Chemical and Biomedical Engineering Cluster 2012

Chemical and Biomedical Engineering 2012

Biomedical Engineering

CONTENTS Biomedical Engineering Chemical Engineering

3 14

CAMBRIDGE TEXTS IN

PRUITT: Mechanics of Biomaterials PPC C M Y BLK

Cover illustration (left top): bileaflet heart valve (Craig Hansen); (left center): total hip replacement (Amir Mehdizadeh); (left bottom): TMJ dental implant (Craig Hansen); (right): topographical surface damage map of femoral head (Eli Patten).

Fundamental Principles for Implant Design

“Chemical engineering is the field of applied science that employs physical, chemical, and biochemical rate processes for the betterment of humanity.” This opening sentence of Chapter 1 is the underlying paradigm of chemical engineering. Chemical Engineering: An Introduction is designed to enable the student to explore the activities in which a modern chemical engineer is involved by focusing on mass and energy balances in liquid-phase processes. Applications explored include the design of a feedback level controller, membrane separation, hemodialysis, optimal design of a process with chemical reaction and separation, washout in a bioreactor, kinetic and mass transfer limits in a two-phase reactor, and the use of a membrane reactor to overcome equilibrium limits on conversion. Mathematics is employed as a language at the most elementary level. Professor Morton M. Denn incorporates design meaningfully; the design and analysis problems are realistic in format and scope. Students using this text will appreciate why

Lisa A. Pruitt and Ayyana M. Chakravartula

they need the courses that follow in the core curriculum.

MORTON M. DENN is the Albert Einstein Professor of Science and Engineering and Director of the Benjamin Levich Institute for Physico-Chemical Hydrodynamics at the City College of New York, CUNY. Prior to joining CCNY in 1999, he was Professor of Chemical Engineering at the University of California, Berkeley, where he served as Department Chair, as well as Program Leader for Polymers and Head of Materials Chemistry in the Materials Sciences Division of the Lawrence Berkeley National Laboratory. He previously taught chemical engineering at the University of Delaware, where he was the Allan P. Colburn Professor. Professor Denn was Editor of the AIChE Journal from 1985 to 1991 and Editor of the Journal of Rheology from 1995 to 2005. He is the recipient of a Guggenheim Fellowship; a Fulbright Lectureship; the Professional

All other enquiries: telephone +44 (0) 1223 312393 or email information@cambridge.org

Progress, William H. Walker, Warren K. Lewis, Institute Lectureship, and Founders Awards of the American Institute of Chemical Engineers; the Chemical Engineering Lectureship of the American Society for Engineering Education; and the Bingham Medal and Distinguished Service Awards of the Society of Rheology. He is a member of the National Academy of Engineering and the American Academy of Arts and Sciences, and he received an honorary DSc from the University of Minnesota. His previous books are Optimization by Variational Methods; Introduction to Chemical Engineering Analysis, coauthored with T. W. Fraser Russell; Stability of Reaction and Transport Processes; Process Fluid Mechanics; Process Modeling; and Polymer Melt Processing: Foundations in Fluid Mechanics and Heat Transfer.

Cover photo: Stellarator II. © Kim Dylla. Used with permission.

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Cambridge Texts in Biomedical Engineering

Mechanics of Biomaterials

2011 246 x 189 mm 696pp 375 b/w illus. 35 tables 115 exercises 978-0-521-76221-2 Hardback £65.00

Fundamental Principles for Implant Design Lisa A. Pruitt

eBook available

University of California, Berkeley

TEXTBOOK

M O R T O N M. D E N N

CAMBRIDGE TEXTS IN BIOMEDICAL ENGINEERING Series Editors Professor W. Mark Saltzman, Yale University Professor Shu Chien, University of California, San Diego

and complex stress states, yielding and failure theories, and fracture mechanics. The final section on clinical aspects of medical devices provides crucial information on FDA regulatory issues and presents case studies in four key clinical areas: orthopedics, cardiovascular devices, dentistry, and soft tissue implants. Each chapter ends with a list of topical questions, making this an ideal course textbook for senior undergraduate and graduate students, and also a self-study tool for engineers, scientists, and clinicians.

“Mechanics of Biomaterials is the textbook I have been waiting for. … an outstanding text and reference book that should be required reading for all who aspire to design, develop and evaluate medical devices.”

Jeremy L. Gilbert, Syracuse University

Lisa A. Pruitt is the Lawrence Talbot Chair of Engineering at the University of California, Berkeley and also serves as an Adjunct Professor in the Department of Orthopedic Surgery at the University of California, San Francisco. She recently served as the Associate Dean of Lifelong Learning and Outreach Education in the College of Engineering and has received numerous awards including the Presidential Award for Excellence in Science, Mathematics, and Engineering Mentoring (2004) and the Graduate Student Instructor Mentor Award from UC Berkeley (2009).

“The authors have written a detailed yet easy-to-read book that can be used by materials scientists and biomedical engineers… rich in practical examples of biomaterials used in permanent implants currently on the market.”

Stephen Spiegelberg, Cambridge Polymer Group, Inc., MA, USA

Ayyana M. Chakravartula received her Ph.D. in Mechanical Engineering from the University of California, Berkeley in 2005. She currently works at Exponent, Inc. in Menlo Park, CA in its Mechanics and Materials practice. She has worked as a research scientist at the Cambridge Polymer Group in Boston, MA, and has served as an Adjunct Lecturer at Boston University. She has mentored numerous students, interns, and research assistants in her graduate and post-graduate career.

“…provides a much needed comprehensive resource for engineers, physicians, and implant designers at every level of training and practice.”

Michael Ries, University of California, San Francisco

Cover illustration (left top): bileaflet heart valve (Craig Hansen); (left center): total hip replacement (Amir Mehdizadeh); (left bottom): TMJ dental implant (Craig Hansen); (right): topographical surface damage map of femoral head (Eli Patten).

BIOMEDICAL ENGINEERING

Mechanics of

Biomaterials Fundamental Principles for Implant Design

Lisa A. Pruitt and Ayyana M. Chakravartula

Biosimulation

Exponent, Inc., Menlo Park, California

Chemical Engineering

CAMBRIDGE TEXTS IN

Teaching mechanical and structural biomaterials concepts for successful medical implant design, this self-contained text provides a complete grounding for students and newcomers to the field.

Split into three sections – Materials, Mechanics, and Case Studies – it begins with a review of sterilization, biocompatibility, and foreign body response before presenting the fundamental structures of synthetic biomaterials and natural tissues. Mechanical behavior of materials is then discussed in depth, covering elastic deformation, viscoelasticity and time-dependent behavior, multiaxial loading

www.cambridge.org/9780521762212

and Ayyana M. Chakravartula

AN INTRODUCTION

Cover design by Alice Soloway

Prices and publication dates are correct at the time of going to press but are subject to alteration without notice.

Chemical Engineering AN INTRODUCTION

Further information about Engineering titles: Hollie Fortey (hfortey@cambridge.org)

“…provides a much needed comprehensive resource for engineers, physicians, and implant designers at every level of training and practice.”

Michael Ries, University of California, San Francisco

Biomaterials

TEXTBOOK

Mechanics of Biomaterials

Ayyana M. Chakravartula received her Ph.D. in Mechanical Engineering from the University of California, Berkeley in 2005. She currently works at Exponent, Inc. in Menlo Park, CA in its Mechanics and Materials practice. She has worked as a research scientist at the Cambridge Polymer Group in Boston, MA, and has served as an Adjunct Lecturer at Boston University. She has mentored numerous students, interns, and research assistants in her graduate and post-graduate career.

Mechanics of

HIGHLIGHT

maxillofacial devices; 16. Soft tissue replacements; Appendix A. Selected topics from mechanics of materials; Appendix B. Table of material properties of engineering biomaterials and tissues; Appendix C. Teaching methodologies in biomaterials; Glossary; List of symbols.

33

Pruitt and Chakravartula

“The authors have written a detailed yet easy-to-read book that can be used by materials scientists and biomedical engineers… rich in practical examples of biomaterials used in permanent implants currently on the market.”

