Whitebook CLP

90 years of helping and inspiring people to live a longer and healthier life N°2

Summary

Summary p.8 Interview with Gregor Mattli

p.11 Editorial with Simone Gibertoni

p.13 Our Past

p.19 Our Present

p.39 Clinique La Prairie and Innovation

p.45 The Future of Wellness

p.47 Clinique La Prairie New Dimensions

p.57 Guestbook

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Interview with Gregor Mattli

INTERVIEW WITH GREGOR MATTLI Clinique La Prairie is 90-year old and she has not aged one bit. Moreover, she rejuvenates over the years - a paradox and yet an obvious fact for an institution committed to smoothen the effects of aging. For decades, we have been preserving its flare and liveliness, always driven by an advanced medical research, high-end technological offerings and most importantly, the well-being and satisfaction of our customers.

Family business, team work, consistent and unified vision have strengthened our heritage, are driving our present ambitions and will secure our plans for the future. Today, our efforts to slow down ageing allow us to establish a robust pattern of a healthier life and thus promise a better future to our clients. We continue to move forward while always remembering and preserving our roots and our founders without whom this adventure would not have been possible.

Clinique La Prairie. In 2021, we are taking Professor Niehans' promise and my father's hopes to the next level.

Over time, we have also come to an understanding that efficient Revitalisation program is a sophisticated combination where a peaceful mind and physical health come together with a traditional and alternative medical approach and cutting-edge scientific research. It is with this concept in mind that we create and continue developing our Clinique La Prairie. To Professor Niehans' historical residence with this 19th-century luxurious mansion, we've added an ultra-modern medical center with 50 different specialists and a world-renowned spa containing a range of fifty therapies. It's in these settings, where tradition, modernity and excellence merge, we offer all our passion and expertise to help you forget about time and reverse the clock. In this special year, we also make a promise to you for the near future: to bring us even closer to you, wherever you are in the world.

This anniversary, we dedicate to our founders, the pillars of our big family. Because by relentlessly trying to unravel the body's secrets to lighten the weight of time, we are only following the council and work initiated here, within these walls, 90 years ago, by Professor Paul Niehans, predecessor of the cell therapy. He laid the first stone of this building and brought to life the dream of many - rebirth. When he passed away in the 1970s, it was this legacy and this promise that had to be preserved at all costs. And this became a challenge and a lifetime adventure for my father, Amin Mattli, when he bought this clinic. Since then, generations of doctors and researchers have changed one after the other, striving to improve our rejuvenation techniques, to strengthen the immune system and to preserve longevity. Hence our clinic continuous being a family affair.

Very recently, thanks to the epigenetic test, our research teams succeeded in establishing the exact age of the human body. Revealing this essential knowledge, thanks to the contribution of science, is a giant step forward for us and a crucial point for a personalized approach and a targeted solution for every client. Because we believe that a visible and sustained rejuvenation depends on the inner well-being, we have just launched our own portfolio of food supplements called "Holistic Health". It is a fruit of the several years' research in support of the effects of our cures, thanks to a formula that acts on the fundamentals of a healthy body: immune system, energy, stress and cellular rejuvenation. I am particularly proud of these two offerings that embody and shape the expertise of

With the future openings in Doha and other regions across the Middle East, our inaugurations of sites in Madrid, Shanghai and Bangkok, Clinique La Prairie, so strong thanks to her past, has her eyes more than ever set on the future. Here she is, blowing out her 90 candles and so proud that her reach is beyond the blue of our lake and the tops of our Alps. And 10 years from now, when she is a century old, we will be present and recognized for our mastery in some twenty capitals around the world. We want Clinique La Prairie to become a global player in the high-end healthcare. We want to support you continuously and flawlessly in this race against time, where we will always be one step ahead together.

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Editorial with Simone Gibertoni

Editorial A welcoming address by CEO Simone Gibertoni This 90th milestone is above all a reminder of who we are: pioneers. Clinique La Prairie was the first clinic dedicated to the science of longevity. Today, thanks to our efforts in scientific and medical research, we are still the best in what has become a very competitive universe.

In order to keep our leading position in the field of Health and Wellness, we continue to be grounded in longevity science and improve our programs, always innovating in medical, nutrition, wellness and products. Our lifescience committee is composed of the most expert researchers and clinicians in various fields related to medicine, nutrition, biochemistry, immunology, genetics, pharmacology and, more recently, nutrigenomics.

Inspiring clients to live a "fuller, longer, healthier life" has always been our mission. In Montreux, our experts provide each client with a clear and energizing plan to achieve life-changing results.

We want them to maintain a healthy routine and therefore reap the benefits beyond the clinic’s doors. Long-term results are achieved by using our health and wellbeing technologies and by following the ongoing advice we provide.

