CUREO5 Premium Brochure EN

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Efficient, effective versatile

The CUREO ® software is CE-certified as a medical device and CUREOSITY operates according to the ISO 13485 quality standard. This ensures compliance with the strict medical and therapeutic requirements and guarantees maximum reliability.

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CUREOSITY |

Together we create innovation

• MedTech company based in Düsseldorf

• Founded in 2019: By those affected, for those affected

• More than 50 employees

• Together with our partners and customers we revolutionize rehabilitation

• Known from ...and many more

CURE OSITY (HQ)

Düsseldorf

Our locations

Düsseldorf

With CUREO® we revolutionize rehabilitation

• 2021 Launch of CUREO®1, the first VR therapy software by CUREOSITY

• One major software update every year since launch

• Most recent version: CUREO®5

CUREO® at a glance

What makes CUREO®5 so impactful

• More than 50 Virtual Reality therapy trainings for diverse therapy goals

• Gamification elements to increase motivation and engagement

• Flexible use in group, parallel, and individual therapy

• Individual therapy planning with the new Therapy Navigator

• Central data management and documentation in the CUREO ® HUB

• Transparent performance tracking through patient testing and data export

• Regular digital updates and access to the CUREO ® CENTER with training and product knowledge

More at YOUTUBE

300+ facilities trust in CUREO ®

Stylistic map display. For detailed location information, please scan the QR code and visit our website.

450,000+ therapy sessions conducted in 2024

24 countries, in which CUREO® is available

Challenges in therapy 02

”By 2035, approximately 1.8 million professionals will be missing. This corresponds to a shortage of around 35%. This shows that in the coming years and decades, the healthcare sector will face a dramatic supply gap that endangers people’s well-being.”

PWC Deutschland, 2022

Source reference: PWC Deutschland, „Fachkräftemangel im Gesundheitswesen: Wenn Pflege selbst zum Pflegefall wird“, 2022.

Therapeutic staff at its limit

• Growing annual demand for therapy (2022 vs. 2023)1

• +9% individual occupational therapy sessions1

• +23% group occupational therapy sessions

• +6% individual physiotherapy sessions

• Severe shortage of professionals

• By 2035 1.8M positions will remain unfilled2

• Already missing today in Germany:

• 26,000 occupational therapists

• 11,000 physiotherapists

• Every 2nd therapist wants to leave the profession

• Already, every 2nd to 3rd citizen in Germany is underserved3

1GKV-Heilmittel-Schnellinformation für Deutschland des GKV-Spitzenverband für das Jahr 2023

2 PWC Deutschland, Juni 2022, Fachkräftemangel im Gesundheitswesen: Wenn die Pflege selbst zum Pflegefall wird 3World Health Organization, „Rehabilitation 2030: A call for action“, 2017

The solution:

and versatile therapy with CUREO®

“2 out of 3 young healthcare professionals see digital technologies as a key factor in choosing their career and employer, and as valuable support in their daily work.”

PWC Deutschland, 2022

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Gamified therapy in Virtual Reality

CUREO ® is based on three central principles that drive therapeutic success: gamification , Virtual Reality (VR), and the concept of embodiment

Gamification uses gamified elements to increase motivation and therapy engagement. New incentives, milestones, progress indicators, and continuously rising challenges turn therapy into an immersive experience. Playful repetition supports motor learning, promotes movement progress, and leads to sustainable training success.

Virtual Reality opens new possibilities in rehabilitation. Studies show high effectiveness in neurological and motor therapy, as well as broad applicability in occupational therapy, physiotherapy, and neuropsychology. VR therapy increases attention, motivation, and is highly resource-efficient

At the same time, CUREO ® supports neuroplasticity — the brain’s ability to

form new connections and reorganize functions after injury or disease. Precisely selected visual, auditory, and motor stimuli activate different areas of the brain to optimally support learning and regeneration processes.

The final key principle is embodiment , the conscious perception and integration of one’s own body. Through the representation of a biomechanical avatar in virtual reality, patients perceive a healthy, functioning body in real time and develop a renewed, positive body image. This principle strengthens body perception , supports the coordination of sensory and motor functions, and contributes to improved well-being and quality of life.

CUREO ® brings these scientifically grounded principles together in one system that redefines motivation , effectiveness, and the joy of movement –in every therapy session.

„CUREOSITY aims to put a smile on patients’ faces, enable sustainable movement progress, and make daily use for therapists simple and efficient.

