School of Pharmacy and Pharmaceutical Sciences 2023-24 Annual Report

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SCHOOL OF PHARMACY AND P H ARMACE U T I C A L SC I E N CES

2023-2024 ANNUAL REPORT

2023-2024 ANNUAL REPORT: DEAN’S MESSAGE

Binghamton University’s School of Pharmacy and Pharmaceutical Sciences has achieved significant milestones and celebrated remarkable successes over the past year. It is with great pride that I reflect on the outstanding contributions of our faculty, staff, and students, whose dedication continues to elevate our school and its impact on the profession. A few highlights from the past year include:

• The successful graduation of our first cohort of pharmacy technicians, addressing the critical shortage of skilled professionals in the Greater Binghamton area.

• A record-breaking 84 co-curricular events, offering unparalleled opportunities for professional growth and leadership development.

• Exceptional post-graduate achievements, with students securing prestigious industry fellowships, PGY1 residencies, and PGY2 residencies.

• Faculty members earning regional and national recognition for their excellence in education, research, and clinical practice through awards from organizations such as APhA, ACCP, and AACP.

• A notable distinction of three faculty members being ranked among the Top 2% of researchers worldwide in their fields, as recognized by the Stanford University Study in 2023.

This annual report provides a comprehensive overview of our faculty’s impactful research presentations, publications, and funding achievements, highlighting the innovation and dedication that define our school.

We are proud of these accomplishments and remain steadfast in our commitment to advancing pharmacy education, fostering innovation, and nurturing the next generation of pharmacy professionals. Together, we are building a future of excellence and impact.

Sincerely,

Platform Presentation: Hoffman E. Plenary Lecture “The venture philanthropy model of drug Development.” DUPHAT. Dubai, United Arab Emirates. Jan. 9, 2024.

Platform Presentation: Hoffman E. Workshop “The increased emphasis of competent authorities on pre-clinical efficacy studies in rare disease.” DUPHAT. Dubai, United Arab Emirates. Jan. 11, 2024.

Platform Presentation: Hoffman E. “Evolution of Diagnosis and Dystrophin.” Neuromuscular Centers of Excellence Health Care Professionals. Parent Project Muscular Dystrophy. Coral Gables, Fla. Jan 17, 2024.

Platform Presentation: Hoffman E. JLABS, Public workshop on vamorolone development. Children’s National Medical Center. Silver Spring, Md. Mar. 27, 2024.

Platform Presentation: Hoffman E. “Vamorolone: How a Public-Private Partnership Succeeded in Bringing a Rare Disease Drug to Market.” Rare Disease Day. National Institutes of Health. Bethesda, Md. Mar. 29, 2024.

Gordon Huang, P4 Student

Rachel Klosko as mentor

Poster Presentation: Huang G, Klosko R, Krummenacker B, Major J, Reiver M. “Evaluation of major inpatient statin-drug interactions in inpatient older adults prescribed simvastatin compared to all other statins.” American Society of Health-System Pharmacists (ASHP) Midyear Clinical Meeting & Exhibition. Anaheim, Calif. Dec. 4, 2023.

Keith Hughes, PharmD Class of ‘23

Poster Presentation: Hughes KM, Campbell J, Carswell J, Williams K. “Pharmacist-Led Intervention Study for Improving Medication Adherence and Health Outcomes in a Rural Population of Patients with COPD.” American Society of Health-System Pharmacists (ASHP) Midyear Clinical Meeting & Exhibition. Anaheim, Calif. Dec. 6, 2023.

Eshraq Islam, P4 Student

Poster Presentation: Islam E, Midence L, Heuser W, Barrera R. “A Retrospective Feasibility Study Evaluating Bayesian Therapeutic Drug Monitoring

Software at Predicting Phenobarbital Levels in the Critically Ill Population.” American Society of Health-System Pharmacists (ASHP) Midyear Clinical Meeting & Exhibition. Anaheim, Calif. Dec. 4, 2023.

Rachel Klosko, PharmD

Platform Presentation: McGinley J M, Doughty B, Rouhana N, Klosko R, Seward S. “Caring for people with intellectual and developmental disabilities: Findings from a community-engaged, interprofessional education learning retreat.” Nexus Summit. Virtual. September 2023.

Platform Presentation: Saseen J, Klosko R. “Evidence-Based Updates on LDL-C Lowering: Statins and Beyond.” American College of Clinical Pharmacy (ACCP) Cardiology Practice and Research Network (PRN). National Webinar. October 2023.

Emily Leppien, PharmD

Platform Presentation: Leppien EE. “Talking Things Pharmacists Need to Know About Urine Drug Monitoring.”American Pharmacists Association Locked on Pharmacy. Podcast. July 31, 2023.

Platform Presentation: Leppien EE. “Principles of Proper Pain Management.” Continuing education, 1.5 credit hours. American Pharmacists Association Initiating Buprenorphine Certificate Training Program. Virtual. Oct. 19, 2023.

Platform Presentation: Leppien EE. “Utility of the FAERS Database for Clinical Practice and Research.” Continuing education, 1 credit hour. Geisinger Center for Pharmacy Innovation and Outcomes. Virtual. Dec. 15, 2023.

Wesley Kufel, PharmD

Platform Presentation: Kufel WD. “Antimicrobial Stewardship.” Department of Medicine Grand Rounds, SUNY Upstate Medical University. Syracuse, N.Y. Aug. 14, 2023.

Platform Presentation: Kufel WD. “Putting ‘PEP’ to the Step: Comprehensive Evaluation of Tick-Bite Post-Exposure Prophylaxis.” Lyme and Tick-Borne Disease Summit. Syracuse, N.Y. Sept. 29, 2023.

Platform Presentation: Kufel WD, Blumenthal KG, Calvano TP, Jones BM. “What About Non-

Beta-Lactam Allergies? Case Discussion Including Management Strategies.” IDWeek 2023. Boston, Mass. Oct. 13, 2023.

Platform Presentation (Moderator): Kufel WD, Hobbs ALV. “Surveillance for New Agents.” IDWeek 2023, Boston, Mass. Oct. 13, 2023.