Also, now that Clinique La Prairie is expanding internationally, guests will also be able to continue their health journey with us by attending our longevity hubs around the world. After the openings in Madrid and Bangkok, we are looking forward to the upcoming opening of the next one in Doha.

Simone Gibertoni says, "It's obvious that the pandemic has really made our health a priority, making it more important than ever to innovate and push the boundaries of medicine and science. Our clients are looking for highly personalized, evidence-based, preventive journey that combines the health of the body with the wellbeing of the mind. Clinique La Prairie was the first clinic to base its philosophy on longevity, through a unique holistic and genetic approach. It has always been committed to furthering scientific research and innovation for the benefit of living a fuller and longer life. With a 90-year history, our world-class experts are leading the way in understanding how the health and wellness industry will evolve in the years and decades to come."

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Our Past

Our Past Clinique La Prairie is a place of research, shaped by 90 years of evolution, discovery, development and innovation. It is first and foremost a story that began in 1931 with the discovery of cell therapy by Dr Paul Niehans.

La Résidence

Paul Niehans

Paul Niehans is the father of cell therapy and of Clinique La Prairie as we know it today. His passion, humanity and ingenious instinct enabled him to foresee and uncover hitherto undetected mechanisms of regeneration and immunity in organisms, on which he worked to benefit well-being and health.

A grandson of Emperor Frederick III of Germany, Paul Niehans was born on the 21st November 1882 in Berne. After taking courses in philosophy and theology, he went on to study medicine, specifically surgery and endocrinology, at the University of Zurich. Beginning his career as a medical officer, he was stationed on the Lake Geneva Riviera during the First World War, where he worked at the hospitals in Aigle and Vevey, and also at a small private establishment in Montreux, Clinique La Prairie.

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Cary Grant

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Marlène Dielriech

Our Past

Our Past

1930-1940 The 1930s marked the beginning of a story that would span all eras. Dr. Paul Niehans operated in Montreux in a small private establishment, Clinique La Prairie.

Since his early days in medicine, Dr. Niehans had been interested in biological research on the ability of cells to adapt.

satisfaction. Among them were personalities such as Winston Churchill, the German Chancellor and Mariene Dietriech, to name but a few. In 1960, Dr. Niehans published the results of his cell therapy research, breaking new ground in medical science and establishing the pioneering spirit of Clinique La Prairie.

1950-1960

1970-1980

The notoriety of cell treatments is such that the Vatican becomes aware of them. In February 1953, Professor Niehans was called by the doctors of His Holiness to the bedside of the seriously ill Pope Pius XII. The Pope was cured and the news quickly spread around the world. The world media broadcast the information. More and more people heard about Paul Niehans, the effects of his cell therapy and Clinique La Prairie.

In 1971, Doctor Niehans died at the age of 91. Nevertheless, the strength of his convictions lives on and his work and philosophy remain intact. His successors carry on his philosophy of longevity.

People from all over the world sought the attention of the now famous Doctor Niehans. The results achieved never cease to amaze, with patients returning regularly and testifying to their

He developed the clinic and surrounded himself with doctors who were as visionary as he was. His goal was to create a stateof-the-art multidisciplinary facility.

In 1976, Armin Mattli, an accomplished entrepreneur, bought Clinique La Prairie.

The 1980s proved to be a decade of innovation and expansion for Clinique La Prairie.

In 1987, Armin Mattli initiated the development of a medical center of excellence and launched a vast scientific research program on cellular extract, soon to be known as CLP extract.

This research, based on that of Dr. Niehans, culminated, when the CLP extract, purified and honed, was integrated into the Revitalisation program, which renewed its scientific dimension with the objectives of immunity and longevity.

1990-2000 In 1991, Clinique La Prairie's medical center opened, a state-of-the-art facility with operating rooms, consultation offices, radiology and a cosmetic medicine center.

Subsequently, Clinique La Prairie expanded its existing range of services to include specialty consultations, cosmetic surgery, dentistry, dermatology and more. That' s when the clinic adopted its holistic approach. Thanks to this multidisciplinary approach, the clinic is a world leader in its field.

To mark the end of this decade, the Foundation for Research on Aging and Immunology was established in 1998.

The 2000s marked a new turning point in the history of the Clinic. In 2003, the biological effects of the CLP extract were patented by the European Patent Office in Munich. In 2005, a new wellness building was created to further develop the holistic program approach.

The 1600 m2 luxury wellness complex includes 20 beautifully appointed wellness rooms, an indoor pool with a view of the mountains and lake, a steam room, a jacuzzi, a Kneipp course, an ice fountain, sensory showers and floating meditation beds.

