Rifagut Tablets (Generic Rifaximin Tablets)

Rifagut Tablets (Generic Rifaximin Tablets)

Rifagut (Generic Rifaximin Tablets) is indicated for the treatment of travelers’ diarrhea (TD) caused by noninvasive strains of Escherichia coli in adults and pediatric patients 12 years of age and older. Rifagut should not be used in patients with diarrhea complicated by fever or blood in the stool or diarrhea due to pathogens other than Escherichia coli.

Rifagut is indicated for reduction in risk of overt hepatic encephalopathy (HE) recurrence in adults.

Rifagut is indicated for the treatment of irritable bowel syndrome with diarrhea (IBS-D) in adults.

To reduce the development of drug-resistant bacteria and maintain the effectiveness of Rifaximin Tablets and other antibacterial drugs, Rifaximin when used to treat infection should be used only to treat or prevent infections that are proven or strongly suspected to be caused by susceptible bacteria.

Rifagut Tablets (Generic Rifaximin Tablets)

Active Ingredient

The active ingredient present in Rifagut tablets is Rifaximin. Each film coated Rifagut tablet contains 200 mg, 400 mg or 550 mg of Rifaximin.

Chemical Structure

The structure of Rifaximin is given below:

Rifagut Tablets are manufactured by Sun Pharmaceutical Industries Limited, India in the strengths of 200 mg, 400 mg and 550 mg. ( Website: https://sunpharma.com/ )

URL: https://www.clearskypharmacy.biz/generic-xifaxan-rifagut-by-sun-pharma.html

Rifagut Tablets (Generic Rifaximin Tablets)

Rifaximin Tablets – Brand Names

Rifaximin tablets are available under various drug trade names that include Rcifax from Lupin, Refatime from Solitaire (Prominent), Rfx from Olcare, Ciboz from Zydus Cadila, Rifagut from Sun Pharmaceutical Industries, Riflect from Sun Pharmaceutical Industries, Rifastop from Mankind Pharma, Rixmin from Cipla, Torfix from Torrent Pharmaceuticals, Sibofix from Dr. Reddy's.

Rifagut Tablets (Generic Rifaximin Tablets)

Uses of Rifagut Tablets

Rifagut (Generic Rifaximin Tablets) is used to treat traveler's diarrhea that is caused by a bacteria called Escherichia coli. It is also used to prevent hepatic encephalopathy, which is a condition that occurs when your liver does not work normally. This medicine is also efficacious in relieving chronic functional symptoms of bloating and flatulence that are common in irritable bowel syndrome (IBS), especially IBS-D. Rifaximin is an antibiotic that works by killing the bacteria and preventing its growth.Rifaximin is highly effective at preventing and treating traveler's diarrhea, with few side effects and low risk of developing antibiotic resistance.

Travelers’ Diarrhea Not Caused by E. coli: Generic Rifaximin was not effective in diarrhea complicated by fever and/or blood in the stool or diarrhea due to pathogens other than E. coli. If diarrhea symptoms get worse or persist for more than 24 to 48 hours, discontinue Generic Rifaximin (Rifagut Tablets) and consider alternative antibiotics. However, this medicine will not work for colds, flu, or other virus infections.

Rifagut Tablets (Generic Rifaximin Tablets)

Rifagut Tablets Dosage

The dosage of Rifagut tablets (Rifaximin Tablets) is given below:

Travelers’ Diarrhea: The recommended dose of Rifagut Tablets (Generic Rifaximin tablets) is one 200 mg tablet taken orally three times a day for 3 days. Rifagut tablets can be administered orally, with or without food.

Hepatic Encephalopathy: The recommended dose of Generic Rifaximin is one 550 mg tablet taken orally two times a day, with or without food.

URL: https://www.clearskypharmacy.biz/generic-xifaxan-rifagut-by-sun-pharma.html

Contraindications

Rifagut tablets are contraindicated in patients with a hypersensitivity to Rifaximin, Rifamycin antimicrobial agents, or any other component of this medication.

URL: https://www.clearskypharmacy.biz/generic-xifaxan-rifagut-by-sun-pharma.html

Rifagut Tablets (Generic Rifaximin Tablets)

Storage Instructions

Rifagut Tablets (Generic Rifaximin Tablets) have to be stored at controlled room temperature i.e. from 20°C to 25°C (68°F to 77°F) with excursions permitted between 15° to 30°C (59° to 86°F).

Keep this as well as all other medicines away from children and pets.

URL: https://www.clearskypharmacy.biz/generic-xifaxan-rifagut-by-sun-pharma.html

Warnings

Travelers’ Diarrhea Not Caused by E. coli: Rifagut Tablets (Rifaximin tablets) was not effective in diarrhea complicated by fever and/or blood in the stool or diarrhea due to pathogens other than E. coli. If diarrhea symptoms get worse or persist for more than 24 to 48 hours, discontinue Rifagut and consider alternative antibiotics.