Platform Presentation: Kufel WD. “Up and Out! Antimicrobial Stewardship in Transitions of Care.” Premier Antimicrobial Stewardship Forum. Virtual. Dec. 12, 2023.

Poster Presentation: Wu M, Kufel WD, Riddell SW, Steele JM, Asiago-Reddy EA. “Duration of Methicillin-Resistant Staphylococcus aureus (MRSA) Nares PCR Positivity While Receiving Highly Active Anti-Staphylococcal Drugs.” IDWeek 2023. Boston, Mass. Oct. 12, 2023.

Poster Presentation: Kufel WD, Mastro KA, Blaine BE. “Impact of Standardized Patient Simulation on Pharmacy Students’ Confidence and Perceptions in Community-Acquired Bacterial Meningitis Management.” IDWeek 2023. Boston, Mass. Oct. 12, 2023.

Poster Presentation: Shaw M, Derrick C, Pizzuti M, Justo JA, Frens JJ, Kufel WD, de Lima Corvino D, Krekel T, Kabbani S, Brock J, Derringer J, La Hoz RM, Kinn PM, Diaz B, Bookstaver PB. “Evaluating Dalbavancin Suppression Therapy in Patients at High Risk for Recurrent Infections.” IDWeek 2023. Boston, Mass. Oct. 13, 2023.

Poster Presentation: Shields RK, Abbo LM, Ackley R, Aitken SL, Albrecht B, Babiker A, Cifuentes R, Claeys KC, DeSear K, Gallagher JC, Gregory E, Heil EL, Hickey C, Klatt M, Kline EG, Kubat RC, Kufel WD, Lee JG, Lim A, Lingg T, MacDougall C, Mathers A, McCreary EK, Moore WJ, Olson S, Oxer J, Pearson JC, Pham C, Polk C, Satlin MJ, Satola SW, Shah S, Solanki YB, Tamma P, Vega A, Veena V, Veve MP, Wangchinda W, Witt LS, Wu J, Pogue JM. “A Multicenter, Observational Study to Compare the Effectiveness of Ceftazidime-Avibactam Versus Ceftolozane-Tazobactam for Multidrug Resistant Pseudomonas aeruginosa Infections in the United State (CACTUS).” IDWeek 2023. Boston, Mass. Oct. 13, 2023.

Poster Presentation: Kunz-Coyne AJ, Lucas K, Shald E, Cabanilla MG, Yost C, VanDorf S, Slaton C, Kufel WD, Truong J, Andrade JA, Cerenzio J, Biagi M, Todd M, White B, Sassine J, Hayes JE, Witucki P, Orzol C, Eshaya M, Bleick C, Caniff KE, Veve MP, Rybak MJ. “Early Administration of Ceftazidime-Avibactam for Carbapenem-Resistant Enterobacterales is Associated with Improved Clinical Success.” IDWeek 2023. Boston, Mass. Oct. 13, 2023.

Poster Presentation: Kufel WD, Ali M, Spinler SA. “Evaluation of a Doctor of Pharmacy (PharmD) Capstone Research Project Experience.” AACP 2023 Annual Meeting. Dallas, Tex. Nov. 13, 2023.

Poster Presentation: Bookstaver PB, Barfield RK, Chahine E, Eiland L, Douglass Smith M, Covington E, Eudaley S, Hudson J, Hudspeth B, Kufel WD, Stover K. “Characterizing Full-Time Pharmacy Practice Faculty Engagement in Manuscript Peer Review: A Prospective Study.” American College of Clinical Pharmacy (ACCP) 2023 Annual Meeting. Dallas, Tex. Nov. 13, 2023.

Poster Presentation: Lam H, Parsels KA, Steele JM, Kufel WD, Andrew RM, Miller CD, Darko W, Seabury RW. “Implementation of the PEN-FAST Clinical Decision Tool to De-Label Penicillin Allergies: A Pharmacy Resident Driven Pilot Program.” Vizient Meeting. Anaheim, Calif. Dec. 2, 2023.

Mei Li, P4 Student

Wes Kufel as mentor

Poster Presentation: Li M, Cosler LE, Harausz EP, Myers CE, Kufel WD. “Methenamine for Urinary Tract Infection Prophylaxis: A Systematic Review.” New York State American College of Clinical Pharmacy (NYS-ACCP) Clinical Meeting. Binghamton University, School of Pharmacy and Pharmaceutical Sciences. Johnson City, N.Y. Sep. 30, 2023.

Yanyan Li, PhD

Platform Presentation: Li, Y. “Nanoscale exosomes from broccoli sprouts improve the targeted delivery and efficacy of bioactives against inflammatory bowel disease.” USDA PD Meeting. Purdue University. West Lafayette, IN. May 23-24, 2024.

Sarah Lynch, PharmD

Platform Presentation: Slazak EM, Lynch SE. “SelfCare Therapeutics/Nonprescription Medicine SIG Networking Session.” American Association of Colleges of Pharmacy (AACP) Annual Meeting. Aurora, Colo. July 24, 2023.

Platform Presentation: Cieri-Hutcherson N, Lynch SE. “Pharmacist Provision of Contraception and the Evolution of the Pharmacist’s Role in Reproductive Healthcare.” Continuing education, 1 credit hour. New York State American College of Clinical Pharmacy (NYS-ACCP) Clinical Meeting. Binghamton University, School of Pharmacy and Pharmaceutical Sciences. Johnson City, N.Y. Sep. 30, 2023.

Platform Presentation: Patel J, Anderson L, Vernon V, Lynch SE. “Women’s Health PRN and Community-Based PRN Focus Session — Navigating the Dynamic Landscape of Pregnancy Termination in America.” Continuing education, 1.5 credit hours. 2023 American College of Clinical Pharmacy (ACCP) Annual Meeting. Dallas, Tex. Nov. 11, 2023.