Stephen Spiegelberg, Cambridge Polymer Group, Inc., MA, USA

“Mechanics of Biomaterials is the textbook I have been waiting for. … an outstanding text and reference book that should be required reading for all who aspire to design, develop and evaluate medical devices.”

Jeremy L. Gilbert, Syracuse University

BIOMEDICAL ENGINEERING

DENN

Lisa A. Pruitt is the Lawrence Talbot Chair of Engineering at the University of California, Berkeley and also serves as an Adjunct Professor in the Department of Orthopedic Surgery at the University of California, San Francisco. She recently served as the Associate Dean of Lifelong Learning and Outreach Education in the College of Engineering and has received numerous awards including the Presidential Award for Excellence in Science, Mathematics, and Engineering Mentoring (2004) and the Graduate Student Instructor Mentor Award from UC Berkeley (2009).

Book proposals: Sarah Marsh (smarsh@cambridge.org)

Series Editors Professor W. Mark Saltzman, Yale University Professor Shu Chien, University of California, San Diego

Mechanics of Biomaterials

CAMBRIDGE TEXTS IN BIOMEDICAL ENGINEERING

Pruitt and Chakravartula

Useful contacts

Teaching mechanical and structural biomaterials concepts for successful medical implant design, this self-contained text provides a complete grounding for students and newcomers to the field.

Split into three sections – Materials, Mechanics, and Case Studies – it begins with a review of sterilization, biocompatibility, and foreign body response before presenting the fundamental structures of synthetic biomaterials and natural tissues. Mechanical behavior of materials is then discussed in depth, covering elastic deformation, viscoelasticity and time-dependent behavior, multiaxial loading and complex stress states, yielding and failure theories, and fracture mechanics. The final section on clinical aspects of medical devices provides crucial information on FDA regulatory issues and presents case studies in four key clinical areas: orthopedics, cardiovascular devices, dentistry, and soft tissue implants. Each chapter ends with a list of topical questions, making this an ideal course textbook for senior undergraduate and graduate students, and also a self-study tool for engineers, scientists, and clinicians.

Biomedical Engineering

PRUITT: Mechanics of Biomaterials PPC C M Y BLK

This catalogue contains a selection of our most recent publishing in this area. Please visit our website for a full and searchable listing of all our titles in print and also an extensive range of news, features and resources. Our online ordering service is secure and easy to use.

Teaching mechanical and structural biomaterial concepts for successful implant design, this self-contained text is suitable for engineers, scientists and clinicians. Medical device case studies (including orthopedics, cardiovascular medicine, dentistry and soft tissues), step-by-step design guidelines and problem sets throughout, make this book ideal for course use and for self study.

‘Mechanics of Biomaterials is the textbook I have been waiting for. … an outstanding text and reference book that should be required reading for all who aspire to design, develop and evaluate medical devices.’

Jeremy L. Gilbert, Syracuse University

Contents: Part I. Materials: 1. Biocompatibility, sterilization and materials selection for implant design; 2. Metals for medical implants; 3. Ceramics; 4. Polymers; 5. Mechanical behavior of structural tissues; Part II. Mechanics: 6. Elasticity; 7. Viscoelasticity; 8. Failure theories; 9. Fracture mechanics; 10. Fatigue; 11. Friction, lubrication and wear; Part III. Case Studies: 12. Regulatory affairs and testing; 13. Orthopedics; 14. Cardiovascular devices; 15. Oral and

Simulation of Living Systems Daniel A. Beard Medical College of Wisconsin

A hands-on guide to devising, designing and analysing simulations of biophysical processes for applications in biological and biomedical sciences. Practical examples are given throughout, representing real-world case studies of key application areas, and all data and complete codes for simulation and data analysis are provided online.

Contents: 1. Introduction to simulation of biological systems; 2. Transport and reaction of solutes in biological systems; 3. Physiologically-based pharmacokinetic modeling; 4. Cardiovascular systems simulation; 5. Chemical reaction systems: thermodynamics; 6. Chemical reaction systems: kinetics; 7. Chemical reaction systems: large-scale systems simulation; 8. Cellular electrophysiology; 9. Appendices: mathematical and computational techniques.

Cambridge Texts in Biomedical Engineering

2012 247 x 174 mm 300pp 115 b/w illus. 19 tables 50 exercises 978-0-521-76823-8 Hardback £55.00 www.cambridge.org/9780521768238

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Biomedical Engineering

TEXTBOOK

Numerical and Statistical Methods for Bioengineering Applications in MATLAB Michael R. King and Nipa A. Mody

Biomedical Engineering TEXTBOOK

TEXTBOOK

Introduction to Medical Imaging

FORTHCOMING

Physics, Engineering and Clinical Applications Nadine Barrie Smith Pennsylvania State University

Cornell University, New York

and Andrew Webb

The first MATLAB-based numerical methods textbook specifically for bioengineers, including topics on hypothesis testing, plus numerous examples drawn exclusively from biomedical engineering applications.

This is an ideal core text for onesemester undergraduate courses, and is also a valuable reference for anyone interested in the quantitative aspects of biology research.

Covering the basics of X-rays, CT, PET, nuclear medicine, ultrasound, and MRI, this textbook is for a one-semester senior undergraduate/graduate course in medical imaging. Together with the state-of-the-art concepts and theory, it also provides relevant clinical applications, solved and open-ended example problems, and future prospects for the field.

‘I think this book is a winner … [it] is really easy to read and places frameworks for numerical analysis into realistic bioengineering concepts that students will find familiar and relevant. This is most evident in the excellent boxed examples, but also in many of the homework problems.’

K. Jane Grande-Allen, Rice University Cambridge Texts in Biomedical Engineering

2010 246 x 189 mm 594pp 102 b/w illus.

978-0-521-87158-7 Hardback £65.00 eBook available

www.cambridge.org/9780521871587

Leiden University Medical Center

times. Whether you’re a physician with an idea, an engineer or a businessman, this is a unique and powerful resource.’

Fundamentals of Systems Biology

John Abele, Founder Chairman, Boston Scientific

Integrating Experiments with Modeling Jason Papin, Timothy Allen Shayn Pierce and Jeff Saucerman

‘… fascinating … I would recommend this book strongly to SMEs … in Europe who wish to penetrate the American market with medical device related products.’

Scope

University of Virginia

Practical introduction to the integration of experimental data and mathematical models needed to study life at a systems-wide level.

Cambridge Texts in Biomedical Engineering

246 x 189 mm 400pp 978-0-521-19641-3 Hardback c. £70.00 Publication January 2013 www.cambridge.org/9780521196413

Cambridge Texts in Biomedical Engineering

2010 246 x 189 mm 296pp 217 b/w illus. 10 tables 137 exercises 978-0-521-19065-7 Hardback £45.00 eBook available

www.cambridge.org/9780521190657

TEXTBOOK

Biodesign The Process of Innovating Medical Technologies Stefanos Zenios, Josh Makower Paul Yock, Todd J. Brinton Uday N. Kumar, Lyn Denend and Thomas M. Krummel Stanford University, California

Recognise market opportunities, master the design process, and develop business acumen with this step-by-step ‘how-to’ guide for medical technology innovation.

‘Everything you ever wanted to know about medical device entrepreneurship and more. Paul, Josh and Stefanos have led an A class team of experienced device company builders to produce a reference document to guide an aspiring device entrepreneur through all the challenges of getting an idea to market. These are tough

Want to hear more from us? Visit www.cambridge.org/alerts

Contents: Preface; Community; Biographies; Glossary; Part I. Identify; Section 1. Needs Finding: 1. Strategic focus; 2. Observation and problem identification; 3. Need statement development; Case study; Section 2. Needs Screening: 4. Disease state fundamentals; 5. Treatment options; 6. Stakeholder analysis; 7. Market analysis; 8. Needs filtering; Case study; Part II. Invent; Section 3. Concept Generation: 9. Ideation and brainstorming; 10. Concept screening; Case study; Section 4. Concept Selection: 11. Intellectual property basics; 12. Regulatory basics; 13. Reimbursement basics; 14. Business models; 15. Prototyping; 16. Final concept selection; Case study; Part III. Implement; Section 5. Development Strategy and Planning: 17. IP strategy; 18. R&D strategy; 19. Clinical strategy; 20. Regulatory strategy; 21. Quality and process management; 22. Reimbursement strategy; 23. Marketing and stakeholder strategy; 24. Sales and distribution strategy; 25. Competitive advantage and business strategy; Case study; Section 6. Integration: 26. Operating plan and financial model; 27. Business plan development; 28. Funding sources; 29. Licensing and alternate pathways; Case study; Index.

