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Medicine Titles Autumn | 2016

contents Anaesthesia, Intensive Care and Pain Manangement

Allergic Diseases

Epidemiology, Public Health and Medical Statistics

Haematology

Medical Imaging

Mental Health, Psychiatry and Clinical Psychology

Neurology and Clinical Neuroscience

Nursing

Obstetrics and Gynaecology, Reproductive Medicine

Pathology and Laboratory Science

Anaesthesia, Intensive Care and Pain Management

Fundamentals of Anaesthesia Fourth edition

Edited by Ted Lin Glenfield Hospital, Leicester

Tim Smith Alexandra Hospital, Redditch

and Colin Pinnock Alexandra Hospital, Redditch

Edited in association with Chris Mowatt Alexandra Hospital, Redditch

November 2016 246 x 189 mm 912pp 909 colour illus. 978-1-107-61238-9 Paperback £84.99

why it will sell • Fourth edition has been updated to reflect changes in FRCA curriculum and advances in practice • Written with needs of trainee anaesthetists in mind and so it is focused on key areas to complement both their clinical work and preparation for exams • Diagrams are deliberately simple to allow easy reproduction during an oral examination or in the operating theatre

Fundamentals of Anaesthesia is the gold standard text for the Primary FRCA, encapsulating the basic principles of modern anaesthesia in one easily accessible volume. Written and edited by experts with extensive FRCA examination experience, this text deliberately blends the expertise of invited authors in an unrivalled consistency of style more akin to that of a single author text. All of the subject matter required to pass the exam is condensed into an easy-to-read format. This fully updated fourth edition includes new guidelines, an improved chapter structure, and a new section on clinical ultrasound. The generous use of summary boxes, bullet points, tables and diagrams creates a text that is clear, concise and easy to navigate. Each section covers one of the four components of the SOE. This is a unique revision aid for the Primary FRCA and an essential companion for all exam candidates.

Contents Preface to the first edition; Preface to the second edition; Preface to the third edition; Preface to the fourth edition; How to use this book; Acknowledgements; List of abbreviations; Part I. Clinical Anaesthesia: 1. Preoperative management; 2. Conduct of anaesthesia; 3. Intraoperative management; 4. Postoperative management; 5. Special patient circumstances; 6. The surgical insult; 7. Regional anaesthesia; 8. Principles of resuscitation; 9. Major trauma; Part II. Physiology: 10. Cellular physiology; 11. Body fluids; 12. Haematology and immunology; 13. Muscle physiology; 14. Cardiac physiology; 15. Physiology of the circulation; 16. Renal physiology; 17. Respiratory physiology; 18. Physiology of the nervous system; 19. Physiology of pain; 20. Gastrointestinal physiology; 21. Metabolism and temperature regulation; 22. Endocrine physiology; 23. Physiology of pregnancy; 24. Fetal and newborn physiology; Part III. Pharmacology: 25. Physical chemistry; 26. Pharmacodynamics; 27. Pharmacokinetics; 28. Mechanisms of drug actions; 29. Anaesthetic gases and vapours; 30. Hypnotics and IV anaesthetic drugs; 31. Analgesic drugs; 32. Neuromuscular blocking agents; 33. Local anaesthetic agents; 34. CNS pharmacology; 35. ANS pharmacology; 36. Cardiovascular pharmacology; 37. Respiratory pharmacology; 38. Endocrine pharmacology; 39. Gastrointestinal pharmacology; 40. Intravenous fluids; 41. Pharmacology of haemostasis; 42. Antimicrobial therapy; 43. Clinical trials and basic statistics; Part IV. Physics and Clinical Measurement: 44. Applied physics; 45. Clinical measurement; 46. Anaesthetic equipment; Index.

Additional Information Level: specialist medical trainees, medical specialists/consultants

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Anaesthesia, Intensive Care and Pain Management August 2016 234 x 156 mm 272pp 68 b/w illus. 60 tables 978-1-316-60893-7 Paperback with Online Resource c. £44.99

Returning to Work in Anaesthesia Back on the Circuit Edited by Emma Plunkett West Midlands Deanery, Birmingham

Emily Johnson West Midlands Deanery, Birmingham

and Anna Pierson Birmingham School of Anaesthesia With the increasing frequency of breaks from practice, the importance of proper preparation and guidance for doctors returning to work has recently been recognised by the Academy of Medical Royal Colleges and the Royal College of Anaesthetists. This is the first dedicated resource to support anaesthetists returning to work after a significant break of any kind, and is designed to complement the growing range of regional and national return to work courses by gathering relevant information and advice into one easily accessible reference source. Divided into three parts, specific to different stages in the return to work process, this book offers information and advice about the practicalities of returning to work, 120 different clinical scenarios to refresh the reader’s knowledge, and a collection of useful guidelines and checklists for the first days and weeks back, forming a vital practical resource for anaesthetists in this situation and those supporting them.

Contents why it will sell • This is the first reference source to gather all relevant and useful information for returning to anaesthesia after a break into one single, easily accessible format, making it useful for doctors at any point in the process • The book is divided into three distinct parts, each with a specific purpose, making it simple and convenient for readers to find the information they need quickly • The knowledge refreshing section includes 120 different clinical scenarios, covering common dilemmas and serious emergencies in a variety of question styles to engage readers and allow them to assess their own knowledge and progress

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Introduction; Part I. The Practicalities of Returning to Work: 1. A break from practice: the current state of play; 2. Return to work guidance; 3. Returning to work experiences; 4. Preparing to return to work: RTW programmes; Good medical practice and revalidation; Statutory and mandatory training; Returning from sick leave; Keeping in touch (KIT) days; Changing to less than full time (LTFT) working; Continuing professional development; 5. Improving your return to work: should I find a mentor?; Using technology to your advantage; Communication and team working; Limitations and sources of help; Avoiding adverse outcomes and what to do if one occurs; Fatigue and burnout; 6. Supporting a colleague’s return to work: supporting a trainee: working with educational supervisors and college tutors; Supporting a consultant’s return to work; Part II. Refreshing Your Knowledge: 7. Scientific principles; 8. Emergency management and resuscitation; 9. Airway management; 10. General principles; 11. Obstetrics; 12. Intensive care medicine; 13. Paediatrics; 14. Pain medicine; 15. Regional anaesthesia; 16. Neuroanaesthesia; 17. General, urological and gynaecological surgery; 18. Day surgery; 19. Trauma and orthopaedics; 20. Subspecialty anaesthesia; 21. Patient safety; 22. Ethical and legal issues; Part III. Guidelines, Updates and Checklists: 23. Pre-operative assessment and anaesthetic planning; 24. Consent and documentation; 25. AAGBI guidelines; 26. WHO Surgical Safety Checklist; 27. Drug doses; 28. Paediatric physiology and equipment; 29. Practical procedures; 30. Resuscitation algorithms; 31. Intensive care guidelines; 32. Analgesic ladders; 33. Difficult Airway Society (DAS) guidelines; 34. National Audit Project (NAP) Summaries; 35. National Institute for Health and Care Excellence (NICE) Guidance. Additional Resources: http://www.cambridge.org/9781316608937 Scratch-off code on inside front cover of book gives user access to online material, companion website features guidelines and checklists for Part III

Additional Information Level: medical specialists/consultants, specialist medical trainees

Allergic Diseases

Impacts of Climate Change on Allergens and Allergic Diseases Edited by Paul J. Beggs Macquarie University, Sydney

August 2016 253 x 177 mm 224pp 31 b/w illus. 978-1-107-04893-5 Hardback £79.99

Climate change has been identified as the biggest global health threat of the twenty-first century. Hundreds of millions of people around the world currently suffer from allergic diseases such as asthma and allergic rhinitis (hay fever), and the prevalence of these diseases is increasing. This book is the first authoritative and comprehensive assessment of the many impacts of climate change on allergens, such as pollen and mould spores, and allergic diseases. The international authorship team of leaders in this field explore the topic to a breadth and depth far beyond any previous work. This book will be of value to anyone with an interest in climate change, environmental allergens, and related allergic diseases. It is written at a level that is accessible for those working in related physical, biological, and health and medical sciences, including researchers, academics, clinicians, and advanced students.

Contents

why it will sell

1. Introduction; 2. Impacts of climate change on aeroallergen production and atmospheric concentration; 3. Impacts of climate change on the distributions of allergenic species; 4. Impacts of climate change on aeroallergen dispersion, transport, and deposition; 5. Impacts of climate change on allergenicity; 6. Impacts of climate change on allergen seasonality; 7. Impacts of climate change on indoor allergens; 8. Interactions among climate change, air pollutants, and aeroallergens; 9. Impacts of climate change on allergic diseases; 10. Synthesis and conclusion.