David Mastro, PharmD Class of ‘23

Platform Presentation: Mastro D. “Resident Hot Topics: A Review of the Role of Tranexamic Acid in Critically Ill Adult Trauma Patients.” Continuing education, 1 credit hour. New York State American College of Clinical Pharmacy (NYS-ACCP) Clinical Meeting. Binghamton University, School of Pharmacy and Pharmaceutical Sciences. Johnson City, N.Y. Sep. 30, 2023.

Melissa Morales, PhD

Platform Presentation: Morales M. “Blocking the interferon signature to improve muscle weakness in a mouse model of myositis.” The Myositis Association Annual Patient Conference. San Diego, Calif. Sep. 8, 2023.

Platform Presentation: Morales M. “Targeting the innate immune system to improve gene therapy in mdx mice.” MDA Clinical & Scientific Conference. Orlando, FL. March 5, 2024.

Kenneth McCall, PharmD

Poster Presentation: McCall K, Doughty B, Piper BJ, Naik H, Bange S, Leppien EE. “First generation antipsychotic-associated serious

adverse events in women: an analysis of a national pharmacoepidemiologic database.” New York State American College of Clinical Pharmacy (NYS-ACCP) Clinical Meeting. Binghamton University, School of Pharmacy and Pharmaceutical Sciences. Johnson City, NY. Sep. 30, 2023.

Poster Presentation: McCall K, Hennig KR, Abe ZT, Dattler DN, Hurd KL, Portnoy SL, Zagoria ZJ. “Rising Cases of Drug-Induced Pulmonary Fibrosis: Analysis of the Food and Drug Administration Adverse Event Reporting System (FAERS) Database, 2000-2022” NYS ACCP Annual Meeting. Binghamton, NY. Sep. 30, 2023

Platform Presentation: McCall K. “Recent Incidents of Counterfeit Medicines in the Supply Chain and DSCSA Training for Pharmacy Professionals.” Continuing education, 1 credit hour. New Jersey Pharmacists Association (NJPhA) 153rd Annual Meeting & Convention – Pharmacists Protectors of Public Health. Princeton, N.J. Oct. 28, 2023.

Poster Presentation: McCall K, Hennig KR, Abe ZT, Dattler DN, Hurd KL, Portnoy SL, Zagoria ZJ. “Rising Cases of Drug-Induced Pulmonary Fibrosis: Analysis of the Food and Drug Administration Adverse Event Reporting System (FAERS) Database, 2000-2022.” New York State American College of Clinical Pharmacy (NYS-ACCP) Clinical Meeting. Binghamton University, School of Pharmacy and Pharmaceutical Sciences. Johnson City, N.Y. Sep. 30, 2023; and American Society of Health-System Pharmacists (ASHP) Midyear Clinical Meeting & Exhibition. Anaheim, Calif. Dec. 4, 2023.

Platform Presentation: McCall, K. “Recent Incidents of Counterfeit Medicines in the Supply Chain and DSCSA Training for Pharmacy Professionals.” Delaware Pharmacist Society Annual Meeting. Newark, DE. April, 2024.

Platform Presentation: McCall K. “Recent Incidents of Counterfeit Medicines in the Supply Chain and DSCSA Training for Pharmacy Professionals.” Maine Pharmacy Association Annual Meeting. Freeport, ME. May, 2024.

Luis Midence, MPH, P4 Student

Leon Cosler as mentor

Poster Presentation: Midence L, Hayes JJ, Gondeck JT, Moy K, Chen MH, Hogan JD, Cosler LE. “The Influence of State Restrictions on Opioid Prescribing: 2006 – 2018.” New York State American College of Clinical Pharmacy (NYS-ACCP) Clinical Meeting. Binghamton University, School of Pharmacy and Pharmaceutical Sciences. Johnson City, N.Y. Sep. 30, 2023; and American Society of Health-System Pharmacists (ASHP) Midyear Clinical Meeting & Exhibition. Anaheim, Calif. Dec. 4, 2023.

Kanneboyina Nagaraju, PhD

Platform Presentation: Nagaraju K. “Innate immune responses to AAV mediated micro dystrophin gene therapy.” NIH Workshop to Address Emerging AAVrelated Toxicities. Bethesda, MD. July 26-27, 2023

Edisson Ospina Sanchez, P4 Student

Tracy Brooks as mentor

Poster Presentation: Ospina Sanchez E, Psaras AM, Brooks T. “Combinatorial Effects of Traditional Chemotherapy with Downregulation of the MYC and/or KRAS Oncogenes in Ovarian Cancer Cells.”

American Society of Health-System Pharmacists (ASHP) Midyear Clinical Meeting & Exhibition. Anaheim, Calif. Dec. 4, 2023.

Erin Pauling, PharmD

Platform Presentation: Pauling E. “Which Bridge to Cross, Which Bridge to Burn: Updates in Periprocedural Management of Anticoagulants.”

Continuing Education, 1 credit hour. New York State American College of Clinical Pharmacy (NYS-ACCP) Clinical Meeting. Binghamton University, School of Pharmacy and Pharmaceutical Sciences. Johnson City, NY. Sep. 30, 2023.

Platform Presentation: Pauling EE, Schwier NC. “How to COEPA with Experiential Learning and Assessment Part I: An Introduction to the EPAs and COEPA.” Continuing Education, 1 credit hour. Binghamton University, School of Pharmacy and Pharmaceutical Sciences. Virtual. Jan. 23, 2024.

Platform Presentation: Pauling EE, Schwier NC. “How to COEPA with Experiential Learning and Assessment Part II: Incorporating EPAs into the Experiential Setting: Break-Out Sessions.” Continuing Education, 1 credit hour. Binghamton

University, School of Pharmacy and Pharmaceutical Sciences. Virtual. March 2, 2024.

Platform Presentation: Pauling EE, Schwier NC. “How to COEPA with Experiential Learning and Assessment Part II: Incorporating EPAs into the Experiential Setting.” Continuing Education, 1 credit hour. Binghamton University, School of Pharmacy and Pharmaceutical Sciences. Virtual. March 2, 2024.