Clostridium difficile-Associated Diarrhea: Evaluate if diarrhea occurs after therapy or does not improve or worsens during therapy.

Hepatic Impairment: Use with caution in patients with severe (ChildPugh Class C) hepatic impairment.

Concomitant P-glycoprotein (P-gp) inhibitors (e.g., cyclosporine): Caution should be exercised when concomitant use of Rifagut and a P-glycoprotein inhibitor is needed.

URL: https://www.clearskypharmacy.biz/generic-xifaxan-rifagut-by-sun-pharma.html

Rifagut Tablets (Generic Rifaximin Tablets)

Side Effects

Side effects of Rifaximin Tablets (Rifagut tablets) occurring in 5% or more of Patients Receiving Rifagut tablets and at a higher incidence than placebo are Edema peripheral, Nausea, Dizziness, Fatigue, Ascites, Muscle spasms, Pruritus ,Abdominal pain, Abdominal distension, Anemia, Cough, Depression, Insomnia, Nasopharyngitis, Abdominal pain upper, Arthralgia, Back pain, Constipation, Dyspnea , Pyrexia and Rash.

URL: https://www.clearskypharmacy.biz/generic-xifaxan-rifagut-by-sun-pharma.html

Side Effects

The following side effects, have also been reported in the placebo-controlled clinical trial with an incidence rate greater than 2% but less than 5% of patients taking Rifaximin 550 mg taken orally two times a day for hepatic encephalopathy.

Ear and Labyrinth Disorders: Vertigo

Gastrointestinal Disorders:

Abdominal pain lower, abdominal tenderness, dry mouth, esophageal variceal bleed, stomach discomfort

General Disorders and Administration Site Conditions:

Chest pain, generalized edema, influenza like illness, pain not otherwise specified

Infections and Infestations:

Cellulitis, pneumonia, rhinitis, upper respiratory tract infection not otherwise specified

Injury, Poisoning and Procedural Complications:

Contusion, fall, procedural pain

URL: https://www.clearskypharmacy.biz/generic-xifaxan-rifagut-by-sun-pharma.html

Rifagut Tablets (Generic Rifaximin Tablets)

Side Effects

The following side effects, have also been reported in the placebo-controlled clinical trial with an incidence rate greater than 2% but less than 5% of patients taking Rifaximin 550 mg taken orally two times a day for hepatic encephalopathy.

Investigations:

Weight increased

Metabolic and Nutritional Disorders:

Anorexia, dehydration, hyperglycemia, hyperkalemia, hypoglycemia, hyponatremia

Musculoskeletal, Connective Tissue, and Bone Disorders:

Myalgia, pain in extremity

Nervous System Disorders:

Amnesia, disturbance in attention, hypoathesia, memory impairment, tremor

Psychiatric Disorders:

Confusional state

Respiratory, Thoracic, and Mediastinal Disorders:

Epistaxis

Vascular Disorders:

Hypotension

Overdose

No specific information is available on the treatment of overdosage with Rifaximin (Rifagut Tablets). During clinical studies at doses higher than the recommended dose (greater than 600 mg per day for TD, greater than 1100 mg per day for HE or greater than 1650 mg per day for IBS-D), adverse reactions were similar in subjects who received doses higher than the recommended dose and placebo.

URL: https://www.clearskypharmacy.biz/generic-xifaxan-rifagut-by-sun-pharma.html

Overdose

In the case of overdosage, discontinue Generic Rifaximin (Rifagut Tablets), treat symptomatically, and institute supportive measures as required.

URL: https://www.clearskypharmacy.biz/generic-xifaxan-rifagut-by-sun-pharma.html

Rifagut Tablets (Generic Rifaximin Tablets)

Rifagut Tablets During Pregnancy

Rifaximin (Rifagut tablets) is classified by the US FDA as Pregnancy

Category C.

There are no adequate and well controlled studies conducted in pregnant women. Rifaximin has been shown to be teratogenic in rats and rabbits at doses that caused maternal toxicity. Rifaximin tablets (Rifagut tablets) should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus.

It is not known at present if Rifaximin is excreted in human milk. Because many medicines are excreted in human milk and because of the potential for adverse reactions in nursing infants from Generic Rifaximin, a decision should be made whether to discontinue nursing or to discontinue the drug, taking into account the importance of the medicine to the mother.

URL: https://www.clearskypharmacy.biz/generic-xifaxan-rifagut-by-sun-pharma.html

Rifagut Tablets (Generic Rifaximin Tablets)

For more details on Rifagut Tablets click here

Rifagut (Rifaximin Tablets) by Sun Pharmaceutical Industries Limited, India.

URL: https://www.clearskypharmacy.biz/generic-xifaxan-rifagut-by-sun-pharma.html