CHOOSE TAUROLOCK™-U25.000: A SAFE & EFFECTIVE UROKINASE LOCK SOLUTION TauroLock™-U25.000 is a catheter locking solution combining taurolidine, an antimicrobial substance and 4% citrate as an anticoagulant, with urokinase (25.000 IU), a thrombolytic compound. TauroLock™-U25.000 is shown to prevent catheter dysfunction and patency issues if used to lock lines prophylactically e.g. on a weekly basis. 1 Protects your patients | Prevents blocked lines | Prevents infection 1 | Prevents biofilm formation in your lines 2
TauroLock™-U25.000 contains the antimicrobial substance Taurolidine, 4% Citrate and Urokinase (25.000 IU).
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Outcomes for infection: IRR (95% CI) 0.25 (0.09-0.63) | Outcomes for catheter dysfunction: IRR (95% CI) 0.42 (0.34 - 0.51) - Winnicki, W., Herkner, H., Lorenz, M., Handisurya, A. (2017). Taurolidine-based catheter lock regimen significally reduces overall costs, infection and dysfunction rates of tunneled hermodialysis catheters. Kidney International 93(3).
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Jimenez Hernandez, M., Soranio, A., Filella, X., Calvo, M., Coll, F., Rebled, J.M., Poch, E., Graterol, F., Compte, M.T., Maduell, F., Fontsere, N. (2020). Impact of locking solutions on conditioning biofilm formation in tunneled haemodialysis catheters and inflammatory response activasion. The Journalist of Vascular Access.
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