2009 276 x 219 mm 778pp 106 b/w illus. 79 tables 978-0-521-51742-3 Hardback

£61.00

eBook available

www.cambridge.org/9780521517423

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6

Biomedical Engineering TEXTBOOK

Biomedical Engineering for Global Health Rebecca Richards-Kortum Rice University, Houston

Can technology transform world health? For visionary general science and biomedical engineering courses, Rebecca Richards-Kortum examines biomedical technology and the regulatory, economic, social and ethical issues surrounding global health. With engaging learning features including classroom activities, project assignments and homework problems, this textbook will inspire undergraduates to find solutions.

‘Professor Richards-Kortum has been in the forefront of giving bioengineers a conscience. This book is an excellent first step in educating engineers as to medical problems in the developing worlds and ways in which bioengineers can make a difference.’

Paul Yager, Department of Bioengineering, University of Washington, Seattle

Contents: Preface; 1. Emerging medical technologies: high stakes science and the need for technology assessment; 2. Bioengineering and technology assessment; 3. Health and economic data: a global comparison; 4. World health and global health challenges; 5. Healthcare systems: a global comparison; 6. Healthcare costs vs. time: trends and drivers; 7. The evolution of technology: scientific method, engineering design, and translational research; 8. Prevention of infectious disease; 9. Ethics of clinical research; 10. Technologies for early detection and prevention of cancer; 11. Cost-effectiveness of screening for disease; 12. Technologies

Biomedical Engineering for treatment of heart disease; 13. Clinical trial design and sample size calculation; 14. Technology diffusion; 15. Regulation of health care technologies; 16. Future of bioengineering and world health; Index.

Introduction to the Science of Medical Imaging

Cambridge Texts in Biomedical Engineering

University of Pennsylvania

2009 276 x 219 mm 416pp 114 b/w illus. 60 tables 978-0-521-87797-8 Hardback

Biological systems are characterized by complex structures that are invisible to the human eye. Biomedical imaging such as MRI, CT, ultrasound enable us to view these structures non-invasively.

This book describes and illustrates how these images are created, analyzed and applied to important biomedical problems such as diseases.

£53.00

eBook available

www.cambridge.org/9780521877978

An Introduction to Modeling of Transport Processes Applications to Biomedical Systems Ashim Datta and Vineet Rakesh Cornell University, New York

Organised around problem solving, this book introduces the reader to computational simulation of biomedical transport processes, bridging fundamental theory with real-world applications. Step-by-step instructions enable a newcomer to get started immediately and the inclusion of property data and case studies provide usable models that can be applied further afield.

Cambridge Texts in Biomedical Engineering

2009 246 x 189 mm 532pp 135 b/w illus. 57 tables 147 exercises 978-0-521-11924-5 Hardback £47.00 eBook available

www.cambridge.org/9780521119245

Edited by R. Nick Bryan

‘Very well written … Excellent images and diagrams … concise and up to date … a landmark text on the science of image interpretation. The authors manage to make a very complex subject very readable … relevant figures are exceptional …’

BMA Medical Book Awards reviewer

Contents: Preface; Part I. Introduction: 1. What is an image?; 2. How to make an image; 3. How to analyze an image; Part II. Biomedical Images: 4. Nuclear medicine; 5. X-ray: non-ionizing radiation; 6. Ultrasound; 7. Magnetic resonance imaging; 8. Optical imaging; Part III. Sample Labeling: 9. Contrast agents; 10. Molecular labeling; Part IV. Image Analysis: 11. Human observer; 12. Digital image processing; 13. Registration and atlas building; 14. Statistical atlases; Part V. Biomedical Applications: 15. Morphological imaging; 16. Physiological imaging; 17. Molecular imaging; Appendices: 1. Linear systems; 2. Transforms and k space; 3. Probability, Bayesian statistics and information theory; Index.

2009 246 x 189 mm 334pp 159 b/w illus. 31 tables 978-0-521-74762-2 Paperback

Ultra Low Power Bioelectronics Fundamentals, Biomedical Applications, and Bio-Inspired Systems Rahul Sarpeshkar Massachusetts Institute of Technology

Learn how to architect ultra low power robust electronics with applications to implantable and non-invasive medicine, and how bio-inspired principles from cell biology and neurobiology can revolutionize low power electronics design, with this all-inclusive guide.

Efficient, sustainable energy harvesting is also covered, and a wealth of practical examples and case studies are included. ‘… an excellent overview of ten key fundamental principles related to ultra low power circuit and system design. Examples of many practical, experimental micro-power systems in cardiac, neural,and other medicalelectronics applications make the text highly useful. Practitioners in this field will gain insight from his system-level analysis, which is presented at a level deeper than that found in most texts.

In fact, the focus on systems thinking and connections made to a diverse set of problems – natural and man-made, from medical implants, to cells, to low-power cars – truly sets this book apart.’

Tim Denison, Medtronic Fellow 2010 247 x 174 mm 908pp 406 b/w illus. 15 tables 150 exercises 978-0-521-85727-7 Hardback £52.00 eBook available

www.cambridge.org/9780521857277

£79.00

eBook available

www.cambridge.org/9780521747622

Order online at www.cambridge.org/chembio

Order online at www.cambridge.org/chembio

7

Biomedical Engineering

8

Multiscale Modeling of the Skeletal System Marco Viceconti Istituti Ortopedici Rizzoli, Bologna, Italy

Systematically working from the whole body down to the cellular level, this book presents an integrative, multiscale computational approach to skeletal research. Addressing biomechanical and mechanobiological processes, the reader will learn how computational modeling can determine the relationship between bone mechanics and disease.

‘Professor Viceconti is one of the pioneers of the integrative approach to biological systems and his book is a beautiful illustration of this approach. Beautiful in all senses: sound intellectual argument, clear informative illustrations, fascinating practical applications, and it forms a sustained development of a field of research that is fundamental to the success of any attempt to create the Virtual Physiological Human.’

Denis Noble, University of Oxford Edited by Romain Brette and Alain Destexhe

2011 247 x 174 mm 222pp 40 b/w illus.

978-0-521-76950-1 Hardback £65.00 www.cambridge.org/9780521769501

Handbook of

Neural Activity Measurement

Multiscale Modeling of Cancer An Integrated Experimental and Mathematical Modeling Approach Vittorio Cristini University of Texas Health Science Center, Houston

and John Lowengrub

Biomedical Engineering with a biological background, the reader is introduced to the principles of mathematical modeling, before being guided through case studies that demonstrate how modeling can aid our understanding of tumour biology.

The Mechanics of the Circulation

2010 247 x 174 mm 298pp 55 b/w illus. 5 tables 978-0-521-88442-6 Hardback

University of Cambridge £83.00

eBook available

www.cambridge.org/9780521884426

Handbook of Neural Activity Measurement Edited by Romain Brette Ecole Normale Supérieure, Paris

and Alain Destexhe Centre National de la Recherche Scientifique (CNRS), Paris

Leading experts describe the various existing techniques for measuring neural activity (for example, intracellular recording and electroencephalograms).

Readers will come to understand the physical principles underlying each technique and the precise relationship between the measured signals and neural activity.

2012 247 x 174 mm 254pp 95 b/w illus. 30 colour illus.

