Pathways LIVE: Authors in Conversation with Tobias Bertsch

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This episode of Pathways LIVE: Authors in Conversation is made possible, in part, by the generous support of our 2025-2026 Partners.

Additional Reading and Videos:

JWC International Consensus Document Lipedema: A paradigm shift and consensus

Link: https://issuu.com/canadianlymphedemaframework/docs/jwc consensus lipoedema

The Debate Around this Fat Disorder Colin Mockery (YouTube)

Although not an HCP presented the scientific facts very clearly and highlighted the difference between the ILA and the USA Standard of Care. The video has already received over 60,000 views.

Link: https://youtu.be/zY37XqfIckg?si=Woi-T3ZK8j8RKu2b

Link: https://theila.net/

The International Lipoedema Association (ILA) website

Numerous myths are explained with short videos you can find the related image here. The ILA is currently running a campaign on the topic of misinformation.

Scientific References

Is the differential diagnosis of lipedema possible by high ultrasoundography possible?

T. Hirsch1; J. Schleinitz2; M. Marshall3; G. Faerber4

https://www thieme-connect de/products/ejournals/pdf/10 12687/phleb2431-4-2018 pdf?

articleLanguage=en

“It has not been possible to detect fluid retention in patients with painful lipohypertrophy.”

Non-contrast MR Lymphography of lipedema of the lower extremities

4 4 5

Michaela Cellina , Daniele Gibelli , Massimo Soresina ,Andrea Menozzi , Carlo Martinenghi , Marta Panzeri , Giancarlo Oliva

https://pubmed ncbi nlm nih gov/32561380

“The fat tissue was homogeneous, without any signs of oedema in pure lipedema patients.”

Indocyanine green lymphography as novel tool to assess lymphatics in patients with lipedema

Giacomo Buso , Lucie Favre , Mario Maufus , Marcella Honorati , Claudia Lessert , Michèle Depairon , Wassim Raffoul , DidierTomson , Lucia Mazzolai

https://pubmed.ncbi.nlm.nih.gov/34896377/#full-view-affiliation-1

“Overall, no major anatomical lymphatic changes were found.“

Differentiation of lipoedema from bilateral lower limb lymphoedema by imaging assessment of indocyanine green lymphography

Helen Mackie , Belinda MThompson , Hiroo Suami ,Asha Heydon-White , Robbie Blackwell , Fiona Tisdall Blake , LouiseAKoelmeyer

https://pubmed ncbi nlm nih gov/36814359/

“Women with lipoedema had normal lymphatic morphology on examination with indocyanine green lymphography.“

Non-contrast MR Lymphography of lipedema of the lower extremities

Michaela Cellina , Daniele Gibelli , Massimo Soresina ,Andrea Menozzi , Carlo Martinenghi , Marta Panzeri , Giancarlo Oliva

d a

https://www.sciencedirect.com/author/26532520200/daniele-maria-gibelli

“The fat tissue was homogenous, without any signs of edema in pure lipoedema patients.”

Increased levels of VEGF-C and macrophage infiltration in lipedema patients without changes in lymphatic vascular morphology

Gunther Felmerer ,Aikaterini Stylianaki , Maija Hollmén , Philipp Ströbel ,Adam Stepniewski ,Anna Wang , Florian S Frueh , Bong-Sung Kim , Pietro Giovanoli , Nicole Lindenblatt , Epameinondas Gousopoulos

https://pubmed ncbi nlm nih gov/32616854/

“No apparent lymphatic anomaly underlies lipoedema, providing evidence for the different disease nature in comparison to lymphoedema.“

Scientific References (Continued)

A Comparative Analysis to Dissect the Histological and Molecular Differences among Lipedema, Lipohypertrophy and Secondary Lymphedema

Julia vonAtzigen ,Anna Burger , Lisanne Grünherz , Carlotta Barbon , Gunther Felmerer , Pietro Giovanoli , Nicole Lindenblatt , Stefan Wolf , , Epameinondas Gousopoulos

https://pubmed ncbi nlm nih gov/?term=Frueh+FS&cauthor id=32616854

“The absence of lymphatic vascular alterations in lipedema in regard to the number and size of the lymphatic vessels was further confirmed.“

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Pathways LIVE: Authors in Conversation with Tobias Bertsch by Canadian Lymphedema Framework - Issuu