• An in-depth and comprehensive assessment from which readers will gain a complete picture of the impacts of climate change on allergens and allergic diseases • The topic is approached from a global/ international perspective, and readers will gain a complete picture of the topic rather than that for just one region or nation

Additional Information

• Both past and future impacts of climate change on allergens and allergic diseases are examined, helping readers to understand the impacts that have already happened and that we are currently living with, as well as projections for the future

Level: academic researchers, professionals, graduate students

• Each chapter considers knowledge gaps and research priorities, showing the directions in which research efforts are required in the future

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Epidemiology, Public Health and Medical Statistics November 2016 246 x 189 mm 450pp 88 b/w illus. 66 tables 978-1-107-52915-1 Paperback c. £34.99

Essential Epidemiology An Introduction for Students and Health Professionals Third edition

Penny Webb Queensland Institute of Medical Research

Chris Bain Queensland Institute of Medical Research

and Andrew Page University of Western Sydney Taking a practical approach and supported by global examples from all areas of health, the new edition of this popular and highly commended textbook has been updated to reflect current epidemiological thinking and teaching. Based on feedback from teachers and students, material has been reordered to better suit courses and reflect the underlying logic and purpose of epidemiology. • Provides students with a rounded picture of the field by emphasizing the commonalities across different areas of epidemiology, including clinical epidemiology, and highlighting the key role of epidemiology in public health • Avoids complex mathematics by restricting this to optional material, thereby keeping the book accessible to students from non-quantitative backgrounds • Integrated and supplementary questions help students to reinforce concepts • A wealth of online material is available at www.cambridge.org/essential_ epidemiology, including additional questions, advanced material for key concepts, recommendations for further reading, links to useful websites and slides for teaching, supporting both students and teachers.

why it will sell • Demonstrates the commonalities between different areas of epidemiology and emphasizes the key role of epidemiology in public health • Considers the nature and practical implications of the fundamental biases of selection and measurement, providing a clear conceptual outline, examples, and flow charts to support students as they master this tricky topic • Avoids complex mathematics, making the book accessible to those from a non-quantitative background • Online resources include additional questions, suggestions for further reading, links to useful websites and teaching slides

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Contents Preface; 1. Epidemiology is …; 2. How long is a piece of string? Measuring disease frequency; 3. Who, what, where and when? Descriptive epidemiology; 4. Healthy research: study designs for public health; 5. Why? Linking exposure and disease; 6. Heads or tails: the role of chance; 7. All that glitters is not gold: the problem of error; 8. Muddied waters: the challenge of confounding; 9. Reading between the lines: reading and writing epidemiological papers; 10. Who sank the boat? Association and causation; 11. Assembling the building blocks: reviews and their uses; 12. Surveillance: collecting health-related data for epidemiological intelligence and public health action; 13. Outbreaks, epidemics and clusters; 14. Prevention: better than cure?; 15. Early detection: what benefits at what cost?; 16. Epidemiology and the public’s health; Answers to questions; Appendix 1. Direct standardisation; Appendix 2. Standard populations; Appendix 3. Calculating risk and lifetime risk from routine data; Appendix 4. Indirect standardisation; Appendix 5. Calculating life expectancy from a life table; Appendix 6. Why the odds ratio approximates the relative risk for a rare disease; Appendix 7. Formulae for calculating confidence intervals for common epidemiological measures; Appendix 8. The Mantel–Haenszel method for calculating pooled odds ratios; Glossary; Index. Additional Resources: http://www.cambridge.org/9781107529151 Additional questions, suggestions for further reading, links to useful websites, slides for teaching

Additional Information Courses: Epidemiology, Epidemiology and Public Health Departments: Epidemiology, Public Health, Preventative Medicine, Biosciences Level: graduate students, medical students

Epidemiology, Public Health and Medical Statistics October 2016 247 x 174 mm 352pp 978-0-521-54995-0 Paperback £29.99

Planning Clinical Research Robert A. Parker Harvard Medical School, Massachusetts

and Nancy G. Berman Harbor-UCLA Medical Center Planning a clinical study is much more than determining the basic study design. Who will you be studying? How do you plan to recruit your study subjects? How do you plan to retain them in the study? What data do you plan to collect? How will you obtain this data? How will you minimize bias? All these decisions must be consistent with the ethical considerations of studying people. This book teaches how to choose the best design for your question. Drawing on their many years working in clinical research, Nancy G. Berman and Robert A. Parker guide readers through the essential elements of study planning to help get them started. The authors offer numerous examples to illustrate the key decisions needed, describing what works and what does not work, and why. Written specifically for junior investigators beginning their research careers, this guide will also be useful to senior investigators needing to review specific topics.

why it will sell • Over 200 examples in multiple research areas illustrate different issues in clinical study design, including examples illustrating what does not work • Many of the examples are presented in several parts, illustrating the thought process involved in planning a study • In addition to separate chapters on ethical issues and informed consent, the authors discuss specific ethical issues arising from the activities discussed in each chapter

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Contents Part I. Introduction: 1. Questions before starting on the details; 2. Ethics; 3. Informed consent; Part II. Study Designs: 4. Overview of study designs; 5. Designs for interventional studies; 6. Cohort studies; 7. Case-control studies; 8. Cross-sectional studies; 9. Record reviews; 10. Selecting a design; Part III. Core Concepts Applicable to All Study Designs:11. Generalizability and validity; 12. Study population; 13. Getting and keeping participants; 14. Study data – how variables are used; 15. Study data – endpoints; 16. Predictor and confounding variables; 17. Bias; 18. Avoiding bias; Part IV. Additional Concepts for Interventional Studies: 19. Describing your intervention; 20. Randomization – what and why; 21. Techniques for randomization; 22. Blinding; 23. Techniques needed for blinding intervention studies; 24. Compliance and adherence; Part V. Additional Concepts for Observational Studies: 25. Defining populations for cohort studies; 26. Identifying participants for case-control studies; 27. Matching in nonrandomized studies; 28. Blinding in observational studies; Part VI. Practical Issues: 29. Acquiring high-quality data; 30. Data storage.

Additional Information Level: medical specialists/consultants, specialist medical trainees, academic researchers

Haematology

Hematopoietic Cell Transplants Concepts, Controversies and Future Directions Edited by Hillard M. Lazarus

Reinhold Munker

Case Western Reserve University, Ohio

Louisiana State University, Shreveport

Robert Peter Gale

and Kerry Atkinson

Imperial College London

University of Queensland

Armand Keating

Edited in association with Syed Ali Abutalib

University of Toronto

Andrea Bacigalupo

August 2016 276 x 219 mm 704pp 60 b/w illus. 70 colour illus. 145 tables 978-1-316-60669-8 Hardback with Online Resource £150.00

why it will sell • Adopts an evidence-based approach to topics and problems, allowing readers to separate factual solutions from empiricism • Chapters are uniform in style throughout, providing a consistent and user-friendly resource while also allowing readers to benefit from the authors’ and editors’ wealth of experience • Controversies and challenges are clearly explained, enabling and inspiring readers to contribute to the science and practice of hematopoietic cell transplantation

Midwestern Regional Medical Center, Cancer Treatment Centers of America, Chicago

Ospedale San Martino, Genoa This authoritative new book provides a comprehensive overview of diagnostic and therapeutic strategies in hematopoietic cell transplantation, explaining key concepts, successes, controversies and challenges. The authors and editors discuss current and future strategies for major challenges, such as graft-versushost-disease, including new prophylaxis and treatments. They also discuss long-term complications, such as second malignancies and cardiovascular complications. Chapters are written by leading world experts, carefully edited to achieve a uniform and accessible writing style. Each chapter includes evidence-based explanations and state-of-the-art solutions, providing the reader with practice-changing advice. Full reference lists are also supplied to facilitate further exploration of each topic. Each copy of the printed book is packaged with a password, giving readers online access to all text and images. This inspiring resource demystifies both the basics and subtleties of hematopoietic cell transplantation, and is essential reading for both senior clinicians and trainees.

Contents Dedications; The editors; List of contributors; Preface; A brief history of hematopoietic cell transplantation; Current use and trends in hematopoietic cell transplantation; Biology: critical components of hematopoietic cell transplantation; Part I. Recipient Selection for Hematopoietic Cell Transplantation; Part II. Donor Selection for Allogeneic Hematopoietic Cell Transplants: A Moving Target; Part III. Collecting and Processing of the Graft; Part IV. Early Posttransplant Interval; Part V. Infections after Hematopoietic Cell Transplantation – Progress?; Part VI. Late Complications of Hematopoietic Cell Transplantation; Part VII. Other Complications of Hematopoietic Cell Transplants; Part VIII. Prevention, Detection and Treatment of Relapse after Hematopoietic Cell Transplants; Part IX. Selection of Conditioning Regimen and Challenges with Different Types of T-Cell Depletion Methods; Part X. Hematopoietic Cell Transplants for Acute Leukemia and Myelodysplastic Syndrome; Part XI. Hematopoietic Cell Transplants for Myeloproliferative Neoplasms; Part XII. Hematopoietic Cell Transplants for Lymphomas – Changing Indications; Part XIII. Plasma Cell Dyscrasias: Hematopoietic Cell Transplants; Part XIV. Autotransplants for Solid Neoplasms; Part XV. Hematopoietic Cell Transplants for Non-Neoplastic Diseases; Part XVI. Novel Transplant Strategies; Part XVII. Novel Cell Therapies and Manipulations: Ready for Primetime?; Index.