In addition, the Clinic develops its prestigious environment with 24 new rooms and suites.

In 2006, the Clinic celebrates its 75th anniversary and its 30th anniversary under the direction of Armin Mattli. Based on the results of continuous scientific research, the new generation of CLP extract is administered orally from 2008.

Theodor Rietschel - Director of Scientific Research has supported the scientific research of the clinic for over 20 years.

La Résidence

Armin Mattli

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Duke and Duchess of Windsor

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Our Past

2010-2021 In 2011, Clinique La Prairie welcomed Gregor Mattli as its head, continuing the Mattli family's involvement with the clinic. In 2016, Simone Gibertoni became CEO of the clinic under the chairmanship of Gregor Mattli. In 2020, Dr. Heini was appointed Medical Director.

In 2016 CLP's longevity method was launched, based on a holistic and preventive approach that targets inflammation, slows aging and boosts immunity using the elements of the ‘four pillars’ philosophy: medical, nutrition, wellbeing and movement. Clinique La Prairie’s method gives guests a unique opportunity to change their cellular environment in a way that will optimize health, strengthen the immune system, benefit the metabolism, support the brain, ultimately building a stronger body and mind.

2018 sees the introduction of the new Master Detox and the Revitalisation Premium programs with the integration of DNA testing, for the first time by a medical Wellness Clinic.

In 2019, the Wellness center welcomes even more technologies such as infratherapy, neurostimulation and deep relaxation techniques, including transcendental meditation, vibrations and sounds. Science is also being pushed even further, with the introduction of the Cellular Genomics supplements with anti-inflammatory, immunostimulant and microbiota-beneficial properties. These products, derived from CLP scientific research, have a direct impact on the process of cellular senescence.

With the opening of the "Aesthetics & Longevity" Center in Madrid, the "Aesthetics and Medical Spa" in Bangkok and an office in Shanghai, the future of La Prairie will involve international expansion.

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Our Present

Our Present Clinique La Prairie is celebrating its 90th anniversary. Like no other, it has been able to maintain and affirm its position as a world leader in the field of medicine, longevity and well-being. It stands out for its ability to reinvent itself, always in keeping with its philosophy of "living fuller and longer". Thanks to ongoing scientific research, Clinique La Prairie is still considered a benchmark in preventive medicine and longevity.

Highly appreciated by a global clientele from 80 different countries, Clinique La Prairie offers holistic health and wellness programs, using the latest technologies and concepts with personalized, preventive programs: For example the flagship Revitalisation program is designed to promote vitality, strengthen the immune system and slow the aging process and the Master Detox program offers the ultimate in customized purification programs.

Clinique La Prairie's health and wellness philosophy combines its expertise and holistic approach based on its four pillars of medical, wellness, nutrition and movement.

The medical team comprises some 50 specialists. Equipped with the latest technology, the clinic offers the most advanced medical and wellness care in a sophisticated environment.

Guests stay in one of the 38 rooms and suites with breathtaking views of the Alps. The award-winning spa is a true oasis of beauty.

Cutting-edge science and traditional practices are combined to provide exceptional experiences focused on results, relaxation and well-being.

In 2021, epigenetic testing makes its debut as well as pioneering nutritional supplements, the Holistic Health range.

The continued dedication to regenerative medicine means Clinique La Prairie is constantly spearheading new formulas to support wellbeing. The Revitalisation programme is strengthened in 2021 by offering an even stronger balance of science, nature and technology to help guests feel their absolute best and live fuller.

© Carlo Mari

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Our Present

90 YEARS OF REVITALISATION 90 years of expertise, care and development, 90 years that have made Clinique La Prairie famous for its exclusive Revitalisation program.

This highly reputed program provides support for a noticeable rejuvenating effect and the slowing of the aging process, cell renewal, resistance to oxidative stress, strengthening of the immune system, and improvement of physical fitness and brainpower.

The principle of Revitalisation is constantly evolving, thanks to the research carried out for many years by a multidisciplinary team of scientists under the aegis of the scientific committee.

The program includes DNA testing, comprehensive health assessments and innovative new treatments in each of the Clinic's four pillars: Medical, Wellness, Nutrition and Movement.

To pay tribute to 90 years of expertise, Clinique La Prairie also wanted to strengthen the science behind its signature program. And, provide a ultimate experience of well-being, immunity and rejuvenation.

Two new formulas to perfect Revitalisation Developed by Clinique La Prairie's team of medical specialists, two activators have been added to this program: a high-performance cellular active ingredient and a treatment based on genomics: - Composed of an organic plant-based mixture and produced in the Montreux laboratories, the "HP-Cellular Active" is a complex to be taken daily during the stay. Thanks to an extraction process developed by the clinic, it contains a fundamental active ingredient that helps improve the oxygen supply to cells.