Paul Puccio, P4 Student

Yetrib Hathout as mentor

Poster Presentation: Puccio P, Chin M, Draper E, Nunez M, Policriti B. “Proteomic Methods to Screen Ixodes Scapularis in Broome County Parks for Potential Tick-Borne Pathogens.” American Society of Health-System Pharmacists (ASHP) Midyear Clinical Meeting & Exhibition. Anaheim, Calif. Dec. 4, 2023.

Parisha

Rashid, P4 Student

Tony Davis as mentor

Poster Presentation: Rashid P, Davis T. “Development of a Thermal Shift Assay for Pseudomonas Aeruginosa Drug Discovery.” American Society of Health-System Pharmacists (ASHP) Midyear Clinical Meeting & Exhibition. Anaheim, Calif. Dec. 4, 2023.

Eric Smith, P4 Student

Mia Lussier as mentor

Poster Presentation: Smith E, Kaur J, Sherling C, Vanapalli S, Wisniewski B. “Medicare Formulary Restrictions for Glucagon-Like Peptide-1 Agonists and Sodium-Glucose CoTransporter-2 Inhibitors used in T2DM, 2019-2023.” American Society of Health-System Pharmacists (ASHP) Midyear Clinical Meeting & Exhibition. Anaheim, Calif. Dec. 4, 2023.

Rita

Spathis,

S. Research Tech.

Poster Presentation: Spathis R, Narveson S, Kuriplach DR, Huang K, Sundar T, Shulman D, Bagley E, Nagaraju K, Morales M. “Effect of JAKSTAT Inhibition with Tofacitinib and Baricitinib on disease phenotype in a Mouse Model of Myositis.” The American College of Rheumatology. San Diego, Calif. Nov. 14, 2023.

Sarah Spinler, PharmD

Platform Presentation: Spinler SA. “Pharmacy Clinical Research Microcredential for PGY1 and PGY2 Pharmacy Residents: Types of Research.” Continuing Upstate University Medical Center. Syracuse, N.Y. July 20, 2023.

Platform Presentation: Spinler SA. “Guidelines Should Only be Based on RCTs: Pro. Comparing Apples and Oranges: What to do When Guidelines Don’t Match.” Continuing Education, 1 credit hour. American College of Clinical Pharmacology (ACCP) 2023 Annual Meeting. Dallas, Tex. Sept. 12, 2023.

Poster Presentation: Sobieraj DM, Lebovitz L, Chen AMH, Carter JT, Kelsch MP, Ray ME, Spinler SA. “A Description of Required NAPLEX Preparation Courses Among US Pharmacy Programs.” American Association of Colleges of Pharmacy (AACP) Annual Meeting. Denver, Colo. July 23-24, 2023.

Poster Presentation: Spinler SA, Kelsch MP, Lebovitz L, Sobieraj DM, Chen AMH. “A Description of Required NAPLEX Preparation Courses Among US Pharmacy Schools.” American Association of Colleges of Pharmacy (AACP) Annual Meeting. Denver, Colo. July 23-24, 2023.

Poster Presentation: Kufel WD, Ali M, Spinler SA. “Evaluation of a Doctor of Pharmacy (PharmD) Capstone Research Project Experience.” American College of Clinical Pharmacy Annual Meeting, Dallas, Texas November 13, 2023. Available from: https://accpjournals.onlinelibrary.wiley.com/ doi/10.1002/jac5.1903

Nicholas Schwier, PharmD

Platform Presentation: Schwier N. “Overachievers or High Performers? The Truth, Myths, and Precepting Pearls Associated with These Challenging Learner Types.” Continuing education, 1 credit hour. New York State American College of Clinical Pharmacy (NYS-ACCP) Clinical Meeting. Binghamton University, School of Pharmacy and Pharmaceutical Sciences. Johnson City, N.Y. Sep. 30, 2023.

L. Nathan Tumey, PhD

Platform Presentation: Tumey LN. “Site Specific Conjugation.” Hanson-Wade Linker and Conjugation Summit. Boston, Mass. Aug. 22, 2023.

Platform Presentation: Tumey LN. “Demonstrating the pharmacology and utility of legumain-cleavable ADC linkers.” Hanson-Wade Linker and Conjugation Summit. Boston, Mass. Aug. 23, 2023.

Alison Van Dyke, P4 Student

Elizabeth Hageman as mentor

Poster Presentation: Van Dyke AN, Macri A, Riaz A, Vaca G, Kendra R. “Comparison of Adverse Drug Event and Medication Safety Event Rates in Supportive Oncology Biosimilars to the Reference Product.” American Society of Health-System Pharmacists (ASHP) Midyear Clinical Meeting & Exhibition. Anaheim, Calif. Dec. 4, 2023.

Sophia Ventrano, P4 Student

Mohammad Ali as mentor

Poster Presentation: Ventrano S, Ali M, Fowler E. “Identifying the Nuclear Localization Domain of Matrix Metalloproteinase-2: Implications for Cell Migration in Cancer Therapies.” American Society of Health-System Pharmacists (ASHP) Midyear Clinical Meeting & Exhibition. Anaheim, Calif. Dec. 4, 2023.

Taylor Warner, PharmD

Poster Presentation: Warner T, Hughes N, Semsick G, Harris H, Haupt C. “Evaluation of benzodiazepine use in patients without maintenance medication in the Geisinger outpatient setting.” American Society of Health-System Pharmacists (ASHP) Midyear Clinical Meeting & Exhibition. Anaheim, Calif. Dec. 6, 2023.

Platform Presentation: Warner T, Popko A, Sklanka K, Kunkel S. “Impact of Pharmacist Embedded in Primary Care Federally Qualified Health Center on HEDIS Measures for Comprehensive Diabetes Care.”  Eastern States Conference for Pharmacy Residents and Preceptors. Hershey, PA. May 7, 2024.

Jordin Watson, P4

Student

Tracy Brooks as mentor

Poster Presentation: Watson J, Psaras AM, Brooks T. “Enhancing the Responsiveness of High-grade B-cell Lymphoma to CHOP by Targeting MYC and/ or Bcl-2.” American Society of Health-System Pharmacists (ASHP) Midyear Clinical Meeting & Exhibition. Anaheim, Calif. Dec. 4, 2023.