Additional Information Level: medical specialists/consultants, specialist medical trainees

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Haematology

Robert Wynn | Rukhmi Bhat | Paul Monagle

PEDIATRIC HEMATOLOGY A PRACTICAL GUIDE

Pediatric Hematology A Practical Guide Robert Wynn Central Manchester University Hospitals, Manchester

Rukhmi Bhat Northwestern University Feinberg School of Medicine, Chicago

and Paul Monagle University of Melbourne, Australia

October 2016 246 x 189 mm 303pp 6 b/w illus. 33 colour illus. 96 tables 978-1-107-43936-8 Paperback £59.99

Hematology is often considered a challenging subject by students and junior medical staff alike. Using key scientific and clinical principles, this succinct guide provides a summary of modern day-to-day clinical practice in paediatric hematology. Focusing on the facts that underpin patient management, each chapter offers an initial summary of a particular paediatric hematologic condition. Several key clinical scenarios set out how common difficulties should be managed, from the neonate with line thrombosis, to the newly presenting patient with leukaemia, and the child who has suffered a stroke. Covering all hematology topics on the syllabus of the American Board of Paediatrics subspecialty examinations, this authoritative guide is ideal for both postgraduates and junior doctors, whose understanding of hematological conditions will increase greatly upon reading. This comprehensive and practical book specifically aims to equip clinicians to diagnose and manage children with hematological illness, and to support them and their families.

Contents why it will sell • Succinct chapters provide a quickreference overview of evidencebased guidelines for the more experienced haematologist • Each clinical scenario includes advice on how to manage the patient and, if appropriate, how to communicate with children and their families • Chapters include colour images and flowcharts, and follow a standardised format for ease of reading

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1. Normal hemopoiesis and the physiology of blood; 2. The coagulation system; 3. Common laboratory tests used in hematology and how to interpret them; 4. Reference ranges in children; Clinical scenario 1. The child with newly presenting acute leukemia; 5. Neonatal anemia; 6. Neonatal abnormal myelopoiesis and the hematology of Down syndrome; 7. Neonatal thrombocytopenia; 8. Neonatal bleeding disorders; Clinical scenario 2. Hyperleucocytosis; 9. Neonatal thrombotic disorders; 10. Inherited bone marrow failure syndromes; 11. Acquired bone marrow failure syndromes: aplastic anemia; 12. Sideroblastic anemia; Clinical scenario 3. Management of the child with a mediastinal mass; 13. Iron deficiency; 14. Disorders of vitamin B12 and folate; 15. Hemolytic anemia; 16. Infections in hematology patients and the hematological features of infectious disease; Clinical scenario 4. The approach to the neutropenic child with fever; 17. Sickle cell disease; 18. Thalassemia; 19. Neutropenia; 20. Neutrophil function disorders; Clinical scenario 5. The approach to the child with pancytopenia; 21. Inherited thrombocytopenia; 22. Acquired thrombocytopenia and immune thrombocytopenia purpura (ITP); 23. Immune deficiency; 24. Hemophagocytic Lymphohistiocytosis (HLH) and other non-malignant histiocytic disorders; Clinical scenario 6. Does this child have lymphoma?; 25. Osteopetrosis; 26. Hemophilia; 27. Congential and acquired von Willebrand disease; 28. Rare inherited bleeding disorders; Clinical scenario 7. DiamondBlackfan anemia, transient erythroblastopenia or other cause of red cell aplasia in children; 29. Acquired bleeding disorders; 30. Venous thrombosis in children; 31. Arterial thrombosis in children; 32. Stroke in children; Clinical scenario 8. Approach to evaluation for a bleeding disorder in a child with suspected non-accidental injury (NAI); 33. Anticoagulation in children; 34. Blood transfusion indications and safe use in children; 35. Adverse reactions to blood products and special transfusion circumstances; 36. Acute lymphoblastic leukemia; Clinical scenario 9. The neonate with catheter related thrombosis; 37. Acute myeloid leukemia; 38. Juvenile myelomonocytic leukemia (JMML) and myelodysplastic syndromes (MDS); 39. Principles of blood and marrow transplantation; Clinical scenario 10. Neonatal renal vein thrombosis.

Additional Information

Level: specialist medical trainees, medical specialists/consultants

Medical Imaging

Advanced Neuroradiology Cases Challenge Your Knowledge Edited by Lázaro Luís Faria do Amaral Hospital Beneficência Portuguesa

Asim K. Bag University of Alabama, Birmingham

Fabricio Guimarães Gonçalves University of Brazil

and Prasad B. Hanagandi University of Toronto

October 2016 276 x 219 mm 544pp 881 b/w illus. 14 colour illus. 6 tables 978-1-107-08871-9 Hardback £99.99

why it will sell • Presents a unique and comprehensive collection of the rarest clinical conditions • Highly illustrated with more than 800 clinical images • Encourages a structured decision-making process towards a primary diagnosis

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Featuring atypical cases and focusing on advanced imaging techniques, this book presents a compilation of unusual CNS pathologies with characteristic imaging findings. The aim is to aid the speedy diagnosis of otherwise rarely encountered clinical conditions and improve patient care. Presented as more than 130 real cases with extensive imaging description and step-by-step guidelines on how to diagnose individual pathologies, each scenario is backed by the most up-to-date literature available. The cases include some of the most recently described clinical conditions. The case-based format and description of each clinical journey encourages readers to engage with the diagnostic process and facilitates self-study. This book is for any radiologist who practices neuroradiology, neuroradiology fellows, neuroimaging fellows, practicing neurologist and neurology residents.

Contents Contents; Contents including case titles; List of contributors; Foreword; Foreword; Preface; Acknowledgements; How to use this book; 1. Neurodegenerative diseases: cases 1-20; 2. Neurovascular diseases: cases 21-37; 3. Neuroinfectious diseases: cases 38-50; 4. Neuroinflammatory diseases: cases 5159; 5. Metabolic diseases involving central nervous system: cases 60-82; 6. Central nervous system tumors: cases 83-117; 7. Congenital diseases manifesting in adults: cases 118-137; Index.

Additional Information Level: medical specialists/consultants, specialist medical trainees

Medical Imaging

Interventional Oncology Principles and Practice of Image-Guided Cancer Therapy Second edition

Edited by Jean-Francois H. Geschwind Yale University School of Medicine, Connecticut

and Michael C. Soulen Department of Radiology, University of Pennsylvania Hospital, Philadelphia

September 2016 276 x 219 mm 368pp 204 b/w illus. 94 colour illus. 43 tables 978-1-107-04347-3 Hardback £125.00

Interventional oncology has emerged as an important specialty within cancer care, providing targeted therapy and palliative benefits without the side effects of chemotherapy, surgery and radiation. Covering the principles of current and emerging interventional oncology techniques and detailed diagnosis, staging and treatment algorithms, this book outlines the ways in which these image-guided therapies can inform cancer management strategies. Access to the most current information is vital in this rapidly growing and evolving area of practice. This new edition reflects the most recent clinical data on interventional oncology procedures. Chapters on image guidance and targeting, tumor ablation, embolotherapy, and response assessment have been updated to reflect major technological advances, and new material on microwave ablation and irreversible electroporation has been added. This invaluable resource for interventional radiologists provides essential education and guidance on the full range of minimally invasive image-guided procedures and their integration into comprehensive cancer care.