With CUREO®, we already achieve this goal today – and we work every day to expand the horizon of what is therapeutically possible.“

CUREosity GmbH | Chief Executive Officer Caesar van Heyningen

Acceptance and feasibility studies

Acceptance & motivation (1)

• 95% of patients are enthusiastic about CUREO® therapy.

• 97% would like to repeat it.

Feasibility in early rehabilitation (2)

• 76% report equal or higher motivation than with conventional therapy.

(1) Stemick, J., Kurth, J., Saur, T. (2022). Gesteigerte Therapiemotivation durch innovative Virtual-Reality-Therapie, Nervenheilkunde.

(2) Kühne Escolà, J., Demirdas, R., Schulze, M. et al. (2024). Virtual reality-guided therapy on a stroke unit: a feasibility study. Neurol. Res. Pract. 6, 60.

Clinical effectiveness

• 2/3 of therapists consider VR therapy easy to implement.

(3) Lülsdorff, K, et al. (2023). Neurorehabilitation of the upper extremity immersive virtual reality vs. electromechanically assisted training. A comparative study. Frontiers Neurology.

(4) Herwest, et al. (2024). Virtual Reality Treatment in a Neuro-palliative Care Unit. Neurology.

Arm rehabilitation after stroke (3)

• 84% of patients undergoing VR therapy show clinically relevant improvements in arm function.

• The extent of improvement in the group treated with CUREO® was significantly greater.

Improvement of quality of life in palliative care (4)

• Significant improvement in overall well-being.

• Significant reduction in symptoms such as pain, anxiety, sadness, or fatigue.

The scientific evidence for CUREO ® continues to grow

Completed | Published Initiated | Ongoing

Randomized controlled studies

Clinical effectiveness in Parkinson’s disease (5)

• A two-center randomized controlled trial investigating the effectiveness of CUREO® therapy compared to conventional therapy in people with Parkinson’s disease.

• Study is completed and since October 2025 in the peer-review process.

Treatment of visual neglect after stroke (ongoing) (6)

• Study participants receive either VR therapy with CUREO® or electromechanically assisted training.

• Therapy progress is measured via VR-based diagnostic screening and based on symptom improvement.

(5) Registered study DRKS00034193 (6) Registered study DRKS00034076

Integration studies

VR as part of modern care models

• Evaluation of innovative therapy concepts in real-world clinical settings.

• Pilot projects and partnerships focused on the integration of CUREO® into daily routines in clinics and practices.

• Objective: Sustainably improve therapy efficiency and overall quality.

“We are convinced that modern methods like CUREO® are essential in today’s neurological rehabilitation.”
AMBULANTICUM GmbH | Managing Director | Marion Schrimpf
More studies on CUREO® and VR
CUREO® is perfect for rehabilitation in inpatient clinics and outpatient practices

Perfect for clinics

Group therapy

The new and unique solution for the simultaneous treatment of up to 6 patients in your facility.

Perfect for practices

Parallel treatment

Make use of the efficient Training Plan function and gain time for additional patients or documentation

For clinics and practices

Individual therapy

Focus entirely on the individual needs of each patient.

The solution: CUREO ®

The advantages of CUREO ® for your institution

• Minimal set-up times thanks to rapid system start, easy calibration, and automatic connection.

• Smart features such as the Therapy Navigator and the Training Plan support therapists in planning and execution.

• The CUREO® HUB consolidates reports, patient data, and usage statistics and makes results available at the push of a button.

• Using modern methods increases your attractiveness as an employer for new and existing staff.

Effective

• Improved treatment adherence:

• 95% of CUREO® patients are enthusiastic.

• 97% of patients want to continue CUREO® therapy.

• 84% of stroke patients in a clinical study show clinically relevant improvements in arm functionality.

• Enhanced well-being and reduced symptoms in palliative care.

• The Passthrough functionality enables direct eye contact and interaction between therapist and patient.

Learn more about our studies on p. 20

Versatile

• 50+ trainings in one system for physiotherapy, occupational therapy, and neuropsychology.

• Use in group, parallel, and individual therapy - now even more flexible with CUREO® GROUP+1.

• Access to the CUREO® CENTER for training and practical knowledge in everyday therapy.

• Regular digital updates with new, improved, and expanded trainings and features.

CUREO ® for clinics

Developed with clinical partners, proven in rehabilitation

• CUREO ® was developed with clinical partners and continuously refined based on their feedback. As a result, it meets the high clinical standards and requirements

• CUREO® is already the most widely used VR therapy system for sensorimotor, cognitive, and perceptive therapy in German clinics.

• In 2024, more than 450,000 therapy sessions were conducted with CUREO ® – and the number continues to rise.