Samantha Woods, P4 Student

Sarah Spinler and Nick Schwier as mentors

Poster Presentation: Woods SN, Baum A, Gallo S, Moravec N, Spinler S. “Outcomes Associated with the Prescription Use of Statins or Antiplatelets in Patients with Spectrums of Non-obstructive Coronary Artery Disease (NOCAD).” American Society of HealthSystem Pharmacists (ASHP) Midyear Clinical Meeting & Exhibition. Anaheim, Calif. Dec. 4, 2023.

Natalie Young, P4 Student

Melissa Morales as mentor

Poster Presentation: Young N, Savage B, Durand A, Tate C, Price C, Spathis R, Nagaraju K, Morales M. “Investigating the role of mitochondrial proteins in Post-Treatment Lyme Disease.” American Society of Health-System Pharmacists (ASHP) Midyear Clinical Meeting & Exhibition. Anaheim, Calif. Dec. 4, 2023.

Zoey Zagoria, P4 Student

Wes Kufel as mentor

Poster Presentation: Zagoria Z, Seabury RW, Steele JM, Zeineddine N, Kufel WD. “Slowing the Beat: Evaluation of Remdesivir-Associated Bradycardia.” American College of Clinical Pharmacy (ACCP) 2023 Annual Meeting. Dallas, Tex. Nov. 12, 2023.

Tao Zhang, PhD

Poster Presentation: Kinney M, Holman J, Hunt T, Hunt B, Zhang T, Chen G, Li Y, Ishaq SL. “Establishing Growth Curve Assays for Bacterial Glucosinolate Metabolism: A Study Protocol.” American Society for Nutrition Annual Meeting. Boston, Mass. July 22-25, 2023.

Poster Presentation: Holman J, Holcomb L, Colucci L, Baudewyns D, Balkan J, Chen G, Moses P, Mawe GM, Zhang T, Li Y, Ishaq SL. “Steamed broccoli sprouts alleviate gut inflammation and retain gut microbiota against DSS-induced dysbiosis.” American Society for Nutrition Annual Meeting. Boston, Mass. July 22-25, 2023.

Poster Presentation: Holcomb L, Holman J, Hurd M, Lavoie B, Colucci L, Moses P, Mawe GM, Perry E, Stratigakis A, Zhang T, Ishaq SL, Li Y. “Early life exposure to broccoli sprouts confers stronger protection against enterocolitis development in an immunological mouse model of inflammatory bowel disease.” American Society for Nutrition Annual Meeting, Boston, Mass. July 22-25, 2023.

Platform Presentation: Zhang T. “Interspecies Scaling of Transgene Products for Intramuscular and Intravesical Gene Therapies.” American College of Clinical Pharmacology (ACCP) 2023 Annual Meeting. Dallas, Tex. Sep. 10-12, 2023.

Platform Presentation: Zhang T. “IVIVE-PBPK Modeling to Predict drug transfer to Human Milk.” American Society for Clinical Pharmacology & Therapeutics (ASCPT) Early Development & Drug Safety (EDDS) Committee Meeting. Virtual. Oct 13, 2023.

Poster Presentation: Stratigakis A, Paty D, Zou P, Zhao Z, Li Y, Zhang T. “A Regression Approach for Assessing Large Molecular Drug Concentration in Breast Milk.” 2023 American Association of Pharmaceutical Scientists (AAPS) PharmSci 360. Orlando, Fla. Oct. 22-25, 2023.

of Pharmaceutical

Associate Professor
Sciences Nathan Tumey working with a student in his lab.

Our Grant Funding 2023-2024

Jared Bagley

$249,576

Intersecting genetic risk for extreme cocaine self-administration with dopamine neurotransmission

National Institute on Drug Abuse

Tracy Brooks

$10,000

AFPE Pre-Doctoral Fellowship in Pharmaceutical Sciences

American Foundation Pharmaceutical Education

Katie Edwards

$1,500

Fish Liver Samples- Materials Testing Agreement

University of Western Ontario

Yetrib Hathout

$16,938

Development of noninvasive urinary biomarker(s) for deoxyhypusine synthase (DHS) deficiency

DHPS Foundation

$535,668

Biomarker Signatures for Duchenne Muscular Dystrophy

National Institute of Neurological Disorders and Stroke

Eric Hoffman

$192,285

Clinical Trial Readiness for Monitoring Muscle Inflammation in Duchenne Muscular Dystrophy

National Center for Advancing Translational Sciences

Wesley Kufel

$1,500

Evaluation of Shorter Versus Longer Antifungal Treatment Durations for Candida Urinary Tract Infections

NYS Chapter of American College of Clinical Pharmacy

Yanyan Li

$148,718

Developing a dietary approach in the management of inflammatory bowel disease

United States Department of Agriculture via University of Michigan

$26,871

Harnessing gut microbiota to reduce inflammation using broccoli-sprout diets

National Institutes of Health via University of Maine at Orono

Mia Lussier

$10,000

Evaluation of Community Pharmacy Closures in Areas of Differing Racial and Ethnic Diversity

ASHP Research and Education Foundation

Kuo-Ching Mei

$50,000

Working towards immune mitigation and delivery of gene therapy for DMD

Foundation to Eradicate Duchenne

$354,807

Complementary Biotherapeutic Delivery Platforms for Enabling Gene Re-delivery

National Institute of General Medical Sciences

Melissa Morales

$150,000

Targeting immune and non-immune mechanisms in a mouse model of juvenile myositis

Cure JM Foundation

$84,865

Ceramide Pathway Dysregulation in Duchenne Muscular Dystrophy

Foundation to Eradicate Duchenne

Kanneboyina Nagaraju

$50,000

I-Corps: Translation Potential of UltraFlexible, Lipsomal, Lidocaine Gel

National Sciences Foundation

Nicholas Schwier

$4,000

Preceptor Perceptions of Overachieving and High-Achieving Pharmacy Student Behaviors

