has Jill Hoffman, B.S. 03, Ph.D., cou ti ex~ct her research intera:tions to be with fa: ultyorotherstudents, it seems Ii~ a lifetime awaywhen compared to the varetyof educatbnal attainment levels represented by people workingin the labs 1oday. (See the CEN section 1br more information on Jill and her research path.)

87 I centers for excellence I RISll'IC TIDE

Pos~.11 R'dlow~e Sle<IJdlernh,FhD.,woksinhGMIWL.ib<IKlrtSidernâ&#x20AC;˘trrs~OYlt<runney er.n,BS. '16,(MS. aornedic:all SdEn:ES,'l&)dasSity"' tyl~

undergra:l uate and master~ student at UNE:' (See the CAS section for more information on Taybrand

his research.)

16

COB Rf Cr.id sb.Jdent / post do:s

14 12

10

• 6 4

2 O

L _ _ _ _....1,,,. ..1_ _......_.c__ ....1,_.L2012

,on 2014 • FhD. a MS. a Post Doc

2015

B.rs rep-esent tie nUllber Ofgrad.late ~dents .vld postloctor<II fellows in UN E'S p~n research l<ibor~ies siroe 2012.

Mchaiel AAOlr'Scn, s.s. '13, MS '15 imtks en his tlesiS proje«, ilM!:Sigalingtieroleotat'.nsaipionfiett,SOd1,in~~ngn~

May 2016 mar~d the graduation of the first UNE student 1o be enrolled in the Graduate School of Biomedical Science and Engineering (GSBSE). The GSBSE program is run bythe Uni\!ersityof Maine, whi:h grants the Ph.D.degrees but is made up of five other research institutes across the state of Maine, including the Uni\!ersityof New England Colle~ of Osteopath i: Medicine, the Ja: !Gon Latoratory, Maine Medical Center Research Institute, the Mount Desert Island

. . . .Eralicn <Yid MYl'(pahicj»n talOMnginjlfy.

BiologCal Latoratoryand the Universityof Southern Maine's Department of Applied Medical Sciences. To date,se\!en GSBSE students haue also rotated though neuroscience labs at UNE.

Virginia Mclane, Ph.D., completed her thesis dissertation work in a labora1oryof Ling cao, Ph.D., associate professor in the Department of Biomed Cal Sciences, Colege of Osteopathic Medicine. (See the CEN section 1br more information on Mc Lane and herresearc h.)

The COBRE grant has been able 1o prouide support 1ofi\!e GSBSE students ouerthe pastfou ryears. In a::ldition,as part of a requirement of the program ,a number ofother GSBSEstudents haue rotated through neurosc ence tatoratories at UNE. A more recentaddition to the CEN community has teen the presence of p:istdcctoral fellows in our neuroscience labs. At the teginningofthe COB RE in 2012, there were no fellows working in UN E's neurosc enc es labs. To::lay, there are six, three of whom ha\!e received COB RE support. These felbws

Po~ctir<ii F'ellcm seti Dat..s. Ph.D. ,mCMIS os SSE ~ent<<f'aSIJlli'lal, 8.A •MS. ,anewtechniq.Jeon

are a fresh a::ldition to the comm unity, bringingwith them different skill sets, new pers~ctives and varied protlem-solvingskllls. It is eo<pectedthat thiscommunity will continue togrowalongscle the neuroscience

tieaysostat

research at UN E. •

R1S1NC TIDE I centers for excellence I 88

tecome involved with the work in the Darnall Lab.At the time, Darnell was collatoratingwith agroupof researchers centered at eoston Chi ti re n's Hospital, investigatingthe causes of sudden infclntdeath s}'lld rome (SIDS). In 2005, Hoffman became a research studycoordinatorat eoston Children's Hospital working with Hannah Kinney, M.D. With Hoffman in eoston, Mokler naturally came to meet her new colleagues. After a short time, Mokler began tocollal:orate with her SI OS group in Boston, which led toa key publication in The Journo/ of the Americon Medicol Assock?tion (J/JMA) (Duncan eta I., 2010). Mokler, Hoffman, and Jhod;, Duncan, Ph.D., a p:,stxla:toral fellow in Kin neys lab, analyzed levels of serotonin in p:ist-mortem tissue from children who Jil 1-bflhm. Fh D.

Jill Hoffman, B.S. 03, Ph.D. '12, began her research career as an undergraduate student in the latoratory of Dava Mokler, Ph.D. in the Colle~ of Osteopathic Medicine in X:01.Jillwasstud}lingmedCal biobgy,and several of herfriends were doingu ndergraduate research. Jill bo~d u pthe pharmacology professors and reached out to Mokler. She recalled,"When I met Dr. Mokler I knew it would beagreatfit.l remember sitting with him in his office in Stella Maris the day that we met,and he opened upa hu~ filecabinetand pulled out a few glossy reprints ofarticesandgave them 1D me to read. I remember being so eoo: lted to read through them. I also remember asherof teo<tlxx,ks he had,and tor rowing many, includingone in particular called The Bfochemicol Bo5Js of Ne1.Kophormocology. It included a chapteratoutserotonin that I read over and over.

When I graduated, he gave me my own co pt with a note he ha::I written on the inside cover. ltsaid: 'Your future is bright. Wear sunglasses!' That book means so much to me."

Mokler inultedJillto i:resentherworkin his labatthe ExP3rimental Bblcgymeetingin San Dego, where she met Robert Darnell,M.D., firom Dartmou1h Medical School. Based on her exP3rience with Mokler,she was offered a job as a technician in Darnall's lab. Once there, she investigated the roe of serotonin in thermogenesis in piglets, which led to a::ld itbnal p:aP3rs and presentatbns. Since Darnall was working with serotonin as well, it was natural for Mokler to

89 I centers for excellence I RISll'IC TIDE

had died of SI OS. This line of study can be partially credited to the networklngand collal:oratbn that occurs in research fields.

Hoffman made a transitbn in 2007 when she appled and was a:cepted to the neuroscience program at the UniversityofVermont. She continued herworkwith serotonin byjoiningthe labofGary Mawe, Ph.D. Mawe is an internationally recognized exP3rt in serotonin's role in the gastrointestinal system ,and Hoffman profited greatly from her time with him. She graduated with her Ph.D. in 2012, and her research with Mawe ed toanotherseven publicatbns. Thus, by the time she had earned herda:torate, Hoffman had 12 publicatioos.

