Autism Spectrum Disorder is a very intrigued term, sheltering a number of other neurodevelopmental disorders like Autism, Rett Syndrome, Asperger’s syndrome, Childhood Disintegrating Disorders etc. It includes some enigmatic conditions that have their origin in altered cellular interactions and environmental factors; during embryonic development. Unfortunately, statistical analysis has witnessed the increased prevalence of ASD; still, there are no effective drugs to manage its core symptoms. The advent of stem cell therapy for Autism Spectrum Disorder has presented a new hope to repair the root cause of its development.