American Association of College of Pharmacy

L. Nathan Tumey

$142,698

Fluticasone-based ADCs for the Treatment of IBD

Bighat Biosciences

$50,000

Validation of Novel Antibody Drug Conjugates for the Treatment of Cancer

State University of New York

$40,000

SUNY Research Seed Grant Program

State University of New York

$4,280

Mitigating ADA Through Site-specific Conjugation Technology

National Institute of General Medical Sciences

$308,528

Exploiting the Hydrophobic Glycosyl Pocket of IgG1 for Imaging and Drug Delivery Applications

National Institute of General Medical Sciences

$303,056

Legumain to the rescue: A new ADC linker strategy to address the limitations of cathepsin cleavage

National Institute of General Medical Sciences

$150,000

Binghamton Excellence in Entrepreneurship and Discovery (ART) Accelerating Research Translation

National Sciences Foundation

Tao Zhang

$500,000

A Systemic Approach to Predict the Excretion of Antidepressants into Breast Milk

US Food and Drug Administration

OTHER FUNDING

Foundation Gift:

Mother Cabrini Health Foundation

$160,000 for the Pharmacy Tech Training Scholarship

SOPPS Faculty, Staff, and Student Achievement

Highlights 2023-2024 (July 1, 2023 – June 30, 2024)

Dr. Rachel Klosko

• Preceptor of the Year Award for PGY1 Pharmacy Residency Program at Guthrie Robert Packer Hospital

Dr. Wes Kufel

• Top 2% of Researchers in the World by Stanford University Study Recognition in 2023

• American College of Clinical Pharmacy New Clinical Practitioner Award (2023)

• Faculty Preceptor of the Year, Binghamton University School of Pharmacy and Pharmaceutical Sciences 2023

• Chair, American College of Clinical Pharmacy Infectious Diseases Practice and Research Network (2023-2024)

• Vice-Chair, Board of Pharmacy Specialities Board Certified Infectious Diseases Specialty Council (20232024)

• Vice-Chair, Society of Infectious Diseases Pharmacists InterOrganizational and Engagement Committee (2023-2024)

• National Judge, American Society of Health-System Pharmacists National Clinical Skills Competition (2023)

Marissa Langett

• Binghamton University Bearcat Award for Outstanding Service and Support

Dr. Emily Leppien

• 2024 Provost’s Award for Excellence in Interprofessional Education, Binghamton University

Bruce Maine

• Binghamton University Bearcat Award for Outstanding Service and Support

Dr. Kanneboyina Nagaraju

• 2024 Promotion to SUNY Distinguished Professor, the highest rank in the SUNY system

Lynda Ruffini

• Binghamton University Bearcat Award for Outstanding Service and Support

Interim Director of Experiential Education
Marissa Langett in her office at the School of Pharmacy.

Clinical Assistant Professor of Pharmacy Practice Rachel

talking with students during a TRUST event.

Klosko

SOPPS Publications 2023-2024

Journal Articles

Abe Z, Smith E, Pauling EE. GLP-1 receptor agonists for weight loss management. Cardiology Today. 2023 Nov 2.

Aitken C, Huskens N, Bushby K, Noble K, Hamerlik P, Kaye E, Kobayashi D, Matthew R, McCall J, Nazarian J, Plummer R, Rahman R, Lopez J, Nagaraju K. A NEW INTERNATIONAL, MULTIDISCIPLINARY ACCELERATOR PROGRAMME FOR NOVEL BRAIN TUMOUR THERAPIES. Neuro-Oncology. 2024;26.

Alaba TE, Holman JM, Ishaq SL, Li Y. Current Knowledge on the Preparation and Benefits of Cruciferous Vegetables as Relates to In Vitro, In Vivo, and Clinical Models of Inflammatory Bowel Disease. Curr Dev Nutr. 2024 Apr 17;8(5):102160. doi: 10.1016/j.cdnut.2024.102160. PMID: 38779039; PMCID: PMC11108850.

Arbitman L, Chen S, Kim B, Lee M, Zou P, Doughty B, Li Y, Zhang T. Assessment of Infant Exposure to Antidepressants through Breastfeeding: A Literature Review of Currently Available Approaches. Pharmaceutics. 2024 Jun 22;16(7):847. doi: 10.3390/pharmaceutics16070847. PMID: 39065544; PMCID: PMC11280233.

Bello L, Sabbatini D, Fusto A, Gorgoglione D, Borin GU, Penzo M, Riguzzi P, Villa M, Vianello S, Calore C, Melacini P, Vio R, Barp A, D’Angelo G, Gandossini S, Politano L, Berardinelli A, Messina S, Vita GL, Pedemonte M, Bruno C, Albamonte E, Sansone V, Baranello G, Masson R, Astrea G, D’Amico A, Bertini E, Pane M, Lucibello S, Mercuri E, Spurney C, Clemens P, Morgenroth L, GordishDressman H, McDonald CM, Hoffman EP; CINRGDNHS Investigators; Pegoraro E. The IAAM LTBP4 Haplotype is Protective Against DystrophinDeficient Cardiomyopathy. J Neuromuscul Dis. 2024;11(2):285-297. doi: 10.3233/JND-230129. PMID: 38363615; PMCID: PMC10977446.

Bennett KK, Schwier NC. Should direct oral anticoagulants be used to treat protein C or S deficiency? JAAPA. 2023 Jul 1;36(7):8-10. doi: 10.1097/01.JAA.0000937288.04720.58. PMID: 37368848.

Chahine EB, Beedle AM, Carter CW, Clem JR, Nuziale B, Tromp KM, Woods ZT, Vos SS, Matsumoto RR. Innovative ideas, strategies, and resources to attract students to the pharmacy profession: Report of the 2023-2024 AACP Student Affairs Committee. Am J Pharm Educ. 2024 Aug;88(8):100730. doi: 10.1016/j.ajpe.2024.100730. Epub 2024 Jun 7. PMID: 38852678.