• One key advantage is its use throughout all stages of rehabilitation. This enables low-risk therapy starting from the early rehabilitation phase for immobilized

patients in hospital beds and supports a smooth transition into follow-up care for less impaired individuals.

• With CUREO ® 5, clinics benefi t from simplified therapy planning, flexible group therapy through CUREO ® GROUP+1, and centralized data management in the CUREO® HUB.

• The new intuitive user interface enables faster assignment and control of trainings directly on the screen.

• CUREO® is robust, mobile, and easy to disinfect - ideal for everyday clinical use.

A clinical example

Using our group set-up successfully in a stationary clinic

• With the efficient CUREO® group therapy, up to six patients can be treated simultaneously - now even more flexible with CUREO® GROUP+1, which enables individual therapy within the group system.

• The Training Plan and the Therapy Navigator support therapists in planning and assigning trainings. You can either

• assign the same indication-based Training Plan of up to 60 minutes to all patients, or

• create and play a plan tailored to the individual needs of a single patient. During this time, therapists are

available for patient support, documentation, and organizational tasks.

• The new, even more intuitive user interface provides a quick overview of all active sessions, connection status, and available headsets. Tabs at the top of the screen simplify navigation and show connection status, patient assignment, and training progress.

• For patients, it is clearly visible which training is currently active, and therapists can assign new sessions at the right time.

Therapist’s interface in CUREO® GROUP

1 Tab color in the interface matches the headset color code

2 Patient‘s name

3 Expected duration of the planned training

4 Ongoing patient‘ trainings

5 Remaining time for the current training

“What matters most to us is that you can treat a group, while still addressing each patient individually.”
Klinik

Director

The solution: CUREO ®

CUREO ® for practices

Experiences wth CUREO®

“Thanks to modern methods like CUREO®, we no longer experience staff shortages. Our team is highly motivated and our patients receive excellent therapy.”

• CUREO ® enables parallel therapy, where a therapist can treat one patient conventionally while treating another with CUREO ® at the same time.

• With CUREO ® you can also perform parallel documentation and complete time-consuming tasks during the ongoing therapy session.

• This relieves your staff and enables a higher therapy frequency with consistently high quality, without requiring additional resources.

• Modern digital methods not only increase patient motivation, they also make your practice more attractive for new and existing staff

• CUREO ® creates variety in everyday therapy, boosts motivation , and opens up new, creative therapy possibilities.

A practice example

Two application scenarios from occupational therapy and physiotherapy

Best-practice example: Hand

CUREO® hand therapy with “Blopp“

• The picture below shows a patient training with the “Blopp” finger training program, which is used to train the fine motor skills of the fingertips and hands

• Due to the color coding and increasing complexity, the training can also be considered cognitive training

• In addition to “Blopp,” the module was extended with trainings for individual hand movements and hand combination movements, which can also be combined with electrotherapy.

• For severely impaired patients, there is the hand simulation , which aims to initiate movements through visualization

• The hand module is particularly popular in occupational therapy practices and can be ideally combined with the mirror therapy function.

• Besides “Blopp,” patients can train various other hand and finger functions in CUREO ®, for example picking fruit in the adl kitchen, or performing everyday tasks with the adl cube.

Best-practice example: Shoulder

CUREO® shoulder therapy with „Meteor“

• CUREO ® offers a wide range of VR exercises for targeted rehabilitation of the shoulder.These trainings can be individually adapted in difficulty and movement demands, and they specifically promote mobility, strength, coordination, and body perception.

• In the example shown, the patient is performing the “ Meteor ” training, which activates the entire shoulder girdle through targeted reaching, stretching, and rotational movements. Complex movement sequences train control, reaction speed, and gradually increase movement quality step by step.

• Motivating VR environments help pain patients to overcome movement avoidance and regain confidence in their own movement.

• The modular system allows therapists to tailor shoulder therapy individually and integrate it smoothly into everyday clinical practice.

• Shoulder exercises are frequently used in physiotherapy and are especially suitable for early mobilization and the transition into active training phases.

• In addition to “ Meteor,” many other trainings (such as Taiko, Kite, or Waterball) support shoulder therapy by improving strength, movement radius, and coordination Sonification can also be used as an additional method, providing audible feedback that enhances body perception and promotes controlled, relaxed movement.

CUREO® in detail

CUREO ® is a VR therapy system with 7 modules and more than 50 gamified trainings that support motor, cognitive, and everyday functional goals. It is easy to use, suitable for a wide range of indications, and provides noticeable relief in everyday therapeutic work.

