BusinessMirror May 09, 2021

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ROTARY CLUB OF MANILA JOURNALISM AWARDS

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A broader look at today’s business n

Sunday, May 9, 2021 Vol. 16 No. 207

EJAP JOURNALISM AWARDS

BUSINESS NEWS SOURCE OF THE YEAR (2017, 2018)

DEPARTMENT OF SCIENCE AND TECHNOLOGY

2018 BANTOG MEDIA AWARDS

PHILIPPINE STATISTICS AUTHORITY

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IVERMECTIN:

ALEXEY NOVIKOV | DREAMSTIME.COM

Silver bullet or snake oil?

Debates continue to rage on the use and efficacy of a controversial drug as Covid-19 continues to do its worst in the PHL and the rest of the world.

A

By Jovee Marie N. Dela Cruz

S the country struggles mightily to tame a surge in Covid-19 cases, the cheap anti-parasitic drug Ivermectin has emerged as the “wonder drug” that may potentially end the contagion.

Though touted by some as the “silver bullet,” it may not be yet, however, the magical solution everyone is looking for, as evidence for its efficacy against the deadly virus remains thin, according to regulators. That evidence may be bolstered by the outcome of local clinical trials scheduled this month. But till then, the verdict is still out, though the word of mouth continues to spread the good news about Ivermectin. In the House of Representatives, hearings have been conducted to urge government regulators to “keep an open mind” on Ivermectin, a drug being used in many countries to prevent and treat the deadly virus. From the experts’ collective

testimony, Anakalusugan Party-list Rep. Mike Defensor and Sagip Rep. Rodante Marcoleta said Ivermectin had been widely used to treat a variety of human parasites since its introduction in 1981, and since then is being taken along with vitamins C and D, melatonin, zinc, among others, including steroids for elderly and asthmatic patients. They also said Ivermectin has undergone in vitro studies effectively killing the Covid-19 virus and was found to cure bacterial infection for pneumonia.

Debates on efficacy

CITING Frontline Covid-19 Critical Care Alliance President Dr. Pierre Kory, et al.’s scientific medical paper on the efficacy of Iver-

PESO EXCHANGE RATES n US 47.9790

mectin, which is now published in the American Journal of Therapeutics, Marcoleta asserted that Ivermectin is effective in treating Covid-19. “This study concludes that meta-analyses based on 18 randomized controlled treatments of Ivermectin in Covid-19 have found large, statistically significant reduction in mortality, time to clinical recovery and time to viral clearance. Also, results from various controlled prophylaxis trials showed significantly reduced risks of contracting Covid-19 with regular use of Ivermectin,” Marcoleta added. Defensor said they are pushing for Ivermectin as a cure because the poor needed to gain access to an inexpensive therapeutic to fight Covid-19 “because the drugs the Department of Health (DOH) and the Philippine Food and Drug Administration (FDA) are promoting are for the rich.” His exhibit A: “Remdesivir, for instance, costs from P12,000 to P48,000 per vial, and you need two vials a day. On the other hand, Ivermectin costs only P35 per tablet, and only one tablet is needed daily. The DOH and FDA are allowing the use of Remdesivir, while cracking down on Ivermectin. Their bias is for the rich and against the poor,”

DEFENSOR: “The drugs the Department of Health and the Philippine Food and Drug Administration are promoting are for the rich.”

Defensor alleged. Nonetheless, the DOH and the FDA reiterated that the agencies do not recommend the use of Ivermectin for the treatment of Covid-19 due to insufficient scientific evidence. FDA Director General Eric Domingo told lawmakers that any use of Ivermectin for the prevention or treatment of Covid 19 should be avoided as the benefits and safety for this purpose has not yet been established. “We have said this many times before and we will say it again. We do not recommend the use of Ivermectin for the prevention and treatment of Covid-19 as

DOMINGO: “We have said this many times before and we will say it again. We do not recommend the use of Ivermectin for the prevention and treatment of Covid-19 as the benefits of this anti-parasitic drug for this purpose have not been established.”

the benefits of this anti-parasitic drug for this purpose have not been established. President Rodrigo Duterte has also ordered DOST [Department of Science and Technology] to conduct a clinical trial to test the efficacy of Ivermectin against Covid-19. Let’s wait for the results,” Domingo said in a news statement. In a briefing on April 15, Domingo told President Duterte that high doses of Ivermectin may cause pulmonary problems, neurologic and brain damage. Citing studies done in Australia, Domingo added that, “Although

it is a safe medicine and has been used largely for the past 40 years for animals and humans, there are also side effects when the doses are too high and patients may get a fever and liver damage.” Currently, the Philippines FDA said the registered Ivermectin products in the country for human use are in topical formulations under prescription use only, saying this is used for the treatment of external parasites such as head lice and skin conditions such as rosacea. The FDA also said the registered oral and intravenous preparations of Ivermectin are veterinary products which are approved for use in animals for the prevention of heartworm disease and treatment of internal and external parasites in certain animal species. As of April 27, the FDA said, five hospitals have already secured compassionate special permits (CSP) to use Ivermectin on Covid-19 patients. Among the more notable personalities reported to be using it as prophylactic are former Senate President Juan Ponce Enrile and the incumbent Senate President Vicente Sotto III. Also, Defensor said, “everyone from the Cabinet, doctors, police Continued on A2

n JAPAN 0.4399 n UK 66.6524 n HK 6.1766 n CHINA 7.4236 n SINGAPORE 35.9960 n AUSTRALIA 37.3277 n EU 57.8819 n SAUDI ARABIA 12.7948

Source: BSP (May 7, 2021)


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