OUR TECHNOLOGY
SP PuraBead® Edge is a next-generation strong CEX adsorbent, featuring a sulphopropyl (SP) group attached to our advanced 65 µm PuraBead® Edge base bead.
PuraBead® Edge resin is engineered for high-resolution polishing applications, offering short residence times and low back pressure. This resin is designed to enhance separation resolution, ideal when required for the capture and polish of positively charged species.
Efficiently remove unwanted mispaired species and aggregates from bispecific antibody feeds or reduce host cell proteins (HCPs) from CHO IgG with ease. Designed for seamless integration into your workflow, this solution is available in high-throughput columns and large-scale, process-ready slurry to meet your purification needs.
Key features
• High binding capacity: For example, 95 mg/mL for Lysozyme
• Excellent flow properties: Supports flow rates up to 400 cm/hr
• Efficient cleaning & sanitization: Stable in 0.5–1.0 M NaOH for stringent cleaning protocols
• Robust & long-lasting: Engineered for extended usability through multiple cycles
Advantages
• Improved resolution using out 65 μm agarose bead
• Optimal balance of flow rate, binding capacity and resolution to maximize productivity
• Demonstrated performance in antibody applications
• Efficient processing of large volumes
For more information on this or any other matters, please do not hesitate to contact us at sales@astrea-bio.com
PRODUCT FORMATS
Bulk manufacture & supply
Astrea Bioseparations in volumes sufficient to meet the requirements of the largest biomanufacturing processes. Adsorbent batches are produced in Astrea Bioseparations’ controlled environment manufacturing facility under an ISO 9001 quality system.
Regulatory support
Our ion exchange adsorbents are manufactured in Astrea Bioseparations’ controlled environment manufacturing facility under an accredited ISO 9001 quality system and are supported by comprehensive regulatory support files.
Ordering information
For small orders up to 500 mL, please visit our web shop.
We also offer a range a range of pre-packed SP PuraBead® Edge columns and larger pack sizes for
Gel slurry
Column kits
Commitment to quality
Astrea Bioseparations is honored to support the biopharmaceutical industry with products and services that help bring life-saving and improving medicines to market. Regardless of process scale, we are ready to build Purity by Design into each process to ensure quality and speed to market.
Evolve® R 5 mL 4300-00005-FG00561
Astrea Bioseparations: A complete toolbox for antibody purification
Astrea Bioseparations provides a broad range of purification resins for mAb and other antibody formats, supporting both capture and polishing steps. Our toolbox approach enables tailored purification workflows using products such as Fabsorbent™ F1P HF, HCPure™, Q PuraBead®, and SP PuraBead® Edge. We offer high-throughput screening formats to streamline discovery and purification, driving efficiency in biopharmaceutical development and commercialization.
Technical support
Astrea Bioseparations provides expert technical support to help optimize purification strategies. Our chromatography specialists are available to assist with process development, troubleshooting, and scalability considerations.
