enlighten Product Brochure

Powerfully Versatile PICO Technology

PICO Revolutionized Removing the full range of tattoos, pigment, and other aesthetic concerns requires the ideal combination of technologies—the right wavelengths, the right pulse durations, and the right energy levels. enlighten III features three fully-integrated wavelengths, including the first truered picosecond wavelength, and industry-leading specifications that address: • • • •

Multicolor tattoos & benign pigmented lesions Epidermal and dermal pigmented lesions PICO GenesisTM for skin revitalization on all skin types PICO GenesisTM FX for acne scars and skin quality concerns*

Unparalleled Power

Fully Customizable

Maximum ROI

>20% higher than the competition1

3 fully-integrated wavelengths

No consumables or disposables

Up to 40X shorter than traditional pulse technology1

Dual pulse durations†

Fast warm-up time

Spot sizes up to 10 mm†

Multiple treatment applications

Independent control of fluence

†Available on 1064nm

Nearly 1 in 4 individuals experience tattoo regret.2

40% of the population susceptible to pigmentary concerns and 71% of consumers are seeking tone and texture improvement.3,4

Around 95% of individuals with acne will experience scarring5

Unrivaled Technology.

Proven Outcomes.

Selectively Chosen Wavelengths enlighten III’s wavelengths provides high absorption 1064 nm

670 nm

rates to treat the most common ink colors: black, red, blue, and green. The 532, 1064, and 670 nm wavelengths were chosen for their effectiveness in targeting a broad

532 nm

spectrum of colors and various skin types.

Optimized Pulse Durations Matching pulse duration to particle size helps you achieve faster, more complete clearance in fewer treatment sessions. enlighten III’s dual pulse durations - 2 ns and 750/660 ps – treat varying densities and particles sizes NANO: Large particles respond better to longer pulse durations1

CUTERA

PICO: As particles become smaller, shorter pulse durations are more effective1

CO M P ET ITO R 1

CO M P ET ITO R 2

Pulse Energy (mJ)

800

Strong, Powerful Delivery

600

enlighten III delivers a strong, non-thermal photomechanical

400

effect by combining high peak power and ultra-short pulse

200 0

more efficiently than single-pulse duration systems.

durations to shatter the target at varying depths without causing damage to the surrounding tissue.

1064 532

670

755 532 1064 1064 532 Wavelength (nm)

785

Customized Delivery.

Beautiful Skin.

Low Risk, High Reward Pigment Removal Address benign pigmented lesions on all skin types with confidence and ease. From low-contrast lesions to denser lesions on darker skin types, enlighten III’s range of specifications provides the parameters needed to effectively remove pigmented lesions with a higher safety margin.

1064 nm

Brilliant Skin with PICO Genesis In just a few quick treatments, PICO Genesis utilizes dualdelivery treatment to shatter unwanted pigment and induce skin revitalization. Selectively shatter pigmentary issues with the 1064 nm. Deliver non-thermal, laser induced shockwaves for dermal disruption and remodelling.

Renewed Skin with PICO Genesis FX Enhance skin revitalization with a fractional approach to treat acne scars, skin quality concerns, and aging on skin types II-V. Its innovative MicroLens Array (MLA) creates tiny, gentle microwounds in the upper layers of the epidermis and dermis while keeping surrounding tissue unharmed for quicker healing.

enlighten III Results Tattoo Removal

Before

After 3 Treatments

Individual results may vary.

Photos courtesy of Erasable, Inc.

Pigment

Before

After 1 Treatment

Individual results may vary.

Photos courtesy of Kelly Stankiewicz, MD

PICO Genesis FX

Before

After 5 Treatments

Individual results may vary.

Photos courtesy of Chen Hung Lee, MD

PICO Genesis FX

Before

After 1 Treatment

Individual results may vary.