978-0-521-51622-8 Hardback c. £70.00 Publication August 2012 www.cambridge.org/9780521516228

Second edition C. G. Caro Imperial College London

T. J. Pedley R. C. Schroter Imperial College London

and W. A. Seed Imperial College London

Assisted by K. H. Parker Imperial College London

Finally back in print, this classic book is of value to students, researchers and practitioners in bioengineering, physiology and human and veterinary medicine, particularly those working in the cardiovascular field. It is also useful for engineers and physical scientists with multidisciplinary interests.

‘This splendid book is so well written that one would seriously question the vocation of an investigator who couldn’t understand it. It is essential reading for anyone who is interested in the mechanics of the circulation. The normally incomprehensible mechanical laws are explained so clearly that even the non-mathematically minded will have no difficulty, which makes me very sorry that it was not available when I was grappling with these problems.’

David Mendel, Journal of the Royal Society of Medicine 2011 228 x 152 mm 550pp 285 b/w illus. 15 tables 978-0-521-15177-1 Paperback £29.99 www.cambridge.org/9780521151771

Mathematical Foundations and Biomechanics of the Digestive System Roustem N. Miftahof and Hong Gil Nam Pohang University of Science and Technology, Republic of Korea

Mathematical models are used to explain and study organ biomechanics of the abdominal viscera. Beginning with the fundamentals of thin shell theory, it leads to description of the function of abdominal organs. Finite deformations, effects of boundary conditions, electrodynamics dynamics, related medical conditions and effects of drugs are investigated.

‘Biomedical engineers, gastrointestinal physiologists, medical physicists, and experts in drug discovery will find the insights and comprehensiveness of this mathematical modeling framework to have breakthrough potential … this book introduces a model that explains drug effects, their interactions, and reveals the mechanism for pathophysiological consequences of common disorders.’

Michael W. Vannier, University of Chicago Medical Center 2010 247 x 174 mm 240pp 237 b/w illus. 42 exercises 978-0-521-11662-6 Hardback

£77.00

eBook available

www.cambridge.org/9780521116626

University of California, Irvine

Uniquely connecting theory with experimental data, this book highlights the potential of advanced computational methods in cancer research. Beginning

eBooks available at www.cambridge.org/ebookstore

eBooks available at www.cambridge.org/ebookstore

9

Biomedical Engineering

10

Complex Webs

TEXTBOOK

Anticipating the Improbable Bruce J. West

Partial Differential Equation Analysis in Biomedical Engineering

Army Research Office

and Paolo Grigolini University of North Texas

Presenting the common principles, algorithms, and tools governing network behaviour, dynamics, and complexity, this book synthesises modern mathematical developments with the broad range of network applications of interest to the engineer and system scientist. It is richly illustrated with real-world examples from physiology, bioengineering, biophysics, and informational and social networks.

Partial Differential Equation Analysis in Biomedical Engineering Case Studies with Matlab William E. Schiesser

Biomedical Engineering

‘Recent books highlighting different aspects of network science can be roughly separated into popular works that lay out an integrated scientific view of humans and modern technology; manuals and references focused on specific application areas such as biophysics, econophysics, or sociophysics; and texts that explore advanced networks-related topics that go beyond particular disciplines.

Complex Webs most closely matches the last (and smallest) category, as it interweaves various topics from statistical physics to support the understanding of complex networks; perhaps in the future those topics will form the foundation of a network science.’

H. Eugene Stanley, Physics Today 2010 247 x 174 mm 386pp 110 b/w illus. 6 tables 27 exercises 978-0-521-11366-3 Hardback £45.00 eBook available

www.cambridge.org/9780521113663

Case Studies with Matlab William E. Schiesser

Dendrimers, Dendrons, and Dendritic Polymers Discovery, Applications and the Future Donald A. Tomalia NanoSynthons, LLC

Jørn B. Christensen University of Copenhagen

Lehigh University, Pennsylvania

and Ulrik Boas

Aimed at graduates and researchers, this introduction to computer-based partial differential equation (PDE) modeling provides readers with the practical tools necessary to develop and use mathematical models in biomedical engineering. With step-bystep guidelines and detailed examples, the reader will learn how PDE analysis is formulated, implemented and tested.

Technical University of Denmark, Lyngby

2012 247 x 174 mm 350pp 20 b/w illus. 15 tables 978-1-107-02280-5 Hardback c. £65.00 Publication July 2012 www.cambridge.org/9781107022805

Cellular Materials in Nature and Medicine Lorna J. Gibson

Dendrimer science has exploded onto the polymer science scene, presenting a completely new polymeric architecture.

It offers unique architecturally driven properties which promise exciting advancements in nanotechnology.

This book presents the history of dendrimer discovery, synthetic strategies, characterisation methodologies, dendritic effects and the future impact on nanotechnology and commercial applications.

2012 247 x 174 mm 344pp 269 b/w illus. 2 tables 978-0-521-51580-1 Hardback c. £60.00 Publication August 2012 www.cambridge.org/9780521515801

TEXTBOOK

Micro- and Nanoscale Fluid Mechanics Transport in Microfluidic Devices Brian Kirby Cornell University, New York

This text brings together several areas that are often taught separately – namely fluid mechanics, electrodynamics, and interfacial chemistry and electrochemistry – with a focused goal of preparing the modern microfluidics researcher to analyse and model continuum fluid mechanical systems encountered when working with microand nanofabricated devices.

2010 253 x 215 mm 534pp 228 b/w illus. 23 tables 360 exercises 978-0-521-11903-0 Hardback £75.00 eBook available

www.cambridge.org/9780521119030

ElectrokineticallyDriven Microfluidics and Nanofluidics Hsueh-Chia Chang University of Notre Dame, Indiana

Massachusetts Institute of Technology

and Leslie Y. Yeo

Michael F. Ashby

Monash University, Victoria

University of Cambridge

In this book, Leslie Yeo and Hsueh-Chia Chang aim to elucidate the fundamental mechanisms governing both DC and AC electrokinetic phenomena with a particular emphasis on the practical design of microfluidic and nanofluidic devices for a variety of biological applications.

and Brendan A. Harley University of Illinois, Urbana-Champaign

Describing the structure and mechanics of a wide range of natural materials with a honeycomb- or foam-like structure (e.g. wood, cork, trabecular bone and coral), this book shows how models for cellular materials can be applied in medicine, such as metal foams in orthopedics and porous scaffolds for tissue engineering.

2010 253 x 215 mm 526pp 283 b/w illus.

978-0-521-86025-3 Hardback £72.00 www.cambridge.org/9780521860253

2010 247 x 174 mm 320pp 149 b/w illus. 21 colour illus. 34 tables 978-0-521-19544-7 Hardback £52.00 www.cambridge.org/9780521195447

Order online at www.cambridge.org/chembio

Order online at www.cambridge.org/chembio

11

Biomedical Engineering

12

TEXTBOOK

Essentials of Microand Nanofluidics With Applications to the Biological and Chemical Sciences A. Terrence Conlisk Ohio State University Dillon BIOPHYSICS

s book offers rigorous but accessible

anations of basic mechanisms and

presents biomedical applications in a

ner that heightens understanding of

iological context. The book presents

iophysical basis of an impressive

ber of physiological and biochemical

hanisms in a manner that is not found

aditional textbooks. It should certainly

to broaden the knowledge base of

ents and researchers in biomedicine

ife science and thereby facilitate

s-disciplinary understanding and

action.”

BIOPHYSICS A Physiological Approach

Hellstrand, Lund University, Sweden

ck F. Dillon is Professor in the

artment of Physiology at Michigan

e University. He has taught physiology

Patrick F. Dillon

more than 30 years, ranging from

school to medical school level. He

awarded the Outstanding Faculty

d from Michigan State University in

gnition of his teaching achievements.

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Mechanics of the Cell

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ed, with new chapters on control and organization in ull color which enhances the

urther applications, this

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s at Simon Fraser University, past 20 years, and he now

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nd theoretical perspectives.

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ng their architecture and

nterdisciplinary fields of cell

david Boal

This book introduces students to the physical principles to analyze fluid flow in micro and nano-size devices.

This is the first book that unifies the thermal sciences with electrostatics and electrokinetics and colloid science; electrochemistry; and molecular biology.

