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Clayco_Life Sciences

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LIFE SCIENCES QUALIFICATIONS

INTEGRATED DEVELOPMENT, DESIGN, ENGINEERING & CONSTRUCTION SERVICES 2026

Designing & Building Environments That Enable Breakthrough Sciences


A MESSAGE TO OUR CLIENTS

Every Day Matters.

So Does Every Decision.

Speed to market is not a competitive advantage. It is a moral imperative. Clayco’s delivery model runs engineering, construction, and validation in parallel — compressing timelines and reducing cost risk in ways the industry has not seen before. Patients are waiting. Let us build faster, together.

SCAN OR CLICK TO WATCH A MESSAGE FROM OUR LEADERSHIP TEAM


DESIGN, ENGINEERING AND CONSTRUCTION

Life Sciences Leadership Team

Leveraging our combined experience in process engineering and operations, cGMP manufacturing, laboratory design, and workplace at various scales – our Enterprise team effectively integrates user requirements and regulatory knowledge into each buildout.

Life Sciences Service Offerings + Site Master Planning & Due Diligence Ryan Abbott PRESIDENT, SOUTHWEST REGION

Jose Rivera

John Lagodney

Charles Heffernan

SR. VICE PRESIDENT

SR. VICE PRESIDENT, DESIGN & ENGINEERING

SR. VICE PRESIDENT, DESIGN & ENGINEERING

+ Strategic Facility Planning & Front-End Loading (FEL) + Regulatory, Compliance & Life Safety Consulting

Edwin Paoli

Marc Hanson

Julie Stupp

Bert Cordova

VICE PRESIDENT, PROCESS ARCHITECTURE

VICE PRESIDENT

VICE PRESIDENT

DIRECTOR OF QUALITY

Shawn Dziedzic

Charlie Dunn

Robert Sunukjian

David Bouffard

VICE PRESIDENT, OPERATIONS

SR. PROJECT DIRECTOR

PROJECT DEVELOPMENT DIRECTOR, LIFE SCIENCES

VICE PRESIDENT MECHANICAL ENGINEERING, LIFE SCIENCES

+ Process Architecture & Manufacturing Design

+ Preconstruction, Budgeting & Project Controls + Design-Build, EPC & Construction Management + Cleanroom Construction & Process Equipment Installation

+ Process, Utility & Facility Engineering

+ Integrated Commissioning, Qualification & Validation (CQV)

+ Laboratory, Cleanroom & Workplace Design

+ Startup, Operational Readiness & Facility Expansions

+ Equipment Procurement & Vendor Management


OUR COMMITMENT TO

Our Clients & Community

PEOPLE & SAFETY

Safety is foundational to our work, and we are all responsible for creating a safe environment. Through regular trainings and awareness activities we prioritize proactive measures. Addressing physical and psychological well-being is vital, and we foster open dialogue for all employees.

82% below national average recordable rate

80% of all projects had zero recordables in 2025

OSHA VOLUNTARY PROTECTION PROGRAM (VPP) STAR 10-YEAR MEMBER

CLAYCO RISING (CULTURE, EMPOWERMENT, AND INCLUSION) Clayco coordinates social impact efforts through Clayco Rising, a leading CEI program in the industry. With 25 years of experience, Clayco Rising creates opportunities and structural change for employees, our trade partners, and communities.

OUR COMMUNITY

Clayco’s culture extends beyond building structures. We’re committed to long-term partnerships with our communities. A vital part of our identity is dedicating time, energy, and resources to projects and nonprofit organizations in the communities where we live and work.

Clayco consciously meets the needs of today, while empowering future generations. As builders and designers, we are the responsible stewards of the built environment and believe it is our duty to protect and preserve the natural and cultural resources of the communities we serve.

OUR ENVIRONMENT

Clayco prioritizes environmental responsibility, as we meet the needs of employees, clients, and future generations. We design and construct buildings to reduce emissions and enhance energy efficiency. We lead with innovative solutions to minimize embodied carbon and waste. We have 100+ Sustainably Certified Projects and 70+ Sustainability Accredited Professionals.

SBTi Net-Zero Approved

AIA 2030 NetZero Committed AIA Materials Pledge


42 YEARS OF THE

4,000 A FIRM OF THE BEST & BRIGHTEST WITH

+

EMPLOYEES ACROSS THE COUNTRY

0.46

A SAFETY LEADER WITH A CURRENT EMR OF

(1.0 INDUSTRY AVERAGE)

A LOOK AT

Who We Are

$8.1B ACCOMPLISHED 2025 REVENUE

Our team specializes in the “art and science of building,” providing fast-track, efficient solutions. Year after year, we are ranked by Engineering News Record as a top 5 design-builder and contractor. By embracing the passion, creativity, and ideas of our people, we have been recognized as the Fast Company Best Workplace for Innovators and Brands That Matter.


IN-HOUSE SERVICES

The Power of Integration

Clayco is an unmatched, collaborative team. Financial planners, designers, engineers, programmers, builders, and clients work transparently, sharing knowledge with a common desire to exceed owner expectations. Our vast offering of in-house disciplines allows us to provide the specialized services to meet our client’s individual project needs to deliver unparalleled results.