Contents why it will sell • New and updated chapters reflect the most current clinical data and information on interventional oncology procedures • Features a dedicated section on palliative care, an essential aspect of cancer management • Provides everything the interventional oncologist needs in one volume, without being too specialized or too general

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Part I. Principles of Oncology: 1. Interventional oncology: the fourth pillar of cancer care; Part II. Principles of Image-Guided Therapies: 2. Principles of radiofrequency and microwave tumor ablation; 3. Principles of irreversible electroporation; 4. Principles of high intensity focused ultrasound; 5. Principles of tumor embolotherapy and chemoembolization; 6. Principles of radioembolization; 7. Principles of intraarterial infusional chemotherapy in the treatment of liver metastases from colorectal cancer; 8. Imaging in interventional oncology: role of image guidance; 9. Novel developments in MR assessment of treatment response after locoregional therapy; Part III. Organ-Specific Cancers – Primary Liver Cancers: 10. Assessment and triage of hepatocellular carcinoma; 11. Image guided ablation of hepatocellular carcinoma; 12. Embolization of liver tumors: anatomy; 13. Conventional chemoembolization and chemoembolization with drug-eluting beads: technique and future potential; 14. 90Yttrium radioembolization for hepatocellular carcinoma; 15. Image-guided therapy of intrahepatic cholangiocarcinoma; Part IV. Organ-Specific Cancers – Liver Metastases: 16. Colorectal masses: ablation; 17. Assessment, triage and chemoembolization for colorectal liver metastases; 18. Radioembolization for colorectal liver metastases; 19. Assessment, triage and liver-directed therapies for neuroendocrine tumor metastases; 20. Preoperative portal vein embolization; Part V. Organ-Specific Cancers – Extrahepatic Biliary Cancer: 21. Extrahepatic biliary cancer: stenting, brachytherapy and photodynamic therapy; Part VI. Organ-Specific Cancers – Renal Cell Carcinoma: 22. Management of small renal masses; 23. Embolotherapy in the management of renal cell carcinoma; Part VII. Organ-Specific Cancers – Chest: 24. Image-guided ablation in the thorax; Part VIII. Organ-Specific Cancers – Musculoskeletal: 25. Percutaneous ablation of painful metastases involving bone; 26. Cementoplasty and musculoskeletal interventions; Part IX. Organ-Specific Cancers – Prostate: 27. Prostate ablations; Part X. Specialized Interventional Techniques in Cancer Care: 28. Vascular access: venous and arterial ports; 29. Palliative care and symptom management; 30. CT-guided neurolysis for cancer-related abdominal and pelvic pain; 31. Palliative procedures for ascites and effusion.

Additional Information Level: medical specialists/consultants

Medical Imaging

MRI from Picture to Proton Third edition

Donald McRobbie South Australian Medical Imaging, Adelaide

Elizabeth A. Moore Philips Research Laboratories, The Netherlands

and Martin J. Graves Cambridge University Hospitals, Cambridge

November 2016 246 x 189 mm 400pp 89 b/w illus. 293 colour illus. 22 tables 978-1-107-64323-9 Paperback £59.99

why it will sell • Includes break-out boxes explaining the clinical context • Provides guidance and ideas for imaging experiments to try • Offers sections with advanced content for extending your study • Additional supportive materials are available online

MR is a powerful modality. At its most advanced, it can be used not just to image anatomy and pathology, but to investigate organ function, to probe in vivo chemistry, and even to visualise the brain thinking. However, clinicians, technologists and scientists struggle with the study of the subject. The result is sometimes an obscurity of understanding, or a dilution of scientific truth, resulting in misconceptions. This is why MRI from Picture to Proton has achieved its reputation for practical clarity. MR is introduced as a tool, with coverage starting from the images, equipment and scanning protocols and traced back towards the underlying physics theory. With new content on quantitative MRI, MR safety, multi-band excitation, Dixon imaging, MR elastography and advanced pulse sequences, and with additional supportive materials available on the book’s website, this new edition is completely revised and updated to reflect the best use of modern MR technology.

Contents Glossary; 1. MR: what’s the attraction?; Part A. The Basic Stuff: 2. Early daze: your first week in MR; 3. Seeing is believing: introduction to image contrast; 4. Lost in the pulse sequence jungle?; 5. The devil’s in the detail: pixels, matrices and slices; 6. What you set is what you get: basic image optimisation; 7. Improving your image: how to avoid artefacts; 8. Spaced out: spatial encoding; 9. Getting in tune: resonance and relaxation; 10. Let’s talk technical: MR equipment; 11. Ghosts in the machine: quality control; Part B. The Specialist Stuff: 12. Acronyms anonymous I: spin echo; 13. Acronyms anonymous II: gradient echo; 14. The parallel universe: parallel imaging and novel acquisition techniques; 15. Go with the flow: MR angiography; 16. A heart-to-heart discussion: cardiac MRI; 17. It’s not just squiggles: in vivo spectroscopy; 18. To BOLDly go: fMRI, perfusion and diffusion; 19. Making it count: quantitative MRI; 20. But is it safe? Bio-effects; 21. Where are we going now?; Appendix: maths revision; Index. Additional Resources: http://www.cambridge.org/9781107643239 Additional materials including interactive graphics

Additional Information Level: specialist medical trainees, professionals

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Mental Health, Psychiatry and Clinical Psychology

The Psychoses of Menstruation and Childbearing Ian Brockington University of Birmingham

THE PSYCHOSES OF

Menstruation and Childbearing IAN BROCKINGTON

November 2016 234 x 156 mm 250pp 2 b/w illus. 33 tables 978-1-107-11360-2 Hardback c. £69.99

why it will sell • Provides a complete account of childbearing and menstrual psychoses, based on over 3000 works in many languages • Describes the complexity of the psychoses of childbearing, including many organic and non-organic forms, to aid a better diagnosis and treatment • Presents over twenty distinct forms of psychoses, offering insights for further research

Childbearing, from the standpoint of psychological medicine, is the most complex event in human experience. Of the dozens of disorders that affect the generative process, or are unleashed as complications, many fall under the heading of ‘psychoses’ – profound disturbances of thought, perception, cognition and behaviour. These psychoses disrupt personal and family life at a critical time. Reviewing the wide range of psychoses that complicate the reproductive process, Ian Brockington proposes radical changes to the concepts of postpartum and menstrual psychoses, with suggestions for fresh research initiatives. Armed with this comprehensive knowledge and wielding a raft of interventions, many women can be restored to health and their vital roles in the family and community. When the risk factors are known, multidisciplinary preventive strategies can transform the lives of vulnerable women. This is essential reading for psychiatrists, obstetricians and gynaecologists, midwives, general practitioners, neuroscientists and related professions worldwide.

Contents Foreword; Preface; List of abbreviations; Part I. Introduction: 1. Data; 2. History; Part II. The Organic Psychoses of Pregnancy and the Puerperium: 3. Infective delirium; 4. Eclamptic and Donkin psychoses; 5. Wernicke–Korsakow psychosis; 6. Chorea psychosis; 7. Vascular disorders; 8. Other specific neuropsychiatric disorders; 9. Incidental organic psychoses; Part III. The Psychopathology of Parturition: 10. Introduction; 11. Parturient delirium; 12. Unconscious delivery; 13. Acts of desperation; 14. Other parturient psychoses; 15. Delirium and stupor immediately after the birth; Part IV. Non-Organic Psychoses of Childbearing: 16. The literature; 17. Symptoms; 18. Classification; 19. Clinical forms; 20. Episode onset; 21. The bipolar/cycloid group; 22. Management; 23. Risks; Part V. Menstrual Psychosis: 24. The catamenial process; 25. Medicine and menstruation; 26. Definition and classification; 27. Timing within the menstrual cycle; 28. Timing within the life cycle; 29. Links with the psychoses of childbearing; 30. Investigations; 31. Causes; 32. Management; Part VI. The Challenge and the Opportunity: 33. What is known; 34. Impediments to the growth of knowledge; 35. Research opportunities; Appendix: the Anne Roper interview; Index.

Additional Information Level: medical specialists/consultants, specialist medical trainees

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Mental Health, Psychiatry and Clinical Psychology

Wellbeing, Recovery and Mental Health Edited by Mike Slade King’s College London

Lindsay Oades University of Melbourne

and Aaron Jarden Auckland University of Technology

November 2016 234 x 156 mm 336pp 33 b/w illus. 42 tables 978-1-107-54305-8 Paperback £39.99

why it will sell • Explores the relevance of recovery research to the non-mental health community, making this of interest to a wide range of readers including public health specialists, community development workers, and policy-makers across all areas of government • Applies wellbeing research to mental health services with the expertise of editors and authors who are international leaders in their field • Brings together two bodies of knowledge, merging content that is interdisciplinary and will lead to scientific advances

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This book brings together two bodies of knowledge – wellbeing and recovery. Wellbeing and ‘positive’ approaches are increasingly influencing many areas of society. Recovery in mental illness has a growing empirical evidence base. For the first time, overlaps and cross-fertilisation opportunities between the two bodies of knowledge are identified. International experts present innovations taking place within the mental health system, which include wellbeing-informed new therapies, e-health approaches and peer-led recovery communities. State-of-the-art applications of wellbeing to the wider community are also described, across education, employment, parenting and city planning. This book will be of interest to anyone connected with the mental health system, especially people using and working in services, and clinical and administrators leaders, and those interested in using research from the mental health system in the wider community.