Hoffman is now a postdoctoral fellow at the Center for Inflammatory eowe1 Diseases at the Universityof Galifornia, Los An~les in the lal:oratoryof Charalal:os Pothoulakis, M.D., where she continued stud}'ing serotonin in the gut. From there,she became fascinated with the ner\lOus system of the gut and how it reacts to stress and inflammation. From her research with Mokler,she has a fantastic publishing record (which potential emplO)ers will approve ol), she has earned her Ph.D. with excellentlyvaried work exP3riences,and she hascultWatedan impressive netwcrkofcolleagues. HerearlyexP3riences in neurosc ence research have truly set her u pfora successfu Icareer! â&#x20AC;˘

Uli..u-Sityot ~ne<onrnen::iement CErlrnef\' en M~14,2016.

OSBSEgrad~ lineup at lhe ~ 2016 Uli\'Er'Sity ot Maine <crnrtMOtYl\Eflt<E'ftm:11\'<Jeft 10 ligh\) Mqwl B~in, K\t? ~dYSl'lin,9eaJ Roswna.Deeplli M.itlW'iStn<Yi,S<f'kl F'eta'son. \Atlilia M;L.ft .n:I ~.rtin l<i~ Fh~<4hed t,.. w::>t' u~. MMCRI.

In May 2016, Ling Ca:,, M.D., Ph.D.,associate professor in the Departmentof Biomedical Sc enc es, College of Osteopathic Medicine (COM)graduated herfirstPh.D. student, Virginia Mclane. Mclane was a PhD.student enrolled in the Graduate School of BiomedCal Scence and Engineering(GSBSE) program from September

Opiates on Central Ner\/Ous System Immune Defense in Murine AIDS," under the mentorshipof Cao, in Cao's neuroim munology research latoratory in the UN E COiiege of Osteopathic Medicine. She published her first manuscript in the Journal of NeuroimmlKlology in early X:.14. She has also presented herworkat

2011 to May 2016. The GSBSE program is unique in that it in\/Olves six cooP3ratingacademic and research institutions within Maine: the University

var bus national, regional and local conferences. In addition, Mclane has presented herworkatevery annual meeting ofthe Sccietyfor Neuroscence (SFN)

of Maine, the Jackson latoratory, Maine Medical Center Research Institute (MMCRI), the Mount Desert Island Biological Lal:oratory (MDIBL), the Universityof Southern Maine (USM) and University of New England (UNE), with the Universityof Maine servingas the degre&granting institution.

since X:.13. Recently, she was selected to give an oral presentation at the 2016 SFN meeting in San Diego, Gali1brnia,discussingsome of her thesis research in a presentation titled '1"yP31 Interferon Signaling in Morphine-potentiated LP-BM5 M urine AIDS." In recognition ofheroutst:andingacademic P3r1brmance, Mclane was awarded tie MichaelJ .EckardtDissertatbn Fellowshipfor the 2015-2016academic year, which prouided her with a stipend of $20 ,OC()ouer 12 months.

\Arghia Mct..ne re:iei...es her Ph.D. hood t'Orn OS9S EDireO:Or Da,.,,j ~Wfldt.FhD.4efO.<Yid u~nePro..osUefhy ÂŁ Med<U'4ight>atlhe

Mclane was the first Ph.D.student in the GSBSE program who selected neuroscience as her research fee us area. She completed her thesis project, "Effects ct

Following graduation, Mclane continued herscientiflc career by joiningthe latoratoryof Ku rt Hauser in the Departmentof Pharma:obgyand TaxCobgy, Virginia Commonwealth Un Wersity, as a p:istdoctoral fellow.

Hauser is a world-renowned researcher investigating the intera:tbns between drug abuse and central nervous S'YStem plasticity.

Mc lane's accomplishments at UNE are another testament to the rap growth of UN E~ research

a

capa:itY, particularlyin neuroscience research. Over the past several years, interest among GSBSEstudents in working with investigators at U NE has increased significantly. There are currentlyfour GSBSE students completingtheir thesis research at UN E. â&#x20AC;˘

R1S1NC TIDE I centers for excellence I 90

The Center for Excellence in the Neurosciences (CEN) at UNE was well represented at the second annual Maine Science FestWal in March 2016. Held in Bangor, Maine, thetwo-dayfestival was visited by more than 10,<XX! people. Well o,er 1,000 peope visited the CEN eo<hibition,and 1he CEN was gratefulforthe support of all the \/Olunteers, including 19 undergraduate and graduate students from the College of Pharmacy, the COiiege of Osteopathic Medi:ineand 1he COiiege of Arts and Scences. Fa:ultyfrom the CEN in attendance included Michael Burman, Ph.D.,asscc iate professor of psychology, College of Arts and Sciences, and CEN Outreach Program coordinator; KerryTuc ~r. Ph.D., associate professor in the Department of Biomedical Sciences, Colle~ of Osteopath C Med Cine; Ian Meng, Ph.D, directorofthe Center of Biomedical Research Ei<x:ellence (COBRE)forthe Study of Pain and Sensory Functbn; Edward Bilsky, Ph.D., vice presaentof Research and Scholarship; and cassandra Simmons, B.S. '15, outreach staff coordinator.

The CEN designed the mu Itâ&#x20AC;˘ part eo<h i bit to beenpya be and educatbnalforalla~s. First, rredical students and fa: ulty intro:! uced visitors to neuroanatomy. CEN \IOI un1eers ha:I created an ed ucatiooa Iexhibit,featuring more than X> different human brain s~cimens in order to highlight the function of different brain regbnsand common brain disorders. The second part of the exhibit was the family-friendly"Brain Exploration Station ,''wh Ch used a variety of interactive exhibits toenga~ the public in hands-on

91 I centers for excellence I RISll'IC TIDE

learningatoutthe brain. This included a mCroscopy table with vewable slices of the brain and acomp:a~ tive anatomystatbn with CCNI, sheep and rat brains.