In addition, it helps regulate oxidative stress and stimulates cells' ability to protect themselves.

- The new protocol "CLP Cellular Genomic FFS1-5" is composed of five vegan supplements that interact with the genes involved in cell stimulation. Carefully developed to link the five priority areas of regeneration (immune system, neuromodulation, anti-inflammation, microbiota recovery and sleep-wake rhythm), this supplement is to be started during the stay. It is then to be used at home for four weeks to complete the effects of the program.

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Our Present

A new tailor-made nutritional approach Clients will also discover a new nutritional approach carefully designed to promote anti-inflammatory health.

To target specific needs and encourage healthy habits, expert dietitians provide clients with tailored nutritional counseling, using a three-phase intervention process: neutralization, rebalancing and personal empowerment.

Wellness Techniques The Revitalisation program also offers vitamin and antioxidant infusions, DNA testing and the wellness techniques of light therapy and neural stimulation to nourish the mind-body connection and reduce stress.

Workouts, revitalizing massages and an anti-aging facial at Clinique La Prairie's award-winning spa are also incorporated, so clients experience deeper, more stable rejuvenating effects.

In just six days, the Revitalisation Program creates the ultimate cellular renewal and gradually restores the body's regenerative power.

Simone Gibertoni, CEO of Clinique La Prairie, says "Clinique La Prairie has spent the last 90 years trying to unlock the secrets of longevity and well-being. This commitment has resulted in the creation of cutting-edge programs to regenerate the body, strengthen the immune system and improve physical and mental performance.

It is with this same commitment to research that the Revitalisation program was redesigned. »

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Our Present

CLINIQUE LA PRAIRIE'S HEALTH PROGRAMS Driven by its renowned holistic approach, Clinique La Prairie has developed programs created by experts in preventive medicine. Each program, combines medical assessments with personalized nutritional, wellness and health plans.

All programs offer a personalized approach, and are carried out over a period of five or six nights, with the exception of the Weight Loss System, which can be spread over 13 days.

PREMIUM REVITALISATION Experience state-of-the-art rejuvenation and health check-ups thanks to the science of the future. Using the world's most advanced cellular regeneration, DNA testing and holistic medicine technologies, this extremely powerful program strengthens and re-energizes you to enhance your life. Its supportive effects on vitality and internal defenses are extended to the vital systems and organs that play an essential role in slowing the aging process: circadian rhythm and brain, digestive system, cardiovascular and immune system.

MASTER DETOX Master Detox is the most advanced detoxification program thanks to DNA test and nutrigenomics. It combines the power of genetics with a personalized nutritional approach. The goal of this program is to eliminate toxins and purify the body in depth in order to regain unparalleled balance and vitality through an anti-inflammatory diet and a nutraceutical cure targeting cellular detoxification. In addition to antioxidant therapy, infratherapy and cryotherapy sessions, and a hot and cold contrast therapy : the program also offers a combination of massages, scrubs and wellness treatments designed to complement the detoxification process.

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Our Present

THE MASTER DETOX

Renowned as the world’s most premium and bespoke cleansing program, is the first detox programme to use genetics to detect deficiencies in the body, the treatment remains unrivalled, with the addition of advanced testing an extended anti-inflammatory diet and a nutraceutical cure targeting cellular detoxification.

The enhanced approach focuses on a Cellular Genomic Detox method that naturally helps the cleansing and purification process. The cure, developed exclusively at the clinic at its life science division, starts during the programme in Montreux and is recommended over the 8 weeks following the stay.

It consists of a set of daily natural supplements that work on activating cellular factors that boost the body’s ability of detoxifying and the microbiota.

Genetic and metal testing, as well as health and dental screenings allow consultants to advise on priorities for each guest’s bespoke detoxification and rebalancing plan.

As part of the revolutionary approach, guests also enjoy an expertly crafted nutritional plan comprising a liquid fast of homemade juices, - 28 -

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and a detox menu of largely vegan dishes to clean the digestive system and tackle nutritional deficiencies and rebalance the body. Dietetic workshops are given to highlight the benefits of prebiotics and healthy ingredients that focus on antiinflammation and immuno-stimulation, with precious guidance to take home to transform guest’s lifestyle towards healthier living.

HydraFacial, cryotherapy, heat therapy, and the signature Clinique La Prairie detox massage are just some of the treatments that boost the holistic elements of the program.

Along with the fitness sessions, which include aerial yoga and personal training, the treatments have the ability to eliminate toxins, decrease fatigue and stress, promote deep cleansing and stimulate the metabolism.