Chen A, Re RN, Davis TD, Tran K, Moriuchi YW, Wu S, La Clair JJ, Louie GV, Bowman ME, Clarke DJ, Mackay CL, Campopiano DJ, Noel JP, Burkart MD. Visualizing the Interface of Biotin and Fatty Acid Biosynthesis through SuFEx Probes. J Am Chem Soc. 2024 Jan 17;146(2):1388-1395. doi: 10.1021/ jacs.3c10181. Epub 2024 Jan 4. PMID: 38176024.

Cluck DB, Chastain DB, Murray M, Durham SH, Chahine EB, Derrick C, Dumond JB, Hester EK, Jeter SB, Johnson MD, Kilcrease C, Kufel WD, Kwong J, Ladak AF, Patel N, Pérez SE, Poe JB, Bolch C, Thomas I, Asiago-Reddy E, Short WR. Consensus recommendations for the use of novel antiretrovirals in persons with HIV who are heavily treatment-experienced and/or have multidrugresistant HIV-1: Endorsed by the American Academy of HIV Medicine, American College of Clinical Pharmacy. Pharmacotherapy. 2024 May;44(5):360382. doi: 10.1002/phar.2914. PMID: 38853601.

Cluck DB, Chastain DB, Murray M, Durham SH, Chahine EB, Derrick C, Dumond JB, Hester EK, Jeter SB, Johnson MD, Kilcrease C, Kufel WD, Kwong J, Ladak AF, Patel N, Pérez SE, Poe JB, Bolch C, Thomas I, Asiago-Reddy E, Short WR. Consensus recommendations for the use of novel antiretrovirals in persons with HIV who are heavily treatmentexperienced and/or have multidrug-resistant HIV-1: Endorsed by the American Academy of HIV

Medicine, American College of Clinical Pharmacy: An executive summary. Pharmacotherapy. 2024 May;44(5):354-359. doi: 10.1002/phar.2913. PMID: 38853605.

Cohen M, Spyropoulos AC, Goodman SG, Spinler SA, Bonaca MP, Redling TM, Visveswaran G, Sohal S. Rivaroxaban Versus Apixaban: A Comparison Without a Simple Solution. Mayo Clin Proc Innov Qual Outcomes. 2024 Jun 11;8(4):321-328. doi: 10.1016/j.mayocpiqo.2024.05.004. PMID: 38974528; PMCID: PMC11223068.

Collins CD, Dumkow LE, Kufel WD, Nguyen CT, Wagner JL. ASHP/SIDP Joint Statement on the Pharmacist’s Role in Antimicrobial Stewardship. Am J Health Syst Pharm. 2023 Oct 25;80(21):1577-1581. doi: 10.1093/ajhp/zxad164. PMID: 37879095.

Dana SR, Nichols SD, McCall KL, Piper BJ. Pronounced State Level Disparities in Medicaid Prescribing of Buprenorphine for Opioid Use Disorder (2019-2020). J Stud Alcohol Drugs. 2023 Aug 30. doi: 10.15288/jsad.22-00373. Epub ahead of print. PMID: 37650858.

Dang UJ, Damsker JM, Guglieri M, Clemens PR, Perlman SJ, Smith EC, Horrocks I, Finkel RS, Mah JK, Deconinck N, Goemans NM, Haberlová J, Straub V, Mengle-Gaw L, Schwartz BD, Harper A, Shieh PB, De Waele L, Castro D, Yang ML, Ryan MM, McDonald CM, Tulinius M, Webster RI, Mcmillan HJ, Kuntz N, Rao VK, Baranello G, Spinty S, Childs AM, Sbrocchi AM, Selby KA, Monduy M, Nevo Y, Vilchez JJ, Nascimento-Osorio A, Niks EH, De Groot IJM, Katsalouli M, Van Den Anker JN, Ward LM, Leinonen M, D’Alessandro AL, Hoffman EP. Efficacy and Safety of Vamorolone Over 48 Weeks in Boys With Duchenne Muscular Dystrophy: A Randomized Controlled Trial. Neurology. 2024 Mar 12;102(5):e208112. doi: 10.1212/ WNL.0000000000208112. Epub 2024 Feb 9. PMID: 38335499; PMCID: PMC11067696.

sets on antibiotic use metrics among hospitalized adult patients. Infect Control Hosp Epidemiol. 2024 May;45(5):609-617. doi: 10.1017/ice.2023.293. Epub 2024 Jan 25. PMID: 38268340; PMCID: PMC11027081.

Kufel WD, Zagoria Z, Blaine BE, Steele JM, Mahapatra R, Paolino KM, Thomas SJ. Daptomycin Plus Oxacillin for Persistent MethicillinSusceptible Staphylococcus aureus Bacteremia. Ann Pharmacother. 2023 Aug 5:10600280231189888. doi: 10.1177/10600280231189888. Epub ahead of print. PMID: 37542415.

Leppien EE, Pauling EE, Smith E, Wisniewski B, Carpenter A, Schwier NC. Pain management considerations in patients living with both pain syndromes and cardiovascular diseases and disorders. Pharmacotherapy. 2024 Feb;44(2):184196. doi: 10.1002/phar.2897. Epub 2024 Jan 25. PMID: 38049207.

Li JM, Cosler LE, Harausz EP, Myers CE, Kufel WD. Methenamine for urinary tract infection prophylaxis: A systematic review. Pharmacotherapy. 2024 Feb;44(2):197-206. doi: 10.1002/phar.2895. Epub 2023 Nov 28. PMID: 37986168.

Li X, Sabbatini D, Pegoraro E, Bello L, Clemens P, Guglieri M, van den Anker J, Damsker J, McCall J, Dang UJ, Hoffman EP, Jusko WJ. Assessing Pharmacogenomic loci Associated with the Pharmacokinetics of Vamorolone in Boys with Duchenne Muscular Dystrophy. J Clin Pharmacol. 2024 Apr 29. doi: 10.1002/jcph.2446. Epub ahead of print. PMID: 38682893.