Volunteers demonstrated tovisi1Drs the imp:,rtance of helmetsafetythrough proper helmet fitting, ma~~u r-CN1n helmetactivites, and eggdropand melon dropdemonstrations (the eggs and the melons standing in 1brthe human head).

Visitors also found interactive activities that included a MindFexgameanda musclestimulationgame in which people could attach electrc:des to their bodies and control the muse le movementofanother individual's arm. Notto te excluded, the youngest neurosc ence enthusiastswere greeted with s~cial coloring books and directbns for making pi~ cleaner neurons. â&#x20AC;˘

Wime,soth~oM l:r~nbeeo:rnpetein tie US.A.naliCM cortpeliiicnSrutlem M~ne"SY-'nnEr(~ÂŤe~- backrowCl!flW,boes~mk10lh ~aoeo.u'<ill.

In Decemter X:.15, the Center of Bo:ellence in the Neurosciences (CEN) hosted the second annual Southern Maine Regional Brain Bee. High school students from Thornton Academy, Kennebunk High School and Biddeford High School attended. In addition to the hou r-longquiz-style com~tition, the CEN offered an afternoon ofactivities toe)((ite students to learn a tout the brain. These a:tivities included an ooerviewof human neuroanatomy guided by UNE medical students, using donated human brain tissue, sheep brain dissections guided

by UNE undergraduate students,and microscopy lessons assisted by CEN volunteers.

Michael Burman, Ph.D.,asscciate professor in the D,partmentof Ps}Chologyand facultycoordina1or of UN E's Center 1br E)((ellence in the Neu rosciences

K-12 Outrea:h Program, coordinated the event along with Emily'Mlrner, B.S. '15. Dr.Burman sac of the event's success, "Our goal is to helpsupp:,rt STEM education in our neightoringschool districts. I think ~u can reallysee the effectiveness of the program in the enthusiasm these students are showingforthe Brain Bee. The amount of time outside the class room thatthey\/e put into preparation is incredible.''

The Southern Maine Bee was held simultaneoustyand in collatoration with the Northern Maine Brain Bee at the Universityof Maine in Presque lsle,and the Western Maine Brain Bee at the Universityof Maine in Machias. The Brain Bees provide an opp:,rtun ity lbr students 1odemonstrate their know led~ atout the brain and ner\/Ous system whie motivatingthem to pursuecareers in neuroscience. There are currently atout 1~ local Brain Bee coordinators in 3::>countries worldwidewho conductcompetitions annually.

Winners of regbnal Brain Bees travel to the Natbnal Brain Bee tocom~te for the U.S.c ham pionshiptitle and an invitation to travel to the International Brain Bee com~tition. The winner of the Southern Maine Brain Bee, K}'le Ryan from Kennebunk High School, went on to place tenth in the nation and has started a successfu lonline neurosc ence purnal for high school students.

The third annual Southern Maine Brain Bee was hosted on Dec. 6, 2016,and was coordinated by Haley Lawbr (Physical Therapy, '19). â&#x20AC;˘

R1S1NC TIDE I centers for excellence I 92

F'ao.iltytadli~ M.ry Pl.be. MS. Ed ,.n:I sM1ey<otm Kmad, Fh D.,obs~ as ~~ts torn tie intErp-oeSioM te?n '9'ight PA.ire'''I.Q'ki:Ogelta' 1:0 p-epn fct' adienti~ew.

For three years, the UN EI nterprofessional Education Collal:oratwe QPEC) has offered a highly-interactive extra-curricu tar program called the I nterprofessional

cross-professional learningexP3riences. Seats in IPTI are limited to six selected students from each of eight different health professbns programs across

Team Immersion (IPTl). IPTI is adevelopmental, longitudinal and sustainabe curricular resource that was designed in resp:,nse toconsistentstudent surveyfeedback req uestingsmall, interactive,

the university. cases are develoP3d byan interprofessional faculty team. Scenarios integrate learningobjectWes aligned

1M"l'l lnrnnon B:Uty e::$1itatirs n-.rk Brooks. Ph.D. (SOda Wot10,.n:I Din ~epf(Ft'mn~)list>Yl as lheir te?n 1M"l'l lnrnnon B:Uty e::$1itatir Biz.be ti <r.rnpsey1iswis as t8'

rnfnbErS <heisea ~ldl <P~ ~ - .'1 7)..oJ.nna ~.n (SOda Wotk.'17).~gail Fa-rid< ~a,,,paliCN lhEt<IPY.'1$, rltlirde .o.d(libigbe <J't¼ical lhEt<IPY.'17),.n:I Pallid< NJrpaska(<O M,¡1~ i " ' in en tie I ~ )

intErp-oeSional \?.rn,''Olle'.' v.oks lhmigh aoo~icated case

dsrus:s ao:rn~e<case.

93 I centers for excellence I RISll'IC TIDE

to present theirc umulatWe know led~ in a collective project presented at the end of ea: h semester.

Instructional formats include team-buildingexercises, case-based learningand simulations that highlight difflcultconversations in areas of disabilityand sexuality, falls prevention, work with otler adults and veteran's health care. Future sessions will tackle complexelementsofaddiction and mental illness.

IPTI metho::lologyutilizes a rapid-cycle evaluation scheme wherebystudents fill out feedba:kcards that are collected, reviewed and used to ma~ improvements in subsequentsessions. Overall findings indicate that I PTI students a:lvance in their awareness, understand ingand appreciation of how combining their expertise can be both extremely useful and, attimes,complicated. The majoritys~culated that they will apply th is learning in future clinical learning and employment.

Dental ~iene,oa,,,~cn~ ~.ipy.nU'Si"',.nd P\'Sid.n asSis wit ~~ts h.irry ~ blild h ~lest 1:0M:f' in .n inb3'profesSional aci"'tv deSigned ~ Sim.ilateMnwetk sld1s 1Jrder1ight lirneo:nwaints.

IPTI p:artCip:ants are actWetyenga~d in their learning, teing toth recipients and pro::lucers of knowledge.