Contents Foreword; 1. Why wellbeing and recovery?; 2. The science of wellbeing and positive psychology; 3. Recovery and mental health; 4. Wellbeing policy: an overview; 5. Positive psychology and severe mental ill-health: strengths-based cognitive-behavioural interventions in psychosis; 6. Conceptual framework for wellbeing in psychosis; 7. Meaning in life and wellbeing; 8. The complete state model of mental health; 9. Collaborative recovery model: from mental health recovery to wellbeing;10. Positive psychotherapy: a wellbeing approach toward recovery; 11. WELLFOCUS PPT for psychosis; 12. Mobile health; 13. Wellbeing and recovery in the emergency services: how do we care for those who care for us?; 14. Recovery learning communities and the road to wellbeing; 15. Recovery colleges and co-production; 16. Wellbeing in nonWestern cultures; 17. Wellbeing policy in Australia and New Zealand; 18. Population level: wellbeing in the general population; 19. Community level: translating wellbeing policy, theory and evidence into practice; 20. Positive education: visible wellbeing and positive functioning in students; 21. Positive tertiary education in a residential setting: Kooloobong Village; 22. Living well in cities: towards a location-based model of perceived urban liveability; 23. Wellbeing enhancing workplaces; 24. Need-supportive parenting and its role in the wellbeing and recovery of individuals: a self-determination theory perspective; 25. Social marketing of wellbeing; 26. Wellbeing and recovery: a possible future.

Additional Information Level: professionals, medical specialists/consultants

Neurology and Clinical Neuroscience August 2016 234 x 156 mm 200pp 43 b/w illus. 63 tables 978-1-107-66390-9 Paperback with Downloadable Video c. £44.99

Dizziness A Practical Approach to Diagnosis and Management Second edition

Adolfo Bronstein Imperial College London

and Thomas Lempert Department of Neurology, Schlosspark Klinik, Berlin Dizzy patients are notoriously difficult to diagnose as doctors require knowledge spanning several subspecialties, including neurology, otolaryngology, internal medicine and psychiatry. This updated second edition integrates the essential information from these fields, providing advice that is both practical and accessible. Beginning with two jargon-free chapters on anatomy, physiology and examination techniques, the book follows a coherent structure organized according to clinical presentations, such as recurrent vertigo, positional vertigo and chronic dizziness. Each chapter is summarized with a table showing diagnoses and their key features, ensuring that the relevant differential diagnoses are readily available. Access to more than sixty online video clips is included, illustrating bedside findings from pathological nystagmus to specific balance problems. With practical advice offered for a range of difficult clinical situations, this comprehensive guide will enable any doctor to feel confident when confronted with dizzy patients.

why it will sell • Offers skills and insights from the everyday work of two world experts

Contents 1. Essential anatomy and functions of the balance system; 2. Symptoms and examination of the patient with vertigo and dizziness; 3. A single episode of prolonged dizziness; 4. Recurrent vertigo and dizziness; 5. Positional vertigo; 6. Chronic dizziness and unsteadiness; 7. Dizziness, imbalance and falls in the elderly; 8. Treatment of the dizzy patient.

• Includes over sixty video clips, and fifteen of these are new to this edition

Additional Resources: http://www.cambridge.org/9781107663909 Video clips

• Provides a new section discussing the evidence base of dizziness treatments

Additional Information

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Level: medical specialists/consultants

Neurology and Clinical Neuroscience

Complications of Neuroendovascular Procedures and Bailout Techniques Edited by Rakesh Khatri

Jean Raymond

Fort Wayne Neurological Center, Indiana

Department of Radiology, Centre Hospitalier de l’Université de Montréal

Gustavo J. Rodriguez Hennepin Stroke Center, Minneapolis

and Adnan I. Qureshi Department of Neurology, University of Minnesota

September 2016 234 x 156 mm 320pp 236 b/w illus. 12 colour illus. 41 tables 978-1-107-03002-2 Hardback £69.99

why it will sell • Practical text with tips and tricks on how to manage intraoperative complications • Extensive illustrations to demonstrate correct procedures and potential pitfalls • Authored by a team of experienced clinicians from various specialties who share the tricks of their trade

Neuroendovascular and neurointerventional therapy is a specialty where disseminating personal knowledge and expert opinion is extremely important, owing to the lack of large-scale clinical trials. The management of complications that occur during or immediately after therapeutic interventions is particularly challenging because these can significantly affect patient outcomes. This book presents how various complication scenarios are handled by well-qualified authorities in the field of neurointervention from three disciplines: neurology, neurosurgery, and neuroradiology. Contributors describe their management of these complications, focusing on the common principles that all the specialists agree on, and give tips and tricks for ‘bailout’ procedures to help get the practitioner out of trouble. The book is well illustrated and covers the full range of neuroendovascular and neurointerventional procedures. The book will appeal to neurointerventionists, neuroradiologists, stroke physicians, neurosurgeons and vascular surgeons for its practical approach to managing these commonly encountered problems.

Contents List of contributors; 1. Groin complications during neuroendovascular procedures; 2. Complications in endovascular embolization of intracranial aneurysms: prevention and bailout techniques; 3. Complications associated with embolization of arteriovenous malformations and fistulas; 4. Complications during intracranial angioplasty and stent placement; 5. Complications during the intra-arterial treatment of ischemic stroke; 6. Carotid angioplasty and stenting: complication avoidance and management; 7. Complications with extracranial stenting other than carotid stenting; 8. Complications during head and neck embolization; 9. Complications during endovascular provocative testing and bilateral inferior petrosal sinus sampling; 10. Role of neurocritical care in prevention and treatment of acute respiratory, cardiovascular, and neurological complications in the angiographic suite; 11. Periprocedural planning for neuroendovascular procedures; 12. Relevant pharmacology for neurovascular procedures; 13. Radiationrelated complications of neuroendovascular procedures; Index.

Additional Information Level: medical specialists/consultants

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Neurology and Clinical Neuroscience

The Behavioral Neurology of Dementia Second edition

Edited by Bruce L. Miller University of California, San Francisco

and Bradley F. Boeve Mayo Clinic, Rochester

October 2016 246 x 189 mm 480pp 39 b/w illus. 34 colour illus. 40 tables 978-1-107-07720-1 Hardback £94.99

why it will sell • Describes the latest research findings in the dementia field – information is up to date and engaging for health care professionals • The number of people affected by dementia is increasing rapidly – this book provides a resource for anyone who sees patients with dementia to aid accurate diagnosis and management • The chapter authors are leaders in their field – the quality of the research and evaluation of the data in this book is unparalleled in that the authors are speaking from firsthand knowledge of the data and patients involved

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This new edition of The Behavioral Neurology of Dementia provides clinicians and researchers with the latest research findings written by the leading dementia experts. With chapters ranging from cognitive evaluation to imaging, and genetics and pathology to treatment, the detailed clinical descriptions of diseases and symptoms serve not only as an educational tool for trainees, but also as an opportunity for experienced clinicians to deepen their knowledge and better serve their patients. After years of little progress, the pace of discovery has been speeding up in the last decade, and the authors distil the most valuable discoveries into clear, insightful chapters with applicable information. All the chapters from the first edition have been refreshed with new text and figures. There are new chapters on autoimmune antibodyassociated encephalopathy; chronic traumatic encephalopathy; and sleep issues in dementia.

Contents Preface; 1. Dementia at the bedside; 2. Neuropsychiatry of dementia; 3. Neuroimaging in dementia; 4. Epidemiology and risk-factors for dementia; 5. Genetic approaches to neurodegenerative disease; 6. Animal models of dementia; 7. Neuropathology of dementia; 8. Alzheimer’s disease; 9. Frontotemporal dementia; 10. Primary progressive aphasia; 11. The non-fluent/agrammatic variant of primary progressive aphasia; 12. Semantic dementia (semantic variant primary progressive aphasia); 13. Logopenic variant of primary progressive aphasia; 14. The cognitive neurology of corticobasal degeneration and progressive supranuclear palsy; 15. Amnestic mild cognitive impairment; 16. Non-amnestic mild cognitive impairment; 17. Early clinical features of the Parkinsonian-related dementias; 18. The Lewy body dementias; 19. Cognitive and behavioral abnormalities of vascular cognitive impairment; 20. CADASIL: a genetic model of arteriolar degeneration, white matter injury, and dementia in later life; 21. Jakob–Creutzfeldt disease and other prion diseases; 22. Autoimmune antibody-associated encephalopathy and dementia syndromes; 23. Chronic traumatic encephalopathy; 24. Treatment of Alzheimer’s disease; 25. Cognitive disorders of the very old; 26. Delirium masquerading as dementia; 27. Sleep issues in dementia; Index.

Additional Information Level: medical specialists/consultants

Nursing

Chronic Care Nursing A Framework for Practice Linda Deravin-Malone Charles Sturt University, Wagga Wagga, New South Wales

and Judith Anderson Charles Sturt University, Bathurst, New South Wales

July 2016 255 x 190 mm 280pp 35 b/w illus. 35 tables 978-1-316-60074-0 Paperback £44.99

why it will sell

Chronic Care Nursing: A Framework for Practice provides a comprehensive and accessible overview of the role of the nurse in dealing with chronic conditions across a variety of healthcare settings in Australia and New Zealand. The first part of the book provides a road map for the implementation of chronic care, by outlining how two essential approaches to chronic care management – the Chronic Care Model and the World Health Organization’s Innovative Care for Chronic Conditions Framework – can help to improve patient outcomes at both national and international levels. The second part devotes separate chapters to key conditions – including dementia, disability, palliative care and mental health – and highlights the pressing contemporary considerations of each condition. Written by an expert author team of clinicians and academics, this book is full of helpful educational tools such as national competencies, case studies and reflective questions, and is an indispensable resource for students and registered nurses.