Develop

Design & Engineering

+ Site Selection

+ Architecture

+ Development

Build + Design-Build

+ Interiors

+ Process & Manufacturing

+ Financing

+ Urban Planning & Design

+ Building Systems

+ Integrated Delivery

+ Asset Management

+ Landscape Architecture

+ Structural

+ CM@Risk

+ Sustainability

+ VDC/BIM

+ EPC

+ Design-Assist

+ Self-Perform Concrete Construction

+ Self-Perform Mechanical, Electrical & Process Systems

+ Self-Perform Building Envelope

+ Procurement Direct Manufacturer Sourcing Nationwide Purchasing Power Delivery Logistics


Clayco Safe: Outstanding Results

PROACTIVE SAFETY:

A SAFETY CULTURE DRIVEN BY PEOPLE

Everyone Owns Safety, Every Day

80%

OF ALL PROJECTS HAD ZERO RECORDABLES IN 2025

SAFE WORKFORCE + ON-SITE CARE

ONGOING TRAINING

ON-SITE NURSES

PEER OBSERVATIONS

WELLNESS CHECKS

SAFETY AUDITS

STRETCH & FLEX

91%

OF PROJECTS WITH NO LOST TIME IN 2025

0.46

OSHA VOLUNTARY PROTECTION PROGRAM (VPP) MEMBER SINCE 2017

VPP ACROSS 15 STATES + MOBILE WORKFORCE

CURRENT EMR (WELL BELOW 1.0 INDUSTRY AVERAGE)

ENTERPRISE HOURS & RATES total recordable injury rate

88%

total work hours

308% 2017

29.4M Hours

2.64 TRIR

7.2M Hours

2018

2019

0.29 TRIR 2020

2021

2022

2023

2024

2025

2026


Project Life Cycle

Clayco’s iEPCV Model allows for earlier turnover of the facility and ultimately faster delivery of therapies to patients.

= Direct Project Engagement

= Project Support

TRADITIONAL CONSTRUCTION

CLAYCO DIFFERENCE ADVANCED WORK PACKAGING

DETAILED DESIGN & PRECONSTRUCTION

LEVEL OF EFFORT

FEL 1-3 ICQ & VERIFICATION (ASTME2500)

START Clayco Integrated Services Architecture/ Engineering Preconstruction & Construction Concrete Construction Mech., Elect., Process Systems Building Envelope

Procurement

TIME

TRADITIONAL COMMISSIONING & QUALIFICATION

END


Team Experience

Markets We Serve + Life Sciences + Biopharmaceutical + R&D Laboratories + API Pharmaceutical + Institutional + Commercial + Industrial OFFICE LOCATIONS


LIFE SCIENCES—BIOTECH

Long Lead Market Outlook

MARKET SIGNALS BEHIND THE BOTTLENECK

Planning range in weeks. Dot shows average. Red line marks a 52-week critical path threshold.

52 WK 0

PACKAGE

26

78

104

AVERAGE

LARGE SS BIOREACTORS (10,000L+)

80 WK

HIGH-SPEED VIAL FILLING LINES

80 WK

PRE-FILLED SYRINGE FILLING LINES

80 WK

LARGE SCALE PRODUCTION LYOPHILIZERS

80 WK

CARTRIDGE FILLING LINES

66 WK

AMPOULE FILLING LINES

65 WK

INTEGRATED ASEPTIC FILLING ISOLATORS

62 WK

AUTOMATED LYO LOADING / UNLOADING

62 WK

MID-SCALE SS BIOREACTORS (500-5,000L)

58 WK

DISTRIBUTED CONTROL SYSTEMS (DCS)

58 WK

01 GLP-1 CAPACITY RACE

GLP-1 demand and manufacturing expansions keep aseptic fill, PFS, cartridge, and device capacity tight.

02 ANNEX 1 STERILE BASELINE

Contamination-control strategy, RABS / isolators and sterile utility expectations are expanding project scope.

03 POWER GEAR IS SHARED RISK Grid, data center, and manufacturing projects are drawing on the same transformers, switchgear, and controls.

04 U.S. BIOPHARMA CAPEX WAVE

Mega-site announcements add demand for stainless fabrication, automation, commissioning, and validation talent.

SCAN OR CLICK TO VIEW THE CLAYCO COST INDEX REPORT

Updated quarterly, the Clayco Cost Index tracks material costs, labor rates, supply chain conditions, and regional market trends to support accurate budgeting, scheduling, and risk mitigation.