Simulated interviews with well-prepared "patients" offered a rich pre-clinical platform toexperiment with new know led~ and to toth test and receive

with Core Com~ncies for lnterprofessional Pra:tice ~16)thataim to increasestudents' underst:andingof

critQue oncapa:itesto ~rform aseffectWe heath care

ea:h other's roles and resp:,nsibilites, hone teamwork

team memters.

skills, refine cross-professbnal communication, and incorp:,rate factors that providers typicallyencou nter in real-world pra:tCe. The majorityofstudentsopt

Waoc h the facultyand student feedbackvideoat https://youtu.be/SOVRLeq eaaE . •

·1t1e <oH<ibcn~rs;·1ett~ tight Eritlney Stell (l). MD..'19), dltiSina<u,-y~o P.'1 7), Oinm some (FhysicarTher<IW,·1~ LalJra Klmey(~cnai lhEf'<IPY.'1 7A.n:I Signe Mexn!Er $:Ida! WUk,'1$dg-ncns1fatehCM' ~ p-o,..je e:.a:pliOM p~ntOE'f'l ~l)?g«e,co P,'1 7)cn IJSingbOlh \'Elba! .nd ron\'Erb<il o:rnm.ilicalicn as p;r"t Off'le lntErp-o~SioM ~.rn tnrnersicn pos\?rsesSicn.

R1S1NC TIDE I centers for excellence I 94

UNÂŁ EhactJs Pn?sidrslt trewTurrb<ill (9.6iness,'2Qlleads ~drslts trolth aeali~ &14dses 1:0 design p)Wlii<il hefletotffirts sa1Jli0ns 1:0 heip p-o\?d

Main(!S roast ftffl'l tie Mt.J~ns tlatM\'e re::ien~ tainted local she11!am.

UN E's Makerspace,an innovative campus resource that serves as a latoratoryfor creation and building,

was opened in thespringof2016, thanks tothe inspiration and generosity of many. Things have teen ta~n toa whole new level th is fall,as the Ma~rspace is off to a great start- more than doubling both the

SUPPORT Of RESEARCH PROJECTS MORE THAN DOUBLES In add ltbn to the classes, much of the focusofthe Ma~rspace is on supportingbroad and deep student

numberof student research projects and the numter of students in the Ma~rspa:e Cluband a:ldinga new social innovation clubcalled Ena:tus to helpdevebp ideas leading upto the Innovation Challen~.

SOCIAL INNOVATION AND ENTREPRENEURSHIP CLASSES At the center of the space are interdisc iplinaryscc ial innovatbn and entrepreneurshipclassesthatare fee used on solving world problems with student Deas.

The classes are made upofstudents from all majors

who learn test pra:tCes to dissect problems,come up with ideas,and learn Wa'fS of prototyping and testing those ideas, including how to make those ideassust:ainable through entrepreneurship.

95 I centers for excellence I RISll'IC TIDE

F'aitl P~ier<ili Q).liW WIMr.'l&)v.uksv,Uhotler~drsltscnb.iild"' abetwoo1.1Sell".iptohelp 1radÂŤn ell~erejspedes.

to identifytrees.Also,a new social innovation club has teen started in the Makers pace ca led Enactus.

Its mission is toenga~ and em p:,wer others to ma~ impa:ts through innovatbn and entrepreneurial

action. The club has alreadystarted pilotingsparking sessions, thinktanks and quick pitch com~titions to helpstudents come up with and develop ideas to help with Maine problems, eading upto the Spring Innovation Chalenge.

STUDENT INNOVATION CHALLENGE SETS GOAL TO DOUBLE SUBMISSIONS The U NE Student I nnouatbn Challenge is based in the Makerspace and open 1o UNE students of any 9'1.idrslts wuk en r.ipkl P"°'°t\PE!S 1:0 he1pflght tie MY~c..:gae tm lit tie coast Of M~ne t.s pasH..:I.

research ~oject:s. Students from manydifferent majors are working on projects ranging from rovers in the

major. UNE's Student Innovation Chalenge is an ide~sta~ com~tition that encourages innovative and sustainable solutions to social, environmental and health issues facingour society. Winners receive

ocean that can help with research on wa}IS to ~ep the oceans healthy,1o buildinga better mousetrap that helps tra:kendangered spec es, to creating

cash and supp:,rtawardswith ho~s ofadvancingtheir

devCes that help with neuroscience research.

students. Throughout the fall and springsemesters, the Ma~rspa:e will offer workshops,seminars and

STUDENT CLUBS DOUBLE

aeas 1Dthe neo<t evel. Studenis can participate whether theyare undergra::luates,gra::I uate students or on line

mentoringto helpstudents spark and developtheir ideas and prepare for the Innovation Challen~.

Students earn through maklngwhile havingfu n, especially in the th rivingMakerspace Club. The club~

Anyone interested in learningmoreatoutthe UNE

projects thissemester have ran~d from arttosewing,

Innovation Chalenge or UNE Ma~rspa:e can email

to makingseasonal decorations, toe reating plaques

Tony Santella atasantella@une.edu. •

R1S1NC TIDE I centers for excellence I 96

Created in X:.16 by com bin ingthe 1brmer Center for lnterprofessional Education with several UNE public

I feel more confldentand comfortable having an a:tive role in the discussion of the patient's care.''

health programs, the Centerfor Excellence in Health Innovation collaborates with UN Efaculty, students and community partners in the transforming nexus tetween health care, pu bit health and education. As a result, the center provides innovatWe interprofessional earn ingopp:,rtunities to UN Estudents, research opp:,rtunities forstudents and fa: ultyand outrea: h in our communities.

Since partofthe interprofessional training includes medical and pharmacystudents jointtyvisiting patents with complex health issues in their homes, O'Meara notes that ''the experience also gave [her ]a unique perspecti\!e: that of the patents, when they are in a vu lnerabe positbns,such as in a clinic office or newlydischarged to their homes with new diagnoses and medications."

Thecenter's interprofessionalopp:,rtunities uniquely fee us on those in clintalsettings that irwolve students

from UNE~ Colege of Osteopathic Medicine and other UNE health professions programs. D:lra Anne Mills, M.D., the center'sd irector,eo<plained, "Through these learninga:tivities we are strengtheningour relationships with clinical affiliates, buildinga health

Overall, O'Meara notes that"the ex~rience gave [her Iinsight into the challenges facing health care providers in coordinatbn of care and assisting patents while under the care of multiple providers and an appreciation of the team-based approa:h to health care:'

workforce pi~line to underserved areas in northern RURAL HEALTHIMMERSION

New England, and helpingtotransform the way health care is practiced.''

