

OUR TECHNOLOGY
Astrea Bioseparations offers refresh kits for the entire Evolve® Process Column range, providing an economical and convenient alternative to complete replacement of the hardware for single-use applications. The kit contains replacement parts for all the wetted components of the column, enabling straightforward renewal of the columns for continued use.
Astrea Bioseparations, in collaboration with Delta Precision Ltd, have developed the Evolve® product range, consisting of eight cost-effective, highperformance process columns.
A unique feature of the Evolve® Process Column range is the ability to replace the wetted flow path with refresh kits, providing significant cost savings in terms of both time and money in comparison to complete column replacement and subsequent product clearance and cleaning validation protocols.
Available for the entire column range, the kits contain all the components required to refresh the Evolve® columns, including extensive instructions for simple replacement of the necessary components, including


Hygienic
• Prevents cross contamination between multiple protein applications
• Eliminates the need to prove clearance of previous product & cleaning validation
Economical
• Significant cost savings in comparison to purchasing a complete new column
Environmentally Friendly
• Minimize use of harsh solvents and acids
• Retain resins after use
• Prevent cross-contamination
• As supplied the refresh kit and all its parts are fully recyclable. Please check with local authorities before disposing any parts to comply with your local regulations/guidelines
THE RANGE
70 mm
AA07CRK 100 mm
AA10CRK 140 mm
200 mm
250 mm
350 mm
450 mm
600 mm
Kits include:
• Acrylic Tube & Scale Label
• Adjuster & Bottom Flow Tube
• Flow Tube Seals
• Pipespool Elbow
• Adjuster Seal
AA14CRK
AA20CRK
AA25CRK
AA35CRK3
AA45CRK
AA60CRK

• Sanitary Clamp Adaptor
• Adjuster Bed Support Assembly
• Bottom Bed Support Assembly
• Top & Bottom Buffer Seals
• Adjuster Flow Cell, Bottom Flow Cell & Antijets• Spares kit, including adjuster/flow tube seals & bed support assemblies

Commitment to Quality
Astrea Bioseparations is honored to support the biopharmaceutical industry with products and services that help bring life-saving and improving medicines to market. Regardless of process scale, we are ready to build Purity by Design into each process to ensure quality and speed to market.
Technical Support
Astrea Bioseparations are experts in chromatography development and can help optimize all process parameters including column packing
Astrea Bioseparations also supply an extensive range of replacement parts & accessories for the Evolve® Process Column range
Evolve® Column Diameter
Product Code