This textbook includes exercises, modern examples and applications, and a solutions manual available to qualified instructors.

2012 253 x 177 mm 548pp 117 b/w illus. 40 tables 170 exercises 978-0-521-88168-5 Hardback TBA Publication July 2012 www.cambridge.org/9780521881685

TEXTBOOK

Biophysics A Physiological Approach Patrick F. Dillon Michigan State University

Specifically tailored to life science students, this textbook outlines the important physical ideas, equations and examples at the heart of contemporary physiology, along with the organisation necessary to understand that knowledge. The equations are designed to help students understand biological principles, with a particular emphasis on human biology.

‘The book presents the biophysical basis of an impressive number of physiological and biochemical mechanisms in a manner that is not

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Biomedical Engineering found in traditional textbooks. It should certainly help to broaden the knowledge base of students and researchers in biomedicine and life science and thereby facilitate cross-disciplinary understanding and interaction.’

Per Hellstrand, Lund University, Sweden 2012 247 x 174 mm 314pp 162 b/w illus. 10 tables 978-1-107-00144-2 Hardback 978-0-521-17216-5 Paperback

£75.00 £38.00

eBook available

www.cambridge.org/9781107001442

TEXTBOOK

Mechanics of the Cell Second edition David Boal Simon Fraser University, British Columbia

Exploring the mechanical features of biological cells, this second edition now covers complex filaments, the cell division cycle, cell control and organisation, and fluctuation phenomena. In full color and with over 300 end-of-chapter exercises, this textbook is ideal for advanced undergraduate and graduate students in physics and biomedical engineering.

Review of the first edition: … for graduate students in the general field and for biotechnologists required to consider added dimensions to their work this book represents a comprehensive text that ought to make it a standard reference for many years.’

Ian Jones, Chemistry in Britain 2012 246 x 189 mm 622pp 282 colour illus. 283 exercises 978-0-521-11376-2 Hardback £90.00 978-0-521-13069-1 Paperback £50.00 eBook available

Systems Biology: Simulation of Dynamic Network States Bernhard Ø. Palsson University of California, San Diego

Large omics data sets are difficult to interpret and use, but this practical book teaches how to build complex dynamical models of biochemical networks and simulate their responses. All examples in the text are available in MATLAB and MATHEMATICA® workbooks, allowing easy hands-on practice.

2011 247 x 174 mm 332pp 126 b/w illus.

978-1-107-00159-6 Hardback £45.00 eBook available

www.cambridge.org/9781107001596

Cellular Mechanotransduction Diverse Perspectives from Molecules to Tissues Edited by Mohammad R. K. Mofrad

Plasma Medicine Applications of Low Temperature Gas Plasmas in Medicine and Biology Edited by M. Laroussi Old Dominion University, Virginia

M. G. Kong Loughborough University

G. Morfill Max-Planck-Institut für Plasmaphysik, Garching, Germany

and W. Stolz Ludwig-Maximilians-Universität Munchen

The first book dedicated exclusively to plasma medicine, covering the fundamental theory and examples of its applications in different fields. Devised to meet the needs of researchers from different scientific communities, this volume is a reference tool for graduate students and researchers in physics, engineering, biology, medicine and biochemistry.

2012 247 x 174 mm 416pp 140 b/w illus. 15 tables 978-1-107-00643-0 Hardback c. £75.00 Publication May 2012 www.cambridge.org/9781107006430

University of California, Berkeley

and Roger D. Kamm Massachusetts Institute of Technology

This book focuses on the process of stress sensing and transducing mechanical force into biochemical signals. It helps define mechanomics, which describes the mechanical state of a biological system.

2009 253 x 215 mm 478pp 240 b/w illus. 8 colour illus. 4 tables 978-0-521-89523-1 Hardback £77.00 www.cambridge.org/9780521895231

13

The Toxicology of Carbon Nanotubes Edited by Kenneth Donaldson

Plasma Medicine Applications of Low Temperature Gas Plasmas in Medicine and Biology

University of Edinburgh

M. Laroussi, M. Kong, G. Morfill and W. Stolz

Craig Poland Institute of Occupation Medicine

Rodger Duffin University of Edinburgh

and James Bonner North Carolina State University

Compiled by leading experts, this is the first book dedicated to this subject. It provides state-of-the-science information, from the aerodynamic behaviour of carbon nanotubes to their

The Toxicology of Carbon Nanotubes Ed i T Ed by

Ken Donaldson, Craig Poland, Rodger Duffin and James Bonner

www.cambridge.org/9780521113762

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Biomedical Engineering

Chemical Engineering

2012 247 x 174 mm 264pp 58 b/w illus.

978-1-107-00837-3 Hardback c. £85.00 Publication July 2012 www.cambridge.org/9781107008373

Chemical Engineering HIGHLIGHT TEXTBOOK

Core Technology and Applications Min Gu Swinburne University of Technology, Victoria

Damian Bird Daniel Day

University of Minnesota

TEXTBOOK

Ling Fu Huazhong University of Science and Technology

and Dru Morrish Swinburne University of Technology, Victoria

Covering key techniques for optical microscopy and micro-fabrication, this book provides the first detailed treatment of femtosecond laserbased biophotonics. After a review of the techniques for nonlinear and multiphoton imaging, applications for laser-based manipulation of microparticles are introduced. The final chapter focuses on the burgeoning field of femtosecond micro-engineering. £83.00

eBook available

www.cambridge.org/9780521882408

This revised and expanded edition of a groundbreaking textbook provides a four-step process for chemical product design: needs, ideas, selection and manufacture. Numerous real-world examples and homework problems give ample illustrative and assessment material, whilst four new chapters set out the different product types (commodities, devices, molecules/drugs and microstructures).

‘I have been anticipating the launch of this book since Dr Moggridge told me back in 2009 that he had been working on the second edition. This is the long-awaited update of the book which was the first of its kind in the chemical engineering literature. The book had served as the foundation of my chemical product design course.

Cussler and Moggridge’s clear writing style and abundance of real-world examples in the book make it a musthave for any faculty interested in this fast emerging field of product design in chemical engineering.’

Sin-Moh Cheah, Singapore Polytechnic

eBooks available at www.cambridge.org/ebookstore

Katholieke Universiteit Leuven, Belgium

and Norman J. Wagner University of Delaware

With material presented in an introductory manner, and complex mathematical derivations kept to a minimum, this is the first book devoted to the comprehensive study of colloidal rheology in all its aspects. An essential guide for industrial researchers and practitioners, this book is also ideal for specialised graduate courses.

“Chemical engineering is the field of applied science that employs physical, chemical, and

biochemical rate processes for the betterment of humanity.” This opening sentence of Chapter 1 is the underlying paradigm of chemical engineering. Chemical Engineering: An Introduction is designed to enable the student to explore the activities in which a modern chemical engineer

explored include the design of a feedback level controller, membrane separation, hemodialysis, optimal design of a process with chemical reaction and separation, washout in a bioreactor,

kinetic and mass transfer limits in a two-phase reactor, and the use of a membrane reactor to overcome equilibrium limits on conversion. Mathematics is employed as a language at the most elementary level. Professor Morton M. Denn incorporates design meaningfully; the design and analysis problems are realistic in format and scope. Students using this text will appreciate why they need the courses that follow in the core curriculum.

MORTON M. DENN is the Albert Einstein Professor of Science and Engineering and Director of the Benjamin Levich Institute for Physico-Chemical Hydrodynamics at the City College of

New York, CUNY. Prior to joining CCNY in 1999, he was Professor of Chemical Engineering at the University of California, Berkeley, where he served as Department Chair, as well as Program Leader for Polymers and Head of Materials Chemistry in the Materials Sciences Division of

the Lawrence Berkeley National Laboratory. He previously taught chemical engineering at the University of Delaware, where he was the Allan P. Colburn Professor. Professor Denn was Editor of the AIChE Journal from 1985 to 1991 and Editor of the Journal of Rheology from 1995 to 2005. He is the recipient of a Guggenheim Fellowship; a Fulbright Lectureship; the Professional Progress, William H. Walker, Warren K. Lewis, Institute Lectureship, and Founders Awards of the American Institute of Chemical Engineers; the Chemical Engineering Lectureship of the

American Society for Engineering Education; and the Bingham Medal and Distinguished Service

Chemical Engineering An Introduction Morton Denn City College, City University of New York

Chemical Engineering: An Introduction enables students to explore the activities a modern chemical engineer is involved with, by focusing on mass and energy balances in liquid-phase processes.