Attr3:ting health care professionals to rural and

CLINICAL INTE RPROfESSI ONAL EDU CATION

1bra num terof years - and even more so now that

underserved communities has teen a priority at UNE Maine is notonlythe otlest butalsothe most rural state in the nation. To provide rural health ex~riences tostudents early in their education, UNE's Center for Health lnnouation has collal:orated with facultyand clinical partnerstooffer rural health inter professional immersions for students.

In May X:.16, 15students - an equal number from UNE~ colleges of Osteopathic Medicine, Dental

Mchel)? O'MN'a, Ph;,rn.D.,'14

Before graduatingfrom UNE, Michelle O'Meara, Pharm.D. '14 participated in a clinical interprofessional trainingsite in X:.13 at the Family Medicine Institute, a family pr3:ticeafliliated with Maine General Health in Augusta. This Advanced Pharma:y Practte Ex~rience (APPE) included learningactWites and seeing patients with a medical student from UNE~ Colegeof Osteopathic Medicine.

Now a pharma:istat Hannaford Pharmacy in southern Maine, O'Meara found herclinical interprofessional ex~rences veryvaluable. She recently reflected, 'When discussingtreatmentoptions with physicians,

97 I centers for excellence I RISll'IC TIDE

~ne Mruse REp'esentali...e Jdln Mrin .n:l 1011'tQ' Maine State SU'l~ JI.Ot' P.tadsjC.ned h 111al inrnErSicn trOlP tlrbt'M<tastat

tie ~nli"' ¢,rell¢,Of Rrute 110 dSOJSs state aid ildE'f'<11 pdio., .n:I its inp~cn111ai ~ti.

Medicine and Pharma:y- sP3nta week in Aroostook Countywith Mills, Jennifer Gunderman, M.P.H., assistant lecturer in the School of Com mu nityand Population Health, Jenifer \rcln Deusen, M.Ed.,and center st,iff member Ian Imbert, B.S. '12, M .P.H. '15.

Wesley,,n Doibner (COM, '18)said,"Thiseo<perience helP3d me solidify my interest in practting ruraldental medicine. For instance, we traveled to Van Buren to P3rform bast dental screeningswith medical students on elementaryschool children and provided them with fluoride varnish and oral health instructions."

Sam Wood (COM, '19)observed,'We not only earned a great deal from, with and atoutea:h other, but we also earned that the re is someth i ngtr uty sP3c ial atout the rural comp:,nentof this place in that it is a true community. The P3ople here all know ea:h other, their kids know each other, they run into each otheratthe local ice cream shop,and they leave their keys in the car without fear. Most imp:,rtantty, the health care system a:tsas an integrated and functbnal unit... tecause it has to. Everycomp:,nentand everymemter of the health care team is essential, and this fa:t is crys ta I clear in th is environ men t"

<UPsch:tl.rs p.r1i~atein iM?l'J)'O*s:s,:,nai INnngaci-.tiies t,o.,sied on tie

c.,1"' fCt' UldrfiEMid pcplJaliens

a:tivities provide the comP3tencies necessary to provide team-based, qualitycare forvulnerable patents at underserved locations in rural and urban Maine and te~nd. Fa:u ltyinvolved in CUP also serve as p:,sitive role mo::lels and mentors.

Dora Anne Mills, M .D., M.P.H ., FAAP, director of the Center for Health Innovation, discussed the variety of servte earn ingactivities offered to the students, including influenza vaccine clinics in homeless shelters and veterans clinics, one-week rural immersions, nutrition education among low-income Mainers,and opp:,rtunities 1brclerkships in a variety of underserved urban, rural and international locations. Said Mills, "All of these and other a:tWities

UNÂŁ SMEnl:S <Yid Dera Pline MIis awend 10gelher en tiee.-iy mcmi"' fllw en lhe local Aroo~ktr:le.tsien s~on,WAGM.

CARE FOR THE UNDERSERVED PATHWAY UN E's Center for Excelence in Health Innovation and the Colle~ of Osteopathic Medicine (COM) launched the care for the Underserved Pathway (CUP) in the fall of 2016. The inaugural class of 14 second-year medical students from the Class of X:.19 participate in interprofessional earn ingactivities fee used on caringforthe underserved. These

are provided interprofessionalty, mean ingalongside students from other professions such as dental medicine, pharma:y,social work, nu rsingand the physician assistant program as well as with the patent as a memter of the team,since that is how health care is mosteffectWelydelivered - as a team.

My hope is that by proua ingthese opp:,rtunities lbr our students, not on tywill ourcommunities teneflt from their service but even more of our students will choose careers in underserved bcatbns.''

The fou r-}ear Care of the Underserved Pathway (CUP) program coordinates cu rrentand planned offerings in underserved care and combines them into a comprehensive pathway designed toensure that rising physt ians will provide qualitycare for underserved patients in Maine and beyond. a

R1S1NC TIDE I centers for excellence I 98

•

..

Septemter is recogn ize::I an nuallyas Pain Awareness Month and National Recovery Month. This September, the UN EPain Education and Advocacy CollatoratWe (PEAC), in partnershipwith the Chronic Pain Support Groupof Southern Maine, the Biddeford Chapter of Young People in Recovery ('(PR) and the US Pain Foundation, hosted a series of events and awareness campaigns with the intentbn of reducingstigmas associated with pain and substance misuse, while

engaging the community in diabgues tetween the UN£ tao.,1ty .n:I sUent<f't'I.Q'kat °'he ~ores chroricpain, slbswioernisllSe .n:I reoMS'\I

pain and recovery p:,pu lation. Events included an art exhibition, proclamation readings from local city mayors, a com mun itystorytelling night and an

•

interprofessional panel at UNE. The collatorative aimed to host a varietyofevents ap~alingto students, fclcultyand community memters with vared interests in patientad\/Oca:y,chronic pain, recovery and improving medical outcomes.

o) Jenn t-uon, UN£ <enw ot ~1en::e in tie f>.)llJrosdences,ad'nires ··r.sb

<•·: aeated by Ally DeilU"l'IEri (~ti,WEiiness .n:I 000,,palimal

StJdies, '15)

The collaborative aimed to host a variety of events appealing to students, faculty and community members with varied interests in patient advocacy, chronic pain, recovery and improving medical outcomes.