OUR CAPABILITIES

Life Sciences Focus

Aseptic Fill/Finish

Lyophilization

Oral Solid Dosage/Nutraceutical

Syringes

Medical Device

Animal Health

API & Peptides

Cell & Gene Therapy

Oligonucleotides

Packaging

Therapeutic Proteins / ADC

Radiopharmaceutical


Life Sciences Ongoing Work

55%

67%

MANUFACTURING ASRS

DESIGN-BUILD

45%

CENTRAL UTILITIES BUILDING

33%

LAB/ADMIN

ASRS

OTHER

CENTRAL UTILITIES BUILDING

MANUFACTURING/LAB ADMIN

MANUFACTURING/LAB ADMIN

$1.7B

IN ACTIVE LIFE SCIENCES PROJECTS

9

ACTIVE LIFE SCIENCES PROJECTS

2

ASRS

ACTIVE MEGA CAMPUSES

10

ACTIVE OR COMPLETED ASRS FACILITIES

20

+ DEDICATED CENTRAL UTILITIES BUILDINGS


PROJECT EXPERIENCE LIFE SCIENCES

REPEAT CLIENT

Lilly Lebanon Plant 1 (API) Program Lebanon, IN 395,000 SF

6 ACTIVE LILLY PROJECTS ACROSS 2 MEGA CAMPUSES

Image provided courtesy of Eli Lilly

Lilly Medicine Foundry Lebanon, IN 200,000 SF


Confidential Client Sterilization Facility 90,000 SF

Confidential Agar Plate Production Facility St. Louis, MO 16,000 SF

Benson Hill Biosystems Laboratory Creve Coeur, MO 160,000 SF

Confidential Antibody Drug Conjugate Manufacturing Facility St. Louis, MO 110,000 SF


REPEAT CLIENT

5 COMPLETED PFIZER PROJECTS

Pfizer Research & Development Facility Renovation Chesterfield, MO 50,000 SF

Regeneron B18 Logistics Center – TTCX Tarrytown, NY 137,000 SF

Pfizer Covid 19 Pilot Plant Chesterfield, MO 295,000 SF

Pfizer Boulder Campus Phase 1 Building Renovation Boulder, CO 20,000 SF


PROJECT EXPERIENCE SUPPORT FACILITIES

Express Scripts Tech & Innovation Berkeley, MO 240,000 SF

Express Scripts North Huntingdon Front End Pharmacy North Huntingdon, PA 70,000 SF

Bausch & Lomb Pharmaceutical Warehouse Woodruff, SC 432,000 SF

Express Scripts Operations Center Berkeley, MO 226,000 SF


A LANDMARK COMMITMENT

$10M

TO ADVANCE RVCL RESEARCH

01

PROMISING THERAPY

02

PRE-CLINICAL SAFETY

03

FUTURE CLINICAL TRIAL

Targets the malformed TREX1 protein

The next essential step forward

A path toward treatments and a cure

INVESTING IN HOPE Retinal Vasculopathy with Cerebral Leukoencephalopathy (RVCL) is a rare, devasting genetic disease with no cure. For families living with it, every scientific discovery brings the possibility of a different future. The Clayco Foundation is supporting research at the University of Pennsylvania Perelman School of Medicine to advance a promising smallmolecule degrader therapy.

“ What once felt impossible is beginning to feel within reach. ”

Bob Clark, Chairman & Founder, Clayco


Automated Distribution & Cold Storage

Clayco brings broad expertise in warehouse automation, integrated systems, and cold storage solutions, delivering high-performance facilities that support the specialized manufacturing, storage, and distribution requirements of the Life Sciences market.

AMAZON ASRS

SCHNUCKS MARKET COLD STORAGE 1M SF

KOHL’S FULFILLMENT CENTER 936,000 SF

KEY AUTOMATION CONSIDERATION Loads/Foundation Design Structural Reinforcing Floor Flatness/Levelness

THE CUBES AT MESA 1.7MSF

Electrical Loads and Diversity

CHEWY.COM PET FOOD DISTRIBUTION FACILITY 795,000 SF

Backup Power Generation Slab on Grade Tolerance Low Voltage / Controls Integration

DOLLAR GENERAL COLD STORAGE FACILITY 1.1M SF

$16B+

DISTRIBUTION/ WAREHOUSE PROJECT VALUE

70+

COLD STORAGE PROJECTS

KRAFT-HEINZ COLD & DRY STORAGE 650,000 SF

10

ASRS FACILITIES

177

INTEGRATED LJC + CLAYCO DISTRIBUTION/ WAREHOUSEPROJECTS


The Clayco+Client Experience

––– We listen and bring solutions. ––– We anticipate challenges and deliver integrated solutions aligned with your values. ––– We prioritize the continuous safety of our teams—on the project and at home. ––– We seek to understand your concerns so we can provide meaningful support. ––– We do what we say.

––– We partner with you to achieve your project objectives. ––– We communicate openly and mitigate risk proactively. ––– We help your team find the best solutions. ––– Your success is our success. ––– We want you to enjoy working with the Clayco team.

Clayco Core Values Adaptability Grit Sense of Urgency Creativity Courage Results Leadership Mentorship Teamwork


we see BEYOND THESE WALLS to a better TOMORROW

CONTACT US Jose Rivera Senior Vice President Clayco e riverajo@claycorp.com p 512.406.1815

CLAYCORP.COM

John Lagodney Senior Vice President LJC Design & Engineering e lagodneyj@theljc.com p 484.250.2861

Charles Heffernan Senior Vice President LJC Design & Engineering e heffernanc@theljc.com p 484.266.9163

Marc Hanson Vice President Clayco e hansonm@claycorp.com p 531.444.7183

CLAYCORP.COM


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