Adsorbent selection guide
Kappa & Lambda light chains, IgGs & fragments, Fab fragments, F(ab’)2, ScFv, domain antibodies, antibody-drug conjugates, bispecifics
Glycosylated IgG capture & other mixed-mode interations
Host cell proteins, host cell DNA, aggregates
Primary capture, host cell protein removal
Host cell DNA, aggregates
pDNA purification using pDNAHERO® technology
Polishing (separation of supercoiled pDNA)
Isoagglutinnin removal
Recombinant albumin capture (high ligand density)
Plasma-derived albumin capture (high selectivity)
Albumin fusion protein
IVIG
Primary capture blood clotting factors (requires affinity polish)
C1-esterase inhibitor protein capture
C1-esterase inhibitor protein polish
Capture & purification of plasma-derived proteins
Fc region
Kappa & Lambda light chains, IgGs & fragments, Fab fragments, F(ab’)2, ScFv, domain antibodies, antibody-drug conjugates, bispecifics
Glycoprotein & glycosolated protein removal
Capture & polish using mixed-mode interactions
Botulinum toxin purification
Insulin purification
Alkaline phosphotase purification
Phosphate-binding protein purification (bind phosphate groups)
Serine protease capture
Primary capture, host cell protein removal
Host cell DNA, aggregates
Endotoxin from E. coli
AAV capture
HCP removal
Empty/Full separation