September kic~d off with the opening night of an artexhibition titled "Pain Unplugged: Honoringthe Emotional JourneyofChronic Pain and Addiction."

Local oonrnUlityrnernber FtlHy f>.mdh swids in t'cntot.n lrdiaink

<!'M"' .nd a watErCOlct' she o:niribllted 10 h

dr

edlibit

Eri~ Penrod (Public Health, '18)/a:ilitated the opening, held at Engine, an artspa:e in Biddeford, Maine, that includes a gallery, acommunity ma~rspa:e and studios where it offers classes and workshops. To curate the colectbn, PEAC issued a call fora rt submissbns,encou ragingstudents, ta:u ltymem ters and comm unity memters to share artwork that they had created representing pain,addiction or recovery.

This exh ibitbn provided artists with the opp:,rtunity

1osell and displaytheir art, which created feelings of lhe <l'tedli~t .n:I nigMot~ryteHhg YMehud at °'ine in dov.nb<.n E!iddetlrd.

101 I researchandscholarship I RISII\CTIOE

self~mp:,wermentand a sense ofsolidaritywithin the community. Participants recu rrentty made comments

·'lN'drops"by M.m.h M:Oehee ,beimgs 1:0 a l.rger p-oje;t ··u~ng Fitrcrny;,g;a <ornm.ilicali"' <hn:nic P~n tirolth Art .n:I N.rrall...e.··

E!id:lefo'd ~ r .oJ.n<as~readsap-od.rnallmrec:o&niii"' SiepWl'ber as P~nA"""'1ness Mmtl.n:I Nallm<il ReoMryMmfl, v.H1e saco City M.Vlqs- Ke.in S1Jlhet1.n:l 1ooks m.

like,"I alwa}'S thought, who would want to see my ~rsonalartdepctingsu:h depress we pain?" Sentiments Ii~ these provide examples of the stigma associated with those whoex~rence chronic pain - exactly whatPEAC is tryingtoeliminate. Duringtheexhibition,

The second e.ent, facilitated by Samantha Shepard, A.A., (Bbmedical Sciences, '17), was a storytelling night,alsoat Engine, featurings~a~rswhodetailed theirexperiences with either chronic pain or

Biddeford Ma}Or Alan Casavant and Sa:o City

long-term recooery. The eveningwas designed to build bridges and encourage the vewingcommun ity

Mana~r Kevin Sutherland rea::1 a prcclamation recogn izingSeptemter as toth Pain Awareness

toconscler the mu ltHaceted asp:cts of these diseases. Otten, the mediac hooses to highlight the

Month and National Recovery Month. Subsequently,

negative stories associated with opioid misuse while

comm unity memters were encou ra~d to explore and contemplate the emotions and pers~ctives of

stories of successful recovery from drugmisuse and

~ople livingwith pain,addictbn and recooery.

group and YPR-Biddeford chose to honor stories of

successfu I pain treatmentare neglected. The PEAC resilency, humanityand healing. Engine was the

During the exhibitirn, Biddeford :Mayor Alan Casavant and Saco City :Manager Kevin Sutherland read a proclamation recognizing September as both Pain Awareness :Month and National Recovery :Month.

~rfectvenue,as its neutral environment allowed for o~n conscleration,and the "Pain Unplugged"art

eo<hibit helped to set the mood and encourage meaningful conversation and contemplation.

The storytellinge.ent featured five speakers,each of whom drew from their ~rsonal ex~riences with eitherch ronic pain or long-term recovery. The group

included: Jess1br Baugh, B.S. '13 (COM, '17), Kevin Sutherland (Sa:o City Manager), Elizabeth Sprague

RISIHCTIDE I researchandscholarship I 102

(Health, Wellness and Occupational Studies, '19), Matthew Braun (Chapter Leader, YPR-Biddeford) and Andrew Kezu las, (UniversityofSouthern Maine student). Using a popular PechaKucha format, each s~aker led the audience on a six-minute, 40-second journeythat incorporated X> ima~s thatautomaticallyadvanced every20seconds. These talks were highlyemotional and evoked a deepconnection tetween the s~akers and the aud ence memters. lntermissbn included a 1~minute film, "Hooked,"

which portra}ed the story of a high schooler who develops a substance abuse disorderaftera serious injury. "Hoo~d"was created in totality by high school students in\lOWed with Project Aware

~ww .projectaware.net/).

This interprofessional panel was designed to facilitate discussion among student health professionals from different programs regarding two pre-selected chronic pain cases.

103 I researchandscholarship I RISII\CTIOE

Fort he final event, Lindsey Simmons (COP, '19), working in collaboration with Kris Hall,coordinator of the lnterprofessional Education Collaborative,

organized a vared panel of health care professionals who discussed topics such as c hron t pain, pain treatment, opioid use and mis use, and interprofessbnal communication. The flrstexP3rt panelistwas Merideth Norris,D.O.,an osteopathic physician who is board certified in addiction medicine. Norris directs an intensive outpatient program and a methadone clinic in addition to ru nningan outpatient pra:tice in which she manages manyconditions, including pain.

The second panelist, Jessica Bates, Pharm.D., is a pharmacistat Penobscot Valley Commun ityHealth care, where she provides controlled substance stewardship. The final panelist was Kelli FCD<, LCSW, a clinical sec ial worker, who has teen in the field of mental health and addiction since 1985and has focused her clinical pra:tice on co~ccurring disorders of PTSD and substance use,ch ild-parent attach mentand tondingand fam ilytherapy.

