phospho-specific antibodies Phospho-specific antibodies, targeting at protein phosphorylation, are one of the recently well-developed and popularly-searched antibodies. Protein phosphorylation constitutes a key post-translational modification involved in regulation of cell signaling pathways governing a diversity of cellular processes via two mechanisms. One is to generate some new specific protein-binding sites and then lead to the formation of some functional proteins complexes. The other one is to induce conformational changes by phosphorylation at specific residues, which may result in altered enzymatic activity or ion channel permeability. With team of antibody experts working in a state-of-the-art laboratory, Creative Diagnostics provides various monoclonal and specific affinity-purified polyclonal phosphorylation specific antibodies with high sensitivity. All of our advanced instruments and well-developed protocols including peptides design, synthesis, screening strategies and antibody purification together, make it possible to produce a wide variety of phospho-specific antibodies against most phosphoepitope by synthesizing specific phosphopeptides with high purity and low cross reactivity with non-phospho peptide guaranteed.
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