The journey to reset the body and increase vitality continues outside of Clinique La Prairie. Guests are encouraged to adapt the skills learnt during the seven-day retreat into their everyday lifestyle as they unlock the secret of living.

Our Present

ENERGIZING WELLNESS Our holistic health experts help you find ways to rejuvenate and adopt a healthier lifestyle. By taking this precious time for yourself, energy levels are boosted, allowing you to leave feeling calm and refreshed. Making wellness and body balance a priority will result in long-term benefits.

IMMUNITY BOOST This is about giving your immune system the boost it needs to build your body's defenses and overcome the fatigue and stress of daily life.

With the help of health and wellness experts, this program is the perfect choice for boosting your immunity and recharging your batteries, while enjoying time entirely devoted to wellness.

BETTER SLEEP The Better Sleep program aims to identify and treat sleep disorders that impact well-being, such as lack of concentration or memory loss.

This treatment combines several medical examinations to establish a personalized program according to your needs. The approach integrates the different factors that influence sleep quality: diet, health, physical activity, emotions and stress.

WEIGHT LOSS SYSTEM The Weight Loss System program is designed to restore fitness and stabilize metabolism for lasting results. Clinique La Prairie's expertise in wellness, based on decades of research, will transform your eating habits into a healthy lifestyle for fast, optimal and most importantly, sustainable results. This program offers a multidisciplinary approach with the help of a nutritionist, personal trainer, psychologist and wellness therapists.

MEDICAL CHECK-UP The medical check-up integrates a comprehensive assessment of the patient's health with in-depth medical tests and sophisticated analyses. ©Carlo Mari

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Our Present

CLINIQUE LA PRAIRIE'S BEAUTY SURGERY PROGRAMS BEAUTY STEM CELLS The Beauty Stem Cells program is probably the ultimate anti-aging beauty treatment.

Your own stem cells, are reinjected to revitalize your face and give it a youthful boost.

Clinique La Prairie collaborates with the Swiss Stem Cell Foundation, to offer cell storage for 30 years.

CELL BOOST The Cell Boost program is designed to preserve the skin's youthfulness through the power of one' s own cells. This two-day retreat begins with a complete skin analysis and continues with facial rejuvenation using an innovative technique of aesthetic and regenerative medicine. The hydration provided by the Cell Boost treatment gives the face a lasting glow.

© Carlo Mari

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Our Present

UNLOCK LUXURY AND WELLBEING Clinique La Prairie is the only establishment to combine a health and wellness center, a five-star palace and an internationally renowned private clinic.

Clinique La Prairie offers 38 rooms and suites overlooking the sumptuous landscape of the Alps and Lake Geneva.

The Medical SPA International Awards • “Best Destination Spa” on a Global level and “Best Health & Wellness Spa” in Switzerland at Haute Grandeur global awards in 2021 • “Best Luxury Medical Spa” at the World Luxury Spa Awards 2021 • “The Most Prestigious Spa & Wellness Award” at International and Beauty awards 2021 • “Best Spa Wellness Center” at Clinique in Luxury Wellness Centre 2020 • “Switzerland's Best Wellness Retreat 2020” at World Spa Awards • "Medi-Spa of the Year" in the Destination Deluxe Awards 2019 • “Best Spa Innovation” by Conde Nast traveller 2018 • “Best Luxury Spa” International Award of Excellence 2018.

With over 1,600 m2 of space, Clinique La Prairie invites you to a unique multi-sensory experience for your well-being. Swiss Perfection cosmetics, used for treatments at Clinique La Prairie, allow the skin to regenerate by preventing premature aging thanks to the unrivalled Cellular Active IRISA® technology added to plant extracts meticulously chosen for their efficiency.

This exclusive and award-winning space houses a heated indoor swimming pool, nestled in the heart of a sumptuous setting, as well as various facilities, such as a whirlpool, a traditional sauna and a hammam, a Kneipp course paved with pebbles, a hydrotherapy complex, sensory showers, an ice fountain.

The Fitness/ Health Club There is nothing like the Clinic's fitness center to get back into shape. State-of-the-art sports coaches, a luminous space with a superb view of Lake Geneva, sports programs, personalized follow-up and state-of-the-art facilities: Cardio and Technogym machines equipped with the MyWellness connected application allowing interactive sessions as well as activity and performance monitoring, a functional training area equipped with a Kinesis wall, TRX equipment and Bosu and Swiss balls, and aquatic activities with Aquagym classes...

A vast terrace allows for outdoor training sessions, in addition to outdoor activities such as paddling, Nordic walking, mountain hiking or snowshoeing, depending on your wishes...

Individual or group, the range of courses on offer goes from pilates to stretching, including yoga, aerobics, but also step, yogalates, aerial yoga, pilates, Crossfit and many others.

