Vascular Connections The Official Newspaper of the Vascular Annual Meeting
w e d n e s d ay t h u r s d ay
SOCIETY FOR VASCULAR SURGERY • VASCULAR AND ENDOVASCULAR SURGERY SOCIETY • JUNE 12-15, 2019 • GAYLORD NATIONAL RESORT & CONVENTION CENTER
RESIDENT RESEARCH AWARD PAPER
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onhealing wounds in patients with diabetes are a major cause of morbidity and mortality in the United States and are increasing at an alarming rate. Equally concerning, the current “standard of care” leaves 70% of diabetic wounds unhealed. Given this substantial impact on patient outcomes and health care expenditure, a critical unmet need exists for improved understanding of the pathophysiology of diabetic wounds to develop effective treatments. This year’s SVS Foundation’s Resident Research Award is being presented to Frank M. Davis, MD, of the University of Michigan, Ann Arbor, for his research on the epigenetic regulation of the prostaglandin pathway in macrophages during type 2 diabetic wound healing. Dr. Davis, and his mentor Katherine Gallagher, MD, also from the University of Michigan, investigated how impairments in the innate immune system in patients with diabetes promote chronic inflammation and impair wound healing. Dr. Davis will present his award-winning research in the von Liebig Forum, Thursday, June 13, discussing the role of specific epigenetic enzymes in the dictation of macrophage phenotype in wound tissue. The talk will cover how diabetes alters those enzymes to influence a deleterious phenotype that promotes inflammation and delays wound healing. “Our laboratory specifically looks at the role of monocytes/macrophages in the inflammatory phase of wound
J esse Stafford /G etty I mages P lus
Macrophages, Regulation, and Impaired Diabetic Wound Healing While SVS members are busy with the Vascular Annual Meeting, family members can take in all the attractions that nearby Washington, D.C., has to offer. Here, the statue of Abraham Lincoln greets the dawn. The Lincoln Memorial is just one of dozens of historic sites in the nation’s capital.
WEDNESDAY-THURSDAY DR. DAVIS
Spotlight
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here’s a lot happening these first 2 days of VAM. Here are just a few you might want to attend (all at the Gaylord National Resort & Convention Center).
DR. GALLAGHER
healing and how perturbation in the local environment – such as those seen in diabetes – affects monocyte /macrophage phenotype and ultimately wound healing” said Dr. Davis. The talk will specifically cover the cyclo-oxygenase (COX)-2/prostaglandin E2 (PGE2) axis. Using both a murine model and human wound samples Dr. Davis demonstrates that PGE2 is substantially elevated in diabetic wound macrophages. Further, aberrant PGE2 production
Wounds continued on page 2
Wednesday, June 12 10:15 a.m. to 1:15 p.m. – Learn about ensuring the appropriate venous care during Postgrad Course 3, presented in collaboration with the American Venous Forum (Potomac C). 10:30 a.m. to 12:15 p.m. – The International Young Surgeon Competition gets a dedicated time slot this year (Maryland B). 4 to 5 p.m. – Experts will offer input on managing complex IVC filter problems in the first “Ask the Expert” session of 2019 (Potomac 1-2) 5 to 6:30 p.m. – The audience gets to help choose a winner at the Clinical Research Seed Grant Challenge, which will feature three surgeonscientists presenting their research proposals to a panel of experts (Potomac C).
Thursday, June 13 8 to 8:30 a.m. – The 2019 Vascular Annual Meeting kicks off at the Opening Ceremony (Potomac A/B). 10 a.m. to 6:30 p.m. – Enjoy coffee breaks and lunch, attend Vascular Live presentations, and visit exhibitor booths for the latest in technology and devices (Exhibit Hall B). 10:30 a.m. to 12 p.m. – The question that weighs on the minds of many vascular surgeons: How can we use evidence-based medicine to improve outcomes, reduce costs, and ensure appropriate utilization of resources? Hear the discussion at the E. Stanley Crawford Critical Issues Forum (Potomac A/B). 12 to 1 p.m. – Interest in outpatient and office-based settings for vascular procedures? Attend OBL 101 (the Office Vascular Care Pavilion in Exhibit Hall B). 5 to 6:30 p.m. – Talk to exhibitors, talk to your friends, and enjoy food and beverages at the Opening Reception, which also includes the Interactive Poster Session (Exhibit Hall B). VC