Contents: Preface; 1. Introduction; 2. Basic concepts of analysis; 3. The balance equation; 4. Component mass balances; 5. Membrane separation; 6. Reacting systems; 7. Designing reactors; 8. Bioreactors and nonlinear systems; 9. Overcoming equilibrium; 10. Two-phase systems and interfacial mass transfer; 11. Equilibrium staged processes; 12. Energy balances; 13. Heat exchange; 14. Energy balances for multi-component systems; 15. Energy balances for reacting systems.

Cambridge Series in Chemical Engineering

2012 253 x 177 mm 278pp 104 b/w illus. 38 tables 87 exercises 978-1-107-01189-2 Hardback £85.00 978-1-107-66937-6 Paperback £35.00 eBook available

Awards of the Society of Rheology. He is a member of the National Academy of Engineering and the American Academy of Arts and Sciences, and he received an honorary DSc from

the University of Minnesota. His previous books are Optimization by Variational Methods;

Introduction to Chemical Engineering Analysis, coauthored with T. W. Fraser Russell; Stability of Reaction and Transport Processes; Process Fluid Mechanics; Process Modeling; and Polymer Melt Processing: Foundations in Fluid Mechanics and Heat Transfer.

Chemical Engineering AN INTRODUCTION

M O R T O N M. D E N N

Cover photo: Stellarator II. © Kim Dylla. Used with permission.

Cover design by Alice Soloway

Cambridge Series in Chemical Engineering

2011 247 x 174 mm 416pp 200 b/w illus. 4 tables 978-0-521-51599-3 Hardback

Colloidal suspensions are encountered in a multitude of natural, biological,

“Appropriately, the first book to span

and industrially relevant products and processes. Understanding what

the subject of suspension rheology

affects the flow behavior, or rheology, of colloid suspensions, and how this

is authored by Jan Mewis, a pioneer

flow behavior can be manipulated, is important for successful formulation

in the field, and Norm Wagner,

£85.00

of products such as paint, polymers, foods, and pharmaceuticals.

many of the modern frontiers.”

William B. Russel,

mathematical derivations kept to a minimum, the reader will gain a strong

Princeton University

grasp of the basic principles of colloid science and rheology. Beginning with purely hydrodynamic effects, the contributions of Brownian motion

eBook available

whose research has advanced

This book is the first devoted to the study of colloidal rheology in all its aspects. With material presented in an introductory manner, and complex

“The elegant presentation style,

and interparticle forces are covered, before the reader is guided through

focusing on the fundamental

specific problem areas, such as thixotropy and shear thickening; special

concepts, bridging engineering

classes of colloid suspensions are also treated. The techniques necessary

and physics, experiment and

for measuring colloidal suspension rheology are presented along with

theory, and paying attention to the

methods to correlate and interpret the results. An essential guide for

interplay between microstructure

academic and industrial researchers, this book is also ideal for graduate course use.

www.cambridge.org/9780521515993

Jan Mewis is Emeritus Professor of the Chemical Engineering Department at the Katholieke Universiteit Leuven. He is involved in industrial and

and rheology, reflects the vast teaching and research experience of the authors, and makes the book a much needed reference for practitioners, researchers and graduate students.”

academic research in complex fluids such as suspensions and polymer

Dimitris Vlassopoulos,

blends. Professor Mewis has lectured all over the world and has written over

IESL-FORTH, Greece

200 publications on colloid science and rheology. He was Chairman of the International Committee on Rheology and is a recipient of the Gold Medal

“Ever since I learned that Mewis and

of the British Society of Rheology and the Bingham Medal of The Society of

Wagner were preparing Colloidal

Rheology (USA).

Suspension Rheology I have been eagerly awaiting its arrival. I was

Norman J. Wagner received his Doctorate from Princeton University and

not disappointed! … The concise

is a named Professor and Chair of the Department of Chemical Engineering

review of colloidal phenomena

at the University of Delaware. He has extensive international teaching

in Chapter 1 is outstanding and

and research experience, and leads an active research group covering

the Advanced Topics in the final

fields such as rheology, complex fluids, polymers, nanotechnology, and

chapter (microrheology, electro

Dynamics and Nonlinear Control of Integrated Process Systems

particle technology. Professor Wagner has received several awards for his

and magneto-rheology and 2

research developments, has co-authored over 150 scientific publications

dimensional rheology) are a

and patents, and is on the editorial boards of five international journals. He

special treat.”

currently serves on the executive board of the Society of Rheology and the

Chris Macosko,

Neutron Scattering Society of America.

University of Minnesota & IPRIME

Mewis and Wagner Colloidal Suspension Rheology

Swinburne University of Technology, Victoria

2010 247 x 174 mm 248pp 159 b/w illus. 6 tables 978-0-521-88240-8 Hardback

www.cambridge.org/9780521168229

and G. D. Moggridge

Jan Mewis

is involved by focusing on mass and energy balances in liquid-phase processes. Applications

eBook available

Second edition E. L. Cussler University of Cambridge

Universal Biosensors Pty Ltd

2011 247 x 174 mm 452pp 76 b/w illus. 80 tables 81 exercises 978-0-521-16822-9 Paperback £40.00

Colloidal Suspension Rheology

Chemical Engineering AN INTRODUCTION

Chemical Product Design

Cambridge Series in Chemical Engineering

15

DENN

Femtosecond Biophotonics

Contents: 1. An introduction to chemical product design; 2. Needs; 3. Ideas; 4. Selection; 5. Product manufacture; 6. Commodity products; 7. Devices; 8. Molecular products; 9. Microstructures; 10. A plan for the future.

Y BLK

effect at molecular level in the lungs, and is invaluable to the many groups involved with research in this area.

MEWIS: Colloidal Suspension Rheology PPC C M

14

Colloidal Suspension Rheology Jan Mewis and Norman J. Wagner

Cover designed by Hart McLeod Ltd

Michael Baldea University of Texas, Austin

and Prodromos Daoutidis University of Minnesota

Aimed at researchers and engineers interested in analysing and controlling integrated chemical plants as well as other systems with complex interconnections (reaction networks, power grids, information networks, supply chains), this monograph combines a pedagogical style of exposition, technical rigor,

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eBooks available at www.cambridge.org/ebookstore

16

Chemical Engineering practical examples, case studies and implementation guidelines.

Cambridge Series in Chemical Engineering

2012 247 x 174 mm 270pp 115 b/w illus. 7 tables 978-0-521-19170-8 Hardback c. £75.00 Publication July 2012 www.cambridge.org/9780521191708

FORTHCOMING

Chemistry of Fossil Fuels and Biofuels Harold Schobert Pennsylvania State University

Focusing on today’s major fuel resources, this book discusses the natural processes by which they formed; their composition and properties; and the ways in which they are converted or upgraded into the forms in commercial use. It is ideal for graduate students and professionals in chemical engineering and energy technology.

Cambridge Series in Chemical Engineering

247 x 174 mm 600pp 200 b/w illus. 54 tables 978-0-521-11400-4 Hardback c. £65.00 Publication January 2013 www.cambridge.org/9780521114004

Chemical Engineering TEXTBOOK

TEXTBOOK

FORTHCOMING

FORTHCOMING

Separations of Molecules, Macromolecules and Particles

Chemical, Biological and Materials Engineering Thermodynamics

Principles, Phenomena and Processes Kamalesh Sirkar New Jersey Institute of Technology

Written for an advanced separation process course in chemical engineering, this textbook provides students with a basic understanding of molecular, macromolecular and particle separation techniques. With a wide range of industrial examples, worked through problems, homework sets, and a solutions manual for instructor use, this is the complete textbook package.

