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tional Bubble Microrobots

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“Integrated Assembly and Flexible Movement of Microparts Using Multifunctional Bubble Microrobots”

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ACS Applied Materials & Interfaces

Robots are widely used to build cars, paint airplanes and sew clothing in factories, but the assembly of microscopic components, such as those for biomedical applications, has not yet been automated. Lasers could be the solution. Now, researchers reporting in ACS Applied Materials & Interfaces have used lasers to create miniature robots from bubbles that lift, drop and manipulate small pieces into interconnected structures.

As manufacturing has miniaturized, objects are now being constructed that are only a few hundred micrometers long, or about the thickness of a sheet of paper. But it is hard to position such small pieces by hand. In previous studies, scientists created microscopic bubbles using light or sound to assemble 2D items. Also, in a recent experiment, microbubbles produced by lasers, focused and powerful beams of light, could rotate shapes in 3D space. Although these bubble microrobots could manipulate 2D and 3D objects, they could not connect independent components and then move them as a singular entity. So, Niandong Jiao, Lianquing Liu and colleagues wanted to build on their previous work with lasers to develop bubble microbots that can form inseparable shapes and control their movement.

The researchers created microbubbles in water by focusing a laser underneath a small part made of resin. The bubble’s size was controlled by rapidly switching the laser on and off, with a higher amount of time in the “on position” resulting in larger bubbles. Then, the team made a mobile bubble robot by shifting the laser’s location. Once the laser turned off, the bubbles dissolved slowly, dropping the resin in place. The team then combined multiple bubbles with different functions to produce microrobots that could lift and drop parts, move single pieces to designated positions, act as a rotational axis or push assembled objects. Unbreakable connections were made with various joints, producing three- and four-pronged gears, a snake-shaped chain and a miniature 3D vehicle. The bubble microrobots have implications for the future of manufacturing, including biological tissue engineering, the researchers say.

The authors acknowledge funding from the National Natural Science Foundation of China, the Key Research Program of Frontier Sciences of the Chinese Academy of Sciences and the CAS/SAFEA International Partnership Program for Creative Research Teams. https://youtu.be/e6xqh2YuoBY

DFW Section of the ACS 2021 Chair Trey Putnam

Professor Putnam was born and raised in Overland Park, Kansas, USA. He attended Pittsburg State University where he majored in Chemistry and conducted research in polymer chemistry. He was also an NSF -undergraduate research fellow at the University of Oklahoma where he conducted research in X-ray crystallography under Prof. Dick van der Helm. Dr. Putnam then attended Washington University in St. Louis where he earned a M.S. and Ph.D. in Organic Chemistry under Prof. James K. Bashkin. His research focused on the design and development of artificial ribonucleases as potential novel infectious disease therapeutic agents. Dr. Putnam then moved to the Midwest Research Institute where his research focused on the pharmacology candidate therapeutic agents including developing sensitive analytical and bioanalytical methods. Additional research interests included biomarkers of polycystic kidney disease, catalytic antibodies, and artificial ribonucleases. Dr. Putnam then took an appointment at Texas Tech University Health Sciences Center as an Assistant Professor in the School of Pharmacy. He also served as the laboratory director of the Pediatric Pharmacology Research and Development Center. Dr. Putnam then moved to Cardinal Health’s Scientific and Regulatory Consulting Division where he provided drug development/regulatory consulting to numerous pharmaceutical companies. Dr. Putnam eventually assumed the role of general manager and was responsible for strategic, managerial, and operational aspects of the business. Following his tenure with Cardinal Health, Dr. Putnam returned to Texas Tech’s School of Pharmacy as a Professor where he remains today. His current research interests include: clinical pharmacology, differential metabolism of disease states, biomarker identification/validation, and advanced analytical/bioanalytical methodology.

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