More than 50 gamified trainings in 7 modules

Make the most of the many possibilities with CUREO®

Designed for severely affected patients; strengthens visual perception and supports the treatment of neglect.

Targeted exercises promote upper-extremity mobility and enable motivating motor training.

Supports neuroregulation, stress reduction, and pain relief –suitable for all patients.

The virtual therapy kitchen and training with the adl cube enable everyday tasks with tools and objects.

Trains fine motor skills, mobility, and coordination of hands and fingers.

Promotes color and shape recognition, word finding, spatial perception, coordination, concentration, and memory.

activities

Patients experience small tasks embedded in multisensory virtual environments.

CUREO® in 15 languages

Audio & user interface

• German

• English

• Finnish

• French

• Italian

• Dutch

• Arabic

• Cantonese

• Slovenian

• Spanish

• Czech

• Polish

• Swedish

Audio only

• Turkish

• Ukrainian

Therapy goals, indications, and areas of application

CUREO ® addresses sensorimotor, cognitive, and perceptual impairments. The high-frequency, immersive therapy with multimodal feedback has a positive effect on neuronal processes and contributes to the recovery of motor and cognitive skills as well as the improvement of sensory perception, which leads to improved everyday ability. Increased motivation through gamification, quickly visible training progress, and active relaxation tools contribute to the success of the therapy.

CUREO® was developed for the treatment of the following indications, among others

• Stroke

• Neurodegenerative diseases such as multiple sclerosis, Parkinson‘s disease, ALS

• (Infantile) cerebral palsy (CP)

• Injuries to the spinal cord

• Craniocerebral trauma

• Diseases of the musculoskeletal system

• Pain

• Sarcopenia

CUREO ® can be used in post-operative care to alleviate post-operative complaints e.g. after

• neurosurgical interventions

• orthopedic interventions

• amputations

CUREO ® adresses the following symptoms

• Motor deficits / Paralysis of the upper extremities

• Disorders of proprioception

• Deficits in visual-spatial perception

• Apraxia

• Attention impairments

• Memory impairment

CUREO ® in detail

CUREO ® can improve the quality of life of patients with the following impairments

• Post-traumatic conditions

• Depression

• Effects of prolonged hospitalization

• Stress

• Anxiety

• Pain

• Fatigue

CUREO ® adresses sensorimotor, cognitive, and perceptual impairments

Sensorimotor training

• Sensorimotor function of the upper extremities and trunk

• Extension of the active range of motion

• Fine motor skills of the hand coordination

• Attention

• Memory

• Action planning and execution

• Ability to concentrate

• Spatial perception

• Body perception

• Shape and color perception

• Proprioception

• Reaction time

• Postural control

• Mobilization of the patient through self-initiated movements

Cognition training

• ADL or abilities of daily life

• Therapy adherence

• Problem solving

Perception training

• Visual perception (in visual neglect)

CUREO ®5 sets new standards

CUREO ®5 combines therapeutic effectiveness with high user-friendliness and noticeable relief in everyday work.

CUREO®5

at a glance

New in CUREO®5

Therapy Navigator

Plan effective VR therapy and quickly select suitable trainings.

CUREO® HUB

Digital control center for your therapy: automatic data backup, patient management, and therapy reports.

CUREO® CENTER

Tips, tutorials, and knowledge – always accessible.

Passthrough

Fade out the VR environment to enable eye contact and direct interaction between therapist and patient without removing the headset.

Extended in CUREO®5

CUREO® GROUP+1

Even more flexible: the group system can now also be used in individual mode.

Hand therapy

The best VR hand therapy now includes features for precise gripping and force control — for even more targeted fine motor and coordination training.

Mirror

therapy

One of the most popular features is now even better: mirror therapy is now fully integrated into the Training Plan and available in many modules.

Further Highlights

Updated landscapes and new training variants offer more variety and Turkish is now available in the audio options. Ideal for everyday therapy for all patients.

Therapy Navigator

Your shortcut to targeted exercise

in CUREO®5

Plan your therapy more easily than ever. Select up to three therapy focuses, find precisely matching exercises, and adjust all settings flexibly — before or during the session. From more than 2,000 possible combinations, individual Training Plans and varied single sessions can be created that make therapy faster, more targeted, and more diverse.

Your benefits at a glance

• Easy therapy planning

• Suitable exercises with up to three therapy focuses

• Training Plans created in seconds from over 2,000 possible combinations

• Mirror therapy fully integrate

• More effectiveness and versatility in everyday therapy

„Finally, I can find the right exercises for my patients’ individual therapy goals much faster and plan effective therapy sessions. It makes my everyday work noticeably easier.“
New

The filter | The heart of the Therapy Navigator

Choose from a broad pool of movement patterns and skills based on your patient’s therapy goals. Or filter directly by a specific therapy method such as VR mirror therapy or VR sonification.