This interprofessional panel was designed tofa: ilitate discussbn amongstudent health professionals from

different programs regardingtwo pre-selected chronic pain cases. As a surprise to the students, rre mte rs of the Southern Maine Chronic Pa in Su pp:,r t Groupwere pla:ed in manyofthestudentgroups, allowingstudents to gain a firsthand understanding of the needs and ideas of those livingwith chronic pain. Notably, students reflected on how much they enpyed working and interactingwith the chronic pain patients as opp:,sed tosimply readingatout their cases in a traditional classroom setting. The eventaimed tosparkconversation amongd ifferent health professionals a tout fu Hy incorp:,ratingthe patient into the treatmentand care plan ma nag&

1tida G.t'rett ~ysid.n Assiswit·1&)te11s lhe<1Jdi\ori1Jrn v.hather grrup -in:::llldngRcb F'Oley.a~.nv,Uhj»n -finks.bruta

mentdiabgue.

OO'l'l~e.ccase.

Traditionally, pain and recoverya:lvccacy groups have wor~d separately. However,an interesting partnership 1brmed due to the d iscoueryofthe similarchallenges and missions of both groups. The intertwin ingof spiritual,emotional and physical pain between both health conditions,and the concept of resiliencyasa driving force to healingand overcoming hurdles, unites the p:atientexP3riences of toth groups.

Workingtoera:licate the stigmas associated with chronic pain and substance use disorders serves to

tetter educate and emp:,wer the com mu nityto help fight these diseases, which ha11e reached epaem i: proportions. In closing, PEAC, YPR-Biddeford and the Chronic Pain Supp:,rt Group of Southern Maine would liketoemphasize the S'Yflergistic effect of bridging the pain and recovery communities and express their hoP3 that these ideas willsprea:1 into othercommunities to make a p:,sitive impa:tfor those exP3riencingthese diseases. •

P.nelistsJesSica Bates,Ph.rm.D.• l<Elli Rrx,L<SW,.nl MEridelh Nuris. D.O.

RISIHCTIDE

I

researchandscholarship

I

104

The Universityof New England's Center for Excelence in the Neurosciences hosted its third annual Brain Fair on April 8, 2016,atthe Harold Alfond Forum on U NE's Biddeford campus. More than 500 students from b:al school distri:ts attended thee.ent, abngwith local families and community memters.

Theyenjoyed fun and engaging hands-on activities, presentations and exhibits intended to educate the comm unityaboutthe im p:,rtance of brain health and ouerall todywellness.

The event took pla:e during Brain Awareness Week, a worldwtle campaign launched bythe Dana Alliance for Brain Initiatives to promote neuroscience and ad\/Ocatefor science funding. The Brain Fair was part of a series of"'ents hosted byU NE during April to furtherthis mission.

Brain Fair attendees walked through an amazing collection of human brain samples highlighting healthy brains and brains affected by disease and injury.

They also 1bund neu roanatomydisplays,sheep brain dissections and microsco~ set-ups where theycou ti observe a varetyot microscopic brain pictures.

105 I researchandscholarship I RISII\CTIOE

Families also visited the "Bugs and Drugs"d isplay, which showed how chemicals affect the ner\/Ous S'YStem and insect tehavior. ln1brmation sessbns oo corcussion awareness, opoids, how we learn,ard the linktetween music and health were well attended.

Professional athletes joined UN E studentath letes to offer demonstrations revealingthe link between neurosc ence and athletes. The event included presentations by Olympic gold medalist Di: kFosbury, known 1br revolution izingthe high ju mpwith the creation of his ba:k-flrst jum pingtechnique, as well as Main&based professiooal taxer Brandon '1"he cannon" Berry and UNE Motion Analysis Lab Manat"r Mi~ Lawrence, M .S., the 18th ran ~d power lifter in the United States.

The bicycle helmet-fitting presentation and giveaway, sp:,nsored by the Michael T. Goulet Foundation, was once again a highlightof the event. The foundation is a Maine-based non-profit organizatbn that aims to increase awareness, prevention and improved treatment for seizure disorders and brain injuries.

Geoff'ey Gner, Fh D., p-otessorofbiaogy.tens sUents .boot tis ~n rese<l'Ch. on SO'&"Sl is \tl1.ill.1be '-'deo ''<M°'lie Bit My Finga-:â&#x20AC;˘

Discussingthe event, Michael Burman, Ph.D.,asscciate professor of neuroscience and facultycoordinator for the UN E Center 1br Excellence in the Neu rosciences K-12 Outreach Program,eo<plained, 'Wewant1oshare with the public how amazing the brain is and how imp:,rtant it is to keep it safe. It's soc ritical for every aspectofour life and yet also sofragile.And yet, we krowso litte atoutthe brain, from l:oth the perspectwe of basic science and treatingdisorders and injury. We ho~ this exhibit will inspire more ~ope to study neuroscierce, includingthrough oor excellent programs at the Universityof New England."

Ed Bils~, Ph.D., UN Ev ice president for Research and Scholarship, said, "Neuroscience-related topics are in the news everyday and have teen in the public consc busness and discussion this past ~ear. Topics from concussions to opioid abuse, to diseases that impact the aging brain are so critically imp:,rtant to our so:ietyand its health. UNE isa leader in educating physC ians and other health care professbnals, and our ex~rtise in the neurosc enc es allows us to bring world-class exhibits and demonstrations to the school systems and public in Maine." a

<cn~rui"' edlalicn ~OYlt .n:I Q:IIJet F'rurdalicn Sctol.rslip IMmer Midlar:t <\f' e:.plains tie irnporw.:e ofp-otei;ing,.oll' brain by O'cpi:-"' a rneicn wifl .n:I IMf'lrut aheirnet

RISIHCTIDE

I researchandscholarship I 106

ChronC pain is a complex, multita:eted and devastating condition that more than a million Americans suffer from each day. As a result, billbns of dollars are at riskannuallyin medical costs, lost wages and care.

The Uni\!ersityof New England is at the 1brefront of addressingthis growingeptlem C through increased pain education in the Colege of Osteopathic Medicine, to~tier research and com munityoutrea: h in the New England chronic pain comm unity.

On August 3, 2016, UN E~ Office of Research and Scholarship hosted a pain summit, inviting researchers, osteopathC physicians,clinicians,educatorsand p:,licy creators tovisitcampus. The top Cs addressed that

dayincluded issues involving patient care,education, p:,licyand advccacy,and attendees shared new and innovative approa:hes totreatingchronic pain.