Contents

• Provides a structured overview of the role of the nurse in dealing with chronic conditions, drawing on the WHO Chronic Care Model and the Innovative Care for Chronic Conditions Framework

Part I. Frameworks for Chronic Care Management: 1. Frameworks for chronic care managements; 2. Implementing the macro level of the ICCCF; 3. Implementing the meso level of the ICCCF; 4. Implementing the micro level of the ICCCF; 5. The Australian and New Zealand health care systems; Part II. Nursing Care of Clients with Chronic Conditions: 6. Cancer control; 7. Chronic cardiovascular conditions; 8. Injury prevention; 9. Depression, anxiety, and substance misuse and abuse; 10. Mental health issues of a psychotic nature; 11. Diabetes mellitus; 12. Chronic respiratory conditions (asthma and COPD); 13. Arthritis and musculoskeletal conditions; 14. Chronic obesity; 15. Dementia care; 16. Chronic kidney disease (CKD); 17. Disability; 18. End of life care; 19. Parkinson’s disease and multiple sclerosis.

• Presents a narrative-style, personcentred approach to chronic care nursing

Additional Information

• Includes case studies, reflection points and discussion questions to help students engage with and comprehend the content

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Courses: Chronic Care Nursing Level: undergraduate students

Obstetrics and Gynaecology, Reproductive Medicine

SECOND EDITION

Best Practice in Labour and Delivery Second edition

Edited by Sir Sabaratnam Arulkumaran St George’s Hospital Medical School, University of London

Best Practice in

Labour and Delivery Edited by Sir Sabaratnam Arulkumaran

October 2016 246 x 189 mm 384pp 100 b/w illus. 16 colour illus. 98 tables 978-1-107-47234-1 Paperback £59.99

why it will sell • Every chapter has been rewritten after reviewing the subject in the latest MBRACCE-UK Report, Cochrane database, RCOG Green-top and other guidelines – completely up to date and authoritative • The book has been mapped on the curriculum and syllabus of the Advanced Training Skills Module on intrapartum care for MRCOG trainees – this makes it an ideal book for O&G specialist trainees and midwives • Several new diagrams and pictures have been added to the chapters in the book, making the text more accessible – easier to understand the topic being discussed

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In light of new recommendations for intrapartum care, this fully updated second edition offers a review of best practice in all aspects of labour and delivery. This authoritative guide incorporates revised recommendations from the latest MBRRACE-UK Report, NICE guidelines, Cochrane Reviews and RCOG Green-top Guidelines to provide advice that is in line with the latest research and practice. New chapters cover the aspects of non-technical skills, ranging from leadership and team work to situational awareness and decision making. This edition also emphasises the problem of adherent placenta and discusses how it should be managed. With its modern, evidence-based approach, Best Practice in Labour and Delivery is the ideal textbook for those training in labour ward practice and studying for postgraduate examinations. Offering clear and practical guidance, this comprehensive book will help all obstetricians, obstetric anaesthetists, midwives and nurse practitioners to understand and deliver the best clinical care to patients.

Contents List of contributors; Preface; Acknowledgements; 1. Pelvic and fetal cranial anatomy and stages and mechanism of labour; 2. The first stage of labour; 3. Analgesia and anaesthesia in labour; 4. Intrapartum fetal monitoring; 5. Uterine contractions; 6. The management of intrapartum ‘fetal distress’; 7. Nutrition and hydration in labour; 8. Prolonged second stage of labour including difficult decision-making on operative vaginal delivery and caesarean section; 9. Instrumental vaginal deliveries: indications, techniques and complications; 10. Caesarean deliveries: indications, techniques and complications; 11. Breech and twin delivery; 12. Cord prolapse and shoulder dystocia; 13. Antepartum haemorrhage; 14. Management of the third stage of labour; 15. Postpartum haemorrhage (PPH); 16. Management of morbidly adherent placenta; 17. Acute illness and maternal collapse in the postpartum period; 18. Episiotomy and obstetric perineal trauma; 19. Induction of labour; 20. Preterm prelabour rupture of membranes (pPROM); 21. The management of preterm labour; 22. Labour in women with medical disorders; 23. Management of women with previous caesarean section; 24. Rupture of the uterus; 25. Management of severe pre-eclampsia/ eclampsia; 26. Neonatal resuscitation and the management of immediate neonatal problems; 27. The immediate puerperium; 28. Triage and prioritization in a busy labour ward; 29. Risk management in intrapartum care; 30. Teamworking, skills and drills on the labour ward; 31. Cerebral palsy arising from events in labour; 32. Objective Structured Assessment of Technical Skills (OSATS) in obstetrics; 33. Nontechnical skills to improve obstetric practice; Index.

Additional Information Level: medical specialists/consultants

Obstetrics and Gynaecology, Reproductive Medicine October 2016 234 x 156 mm 192pp 34 b/w illus. 68 colour illus. 11 tables 978-1-107-48550-1 Paperback c. £39.99

Handbook of CTG Interpretation From Patterns to Physiology Edited by Edwin Chandraharan St George’s University of London This book promotes an evidence-based paradigm of fetal heart rate monitoring during labour, with a move away from the traditional ‘pattern-based’ interpretation to physiology-based interpretation. Chapters are presented in a systematic and accessible format, covering topics such as non-hypoxic causes of fetal brain injury, pre-existing hypoxia, types of intrapartum hypoxia, erroneous monitoring of maternal heart rate, fetal scalp blood sampling and fetal ECG (STAN), intermittent auscultation and medico-legal issues. Sections on ‘pearls’ and ‘pitfalls’ highlight good practice and common errors to promote best practice. End-of-chapter exercises allow the reader to engage with the theory and test their knowledge of key areas. This is a highly practical manual aimed at obstetricians and midwives, particularly those undergoing CTG training. The book will also be very useful to midwifery and medical students and to all those involved in multiprofessional intrapartum care.

why it will sell • Chapters include key messages, key CTG pathophysiology, common pitfalls and CTG exercises to re-enforce knowledge and test readers’ understanding of key areas • Covers medico-legal aspects in detail, enabling the reader to get a better understanding of the medico-legal costs of CTG misinterpretation and how to avoid common errors • Reflects the multidisciplinary nature of intrapartum care, making this manual suitable for a wide audience including midwives, obstetricians and neonatologists who wish to have a greater understanding of CTG

Contents List of contributors; Preface; Acknowledgment; Glossary; 1. ‘An eye opener’: perils of CTG misinterpretation. Lessons from confidential enquiries and medico-legal cases; 2. Physiology of fetal heart rate control and types of intrapartum hypoxia; 3. Fetal oxygenation; 4. Understanding the CTG: technical aspects; 5. Applying fetal physiology to interpret CTG traces: predicting the NEXT change; 6. Avoiding errors: maternal heart rate; 7. Antenatal cardiotocography; 8. Intermittent (intelligent) auscultation in the low risk setting; 9. Current scientific evidence on CTG; 10. Role of uterine contractions and intrapartum re-oxygenation ratio; 11. Intrapartum monitoring of a preterm fetus; 12. Role of chorioamnionitis and infection; 13. Meconium: why is it harmful?; 14. Intrapartum bleeding; 15. Labour with a uterine scar: the role of CTG; 16. Impact of maternal environment on fetal heart rate; 17. Use of CTG with induction and augmentation of labour; 18. Recognition of chronic hypoxia and the preterminal cardiotocograph; 19. Unusual fetal heart rate patterns: sinusoidal and saltatory patterns; 20. Intrauterine resuscitation; 21. Management of prolonged decelerations and bradycardia; 22. ST-Analyser: case examples and pitfalls; 23. Role of a computerised CTG; 24. Peripheral tests of fetal wellbeing; 25. ST-Analyser (STAN): principles and physiology; 26. Operative interventions for fetal compromise; 27. Non hypoxic causes of CTG changes; 28. Neonatal implications of intrapartum fetal hypoxia; 29. Role of the anaesthetist in the management of fetal compromise during labour; 30. Medico-legal issues with CTG; 31. Ensuring competency in intrapartum fetal monitoring: the role of GIMS; 32. Physiology-based CTG training: does it really matter?; Index.