The patient view

Suitable training variants for your therapy

Receive an overview of exercises that fi t the therapy focuses you selected. An intuitive suitability score shows how well each training matches your patient and which basic abilities are required.

See at any moment which training your patient is currently performing. This helps you maintain oversight and intervene supportively when needed.

Your individual Training Plan

All selected exercises appear clearly at a glance. Simply adjust the final therapy settings and start the training.

CUREO® HUB

Your smart cockpit for therapy management

New in CUREO®5

Analyze therapy progress with clear reports and visualizations, create and export documentation with just a few clicks. Automatic data synchronization and regular backups ensure that all information stays up to date and securely stored. The CUREO ® HUB meets the highest data protection standards.

Your benefits at a glance

• Manage patients, therapies, and device data centrally

• View all therapy progress clearly and export documentation

• Perform software updates, synchronization, and backups yourself

• Security and data protection according to the highest standards

Manage patients and document progress

All progress, test results, and therapy goals are clearly displayed in one therapy report. Export the report easily as a PDF.

Coming soon

Usage statistics

Keep track of how your systems are being used for example, training duration, total usage, or the utilization of individual devices.

CURE

Monitor devices and keep them ready for use

Monitor your devices and keep them ready for use with just a few clicks. Software updates can be carried out manually to ensure that your CUREO ® systems always function optimally.

The CUREO® CENTER : Discover and access knowledge anytime

Access training materials and knowledge from the CUREO ® CENTER directly via the CUREO ® HUB. Here you will find practical tips, training recommendations, and guides for efficient everyday use of CUREO ®

Try all CUREO® HUB features for free until June 30, 2026. The earlier you start, the more you benefit.

CUREO ® 5 sets new standards

CUREO® CENTER

Faster insights, better therapy

Your digital knowledge center for working with CUREO®

The CUREO ® CENTER supports therapists with practical knowledge, step-bystep instructions, training tips and materials for efficient, effective, and versatile use of CUREO ® in therapy.

This allows you to keep an overview of helpful functions, training modules, and proven methods from everyday therapeutic practice - anytime.

Step-by-step tutorials

Information on hardware, modules, and features

Program recommendations for therapy goals

Practical tips for everyday therapeutic work

Available anytime on PC, smartphone & tablet

Would you like to learn more about the advantages of CUREO®5 for your therapeutic institution?

Further innovations and extensions in CUREO®5

New in CUREO®5

Passthrough

Fade out the VR environment briefl y to enable eye contact and direct interaction between therapist and patient without removing the headset.

Extended in CUREO®5

hand therapy

The best VR hand therapy now includes additional features such as precise gripping and force control. This allows fine motor skills and coordination to be trained even more targeted.

Extended in CUREO®5

O® GROUP+1

• With CUREO ® GROUP+1 you can easily switch between group sessions and individual sessions depending on your needs without interruptions.

• After completing the individual session, the patient can be reintegrated into the group including full data transfer back into group mode.

• Ideal for patients who are not yet mobile enough for group therapy but still want to participate in the therapy.

• This keeps you flexible in planning and increases efficiency throughout the entire therapy operation.

CURE

CUREO® and CUREO® GROUP are based on a simple leasing model. Let our team advise you on which option is best for your therapeutic facility.

Book an appointment

A portfolio tailored to your individual needs

Licence

Benefit from the unbeatable bundle price CUREO®5 GROUP 5-system bundle CUREO®5 GROUP 3-system bundle

Our offer for you

Personal training programs for your success

Your personal onboarding

Advanced training

Your individual in-depth training session with our team. Afterwards, you will be the expert for VR therapy with CUREO®

CUREO® start

Your staff will get to know our service team and the product and receive further information for a fast and successful start with CUREO®!

CUREO® practice phase

Integrate CUREO ® into your daily practice and use the CUREO ® CENTER along with numerous digital learning materials to make your entry into VR therapy as smooth as possible.

Contract signing

After signing, you will receive all key information and access to the CUREO® CENTER in a welcome email.

We are always by your side

• Access to CUREO ® CENTER with extensive learning content

• CUREO ® CONNECT: Weekly online session for your questions and topics

• Support and assistance with updates

• Direct support via phone and email

Our offer for you

Would you like to find out more about the benefits of CUREO® for your therapeutic facility?

Book an appointment with our sales team.

Book an appointment

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