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Our Present

Present

THE MEDICAL CENTER Clinique La Prairie's medical center has an exceptional range of expertise, including more than 50 medical specialists and 3 operating rooms to meet patients both physical and psychological needs.

Among the different specialties represented are angiology, rheumatology, cardiology, gynecology, neurology, pneumology, radiology with an imaging center equipped with the latest technologies, such as 3 Tesla MRI scanners, CT scanners, low dose mammography with 3D tomosynthesis.

SPECIALIZED MEDICAL CONSULTATIONS Internal medicine, cardiology, genetic mapping, dermatology, diabetology, endocrinology, gastroenterology, gynecology, neurology, nutrition, ENT, orthopedics, pneumology, psychiatry, rheumatology, urology, etc.

SURGERY General, orthopedic, gynecological, reconstructive and neurosurgery.

cervico-facial,

aesthetic,

SPECIALIZED CENTERS Aesthetic Medicine Center, Medical Imaging Institute, Sleep Center and Dental Center.

CENTER FOR AESTHETIC MEDICINE Clinique La Prairie's Center for Aesthetic Medicine is dedicated to the well-being of patients and offers innovative solutions, techniques and technologies. Its approach is based on many years of expertise in the constantly evolving field of preventive and restorative aesthetic medicine. A wide range of personalized treatments with long-lasting and effective results are on offer.

Lasers (photo rejuvenation, vascular laser, ablative lasers, laser hair removal), injections (mesotherapy, body mesotherapy, plateletrich plasma (PRP), hyaluronic acid, neuro-relaxants/botulic protein), CoolSculpting, tensor threads, peels, focused ultrasound.

The aesthetic treatments provided at the clinic are innovative, regenerative and non-invasive.

With its many years of expertise in the field of preventive aesthetic medicine, the treatments offered are custom-made and perfectly designed for long-lasting and highly effective results.

DNA ANALYSIS GENETIC TESTING Since 2018, DNA testing has become a key pillar of the Clinic's programs, allowing us to build a comprehensive health map for each - 36 -

individual and tailor a life change program to meet very specific needs.

DNA testing is included in the following programs: Revitalisation, Revitalisation Premium, Master Detox and Weight Loss System. Revitalisation's "Better Aging" DNA test provides a comprehensive overview of hereditary risk factors and allows therapies and nutritional and lifestyle counseling to be tailored to genetic predisposition factors.

The Master Detox and Weight Loss System's DNA testing includes a nutritional analysis to adapt dietary habits.

For detoxification, it indicates the body's ability to absorb and eliminate nutrients, allowing specialists to target specific cleansing pathways.

A comprehensive genetic and nutritional analysis allows for personalized nutritional advice to maintain and improve each individual's health. It can be combined with more traditional laboratory analyses in order to follow the evolution of different parameters.

EPIGENETIC TESTS Our daily choices affect the behavior of our genes, in particular their activation or not. These processes are closely linked to well-being, aging and disease. It is now possible to measure how lifestyle shapes your biological age with a revolutionary epigenetic test.

Thanks to the new science of epigenetics, the medical world is able to offer increasingly personalized medical care. While everyone is born with an unalterable genetic code, epigenetic factors such as lifestyle and environment influence how genes are expressed.

Programs, designed to influence gene expression and reduce biological age, will become a key innovation over the next decade.

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Cinique La Prairie and Innovation

Clinique La Prairie and Innovation

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Cinique La Prairie and Innovation

Cinique La Prairie and Innovation

AT THE FOREFRONT OF SCIENCE

As science evolves and technological advances transform health care, Clinique La Prairie continually embraces innovation, reinforcing its position as a leader in preventive medicine and holistic wellness, as well as in the biosciences.

is able to offer increasingly personalized medical insights.

Since 2021, Clinique La Prairie has been offering epigenetic testing. While everyone is born with an unalterable genetic code, epigenetic factors such as lifestyle and environment influence how genes are expressed.

1. Stem Cells for facial aesthetics In 2019, Clinique La Prairie launched the Beauty stem cells program, designed to beautify, restore and protect the skin using our adipose stem cells derived from our own fat.

Epigenetic assessment allows for reversible and positive gene modification, optimizing nutrition, sleep, and exercise to meet the unique needs of each patient. In the future, experts will most likely be able to adjust genetic profiles in order to prevent diseases resulting from genetic predisposition.

The use of stem cells in beauty helps replace degenerative cells by renewing natural collagen and stimulating tissue regeneration.

3. Nutrigenomic innovation What we eat influences our genes, and so Clinique La Prairie has created exclusive products derived from nutrigenomics, the science that studies the interactions between nutrients and the genes responsible for metabolic balance.