Contents: Introduction to the book; 1. Description of separation in a closed system; 2. Description of separation in open separators; 3. Physicochemical basis for separation; 4. Separation in a closed vessel; 5. Effect of chemical reaction on separation; 6. Open separators: bulk flow parallel to force and continuous stirred tank separators; 7. Separation in bulk flow of feed-containing phase perpendicular to the direction of the force; 8. Bulk flow of two phases/regions perpendicular to the direction(s) of the force(s); 9. Cascades; 10. Energy required for separation; 11. Common separation sequences.

Cambridge Series in Chemical Engineering

246 x 189 mm 1000pp 450 b/w illus. 40 tables 300 exercises 978-0-521-89573-6 Hardback c. £55.00 Publication January 2013 www.cambridge.org/9780521895736

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methods. The book is also focused on the solutions of representative problems. ‘… provides a solid fundamental and detailed description of mathematical and physical principles of fluid mechanics and mass transfer problems, pointing out the most important practical applications … extremely well written … very easily readable …

I believe that the concepts presented in this book will deeply stimulate new research in fluid mechanics and heat and mass transfer.’

Ioan Pop, Zentralblatt MATH

Juan J. de Pablo University of Wisconsin, Madison

Nicholas L. Abbott University of Wisconsin, Madison

and Jay P. Schieber Center for Molecular Study of Condensed Soft Matter

Cambridge Series in Chemical Engineering

Integrates classical, statistical and molecular thermodynamics, for instructors teaching a modern thermodynamics course.

2010 253 x 215 mm 934pp 100 b/w illus. 4 tables 227 exercises 978-0-521-17908-9 Paperback £60.00 eBook available

Cambridge Series in Chemical Engineering

www.cambridge.org/9780521179089

247 x 174 mm 650pp 978-0-521-76562-6 Hardback c. £60.00 Publication January 2013 www.cambridge.org/9780521765626

PUBLISHED IN PARTNERSHIP WITH THE MATERIALS RESEARCH SOCIETY

NEW IN PAPERBACK

HIGHLIGHT

TEXTBOOK

TEXTBOOK

Advanced Transport Phenomena

Fundamentals of Materials for Energy and Environmental Sustainability

Fluid Mechanics and Convective Transport Processes L. Gary Leal

Edited by David S. Ginley

University of California, Santa Barbara

Advanced Transport Phenomena is ideal as a graduate textbook. It contains a detailed discussion of modern analytic methods for the solution of fluid mechanics and heat and mass transfer problems, focusing on approximations based upon scaling and asymptotic

National Renewable Energy Laboratory, Golden, Colorado

and David Cahen Weizmann Institute of Science, Israel

How will we meet rising energy demands? What are our options? Are there viable long-term solutions for the future? Whether you are a student taking an energy course or a newcomer to the field, using this textbook you will understand the critical relationships

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17

Chemical Engineering between the environment, energy and sustainability.

Ian S. F. Jones University of Sydney

This book gives a concise review of current knowledge required for engineers to develop strategies to help us manage and adapt to climate change.

It is written without technical jargon so as to be accessible to a wide range of students and policymakers.

www.cambridge.org/9780521516020

Texas State University, San Marcos

University of Minnesota

Written for researchers and practitioners, this book provides a complete introduction to the science, engineering, and commercial applications of polymerclay nanocomposites. Physical and mechanical properties are explained, with chapters on thermodynamics and kinetics, barrier properties, and flame retardancy. Coverage of fabrication methods and material characterisation make this the must-have reference.

2011 247 x 174 mm 194pp 36 b/w illus. 1 table 978-0-521-87643-8 Hardback

2011 228 x 152 mm 328pp 79 b/w illus. 6 tables 106 exercises 978-0-521-76561-9 Hardback £50.00 www.cambridge.org/9780521765619

£70.00

eBook available

www.cambridge.org/9780521876438

Polymer Physics Applications to Molecular Association and Thermoreversible Gelation Fumihiko Tanaka Kyoto University, Japan

Maintaining a balance between theoretical descriptions and practical applications, Fumihiko Tanaka provides an up-to-date, unified treatment of polymer association and thermoreversible gelation. Fundamental laws of polymer physics, recent developments are explored, along with relevant case studies. This book will appeal to both researchers and students.

2011 247 x 174 mm 404pp 185 b/w illus. 8 tables 978-0-521-86429-9 Hardback

Presenting the principles of thermodynamics from a microscopic point of view, this book provides engineers with the knowledge they need to solve engineering challenges at the molecular level. Featuring many worked examples and over 100 end-of-chapter exercises, it is ideal for use in the classroom as well as for self-study.

£80.00

eBook available

Computational Fluid Dynamics for Engineers

£65.00

eBook available

www.cambridge.org/9781107018952 statistical Thermodynamics and stochastic Kinetics

TEXTBOOK

Presenting the key principles of thermodynamics from a microscopic point of view, this

Thermodynamics Sanford Klein

book provides engineers with the knowledge they need to apply thermodynamics and solve engineering challenges at the molecular level. it clearly explains the concepts of entropy and free energy, emphasizing key ideas used in equilibrium applications, whilst stochastic process, such as stochastic reaction kinetics, are also covered. it provides a classical microscopic interpretation of thermodynamic properties, which is key for engineers, rather than focussing on more esoteric concepts of statis-

University of Wisconsin, Madison

and Gregory Nellis

tical mechanics and quantum mechanics.

Coverage of molecular dynamics and Monte Carlo simulations as natural extensions of the theoretical treatment of statistical thermo-

Y ia n n is n. K a z n es s is is a Professor in the Department of Chemical engineering and Materials science at the University of Minnesota, where he has taught statistical thermodynamics since 2001.

He has received several awards and recognitions, including the Fulbright award, the Us national science Foundation CaReeR award, the 3M nonTenured Faculty award, the iBM Young Faculty award, the aiChe Computers and systems Technology Division Outstanding Young Researcher award, and the University of Minnesota College of science and engineering Charles Bowers Faculty Teaching award.

dynamics is also included, teaching readers how to use computer simulations, and thus enabling them to understand and engineer the microcosm. Featuring many worked examples and over 100 end-of-chapter exercises, it is

University of Wisconsin, Madison

ideal for use in the classroom as well as for Cover illustration: the phase space

self-study.

of a microcanonical ensemble.

Yiannis n. Kaznessis

statistical Thermodynamics and

stochastic Kinetics an introduction for engineers

Provides students and practitioners with the concepts, tools and experience needed to solve practical energy problems by integrating computer tools with thermodynamic concepts. www.cambridge.org/kaznessis

• FORTRAN and MATLAB codes

2012 253 x 215 mm 1100pp 612 b/w illus. 72 tables 289 exercises 978-0-521-19570-6 Hardback £79.00 eBook available

www.cambridge.org/9780521195706

Bengt Andersson Chalmers University of Technology, Gothenberg

Ronnie Andersson Chalmers University of Technology, Gothenberg

Love Håkansson Engineering Data Resources (EDR), Norway

TTitle HERMODYNAMICS

eBook available

An Introduction for Engineers Yiannis N. Kaznessis

2011 247 x 174 mm 202pp 76 b/w illus. 11 tables 978-1-107-01895-2 Hardback

KLEIN NELLIS

2011 247 x 174 mm 184pp 42 b/w illus. 16 tables 18 exercises 978-0-521-51602-0 Hardback £55.00 978-0-521-73159-1 Paperback £24.99

Gary W. Beall and Clois E. Powell

managers requiring the basics in order to negotiate with consulting companies.

C O V e R D e s i G n : s U e WaT s O n

Engineering Strategies for Greenhouse Gas Mitigation

Statistical Thermodynamics and Stochastic Kinetics

statistical Thermodynamics and stochastic Kinetics

2012 276 x 219 mm 772pp 450 colour illus. 80 tables 978-1-107-00023-0 Hardback £65.00 www.cambridge.org/9781107000230

Fundamentals of Polymer-Clay Nanocomposites

19

Kaznessis

Contents: Part I. Energy and the Environment; Part II. Nonrenewable Energy Sources; Part III. Renewable Energy Sources; Part IV. Transportation; Part V. Energy Efficiency; Part VI. Energy Storage, High-Penetration Renewables and Grid Stabilization.