Courtesy of Woraphong Manuskiatti, MD

Technical Specifications Wavelength

532 nm

670 nm

1064 nm

Pulse Energy

Up to 400 mJ

125 mJ (nominal)

800 mJ

Pulse Duration

750 ps or 2 ns

660 ps

750 ps or 2 ns

Spot Size

Up to 10 mm

Up to 6 mm

Up to 10 mm

Rep Rate

1, 2, 3.3, 5 and 10 Hz or single shot

1, 2, 3.3 and 5 Hz or single shot

1, 2, 3.3, 5 and 10 Hz or single shot

Dimensions

36” H x 20” W x 33” D

MLA Technical Specifications Wavelength

1064 nm

Pulse Energy

Up to 4 mJ

Spot Size

≤200 μm (micro)

Pitch

0.5 mm

References: 1 Data on File 2 https://www.pewresearch.org/short-reads/2023/08/15/32-of-americans-have-a-tattoo-including-22who-have-more-than-one/ 3 https://www.alliedmarketresearch.com/tattoo-removal-market 4 2016 ASDS Consumer Survey on Cosmetic Dermatologic Procedures 5 https://www.ajmc.com/view/review-highlights-toll-of-acne-scars-on-patients-quality-of-life *The Micro Lens Array is Health Canada licensed for pigmentation and skin revitalization Indications for Use: The 1064 nm wavelength of the enlighten III laser system is indicated for: treatment of benign pigmented lesions on patients with all skin types (Fitzpatrick I-VI); tattoo removal for dark colored tattoo inks and for multicolored tattoos containing dark colored tattoo inks on patients with all skin types (Fitzpatrick I-VI); treatment of acne scars on patients with Fitzpatrick skin types II-V when used with the Micro Lens Array handpiece attachment. The 670 nm wavelength of the enlighten III III laser system is indicated for: treatment of benign pigmented lesions on patients with Fitzpatrick skin types I-III; tattoo removal for lighter colored tattoo inks, including green and blue inks, on patients with Fitzpatrick skin types II-IV. The 532 nm wavelength of the enlighten III III laser system is indicated for: treatment of benign pigmented lesions on patients with Fitzpatrick skin types I-IV; tattoo removal for lighter colored tattoo inks, including red and yellow inks, on patients with Fitzpatrick skin types I-III. Contraindications: Pregnant patients; patients undergoing treatment for skin cancer. Important Safety Information: The following treatment-related expected transient side effects and possible adverse events may occur during or following treatment with enlighten III: Discomfort; Immediate ashy change in benign pigmented lesions;Hyperpigmentation; Hypopigmentation; Petechiae; Purpura; Blisters; Edema; Erythemal Allergic reaction; Bullae; Scabs; Crusting; Texture changes; Infection; Scarring; Persistence of pigmented lesion; Incomplete tattoo removal; Paradoxical darkening or color change; Bleeding of ink into surrounding skin.

Warnings: Do not treat or treat over dysplastic nevi or questionable pigmented lesions. Only benign pigmented lesions are treatable. Accurate pre-operative diagnosis is very important to prevent treatments on malignant lesions. Precautions: Current medications (both routine and occasional use); Accutane - do not treat if taken in the last 6 months; Gold Therapy - may cause blue-gray discoloration; Photosensitizing drugs (Tetracycline, etc) - perform test spots and adjust parameters accordingly; Anticoagulants - may increase risk of purpura or bruising; Bleeding disorders; Vitiligo or history of pigmentary disorders, particularly tendency for hyper- or hypopigmentation; Herpes - heat from the treatment could induce a flare-up; pretreatment with an antiviral may be indicated; Wound infections; Open lesions - treatments should only be performed on intact, healthy skin; History of coagulopathies; History of keloid or hypertrophic scarring; Diabetes - may impede wound healing; History of seizure disorders due to light. Refer to the Operator Manual to view the laser safety labels of the product.

Intended for North American audiences. ©2025 Cutera, Inc. All rights reserved. AP1706 rG (03/25)

About Cutera Cutera was founded in 1998 by veteran laser and optical engineers who envisioned that technology should and could do more. We have since grown into a global leader of dermatology and aesthetics devices that appeal to forward-thinking clinicians who seek the next generation of performance, safety, and efficacy.

Cutera, Inc. World Headquarters | 3240 Bayshore Boulevard, Brisbane, California 94005 USA 888-4-CUTERA or 415-657-5500 | info@cutera.com | cutera.com