The protocol comprises four phases: extraction, purification, storage and reinjection of stem cells at the end of the treatment.

The benefits are a reduction in the visible signs of aging as well as healthy skin, inside and out.

These CLP Cellular Genomic supplementations begin during the signature programs at the clinic and then continue for two months at home.

Research shows that these stem cells have the power to repair and rejuvenate all tissues while renewing themselves at the cellular level.

Result of the clinic’s lifescience research and lab, they are made up of proven plants with anti-inflammatory, immunostimulant properties, and act directly on the process of cellular senescence.

2. The Epigenetic Revolution Thanks to the new science of epigenetics, the medical world

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SCIENTIFIC COMMITTEE

For over 20 years, Professor Ernst Rietschel has headed Clinique La Prairie's Scientific Committee, in collaboration with internationally recognized experts*. Today, the Scientific Advisory Board is made up of researchers, clinicians and advisors who are among the best in their respective fields: neuroscience, genetics, longevity, biostatistics, nutrigenomics, bioscience and immunology.

Among other partnerships, Clinique La Prairie is collaborating with the Biopôle de Lausanne to continue to step up its research and development in the fields of life sciences, nutritional science and disease prevention.

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Prof. Rietschel: director of scientific research Dr Cohen Armand: longevity Prof Draganski Bogdan: neuroscience Dr. Folli Silvio: cellular genomics and longevity Dr. Gonseth Nussle Semira: epigenetics and preventive medicine Mr. Nussle Sebastien: Epigenetics and Biostatistics Prof. Pichard Claude: Nutritionist Mrs. Tanackovic Goranka: genetics *

Cinique La Prairie and Innovation

LONGEVITY SUPPLEMENTS HOLISTIC HEALTH Clinique La Prairie has added a new dimension to its holistic approach with the launch of Holistic Health, a collection of Swiss-made supplements.

Based on an exclusive Holistic Complex that targets the foundations of well-being, Holistic Health is the most sophisticated supplement offering to date. And for the first time, it allows people to benefit from Clinique La Prairie's cutting-edge medical expertise outside the clinic.

The line targets the five fundamental pillars of wellness with five compounds: neuromics, synerithin, fixentin, immucell and niehanyl. The four products in the line, Age Defy, Balance, Energy and Purity, were created by a team of life science experts. They address stress management, immunity, cellular longevity, rejuvenation and anti-inflammation. These exclusively vegan supplements are all combined with carefully selected micronutrients and plant extracts.

AGE DEFY The first line of defence. Combining two supplements, Regeneressence and Immunity, the routine addresses cell regeneration, anti-inflammation and antioxidant protection to support a long and healthy life. The morning IMMUNITY blend incorporates high-performance antioxidants, actives and vitamins with the patented compounds Cavacurmin® and BetaVia™ to support natural defences.

The evening REGENERESSENCE formula features a powerful combination of eight essential vitamins, antioxidants, and the breakthrough patented FruitFlow® to contribute to cellular protection and stimulation.

BALANCE In today's fast-paced society, balance is essential to achieving daily well-being and reducing stress levels. This program combines 17 essential vitamins, minerals and bioavailable forms of superfoods in ESSENTIAL WELLBEING morning supplement with sleep and relaxation ingredients in REST & RESET evening supplement. The patented ingredient Bluenesse®, known to boost mental clarity and improve responsiveness to stress, is a key ingredient in the relaxing formula.

ENERGY This 3rd supplement stands for FOCUS & PERFORMANCE as it provides a source of brain and body energy with bioactive ingredients known to boost cognitive function and help optimize performance. Enriched with, among other things, specifically - 42 -

stimulating extracts, B vitamins and the patented nootropic CogniviaTM for proven effectiveness, this supplement strengthens memory, reduces fatigue and promotes a feeling of endurance.

PURITY The PURITY supplement participates in the natural cleansing and toxin removal processes of the liver and helps protect against oxidative stress. The formula contains innovative ingredients that are the richest sources of plant antioxidants and vitamins, such as aronia berry extract, camu camu and Chlorella microalgae. This detox product was designed by Clinique La Prairie as the perfect ally for an intense detoxification at home. This two-month formula is recommended three times a year.

Simone Gibertoni CEO, says, "People who attend a program at our clinic can benefit from state-of-the-art products and integrated nutrigenomics throughout the week. Today, we are thrilled to bring our innovative science to many people's daily routines. Our supplements are the result of years of innovation and research to understand how we can support those who lead increasingly intense lives." cliniquelaprairie-hh.com

The Future of Wellness

The future of wellness

Clinique La Prairie's report on the Future of Wellness Clinique La Prairie has always been committed to being at the forefront of scientific research and innovation for the benefit of our health. Its experts are leading the way in understanding how the health and wellness world will shape up in the years and decades to come.