Additional Information Level: specialist medical trainees

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Obstetrics and Gynaecology, Reproductive Medicine

Handbook of Gestational Surrogacy International Clinical Practice and Policy Issues Edited by E. Scott Sills Center for Advanced Genetics, California

September 2016 246 x 189 mm 256pp 14 b/w illus. 9 tables 978-1-107-11222-3 Hardback £64.99

There is an increasing demand for gestational surrogacy in current reproductive medicine practice. Infertile couples often engage overseas surrogates, which increases the risk for legal and ethical complications. This book provides clinical guidance on the provision of gestational surrogacy on a worldwide basis, with brief summaries of the legal position within countries where it is offered. This volume provides a comprehensive overview of surrogacy for clinicians, counsellors, attorneys, legislators and anyone interested in reproductive health policy by filling an immediate niche as a resource for those interested in third-party reproductive treatments.

Contents why it will sell • Adopts an international perspective, highlighting global similarities and differences in clinical practice, with contributors from 25 countries • Tackles topical issues, exploring the challenges and successes of gestational surrogacy from the perspectives of special populations, including single, same-sex, and LGBT parents • Outlines the latest information on national surrogacy legislation, providing contemporary insights into issues and trends that impact treatment in various jurisdictions

1. Surrogacy’s past, present and future; 2. The ideal surrogate: Santa Claus, Easter Bunny or Tooth Fairy?; 3. Gestational surrogacy, ethics and the family; 4. Gestational surrogacy and the feminist perspective; 5. Surrogacy’s changing social profile; 6. Addressing global inequalities in surrogacy; 7. Surrogacy as medical tourism: philosophical issues; 8. LGBT issues in surrogacy: present and future challenges; 9. The emotional work of a ‘labor of love’: an ethnographic account of surrogacy arrangements in the United States; 10. Psychological and interpersonal factors in gestational surrogacy; 11. Saying no to surrogacy: a European view; 12. Gestational surrogacy agreements: enforcement and breach; 13. Routine embryo screening and surrogacy: current challenges and future directions for preimplantation genetic testing; 14. Gestational surrogacy in Argentina; 15. Gestational surrogacy in Australia; 16. Surrogate motherhood in Belgium; 17. Gestational surrogacy in Canada; 18. A baby’s citizenship and kinship ties after surrogate birth: the case in France; 19. Gestational surrogacy in the Republic of Georgia; 20. Crossborder reproductive surrogacy in India; 21. Reproductive surrogacy in Iran; 22. Gestational surrogacy in the Republic of Ireland; 23. Surrogacy in Israel: state-controlled surrogacy as a mechanism of symbolic control; 24. Gestational surrogacy in Japan; 25. Gestational surrogacy in Korea; 26. Gestational surrogacy in the Grand Duchy of Luxembourg; 27. Gestational surrogacy in Malaysia; 28. Reproductive surrogacy in New Zealand; 29. Gestational surrogacy in Nigeria; 30. Gestational surrogacy in Norway; 31. Gestational surrogacy in Portugal and Brazil; 32. Gestational surrogacy in the Russian Federation; 33. Gestational surrogacy practice in Sweden; 34. Gestational surrogacy in Thailand; 35. Gestational surrogacy in Ukraine; 36. Surrogacy in the United Kingdom: present and future challenges; 37. Reproductive surrogacy in the United States of America: trajectories and trends; 38. Gestational surrogacy concerns: the American landscape; 39. Gestational surrogacy in California; 40. Gestational surrogacy in the District of Columbia and Maryland, USA; 41. Surrogacy in Missouri.

Additional Information www.cambridge.org/rights foreignrights@cambridge.org

Level: medical specialists/consultants

Obstetrics and Gynaecology, Reproductive Medicine

The Vulva A Practical Handbook for Clinicians Second edition

Gayle Fischer University of Sydney

and Jennifer Bradford University of Western Sydney

Foreword by Lynette Margesson

September 2016 234 x 156 mm 144pp 39 colour illus. 3 tables 978-1-316-50895-4 Paperback £44.99

why it will sell • A new insight into vulval disease written by a dermatologist and a gynaecologist in close clinical and research partnership for the last twenty years – presents a combined, integrated approach, rather than from a single specialty perspective

This practical handbook reviews the important, but complex, area of vulval disease and will help busy clinicians help their patients. The authors have a fresh and evidence-based approach to dealing with everything from common to rare vulval conditions. Their take on vulvodynia and dyspareunia represents an important breakthrough in the understanding of vulval pain. The first edition of this book appeared in 2010, at a time when there was very little published evidence on vulval disease. The entire text has been updated in line with modern practice. A reading list and references are included at the end of each chapter. There is further information on management, particularly in the field of long-term treatment of lichen sclerosus and on newly described conditions. The text is designed for gynaecologists and dermatologists but will also be readily understandable to primary care and family practice physicians, nurse practitioners and others working in women’s health.

Contents Foreword; Preface; Glossary; 1. The basics; 2. Using topical steroids on the vulva; 3. Red vulval rashes; 4. Things that look white; 5. Things that ulcerate, blister and erode; 6. Persistent vaginitis; 7. Lumps: benign and malignant; 8. Vulval pain and dyspareunia; 9. Vulval disease in children; 10. Myths and pearls; Index.

Additional Information Level: medical specialists/consultants

• Not a textbook: it is a handbook designed to help the busy clinician – the information is arranged by clinical presentation, making searching for an answer easy • Takes a fresh look at the difficult areas of vulval practice, especially vulvodynia – demystifies a ‘mysterious’ subject

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Pathology and Laboratory Science

Leong’s Manual of Diagnostic Antibodies for Immunohistology Third edition

Edited by Runjan Chetty University of Toronto

Kumarasen Cooper University of Pennsylvania

and Allen Gown Phenopath Laboratories, Seattle

September 2016 246 x 189 mm 350pp 64 tables 978-1-107-07778-2 Hardback £99.99

why it will sell • The third edition of the Manual of Diagnostic Antibodies for Immunohistology, fully updated with over forty new entries, outlining the specificities of monoclonal and antisera antibodies and their key uses • Highlights caveats and how to avoid the most common problems in practical application of immunohistochemistry

Providing a unique A-Z guide to antibodies for immunohistology, this is an indispensable source for pathologists to ensure the correct application of immunohistochemistry in daily practice. Each entry includes commercial sources, clones, descriptions of stained proteins/epitopes, the full staining spectrum of normal and tumor tissues, staining pattern and cellular localization, the range of conditions of immunoreactivity, and pitfalls of the antibody’s immunoprofile, giving pathologists a truly thorough quickreference guide to sources, preparation and applications of specific antibodies. Appendices provide useful quick-reference tables of antibody panels for differential diagnoses, as well as summaries of diagnostic applications. Expanded from previous editions with over forty new entries, this handbook for diagnostic, therapeutic, prognostic and research applications of antibodies is an essential desktop book for practicing pathologists as well as researchers, residents and trainees.

Contents List of contributors; Preface to the first edition; Preface to the second edition; Preface to the third edition; Introduction to the third edition; Part I. Antibodies; Part II. Appendices: Appendix 1. Selected antibody panels for specific diagnostic situations; Appendix 2. Antibody panels for lymphoid neoplasms; Appendix 3. Antibody applications.

Additional Information Level: medical specialists/consultants, specialist medical trainees

• Each entry follows a standard structure for quick and easy access and retrieval of information

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Pathology and Laboratory Science

Modern Soft Tissue Pathology Tumors and Non-Neoplastic Conditions Second edition

Edited by Markku Miettinen National Cancer Institute, Bethesda, Maryland

September 2016 276 x 219 mm 1088pp 19 b/w illus. 1163 colour illus. 83 tables 978-1-107-56727-6 Hardback with Online Resource £200.00

Fully updated throughout, the second edition of this bestselling book provides a comprehensive guide to the pathology of soft tissue tumors and tumor-like lesions. Reflecting the latest WHO classification throughout, this new edition incorporates advances in clinicopathologic, biologic and genetic studies. As such, detailed coverage of immunohistochemistry and molecular diagnostics is included for each entity. Soft tissue tumors are broadly defined to include metastatic melanomas, carcinomas, and lymphoid proliferations in soft tissue, enabling the reader to distinguish between easily confused entities. Chapters are richly illustrated throughout with high-quality colour images, depicting both typical histology and variants of each entity. Each printed copy of this new edition is also packaged with a password, providing online access to the book’s text and images. Written and edited by renowned international leaders in the field, this is an essential guide to all diagnostic modalities in soft tissue pathology.