Among the sP3a~rs were Daniel Carr, M.D., Tufts University; Jon Hamilton ofN PR; Sean Mackey, M.D., Ph.D., Stanford University; Jon Levine, M.D., Ph.D., professor of medicine at UCSF;and Linda Porter, Ph.D., National Institutes of Health. Local eo<perts included Brain Kaufman, 0.0., FACOI, FACP, Total Health and Spine; Y\!es De Koninck, Ph.D., FCAH S, FRSC,scientiflc directorof Quebec Mental Health

107

I

researchandscholarship I RISII\CTIOE

Institute; Ling Cao, M.D., Ph.D., professor in the UNE COiiege of Osteopathic Medicine; Bill Paterson, M.Ed., CPE, PS-C, directorofCoastal Healthy Community Coalition; and Jane Carreiro, 0.0., dean of the UNE College of Osteopathic Medicine.

The talks addressed ever}'thingfrom basic patient interaction to the concurrent issue of substance misuse, to neurobbbgyand mechanisms of pain circuitry. An exP3rt panel, featuringCongresswoman Che Hie Pingree,addressed the currentstatus of national p:,licies 1bcusingon chronic pain and fielded questions from pain patients, research scientists and eo< perts in the fie Id. Throughout the day, U NE students shared their research through p:ister presentatbns that revealed the cutting~d~ research teingconducted in UN E's laboratores. The p:,sters detailed research into differenttyP3sof pain,sccblogCaltrends, P3rceptions in the health care industry; cancer-induced pain and the effects of neljnatal pain.

The event prouaed a platform for thoughtful discussion of the manychallenges associated with treatingchronic pain. Along with exploringoptimized

treatments 1brc hronic pain, partCipant:s grappled with the pu bit's growing opiate misuse and the need for alternative pain treatment approaches. UN Ewill

_._,~

.......

------

~he <cngres:sv.ÂŤl'l.n <heme Angree dso.,sses tie o:rn~eo1ies Of

tie oi:-oid ad:lie1icn ei:-demc.

continue tofa: ilitate discussion while bringing its resources and innovative approaches to tear in the questtotreatchront pain and reduceopia1e addttion.a

RISIHCTIDE

I researchandscholarship I 10S

Castigliano M. Bhamidipati, D.O. '06, Ph.D., MS.c.

Alex Skorput. Ph.D. '08

Alexa Lopez, Ph.D. '09

(Biomedical Sciences)

(Psychobiology)

DID RESEARCH WITH: Ed Bilskyon novel

DID RESEARCH WITH: Ed Bilskyon basic

DID RESEARCH WITH: Ed Bilskyon

compound development to fight opioid abuse

pain pathophysiology

opioid pain pharmacology

CURRENT CAREER: Finishing a

CURRENT CAREER: Postdoctoral fellow

CURRENT CAREER: Research psychologist/

cardiothoracic fellowship in Seattle at the

at the University of Minnesota, researching

principle investigator with the U.S. Army

University of Washington and planning to

the pathophysiology of neuropathic pain

enter a new chapter of life in academic cardiac surgery The lab experience taught me that research

Medical Research Directorate-West, part of the Walter Reed Army Institute of Research

Dr. Bilsky made a point of teaching his students how to communicate the work we

I wholeheartedly believe that without my

were doing with others, through both the

research experiences at UNE, I would have followed a much different path. While I have

is about basic understanding, logic,

presentation of work at scientific meetings

communication and impacting the communi-

and the constant introduction of students to

always been interested in scientific knowledge

ty. At a basal level it was also teaching me

visiting scientists, technology professionals

and validation, having the opportunity to be

how to ask the right questions, test

and senior administrators. Through this, I

directly involved with research at such an early

hypotheses and challenge contemporary

was taught how to clearly communicate

stage of my career was critically valuable. I

thought.

complicated topics and was left with the

strongly encourage all students who are

109 I student snapshots I RISING TIDE

knowledge of how to conduct myself in a

interested in pursuing graduate education -

scientific profession. These lessons could not

or any other research-focused career path -

have been taught in a classroom and have

to seek out one of the many opportunities

proved invaluable in furthering my career.

that UNE has offer.

Richard Feeney, D.O. '09

Ashlee A. Robbins, B.S. '08

Tom Miller, D.O. '07

(Medical Biology and Biochemistry) DID RESEARCH WITH: Ian Meng on

DID RESEARCH WITH : Ian Meng on

DID RESEARCH WITH: AmyDavidoffon

medication overuse and headache

headache and general medication overuse

cardiomyocyte cell biology

CURRENT CAREER: lnterventional

CURRENT CAREER: PhD.candidate,

CU RR ENT CAREER: Assistant professor

physiatrist in Exeter, NH

Dartmouth's program for Experimental and

in the Department of Pediatrics in the

Molecular Medicine

Division of Pediatric Cardiology at the University of Utah

I left the laboratory with a greater appreciation for the tireless work our basic research

There was a pretty tight-knit research group

scientists pour into the pool of knowledge,

in Stella Maris at the time, so we got

Being associated with a lab kept me engaged

which in turn, influences our treatment

exposure to a lot of different kinds of research,

with scientific thinking/approach/critique to

paradigms. I believe it gave me confidence in

from Ian, Ed, Ling and Dave Mokler's labs. Going

a level you don't get with standard course-

critically evaluating the research behind our

to diverse seminars and learning to think

work I would enthusiastically encourage others

decisions. This experience definitely guided my

critically were aspects of working in the lab

to participate in research at UNE. Being a part

path beyond UNE. Choosing physical

and were really important for getting ready for

of research is the best way to understand how

medicine and rehabilitation, and then

grad school. It gave me a diverse background

the biomedical sciences advance and what

subspecializing in pain medicine, was a

in a lot of different research techniques.

data (or more often lack of data) drive

natural extension of the curiosity stoked by

medical guidelines, opinions and decisions.

this early research exposure. I believe it made me a more competitive candidate and, more importantly, a more thoughtful physician.

RISI NG Tl DE I

student snapshots

I 110

INNOVATION FOR A HEALTHIER PLANET 11 H ills Beach Road, Bidi?fo rd, ME 04005, U.S.A

INNOVATION FOR A HEALTHIER PLAN ET