It's the desire to continually evolve and improve that makes Clinique La Prairie the key reference among clinics specializing in longevity. Whatever the field, the future comes down to one crucial point: innovation. In order to look into the future of wellness, Clinique La Prairie interviewed expert practitioners in the various health and wellness fields.

As Simone Gibertoni states, "Obviously, the pandemic has made us more aware of our health, which is pushing the boundaries of medicine and science more than ever. Consumers are looking for highly personalized, meaningful and preventive healthcare that takes a strong holistic approach."

Explore the complete report :

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New Dimensions

Clinique La Prairie's New Dimensions

© Carlo Mari

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New Dimensions

New Dimensions

AESTHETICS AND MEDICAL SPA IN BANGKOK It is in the heart of Asia that the Clinic opened in January 2021 this medical-wellness center at the St Regis Bangkok which offers longevity, nutrition and aesthetic medicine.

The 1,500-square-meter Medi-spa features 16 treatment rooms.

Hammam, Thai massage room, couples suites, massage therapy rooms, and that's not all: relaxation facilities are spread over two floors, including a rain shower area, vitality pools, and a foot reflexology water wall. A true haven of peace that transports patients into a deep sense of fulfillment. This new wellness and longevity center offers an approach focused on anti-aging as well as detoxifying and regeneraring treatments.

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For those who wish to enjoy a wide range of health benefits, the exclusive center provides private consultations, innovative treatments, personal training and exclusive access to the wellness facilities. Longevity, nutrition, aesthetic medicine: the consultations offered cover all the cutting-edge fields that have made and still make Clinique La Prairie's reputation across the globe.

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New Dimensions

New Dimensions

IN MADRID, HOLISTIC BEAUTY & LONGEVITY A new era is expanding with Clinique La Prairie Aesthetics & Longevity.

Echoing the holistic philosophy of Montreux, Madrid now hosts numerous experts, who provide longevity consultations, nutritional coaching and advanced anti-aging aesthetic treatments.

A 600-square-meter space dedicated entirely to the well-being of customers, allowing them to enjoy a unique experience and benefit from Clinique la Prairie's exclusive protocols for improving their lifestyle and perfecting their beauty.

Each visit is customized with carefully selected and interconnected treatments that aim to bring out the beauty in each individual for exclusive results.

"Madrid is a concrete expression of our ambition to expand our expertise abroad, where our customers live," says Simone Gibertoni.

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Guestbook

Clinique La Prairie's Guestbook 2020-2021 Clinique La Prairie had the pleasure of welcoming many celebrities over the years.

The discreet and refined setting of the place guarantees an exclusive experience.

The ideal place to offer our clients a break of health and well-being.

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Guestbook

Guestbook

"Difficult to find the words... If paradise does exist: it is here!

The care, the people, the meals, the doctors. The kindness, the professionalism. Thank you for everything!"

"Thank you for everything. " Bertrand Blier

"Thank you for this wonderful interlude, we are leaving as if brand new". Best wishes to the whole team."

"Thank you for this timeless stay.

One should come every month!"

Carla Bruni

Doria Tillier

Marthe Keller

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Guestbook

Guestbook

"Thank you for a wonderful stay, it was a dream! The care, the setting, the welcome, the delicious food, a treat!

Everything was wonderful! "

“Best Spa in the world! And the best staff. Thank you so much for a magical stay and experience!”

Carly Steel

Irene Jacob

“To the La Prairie Team, I had a great healthy week. The food, the staff, the rooms and the quality of service were absolutely fantastic. We look forward to coming back soon and will definitely be recommending the Clinique to friends and family”

"To all the team, thank you for this dream day."

Keren Ann

Ola Farahat

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Guestbook

Guestbook

“To the wonderful people at Clinique La Prairie, Thank you! For hosting us and showing us such a beautiful stay. Each of you has been lovely and accommodating.

Naomie & I thoroughly enjoyed meeting you and are already looking forward to our nest visit with you.”

Naomie Harris & Bethany Levy

As someone who is obsessed with discovering ways of getting to the very peak of physical health (biohacking). I was in my element at Clinique La Prairie… The mountains and clean air for mental health. What to eat and why/ what not to eat/ infra red sauna / Cryo/ Holistic therapies/ lymphatic drainage massage… all the good stuff.

“We really enjoyed everything.

From the massages, treatments, hospitality, to the people, and their professionalism. After this week of new experiences, we felt rested, rejuvenated, and completely replenished.”

Nicole & Barbara Kimpel

Ellie Goulding

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