Contents

why it will sell • Concise tables and illustrative panels allow the reader to formulate an understanding of each entity at a glance • Detailed information about immunohistochemistry and genetics is integrated into the text for each entity, allowing the reader to understand tumor biology and make use of the full panoply of diagnostic modalities • Edited by a world leader in soft tissue pathology, providing an authoritative one-stop resource for diagnostic practice

1. Overview of soft tissue tumors; 2. Radiologic evaluation of soft tissue tumors; 3. Immunohistochemistry of soft tissue tumors; 4. Genetics of soft tissue tumors; 5. Molecular genetics of soft tissue tumors; 6. Fibroblast biology, fasciitis, retroperitoneal fibrosis, and keloids; 7. Fibromas and benign fibrous histiocytomas; 8. Fibromatoses; 9. Benign fibroblastic and myofibroblastic proliferations in children; 10. Childhood fibroblastic and myofibroblastic proliferations of variable biologic potential; 11. Myxomas and ossifying fibromxxoid tumor; 12. Solitary fibrous tumor, hemangiopericytoma, and related tumors; 13. Fibroblastic and myofibroblastic neoplasms with malignant potential; 14. Lipoma variants and conditions simulating lipomatous tumors; 15. Atypical lipomatous tumors and liposarcomas; 16. Smooth muscle tumors; 17. Gastrointestinal stromal tumor (GIST); 18. Stromal tumors and tumor-like lesions of the female genital tract; 19. Angiomyolipoma and other perivascular epithelioid cell tumors (PEComas); 20. Rhabdomyomas and rhabdomyosarcomas; 21. Hemangiomas, lymphangiomas, and reactive vascular proliferations; 22. Hemangioendotheliomas, angiosarcomas, and Kaposi’s sarcoma; 23. Glomus tumor, glomangiopericytoma, myopericytoma, and juxtaglomerular tumor; 24. Nerve sheath tumors; 25. Neuroectodermal tumors: melanocytic, glial, and meningeal neoplasms; 26. Paragangliomas; 27. Primary soft tissue tumors with epithelial differentiation; 28. Malignant mesothelioma and other mesothelial proliferations; 29. Merkel cell carcinoma and metastatic and sarcomatoid carcinomas involving soft tissue; 30. Cartilage- and bone-forming tumors; 31. Small round cell tumors; 32. Alveolar soft part sarcoma; 33. Pathology of synovia and tendons; 34. Miscellaneous tumor-like lesions, and histiocytic and foreign body reactions; 35. Lymphoid, myeloid, histiocytic, and dendritic cell proliferations in soft tissues; 36. Cytology of soft tissue lesions; 37. Surgical management of soft tissue sarcoma: histologic type and grade guide surgical planning and integration of multimodality therapy; 38. Medical oncology of soft tissue sarcomas. Additional Resources: http://www.cambridge.org/9781107567276 Scratch-off code on the inside front cover of the book gives the user access to online versions of all the text and images

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Additional Information Level: medical specialists/consultants, specialist medical trainees

Pathology and Laboratory Science October 2016 276 x 219 mm 560pp 1 b/w illus. 750 colour illus. 94 tables 978-1-316-61398-6 Hardback with Online Resource c. £120.00

Silva’s Diagnostic Renal Pathology Second edition

Edited by Xin Jin (Joseph) Zhou Baylor University Medical Center, Dallas

Zoltan G. Laszik

Tibor Nadasdy

University of California, San Francisco Ohio State University

and Vivette D. D’Agati Columbia University, New York Approximately ten percent of the world population are affected by kidney diseases, which often can only be diagnosed by renal biopsy. This practical guide offers an algorithmic, deductive approach to the interpretation of this complicated procedure, covering all technical methods used for diagnosis. This new edition includes an authoritative chapter on digital renal pathology, a topic inadequately covered in current literature. All chapters have been extensively revised in light of major advances in the understanding of the pathogenesis and clinicopathological features of renal disease. Written for practising pathologists and nephrologists, this text encompasses the entire spectrum of medical renal diseases in both pediatric and adult populations. Its numerous diagnostic algorithms provide a convenient overview and a helpful guide into the detailed text, directing the reader to major patterns of interest. Including online access to over 1000 photomicrographs and diagrams, this book is also of interest to trainees in nephrology and pathology.

why it will sell • Situated on the midpoint between encyclopaedic and summary coverage • Includes a ‘clinical and pathologic’ classification scheme, which does not require prior knowledge of what the diagnosis is to find the relevant entry • Extensively revised to incorporate major advances in the pathogenesis, classification and molecular genetics of renal diseases in both native and transplant kidneys

Contents Foreword; Preface to the first edition; Preface to the second edition; 1. Renal development and anatomy; 2. Renal biopsy: the nephrologist’s viewpoint; 3. Algorithmic approach to the interpretation of renal biopsy; 4. Glomerular diseases associated with nephrotic syndrome and proteinuria; 5. Glomerular diseases associated primarily with asymptomatic or gross hematuria; 6. Infection-related glomerulonephritis, membranoproliferative pattern of glomerulonephritis and nephritic syndrome; 7. Glomerular diseases associated with crescentic glomerulonephritis (rapidly progressive glomerulonephritis); 8. Systemic lupus erythematosus and other autoimmune diseases (mixed connective tissue disease, rheumatoid arthritis, and Sjogren’s syndrome); 9. Metabolic diseases of the kidney; 10. Thrombotic microangiopathies; 11. Renal diseases associated with hematopoietic disorders or organized deposits; 12. Tubulointerstitial diseases; 13. Hypertension and vascular diseases of the kidney; 14. Cystic and developmental diseases of the kidney; 15. The ageing kidney and end stage renal disease; 16. Pathology of renal transplantation; 17. Digital renal pathology; Index. Additional Resources: http://www.cambridge.org/9781316613986 Access to over 1000 photomicrographs and diagrams

Additional Information Level: medical specialists/consultants, specialist medical trainees

www.cambridge.org/rights foreignrights@cambridge.org

Advanced Neuroradiology Cases......................10 Amaral, Lázaro Luís Faria do............................10 Anderson, Judith.............................................18 Arulkumaran, Sir Sabaratnam..........................19 Atkinson, Kerry..................................................8

Keating, Armand...............................................8 Khatri, Rakesh.................................................16

Webb, Penny.....................................................6 Wellbeing, Recovery and Mental Health...........14 Wynn, Robert....................................................9

B Bacigalupo, Andrea...........................................8 Bag, Asim K.....................................................10 Bain, Chris........................................................6 Beggs, Paul J.....................................................5 Behavioral Neurology of Dementia, The............17 Berman, Nancy G...............................................7 Best Practice in Labour and Delivery................19 Bhat, Rukhmi....................................................9 Boeve, Bradley F..............................................17 Bradford, Jennifer............................................22 Brockington, Ian..............................................13 Bronstein, Adolfo.............................................15

C Chandraharan, Edwin......................................20 Chetty, Runjan................................................23 Chronic Care Nursing......................................18 Complications of Neuroendovascular Procedures and Bailout Techniques.................................16 Cooper, Kumarasen.........................................23

D D’Agati, Vivette D............................................25 Deravin-Malone, Linda.....................................18 Dizziness.........................................................15

L Laszik, Zoltan G...............................................25 Lazarus, Hillard M..............................................8 Lempert, Thomas.............................................15 Leong’s Manual of Diagnostic Antibodies for Immunohistology.........................................23 Lin, Ted.............................................................3

M Margesson, Lynette.........................................22 McRobbie, Donald...........................................12 Miettinen, Markku...........................................24 Miller, Bruce L..................................................17 Modern Soft Tissue Pathology..........................24 Monagle, Paul...................................................9 Moore, Elizabeth A..........................................12 Mowatt, Chris...................................................3 MRI from Picture to Proton..............................12 Munker, Reinhold..............................................8

N Nadasdy, Tibor................................................25

O Oades, Lindsay................................................14

Fischer, Gayle..................................................22 Fundamentals of Anaesthesia............................3

Page, Andrew....................................................6 Parker, Robert A.................................................7 Pediatric Hematology........................................9 Pierson, Anna....................................................4 Pinnock, Colin...................................................3 Planning Clinical Research.................................7 Plunkett, Emma.................................................4 Psychoses of Menstruation and Childbearing, The..............................................................13

Gale, Robert Peter.............................................8 Geschwind, Jean-Francois H.............................11 Gonçalves, Fabricio Guimarães.........................10 Gown, Allen....................................................23 Graves, Martin J...............................................12

Qureshi, Adnan I..............................................16

E Essential Epidemiology......................................6

H Hanagandi, Prasad B.......................................10 Handbook of CTG Interpretation......................20 Handbook of Gestational Surrogacy.................21 Hematopoietic Cell Transplants..........................8

R Raymond, Jean................................................16 Returning to Work in Anaesthesia......................4 Rodriguez, Gustavo J.......................................16

Sills, E. Scott....................................................21 Silva’s Diagnostic Renal Pathology...................25 Slade, Mike.....................................................14 Smith, Tim.........................................................3 Soulen, Michael C............................................11

Impacts of Climate Change on Allergens and Allergic Diseases............................................5 Interventional Oncology...................................11

J Jarden, Aaron..................................................14 Johnson, Emily..................................................4

Vulva, The.......................................................22

Z Zhou, Xin Jin (Joseph)......................................25

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