Liu EY, McCall KL, Piper BJ. Pronounced StateLevel Disparities in Prescription of Cannabinoids to Medicaid Patients. Med Cannabis Cannabinoids. 2023 Jun 19;6(1):58-65. doi: 10.1159/000531058. PMID: 37404688; PMCID: PMC10315157. Lussier ME, Gionfriddo MR, Graham JH, Wright EA. Factors Affecting Prescribing of Type 2 Diabetes Medications in Older Adults within an Integrated Healthcare System. J Gen Intern Med. 2023 Oct 2. doi: 10.1007/s11606-023-08435-6. Epub ahead of print. PMID: 37783983.

Madera JD, Ruffino AE, Feliz A, McCall KL, Davis CS, Piper BJ. Declining but Pronounced State-Level Disparities in Prescription Opioid Distribution in

the United States. Pharmacy (Basel). 2024 Jan 16;12(1):14. doi: 10.3390/pharmacy12010014. PMID: 38251408; PMCID: PMC10801547.

Manko CD, Ahmed MS, Harrison LR, Kodavatiganti SA, Lugo N, Konadu JO, Khan F, Massari CA, Sealey TK, Addison ME, Mbah CN, McCall KL, Fraiman JB, Piper BJ. Retrospective study investigating naloxone prescribing and cost in US Medicaid and Medicare patients. BMJ Open. 2024 May 1;14(5):e078592. doi: 10.1136/bmjopen-2023-078592. PMID: 38692729; PMCID: PMC11086430.

Maybee DV, Cromwell CR, Hubbard BP, Ali MAM. MMP-2 regulates Src activation via repression of the CHK/MATK tumor suppressor in osteosarcoma. Cancer Rep (Hoboken). 2023 Dec 8;7(2):e1946. doi: 10.1002/cnr2.1946. Epub ahead of print. PMID: 38064181; PMCID: PMC10849928.

McCall KL, Doughty BJ, Piper BJ, Naik H, Bange S, Leppien EE. First generation antipsychoticassociated serious adverse events in women: a retrospective analysis of a pharmacovigilance database. Int J Clin Pharm. 2024 Apr;46(2):515-521. doi: 10.1007/s11096-023-01693-8. Epub 2024 Feb 5. PMID: 38315306.

McCall KL, Hennig KR, Abe ZT, Dattler DN, Hurd KL, Portnoy SL, Zagoria ZJ. Rising cases of drug-induced pulmonary fibrosis: Analysis of the Food and Drug Administration Adverse Event Reporting System (FAERS) database, 2000-2022. Pharmacoepidemiol Drug Saf. 2024 May;33(5):e5797. doi: 10.1002/pds.5797. PMID: 38680101.

McGinley JM, Pauling EE, Rouhana N, Podolak CE, Cowen N, Hennig K, Shipe SL, Young SR, Rattinger GB. Preparing students to address the social determinants of health in integrated care settings. Clin Teach. 2023 Sep 4:e13646. doi: 10.1111/tct.13646. Epub ahead of print. PMID: 37665034.

Mei KC, Thota N, Wei PS, Yi B, Bonacquisti EE, Nguyen J. Calreticulin P-domain-derived “Eat-me” peptides for enhancing liposomal uptake in dendritic cells. Int J Pharm. 2024 Mar 25;653:123844. doi: 10.1016/j.ijpharm.2024.123844. Epub 2024 Jan 23. PMID: 38272193; PMCID: PMC10994729.

Morales M, Spathis R, Narvesen S, Kuriplach D, Huang K, Bagley E, Eybs M, King M, Shulman D, MacKinnon A, Lawlor M, Nagaraju K. P263

Targeting the innate immune system to block acute inflammatory responses and increase AAV viral transduction of skeletal muscle in mdx mice. Neuromuscul Disord. 2023 Oct;33(Suppl 1):S148. doi: https://doi.org/10.1016/j.nmd.2023.07.326

Patterson ME, Ellingrod VL, Feola DJ, Kunda NK, Mei KC, Oestreich JH, Farrell DF, Giacomini KM. Report of the 2023-2024 AACP Research and Graduate Affairs Committee. Am J Pharm Educ. 2024 Aug;88(8):100745. doi: 10.1016/j. ajpe.2024.100745. Epub 2024 Jun 27. PMID: 38944279.

Phung K, Crabtree N, Connolly AM, Furlong P, Hoffman EP, Jackowski SA, Jayash SN, Johnson A, Koujok K, Munns CF, Niks E, Rauch F, Schrader R, Turner C, Vroom E, Weber DR, Wong BL, Guglieri M, Ward LM, Wong SC. Moving Beyond the 2018 Minimum International Care Considerations for Osteoporosis Management in Duchenne Muscular Dystrophy (DMD): Meeting Report from the 3rd International Muscle-Bone Interactions Meeting 7th and 14th November 2022. J Neuromuscul Dis. 2023 Nov 16. doi: 10.3233/JND-230176. Epub ahead of print. PMID: 37980681.

Rahman MM, Wang J, Wang G, Su Z, Li Y, Chen Y, Meng J, Yao Y, Wang L, Wilkens S, Tan J, Luo J, Zhang T, Zhu C, Cho SH, Wang L, Lee LP, Wan Y. Chimeric nanobody-decorated liposomes by self-assembly. Nat Nanotechnol. 2024 Feb 19. doi: 10.1038/s41565-024-01620-6. Epub ahead of print. PMID: 38374413.

Rebold N, Alosaimy S, Pearson JC, Dionne B, Taqi A, Lagnf A, Lucas K, Biagi M, Lombardo N, Eudy J, Anderson DT, Mahoney MV, Kufel WD, D’Antonio JA, Jones BM, Frens JJ, Baumeister T, Geriak M, Sakoulas G, Farmakiotis D, Delaportas D, Larew J, Veve MP, Rybak MJ. Dalbavancin Sequential Therapy for Gram-Positive Bloodstream Infection: A Multicenter Observational Study. Infect Dis Ther. 2024 Mar;13(3):565-579. doi: 10.1007/s40121024-00933-2. Epub 2024 Mar 1. PMID: 38427289; PMCID: PMC10965835.

Roy R, Dang UJ, Huffman KM, Alayi T, Hathout Y, Nagaraju K, Visich PS, Hoffman EP. A population-

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