Chemical Engineering

Kaznessis: statistical Thermodynamics and stochastic Kinetics PPC C M Y BLK

18

THERMODYNAMICS Sanford Klein Gregory Nellis

Mikael Mortensen Norwegian Defence Research Establishment (FFI)

Rahman Sudiyo Universitas Gadjah Mada, Indonesia

and Berend van Wachem Imperial College London

An introduction to a fast growing discipline, this book delivers the knowledge required to use CFD successfully in a wide range of engineering applications. Ideal for engineers wanting to enter the field or widen their understanding and project

www.cambridge.org/9780521864299

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Order online at www.cambridge.org/chembio

20

Chemical Engineering TEXTBOOK

Convective Heat and Mass Transfer S. Mostafa Ghiaasiaan Georgia Institute of Technology

Chemical Engineering Fluid Dynamics and Transport of Droplets and Sprays Second edition William A. Sirignano

Spouted and Spout-Fluid Beds

NEW IN PAPERBACK

Fundamentals and Applications Edited by Norman Epstein and John R. Grace

Statistical Thermodynamics

This book is ideal for a graduate course on convection heat and mass transfer.

It treats well-established theory and practice but is also enriched by its coverage of modern areas such as flow in microchannels and computational fluid dynamics-based design and analysis methods. It includes numerous examples and exercises.

University of California, Irvine

University of British Columbia, Vancouver

This book explores the theoretical and computational aspects of the fluid dynamics and transport of sprays and droplets. Two new chapters introduce liquid-film vaporisation as an alternative to sprays for miniature applications and a review of liquid-stream distortion and break-up theory.

2011 253 x 215 mm 548pp 140 b/w illus. 34 tables 147 exercises 978-1-107-00350-7 Hardback £90.00

2010 253 x 215 mm 480pp 161 b/w illus. 10 tables 978-0-521-88489-1 Hardback

Comparing and combining data from internationally renowned research groups, this is the only up-to-date book on spouted bed research and practice.

Guiding the reader through new developments, insights and models, this is a valuable resource for chemical and mechanical engineers in research and industry.

eBook available

eBook available

2010 247 x 174 mm 360pp 100 b/w illus. 40 tables 978-0-521-51797-3 Hardback

www.cambridge.org/9781107003507

www.cambridge.org/9780521884891

eBook available

£70.00

£80.00

www.cambridge.org/9780521517973

Introductory Fluid Mechanics

Hydrodynamic Instabilities

Joseph Katz

François Charru

San Diego State University

Designed as a first course on this subject, Katz introduces the principles of fluid mechanics, and at the same time it provides sufficient analytical background for more specific courses in this field.

The reader will understand the basic principles and have the ability to use these skills for engineering design.

2010 253 x 215 mm 456pp 264 b/w illus. 4 tables 461 exercises 978-0-521-19245-3 Hardback £80.00 eBook available

www.cambridge.org/9780521192453

An Introduction to Fluid Mechanics

Université Paul Sabatier (Toulouse III)

Faith Morrison

Translated by Patricia de ForcrandMillard

Michigan Technological University

Written for any student, researcher or practitioner working in the area, this modern introduction brings this mathematical subject to life by emphasising the physical mechanisms involved. The book includes numerous experimental studies as well as over 150 exercises and references to video material.

Cambridge Texts in Applied Mathematics, 37

2011 247 x 174 mm 410pp 200 b/w illus. 165 exercises 978-0-521-76926-6 Hardback 978-0-521-14351-6 Paperback

£75.00 £40.00

TEXTBOOK

Fundamentals and Applications Normand M. Laurendeau Purdue University, Indiana

This popular 2006 textbook discusses the fundamentals and applications of statistical thermodynamics for beginning graduate students in the physical and engineering sciences. It features a step-by-step development of the subject assuming that the reader has no previous exposure to statistics, quantum mechanics or spectroscopy. Numerous examples and prompted homework problems enrich the text.

2011 253 x 215 mm 466pp 96 b/w illus. 64 tables 117 exercises 978-0-521-15419-2 Paperback £47.00 eBook available

www.cambridge.org/9780521154192

This is a modern and elegant introduction to engineering fluid mechanics enriched with numerous examples, exercises, and applications.

Based on Faith Morrison’s vision that flows are both beautiful and complex, it delves deeply into the mathematical analysis of flows on the basis that such analysis is essential to designing and optimizing modern systems and devices.

2012 253 x 177 mm 800pp 520 b/w illus. 40 tables 500 exercises 978-1-107-00353-8 Hardback c. £75.00 Publication September 2012 www.cambridge.org/9781107003538

eBook available

www.cambridge.org/9780521769266

eBooks available at www.cambridge.org/ebookstore

eBooks available at www.cambridge.org/ebookstore

21

22

Chemical Engineering

NEW IN PAPERBACK

TEXTBOOK

TEXTBOOK

Gasoline, Diesel and Ethanol Biofuels from Grasses and Plants

Combustion Physics Chung K. Law Princeton University, New Jersey

A graduate text on the fundamentals of chemically reacting flows for students of applied physics, aerospace, mechanical, and chemical engineering.

Its distinguishing feature is the rigorous, yet approachable, presentation. It provides a solid foundation for a graduate program in combustion and a starting point for research on new projects.

‘Combustion Physics is an excellent text that is comprehensive in coverage, rigorous yet expeditious in the analytical developments, insightful in the physical descriptions, and above all, very readable. It is not only an invaluable reference for combustion researchers, but its emphasis on clarity and logical presentation makes it particularly attractive for classroom adoption for a graduate course on combustion in aerospace, mechanical, or chemical engineering and the physical sciences … The author is to be congratulated for having made this valuable, lasting contribution to combustion literature and education.’

AIAA Journal 2010 253 x 215 mm 742pp 16 tables 104 exercises 978-0-521-15421-5 Paperback

Order online now at www.cambridge.org/chembio

Ram B. Gupta Auburn University, Alabama

Order by phone: +44 (0)1223 326050

and Ayhan Demirbas Sirnak University

The first-generation biofuels – ethanol from sugar or corn and biodiesel from vegetable oils – created to replace petroleum are already in the market, with limited success. Alternatives to petroleum must be technically feasible, economically competitive, environmentally acceptable, and easily available. This textbook introduces readers to second-generation biofuels from non-food biomass.

2010 253 x 215 mm 246pp 104 b/w illus. 83 tables 978-0-521-76399-8 Hardback

£47.00

eBook available

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CAMBRIDGE TEXTS IN CAMBRIDGE TEXTS IN BIOMEDICAL ENGINEERING

rs to the field.

Series Editors Professor W. Mark Saltzman, Yale University Professor Shu Chien, University of California, San Diego

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“The authors have written a detailed yet easy-to-read book that can be used by materials scientists and biomedical engineers… rich in practical examples of biomaterials used in permanent implants currently on the market.”

Stephen Spiegelberg, Cambridge Polymer Group, Inc., MA, USA “…provides a much needed comprehensive resource for engineers, physicians, and implant designers at every level of training and practice.”

Michael Ries, University of California, San Francisco

Mechanics of Biomaterials

medical devices sues and presents

“Mechanics of Biomaterials is the textbook I have been waiting for. … an outstanding text and reference book that should be required reading for all who aspire to design, develop and evaluate medical devices.”

Jeremy L. Gilbert, Syracuse University

Pruitt and Chakravartula

concepts for ained text provides

nd Case Studies – it

BIOMEDICAL ENGINEERING

Mechanics of

Biomaterials Fundamental Principles for Implant Design

Lisa A. Pruitt and Ayyana M. Chakravartula

PUBLISHED IN PARTNERSHIP WITH THE MATERIALS RESEARCH SOCIETY

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Printed in the United Kingdom on elemental-chlorine-free paper from sustainable forests. 2012.